Episodes

10h ago

This episode covers: • FDA Loosens Supplement Warning Labels The FDA is considering a rule change that would allow supplement companies to include the DSHEA disclaimer only once per package rather than next to every claim. Dave explains why fewer visible warnings could make marketing look more like medical claims, and why biohackers should treat labels as advertising rather than evidence. He shares how to protect yourself now: add one variable at a time, run baseline labs, and rely on data instead of packaging. Source: https://www.nbcnews.com/health/health-news/fda-supplements-warning-label-rule-change-rfk-jr-rcna249321 • Quantum Sensors for Early Heart Attack Detection Mayo Clinic is testing a contactless heart-monitoring system called CardiAQ using quantum magnetic sensors and AI noise filtering. The device reads subtle electromagnetic signatures from the heart and compares them to invasive angiography. Dave breaks down why earlier detection of ischemia could shift heart care from reactive treatment to proactive screening — and why building baseline metrics like VO₂max, blood pressure and HRV today will pay off when next-gen diagnostics arrive. Source: https://www.sandboxaq.com/press/sandboxaq-collaborates-with-mayo-clinic-on-novel-cardiac-diagnostics • Sauna Detox for Microplastics Emerging research shows that sweating meaningfully removes plastic-related chemicals like BPA and phthalate metabolites from the body, often more efficiently than blood or urine alone. Sauna use amplifies this effect by increasing circulation, mobilizing stored toxins from tissues, and accelerating sweat-based excretion. When you combine regular heat exposure with reduced environmental plastic contact, you create a powerful detox strategy that targets a chemical burden once thought unavoidable. Dave breaks down how sauna protocols can support toxin elimination, improve cardiovascular resilience, strengthen autonomic balance, and help counteract the metabolic and hormonal disruptions linked to microplastics in modern life. Source: https://superage.com/can-you-sweat-out-microplastics-in-the-sauna/ • Psychedelics and Longevity Biomarkers Bryan Johnson treated a guided psilocybin experience as a structured longevity experiment, collecting nearly 250 biomarkers including CGM, stress markers, HRV and Kernel brain imaging. The experiment revealed a surprising metabolic change: mean glucose dropped 8 percent, variability fell 11 percent, and estimated HbA1c moved from 4.7 to 4.4 — similar to months of metformin but after a single session. Dave explores the emerging idea that neuroplastic events might influence glucose regulation through brain-pancreas signaling, while emphasizing the need for supervised, legal use and proper clinical trials. Source: https://www.businessinsider.com/bryan-johnson-trip-on-mushrooms-five-hours-live-2025-12 • A Mitochondrial Protein that Extends Mouse Lifespan Researchers boosted the mitochondrial protein COX7RP and extended mouse lifespan by ~6.6 percent while improving insulin sensitivity, lipid handling, endurance and liver fat metabolism. COX7RP supports formation of mitochondrial “supercomplexes,” improving respiratory efficiency and ATP generation. Dave explains how this reinforces lifestyle levers — strength training, aerobic capacity, stabilizing blood sugar — as tools that likely preserve supercomplex architecture and mitochondrial resilience. Source: https://www.eurekalert.org/news-releases/1109082 All source links provided for direct access to the original research and reporting. This episode is designed for biohackers, longevity seekers and high-performance listeners who want practical strategies rooted in cutting-edge science. Dave Asprey translates emerging research into actionable upgrades for your biology — from metabolism and mitochondria to nervous system health, detox, and prevention. New episodes every Tuesday, Thursday, Friday, and Sunday. Keywords: FDA supplement rule change, supplement warning labels, DSHEA disclaimer removal, supplement regulation risks, quantum cardiac scanner, Mayo Clinic heart attack detection, AI heart monitoring, early ischemia detection technology, sauna detox evidence, sweating out toxins research, BPA phthalate sweat studies, microplastics sauna myth, Bryan Johnson psilocybin experiment, psychedelic longevity research, psychedelic metabolic reset, glucose control psychedelics, HbA1c psilocybin results, continuous glucose monitor insights, mitochondria lifespan research, COX7RP protein aging study, mitochondrial supercomplex benefits, ATP energy output aging, metabolic flexibility longevity, biohacking news update, anti-aging science breakthroughs, evidence-based longevity tools, biological age biomarkers Thank you to our sponsors! -BEYOND Conference 2026 | Register now at https://beyondconference.com/ -BodyGuardz | Visit https://www.bodyguardz.com/ and use code DAVE for 25% off. Resources: • Subscribe to my weekly newsletter: https://substack.daveasprey.com/welcome • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 - Intro 0:18 - Story 1: FDA Supplement Label Changes 1:43 - Story 2: CardiAQ Heart Scanner 2:59 - Story 3: Saunas and Microplastics 4:58 - Story 4: Psychedelics and Blood Sugar 8:22 - Story 5: Mitochondrial Longevity Research 10:29 - Weekly Wrap-Up See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

1d ago

This episode explores how intimacy, desire, and erotic states function as powerful tools for healing, nervous system regulation, and personal transformation. You’ll learn why certain forms of conscious erotic play create genuine altered states of consciousness, not through substances or external compounds, but through the body’s own internal chemistry. This conversation reframes sexuality as a core aspect of health, performance, and emotional resilience rather than something separate from personal development or spirituality. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Kimi Inch is a somatic therapist and educator with over 20 years of experience working at the intersection of intimacy, conscious kink, trauma healing, and embodied self awareness. Her work centers on helping individuals and couples access deep states of connection and healing through structured, consent based practices that engage breath, sensation, power dynamics, and presence. She is known for creating safe, grounded spaces where people can explore desire in ways that support lasting nervous system regulation and authentic self expression. Together, Dave Asprey and Kimi explore how erotic experiences trigger specific neurochemical responses including oxytocin, serotonin, endorphins, and adrenaline, and why this internal cocktail mirrors the effects of many psychedelic and somatic healing modalities. They discuss surrender, safety, attunement, and aftercare as essential components of integration, and why unexpressed desire often leaks into leadership, relationships, and performance in destructive ways. You’ll Learn: • How erotic states create real altered states of consciousness through internal neurochemistry • Why intimacy can function as a powerful form of nervous system regulation and trauma healing • The difference between conscious desire and compulsive behavior • How surrender, safety, and attunement reshape emotional and relational patterns • Why suppressed desire leaks into work, leadership, and relationships • What makes healthy power dynamics healing rather than harmful • The role of aftercare and integration in long term transformation • How erotic intelligence connects to vitality, authenticity, and human performance Thank you to our sponsors! -EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE for 40% off. -Calroy | Head to https://calroy.com/dave for an exclusive discount. -Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee , and the father of biohacking . With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS) . Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: conscious kink, erotic healing, intimacy and healing, altered states of consciousness, somatic therapy, nervous system safety, erotic intelligence, surrender and intimacy, power dynamics psychology, trauma and embodiment, aftercare and integration, neurochemistry of intimacy, oxytocin bonding, endorphins and pleasure, consent based intimacy, asking for what you want, suppressed desire, authenticity and intimacy, biohacking intimacy, Dave Asprey intimacy, Kimi Inch Biohack Resources: • Kimi's Website: https://andmorepresents.com/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 - Trailer 1:25 - Altered States Through Kink 4:41 - Learning to Receive 12:17 - Play Parties Explained 19:31 - Life Force Energy 26:40 - Desire vs Compulsion 28:23 - The Kidnapping Session 35:53 - Aftercare and Integration 45:35 - Bedroom = Life 52:50 - CEOs and Surrender See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

3d ago

This episode lays out the blueprint for having healthier children later in life by treating preconception as the most important window for human health. You’ll learn why fertility is not just about getting pregnant, but about building the biological foundation that shapes a child’s brain development, metabolism, immune function, and long term resilience. This conversation reframes infertility as a meaningful signal to pause, repair, and prepare, instead of something to override or rush past. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Dr. Ann Shippy is a board-certified internal medicine physician, certified functional medicine practitioner, and a leading expert in preconception health and fertility optimization. A former IBM chemical engineer, she brings a rare systems-based and data-driven approach to uncovering the root causes of infertility, chronic disease, and hormonal dysfunction. Through her Austin-based medical practice, she has helped men and women restore fertility naturally and conceive healthy children well into their 40s using advanced lab testing, precision supplements, and targeted functional medicine strategies. Together, Dave Asprey and Dr. Shippy explore why childhood illness and infertility are rising at the same time, and how environmental toxins, mold exposure, microbiome imbalances, sleep disruption, and chronic inflammation undermine fertility in both men and women. They discuss the role of mitochondria, circadian rhythms, thyroid health, testosterone, and epigenetics in reproductive health, and why IVF should not be the first step without addressing underlying biological dysfunction. You’ll Learn: • Why preconception matters more than pregnancy for long term child health • How sperm and egg quality act as biological time capsules for future generations • Why infertility functions as a warning signal instead of a random failure • How environmental toxins and mold exposure disrupt fertility and mitochondrial health • The connection between fertility, longevity, and overall human performance • Why sleep, circadian rhythm, and stress strongly influence reproductive hormones • The role of thyroid function and testosterone in fertility and metabolism • When IVF makes sense and why it should not bypass foundational health work Thank you to our sponsors! Dave's Biohacking Holiday Gift Guide | Go to https://daveasprey.com/giftguide/ to explore the full guide. GOT MOLD? | Go to http://gotmold.com/shop and use DAVE10 to save 10% and see what’s in your air. Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee , and the father of biohacking . With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS) . Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: preconception health, fertility optimization, healthy pregnancy preparation, sperm and egg quality, epigenetic inheritance, generational health, infertility root causes, environmental toxins fertility, mitochondrial health fertility, functional medicine fertility, hormone balance fertility, IVF alternatives, natural fertility strategies, longevity and reproduction, human performance biology, sleep and fertility, circadian rhythm health, supplements for fertility, smarter not harder health, Dave Asprey fertility, Human Upgrade fertility, Dr. Ann Shippy, Ann Shippy MD, Ann Shippy fertility expert, Ann Shippy preconception, The Preconception Revolution Resources: • Dr Shippy’s New Book ‘The Preconception Revolution’: https://annshippymd.com/the-preconception-revolution/ • Dr Shippy’s Website: https://annshippymd.com/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:45 — Introduction 2:49 — Rising Childhood Illnesses 5:47 — Ann’s Fertility Journey 10:41 — Environmental Toxins & Mold 12:42 — Circadian Rhythms & Sleep 16:42 — IVF Considerations 19:54 — Infertility as a Warning Sign 22:20 — Egg Selection & Biology 26:43 — Men’s Role in Fertility 28:16 — Supplements for Fertility 36:49 — Thyroid & Fertility 42:20 — Testosterone & Fertility 50:40 — Stress & Trauma 53:56 — Spiritual Aspects 59:15 — Relationship Health See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

5d ago

Try TrueDark Glasses: https://truedark.com/?coupon-code=DAVETUBE&sc-page=shop Kill your zombie cells with: http://www.qualialife.com/davenad Your brain has a built-in switch that controls deep sleep but for most people, it’s turned off. In this video, Dave Asprey exposes the hidden factors blocking your deep sleep. He shows how small changes to posture, meal timing, and lighting can reactivate your brain’s sleep control center so you sleep deeper, recover faster, and wake up refreshed, all in 6.5 hours a night. *** Dave's Biohacking Holiday Gift Guide | Go to https://daveasprey.com/giftguide/ to explore the full guide. *** Thank you to our sponsors! • ECHO Water | Go to http://echowater.com/dave and use code DAVE10 for 10% off your ECHO Flask. • AirDoctor | Go to https://airdoctorpro.com/daveasprey and save up to $300 on Air Purifiers. Timestamps 00:00 – The Hidden Sleep Switch Nobody Talks About 01:35 – The Root Causes of Bad Sleep 02:13 – The Invisible Force Ruining Your Sleep 03:48 – The Worst Sleeping Positions (and Why) 04:30 – Correct Setup for Side and Back Sleepers 06:23 – Why Food Timing Destroys Deep Sleep 08:29 – The 3-Hour Rule 09:33 – The Circadian Rhythm Problem in Modern Life 11:30 – The Brain’s Master Clock 12:30 – Mimicking Nature with Morning and Evening Light 14:20 – Proof That Light Manipulation Works 15:05 – How to Reset Your Circadian Rhythm Step-by-Step Resources: • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Connect with Dave Asprey! Website: https://daveasprey.com TikTok: https://www.tiktok.com/@daveaspreyofficial Instagram: https://www.instagram.com/dave.asprey/ Facebook: https://www.facebook.com/Daveaspreyofficial/ X: https://x.com/daveasprey YouTube: https://www.youtube.com/c/daveaspreybpr The Human Upgrade Podcast: Instagram: https://www.instagram.com/TheHumanUpgradePodcast/ Facebook: https://m.facebook.com/Thehumanupgrade/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Dec 12

If you want more time, better energy, and a calmer mind, this episode gives you a blueprint for achieving it. Host Dave Asprey talks with entrepreneur Jonathan Swanson, who explains how delegation functions as a powerful form of biohacking that frees cognitive load, improves sleep quality, protects your mitochondria from chronic stress, and opens space for longevity, brain optimization, supplements, fasting, ketosis, and the full Human Upgrade approach. Jonathan shows how eliminating low value tasks can reclaim hours every day and upgrade your human performance far more than people realize. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Jonathan Swanson is the Founder and Chairman of Thumbtack and Athena, two global companies he scaled to more than one thousand team members each. He has raised over seven hundred million dollars from leading investors including Sequoia Capital, Google Capital, and Blackstone. At Thumbtack he built one of the top marketplaces for local services. At Athena he created an elite academy for executive assistants and leadership development. Jonathan also served in the West Wing for the President’s chief economic advisor, giving him rare insight into time leverage, decision making, and performance under pressure. Jonathan breaks down why overloaded to do lists elevate stress hormones, reduce neuroplasticity, interfere with recovery, and sabotage longevity goals. He explains how removing decision fatigue improves metabolism and cognitive function, how AI can accelerate human support instead of replacing it, and why even small forms of leverage increase ambition, resilience, and overall life satisfaction. Jonathan shares real examples from scaling billion dollar companies, building global teams, managing his own health routines, and designing systems that create more time for family, recovery, and meaningful work. You’ll Learn: • Why leverage comes before ambition, not after, and how that shift changes what you believe is possible in your life • How Jonathan went from 16 to 18 hour days and polyphasic sleep to becoming a “time billionaire” through ruthless delegation • The cardinal sin of delegation, why doing it yourself feels faster at first, and how that belief traps you in busywork • The stages of delegation, from single tasks to projects to goals to “clairvoyant delegation,” where you first hear about a task when it is already done • How to start at any budget level, from using AI as a starter assistant, to hiring directly on global platforms, to working with a fully trained Athena EA • Practical ways an assistant can support biohacking, sleep optimization, supplements, lab tracking, family logistics, and even creative life projects • How to build trust, set boundaries, and protect security when you work with remote assistants who have access to sensitive parts of your life • Why human plus AI assistants beat AI alone, and how the next generation of support will supercharge human performance instead of replacing it • How to think about your hourly rate so you stop doing tasks that kill your metabolism, focus, and long term longevity Thank you to our sponsors! -BEYOND Conference 2026 | Register now at https://beyondconference.com/ -BrainTap | Go to http://braintap.com/dave to get $100 off the BrainTap Power Bundle. -Essentia | Go to https://myessentia.com/dave and use code DAVE for $100 off The Dave Asprey Upgrade. -Generation Lab | Go to http://generationlab.com/ , use code Dave20 for $20 off, and see what your body’s really doing behind the surface. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee , and the father of biohacking . With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS) . Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: time leverage, personal delegation, executive assistant training, Athena assistant, cognitive load reduction, decision fatigue relief, daily workflow optimization, biohacking time freedom, human plus AI support, inbox offloading, calendar management, task automation, overwhelm reduction, founder performance, global talent recruitment, delegation ladder, clairvoyant delegation, lifestyle efficiency, home logistics support, entrepreneurial time scaling Resources: • Athena Website: Go to https://athena.com/upgrade for a generous discount! • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 - Trailer 1:30 - Introduction 2:44 - From 18 Hour Days to Delegation 6:42 - Dave’s EA Journey 10:43 - Overcoming Shame 12:21 - Finding Trust 15:00 - Delegation Options 18:20 - Never Lift a Finger 22:32 - Clairvoyant Delegation 27:58 - Human + AI Future 30:42 - Security and Boundaries 43:10 - Creative Uses 47:24 - Night Watch 51:37 - Do Less, Do More See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Dec 11

Your jaw influences far more than your face. This episode shows you how jaw strength shapes cognition, posture, airway health, sleep, metabolism, and overall human performance. You will learn how targeted jaw training increases cranial blood flow, improves neuromuscular coordination, strengthens airway stability, and stimulates facial muscles that modern diets no longer challenge. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey talks with Brandon Harris, founder and CEO of Jawzrsize. Brandon developed the device after multiple severe injuries, including a shattered jaw, months of immobilization, and a 13 day coma. His recovery forced him to rebuild his jaw strength from zero and revealed how deeply the jaw affects posture, oral health, proprioception, and cognitive function. Brandon’s experience as a mixed martial artist and his early training of the masseter muscle guided the creation of a safe, medical grade jaw resistance system that now has small clinical data supporting improvements in strength, facial tone, Bruxism relief, and TMJ balance. You will hear how jaw alignment influences the nervous system, why weak jaws contribute to sleep apnea, how saliva flow ties oral health to gut health, and why resistance training for the jaw produces structural benefits the modern soft diet fails to provide. Host Dave Asprey explains how full range jaw training supports cranial stimulation, nitric oxide signaling, fascia activation, posture correction, and neuromuscular coordination throughout the body. This episode also explores how jaw mechanics connect to biohacking principles like brain optimization, sleep optimization, longevity, neuroplasticity, metabolic signaling, and strength based anti aging. This is essential listening for anyone focused on biohacking, human performance, posture mechanics, airway stability, TMJ function, oral microbiome health, anti aging, supplements that support structural function, nervous system training, and practical tools that create fast visible results. You’ll Learn: • Why jaw strength acts as a foundational marker for performance and longevity • How jaw alignment shapes posture, proprioception, and neuromuscular firing • Why weak jaws contribute to sleep apnea, snoring, and airway collapse • How jaw training improves Bruxism, clenching, and TMJ tension • What increased cranial blood flow does for cognition and focus • How saliva production supports oral and gut health • Why modern diets shrink facial structure and weaken masseter strength • How jaw resistance training improves facial tone and reduces wrinkle depth • Why athletes use jaw activation to sharpen hand eye coordination • How range of motion training strengthens bone through piezoelectric signaling • Why even five minutes a day creates noticeable results in facial tone and alignment Thank you to our sponsors! -HeartMath | Go to https://www.heartmath.com/dave to save 15% off. -fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. -Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee , and the father of biohacking . With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS) . Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: jaw strength training, TMJ alignment exercise, cranial blood flow stimulation, facial muscle resistance training, bruxism clenching relief, sleep apnea jaw support, oral microbiome improvement, saliva flow activation, jaw posture neuromuscular signaling, masseter hypertrophy training, facial tone anti aging, proprioception jaw connection, airway stability strengthening, hunters gatherers chewing mechanics, tongue plate neck activation, molar alignment biomechanics, jaw range of motion training, piezoelectric bone stimulation, oral health gut health pathway, forward jaw positioning airflow Resources: • Go to https://jawzrsize.com/ ‘Dave15’ for 15% off! • Dave's Biohacking Holiday Gift Guide | Go to https://daveasprey.com/giftguide/ to explore the full guide. • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 - Trailer 1:20 - Intro 2:20 - Brandon’s Accident and Recovery 5:00 - Jawzrsize Origin Story 6:16 - The Science of Jaw Strength 17:56 - Clinical Results and User Experience 22:48 - Jaw Health, Posture and Systemic Effects 27:54 - Microplastics 35:59 - Athletic Performance and Neuromuscular Strength 52:57 - Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Dec 9

Most people stay locked in a constant sympathetic state without realizing it, which drains focus, sleep quality, emotional balance, and long-term resilience. This episode gives you a science backed path to retrain your nervous system, improve heart rate variability, and shift out of stress on command using focused ultrasound technology that targets the vagus nerve. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey talks with Jon Hacker, CEO of NeurGear and creator of ZenBud. Jon is a biomedical engineer who has dedicated his career to bridging neuroscience and daily wellness. His work includes peer reviewed clinical research on anxiety, PTSD, autonomic regulation, and non invasive vagus nerve stimulation. He is one of the first innovators to bring focused ultrasound out of the lab and into a practical wearable designed to help people regulate state, build resilience, and create more conscious control over their biology. In this conversation, Dave and Jon break down how ultrasound activates the auricular branch of the vagus nerve, why most electrical vagus nerve devices fail, and what actually happens in the first three to five minutes when the system begins shifting out of sympathetic activation. Jon explains how early trauma wires the autonomic system, why chronic stress is often physiological rather than psychological, and how daily stimulation strengthens vagal tone through Hebbian learning. They also explore how HRV reflects hidden state changes, how nervous system training supports clearer thinking and better emotional regulation, and why this type of tech matters as AI, algorithms, and modern stressors continue to push people into dysregulated states. You’ll Learn: • Why sympathetic dominance is so widespread in the modern environment • How the vagus nerve influences stress, recovery, inflammation, and emotional balance • What makes focused ultrasound more precise than electrical vagus nerve stimulation • How ZenBud produced a 78 percent remission rate in clinical anxiety research • How early trauma alters autonomic patterns and keeps people in hidden fight or flight • How three to five minutes of stimulation can reset state during panic or overwhelm • Why daily use strengthens vagal tone and builds long term resilience • How HRV training, consciousness practices, and nervous system workouts fit together • Why noninvasive brain interfaces may become the safer future path as AI advances This episode is essential for anyone interested in biohacking, stress physiology, nervous system training, emotional regulation, HRV, meditation, trauma recovery, longevity, and building a more adaptable brain and body. It gives you a practical look at how the autonomic system really works and how focused ultrasound may change the future of human performance. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee , and the father of biohacking . With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS) . Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: focused ultrasound vagus nerve stimulation, autonomic nervous system regulation, sympathetic dominance recovery, auricular vagus nerve activation, heart rate variability training, anxiety remission ultrasound, PTSD autonomic modulation, Hebbian learning vagal tone, parasympathetic state shift, ultrasound neuromodulation research, trauma induced nervous system wiring, panic attack recovery tools, non invasive brain interface, emotional regulation biohacking, stress physiology retraining, early adverse events autonomic impact, vagus nerve inflammation pathway, TBI secondary injury prevention, ultrasound neural action potentials, HRV resilience protocols Resources: • Go to http://www.zenbud.health/dave and use code ‘Dave15’ for a discount! You’ll also receive: 3 months of ear buds 3 months of silicone gel 1 copy of Heavily Meditated 1 bottle of Daily Zen supplement by Vatellia Life (60 day supply) • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 – Trailer 2:00 – Intro 8:04 – Understanding Stress and the Vagus Nerve 14:14 – Jon’s Story and Why He Built ZenBud 16:17 – How Vagus Nerve Stimulation Works 21:07 – Using ZenBud and Clinical Results 24:23 – Why We’re All So Anxious 30:54 – Longevity, TBI and Recovery 44:01 – The Future of Brain Computer Interfaces 50:54 – Closing Thank you to our sponsors! -LYMA | Go to https://lyma.sjv.io/gOQ545 and use code DAVE10 for 10% off the LYMA Laser. -TRU KAVA | Go to https://trukava.com/ and use code DAVE10 for 10% off. -BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 to save 20% off your first order of PerfectAmino. -Leela Quantum Tech | Check out all HEAL360 products and research and get 10% off at https://leelaq.com/DAVE . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Dec 7

Most people think fasting is just about skipping breakfast. But what if 72 hours without food could actually reverse aging? In this video, Dave Asprey breaks down what really happens when you fast for 3 days—and why short fasts don’t reach the deep repair zone your body is built for. You’ll learn: The 3 critical stages your body passes through during fasting How autophagy turns on and begins cellular repair What mistakes destroy your progress (like bad refeeding or skipping electrolytes) How to properly prepare, fast, and recover safely Why fasting can make your mitochondria stronger, your mind sharper, and your cells younger *** Dave's Biohacking Holiday Gift Guide | Go to https://daveasprey.com/giftguide/ to explore the full guide. *** Timestamps 0:00 - Why 16-hour fasts don’t reach real fat burning 0:54 - The myth of aging and what doctors overlook 1:48 - How modern life damages your mitochondria 2:48 - How fasting restores your body’s repair mode 3:39 - Understanding the phases of fasting 4:58 - Why short fasts cut results short 5:34 - Day 1 of fasting 6:45 - Day 2 of fasting 7:22 - Day 3 of fasting 8:24 - Common fasting mistakes that harm your body 9:35 - How to prepare before your fast 10:31 - The right way to refeed afterward 11:14 - Listening to your body’s signals and responses Thank you to our sponsors! -BrainTap | Go to http://braintap.com/dave to get $100 off the BrainTap Power Bundle. Resources: • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Connect with Dave Asprey! Website: https://daveasprey.com TikTok: https://www.tiktok.com/@daveaspreyofficial Instagram: https://www.instagram.com/dave.asprey/ Facebook: https://www.facebook.com/Daveaspreyofficial/ X: https://x.com/daveasprey YouTube: https://www.youtube.com/c/daveaspreybpr The Human Upgrade Podcast: Instagram: https://www.instagram.com/TheHumanUpgradePodcast/ Facebook: https://m.facebook.com/Thehumanupgrade/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Dec 5

Vitamin C, copper peptides, and glutathione behave very differently once you understand how skin absorbs nutrients at the cellular level. This episode shows you how to target collagen production, strengthen mitochondria, improve detox capacity, and upgrade skin density with pharmaceutical grade delivery systems that outperform conventional skincare. You learn why most topical antioxidants never reach their intended targets, how intracellular copper changes longevity pathways, why glutathione affects everything from pigmentation to detox, and how to build a streamlined routine that matches the way high level biohackers actually age. These strategies can help you improve collagen, elasticity, hair density, mitochondrial function, and whole body performance with fewer steps and far more impact. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey talks with Dr. Nayan Patel, a pharmacist, wellness expert, and industry leader who has worked with physicians since 1999 to design custom medications and patient specific protocols. He has been the pharmacist of choice for celebrities, CEOs, and medical professionals seeking precision level formulations. Dr. Patel is the author of The Glutathione Revolution, which summarizes more than a decade of clinical research on glutathione. His team created a patented transdermal technology that delivers glutathione systemically through the skin, and he has since expanded this work to include advanced peptides and new delivery systems that improve absorption far beyond standard topical products. He also developed the Auro GSH Antioxidant Delivery System, a skincare line that uses pharmaceutical grade ingredients at potent concentrations to achieve deeper penetration and more reliable biological effects. Together they break down why vitamin C acts as a stimulant that drives collagen rather than a classic antioxidant, how GHK copper peptide thickens aging skin, and why retinoids often speed up cell turnover at the cost of long term resilience. Dr. Patel explains the difference between cosmetic grade and injectable grade peptides, why purity matters when a delivery system pushes molecules deep into the skin, and how zinc overuse has created widespread copper deficiency that affects hair, metabolism, and mitochondrial health. Dave shares his own protocols for using GHK, glutathione, and vitamin C, along with practical dosing strategies that create visible changes in skin density within four to six weeks. You will learn: • How vitamin C stimulates collagen and why glutathione regenerates oxidized antioxidants • How GHK copper peptide improves elasticity, firmness, and structural integrity • Why purity, molecular size, and delivery tech determine whether peptides actually reach target tissues • How topical copper supports intracellular stores and influences hair health and metabolism • Why zinc overload causes silent copper deficiency and what it means for longevity • How targeted glutathione improves detox, pigmentation, and oxidative stress • The fastest protocol for visible skin density improvements and how long results take to show • How to combine these tools with lasers and skin procedures for stronger outcomes Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee , and the father of biohacking . With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS) . Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: GHK copper peptide, topical glutathione delivery, dextrin absorption technology, intracellular copper uptake, vitamin C collagen stimulation, antioxidant regeneration, cosmetic peptide purity, injectable grade peptides, zinc copper imbalance, mitochondrial skin health, hair follicle regeneration, oxidative stress reduction, glutathione detox support, peptide based skincare, collagen crosslinking support, DMAE skin firmness, CoQ10 topical benefits, skincare biohacking, longevity dermatology, pharmaceutical transdermal systems Resources: • Go to https://aurowellness.com/ ‘DAVE10’ for a discount! • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 - Trailer 1:30 - Introduction 5:51 - Delivery Technology and How It Works 9:34 - Product Development and Formulations 21:29 - Application and Usage Guidelines 32:17 - Hair Growth and Specific Concerns 37:22 - Copper, Deficiency and Body Systems 40:52 - Special Topics and Protocols 52:00 - Dosing Protocols and Closing See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Dec 4

If you care about longevity, mitochondria, cardiovascular health, or feeling sharper every day, this episode gives you a clear look at the breakthrough technology that could reshape how supplements are made. Host Dave Asprey talks with Ilan Sobel, CEO of BioHarvest Sciences, about a new way to produce plant compounds at industrial scale without ever growing the plant. Their Botanical Synthesis platform creates highly pure, clinically validated molecules that support blood flow, brain function, metabolic health, and cellular energy with remarkable consistency and little to no environmental waste. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Ilan brings more than two decades of experience in global biotech and consumer health, and under his leadership BioHarvest has grown its flagship product VINIA into one of the fastest growing plant-based supplements in North America. He explains how the company uses plant cell biology and AI guided cultivation to deliver resveratrol, polyphenols, and other high value compounds with superior bioavailability, purity, and measurable clinical effects on arterial dilation, driven by increasing nitric oxide and resulting in improving physical energy, mental alertness and reducing oxidative stress You will learn: • Why traditional extraction wastes most of the plant and creates inconsistent supplement quality • How Botanical Synthesis produces highly bioavailable polyphenols without insecticides, herbacides, fungicides, solvents, or worrying about heavy metal levels. • Why VINIA increases arterial dilation, improves blood flow, and supports healthy nitric oxide levels • How reducing ET1 strengthens vascular health in ways typical nitric oxide supplements cannot • Why better blood flow supports brain performance, mental alertness, and daily physical energy • What clinical studies show about resveratrol absorption, bioavailability, and 12 hour activity in the bloodstream • How piceid resveratrol crosses the blood brain barrier to support cognitive function • Why BioHarvest is developing olive cell compounds like verbascoside for liver fat reduction and cognitive aging • How future saffron cell technology may influence mood, stress, and cognitive health • Why this approach offers major advantages for longevity, anti-aging strategies, and high-performance biology Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee , and the father of biohacking . With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS) . Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: plant cell biology, Botanical Synthesis, Vinia polyphenols, piceid resveratrol, nitric oxide production, ET1 reduction, arterial dilation, vascular flexibility, blood flow optimization, brain oxygenation, cognitive alertness, oxidative stress reduction, bioavailable polyphenols, grape cell technology, olive cell compounds, verbascoside research, saffron cell cultivation, clinical blood flow studies, endothelial function, longevity supplementation **Visti www.vinia.com/Dave - for a generous discount on your next purchase** Resources: • VINIA Website: www.vinia.com/Dave • BioHarvest Website: https://bioharvest.com/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 - Trailer 1:30 - How BioHarvest Works 5:23 - Piceid Resveratrol & Clinical Studies 13:37 - Blood Flow & Cardiovascular Benefits 17:08 - Brain Health & Cognitive Effects 20:07 - VINIA Product Line & Pricing 22:33 - Nitric Oxide Mechanism & ET1 26:39 - Chews & Hydration Mix 36:35 - VINIA Heroes Program 41:19 - Olive Cell Technology & Verbascoside 45:13 - Pharmaceutical Implications 51:30 - Saffron Development See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Dec 2

This episode shows you how light, vibration, and frequency-based technology can shift your brain state in minutes, unlock deep neuroplasticity, release stored trauma, and create coherence that normally takes years of meditation or psychedelic training. You will learn how these tools support performance, resilience, mitochondria, emotional regulation, and advanced biohacking. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with master healer Raffaele Gianfrancesco , whose work draws on energy medicine, Egyptian color healing, vibroacoustics, and light based entrainment. Raffaele trained in the Barbara Brennan lineage and spent years developing methods that shut down the default mode network, activate the thalamocortical circuit, and move people into deep meditative and altered states within minutes. His technology has attracted the attention of consciousness researchers, advanced meditation schools, ketamine clinics, and U. S. Air Force programs studying human resilience and pilot performance. Dave and Raffaele break down how vibroacoustic sound, harmonics, cymatics, and flickering light therapy guide the brain into gamma, delta, epsilon, and high resonance states that support clarity, emotional release, and rapid state change. Raffaele explains how vibration affects fascia and trauma storage, how light influences the cerebrospinal fluid and pineal gland, and why coherence is the key to shifting consciousness. They discuss ketamine assisted therapy, remote viewing, the Monroe Institute, the relationship between frequencies and brain states, the history of flickering light therapy, and how certain frequencies help loosen trauma patterns stored in the body. You’ll Learn: • How vibroacoustic sound and coherent light shut down the default mode network • Why fascia, trauma memory, and cerebrospinal fluid respond to vibration • How flicker based entrainment maps to gamma, delta, and theta brain states • Why the Air Force studies these tools for resilience and reaction speed • How ketamine combines with vibration and light to improve neuroplasticity • Why coherence, awe, and safety cues are essential for deep emotional release • What cymatics, harmonics, and frequency patterns reveal about consciousness Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee , and the father of biohacking . With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS) . Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: vibroacoustic therapy, flickering light therapy, consciousness technology, brainwave entrainment, cymatics healing, trauma release tools, ketamine neuroplasticity, default mode network reset, cerebrospinal fluid flow, energy medicine, Barbara Brennan healing, harmonic frequencies, gamma brain states, theta induction, somatic healing, astral plane experiences, remote viewing training, Monroe Institute methods, coherence training, vibration based meditation ** https://roxiva.com/dave - for $1,000 off when you purchase the light and vibroacoustic bed together. ** Resources: • RoXiva Website: https://roxiva.com/dave • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: • 0:00 - Introduction • 1:14 - Vibroacoustic Technology • 4:08 - Energy Medicine and Healing • 10:06 - Coherence and Harmonics • 13:47 - Flickering Light Therapy • 16:10 - Stanislav Grof and LSD • 18:49 - Soul Sickness and Consciousness • 21:53 - Ayahuasca and Astral Plane • 28:36 - Psychedelics and Ego Death • 31:23 - Ketamine and Neuroplasticity • 37:31 - Trauma and Presence • 41:08 - Harmonics and Brain Frequencies • 44:04 - Flicker Fusion and Safety • 46:43 - Remote Viewing and Monroe Institute • 48:23 - Cerebrospinal Fluid and Consciousness • 50:32 - Product Details and Pricing See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 30

In 1999, a Silicon Valley millionaire on the brink of collapse took one mysterious sip atop a frozen Tibetan mountain - and everything changed. That moment sparked a global movement, rewrote the rules of fat and energy, and turned an ancient secret into a modern revolution. 00:00 – The Dying Millionaire 00:40 – The Mountain That Changed Everything 01:30 – The Birth of Bulletproof Coffee 02:40 – When the World Took Notice 03:45 – The Fat Lie We All Believed 04:45 – The Truth About Good Fats 06:00 – Escaping the Sugar Trap 07:15 – Stop Counting Calories 09:00 – Why Inflammation Keeps You Fat 10:40 – Eat Less Often, Not Less Food 12:00 – The Exercise Myth 13:40 – The Hidden Toxins Problem 15:20 – Fixing the Root Cause 17:40 – The Power of Mitochondria 20:00 – One Sip That Changed Everything Thank you to our sponsors! -KILLSwitch | If you’re ready for the best sleep of your life, order now at https://www.switchsupplements.com/ and use code DAVE for 20% off. -EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE for 40% off. Connect with Dave Asprey! Website: https://daveasprey.com TikTok: https://www.tiktok.com/@daveaspreyofficial Instagram: https://www.instagram.com/dave.asprey/ Facebook: https://www.facebook.com/Daveaspreyofficial/ X: https://x.com/daveasprey YouTube: https://www.youtube.com/c/daveaspreybpr The Human Upgrade Podcast: Instagram: https://www.instagram.com/TheHumanUpgradePodcast/ Facebook: https://m.facebook.com/Thehumanupgrade/ Resources: • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 28

Most people think you need sweat, strain, or long workouts to upgrade circulation, metabolism, and energy. What if your body could unlock all of that while you stand still? This episode reveals how to get a full body workout by doing absolutely nothing, and why a few minutes of targeted vibration can activate nitric oxide, improve microcirculation, calm your nervous system, and relieve the hidden damage from sitting all day. Host Dave Asprey shows you why the simplest biohack in the room might be the most powerful one you are not using. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Dr. Tommy Rhee, DC, a board-certified chiropractor known for his innovative approach to sports medicine and regenerative therapy. Dr. Rhee has treated professional athletes, starting NFL quarterbacks, and everyday people who want better mobility and faster recovery. He served as the official team chiropractor for the Tampa Bay Buccaneers and worked with multiple UCLA athletic programs. He also created RheeGen, a patent-pending topical transdermal stem cell cream that introduces a non-invasive path to tissue repair and pain relief. His book, The Future of Regenerative Medicine, outlines how topical stem cell treatments can transform performance and healing. Dr. Rhee’s background as a U.S. Navy aircrew member aboard S-3 Viking jets gives him a precision-driven understanding of human performance, resilience, and stress adaptation. In this episode, Dr. Rhee explains why whole body vibration works as a cheat code for circulation, fascia mobility, balance, mood, and nitric oxide activation. He shows how vibration increases microcirculation in places your workouts never reach, why it boosts lymphatic flow better than walking, and how it sends rapid-fire sensory signals that improve proprioception and stress recovery. You also learn why older adults benefit even more from this simple tool, how athletes use it as a warmup to conserve energy, and why three plane vibration dramatically outperforms cheap two dimensional devices. Dave and Dr. Rhee show you how to pair vibration with fasting, ketosis, nootropics, supplements, Danger Coffee, and Smarter Not Harder style training for maximum biohacking efficiency. You’ll Learn: • How to mimic the benefits of a full workout while standing still • Why nitric oxide drives circulation, longevity, and metabolic health • How vibration accelerates lymphatic drainage and clears stagnation • Why whole body vibration improves balance, sensory speed, and neuroplasticity • How athletes warm up with vibration to protect energy reserves • Why triplanar vibration beats two dimensional devices for real results • How vibration supports pelvic floor strength and erectile function • How to use vibration for joint protection, fascia mobility, and mitochondrial activation • The daily protocol Dr. Rhee uses for stress relief, mood, and brain optimization Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee , and the father of biohacking . With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS) . Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: vibration plate benefits, power plate workout, whole body vibration therapy, nitric oxide boost naturally, improve circulation fast, lymphatic drainage at home, fix leg swelling quickly, better than walking workout, passive exercise machine, joint friendly fitness, biohacking circulation hack, vibration plate for balance, how to increase microcirculation, proprioception training at home, vibration plate for seniors, rebounder vs vibration plate, fix poor circulation in legs, vibration therapy recovery, power plate warmup routine, best vibration plate for home use **Discount on your next Power Plate: https://powerplate.com/dave ** Resources: • Power Plate Website: https://powerplate.com/dave • Dr. Tommy Rhee’s Website: https://rheegen.com/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 - Trailer 0:45 - Introduction: Whole Body Vibration 2:12 - Biological Activation Explained 4:05 - Nitric Oxide and Circulation 5:57 - Power Plate vs Walking 8:19 - Shearing Force and Fascia 11:25 - Planking and Exercise Variations 13:31 - Common Mistakes 15:03 - Microcirculation and Lymphatics 19:02 - Benefits for Young Athletes 22:15 - Types of Vibration Machines 25:21 - Proprioception and Balance 27:08 - Pro Athletes and Warm-Up 34:08 - Benefits for Women 35:35 - Benefits for Men 36:13 - Mood and Stress Relief 37:21 - Power Plate Deal and Recommendations 38:53 - Frequency Settings 40:58 - Power Plate vs Rebounder 44:03 - Usage for Ill or Elderly 46:53 - Closing Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 27

Prepare to rethink surgery, healing, anesthesia, and recovery. This episode gives you a complete, high-performance playbook for surgical preparation and accelerated healing, built on biohacking, functional medicine, neuroprotection, and mitochondrial resilience. You will learn how to recover up to three times faster, protect your brain from anesthesia related inflammation, and enter any procedure with the stability and metabolic readiness of an elite performer. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey talks with Dr. Cameron Chesnut, a facial plastic surgeon trusted by the world’s high performers. Patients travel from every corner of the globe for his minimally invasive results that look natural, rejuvenated, and untouched. He is known for progressive regenerative medicine techniques, brain safe anesthesia protocols, advanced postoperative recovery strategies, and a personal commitment to performance readiness that mirrors the mindset of elite athletes. His methods bridge functional medicine, metabolism, supplements, sleep optimization, nootropics, and regenerative science to transform the entire surgical experience. Together, they reveal how to avoid the hidden pitfalls that create postoperative brain fog, inflammation, mitochondrial dysfunction, and slow recovery. You learn how to work with your anesthesiologist, avoid harmful drug combinations, and stack ketones, fasting, NAD, glutathione, stem cell rich fat grafts, IV therapy, and hyperbarics for rapid healing. Dr. Chesnut explains why fillers migrate, why general anesthesia often disrupts cognition, how exogenous ketones stabilize neurons, and how regenerative peptides, ketosis, circadian timing, and nutritional density shift the biology of recovery. You’ll Learn: • How Host Dave Asprey prepares his brain and mitochondria before anesthesia • Why standard anesthesia protocols increase neuroinflammation and cognitive dysfunction • How to use ketamine and dexmedetomidine instead of benzos, opiates, and amnesia drugs • Why fillers migrate and how regenerative fat grafting outperforms traditional filler • How exogenous ketones enhance neuronal stability during anesthesia • Why hyperbarics, red light, PEMF, and IV therapy shorten recovery time • How peptides like BPC, GHK copper, and TB4 support tissue repair • Why metabolic health, carnivore leaning nutrition, and real protein accelerate healing • How nicotine influences angiogenesis and when it can help • The real difference between healing fast and healing well • How to structure your recovery environment for sleep optimization and better outcomes • Why elite performers treat surgery like an athletic event and prepare the same way • How to talk to your surgical team so your biology stays protected and optimized Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee , and the father of biohacking . With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS) . Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Regenerative surgery optimization, anesthesia brain protection, postoperative cognitive dysfunction, accelerated surgical healing, functional medicine surgery prep, ketamine conscious sedation, dexmedetomidine anesthesia protocol, mitochondrial recovery support, stem cell rich fat grafting, surgical hyperbaric therapy, exogenous ketone neuroprotection, fasting preparation, nootropic assisted recovery, peptide tissue repair, filler migration correction, angiogenesis enhancement, circadian prep, sleep optimized anesthesia, metabolic healing strategy, nicotine angiogenesis Thank you to our sponsors! -Essentia | Go to https://myessentia.com/dave and use code DAVE for $100 off The Dave Asprey Upgrade. -ECHO Water | Go to http://echowater.com/dave and use code DAVE10 for 10% off your ECHO Flask. -ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. -Caldera + Lab | Go to https://calderalab.com/DAVE and use code DAVE at checkout for 20% off your first order. Resources: • Cameron’s Clinic: https://www.clinic5c.com/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 - Trailer 2:05 - Pre-Surgery Optimization 5:41 - Stem Cells and Fat Transfer 9:28 - Brain Safe Anesthesia 15:43 - Propofol Alternatives 21:06 - Non-Opioid Pain Control 27:22 - Recovery Protocols 29:11 - Xenon Gas Insights 31:02 - Racetams and Brain Protection 33:18 - IV Glutathione 43:24 - Ketones for Surgery 44:06 - Growth Hormone and Peptides 55:57 - Nicotine and Healing 58:37 - Surgical Lighting 1:05:23 - Filler Migration 1:15:18 - Final Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 25

Breathwork is one of the most powerful tools in biohacking, yet most people only experience the surface level techniques. When you use it the right way, breathwork can upgrade your brain, strengthen your nervous system, improve sleep, and open awareness states that amplify longevity and human performance. This episode features Ishan Shivanand, a globally celebrated yogic scholar, mental health researcher, and bestselling author who was raised in the monasteries of India under Mahasiddha Avdhoot Shivanand. He carries one of the world’s oldest Shiv Yogi lineages and created the clinically validated Yoga of Immortals method, which has helped millions reverse anxiety, depression, insomnia, burnout, and trauma. Together, Host Dave Asprey and Ishan reveal how lineage level breath practices shape consciousness, neuroplasticity, and emotional resilience. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey and Ishan explore the full arc of ancient yogic training, from how breathwork directs prana through the body to how chanting alters brain states, emotional regulation, and nervous system function. They break down the role of visualization in building neuroplasticity, the symbolism and physics of sacred sound, and the science of moving awareness through the spine. The conversation moves into rarely discussed topics including the yogic art of choosing one’s death, how advanced practitioners leave the body, the meaning of immortality in spiritual traditions, and how dharma shapes whether long life becomes a blessing or a burden. You will hear how ancient monks trained through martial arts, mantra repetition, sacred geometry, gold symbolism, alchemy, and the cultivation of higher states of consciousness, and how these practices compare to modern biohacking tools like fasting, ketosis, nootropics, supplements, sleep optimization, functional medicine, and mitochondrial support. This episode shows you how Eastern mystical training and Western performance science intersect and how these teachings fit naturally within the Smarter Not Harder framework. This conversation also covers plant medicine, psychedelics, and the difference between ancient ceremonial use and modern recreational misuse. You will hear how lineage based training uses breath, awareness, and mantra to alter redox balance, regulate the autonomic nervous system, strengthen energy production, and shape brain optimization at the deepest levels. You’ll Learn: • Why breathwork changes brain states faster than basic meditation and how it drives neuroplasticity • How chanting affects the vagus nerve, emotional regulation, and nervous system balance • How visualization strengthens nerve pathways, trauma resolution, and sleep optimization • The meaning behind sacred sound, vibration, and the origins of consciousness in ancient lineage training • Why monks train with martial arts, mantra repetition, and sacred geometry to enhance awareness • How yogic philosophy approaches immortality, choosing one’s death, and leaving the body consciously • Why dharma shapes whether long life becomes a blessing or a curse • How plant medicine differs when used ceremonially versus recreationally • How to integrate these teachings into your own longevity, performance, and human potential strategy Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: advanced breathwork techniques, prana movement training, mantra induced trance states, sacred sound vibration science, visualization neuroplasticity practice, yogic spinal awareness training, autonomic nervous system regulation, ancient Himalayan lineage meditation, art of conscious death practice, yogic immortality teachings, dharma based longevity strategy, astral body leaving techniques, yogic alchemy and transformation, sacred geometry meditation, pranic channel activation, ceremonial plant medicine use, trauma release breathwork, nervous system coherence chanting, biohacking consciousness optimization, mitochondrial and prana synergy Thank you to our sponsors! -Generation Lab | Go to http://generationlab.com/ , use code Dave20 for $20 off, and see what your body’s really doing behind the surface. -Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. -BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 to save 20% off your first order of PerfectAmino. Resources: • Ishan’s Website: https://ishanshivanand.com/ • Ishan’s Book ‘The Practice of Immortality’ : https://practiceofimmortality.com/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:25 — Meditation Training 4:12 — Chanting and Mantras 8:09 — Jesus in India 10:50 — Coffee and Consciousness 14:54 — Unity of Religions 19:57 — Visualization Practice 22:57 — Gold Symbolism 26:01 — Alchemy and Transformation 28:45 — Psychedelics as Medicine 31:42 — Technology and States 37:43 — Choosing Death 39:12 — Death and Consciousness 43:31 — Dharma and Immortality 45:18 — Art of Dying 51:00 — Longevity and Meditation See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 24

Here’s the hidden story behind why you can chug “pure” water all day and still feel foggy, drained, and oddly thirsty: most of what we drink is missing something essential. In this video you’ll learn what “dead water” really is, how to tell if yours is part of the problem, and the simple shifts that keep your brain sharp, energy steady, and cells fully charged—without gimmicks, hype, or drinking a gallon a day. Chapters: 00:00 – The “dead water” problem 00:23 – Why minerals matter for your brain, heart & energy 01:07 – 5,000 hydration scans: what the data shows 01:33 – The 8-glasses myth (and who benefited) 03:11 – Bottled water marketing vs reality 04:17 – Tap water: safe ≠ complete 06:00 – Hyponatremia: when “more water” backfires 07:05 – Electrolytes your cells run on 07:56 – What to do: filters, mineralizing, simple add-ins 09:03 – Timing hydration + daily micro-habits Connect with Dave Asprey! Thank you to our sponsors! -LYMA | Go to https://lyma.sjv.io/gOQ545 and use code DAVE10 for 10% off the LYMA Laser. -Vibrant Blue Oils | Grab a full-size bottle for over 50% off at https://vibrantblueoils.com/dave. Website: https://daveasprey.com TikTok: https://www.tiktok.com/@daveaspreyofficial Instagram: https://www.instagram.com/dave.asprey/ Facebook: https://www.facebook.com/Daveaspreyofficial/ X: https://x.com/daveasprey YouTube: https://www.youtube.com/c/daveaspreybpr The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/ Danger Coffee: https://dangercoffee.com/DAVE15 Dave Asprey’s BEYOND Conference: https://beyondconference.com/ Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15 Upgrade Collective: https://www.ourupgradecollective.com Upgrade Labs: https://upgradelabs.com 40 Years of Zen: https://40yearsofzen.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 21

This episode covers: • Nano CBD Pain Relief Without Cognitive Side Effects A new nano-micelle formulation of CBD called CBD-IN delivers fast, non-addictive pain relief in mice without memory issues, motor impairment or the usual cannabinoid “fog.” Because it crosses the blood brain barrier and directly targets hyperactive pain circuits, it sidesteps many opioid-type drawbacks. Dave explains why precision-designed cannabinoids could reshape chronic pain treatment and longevity support. Source: https://www.sciencedaily.com/releases/2025/11/251117095652.htm • Moderate Calorie Restriction Slows Biological Aging A long-term trial from the National Institute on Aging found that cutting calories by about 12% over two years slowed the pace of aging — measured by methylation clocks and metabolic markers — in lean and mildly overweight adults alike. Dave breaks down why small, manageable dietary tweaks can deliver big longevity gains, without crash dieting or extreme fasting. Source: https://www.nia.nih.gov/news/cutting-calories-may-slow-pace-aging-healthy-adults • FDA Approves AI-Guided Robotic Surgery Trials for Alzheimer’s The U.S. Food and Drug Administration (FDA) has granted IDE approval for the first robotic microsurgical study targeting early stage Alzheimer’s disease using AI and deep imaging. The trial uses adaptive robotics to target deep brain lymphatic pathways, potentially clearing amyloid/tau deposits with surgical precision. Dave explains why this signals a new era in neurodegeneration – moving from drug-only to machine-assisted brain repair. Source: https://www.mmimicro.com/ide-approval-for-first-robotic-microsurgery-alzheimers-study/ • Antibiotic Reprograms Gut Bacteria to Produce Anti-Aging Molecules Researchers demonstrated that the veterinary antibiotic cephaloridine can reprogram gut microbes to secrete colanic acid — a molecule linked to better mitochondrial health, reduced gut permeability and improved cholesterol/insulin balance in mice. Dave explores how this could evolve into a pipeline of engineered probiotics that act as internal “longevity factories.” Source: https://newatlas.com/aging/antibiotic-longevity-microbiome/ (link remains unchanged) • Klotho: The Longevity Protein Nears Clinical Reality The longevity protein Klotho, known for clearing toxic by-products, calming inflammation and protecting brain/organ networks, is now advancing toward human trials via injectables, oral formats and gene therapy. Dave explains why Klotho is shaping up as a foundational target for next-gen age-reversal strategies and stacking protocols. Source: https://investingnews.com/longevity-focused-health-fueling-u-s-anti-aging-products-market-projected-to-reach-27-billion-by-2033/ (link remains unchanged) All source links provided for easy reference to the original reporting and research above. This episode is essential listening for fans of biohacking, human performance, functional medicine and longevity who want practical tools from Host ­Dave Asprey and the latest breakthroughs shaping the future of health. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade gives you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence and conscious living. New episodes are released every Tuesday, Thursday, Friday (audio only) and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: nano CBD, CBD-IN, pain relief research, non opioid pain therapies, chronic pain and aging, caloric restriction aging, methylation clocks, metabolic resilience, AI robotics, Alzheimer’s microsurgery, neurotech advancement, microbiome engineering, colanic acid, longevity probiotics, mitochondrial support, Klotho protein, anti aging gene therapy, cellular rejuvenation, longevity news, biohacking updates Thank you to our sponsors! LYMA | Go to https://lyma.sjv.io/gOQ545 and use code DAVE10 for 10% off the LYMA Laser. Vibrant Blue Oils | Grab a full-size bottle for over 50% off at https://vibrantblueoils.com/dave . Resources: • Subscribe to my weekly newsletter: https://substack.daveasprey.com/welcome • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Intro 0:19 — Story 1: Nano CBD for Pain Relief 1:53 — Story 2: Caloric Restriction and Aging 3:20 — Story 3: AI Robotic Surgery for Alzheimer’s 4:50 — Story 4: Microbiome Reprogramming 6:05 — Substack Announcement 7:04 — Story 5: Klotho Longevity Protein 8:39 — Weekly Homework 9:31 — Outro See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 20

Methylene blue is one of the most misunderstood compounds in biohacking, yet it can upgrade your energy, mood, memory, and cellular resilience when you use it the right way. We are back again with another solo masterclass, and this one breaks down how to use methylene blue as a precision tool for brain optimization, longevity, and human performance while avoiding the dosing mistakes that create jitteriness, sleep disruption, or dangerous interactions. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey guides you through more than a century of research on methylene blue. He has been hacking this compound since the early 2000s and brings deep insight into mitochondria, neuroplasticity, metabolism, supplements, fasting, red light, ketosis, nootropics, and functional medicine. You will learn how methylene blue works inside the cell, how it improves electron transport, and why it appears in neurology, psychiatry, and anti aging research at the same time. This episode shows you how to test your own dose, how to stack it with light and ketosis for maximum effect, and how to avoid serotonin syndrome or sleep disruption. Methylene blue also touches nearly every major system that biohackers care about, which is why this solo masterclass shows you how it interacts with mitochondria, neuroplasticity, metabolism, sleep optimization, and long term anti aging pathways. You will hear how it influences redox balance, ATP production, brain optimization, and stress resilience, and how it behaves when combined with ketosis, fasting, creatine, NAD boosters, red light therapy, or other nootropics. Host Dave Asprey explains why methylene blue pairs well with certain supplements but clashes with psychedelics or SSRI medications, how it fits into functional medicine protocols for mitochondrial repair, and how to use data and wearable tracking to dial in your response. This episode gives you a complete framework to evaluate whether methylene blue belongs in your personal longevity strategy and how to use it with precision instead of guesswork. You’ll Learn: • Why methylene blue acts like mitochondrial jumper cables and when it improves energy and mood • The exact signs that your dose is too strong, too weak, or in the Goldilocks zone • How methylene blue interacts with neuroplasticity, memory circuits, and cognitive resilience • Why psychedelics, SSRIs, and MAO inhibitors can create dangerous serotonin interactions • How to pair methylene blue with red light therapy, ketosis, creatine, fasting, or NAD boosters • The link between mitochondrial health, fertility, libido, and long term anti aging strategies • How to track sleep optimization, HRV, and performance signals to dial in your personal protocol • The difference between aquarium grade dye and pharmaceutical grade formulations • Why genetic testing for G6PD deficiency is essential before higher dose experimentation Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee , and the father of biohacking . With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS) . Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: methylene blue dosing, mitochondrial electron transport, Complex IV cytochrome c oxidase, redox cycling, MAO inhibition, serotonin syndrome risk, G6PD deficiency caution, neuroplasticity enhancement, dendritic spine density, mitochondrial stress adaptation, red light therapy stacking, cognitive performance optimization, ketone supported ATP production, nitric oxide independent focus boost, mitochondrial bottleneck repair, pharmaceutical grade methylene blue, sleep disruption signals, biohacking fertility support, oxidative stress buffering, functional medicine mitochondria repair Thank you to our sponsors! -BrainTap | Go to http://braintap.com/dave to get $100 off the BrainTap Power Bundle. -fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. -Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Resources: • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:25 — Introduction 4:51 — History of methylene blue 7:38 — How methylene blue works 14:05 — Safety 17:53 — Dosing and timing guidelines 20:41 — Combining with red light therapy 22:41 — Quality and sourcing 23:17 — Dosing protocols 25:24 — Longevity and fertility effects 29:24 — Stacking options 32:10 — Common questions and FAQs 33:40 — Future research and wrap up See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 18

Bioelectronic medicine is changing how we treat inflammation, autoimmunity, and chronic disease, and this episode shows you exactly how nerve stimulation could redefine human performance, longevity, and brain optimization. You will learn how electricity, neurotransmitters, and targeted neural pathways can replace drugs, control inflammation, and help you hack the vagus nerve with precision instead of guesswork. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey is joined by Kevin J. Tracey, MD, president and CEO of the Feinstein Institutes for Medical Research at Northwell Health, pioneer of vagus nerve research, and author of The Great Nerve. He is one of the world’s most cited scientists in inflammation and neuroscience, and his discoveries created the field now known as bioelectronic medicine. He identified the therapeutic action of anti TNF antibodies, mapped the inflammatory reflex, and revealed how vagus nerve signaling controls immunity. With more than 450 scientific publications and over 120 U.S. patents, he is a trusted authority whose work drives the future of anti-aging, functional medicine, metabolism, and neural therapies. Dr. Tracey and Host Dave Asprey explore how the vagus nerve truly operates, why it contains 200,000 fibers with different functions, and what happens when you stimulate specific pathways that regulate inflammation, HRV, neurotransmitters, and immune signaling. You will learn how nerve impulses transmit information, how voltage gated ion channels shape behavior and biology, and why certain forms of stimulation create measurable improvements in mitochondria, metabolic control, sleep optimization, and emotional regulation. They break down the science behind surgical vagus nerve implants, focused ultrasound, gamma entrainment, cytokine control, and real neuromodulation. They also explore why cold plunging, breath work, HRV training, nootropics, and consumer devices vary so widely in their effects, and how to evaluate these tools with practical biohacking frameworks. You will hear what actually works, what remains experimental, and what the next decade of nerve based therapies could unlock for brain optimization, longevity, ketosis, fasting, supplements, and AI guided interventions in human biology. You’ll Learn: • How vagus nerve stimulation reduces inflammation through the inflammatory reflex • Why bioelectronic medicine can replace drugs in autoimmune conditions • How nerve fibers relay electrical and chemical signals inside the body • Why cold immersion, breath work, and HRV training activate specific vagal pathways • How 40 hertz gamma entrainment may influence cognitive decline • Which stimulation methods have clinical validation and which do not • Why high vagal tone is linked to better metabolism, immunity, and emotional stability • What future nerve based technologies may unlock for human performance Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee , and the father of biohacking . With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS) . Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Kevin J. Tracey, vagus nerve stimulation, bioelectronic medicine, inflammatory reflex, SetPoint Medical, cytokine control, neuromodulation therapy, autonomic nervous system, HRV optimization, inflammation reduction, rheumatoid arthritis treatment, focused ultrasound therapy, gamma entrainment, mitochondrial signaling, anti-aging science, neural pathway hacking, functional medicine research, immune system regulation, brain and body performance, human longevity science Thank you to our sponsors! -AquaTru | Go to https://aquatruwater.com/daveasprey and save $100 on all AquaTru water purifiers. -MASA Chips | Go to https://www.masachips.com/DAVEASPREY and use code DAVEASPREY for 25% off your first order. -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. -Calroy | Head to https://calroy.com/dave for an exclusive discount Resources: • Learn More About Kevin’s Work: https://feinstein.northwell.edu/institutes-researchers/our-researchers/kevin-j-tracey-md • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 - Trailer 1:12 - Bioelectronic Medicine 3:23 - FDA Approval 6:48 - RA Treatment Explained 11:35 - Vagus Nerve Function 15:12 - External vs Implanted Stimulation 18:06 - Focused Ultrasound 26:11 - Ear Stimulation Science 30:51 - Clinical Evidence 37:10 - Alzheimer’s Link 42:15 - Future Applications 46:48 - Cold Exposure Effects 53:51 - Common Misconceptions 55:38 - Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 16

What if the secret to living longer wasn't locked in a lab, but hiding in plain sight? And what could lobsters possibly teach us about staying young? Scientists have discovered a remarkable connection between an ancient practice and our cellular aging process - one that celebrities and longevity researchers are quietly using to their advantage. It involves an enzyme in your body that most people don't even know exists, yet it plays a crucial role in how fast (or slow) you age. The twist? You can activate it in just 10 minutes a day, no prescription required. Curious about the biological "switch" that might help you turn back your cellular clock? The answer might surprise you... *Chapters* 0:00 – Introduction 0:46 – Lobsters and Human Longevity Connection 1:14 – Understanding Telomeres and Aging 2:26 – How Lobsters Defy Aging 3:32 – Rethinking Aging Biology 4:53 – The Telomerase Challenge 6:43 – Natural Ways to Protect Telomeres 9:33 – Meditation's Role in Anti-Aging 11:04 – Different Meditation Techniques 13:19 – Benefits and Long-Term Effects Resources: • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com ADS/SPONSORS BodyGuardz | Visit https://www.bodyguardz.com/ and use code DAVE for 25% off. AirDoctor | Go to https://airdoctorpro.com/daveasprey and save up to $300 on Air Purifiers. Connect with Dave Asprey! Website: https://daveasprey.com TikTok: https://www.tiktok.com/@daveaspreyofficial Instagram: https://www.instagram.com/dave.asprey/ Facebook: https://www.facebook.com/Daveaspreyofficial/ X: https://x.com/daveasprey YouTube: https://www.youtube.com/c/daveaspreybpr The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 14

This episode covers: • Cocoa Extract Cuts Heart Deaths A massive COSMOS trial found that older adults taking high flavanol cocoa extract daily saw a 27 percent reduction in cardiovascular deaths along with drops in inflammation markers like HSCRP. Women showed unique anti inflammatory cytokine shifts, pointing to a broader longevity effect. Dave explains why cocoa extract is becoming a foundational nutrient for vascular health rather than a dessert ingredient. Source: https://www.sciencedaily.com/releases/2025/09/250926135957.htm • AI Stethoscope for Home Diagnostics Lapsi Health’s Keikku 2.0 just became the first FDA cleared AI powered digital stethoscope for both clinicians and home users. It records heart and lung sounds, analyzes them instantly, and flags early warning signs before symptoms appear. Dave breaks down why tools like this move you from reactive to predictive medicine and why they belong in every quantified self toolkit. Source: https://www.prnewswire.com/news-releases/lapsi-health-unveils-keikku-2-0-worlds-first-fda-cleared-digital-stethoscope-with-integrated-ai-scribe-302585083.html?utm_source=chatgpt.com • Beef Organ Supplements Surge Beef organ supplements have exploded more than 8,000 percent this year, driven largely by women reporting improvements in energy, hormones, mood, and skin. Liver, kidney, and heart deliver vitamin A, heme iron, B12, copper, and choline that modern diets often lack. Dave covers sourcing concerns, purity standards, and why this shift reflects a move from fear based nutrition to evolutionary nutrition. Source: https://www.verywellhealth.com/beef-organ-supplement-11710185?utm_source=chatgpt.com • Spirulina for Collagen and DNA Protection New research highlights spirulina’s ability to support collagen production, reduce oxidative stress, protect DNA, and improve glucose and lipid balance. It is becoming a staple of eco focused anti aging routines and is driving the viral green stacking trend with chlorella and chlorophyll. Dave explains why spirulina functions as a clean daily defense against oxidative stress. Source: https://www.news-medical.net/news/20250707/Is-Spirulina-the-Next-Anti-Aging-Superfood.aspx • Health Data Privacy Reform A new Senate bill aims to extend HIPAA level protections to wearables, genomic tools, glucose monitors, and wellness apps. The goal is to give users control over who sees their biometrics, how they are stored, and whether they can be sold. Dave outlines why this matters for anyone using Oura, Whoop, CGMs, or genetic testing and why your biology should belong to you and not the cloud. Source: https://natlawreview.com/article/federal-healthcare-update-november-7-2025 All source links provided for easy reference to the original reporting and research above. This is essential listening for fans of biohacking, hacking human performance, functional medicine, and longevity who want actionable tools from Host Dave Asprey and a guest who embodies what it means to age with energy, clarity, and vitality. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday (audio-only), and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: cocoa extract, flavanols, heart health, nitric oxide pathways, COSMOS trial, AI stethoscope, digital diagnostics, Keikku device, predictive health tech, beef organ supplements, women’s hormonal health, nutrient dense foods, ancestral nutrition, spirulina benefits, collagen support, oxidative stress defense, green stacking, chlorella pairing, DNA protection, wearable privacy laws, HIPAA reform, biometric data rights, longevity news, biohacking updates Thank you to our sponsors! Essentia | Go to https://myessentia.com/dave and use code DAVE for $100 off The Dave Asprey Upgrade. ECHO Water | Go to http://echowater.com/dave and use code DAVE10 for 10% off your ECHO Flask. Resources: • Subscribe to my weekly newsletter: https://substack.daveasprey.com/welcome • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 – Intro 0:19 – Cocoa Extract & Heart Health 1:52 – AI Digital Stethoscope 3:01 – Beef Organ Supplements 4:24 – Spirulina for Longevity 5:42 – Substack Announcement 6:53 – Health Data Privacy Reform 8:23 – Weekly Upgrade Protocol 9:46 – Outro See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 13

Your workouts may be doing less than you think, and science now proves why. This episode reveals how to build muscle, improve metabolism, and extend longevity in a fraction of the time using blood flow restriction training and intermittent hypoxia. You’ll learn how to hack your mitochondria for faster recovery, stronger hormonal balance, and better brain performance without the burnout of high-intensity training. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey talks with Dr. Sten Stray-Gundersen , PhD, CSCS, one of the world’s leading experts on blood flow restriction (BFR) training and metabolic physiology. With over a decade of research and teaching experience, Dr. Stray-Gundersen has explored how BFR and intermittent hypoxia can improve cardiovascular health, metabolism, and recovery. After earning his doctorate in Exercise Physiology from the University of Texas at Austin, he now serves as an Assistant Professor at the University of South Carolina, where he studies vascular adaptations, cognitive performance, and ergogenic aids. He’s also a B Strong master trainer, developing individualized BFR protocols for athletes, military professionals, and everyday people looking to optimize human performance. Together, Dave and Sten uncover how BFR and oxygen cycling unlock powerful adaptations in the body’s vascular, metabolic, and hormonal systems. You’ll learn how strategic stress signals can trigger nitric oxide production, enhance glucose uptake, improve insulin sensitivity, and supercharge mitochondria for better energy and anti-aging benefits. They also explore how these methods can naturally boost testosterone, growth hormone, and even libido, all while protecting the nervous system and improving recovery. This episode dives deep into biohacking, functional medicine, and smart exercise efficiency, from Zone 2 and REHIT training to nitric oxide signaling, fasting, nootropics, and precision supplementation. Whether your goal is longevity, strength, or sharper cognition, this conversation shows you how to get maximum results with minimal time using the principles of Smarter Not Harder. You’ll Learn: • How intermittent hypoxia works at the level of partial pressure and why altitude acclimation upgrades mitochondria and performance • Why hypoxia and muscle contraction increase glucose uptake independent of insulin and improve insulin sensitivity • How blood flow restriction (BFR) accelerates fatigue with light loads to drive hypertrophy, strength, and vascular adaptations • How BFR and hypoxia influence testosterone, growth hormone, nitric oxide, and libido through short, targeted stress • The roles of ENOS, INOS, and NNOS in nitric oxide signaling and what that means for circulation and brain perfusion • Who benefits most from BFR, including athletes, rehab patients, and older adults who cannot lift heavy • Why BFR produces systemic and “proximal” gains, including carryover to glutes and upper body during lower limb training • How to stack BFR with Zone 2, REHIT, and vibration plates for VO2 max, muscle, and time efficiency Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee , and the father of biohacking . With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS) . Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Sten Stray-Gundersen, blood flow restriction training, B Strong, intermittent hypoxia, mitochondrial function, nitric oxide production, VO2 max, metabolic efficiency, vascular health, testosterone boost, growth hormone release, anti-aging performance, exercise recovery, glucose metabolism, functional medicine, biohacking fitness, REHIT training, Zone 2 optimization, strength and longevity, human performance science Thank you to our sponsors! -KILLSwitch | If you’re ready for the best sleep of your life, order now at https://www.switchsupplements.com/ and use code DAVE for 20% off. -EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE for 40% off. -Leela Quantum Tech | Check out all HEAL360 products and research and get 10% off at https://leelaq.com/DAVE . -ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. Resources: • Use code DAVE10 to get a discount on a BFR band today: https://shopify.bstrong.training/products/b-strong-training-system?ref=dave%2F • Dive deeper in Sten’s work at: https://bstrong.training/ • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 - Trailer 1:25 - Guest Intro 5:40 - Intermittent Hypoxia & Altitude Acclimation 12:11 - Introduction to Blood Flow Restriction (BFR) 22:53 - Systemic Benefits & Who Can Use BFR 30:23 - BFR Effects on Hormones & Libido 40:37 - Nitric Oxide & Vascular Health 48:15 - Zone 2 Training with BFR 54:00 - Advanced Protocols: Stacking BFR 59:15 - Cognitive Enhancement & Wrap-Up See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 11

True transformation doesn’t come from motivation. It comes from rewiring your mind, reshaping your beliefs, and mastering your perception of reality. This episode reveals how to stop chasing short bursts of inspiration and start creating sustainable change in your thoughts, energy, and biology. You’ll learn how belief, emotion, and neuroplasticity shape human performance, longevity, and resilience—and how to reprogram them for lasting results. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with David Bayer , one of the greatest personal growth teachers of our time. His podcast A Changed Mind reaches over 1 million listeners each month, and his event Powerful Living Experience Live was named a top 3 personal development event by Inc. Magazine . His book A Changed Mind has transformed tens of thousands of lives. David blends behavioral psychology, neuroscience, metaphysics, and consciousness theory into practical frameworks that help people rewire their brains and reengineer their reality. He is an entrepreneur, business strategist, keynote speaker, and mentor to some of the world’s most influential entrepreneurs and creators. Together, Dave and David explore how motivation is just a microdose of transformation and why true change requires aligning your perception with how reality actually works. They break down the science behind belief, energy, and consciousness, connecting these ideas with biohacking, supplements, functional medicine, and brain optimization. You’ll Learn: • Why motivation is only a temporary fuel and how to create lasting transformation • How to test your beliefs against reality and rewire the mind through awareness • The difference between absolute truth and personal truth in consciousness work • Why suffering and challenge are essential for growth and resilience • How to build faith as a biological and psychological muscle • How early trauma programs limiting beliefs and emotional patterns • The four layers of resistance that block personal transformation • Why forgiveness and self-love are essential to dissolving trauma • How perception literally shapes your experience of reality • Practical tools to align your consciousness for high performance and peace Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee , and the father of biohacking . With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS) . Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: David Bayer, A Changed Mind, Powerful Living Experience, belief systems, consciousness theory, neuroscience, behavioral psychology, personal growth, trauma transformation, resilience training, perception shift, motivation vs transformation, emotional regulation, mindset reprogramming, subconscious rewiring, neurohacking, cognitive performance, spiritual psychology, reengineering reality, high-performance mindset, sustainable change Thank you to our sponsors! -GOT MOLD? | Go to http://gotmold.com/shop and use DAVE10 to save 10% and see what’s in your air. -Generation Lab | Go to http://generationlab.com/ , use code Dave20 for $20 off, and see what your body’s really doing behind the surface. -Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. -LMNT | Get a free 8-count Sample Pack of LMNT with any drink mix purchase by going to https://drinklmnt.com/DAVE . Resources: • Learn more about David’s work: www.davidbayer.com • Order David’s book: https://www.amazon.com/Changed-Mind-Beyond-Awareness-Extraordinary/dp/1642939862 • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 - Trailer 1:25 - Why Motivation Isn’t Sustainable 5:14 - Testing Reality as a Hypothesis 9:02 - Absolute Truth vs Personal Truth 11:02 - The Role of Suffering in Growth 15:01 - Building Faith as a Muscle 18:27 - Higher Power & Placebo Effect 20:38 - Believing Without Limits 24:27 - Transforming Childhood Trauma 27:34 - The Four Layers of Resistance 28:58 - Resentment & Forgiveness 33:09 - Turn the Other Cheek 39:28 - Entrepreneurs & Self-Sabotage 43:59 - Building Resilience in Business 46:00 - Closing Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 9

Discover a little-known Japanese walking technique that outperforms 10,000 steps a day. It boosts fat burning, lowers stress, improves mitochondria, and transforms your metabolism—all in just 15–30 minutes. Perfect for anyone who wants sustainable results without punishment workouts. *Chapters* 00:00 – 00:46 My 300 lb journey & the surprising Japanese method 00:46 – 01:54 Why mainstream fitness advice fails for fat loss 01:54 – 02:37 Walking as the most underrated fat-burning tool 02:37 – 04:03 The problem with steps & the Japanese breakthrough 04:03 – 05:52 How interval walking works & how to do it 05:52 – 09:12 Outdoor hacks that maximize results Connect with Dave Asprey! Website: https://daveasprey.com TikTok: https://www.tiktok.com/@daveaspreyofficial Instagram: https://www.instagram.com/dave.asprey/ Facebook: https://www.facebook.com/Daveaspreyofficial/ X: https://x.com/daveasprey YouTube: https://www.youtube.com/c/daveaspreybpr The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/ Resources: • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 7

Upgrade your biology in 10 minutes with this week’s rundown from Dave Asprey. This episode breaks down the six biggest stories in biohacking and health tech, from sleep hormones to mitochondrial rejuvenation, giving you the data you need to live longer, think faster, and perform at your peak. This episode covers: • The Melatonin Heart Warning Everyone Missed A major new study from the American Heart Association reveals that long-term melatonin users face nearly twice the risk of heart failure and 3.5 times higher hospitalization rates. Once considered a harmless sleep aid, melatonin’s hormonal effects may disrupt cardiovascular recovery, testosterone, and blood pressure regulation when used nightly. The takeaway: melatonin is a short-term circadian reset tool, not a forever supplement. Source: American Heart Association — newsroom.heart.org/news/long-term-use-of-melatonin-supplements-to-support-sleep-may-have-negative-health-effects • Bryan Johnson’s Extreme Microplastics Detox Biohacker Bryan Johnson shared lab-verified results showing an 85% reduction in microplastics in his semen after one year of daily 200°F dry saunas followed by ice packs on the groin. It’s not peer reviewed yet, but it’ssparking global discussion about environmental toxins, fertility, and detoxification. Whether or not you follow his protocol, this study highlights how widespread microplastics have become and how heat, sweat, and smarter exposure control may help fight back. Source: New York Post — nypost.com/2025/10/23/health/biohacker-bryan-johnson-got-rid-of-85-of-microplastics-from-his-semen • Urolithin A: The Mitochondrial Molecule That Strengthens Immunity A peer-reviewed human trial published in Nature Aging found that four weeks of daily Urolithin A (Mitopure®) supplementation improved immune function in adults aged 45–70, increasing youthful CD8 T-cells, natural killer cells, and mitochondrial performance inside immune cells. By triggering mitophagy, your body’s cleanup process for old mitochondria, Urolithin A enhances energy, resilience, and immune strength. It’s the clearest evidence yet that we can modulate immune aging through mitochondrial renewal. Head to timeline.com/dave to get 10% off your first order. Source: BioSpace — biospace.com/press-releases/timeline-continues-to-build-the-most-clinically-researched-longevity-products-targeting-immune-brain-and-muscle-aging • Google’s New AI Model That “Talks” to Cells Google DeepMind and Yale launched Cell2Sentence-Scale , an open-source AI model that lets scientists query cellular pathways in natural language. The system can predict how cells transition from healthy to cancerous states and identify molecular switches that might reverse those changes. It’s compressing years of biology into days and democratizing research for small labs and independent scientists alike. Isn’t AI a beautiful thing? Source: Google DeepMind — blog.google/technology/ai/google-gemma-ai-cancer-therapy-discovery • Omega-3s Calm the Brain and the Temper A massive new meta-analysis of randomized controlled trials shows omega-3 fatty acids (EPA and DHA) reduce aggression by up to 28%. That includes both reactive anger and planned aggression. By lowering neuroinflammation and stabilizing cell membranes, omega-3s appear to balance dopamine and serotonin, proving that healthy fats aren’t just heart food, they’re emotional regulators too. Source: Science Alert — sciencealert.com/one-dietary-supplement-was-shown-to-reduce-aggression-by-up-to-28 • Chronic Fatigue Syndrome Finally Gets a Biomarker For the first time, researchers have developed a blood test that accurately identifies chronic fatigue syndrome (ME/CFS) using DNA methylation and micro-RNA expression patterns. This breakthrough distinguishes CFS from other autoimmune and viral conditions, marking a turning point for millions of patients long dismissed by traditional medicine. It’s proof that data-driven diagnostics can transform how we understand mystery illnesses. Source: Science Daily — sciencedaily.com/releases/2025/11/251102205021.htm All source links provided for easy reference to the original reporting and research above. This is essential listening for fans of biohacking, hacking human performance, functional medicine, and longevity who want actionable tools from Host Dave Asprey and a guest who embodies what it means to age with energy, clarity, and vitality. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: melatonin heart risk, sleep hormones, microplastics detox, Bryan Johnson, Urolithin A, mitophagy, mitochondrial health, immune aging, DeepMind AI, cellular modeling, omega-3 aggression, neuroinflammation, chronic fatigue biomarker, ME/CFS test, biohacking news, longevity research Thank you to our sponsors! -LYMA | Go to https://lyma.sjv.io/gOQ545 and use code DAVE10 for 10% off the LYMA Laser. -Vibrant Blue Oils | Grab a full-size bottle for over 50% off at https://vibrantblueoils.com/dave . Resources: • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Intro 0:18 — Story 1: Melatonin & Heart Health 1:58 — Story 2: Microplastics Detox 3:39 — Story 3: Urolithin A & Immune Function 5:19 — Story 4: AI Cell Model 6:57 — Story 5: Omega-3 & Aggression 8:43 — Story 6: CFS Blood Test 9:59 — Weekly Upgrade Protocol See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 6

Pain isn’t just in your body, it’s in your brain. In this groundbreaking episode, Host Dave Asprey sits down with Dr. Daniel Amen to reveal how emotional and physical pain share the same neural circuits and how you can rewire them for relief, resilience, and longevity. You’ll learn practical tools to break the “doom loop” of pain, restore neuroplasticity, and retrain your brain for calm, healing, and high performance. This is essentiallistening for anyone ready to stop managing pain and start hacking it. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR The Washington Post called Dr. Daniel Amen the most popular psychiatrist in America. He is a former infantry medic and board certified child and adult psychiatrist who trained at the Walter Reed Army Medical Center in Washington, DC. He is the CEO and founder of Amen Clinics, with 11 locations nationwide and home to the world’s largest brain imaging database for psychiatry with nearly 300,000 SPECT scans on patients from 155 countries. Dr. Amen is a 12 time New York Times bestselling author, including the books Change Your Brain, Change Your Life , Healing ADD , Memory Rescue , Raising Mentally Strong Kids , and The End of Mental Illness . He has published over 90 scientific articles and led groundbreaking brain imaging research on NFL players, childhood trauma, negativity bias, reversing brain aging, obesity and the brain, and predicting treatment responses. With over 10 million followers and multiple PBS specials, his mission is bold: to end mental illness by creating a revolution in brain health. His newest book Change Your Brain, Change Your Pain explores the neuroscience of pain and how to heal it through brain optimization and functional medicine. Host Dave Asprey and Dr. Amen uncover how suppressed emotions, inflammation, gut health, and mitochondrial function all influence pain and what you can do to reverse it using biohacking, functional medicine, and supplements. They explore how chronic pain rewires neural pathways, how to activate your brain’s natural calming switch, and why techniques like hypnosis, red light therapy, rage journaling, and havening can restore balance to your nervous system. You’ll also learn the surprising links between aspartame, Tylenol, and generational anxiety, and how to protect your mitochondria to optimize energy, metabolism, and emotional resilience. This episode delivers practical, science based tools for brain optimization, sleep optimization, neuroplasticity, and anti aging while connecting the dots between biohacking, psychology, and functional medicine to help you live smarter not harder. You’ll Learn: • How emotional pain and physical pain run on the same brain circuits • Why suppressed rage can trigger chronic pain and how to release it • The link between inflammation, gut health, and brain suffering pathways • How supplements like saffron, curcumin, and omega 3s support pain relief and mood • Why red light therapy, hypnosis, and havening boost neuroplasticity and calm the nervous system • How environmental toxins, aspartame, and Tylenol disrupt mitochondria and increase pain • Simple daily habits to retrain your brain for resilience, optimism, and longevity Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee , and the father of biohacking . With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS) . Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: chronic pain neuroscience, emotional pain circuits, Change Your Brain Change Your Pain, Dr. Daniel Amen, Dave Asprey, biohacking, neuroinflammation, anterior cingulate cortex, SPECT imaging, mitochondrial metabolism, functional psychiatry, neuroplasticity, rage therapy, havening technique, red light therapy, saffron supplements, aspartame toxicity, gut brain axis, trauma healing, pain hacking BrainMD Happy Saffron Plus: Order Your Saffron Plus Here: https://www.awin1.com/cread.php?awinmid=89351&awinaffid=855302&ued=https%3A%2F%2Fbrainmd.co… Use Dave’s 15% OFF Discount Code: DAVE15 Please note – works on one-time purchases or the first order of a subscription . Thank you to our sponsors! • NeuroVeda Health | Go to https://www.neurovedahealth.com/asprey to learn more and book your week. • AquaTru | Go to https://aquatruwater.com/daveasprey and save $100 on all AquaTru water purifiers. • BON CHARGE | Go to https://boncharge.com and use code DAVE for 15% off. • ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. Dave's Resources: • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 00:00 — Trailer 01:25 — Dr. Amen’s Brain Scan Research 02:11 — Physical vs Emotional Pain 05:15 — Childhood Trauma and Pain 08:10 — The Doom Loop Explained 14:01 — Havening Technique 18:27 — Training Positivity and Hope 22:11 — Rage Therapy and Journaling 26:44 — COVID and Brain Inflammation 29:41 — Mitochondria and Energy 36:14 — Pain Relief Protocol 39:32 — Saffron for Pain 43:28 — Aspartame and Anxiety 47:30 — Pain Switches in the Brain 50:50 — Red Light Therapy 52:39 — Fear and Pain Loops 56:36 — Environmental Toxins 58:21 — Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 4

Your body does not just run on food or supplements. It runs on energy and information. This episode reveals how to harness that energy for faster recovery, stronger mitochondria, and better emotional resilience. You will learn how energy fields, frequency, and information medicine are reshaping the science of human performance, longevity, and anti-aging. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Harry Massey , a British entrepreneur, filmmaker, and visionary in the field of bioenergetics. In his 20s, Harry’s health collapsed after a series of physical injuries, viral infections, and emotional trauma left him bedridden for seven years with chronic fatigue syndrome. Conventional medicine could not provide answers, so Harry began studying energy and information as the missing foundations of human health. His discovery of the pioneering research of Australian scientist Peter Fraser led to a breakthrough. Using Fraser’s early frequency-imprinted remedies, Harry experienced a dramatic recovery and went on to co-found NES Health , now Energy4Life , to bring this new field of bioenergetics to the world. Backed by published studies at UC San Diego showing a 22 percent increase in mitochondrial efficiency and the activation of more than 1,000 genes for cell resilience, Harry’s work unites ancient healing wisdom with modern physics, light therapy, and quantum biology. Together, Dave and Harry explore how bioenergetics, light frequencies, and digital information enhance neuroplasticity, metabolism, and sleep optimization more effectively than supplements or nootropics alone. You will discover how trauma drains energy, how to restore it through the body’s natural field communication systems, and how wearable tech and AI are transforming functional medicine. You’ll Learn: • How bioenergetic wearables increase mitochondrial energy by 22 percent • Why emotional trauma and energy leaks accelerate aging • How structured water and light frequencies store biological information • The connection between quantum biology, neuroplasticity, and healing • How energy fields regulate longevity, metabolism, and brain optimization • Why AI-powered diagnostics and frequency medicine are the next frontier in biohacking Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee , and the father of biohacking . With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS) . Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: energy healing, bioenergetics, Harry Massey, Dave Asprey, Energy4Life, NES Health, Infoceuticals, GEM wearable, frequency medicine, energy field, quantum biology, mitochondria, neuroplasticity, functional medicine, human performance, longevity, sleep optimization, anti-aging, metabolism, trauma healing, brain optimization, light therapy, structured water, information medicine, UCSD study, Peter Fraser, energy medicine, energy hacking, biohacking, nootropics, supplements, ketosis, fasting, AI, smarter not harder, Danger Coffee **Grab a generous discount from Harry at https://e4l.com/dave ** Thank you to our sponsors! -BiOptimizers | Go to http://bioptimizers.com/dave and use code DAVE15 to get 15% off your order. -AirDoctor | Go to https://airdoctorpro.com/daveasprey and save up to $300 on Air Purifiers. -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. -Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Resources: • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 – Trailer 1:25 – Seven Years Bedridden 3:50 – Three Traumatic Events at 21 6:43 – Searching for Answers 9:02 – Meeting Peter Fraser in LA 11:10 – Dave’s Skepticism About Homeopathy 17:42 – The GEM Wearable Device 20:29 – Mitochondrial Efficiency Research 27:05 – Body as Signaling Networks 30:49 – Challenging the Chemical Model 35:10 – Biohacking and Ancient Practices 36:15 – Future of Bioenergetics 44:40 – Closing Thoughts on Energy See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 2

What if getting older had less to do with your birthday and more to do with the health of your cells? Some people in their 50s feel stronger and sharper than ever, while others feel decades older than they are. The difference isn’t luck or expensive treatments. In this video, you’ll learn what really drives aging, how to measure it, and the surprising practices that can help you feel younger, stronger, and more focused right now. Chapters 0:00 – Introduction 0:21 – Why aging isn’t about time 0:49 – Biological age vs chronological age 1:40 – Cellular dysfunction and mitochondria 3:00 – How weak mitochondria accelerate aging 4:00 – Turning on your body’s switch 6:44 – REHIT workouts to build new mitochondria 8:45 – Fueling with fats for clean energy 10:05 – Your body’s deep clean process 13:56 – Fasting methods that support renewal 15:58 – The hidden factor: chronic stress 19:02 – Stress hacks to unlock longevityConnect with Dave Asprey! Thank you to our sponsor! -MASA Chips | Go to https://www.masachips.com/DAVEASPREY and use code DAVEASPREY for 25% off your first order. Website: https://daveasprey.com TikTok: https://www.tiktok.com/@daveaspreyofficial Instagram: https://www.instagram.com/dave.asprey/ Facebook: https://www.facebook.com/Daveaspreyofficial/ X: https://x.com/daveasprey YouTube: https://www.youtube.com/c/daveaspreybpr The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/ Danger Coffee: https://dangercoffee.com/DAVE15 Dave Asprey’s BEYOND Conference: https://beyondconference.com/ Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15 Upgrade Collective: https://www.ourupgradecollective.com Upgrade Labs: https://upgradelabs.com 40 Years of Zen: https://40yearsofzen.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 31

Discover how quantum energy, frequency medicine, and consciousness science are rewriting what’s possible for human performance and longevity. This episode reveals how your biofield, mitochondria, and brain can be trained, just like your muscles, to achieve higher focus, deeper resilience, and accelerated healing. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey talks with Philipp Samor von Holtzendorff-Fehling, founder and CEO of Leela Quantum Tech , about the cutting-edge research proving that quantum energy can neutralize EMF damage, improve neuroplasticity, and activate self-healing at the cellular level. A former telecom executive turned energy researcher, Philipp has led dozens of double-blind, placebo-controlled studies validating measurable shifts in brain waves, ATP production, blood flow, and human coherence. You’ll learn how quantum energy interacts with your nervous system, mitochondria, and electromagnetic environment to unlock higher states of consciousness and energy. Philipp and Dave dive into the science behind biofield technology, the real dangers of 5G and EMFs, and how to use frequency devices, structured water, and energetic optimization to enhance your metabolism, sleep quality, and emotional stability. You’ll Learn: • How quantum energy measurably enhances brain coherence, ATP production, and longevity • Why EMFs disrupt your mitochondria, and the proven ways to neutralize their effects • How frequency medicine and structured water improve resilience and energy levels • What double-blind studies reveal about human performance, neuroplasticity, and healing • How to integrate quantum tech with fasting, nootropics, and supplements for full-body optimization • The role of consciousness and energy fields in unlocking true anti-aging and human potential This conversation bridges biohacking and functional medicine, exploring how quantum biology complements nootropics, fasting, ketosis, and supplements to accelerate anti-aging and brain optimization. You’ll walk away with a new understanding of energy as the missing link in hacking your biology and extending your longevity. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee , and the father of biohacking . With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS) . Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: quantum energy, Leela Quantum Tech, Philipp Samor von Holtzendorff-Fehling, biohacking, EMF protection, frequency medicine, human performance, mitochondria, neuroplasticity, ATP production, brain optimization, anti-aging, functional medicine, structured water, consciousness, energy healing, nootropics, sleep optimization, longevity, quantum biology **Go to https://leelaq.com/dave for a discount on Leela Quantum!** Resources: • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:25 — Intro 7:04 — Why Quantum is Controversial 10:11 — How Quantum Healing Works 14:47 — EMF Effects on the Brain 17:35 — Living in the EMF Soup 20:55 — Elon Musk and EMF Denial 22:32 — How Leela Quantum Technology Works 26:29 — Water Optimization Research 34:54 — Charging Clothing and Objects 37:31 — Frequency Medicine Applications 42:03 — Skeptics Turned Believers 55:40 — The Energy of Everything (Book Launch) 59:05 — Quantum Upgrade Service Settings 1:02:21 — Protection from Negative Energy See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 30

Heart rate variability isn’t just a fitness metric, it’s the master signal of human performance, emotional regulation, and longevity. This episode reveals how you can use HRV to hack your nervous system, regulate stress in real time, and build true resilience from the inside out. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Rollin McCraty, Ph.D., Director of Research at the HeartMath Institute and a leading psychophysiologist exploring how the heart, brain and human consciousness are interconnected. For more than three decades his pioneering research into heart-brain communication and geomagnetic field interactions has supported the development of HRV/coherence-training tools and coherence biofeedback technology. His work has been featured in documentaries such as I Am , The Power of the Heart and The Living Matrix . Together, Dave and Dr. McCraty uncover how heart-brain coherence can improve neuroplasticity, optimize sleep, strengthen mitochondria, and create emotional stability even under extreme stress. You’ll discover how five minutes a day of coherence training can elevate focus, resilience, and connection, helping every other biohack, from fasting and ketosis to supplements and nootropics, work more effectively. You’ll Learn: • What HRV really measures and why it predicts performance and longevity • How coherence breathing balances your nervous system and sharpens cognition • Why emotional regulation begins in the heart, not the mind • How environmental and solar energy affect your physiology, and how to stay stable • The Navy-proven HRV method for better sleep and stress recovery • How coherence training outperforms traditional meditation for daily resilience • The measurable science behind “radiating love” and creating heart-based connection This is essential listening for anyone serious about biohacking, brain optimization, functional medicine, and anti-aging. Whether you’re optimizing metabolism, fine-tuning sleep, or upgrading your energy with Danger Coffee, coherence training helps you live smarter, not harder, by syncing your biology with the rhythm of life itself. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee , and the father of biohacking . With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS) . Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: heart rate variability, HRV training, HeartMath, Rollin McCraty, heart-brain coherence, biohacking, emotional regulation, nervous system, stress resilience, neuroplasticity, longevity, sleep optimization, mitochondria, functional medicine, anti-aging, coherence breathing, vagus nerve, HRV recovery, brain optimization Go to the following link for 15% off the HeartMath device: https://store.heartmath.com/innerbalance?utm_source=2163&utm_medium=affiliate&cpclid=f6b91c4679184c83b42560e381159591&utm_campaign=The+Dave+Asprey+Group Thank you to our sponsors! -Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. -BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 to save 20% off your first order of PerfectAmino. -ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. Resources: • HeartMath Instagram: https://www.instagram.com/heartmath/ • HeartMath Facebook: https://www.facebook.com/HeartMath • HeartMath TikTok: https://www.tiktok.com/@heartmathinc • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:25 — OG Biohacker 3:21 — What Is Heart Rate Variability? 7:10 — The Four Drummers: Understanding HRV Rhythms 11:50 — Real-Time Training vs Sleep Tracking 18:45 — The Science of Coherence and Consciousness 21:25 — Heart Synchronization in Groups 26:40 — Space Weather and Planetary Rhythms 31:40 — Solar Flares and Human Behavior 38:45 — The Emotional System Runs the Show 49:15 — Getting Started: Training Protocol 57:55 — Advanced Applications: Dating to Performance 1:01:46 — The Frequency Spectrum of Love 1:05:15 — The Heart’s Magnetic Field and Congruence See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 28

Discover how decoding your DNA can unlock the full potential of plant medicine. This episode delivers a cannabis masterclass for biohackers , revealing how personalized genetics are transforming human performance, brain optimization, and longevity. You’ll learn how to identify your ideal cannabis and supplement protocols, balance your endocannabinoid system, and turn precision data into powerful healing. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Len May, MSc , visionary authority in personalized medicine and CEO of EndoDNA , the world leader in DNA-based wellness technology. With over 25 years of pioneering work in genomics, epigenetics, and medicinal cannabis, Len’s patented DNA decoding system maps your unique genotypes to design tailor-made health solutions. His company holds the world’s largest real-world efficacy database in precision wellness, integrating functional medicine, AI-driven analytics, and genetic data to create personalized blueprints for optimal brain function and performance. Together, Dave and Len explore how your genetic code determines how you respond to cannabis, psychedelics, nootropics, and supplements—and how to use that data to reduce anxiety, improve sleep optimization, and enhance focus. You’ll learn how decoding your DNA can guide anti-aging strategies, mitochondrial performance, metabolism, and neuroplasticity, revealing new ways to live longer and smarter. This episode dives deep into the intersection of cannabis science, genomics, and biohacking. You’ll discover how genetic polymorphisms influence mood, cognition, and stress response, and how personalized medicine can help you make smarter decisions around ketosis, fasting, and recovery. From optimizing the endocannabinoid system to hacking your biology for resilience and longevity, this is the future of functional medicine in action. You’ll Learn: • How the endocannabinoid system regulates mood, focus, pain, and stress response • Which genetic polymorphisms affect cannabis sensitivity, anxiety risk, and dosing windows • How to use DNA testing to select cannabinoid and terpene ratios that fit your biology • Why delivery method matters and when sublingual dosing outperforms inhalation • How personalized cannabis protocols can support sleep optimization, recovery, and emotional regulation • The role of cannabinoids in mitochondrial function, neuroplasticity, and cognitive performance • How pharmacogenomics reduces antidepressant side effects and improves treatment matching • How to screen genetics for safer psychedelic use and avoid adverse reactions • What HLA and related markers reveal about mold sensitivity and inflammation This is essential listening for anyone serious about biohacking, brain optimization, longevity, anti-aging, functional medicine, and living Smarter Not Harder—with precision tools designed to upgrade your mind and body at the genetic level. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee , and the father of biohacking . With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS) . Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: cannabis biohacking, cannabis masterclass, Dave Asprey cannabis, DNA decoding, genetic testing for cannabis, personalized medicine, endocannabinoid system, cannabis genomics, cannabis and DNA, cannabis and genetics, cannabis nootropics, plant medicine biohacking, cannabis brain optimization, cannabis and neuroplasticity, cannabis for focus, cannabis and mitochondria, cannabis metabolism, cannabis for sleep, cannabis anti-aging, precision wellness, functional medicine, cannabis longevity, EndoDNA, Len May, cannabis and AI, biohacking genetics, cannabis and fasting, cannabis and ketosis, personalized supplements, cannabis and mood, cannabis stress response, genetic biohacking, cannabis cognitive performance Thank you to our sponsors! -Screenfit | Get your at-home eye training program for 40% off using code DAVE at https://www.screenfit.com/dave . -Essentia | Go to https://myessentia.com/dave and use code DAVE for $100 off The Dave Asprey Upgrade. -Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. -iRestore | Use code DAVE at https://www.irestore.com/ to unlock an exclusive discount on the iRestore Elite. Resources: • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: • 0:00 – Trailer • 1:25 – Introduction • 7:02 – Cannabis & The Endocannabinoid System • 13:30 – How It Works • 21:38 – Brain Health & Clinical Studies • 26:52 – Psychedelics & Genetic Testing • 31:37 – Genetics vs Epigenetics • 34:53 – Antidepressant Safety • 40:41 – Cannabis Success Stories • 46:02 – ADHD & Personality Genes • 50:54 – Mold, Nicotine & Mitochondria • 55:27 – GLP-1 & Metabolism • 1:00:34 – Microbiome & Medical Freedom See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 26

Dopamine isn’t the enemy—low brain energy is. When your mitochondria can’t make enough ATP, your neurons misfire, leading to fatigue, brain fog, and lack of focus. In this video, I explain why dopamine problems are really energy problems, how mitochondrial health drives motivation and clarity, and why creatine is one of the most effective and affordable nootropics for restoring mental performance. Learn the biohacks that protect your brain’s power plants and keep you sharp all day long. Chapters 0:00 – Introduction 0:22 – Brain energy vs dopamine 0:49 – ATP shortage causes fatigue 1:53 – Prefrontal cortex and energy 3:08 – Why ATP fuels focus and mood 4:40 – Stress, sleep and mitochondria 6:00 – Biohacks for energy production 7:39 – Backup battery: phosphagen system 8:46 – Creatine for brain energy & focus 13:18 – Vegans, women and creatine needs 15:07 – Best practices for dosing creatine 17:53 – Daily creatine + electrolytes Thank you to our sponsors! -ECHO Water | Go to http://echowater.com/dave and use code DAVE10 for 10% off your ECHO Flask. Connect with Dave Asprey! Website: https://daveasprey.com TikTok: https://www.tiktok.com/@daveaspreyofficial Instagram: https://www.instagram.com/dave.asprey/ Facebook: https://www.facebook.com/Daveaspreyofficial/ X: https://x.com/daveasprey YouTube: https://www.youtube.com/c/daveaspreybpr The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/ Danger Coffee: https://dangercoffee.com/DAVE15 Dave Asprey’s BEYOND Conference: https://beyondconference.com/ Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15 Upgrade Collective: https://www.ourupgradecollective.com Upgrade Labs: https://upgradelabs.com 40 Years of Zen: https://40yearsofzen.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 24

Upgrade your biology in 10 minutes with this week’s rundown from Dave Asprey. This episode breaks down the five biggest stories in biohacking and health-tech — from genetic rejuvenation to your future digital twin — giving you the tools to live longer, perform better, and stay ahead of the curve. This episode covers: • Vitamin D as the Surprising “Anti-Aging Pill” A new five-year randomized study shows that daily 2,000 IU vitamin D supplementation slowed telomere shortening by 140 base pairs compared to placebo, translating to measurable gains in biological youth. Vitamin D isn’t just for bones anymore — it’s a foundational longevity molecule. Source: Science Daily — https://www.sciencedaily.com/releases/2025/10/251022023132.htm • The Supercentenarian Gene That Rejuvenates Old Hearts Researchers at the University of Bristol identified a gene variant, LAV-BPIFB4 , common among people living past 100, that reversed cardiac aging in animal studies — restoring blood flow, heart strength, and tissue repair with a single treatment. It’s a glimpse into how gene therapy could soon democratize superhuman longevity. Source: University of Bristol News — https://www.bristol.ac.uk/news/2025/october/progeria.html • FDA Closes the “GRAS” Loophole — Supplements Enter a New Era The FDA just ended decades of self-certification for new dietary ingredients, requiring full agency review for anything entering the market. It’s the biggest shakeup in supplement regulation in years — raising quality, accountability, and trust across the entire industry. Source: Mintz FDA Flux Newsletter — https://www.mintz.com/insights-center/viewpoints/2791/2025-10-16-fda-flux-october-2025-newsletter • Microbes That Trigger Autophagy — Your Gut as an Anti-Aging Switch Scientists at the University of Basel discovered that certain dietary bacteria containing double-stranded RNA can directly trigger autophagy, the body’s built-in cell-recycling system. Fermented foods like kimchi, kefir, and sauerkraut may now be proven longevity tools for activating repair from the inside out. Source: University of Basel — https://www.unibas.ch/en/News-Events/News/Uni-Research/Longevity-research—Dietary-stress-supports-healthy-aging.html Further reading: Neuroscience News — https://neurosciencenews.com/dietary-rna-cellular-aging-29757/ • Your Medical Avatar Is Coming — The Digital Twin of You Forbes reports on the rise of personalized “medical avatars” — AI-powered digital twins built from your wearables and biometrics that can predict health risks, recommend interventions, and evolve alongside your biology. Doctors like Daniel Kraft call it generative health — a revolution in predictive medicine where your data literally becomes your doctor. Source: Forbes Innovation — https://www.forbes.com/sites/johnwerner/2025/10/21/wearables-ai-and-your-personal-medical-avatar/ This is essential listening for fans of biohacking, human performance, functional medicine, and longevity science who want real, actionable tools from Dave Asprey — the father of biohacking and founder of Bulletproof Coffee. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your lifespan, and upgrade every system in your body and mind. New episodes drop every Tuesday, Thursday, Friday, and Sunday. Dave asks the questions no one else will — and gives you the science-backed tools to become stronger, smarter, and more resilient. Keywords: vitamin D longevity, telomeres, BPIFB4 gene, cardiac rejuvenation, supplement regulation, GRAS FDA, autophagy, microbiome, fermented foods, biohacking news, medical avatar, digital twin, predictive medicine, Daniel Kraft, quantum health, wearable AI, Dave Asprey, The Human Upgrade Thank you to our sponsors! TRU KAVA | Go to https://trukava.com/ and use code DAVE10 for 10% off. HeartMath | Go to https://www.heartmath.com/dave to save 15% off. Timestamps: 0:00 — Introduction 0:18 — Story 1: Vitamin D & Telomeres 1:02 — Story 2: Longevity Gene Therapy 1:49 — Story 3: FDA Supplement Reform 2:38 — Story 4: Gut Bacteria & Autophagy 3:46 — Story 5: Medical Avatars 4:53 — Weekly Protocol 5:42 — Outro See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 23

This is Part 2 of the Nicotine Masterclass. If you haven’t heard Part 1 , start there for a full breakdown of nicotine’s mechanisms, myths, and the science behind its misunderstood role in longevity, nootropics, and human performance. Nicotine is one of the most misunderstood nootropics in the world—and one of the most powerful tools for brain optimization and longevity when used correctly. In this episode, Host Dave Asprey breaks down how to harness nicotine for cognitive enhancement, metabolism, and human performance without falling into addiction. You’ll learn the real science behind dosage, timing, and cycling, plus how nicotine interacts with mitochondria, acetylcholine, and neuroplasticity to boost focus, motivation, and mental energy. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR This is Part 2 of the Nicotine Masterclass. If you haven’t heard Part 1 , start there for a full breakdown of nicotine’s mechanisms, myths, and the science behind its misunderstood role in longevity, nootropics, and human performance. Host Dave Asprey reveals practical biohacking templates for using nicotine safely and effectively—covering metabolism genetics, stack combinations, and how nicotine fits into a smarter not harder lifestyle. You’ll discover how low-dose nicotine can support attention, memory, and even protect against neurodegenerative diseases like Alzheimer’s and Parkinson’s. Dave also shares his own five-year nicotine protocol, how he avoided dependence, and why nicotine can be a game-changer for brain and mitochondrial performance when used intelligently. You’ll Learn: • How to use nicotine as a safe, powerful nootropic for brain optimization and focus • The genetics of nicotine metabolism and why dose timing matters • How to stack nicotine with caffeine, theanine, and rhodiola for maximum energy and motivation • Why nicotine enhances mitochondria and PGC-1α for better metabolism and longevity • The truth about nicotine tolerance, cycling, and how to avoid addiction • How nicotine affects sleep, neuroplasticity, and dopamine signaling • What science says about nicotine’s protective effects against Alzheimer’s and Parkinson’s • How to integrate nicotine into a complete biohacking protocol with fasting, ketosis, and supplements This episode is essential for anyone exploring biohacking, functional medicine, fasting, ketosis, sleep optimization, and cognitive resilience. You’ll learn how nicotine stacks with caffeine, theanine, rhodiola, and supplements for sharper thinking and sustained focus—plus the key mistakes to avoid so you don’t wreck your sleep or metabolism. Whether you’re a seasoned biohacker or just beginning your journey, this episode gives you the science, tools, and protocols to elevate your mind and body safely. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee , and the father of biohacking . With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS) . Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: nicotine biohacking, nicotine masterclass, Dave Asprey nicotine, nicotine nootropics, nicotine cognitive enhancement, nicotine mitochondria, nicotine and dopamine, nicotine addiction prevention, nicotine cycling, nicotine dosage, nicotine metabolism, nicotine tolerance, nicotine and longevity, nicotine patch benefits, nicotine for focus, nicotine and acetylcholine, nicotine and caffeine stack, nicotine sleep effects, nicotine and Parkinson’s, nicotine brain optimization ** Listen to part 1 here: https://www.youtube.com/watch?v=WjehLsHaRnE&t=1063s ** Thank you to our sponsors! -GOT MOLD? | Go to http://gotmold.com/shop and use DAVE10 to save 10% and see what’s in your air. -Vibrant Blue Oils | Grab a full-size bottle for over 50% off at https://vibrantblueoils.com/dave . -ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. -MASA Chips | Go to https://www.masachips.com/DAVEASPREY and use code DAVEASPREY for 25% off your first order. Resources: • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 00:00 – Trailer 01:25 – Review of Pt 1 02:48 – Genetics & Metabolism 06:05 – Stacking with Other Compounds 09:23 – Tolerance & Dependence 13:42 – Fertility & Contraindications 17:05 – Real World Use Templates 21:40 – Travel & Jet Lag Protocol 24:29 – Biohacking Lifestyle Integration 25:31 – Longevity & Neuroprotection 28:24 – Medical Applications & Research 31:51 – Final Thoughts & Summary See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 21

Modern joint pain isn’t just wear and tear—it’s a systemic, metabolic disease that starts years before symptoms show. In this episode, you’ll learn how inflammation, mitochondria dysfunction, and immune imbalance trigger cartilage loss… and how to reverse it using targeted cytokine modulation, cellular regeneration, and smarter supplements for longevity and human performance. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Kiran Krishnan, an expert microbiologist and advisor to Calroy Health Sciences. He’s the founder of Microbiome Labs—one of the most trusted microbiome-focused brands in functional medicine—and a formulator behind cutting-edge supplements like Arterosil and Vascanox. With over two decades of experience, Kiran has launched multiple health ventures, authored scientific textbook chapters, published clinical trials, and holds global patents in human health. He’s a leading authority on systemic inflammation, mitochondrial dysfunction, and gut-driven disease—and one of the few voices making complex biology accessible for real-world results. He breaks down their new supplement Cartigenix HP, and how cytokines like IL-6 and TNF-alpha flip your cartilage cells from anabolic repair to catabolic destruction, how mitochondrial decline speeds up joint damage, and why most modern painkillers make your joints worse. You’ll learn how a specialized blend of boswellia and celery seed reprograms inflammation, why walking beats medication in clinical trials, and how fasting, nitric oxide, and gut health work together to optimize joint regeneration. You’ll learn: • How cartilage cells (chondrocytes) rely on mitochondria for tissue repair • Why global cytokines like IL-6 and TNF-alpha drive joint degradation and brain fog • How cartilage begins to break down in your teens—and what to do about it now • The surprising clinical data on walking distance, inflammation markers, and recovery • Why most supplements and NSAIDs fail—and what actually rebuilds joints • How diet and leaky gut create 5-day inflammation spikes from a single fast-food meal • The mitochondrial link between joint pain, cardiovascular risk, and depression • Why perimenopausal women are at 10x higher risk for arthritis—and how to prevent it • How to track your biological joint age using imaging and systemic inflammation labs This is essential listening for anyone serious about biohacking, functional medicine, pain-free aging, and human performance. Whether you’re lifting heavy, walking daily, or just trying to stay mobile into old age, this episode gives you the science and tools to reverse joint degeneration and extend your healthspan. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee , and the father of biohacking . With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS) . Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Joint cartilage regeneration, IL-6 inflammation suppression, TNF-alpha cytokine modulation, Chondrocyte mitochondrial repair, Catabolic to anabolic tissue shift, Osteoarthritis reversal, Rheumatoid arthritis inflammation, Mitochondria and collagen synthesis, Boswellia seratol extract, Celery seed COX inhibition, Matrix metalloproteinase (MMP) inhibition, Synovial fluid inflammation, Leaky gut and joint pain, Six-minute walk test improvement, Global cytokine markers, High sensitivity CRP reduction, ESR sedimentation rate, Uric acid crystal formation, Post-prandial glucose walking, Cartilage MRI biomarkers, Functional medicine joint support, Fasted repair stacking, Vasodilation and nitric oxide, Anti-inflammatory supplement stacking, NF-kB pathway reduction, Joint space biological age, Microvascular circulation and cartilage, Caloric load and cytokine spike, Perimenopause and arthritis risk, Joint tissue anabolic activation **Get an exclusive discount for podcast listeners at calroy.com/dave : https://calroy.com/product/cartigenix-hp/?lp=dave ** Thank you to our sponsors! -BodyGuardz | Visit https://www.bodyguardz.com/ and use code DAVE for 25% off. -BiOptimizers | Go to http://bioptimizers.com/dave and use code DAVE15 to get 15% off your order. -Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. -Caldera + Lab | Go to https://calderalab.com/DAVE and use code DAVE at checkout for 20% off your first order. Resources: • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:25 — Introduction 2:01 — Why Modern Medicine Fails at Joint Pain 3:07 — Painkillers That Accelerate Joint Damage 7:35 — Rheumatoid vs. Osteoarthritis Explained 8:54 — Cytokines That Destroy Cartilage 12:10 — Arthritis Begins in Your Teens 15:35 — 75% Pain Reduction in 7 Days 18:35 — The Science Behind Boswellia & Celery Seed 24:10 — Six-Minute Walk Test Results 25:45 — The $200/Month Painkiller Trap 28:53 — Proof Cartilage Can Regrow 31:01 — Mitochondria and Joint Repair 32:29 — Inflammation Links to Heart Disease 35:52 — Why Glucosamine Doesn’t Work 37:07 — Silent Arthritis in 90% of Adults 40:44 — Why Women Face Higher Joint Risk After 40 45:52 — Food as the #1 Inflammation Trigger 47:23 — Fasting & Cartogenics Stack for Repair 50:27 — Movement Snacks and Efficient Training 55:54 — Why Joints Heal Slower Than Muscles 57:48 — Dave’s Stack and Final Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 19

Biohacking isn’t just food + exercise, it’s about fixing the invisible disruptors wrecking your biology. EMFs, mold, toxins, mitochondrial stress, these are the real reasons you still feel tired, foggy, or inflamed even on a perfect diet. I’ve been there. I lost 100 lbs, built Bulletproof Coffee, and discovered why food alone isn’t enough. In this video, I’ll show you what’s actually holding back your energy, focus, and longevity… and how to finally feel truly bulletproof. Chapters: 0:00 – Introduction 1:30 – The hidden disruptors wrecking your health 2:15 – EMFs: invisible energy thieves 3:00 – Mold exposure: the silent killer in your home 4:00 – How toxins block your nutrients 5:10 – Mitochondria: the real source of energy 6:20 – Detox hacks that actually work 7:30 – Binders: the secret to flushing toxins 8:30 – Rebuilding nutrients for lasting energy 9:20 – The missing biological switch: nervous system safety 10:30 – Resetting your circadian rhythm naturally 11:30 – Box breathing: a biohack for instant calm 12:20 – Gratitude, digestion & unlocking thrival mode Connect with Dave Asprey! Website: https://daveasprey.com TikTok: https://www.tiktok.com/@daveaspreyofficial Instagram: https://www.instagram.com/dave.asprey/ Facebook: https://www.facebook.com/Daveaspreyofficial/ X: https://x.com/daveasprey YouTube: https://www.youtube.com/c/daveaspreybpr The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/ Danger Coffee: https://dangercoffee.com/DAVE15 Dave Asprey’s BEYOND Conference: https://beyondconference.com/ Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15 Upgrade Collective: https://www.ourupgradecollective.com Upgrade Labs: https://upgradelabs.com 40 Years of Zen: https://40yearsofzen.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 17

Upgrade your biology in 10 minutes with this week’s rundown from Dave Asprey. T This episode covers: • Longevity Scores Are Going Mainstream Elegant Hoopoe’s new clinics are using 56 biomarkers to track biological aging — and early users are reporting up to six years reversed in under two months. Could scoring systems replace reactive healthcare? Source: Morningstar via PR Newswire — https://www.morningstar.com/news/pr-newswire/20251014ln95054 • AI Heart Scans Spot Trouble Sooner Hospitals are using machine learning to analyze echocardiograms in real time — making heart diagnostics faster, cheaper, and more accurate, even without top specialists on site. Source: Crescendo.AI News — https://www.crescendo.ai/news/latest-ai-news-and-updates • Brain Training That Rebuilds Neurotransmitters McGill’s INHANCE trial shows that 10 weeks of digital training on BrainHQ doesn’t just improve memory — it chemically rejuvenates acetylcholine pathways. That’s measurable neuroplasticity. Source: Longevity.Technology — https://longevity.technology/news/brain-training-restores-youth-to-aging-minds/ • HLTH 2025 Unveils Digital Twins & Real-Time Immune Wearables This year’s HLTH conference put bio-individuality front and center: AI twins that simulate your biology, hormone-tracking wearables, and apps syncing with EMRs to turn raw data into real decisions. Source: HLTH Official — https://hlth.com/2025event • One Blood Test, Many Diagnoses New multi-panel tests rolling out in clinics screen for dozens of diseases from a single draw — boosting compliance, streamlining early detection, and making full-spectrum testing routine. Source: Instagram Science Updates — https://www.instagram.com/p/DP0oGGTiiT5/ This is essential listening for fans of biohacking, hacking human performance, functional medicine, and longevity who want actionable tools from Host Dave Asprey and a guest who embodies what it means to age with energy, clarity, and vitality. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: longevity score, elegant hoopoe, AI heart scans, brainHQ, acetylcholine, McGill INHANCE trial, HLTH 2025, digital twins, hormone wearables, immune tracking, biological age, multi-panel blood test, early detection, personalized medicine, Dave Asprey, Human Upgrade, biohacking news, health tech, performance medicine, smart diagnostics Thank you to our sponsors! -SKILLSwitch | If you’re ready for the best sleep of your life, order now at https://www.switchsupplements.com/ and use code DAVE for 20% off. -EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE for 40% off. Resources: • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Introduction 0:18 — Story 1: Elegant Hoopoe Longevity Score 1:26 — Story 2: AI-Assisted Echocardiograms 2:17 — Story 3: Brain HQ Cognitive Training Study 3:03 — Story 4: Digital Twins at HLTH Conference 4:13 — Story 5: Single Vial Blood Testing 5:04 — Five Day Experiment 5:46 — Closing See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 16

Most people try to “heal” their brain with supplements, mindset, or meditation—but this episode reveals the deeper protocol to actually grow a new brain, reverse stress damage, activate 1,100 healing genes, and unlock higher human performance at any age. You’ll learn how neuroplasticity, mitochondria repair, plant-based NRF2 activators, and energetic practices work together to rebuild the brain and extend longevity. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Alberto Villoldo, Ph.D.—medical anthropologist, neuroscientist, energy medicine pioneer, and founder of The Four Winds Society, the gold-standard school for modern shamans. He has spent 25+ years studying Amazonian and Andean healing traditions, led the Biological Self-Regulation Lab at San Francisco State University to explore psychosomatic medicine, and authored more than 25 bestselling books on neuroscience, functional medicine, and energy healing. Few people on earth bridge ancient biohacking and modern brain science at this level. He also reveals the forms of nicotine that are safest (spoiler: it’s not vapes or cigarettes), how nicotine works at the receptor level, and what the science says about long-term health effects. This episode blends functional medicine, brain optimization, and biohacking into one powerful, myth-busting breakdown. You'll learn : • How to grow a new brain every 22 days using neuroplasticity and mitochondria support • Why plant medicines and NRF2 activators can turn on 1,100 healing genes in 24 hours • The surprising link between nootropics, psychedelics, serotonin, and endogenous DMT • How mindset, belief systems, and placebo/nocebo shape immune function and metabolism • Why RFK’s chronic disease warning connects to viral evolution and immune collapse • The real reason carnivore diets work—and when they fail without gut repair • Peptides, GLP-1 agonists, and the future of functional medicine hacking • Why most people sabotage themselves and how to stop fighting your own biology This is essential listening for anyone serious about biohacking, human performance, and longevity , and for those who want to understand how functional biology and mitochondrial science are redefining recovery, energy, and aging. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee , and the father of biohacking . With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS) . Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: NRF2 activation, Neurogenesis and hippocampus repair, Plant-based epigenetic triggers, Psychosomatic health, Serotonin to DMT conversion, Pineal gland methylation, Parasites and brain inflammation, Viral-driven evolution, GLP-1 agonists and longevity, Psilocybin lifespan extension, Autophagy and brain cleanup, Energetic medicine training, Functional peptides, BPC-157, Breathwork and CO2 tolerance, mTOR cycling, Cold exposure and dopamine, Mindset-driven immune function Thank you to our sponsors! • EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE for 40% off. • Essentia | Go to https://myessentia.com/dave and use code DAVE for $100 off The Dave Asprey Upgrade. • Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. • fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Resources: • Learn more from Alberto at: www.thefourwinds.com and www.albertovilloldo.net • Buy the book ‘Grow A New Brain’: https://a.co/d/5lVhrVy • Business of Biohacking | Register to attend October 20-23 in Austin, TX https://businessofbiohacking.com/ • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:25 — Introduction & Ayahuasca Story 3:15 — Shamanism Beyond Plant Medicine 6:53 — Losing Your Mind to Evolve 10:45 — The 22-Day New Brain Cycle 12:53 — Plant Communication & Direct Knowing 15:35 — Parasites, Liver Failure & Brain Damage 20:25 — Remote Healing & CIA Research 22:40 — Tryptophan, Turkey Farmers & Brain Chemistry 25:19 — Viruses as Evolutionary Drivers 30:30 — Psilocybin & Life Extension 35:25 — Healing with Mindset + Biology 38:52 — Spirit, Purpose & Growing Gods 43:49 — Plants, Protein & mTOR 49:07 — Training the Four Brains 51:16 — Cold Exposure: Pain vs Suffering 54:40 — Who Am I? Living the Question 55:25 — Closing See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 14

Nicotine isn’t just addictive—it might be one of the most misunderstood nootropics in modern medicine. In this masterclass, you’ll learn how controlled, low-dose nicotine may enhance brain performance, boost neuroplasticity, improve mitochondrial function, and potentially extend lifespan. Host Dave Asprey breaks down the surprising science behind this controversial compound, separating fact from fear—and exposing the real risks that nobody talks about. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR You’ll discover how nicotine affects neurotransmitters, why it may help with ADHD and focus, and how it compares to other cognitive enhancers like caffeine, nootropics, and even smart drugs. Dave explores how nicotine can be used to hack metabolism, enhance sleep optimization, and support fasting or ketosis protocols—if used properly. He also reveals the forms of nicotine that are safest (spoiler: it’s not vapes or cigarettes), how nicotine works at the receptor level, and what the science says about long-term health effects. This episode blends functional medicine, brain optimization, and biohacking into one powerful, myth-busting breakdown. You’ll Learn: • How nicotine affects mitochondria, neurotransmitters, and dopamine signaling • Why nicotine may boost neuroplasticity, memory, and attention span • How low-dose nicotine compares to caffeine, modafinil, and other nootropics • The safest delivery forms (and the ones to avoid) • Whether nicotine supports or hinders longevity and cognitive resilience • How it can be stacked with supplements, fasting, or ketosis • What functional medicine says about chronic use, addiction, and withdrawal This is essential listening for anyone serious about biohacking, human performance, and longevity , and for those who want to understand how functional biology and mitochondrial science are redefining recovery, energy, and aging. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee , and the father of biohacking . With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS) . Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Nicotine microdosing, Nicotinic acetylcholine receptors, Dopamine and motivation, Cognitive enhancement, Alzheimer’s prevention, Neuroinflammation, Mitochondrial function, TNF-alpha reduction, Vagus nerve activation, Longevity biohacking, Nicotine vs smoking, Nootropics, Attention and vigilance, Ketosis and metabolism, Functional medicine, Nicotine patches and gum, Addiction and tolerance, Receptor desensitization, Withdrawal protocols, Deep work performance Thank you to our sponsors! -TRU KAVA | Go to https://trukava.com/ and use code DAVE10 for 10% off. -HeartMath | Go to https://www.heartmath.com/dave to save 15% off. -Leela Quantum Tech | Check out all HEAL360 products and research and get 10% off at https://leelaq.com/DAVE . -Calroy | Head to https://calroy.com/dave for an exclusive discount. Resources: • Business of Biohacking | Register to attend October 20-23 in Austin, TX https://businessofbiohacking.com/ • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Introduction 1:27 — History & Background of Nicotine 4:34 — How Nicotine Works 15:12 — Benefits & Research 16:43 — Risks & Who Should Avoid It 21:39 — Delivery Methods & Dosing 26:30 — Conclusion & Next Steps See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 13

These "toxic foods" are one of the biggest hidden threats to your health and most people are eating them every single day without realizing it. These cheap industrial foods are marketed as “healthy,” but the truth is they damage your cells, drive inflammation, and speed up aging. In this video, I’m exposing the dark history behind how they ended up in our food system, why regulators don’t protect you, and the toxic process used to make them. I’ll also show you what to cook with instead so you can lower inflammation, protect your brain, and get back the vitality the food industry has been stealing from you. If you care about longevity, energy, and real health, not marketing lies, this is one video you don’t want to miss. Chapters: 0:00 – Introduction 0:50 – What They Don’t Tell You About This 2:40 – How Healthy Fats Become Toxic Poisons 3:40 – The Food Industry’s Biggest Switch 5:37 – #1: The Everyday Additive That Wrecks Your Brain 6:51 – #2: The Snack Food Staple That Fuels Inflammation 7:55 – #3: The “Healthy” Oil Used in Engines 8:57 – #4: The Candle Wax That Became Food 9:40 – #5: The Cooking Oil That Ages You Faster 10:23 – #6: The Gasoline Replacement You’re Eating 11:01 – #7: The Wine Waste Product in Your Pantry 12:19 – Bonus: The One Contaminated with Heavy Metals 13:59 – How To Protect Yourself & Choose Real Fats 15:36 – Final Warning: The Food System Is Rigged _______ Connect with Dave Asprey! Website: https://daveasprey.com TikTok: https://www.tiktok.com/@daveaspreyofficial Instagram: https://www.instagram.com/dave.asprey/ Facebook: https://www.facebook.com/Daveaspreyofficial/ X: https://x.com/daveasprey YouTube: https://www.youtube.com/c/daveaspreybpr The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/ Danger Coffee: https://dangercoffee.com/DAVE15 Dave Asprey’s BEYOND Conference: https://beyondconference.com/ Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15 Upgrade Collective: https://www.ourupgradecollective.com Upgrade Labs: https://upgradelabs.com 40 Years of Zen: https://40yearsofzen.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 10

What if you could improve your mitochondria, oxygen efficiency, and recovery in just 20 minutes a day—by breathing energized water? This episode explores one of the most surprising breakthroughs in biohacking and how it can help you live longer, think clearer, and perform better. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey talks with Rowena Gates , co-founder of NanoVi , a therapeutic device backed by biophysics research that supports protein repair and mitochondrial communication. Her work reveals how structured water inside your cells drives neuroplasticity, cellular regeneration, and stress resilience—offering a new pathway to recovery, energy, and longevity. You’ll learn how structured water affects mitochondrial efficiency, how it compares to recovery methods like cold therapy and fasting, and why improved VO₂ max may correlate with a longer lifespan. Dave and Rowena also explore how NanoVi stacks with supplements, nootropics, ketosis, and functional medicine to enhance brain optimization, metabolism, and human performance. You’ll Learn: • How structured water boosts mitochondrial function and VO₂ max • The difference between hydration and energized cellular water • What happens to your brain and heart rate variability in 20 minutes of NanoVi use • The link between water structure, protein repair, and recovery • How biohackers combine NanoVi with fasting, cold therapy, and sleep optimization for faster results • Why stronger mitochondrial communication can extend lifespan and upgrade cognitive function They explore how structured water, mitochondrial repair, and recovery science intersect to create a smarter approach to health and longevity. You’ll also learn how optimizing cellular communication, oxygen efficiency, and stress resilience can accelerate healing, improve focus, and extend lifespan. This is essential listening for anyone serious about biohacking, human performance, and longevity , and for those who want to understand how functional biology and mitochondrial science are redefining recovery, energy, and aging. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee , and the father of biohacking . With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS) . Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: NanoVi, Structured water, Energized water, Biohacking, Dave Asprey, Mitochondrial repair, Mitochondrial communication, Human performance, Longevity, Recovery science, Oxidative stress, Protein repair, Redox signaling, Cellular hydration, Functional medicine, VO₂ max, Neuroplasticity, Brain optimization, Cellular energy, Stress resilience, Cold therapy, Fasting, Sleep optimization, Breathwork, Nootropics, Metabolism, Oxygen efficiency, ATP production, Cellular regeneration, Anti-aging, Smarter Not Harder **To level up your mitochondria with a NanoVi: visit https://eng3corp.com/dave/ ** Resources: • Business of Biohacking Summit | Register to attend October 20-23 in Austin, TX https://businessofbiohacking.com/ • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:25 — Introduction to NanoVi 4:01 — How to Use NanoVi 6:23 — Understanding Ordered Water 9:16 — Scientific Evidence & Studies 13:02 — Pricing & Accessibility 15:02 — Mitochondrial Function & MiScreen Results 19:55 — Brain Function & Cognitive Benefits 23:47 — How Ordered Water Works 27:34 — Cellular Communication & Fascia 30:14 — Heart Rate Variability & Stress Reduction 34:54 — Athletic Performance & Recovery 38:52 — Mental Health & Sleep Benefits 42:00 — Supplement Stacking 45:50 — Deep Sleep & Parasympathetic State 48:48 — Chronic Conditions & Fatigue 51:54 — Meditation & Brain Training 55:42 — Brain Injury & Resilience 59:36 — Conclusion & Where to Get It See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 9

AI is transforming medicine at a speed never seen before. In this episode, you’ll discover how digital twins and artificial intelligence will revolutionize drug discovery, eliminate human trials, and personalize your biology for longevity and high performance. Host Dave Asprey breaks down how AI can now simulate virtual cells and tissues, running clinical experiments in minutes instead of years to create truly individualized medicine. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Dr. Derya Unutmaz is a world-renowned immunologist, systems biologist, and professor at The Jackson Laboratory. With more than 150 scientific papers, he’s a leading expert in immune system research and one of the first scientists to pioneer the concept of digital twins for biology. His groundbreaking work uses AI to model how immunity, metabolism, and aging interact—creating new possibilities for personalized medicine, disease prevention, and lifespan extension. Host Dave Asprey and Dr. Unutmaz reveal how AGI will soon outperform doctors, accelerate functional medicine, and optimize human biology far beyond today’s standards. You’ll learn how the immune system drives inflammation and aging, how to re-engineer it for resilience, and why compounds like GLP-1 and metformin may add years to your life. You’ll Learn: • How digital twins will end human drug testing • Why AGI could replace doctors and computer jobs within five years • How AI models immune function, metabolism, and aging • The role of mitochondria and inflammation in longevity • How GLP-1 drugs and metformin extend lifespan • What continuous biological monitoring means for health tracking • How AI is transforming functional medicine and personalized care • Why NAD and energy metabolism are key to human performance They explore how artificial intelligence, biohacking, and systems biology intersect to create a smarter approach to health and longevity. You’ll also learn how understanding immune balance, metabolism, and mitochondrial function helps build resilience and extend your lifespan. This is essential listening for anyone serious about biohacking, hacking human performance, and extending longevity through personalized medicine, functional biology, and cutting-edge AI innovation. This is essential listening for anyone serious about biohacking, hacking human performance, improving mobility, and extending longevity. You’ll also learn how neuroplasticity, metabolism, and brain optimization all connect to the way you move. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: AI medicine, Digital twins, Functional medicine, Biohacking, Longevity, Immune system, Inflammation, Personalized medicine, GLP-1 therapy, Metformin, NAD boosters, Mitochondrial function, Metabolism, AGI, Clinical trials, Human performance, Aging research, Systems biology, Immunology, Smarter Not Harder Thank you to our sponsors! BrainTap | Go to http://braintap.com/dave to get $100 off the BrainTap Power Bundle. MASA Chips | Go to https://www.masachips.com/DAVEASPREY and use code DAVEASPREY for 25% off your first order. Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order Resources: • Keep up with Derya’s work: https://x.com/derya_?lang=en • Business of Biohacking Summit | Register to attend October 20-23 in Austin, TX https://businessofbiohacking.com/ • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 00:00 — Trailer 01:25 — Intro 02:26 — AI’s Role in Extending Lifespan 02:56 — Regulatory Frameworks and Medical Adoption 05:19 — Problems with the Immune System 08:19 — Chronic Fatigue and Long COVID Research 10:32 — Modern Testing and Multi-Omic Analysis 14:07 — Personal Longevity Strategy and Supplements 15:17 — Understanding Exhausted Cells 23:43 — Personalization in Medicine and AI Analysis 31:35 — Longevity Escape Velocity 36:13 — AI Doctors and Prescriptions 39:55 — Data Quality Concerns in AI Training 43:19 — The Future of Wearable Technology 45:50 — Revolutionizing Education with AI 49:04 — The Future of Higher Education 52:03 — Future of Work and AI Agents See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 7

Most people think about heart disease and metabolism when they talk about longevity, but too few talk about joint health. In this episode, you’ll discover how to biohack your joints to prevent pain, reverse damage, and move like you’re decades younger. Host Dave Asprey reveals how functional movement, core stability, and recovery can transform joint health, helping you maintain pain-free performance for life. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Dr. Jason Snibbe is a globally recognized, board-certified orthopedic surgeon and a pioneer in advanced, minimally invasive, and robotic surgeries of the shoulder, elbow, hip, and knee. Fellowship-trained in Sports Medicine and Robotic Joint Reconstruction, he has achieved the lowest complication rate at Cedars-Sinai Medical Center and is the official orthopedic surgeon for the Los Angeles Clippers. He also serves as an orthopedic consultant for the Los Angeles Lakers, Los Angeles Sparks, Los Angeles Angels of Anaheim, and Los Angeles Kings. As a founding and managing partner in DOCS Spine and Orthopedics and Docs Surgical Hospital, Dr. Snibbe lectures and trains surgeons around the world in his specialized techniques. Host Dave Asprey and Dr. Snibbe uncover how weak glutes, poor core engagement, and bad footwear accelerate joint aging, and how functional movement training and fascia care can protect your body from surgery. You’ll learn why proper biomechanics are central to human performance and longevity, how hypermobility and fascia impact neuroplasticity, and the latest biohacking tools for recovery and joint regeneration. You’ll Learn: • The real cause of joint damage and how to prevent it • How to build a stronger core and glutes for long-term joint stability • Why footwear choices can make or break your movement quality • The truth about fascia, stretching, and strength training • When to use PRP, stem cells, and biologics for healing • How hypermobility affects your joints, brain, and longevity • Daily mobility and recovery habits that prevent future surgery They explore how biologics like PRP, stem cells, and exosomes are changing orthopedic recovery and joint repair, and why functional medicine is moving beyond surgery toward regeneration. You’ll hear how precision movement, fascia work, and strength training protect your joints and enhance human performance and longevity. This is essential listening for anyone serious about biohacking, hacking human performance, improving mobility, and extending longevity. You’ll also learn how neuroplasticity, metabolism, and brain optimization all connect to the way you move. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Joint biohacking, Orthopedic regeneration, Functional movement patterns, Core stability training, Glute activation exercises, Fascia mobility, Hypermobility syndrome, Ehlers-Danlos collagen disorder, Foot biomechanics, Pronation and supination, Arch support orthotics, Barefoot gait training, Stem cell joint repair, PRP knee therapy, Exosome orthopedic recovery, Meniscus tear alternatives, Robotic joint surgery, Posture correction, Gait analysis technology, Pain-free longevity Thank you to our sponsors! TRU KAVA | Go to https://trukava.com/ and use code DAVE10 for 10% off. BON CHARGE | Go to https://boncharge.com and use code DAVE for 15% off. OneSkin | For a limited time, try OneSkin for 15% off with code DAVE at https://www.oneskin.co/DAVE Business of Biohacking Summit | Register to attend October 20-23 in Austin, TX https://businessofbiohacking.com/ Resources: • Learn more about Dr. Snibbe’s work: https://www.drjasonsnibbe.com/ • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: • 0:00 — Trailer • 1:28 — Introduction • 2:38 — The Kinetic Chain • 9:34 — Core and Glutes • 12:18 — Stretching and Fascia • 17:32 — Sleep and Recovery • 18:49 — Vibration Therapy • 23:47 — Gait and Compensation • 30:47 — Robotic Surgery • 34:28 — Future of Medicine • 39:23 — Footwear Mistakes • 48:48 — Wearables and Tech • 55:13 — Stem Cells and Biologics • 1:01:20 — Final Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 5

Remote work might feel like freedom, but your biology disagrees. In this video, I break down how your work-from-home setup is hijacking your hormones: crushing testosterone, spiking cortisol, and wrecking insulin sensitivity. I’ll show you exactly how posture, light, movement, and meal timing secretly control fat gain, energy crashes, and libido drops... and how to take back control without quitting your job or starving yourself. This is about biohacking your environment to work for you—not against you. Chapters: 0:00 – Introduction 1:04 – How Working From Home Disrupts Your Biology 1:58 – The Silent Hormonal Downshift of Remote Workers 3:29 – How Posture Sends Stress Signals to Your Brain 4:49 – Fix This: 3 Postural Resets to Normalize Hormones 5:50 – The Hormone Remote Work Destroys Most: Insulin 6:59 – How To Restore Insulin Sensitivity 9:45 – Why Light Is More Powerful Than Food Connect with Dave Asprey! Website: https://daveasprey.com TikTok: https://www.tiktok.com/@daveaspreyofficial Instagram: https://www.instagram.com/dave.asprey/ Facebook: https://www.facebook.com/Daveaspreyofficial/ X: https://x.com/daveasprey YouTube: https://www.youtube.com/c/daveaspreybpr The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/ Danger Coffee: https://dangercoffee.com/DAVE15 Dave Asprey’s BEYOND Conference: https://beyondconference.com/ Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ Upgrade Collective: https://www.ourupgradecollective.com Upgrade Labs: https://upgradelabs.com 40 Years of Zen: https://40yearsofzen.com TrueDark Glasses: https://truedark.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 3

Upgrade your week in just 10 minutes with D(AI)ve Asprey’s essential rundown on what matters most in longevity, biohacking, AI health tech, and medical freedom. This episode covers: • Apple Cider Vinegar Myth Busted A weight-loss study just got retracted. ACV will not melt fat, but it may blunt glucose spikes or ease digestion when diluted in water before carb-heavy meals. Skip the shots and protect your teeth. Source: https://www.sciencedaily.com/releases/2025/10/251001092216.htm • NMN Is Back The FDA reversal puts NMN back on shelves as a clean NAD precursor. Dave explains why quality, cycling, and stacking with anti-inflammatory strategies make the difference. Source: https://www.prnewswire.com/news-releases/renue-by-science-celebrates-fda-reversal-confirming-nmn-is-lawful-for-use-in-dietary-supplements-302573317.html • Poor Sleep Ages Your Brain Machine learning MRI studies show poor sleep makes your brain biologically older and raises dementia risk. Dave shares the three dials to track (deep sleep, REM, resting heart rate) and the three biggest levers to fix them. Source: https://www.sciencedaily.com/releases/2024/10/241023171543.htm • Psilocybin for Lasting Reset New research finds a single guided dose can unlock plasticity, ease pain patterns, and lift mood for weeks. Dave outlines safe protocols, integration steps, and why it is a strategic reset tool, not a party trick. Source: https://www.sciencedaily.com/releases/2025/06/250616040215.htm • AI Detects Cancer Earlier A new AI tool called DOLPHIN can find hidden genetic markers to flag cancer risk sooner. Pairing high tech scans with low tech terrain fixes like sleep, muscle, and insulin control is the prevention model that works. Source: https://www.sciencedaily.com/releases/2025/10/251001092206.htm All source links provided for easy reference to the original reporting and research above. This is essential listening for fans of biohacking, hacking human performance, functional medicine, and longevity who want actionable tools from Host Dave Asprey and a guest who embodies what it means to age with energy, clarity, and vitality. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday (audio-only), and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Apple cider vinegar, weight loss myths, NMN supplements, NAD precursors, cellular energy, sleep and dementia, brain aging, deep sleep optimization, REM sleep, psilocybin therapy, BDNF, neuroplasticity, pain relief, mood reset, AI cancer detection, early cancer screening, biohacking news, longevity science, Dave Asprey, Human Upgrade podcast Thank you to our sponsors! Screenfit | Get your at-home eye training program for 40% off using code DAVE https://www.screenfit.com/dave . LYMA | Go to https://lyma.sjv.io/gOQ545 and use code DAVE10 for 10% off the LYMA Laser. Vibrant Blue Oils | Grab a full-size bottle for over 50% off at https://vibrantblueoils.com/dave . Resources: • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Introduction 0:18 — Story 1: Apple Cider Vinegar and Weight Loss 1:49 — Story 2: NMN is Back in Supplements 3:31 — Story 3: Sleep and Brain Health 5:39 — Story 4: Psilocybin and Lasting Relief 7:49 — Story 5: AI Tool DOLPHIN for Early Cancer Signals 9:48 — Conclusion & Weekly Roundup See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 2

Gravity may be the most ignored signal in human biology, and it could be the missing key to unlocking fat loss, brain optimization, and true longevity. In this episode, you’ll learn how Earth’s pull shapes your metabolism, mood, and resilience, and discover practical hacks to fight “gravity intolerance” so you can perform better, live longer, and upgrade every system in your body. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Dr. Brennan Spiegel, a Professor of Medicine and Public Health at UCLA, Director of Health Services Research at Cedars-Sinai, and author of Pull: How Gravity Shapes Your Body, Steadies the Mind, and Guides Our Health . A leading voice in digital health and immersive medicine, Dr. Spiegel brings decades of clinical and research experience exploring the intersection of the gut-brain axis, neuropsychology, and mind-body medicine. In this episode, he reveals why gravity influences everything from gut health to depression — and why modern medicine has largely ignored its role. His work bridges functional medicine, neuroscience, and biohacking to uncover a hidden force that shapes human performance at every level. You’ll Learn: • Why gravity is the most ignored biohacking signal in human health • How gravity intolerance shows up as back pain, fatigue, obesity, and depression • The surprising connection between gravity, serotonin, and mood regulation • How weighted vests, balance boards, and proprioception training hack graviception • Why sleep optimization, posture, and fascia resilience are gravity-based health tools • How Earth’s pull influences gut health, metabolism, and even consciousness You’ll learn how gravity connects to obesity, back pain, blood pressure, serotonin, and even consciousness. Dave and Dr. Spiegel explore how weighted vests, balance boards, vibration, and sleep optimization can hack your body’s response to gravity. This channel dives into mitochondria, neuroplasticity, fasting, ketosis, supplements, and how biohackers can apply these insights alongside tools like cold therapy, nootropics, and even Danger Coffee to build resilience and extend longevity. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday (audio-only), and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Gravity intolerance, Graviception, Serotonin and gravity, Tensegrity fascia system, Interstitium organ discovery, Piezoelectric cell membranes, Weighted vest training health, Balance board proprioception, Inclined bed sleep therapy, Gravity and depression, Obesity as a gravity disease, Low blood pressure gravity link, Crohn’s disease altitude flares, Gravity and microbiome diversity, Glymphatic drainage sleep optimization, Space travel gravity health risks, Astronaut vision loss microgravity, Vagus nerve and gravity, Collagen and gravity resilience, Barefoot running gravity mechanics Thank you to our sponsors! Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Timeline | Head to https://www.timeline.com/dave to get 20% off. Resources: • Pre-order Brennan’s Book: https://a.co/d/ik2C9iB • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:30 — Intro 4:14 — Gravity and Human Evolution 5:39 — Why Medicine Ignores Gravity 8:43 — Signs of Gravity Intolerance 12:18 — Training Gravity Resilience 16:46 — Gravity in Space 20:34 — Managing Gravity When Flying 23:59 — NASA’s Gravity-Diet Link 26:55 — Serotonin and Gravity 37:42 — Gravity and Sleep 50:24 — Obesity as a Gravity Issue 55:39 — Movement and Balance 57:38 — Gravity-Resistant Exercises See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 30

Most people chase fat loss, focus, and energy with caffeine or stimulants, but the real key to brain optimization and human performance is a pharmaceutical nootropic that activates your wakefulness circuits without jitters or a crash. In this episode, you’ll learn how Modafinil upgrades mitochondria, sharpens neuroplasticity, improves metabolism, and extends longevity with evidence-based tools used by elite thinkers, fighter pilots, and world leaders. This is not a sales pitch. It is an educational masterclass on how to upgrade your brain beyond what it can ever do naturally. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey takes you inside the full playbook of Modafinil, a prescription nootropic often called the “real Limitless pill.” With over 20 years of personal experience using it daily alongside biohacking stacks of supplements, fasting, ketosis, cold therapy, sleep optimization, and Danger Coffee, Dave explains why Modafinil is more than just a wakefulness drug. It is a brain optimization tool that supports mitochondrial energy, resilience, and cognitive clarity. Together with decades of research, Dave shows you how Modafinil compares to stimulants like Adderall and caffeine, why it was adopted by Air Force pilots and Wall Street executives, and how functional medicine strategies can help you safely integrate it into a broader biohacking and longevity stack. This is a masterclass in hacking cognition and performance, designed for anyone who wants a sharper brain, stronger metabolism, and a more resilient body. You’ll learn: • How Modafinil works as a nootropic without overstimulating dopamine • The connection between mitochondria, neuroplasticity, and human performance • Why Modafinil may protect against brain aging and inflammation • How to dose, stack, and cycle Modafinil with supplements and nutrition • What to expect from Modafinil compared to stimulants like Adderall or caffeine • The risks, side effects, and who should avoid it This is essential listening for fans of biohacking, hacking human performance, functional medicine, and longevity who want actionable tools from Host Dave Asprey and a transparent look at the world’s most famous cognitive enhancer. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday (audio-only), and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Modafinil, Armodafinil, Adrafinil, Real Limitless pill, Smart drugs, Eugeroic drug, Nootropics for focus, Orexin activation, Dopamine modulation, Mitochondria ATP production, Neuroplasticity enhancers, Jet lag treatment, ADHD alternative, Poker player focus enhancer, Modafinil stack, Modafinil and L-theanine, Modafinil and NAD+, Modafinil side effects, Stevens Johnson syndrome risk, Alzheimer’s prevention modafinil Thank you to our sponsors! Essentia | Go to https://myessentia.com/dave and use code DAVE for $100 off The Dave Asprey Upgrade. BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 to save 20% off your first order of PerfectAmino. ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. Resources: • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: • 0:00 — Trailer • 1:22 — Origin of Modafinil • 3:48 — Personal Experience • 8:22 — What to Expect • 9:37 — What Is Modafinil • 16:09 — How Modafinil Works • 19:36 — Benefits & Cognitive Upgrades • 25:36 — Dosing, Stacking, and Usage Tips • 28:17 — Side Effects and Safety • 31:37 — Sourcing and Legal Aspects • 36:55 — Research and Future Uses • 42:17 — Stacking for Biohacking • 47:07 — Recap and Final Advice See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 28

Most people are struggling with fat loss, low energy, and hormone chaos—and they don’t even realize the real problem isn’t their diet or workout plan... it’s their liver. In this episode, I break down how your liver controls fat-burning, energy, and hormone regulation—and why things like poor bile flow and mineral deficiencies are sabotaging your results. I’ll show you how to fix your metabolism by targeting the real root cause. This is biohacking 101—backed by science, and built to work. Chapters: 0:00 – Introduction 1:06 – The Liver: Your Metabolic Engine 2:23 – Why Your Detox System is Overwhelmed 3:58 – The 3 Gs That Help Detox Properly 4:15 – The Role of Bile (and Your Gallbladder) 5:48 – Signs of Sluggish Bile Flow 6:43 – How to Get Bile Moving Again 7:18 – Estrogen, Cortisol, and Fat Storage 8:37 – The Real Fix for Hormone Imbalance Connect with Dave Asprey! Website: https://daveasprey.com TikTok: https://www.tiktok.com/@daveaspreyofficial Instagram: https://www.instagram.com/dave.asprey/ Facebook: https://www.facebook.com/Daveaspreyofficial/ X: https://x.com/daveasprey YouTube: https://www.youtube.com/c/daveaspreybpr The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/ Danger Coffee: https://dangercoffee.com/DAVE15 Dave Asprey’s BEYOND Conference: https://beyondconference.com/ Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ Upgrade Collective: https://www.ourupgradecollective.com Upgrade Labs: https://upgradelabs.com 40 Years of Zen: https://40yearsofzen.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 26

Upgrade your week in just 10 minutes with D(AI)ve Asprey’s essential rundown on what matters most in longevity, biohacking, AI health tech, and medical freedom. Each story includes trusted source links—so you can check the facts. This episode covers: - Rapamycin’s Reality Check: A sweeping new review (September 24) finds that the promise of rapamycin for longevity in healthy adults is still weak and inconsistent. Dave shares why lifestyle levers (fasting, protein timing, smart training) come first, and any rapamycin experiment should be clinician-guided and tracked with labs. Source: Aging-US press release – September 24, 2025 and EurekAlert science brief – September 24, 2025 - Senolytics Get Precise: New research (September 23) shows that not all “zombie cells” (senescent cells) are equal in how they respond to anti-aging drugs—so future protocols will be timed and typed, not one-size-fits-all. Source: Aging-US research stream – September 23, 2025 - AI Healthcare: Promise and Pause: The latest market outlook (September 23) says AI in healthcare is surging toward a $100B+ market by 2030, but 70% of doctors still want humans in the loop for diagnosis. Dave shares how to use AI as your copilot—not your captain. Source: Crescendo.ai – September 23, 2025 - Medical Policy Meets Machine Logic: A new federal pilot now lets AI approve or deny Medicare coverage, possibly cutting off therapies before a human review happens. Dave explains how to demand explainability, fair appeals, and human override to protect access. Source: KFF Health News policy rundown – September 25, 2025 - Longevity Headlines You Can Use: Forest bathing wins renewed praise for helping with blood pressure and stress. Northwestern’s SuperAger project links strong social ties to resilient brain health. Human trials now test an antibody therapy to regrow lost teeth. Source: XandroLab Longevity Roundup – Week of Sept 22–25, 2025 Action steps for the week: Try fasting windows and smart protein clustering for mTOR modulation. Let AI help summarize your health data—but get decisions confirmed by your clinician. If you or your family touch Medicare, keep thorough documentation and demand human review. Soak in green spaces, reconnect socially, and watch for cutting-edge therapies. All source links provided for easy reference to the original reporting and research above. This is essential listening for fans of biohacking, hacking human performance, functional medicine, and longevity who want actionable tools from Host Dave Asprey and a guest who embodies what it means to age with energy, clarity, and vitality. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday (audio-only), and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Rapamycin, mTOR modulation, longevity, biohacking, senolytics, zombie cells, AI healthcare, Medicare coverage, human trials, forest bathing, SuperAger, brain health, fasting, protein cycling, medical freedom, anti-aging, personalized medicine, health tech, Dave Asprey, Human Upgrade podcast Thank you to our sponsors! LYMA | Go to https://lyma.sjv.io/gOQ545 and use code DAVE10 for 10% off the LYMA Laser. KILLSwitch | If you’re ready for the best sleep of your life, order now at https://www.switchsupplements.com/ and use code DAVE for 20% off. Resources: • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Intro 0:18 — Rapamycin Hype Check 1:07 — Senolytics Leveled Up 2:41 — AI in Healthcare 3:11 — AI Between You and Your Doctor 5:50 — Three Longevity Angles 7:59 — Outro See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 25

Your mitochondria are the power plants of your cells, and when they break down, you lose energy, brain sharpness, and resilience against aging. In this episode, you’ll learn how to hack your mitochondria to supercharge human performance, prevent decline, and extend longevity with tools that are natural, effective, and backed by decades of research. Watch the condensed video highlight version of this episode (and much more!) on YouTube: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Catharine Arnston, founder of ENERGYbits, recent PhD graduate, and one of the world’s top experts on algae and functional medicine. Entering her 70th year without medications, with the cognition to finish a doctorate, and the health markers of someone decades younger, Catharine is living proof of how mitochondria and nutrition shape aging, brain optimization, and resilience. Together they break down why mitochondria fail after age 30, how algae works as a master supplement to restore superoxide dismutase (SOD) and glutathione, and what happens when you give your cells the nutrients they’re wired to need. They uncover how mitochondria connect to energy, inflammation, metabolism, and cellular resilience. This is a masterclass in hacking energy and longevity, built for people who want to upgrade every system of the body and mind. You’ll learn: • Why mitochondria decline after age 30 and how to stop it • The role of superoxide dismutase (SOD) and glutathione in preventing cellular “rust” • How spirulina and chlorella outperform most supplements for detox and energy • The connection between mitochondria and brain optimization • Why men’s higher iron levels accelerate aging and how algae helps balance it • The real link between metabolism, inflammation, and longevity • How to build a mitochondria-first biohacking stack that actually works This is essential listening for fans of biohacking, hacking human performance, functional medicine, and longevity who want actionable tools from Host Dave Asprey and a guest who embodies what it means to age with energy, clarity, and vitality. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday (audio-only), and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Catharine Arnston, mitochondria, biohacking, algae supplements, spirulina, chlorella, superoxide dismutase, SOD, glutathione, metabolism, longevity, human performance, brain optimization, functional medicine, supplements, neuroplasticity, nootropics, ketosis, fasting, cold therapy, sleep optimization, carnivore, Danger Coffee, Smarter Not Harder, Dave Asprey, Human Upgrade podcast **CTA: Go to www.energybits.com and use code ‘BEYOND’ for a 20% discount** Thank you to our sponsors! HeartMath | Go to https://www.heartmath.com/dave to save 15% off. Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. STEMREGEN | Go to https://stemregen.co/dave25 and use code DAVE25 for 25% off your order. Resources: • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:18 — Intro 3:03 — Longevity & Algae 8:48 — Mitochondria & ATP 13:08 — Free Radicals & SOD 13:18 — Aging After 30 17:18 — Men vs Women in Aging 24:18 — Mitochondrial Breakdown 30:03 — Algae for Mitochondria 37:18 — SOD, Glutathione & Manganese 45:18 — Algae Dosing Tips 51:18 — Processing & Quality 58:18 — Carnivore vs Plants 1:00:48 — Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 23

Your brain isn’t as rational as you think, and that blind spot can wreck your decision-making, relationships, and even your health. In this episode, you’ll learn how to spot the hidden cognitive traps that even the smartest people fall for, and how to upgrade your thinking so you can perform better, live longer, and make choices that actually serve you. Watch the condensed video highlight version of this episode (and much more!) on YouTube: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Steven Pinker, a world-renowned cognitive psychologist, Harvard professor, and bestselling author whose research reshaped how we understand language, bias, social norms, and rationality. Pinker’s decades of scholarship make him a trusted guide to the mechanics of the mind and the behaviors that either elevate or derail human performance and longevity. Together they break down how the brain actually reasons, why smart people still fall for tribal thinking, what current AI gets wrong about human intelligence, and how “common knowledge” quietly governs cooperation, law, and civility. This is a masterclass in brain optimization through better thinking, built for people who care about biohacking, hacking mental models, neuroplasticity, and high-performance decision-making. You’ll learn: • How to recognize and counter the “my-side bias,” even if you’re highly intelligent • Why common knowledge creates and sustains social norms and coordination • The art of indirect speech and tact, and how to calibrate your words to reduce social risk • Simple upgrades that make video calls feel closer to real eye contact and why that boosts trust • What today’s AI gets wrong about minds and why models hallucinate • Rational habits that work in the real world: steelmanning, probabilistic thinking, adversarial collaboration, and making bets as a tax on bad arguments • Why liberal democracy fits human nature better than autocracy and how norms erode or hold • How to rebuild face-to-face social skills in a screen-first culture to improve resilience and performance This is essential listening for fans of biohacking, brain optimization, human performance, neuroplasticity, and longevity who want clear, usable frameworks to think better and live better with Dave Asprey. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday (audio-only), and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Steven Pinker, cognitive psychology, rational thinking, my-side bias, human nature, common knowledge, cognitive bias, AI and human intelligence, democracy and human behavior, social norms psychology, decision-making hacks, brain optimization, biohacking the mind, mental performance, neuroplasticity, rationality movement, bias and longevity, functional intelligence, Human Upgrade podcast, Dave Asprey, thinking traps, steelmanning, epistemic humility, outrage economy, psychology of power, critical thinking upgrade, hacking human performance Thank you to our sponsors! KILLSwitch | If you’re ready for the best sleep of your life, order now at https://www.switchsupplements.com/ and use code DAVE for 20% off. Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. **Order Steven’s new book WHEN EVERYONE KNOWS THAT EVERYONE KNOWS...: COMMON KNOWLEDGE AND THE MYSTERIES OF MONEY, POWER, AND EVERYDAY LIFE: HTTPS://TINYURL.COM/V685EVZR Resources: • Steven’s Website: https://stevenpinker.com/ • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 0:59 — Introduction 1:58 — Human Nature 3:30 — Cognitive Psychology 5:46 — Academia Path 7:32 — Canada vs. U.S. 8:42 — College Value 12:08 — Curiosity 15:25 — Government & Humans 19:56 — AI & Cognition 24:45 — Fairness & Justice 32:56 — Social Norms 47:12 — Communication Skills 55:32 — Virtual Society 57:20 — Personal Biases See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 21

If you feel like your brain's stuck in first gear, losing focus, forgetting simple things, feeling mentally sluggish—you’re not alone. I lived with brain fog for 15 years while building companies in Silicon Valley, and no productivity hack or double espresso fixed it. In this episode, I’ll show you how to clear brain fog at the cellular level by restoring mitochondrial energy, ditching brain-damaging foods, optimizing sleep, and upgrading your nutrition. These are the exact science-backed steps that got me back to feeling sharp, focused, and fully me. Let’s turn your brain back on. Chapters: 0:00 – Introduction 0:49 – The Root Cause of Brain Fog 1:26 – What Most People Get Wrong 2:20 – How to Fix Your Mitochondria 2:57 – Food: Fuel or Poison 4:48 – The 4 Brain Poisons Killing Your Focus 5:20 – Exercise for Brain Energy (Not Burnout) 7:55 – Brain Fog Supplements That Work Brain fog supplement: https://shopsuppgradelabs.com/products/brain-101, use code DAVE15 Connect with Dave Asprey! Website: https://daveasprey.com TikTok: https://www.tiktok.com/@daveaspreyofficial Instagram: https://www.instagram.com/dave.asprey/ Facebook: https://www.facebook.com/Daveaspreyofficial/ X: https://x.com/daveasprey YouTube: https://www.youtube.com/c/daveaspreybpr The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ and https://m.facebook.com/Thehumanupgrade/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 19

Confidence is biology you can hack. In this episode, you’ll see how confidence builds inside your brain, rewires through neuroplasticity, and connects directly to mitochondria, metabolism, and human performance. You’ll get tools that reprogram fear, regulate your nervous system, and turn stress into fuel so you build radical confidence that lasts. Listen to this classic with host Dave Asprey as he talks with entrepreneur, author, and Women of Impact founder Lisa Bilyeu. Lisa went from a stay-at-home “supporting role” to co-founding Quest Nutrition, scaling it into a billion-dollar company, and running a global media empire. She brings years of lived experience and applied mindset training, making her one of the most authentic voices on confidence, resilience, and leadership in the biohacking world. You’ll learn how to: • Hack confidence with the same strategies you use for sleep optimization, fasting, and cold therapy • Spot biological triggers behind fear, self-doubt, and procrastination • Use repetition and mindset tools to upgrade brain optimization and neuroplasticity • Turn stress hormones into growth signals for longevity and functional medicine practices • Reframe trauma and setbacks as power for resilience and high performance • Support courage and focus with nootropics, ketosis, supplements, and Danger Coffee This episode shows you how to treat confidence as a trainable skill, not a personality trait. If you want smarter not harder strategies to master your biology, expand your impact, and live with unshakable resilience, you’ll find them here. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes release every Tuesday, Thursday, Friday (audio-only), and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Lisa Bilyeu, Radical Confidence, Quest Nutrition, Women of Impact, confidence training, resilience biohacking, mindset reprogramming, courage hacking, fear rewiring, entrepreneurial mindset, human performance, brain optimization, neuroplasticity tools, mitochondria and confidence, trauma resilience, emotional regulation, nootropics for confidence, stress as fuel, leadership confidence, Human Upgrade podcast Thank you to our sponsors! EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE for 40% off. Resources: • Lisa’s Website: https://lisabilyeu.com/ • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 – Trailer 0:38 – Intro 2:38 – From Housewife to Entrepreneur 17:52 – Building Impact Theory 27:56 – Radical Confidence 39:14 – The No BS Game 44:45 – Finding Purpose 55:34 – Inner Critic & Competence 1:01:10 – Becoming Your Own Hero 1:08:32 – Boundaries & Relationships 1:09:52 – Conclusion See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 18

If you’ve ever cringed at the sound of your own voice or struggled to hold attention in a room, this episode will change the way you speak and how others respond to you. You’ll discover how vocal tone, breath, and emotion act as biological levers you can train to improve your health, extend your longevity, and build magnetic charisma. Watch the condensed video highlight version of this episode (and much more!) on YouTube: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Roger Love , the celebrity voice coach who trained Bradley Cooper, Tony Robbins, Selena Gomez, and Brendon Burchard. Roger has spent decades teaching actors, executives, and performers how to master their voice to create influence and impact. In this conversation, he shares the science behind vocal tone and the emotional cues hidden in your breath. You’ll hear why most people speak from the wrong part of the body and how that drains power from every interaction. You’ll learn how digital habits dull your voice, which techniques make you sound more confident and trustworthy, and why sound can heal the nervous system. Dave and Roger also explore how voice training supports your biology, boosts emotional control, and protects your performance as you age. This episode gives you tools to speak with more authority, connect on a deeper level, and improve your health through one of your most underused systems: your voice. If you want to lead, perform, persuade, or simply feel heard, this conversation shows you how to upgrade the way you sound—and how you feel when you speak. You’ll learn: • Why most people speak from the wrong part of their body • How your voice shapes the way others feel about you • The link between vocal tone, breathing, and nervous system health • How to sound more confident, persuasive, and emotionally resonant • Why digital habits are weakening your communication • How to train your voice as a powerful analog biohack for longevity Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes release every Tuesday, Thursday, Friday (audio-only), and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Roger Love, voice coach, Bradley Cooper, vocal tone training, voice confidence, charisma training, sound healing, biohacking voice, emotional resonance, public speaking, vocal mastery, breathwork, mitochondria and voice, analog biohacking, vocal optimization, high performance communication, voice training for health, Tony Robbins voice, Human Upgrade podcast Thank you to our sponsors! BodyGuardz | Visit https://www.bodyguardz.com/ and use code DAVE for 25% off. STEMREGEN | Go to https://stemregen.co/dave25 and use code DAVE25 for 25% off your order. Caldera + Lab | Go to https://calderalab.com/DAVE and use code DAVE at checkout for 20% off your first order. **If you're interested in Voice Training, go to www.rogerlove.com/dave and use code DAVE for $50 off** Resources: • Roger’s Website: www.rogerlove.com/dave • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: • 0:00 – Trailer • 1:30 – Intro • 1:48 – Meet Roger Love • 3:22 – Nature vs. Nurture • 5:46 – Speaking vs. Singing • 7:02 – Breathing & Voice Health • 13:35 – Voice & Attractiveness • 19:13 – Stuttering & Vocal Disorders • 24:51 – Emotional Speaking • 29:04 – Mastery & Finding Your Voice • 39:55 – Voice & Technology • 49:20 – Becoming AI-Proof • 56:29 – Emotion & Sound • 1:04:30 – Stage Fright & Tone Deafness • 1:08:00 – Voice Training Tips See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 16

If you’ve ever felt crushed by stress or trapped by fear, this episode gives you the science and strategies to break free. You’ll learn how Olympic-level coaching can rewire your brain for resilience, unlock peak human performance, and extend your longevity through proven biohacking tools. Watch the video highlight version of this episode (and much more!) on YouTube: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Jim Murphy, a former professional baseball player turned Olympic coach and now bestselling author of Inner Excellence . Jim has spent decades training world-class athletes and high performers to master their mindset, expand neuroplasticity, and build the courage to thrive under pressure. His work blends psychology, functional medicine, and elite coaching to help people overcome fear, reframe failure, and step into their highest potential. Together, they explore the inner game of stress mastery: why fear lives in your mitochondria, how shame and guilt sabotage performance, and how to turn setbacks into resilience. They also discuss supplements that improve metabolism, why childlike wonder fuels longevity, and how to use practical biohacking to cultivate courage. This is essential listening for anyone serious about hacking fear, upgrading resilience, and living the smarter not harder way. Whether you’re chasing athletic greatness, leading at the highest level, or just seeking more freedom in daily life, these strategies show you how to unlock love over fear and achieve lasting longevity. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, Friday (audio-only), and Sunday (BONUS) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: inner excellence, Jim Murphy, Olympic coach, fear hacking, stress mastery, resilience training, courage mindset, shame vs guilt, brain optimization, neuroplasticity, mitochondria stress, childlike wonder, longevity habits, emotional resilience, high performance, mindset coaching, presence training, love over fear, functional medicine, stress recovery, AJ Brown, AJ Brown book, Eagles football player book, NFL sidelines book Thank you to our sponsors! LYMA | Go to https://lyma.sjv.io/gOQ545 and use code DAVE10 for 10% off the LYMA Laser. BON CHARGE | Go to https://boncharge.com and use code DAVE for 15% off. ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order Resources: • Jim’s Website: https://innerexcellence.com/ • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:30 — Intro 3:10 — Subconscious Mind and Fear 4:36 — Purpose Beyond Results 6:38 — Writing Inner Excellence 10:16 — Redefining Mental Toughness 14:11 — Guilt and Shame 18:24 — Embracing Fear and Challenge 23:50 — Teaching Kids and Modeling Behavior 31:44 — Childhood Programming and Performance 45:59 — Living Fully, Ready to Die ??:?? — Maintaining Childlike Wonder See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 14

Most men think declining testosterone is just “part of aging”, but that’s a lie Big Pharma sold you. In this video, I break down exactly how I raised my testosterone in my 50s without injections, drugs, or TRT. These are the same biohacks I used to turn my energy, drive, and strength around, naturally. I’ll walk you through how your diet, your sleep, and even the light in your bedroom could be sabotaging your hormones. Want results? Start here. Chapters: 0:00 – Introduction 1:40 – The Lie About Aging and Testosterone 2:49 – What’s Desatroying Your Testosterone Daily 3:42 – How Your Cells Actually Make Testosterone 4:58 – Why Diet is Step One (and What to Eat) 7:08 – The Most Underrated T Booster 8:38 – The Truth About Light and Hormones 14:40 – How to Fix It Get Your Oral Testosterone Here: http://www.LiveThrive.co/asprey Connect with Dave Asprey! Website: https://daveasprey.com TikTok: https://www.tiktok.com/@daveaspreyofficial Instagram: https://www.instagram.com/dave.asprey/ Facebook: https://www.facebook.com/Daveaspreyofficial/ X: https://x.com/daveasprey YouTube: https://www.youtube.com/c/daveaspreybpr The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ and https://m.facebook.com/Thehumanupgrade/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 12

Want to biohack your biology with nature’s most powerful anti-aging compounds? In this episode, you’ll discover how medicinal mushrooms fuel neurogenesis, protect mitochondria, supercharge immunity, and even help save the planet’s pollinators. From sharper focus and deeper REM sleep to protecting DNA from oxidative stress, fungi are the ultimate biohacking tools for performance, resilience, and longevity. Watch episodes on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR (Re-run) Host Dave Asprey sits down with legendary mycologist and author Paul Stamets and mushroom entrepreneur Julian Mitchell. Together, they uncover the science of fungi as medicine — how mushrooms repair nerves, fight viruses, act as prebiotics for your microbiome, and provide the ultimate anti-aging biohacks. You’ll also hear how fungi hold the key to saving pollinators, regenerating soil, and extending human longevity. You’ll Learn: • Which anti-aging compounds in mushrooms protect your mitochondria and DNA • How lion’s mane stimulates nerve growth factor and improves memory, focus, and REM sleep • Why oyster mushrooms may help fight flu viruses and reduce chronic inflammation • How mushroom tinctures unlock more bioactive compounds than powders or capsules • The surprising role fungi play in saving bees and restoring environmental balance Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: anti-aging mushrooms, Paul Stamets fungi, lion’s mane memory, mushroom tincture benefits, ergothionine mitochondrial protection, oyster mushroom flu prevention, reishi immune system, cordyceps endurance, turkey tail microbiome, medicinal mushroom research, fungi save the bees, chaga antioxidants, mushroom longevity biohack, mycelium networks, functional mushrooms anti-inflammatory, mushroom brain health, neurogenesis fungi, adaptogenic mushrooms, mushroom cooking bioavailability • Lifecykel Mushroom Products - use code ‘DAVE20’ for 20% off: https://www.lifecykel.com/?rfsn=4497217.61b030&utm_source=refersion&utm_medium=affiliate&am… • Paul Stamets’ Website: https://hostdefense.com/ Thank you to our sponsors! • ECHO Water | Go to http://echowater.com/dave and use code DAVE10 for 10% off your ECHO Flask. Resources: • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: • 0:00 — Trailer • 0:47 — Intro • 6:15 — Mushrooms vs. Algae • 10:21 — Mushroom Safety & Microbiome • 12:24 — Mushrooms as Medicine • 14:43 — Psychedelics & Microdosing • 16:26 — Kakadu Plum & Prebiotics • 18:07 — Oyster Mushrooms & Cooking • 21:35 — Mushrooms & Bees • 25:59 — Lion’s Mane & Chaga See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 11

Want to improve memory, unlock neuroplasticity, and achieve sharper brain optimization? This episode reveals how Transcendental Meditation (TM) functions as one of the most powerful nootropics for human performance, longevity, and resilience. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with neuroscientist and physician Dr. Tony Nader , the global leader of the Transcendental Meditation movement. With an MD and PhD from MIT and Harvard, Dr. Nader bridges hard science with ancient wisdom, showing how TM measurably changes brainwaves, boosts mitochondria, and even slows biological aging. His research connects meditation to reduced stress, faster reaction time, and improved memory, giving listeners cutting-edge tools for smarter not harder living. You’ll Learn: • How Transcendental Meditation induces high-coherence alpha brain states that improve clarity, focus, and resilience • Why TM increases blood flow to the prefrontal cortex and supports memory, decision-making, and creativity • How meditation measurably reduces biological age by 5–10 years through stress reduction and physiological balance • Why reaction time and situational awareness improve immediately after meditation — even used by fighter pilots • How TM differs from mindfulness or concentration practices at the brainwave level (alpha vs. theta vs. gamma) Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: Transcendental Meditation benefits, Tony Nader MIT neuroscientist, TM brainwaves alpha coherence, Meditation and neuroplasticity, Default mode network meditation, Meditation and mitochondria, TM and biological age, Consciousness and quantum field theory, Meditation vs psychedelics, Meditation and intuition training, Meditation and dopamine, TM reaction time studies, Hippocampus meditation memory, TM and functional medicine, Meditation and metabolism, Meditation and PTSD recovery, TM for sleep optimization, Meditation and fasting stack, TM and human performance, Meditation and longevity research Thank you to our sponsors! Business of Biohacking Summit | Apply to The Business of Biohacking Summit https://businessofbiohacking.com/ . fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Resources: • Tony’s Website: https://drtonynader.com/ • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:47 — Intro 2:57 — Transcendental Meditation 3:56 — States of Consciousness 10:16 — Brainwaves & Practice 18:35 — Science Bias 38:07 — Mind & Reality 50:32 — Psychedelics & TM 54:29 — Brain & Body Effects 59:31 — Daily Practice 1:02:43 — Closing Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 9

Most people spend their lives trying to outrun death instead of learning from it. This episode shows you why facing mortality directly can unlock resilience, forgiveness, gratitude, and peace while upgrading longevity, human performance, and even brain optimization. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Suzanne O’Brien, RN—an end-of-life expert, hospice nurse, and founder of Doulagivers who has guided over 1,000 people through their final moments. She shares what the dying can teach the living about biohacking fear, letting go of unresolved trauma, and finding clarity before it’s too late. Together they explore how hacking your mindset around death transforms not only emotional well-being but also physical health, neuroplasticity, and metabolism. You’ll hear stories of people who discovered forgiveness and gratitude at the end of life, and how those practices directly influence mitochondria, sleep optimization, and longevity. They dive into the link between fear, stress chemistry, and chronic illness—and why tools like fasting, ketosis, cold therapy, supplements, nootropics, and functional medicine create the inner and outer resilience needed to face life fully. You’ll Learn: • Why fear of death silently undermines health, performance, and human potential • How forgiveness and gratitude rewire neuroplasticity and boost brain optimization • What hospice nurses know about consciousness and near-death experiences that science is only starting to confirm • How unresolved trauma shows up as physical pain and disease at the end of life Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: fear of death, hospice nurse, doulagivers, end of life planning, good death, forgiveness practice, gratitude science, near death experience, hospice care stories, emotional trauma release, spiritual awakening, conscious dying, home funeral, palliative care, death doula training, legacy planning, end of life rituals, soul agreements, dying process stages, compassionate care Thank you to our sponsors! ECHO Water | Go to http://echowater.com/dave and use code DAVE10 for 10% off your ECHO Flask. Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 to save 20% off your first order of PerfectAmino. Resources: • Suzanne’s Website: https://suzannebobrien.com/ • Get Suzanne's Book 'The Good Death': https://thegooddeathbook.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 00:00 — Trailer 01:05 — Introduction 03:13 — End-of-Life Choices 09:50 — Forgiveness & Suffering 15:46 — Advice to Younger Self 20:00 — What Makes a Good Death 23:00 — Hospice Stories & Mystical Experiences 33:05 — The Good Death Defined 41:01 — Meaning & Purpose See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 5

What if the foods you think are healthy are actually disrupting your biology? From sugar marketed as a performance tool to “whole grains” that drive cravings, this episode uncovers how hidden traps in modern nutrition can hijack your brain, wreck your metabolism, and accelerate aging. You’ll learn how to rethink daily eating so it fuels energy, resilience, and long-term health instead of quietly sabotaging it. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Max Lugavere, health journalist, filmmaker, and bestselling author of Genius Foods and The Genius Kitchen . Max is one of the most trusted voices in nutrition and functional medicine, translating complex science into practical tools you can use right now. His work has been featured on The Today Show , PBS , and across global media for helping people reclaim health through smarter food and lifestyle choices. In this re-run, Dave and Max break down the real impact of sugar, salt, and food processing on your brain and body. They explore how cooking methods change health outcomes, when fasting and ketosis become powerful tools, and why supplements, nootropics, and trace minerals fill gaps in the modern diet. They also tackle controversial topics like carnivore diets, cold therapy, and whether “healthy” plant-based foods are truly supporting resilience—or quietly eroding it. You’ll Learn: • The biggest nutrition myths that silently damage health and performance • How sugar can act as both poison and fuel depending on context • Why cooking methods make the difference between nourishment and toxicity • The overlooked role of minerals, supplements, and culinary literacy • How nootropics, cold therapy, and sleep optimization reset your brain • Why some “health foods” accelerate aging instead of protecting you • The truth about carnivore diets, industrial farming, and sustainability • When fasting, ketosis, and carb cycling create optimal results This episode gives you a science-backed blueprint to hack your nutrition, sharpen your brain, and extend your longevity with foods that truly support your biology. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: uric acid longevity, uric acid metabolism, fructose uric acid pathway, xanthine oxidase inhibition, quercetin uric acid, luteolin supplements, AMP kinase uric acid, AMP deaminase metabolism, uric acid and mitochondria, uric acid and neuroplasticity, uric acid Alzheimer’s risk, uric acid dementia prevention, uric acid and nitric oxide, fructose metabolism hibernation biology, evolutionary mismatch uricase mutation, fructokinase inhibition, uric acid and insulin resistance, gout biohacking, uric acid and obesity, uric acid functional medicine Resources: • Max’s Website: https://www.maxlugavere.com/ • Screenfit | Get your at-home eye training program for 40% off using code DAVE https://www.screenfit.com/dave • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 0:30 — Introduction 1:51 — Resilience & Stress 2:41 — Food Philosophy 6:20 — Sugar & Metabolism 11:21 — Fructose & Flexibility 21:57 — Big Food & Morality 24:51 — Meat & Sustainability 26:30 — Cooking at Home 28:34 — Salt & Minerals 30:07 — Dietitians & Industry 32:45 — Intuitive Eating 41:13 — Cooking Risks 45:26 — Fish & Contaminants 49:16 — Lectins & Sensitivities 52:22 — Herbs & Spices 54:59 — Recipes & Highlights 58:17 — Closing See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 4

Most people think broccoli is a superfood, but the reality is more nuanced. In this episode of The Human Upgrade , Host Dave Asprey explores the good and bad of broccoli—why adult broccoli can block thyroid function and cause gut issues, while broccoli seeds deliver sulforaphane, the powerful compound that activates all three of your body’s detox pathways. You’ll learn how sulforaphane protects against glyphosate, repairs leaky gut, and upgrades mitochondria, metabolism, and longevity. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Dave is joined by two Johns Hopkins–trained researchers whose expertise in biohacking, biochemistry, and functional medicine makes them trusted leaders in the field. Together they reveal how sulforaphane, berberine, curcumin, and alpha-lipoic acid outperform bulk vegetables and even rival GLP-1 weight loss drugs—delivering natural ways to improve metabolism, regulate dopamine, and protect the brain. Their research shows how targeted supplements can boost neuroplasticity, brain optimization, and human performance without the side effects of pharmaceuticals. Dave and his guests break down why bulk vegetables don’t deliver enough beneficial compounds, how to hack plant toxins for maximum benefit, and why supplement stacks often outperform carnivore, vegan, or high-vegetable diets for long-term health. You’ll discover how biohacking tools like fasting, ketosis, nootropics, cold therapy, and sleep optimization amplify these compounds for smarter not harder living. You’ll Learn: • Why adult broccoli can disrupt thyroid function while broccoli seeds fuel detox and longevity • How sulforaphane, berberine, curcumin, and alpha-lipoic acid support metabolism and mitochondria • Why natural compounds can rival GLP-1 drugs for weight loss and energy regulation • The connection between glyphosate, leaky gut, inflammation, and brain fog • How to stack supplements with fasting, ketosis, and cold therapy for brain optimization • Why functional medicine and biohacking provide better long-term solutions than fad diets • The smarter not harder way to extract benefits from plants without the toxic load This episode is essential for anyone serious about biohacking, upgrading metabolism, extending longevity, and achieving high performance with resilience and clarity. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: sulforaphane supplements, broccoli seed extract, detox pathways phase 1 2 3, NRF2 activation, glyphosate gut health, leaky gut repair biohacking, thyroid blockers broccoli, DIM I3C compounds, functional medicine detox, Johns Hopkins biohacking research, berberine metabolism, alpha lipoic acid mitochondria, curcumin weight loss, GLP-1 natural alternatives, dopamine metabolism regulation, neuroplasticity supplements, fasting and sulforaphane, ketosis and detox synergy, smarter not harder supplements, Dave Asprey broccoli Mara Labs Website: https://mara-labs.com/Dave for 28% off! Resources: -Mara Labs Website: https://mara-labs.com/Dave for 28% off! -BrocElite link: https://partnerships.mara-labs.com/4H6KD28/TZW7X/?&sub4=biohack&uid=123 -GLPerfect link: https://partnerships.mara-labs.com/4H6KD28/TZW7X/?&sub4=biohack&uid=123 Thank you to our sponsors! EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE for 40% off. Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Calroy | Head to https://calroy.com/dave for an exclusive discount. Resources: • Mara Labs Website: NEED TO INSERT CODE • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 00:00 — Trailer 01:10 — Introduction 01:49 — Broccoli Benefits & Risks 09:24 — Plant Toxins & Modern Diet 12:56 — Mold Detox Experiences 18:30 — Mycotoxins, Glyphosate & Gut Health 26:20 — Metabolic Syndrome & Endotoxins 35:44 — Timing Sulforaphane for Glyphosate Protection 39:35 — Weight Loss & GL Perfect 49:19 — Personalization & Supplement Stacking 55:10 — Sleep, Ketosis & Berberine 58:30 — Alpha Lipoic Acid + Berberine Synergy 1:01:00 — Natural Alternatives to GLP-1 Drugs See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 2

Millions of people are living with unexplained symptoms like allergies, brain fog, anxiety, and chronic fatigue without realizing the hidden cause: mast cells gone rogue. In this episode of The Human Upgrade , Host Dave Asprey sits down with leading functional medicine physician Dr. Tania Dempsey to uncover how Mast Cell Activation Syndrome (MCAS) drives inflammation, disrupts mitochondria, and sabotages metabolism—and what you can do to switch it off. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Dr. Dempsey is internationally recognized for her work in functional medicine, biohacking, and chronic illness. She co-founded the AIM Center for Personalized Medicine, has published groundbreaking research on MCAS with Dr. Lawrence Afrin, and treats some of the most complex cases of immune dysregulation, autoimmune disease, and environmental illness. Her expertise helps you understand why mast cells are the missing link in allergies, long COVID, Lyme, mold toxicity, and even hormone disruption—and how to reclaim control of your biology. Dave and Dr. Dempsey break down how mast cells interact with mitochondria, hormones, and the nervous system, showing how chronic inflammation accelerates aging and blocks human performance. You’ll discover why biohacking tools like fasting, ketosis, supplements, red light, cold therapy, sleep optimization, and smarter not harder lifestyle strategies all influence mast cell stability. They also explore why brain optimization, neuroplasticity, and nootropics are essential for calming inflammatory cascades, and how functional medicine provides practical solutions beyond conventional treatment. You’ll Learn: • Why mast cells are the hidden switch behind allergies, chronic inflammation, and brain fog • How mitochondria and mast cells work together to drive human performance—or disease • The connection between toxic mold, Lyme, long COVID, hormone imbalance, and MCAS • How supplements, fasting, ketosis, and cold therapy stabilize mast cells and boost longevity • Why functional medicine and biohacking are essential for complex chronic illness • How mast cells impact metabolism, sleep optimization, and neuroplasticity • The surprising link between mast cells, anxiety, and mental health symptoms This episode is essential for anyone serious about hacking inflammation, protecting longevity, upgrading metabolism, and achieving high performance with resilience and clarity. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: mast cell activation syndrome, MCAS, chronic inflammation, mitochondria dysfunction, histamine intolerance, functional medicine, biohacking, allergies, brain fog, long covid, mold toxicity, Bartonella, Lyme co-infections, oxalates, salicylates, mast cell stabilizers, immune dysregulation, neuroinflammation, chronic fatigue syndrome, autoimmune triggers, personalized medicine, longevity supplements Thank you to our sponsors! Leela Quantum Tech | Head to https://leelaq.com/DAVE for 10% off. LMNT | Free LMNT Sample Pack with any drink mix purchase by going to https://drinklmnt.com/DAVE . Resources: • Tania’s Website: https://drtaniadempsey.com/ • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 00:00 — Trailer 01:10 — Introduction 03:27 — Why So Sick Today? 05:57 — MCAS Explained 08:33 — Mold & Environment 11:36 — Spotting MCAS 13:43 — Personal Stories 15:15 — Research & Biohacking 16:35 — Managing Triggers 20:15 — Gut & Stomach Acid 22:42 — Reaction Timing 25:30 — Hormones & MCAS 28:39 — Thyroid & Mitochondria 32:28 — Chronic Illness Navigation 40:06 — Insurance Battles 44:44 — Cholesterol & Ethics 49:11 — Personalized Care 53:24 — Circadian & Stress 58:24 — Testing Approaches 01:01:35 — Collagen & Joints 01:04:34 — MMPs & Aging 01:09:12 — Access & Experimentation 01:13:14 — MCAS & Mental Health 01:17:46 — Benzos & Stigma 01:20:23 — Vaccines & Spike Protein 01:25:18 — Research & Treatments 01:26:12 — Nicotine & Focus 01:29:24 — Closing See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 29

Most people track glucose or ketones, but almost no one is measuring the hidden signal that could be silently wrecking your metabolism, brain function, and longevity: uric acid. This episode reveals why this overlooked biomarker drives obesity, diabetes, cardiovascular disease, Alzheimer’s, and even accelerated aging—and how you can hack it to unlock resilience, human performance, and smarter not harder health upgrades. Watch the podcast on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR We revisit host Dave Asprey sitting down with Dr. David Perlmutter, one of the world’s leading functional medicine neurologists and the #1 New York Times bestselling author of Grain Brain and Drop Acid . Dr. Perlmutter has spent decades connecting gut health, brain optimization, and neuroplasticity with lifestyle interventions that truly change the trajectory of disease. In this conversation, he explains how uric acid acts as a metabolic switch that determines whether you burn fat or store it, whether your mitochondria power you up or slow you down, and whether your brain stays sharp or declines with age. They break down how fructose, purines, alcohol, and even dehydration spike uric acid, why Japan is decades ahead in using this as a health marker, and how supplements like quercetin and luteolin rival pharmaceuticals in keeping it under control. You’ll also learn how ketosis, fasting, cold therapy, carnivore and plant-based approaches, and sleep optimization all interact with uric acid to shape your healthspan. This is biohacking at its most actionable—because once you measure this signal, you can control it, and once you control it, you radically upgrade your metabolism, your brain, and your longevity. This is essential listening for anyone serious about hacking their biology, building neuroplasticity, powering up mitochondria, exploring nootropics, and discovering smarter not harder ways to live longer and perform better. You’ll Learn: • Why uric acid may be the most important overlooked biomarker for longevity • How it connects obesity, diabetes, cardiovascular disease, and Alzheimer’s • The evolutionary reason your body uses uric acid as a survival signal • How fructose and hidden sugars sabotage metabolism and brain optimization • The role of quercetin, luteolin, and targeted supplements in lowering uric acid • Why measuring at home with a simple device can change your health trajectory • How functional medicine uses uric acid as a predictive tool for chronic disease Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: uric acid longevity, uric acid metabolism, fructose uric acid pathway, xanthine oxidase inhibition, quercetin uric acid, luteolin supplements, AMP kinase uric acid, AMP deaminase metabolism, uric acid and mitochondria, uric acid and neuroplasticity, uric acid Alzheimer’s risk, uric acid dementia prevention, uric acid and nitric oxide, fructose metabolism hibernation biology, evolutionary mismatch uricase mutation, fructokinase inhibition, uric acid and insulin resistance, gout biohacking, uric acid and obesity, uric acid functional medicine Resources: • David’s Website: https://drperlmutter.com/ • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 0:35 — Introduction 2:26 — Why Uric Acid Matters 5:55 — Measuring Uric Acid 8:17 — Disease Risk 9:38 — Metabolism Disruption 15:59 — What Raises Uric Acid 26:20 — Global Research 29:50 — Gut & Inflammation 32:55 — Seasonal Eating 47:36 — Brain Health 56:38 — Supplements & Testing 61:45 — The LUV Diet 71:41 — Closing Insights See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 28

Your dopamine system is being hijacked every day, and the way to reclaim it might surprise you. This episode reveals how pain, pleasure, and addiction are wired in your brain, and how to use that knowledge for real brain optimization, resilience, and longevity. You’ll discover why your dopamine levels control motivation, focus, mood, and even cravings—and the science-backed strategies that reset your neuroplasticity, metabolism, and reward system. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Dr. Anna Lembke, Stanford psychiatrist and bestselling author of Dopamine Nation . She is one of the world’s leading experts on addiction, compulsive behavior, and the neuroscience of reward pathways. With decades of clinical work and groundbreaking research, she explains why dopamine has become the modern lens for understanding desire, distraction, and dysfunction—and how we can hack it to upgrade human performance. They break down how dopamine drives addiction, why pain can reset your reward system, and how simple practices like fasting, cold therapy, and supplements affect your brain chemistry. You’ll learn how nicotine, GLP-1 drugs, and even nootropics alter dopamine sensitivity, and why overstimulation from social media, pornography, and ultra-processed food is creating an epidemic of anhedonia. The conversation also covers how functional medicine and biohacking can protect your mitochondria, restore your natural dopamine balance, and make your brain more resilient. You’ll Learn: • Why dopamine itself is not addictive—and what really drives addiction • How pain, hormesis, and “dopamine fasting” can reset your reward system • Why social media and digital overstimulation create chronic dopamine deficit states • The role of GLP-1 drugs, nicotine, psychedelics, and other substances in rewiring dopamine • How functional medicine and supplements help restore dopamine balance • The connection between dopamine, mitochondria, fasting, cold therapy, and longevity • Why radical honesty and self-binding are powerful anti-addiction hacks This is essential listening for anyone serious about hacking dopamine for better focus, sleep optimization, metabolism, and long-term brain health. Whether you’re curious about the link between dopamine and neuroplasticity, looking to upgrade human performance with smarter not harder tools, or just want to know how to stop dopamine hijacks from ruling your life, this episode gives you the science and strategies you need. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: dopamine fasting, pleasure-pain balance, dopamine deficit state, addiction neurobiology, anhedonia treatment, dopamine receptors, neuroadaptation gremlins, endogenous opioids, cold plunge dopamine, hormesis neuroscience, nucleus accumbens dopamine, L-Dopa addiction, GLP-1 and dopamine, social media addiction neuroscience, dopamine reward pathway, compulsive behavior psychiatry, dopamine and neuroplasticity, anhedonia supplements, functional medicine addiction, dopamine repair party Thank you to our sponsors! Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. Resources: • Anna’s Website: https://www.annalembke.com/ • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:10 — Introduction 5:47 — Pleasure–Pain Balance 6:45 — Homeostasis & Adaptation 8:22 — Addiction & Dopamine Deficit 10:14 — BICEP: Conscious Pain Exposure 14:26 — Adapting to Pleasure & Pain 20:20 — GLP-1s and Joy 21:39 — Modern Anhedonia 34:32 — Resilience in Young People 42:00 — Social Media & Mental Health 44:46 — Control & Addiction 55:14 — Dopamine Fasting 1:03:18 — Self-Binding Tools 1:07:56 — Psychedelics & Addiction 1:12:25 — Parenting in the Digital Age 1:14:39 — Progress & Outlook See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 26

Alzheimer’s is not inevitable—and it may even be optional. In this groundbreaking episode, you’ll learn how to prevent, slow, and in some cases reverse cognitive decline using strategies that also enhance brain optimization, metabolism, and longevity. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey is joined by Dr. Dale Bredesen, a world-renowned neurologist and leading Alzheimer’s researcher who has published over 240 peer-reviewed papers. Dr. Bredesen has spent decades proving that Alzheimer’s is not a one-pathway disease but a network failure driven by inflammation, toxins, and mitochondrial dysfunction. His protocol has helped thousands of patients regain memory, extend healthspan, and reclaim brain performance. Together, they unpack how biohacking tools like fasting, ketosis, supplements, sleep optimization, cold therapy, and functional medicine can rewire neuroplasticity, protect mitochondria, and keep the brain in “connection mode” instead of decline. You’ll hear why the pharmaceutical industry resists these solutions, how toxins like Paraquat and mold fuel cognitive decline, and what young people can do right now to bulletproof their brains for life. This episode is essential listening if you care about hacking human performance, upgrading metabolism, or extending longevity. You’ll walk away with practical strategies you can use today—whether that means optimizing your mitochondria with nootropics, strengthening resilience with smarter not harder recovery, or fueling your brain with Danger Coffee. You’ll Learn: • Why Alzheimer’s can begin as early as your 20s and what biomarkers to track • The seven major drivers of Alzheimer’s and how to reverse them with biohacking strategies • How APOE4 genetics, toxins, and inflammation accelerate brain aging—and what to do about it • The role of mitochondria, ketosis, and fasting in restoring brain optimization and neuroplasticity • Why prevention is exponentially easier than reversal and the top three actions you should start in your 20s • How to avoid “learned helplessness” in medicine and reclaim control over your brain span and longevity Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: Alzheimer’s prevention biohacking, APOE4 genetics risk, mitochondrial dysfunction brain, network insufficiency model, cognitive decline reversal protocol, neuroplasticity longevity strategies, mild cognitive impairment treatment, subjective cognitive impairment biomarkers, ketoflex 12/3 diet, mycotoxins and Alzheimer’s, Paraquat Parkinson’s risk, mitochondrial transfusion therapy, fasting neuroprotection, ketosis brain optimization, natokinase soft plaque removal, sleep apnea cognitive decline, functional medicine Alzheimer’s, hippocampal volume preservation, nootropics cognitive resilience, learned helplessness medicine Thank you to our sponsors! EMR-Tek | Go to https://www.emr-tek.com/DAVE and use code DAVE for 40% off. fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. OneSkin | Get 15% off your first purchase at https://oneskin.co/ASPREY with code ASPREY. Resources: • Dale’s Website: https://www.apollohealthco.com/dr-bredesen/ • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:10 — Introduction 2:43 — Personal Story 7:52 — APOE4, Genetics, and Drug Development 11:37 — Pharma, Media, and Pushback 17:13 — Prevention, Stages, and Biomarkers 23:34 — Causes and Mechanisms 30:24 — Parkinson’s, Toxins, and Mitochondria 37:17 — Longevity, Biohacking, and Protocols 44:11 — AI, Data, and Future Treatments 54:11 — Case Studies and Success Stories 1:03:00 — Detox, Mold, and Environmental Triggers 1:12:00 — Neuroplasticity and Brain Regeneration 1:20:00 — Hormones, Supplements, and Personalized Hacks 1:29:00 — Cortisol, Addison’s, and AI Protocols 1:38:00 — Large-Scale Trials and Global Impact 1:45:00 — Final Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 22

Your hormones may be waging a hidden war that determines how long you live and how well you perform. This episode reveals how male and female biology diverge—and what those differences mean for your longevity, metabolism, and brain optimization. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Revisit this episode where Dave Asprey sits down with Teal Swan, a bestselling author and international speaker known for her work on human behavior, healing, and consciousness. Her insights bridge biology and psychology, uncovering how hormones, trauma, and environment shape both performance and resilience. Her ability to decode patterns of narcissism, victimhood, and trust through the lens of functional medicine and human performance makes her one of the most provocative voices in personal transformation. Together, they explore the science behind the hormonal divide between men and women—why birth control alters not just fertility but also male testosterone, why perception and neurodivergence impact neuroplasticity, and how early trauma imprints mitochondria and metabolism. You’ll learn how fasting, ketosis, cold therapy, sleep optimization, and smarter not harder strategies can shift your biology toward higher resilience and greater longevity. They also break down the biohacking tools and supplements that can help balance hormones, upgrade mitochondria, and fuel nootropics-level brain performance. From the hidden biological costs of hormonal birth control to how carnivore and targeted nutrition affect both male and female healthspan, this episode gives you a framework for hacking your biology at the deepest level. This is essential listening for anyone serious about biohacking, hacking human performance, brain optimization, functional medicine, or understanding how masculine and feminine biology directly influence lifespan and resilience. You’ll Learn: • How hormonal birth control impacts both women’s fertility and men’s testosterone • Why victim mentality rewires the brain and reduces neuroplasticity • How narcissism functions as a biological stress adaptation • The role of mitochondria, metabolism, and trauma in shaping healthspan • How fasting, ketosis, supplements, and cold therapy affect hormone balance • Why balancing male and female energetics may be a key to longevity Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: hormone war, male vs female longevity, hormonal birth control effects, testosterone collapse, estrogen disruption, masculine vs feminine biology, victim mindset neuroscience, narcissism as adaptation, betrayal and biology, neuroplasticity and trauma, perception and neurodivergence, fractal vision, birth trauma programming, mitochondria and stress, species-level hormone imbalance, industrial hormone disruption, male fertility decline, female hormone resilience, functional medicine hormones Resources: • Teals Website: https://tealswan.com/ • Teal’s YouTube: https://www.youtube.com/@TealSwanOfficial • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Cold Open 0:33 — Intro 2:49 — Defining Narcissism 5:48 — Gender Differences in Narcissism 7:47 — AI, Humanity, and the Future 10:25 — Extrasensory Perception & Childhood Experiences 14:04 — Birth Memories and Early Trauma 17:57 — Spiritual Abilities and Neurodivergence 22:48 — Functioning in the World with Unique Perceptions 23:45 — Trust, Support, and Creation 30:07 — Ego, Consciousness, and Spiritual Guides 33:46 — Dimensions and Multiverse Concepts 36:52 — Divine Masculine & Feminine 40:25 — Societal Imbalances and Gender Energies 46:20 — Hope for Humanity & Utopia 48:36 — Synchronization Workshops & Group Healing 51:30 — Science, Energy, and Invisible Communication 53:29 — Conclusion & Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 21

Walking speed predicts your risk of death better than cholesterol—and this episode reveals why. You’ll learn how to test your biological age at home in just 10 seconds, and how to use that information to upgrade your human performance, extend your longevity, and tailor your biohacking strategy for maximum results. Discover the overlooked role of pelvic floor strength, glute activation, and neuromuscular training in brain optimization, metabolism, and injury prevention. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey speaks with Dr. Vonda Wright, a double board-certified orthopedic surgeon, hormone optimization expert, and elite sports medicine pioneer who’s worked with Olympic athletes, military special forces, and high-performing women through every phase of life. With decades of experience in functional medicine, movement science, and hormone therapy, Dr. Wright shares the essential strategies to prevent frailty, rebuild strength, and thrive through perimenopause and beyond. You’ll learn: • How walking speed reveals aging and longevity better than traditional blood tests • The biomechanics behind muscle “shutdown” and how to turn muscles back on • The truth about C-sections, pelvic floor rehab, and functional motion assessments • Which supplements, nootropics, and hormone therapies restore metabolism and vitality • Why perimenopause is a turning point for brain, bone, and cardiovascular health • Testing tools and training methods to upgrade strength, prevent falls, and age powerfully Whether you want to feel stronger, think sharper, or stay youthful into your 90s, this is your roadmap for smarter not harder biohacking with real-world impact. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: 10-second walk test longevity, pelvic floor dysfunction and aging, glute activation for brain health, perimenopause hormone replacement therapy, VO2 max biohacking, estrogen for bone density, neuromuscular reactivation exercises, functional movement assessment AI, post-C-section core recovery, velocity training for longevity, strength vs muscle mass aging, menopause testosterone therapy, mitochondrial health for women, sleep optimization progesterone, cold therapy for muscle recovery, fascia training for anti-aging, diastasis recti long-term effects, smart exercise hacks for aging, hormone optimization for libido and brain, smarter not harder fitness protocols Thank you to our sponsors! Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 for 20% off your first order of PerfectAmino. Resources: • Vonda's Website: https://www.drvondawright.com/ • Vonda's Instagram: https://www.instagram.com/drvondawright/?hl=en • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:23 — Intro 2:55 — Muscle Atrophy and Reactivation 6:10 — Pelvic Floor Health and Rehab 8:47 — Joint Mobility and Movement 10:02 — Science of Muscle Function 18:23 — Perimenopause and Menolescence 27:58 — Four Essential Female Hormones 42:50 — VO2 Max and Longevity 49:24 — Velocity Training and Bone Health 62:30 — Turning Menopause into Power 65:58 — Closing Thoughts and Book Rec See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 19

Learn how to slow, and even reverse, your biological age with cutting-edge science on the molecule that controls your longevity. Host Dave Asprey sits down with Dr. Leonard Guarente, an MIT PhD and one of the most respected longevity researchers in the world, to reveal how NAD+, sirtuins, and DNA methylation clocks can help you hack aging, upgrade your mitochondria, and extend your healthspan. This episode gives you the real science, proven by over 250 studies, behind supplements, nutrition, and biohacking tools that actually work for brain optimization, metabolism, and human performance. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR You’ll learn why NAD+ is a master regulator of mitochondrial health, how DNA methylation clocks accurately measure biological age, and why boosting sirtuin activity improves resilience, neuroplasticity, and recovery. Dr. Guarente shares insider strategies from decades of functional medicine research, including nootropics, targeted supplements, fasting protocols, and diet adjustments from carnivore to Mediterranean that can shift your metabolism toward longevity. Dave and Dr. Guarente explore advanced biohacks like cold therapy, sleep optimization, and ketosis, plus how to balance these interventions with your genetics, lifestyle, and health goals. You’ll also hear about the surprising role of homocysteine in brain aging, how to use lab testing to guide your longevity plan, and why resilience is the ultimate measure of health. You’ll learn: • How emotional repression affects brain function, metabolism, and decision-making • Tools for nervous system regulation and emotional healing that drive high performance • Why most people fail without emotional intelligence and internal safety • How somatic awareness can optimize your energy, focus, and relationships • The science of fear, trauma release, and how to turn discomfort into growth • How to coach yourself out of stress, shame, and negative self-talk Whether you want to sharpen your brain, protect your heart, or upgrade your energy systems, this is a masterclass in smarter not harder biohacking for a longer, higher-performing life. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: NAD+ supplementation, Sirtuin activation, DNA methylation clocks, Biological age testing, Mitochondrial biogenesis, Epigenetic reprogramming, Pterostilbene benefits, Nicotinamide riboside (NR), Nicotinamide mononucleotide (NMN), Homocysteine reduction, Oxidative stress repair, Superoxide dismutase (SOD) activation, Functional medicine longevity, Healthspan optimization, Resveratrol bioavailability, Menopause mitochondrial support, Phenylbutyrate and protein folding, High-fat diet longevity studies, Neurodegenerative disease biohacking, INCHIANTI aging study Thank you to our sponsors! Screenfit | Get your at-home eye training program for 40% off using code DAVE https://www.screenfit.com/dave . Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Resources: • Elysium Website. Use code ‘UPGRADE25’ for 25% off the first month of a monthly subscription to any Elysium supplement: https://www.elysiumhealth.com/ • Dave Asprey’s Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Introduction to NAD & Sirtuins 0:59 — Intro 7:04 — Animal vs Human Aging Studies 10:07 — Discovery of Sirtuins 14:43 — NAD’s Role in Aging 15:34 — Resveratrol vs Pterostilbene 23:13 — Timing NAD Supplementation 36:34 — Diet & Lifestyle Factors 50:05 — Elysium’s Basis & Signal 1:00:03 — Future Clinical Trials 1:05:14 — Psychology of Aging & Wrap-Up See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 15

How do you activate your body’s natural repair system? How can you hack stem cells for faster recovery, brain optimization, and peak human performance? This episode reveals how to trigger stem cell release, direct them to the right tissues, and stack biohacking tools for maximum regeneration. You’ll learn science-backed strategies for boosting mitochondria, enhancing neuroplasticity, and extending longevity through targeted supplements, fasting, and functional medicine techniques. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey talks with Christian Drapeau, a leading stem cell scientist and founder of STEMREGEN. Christian’s decades of research have transformed our understanding of how stem cells repair the body, reverse damage, and amplify performance. He shares practical protocols to mobilize stem cells, improve microcirculation, and reduce inflammation so your body heals faster, functions better, and stays younger for longer. You’ll learn: • How stem cells rebuild muscle, brain, and organ tissue for optimal human performance • Why fasting rejuvenates bone marrow and increases stem cell effectiveness • The synergy between PEMF, vibration therapy, cold therapy, and stem cell activation • How microcirculation and inflammation control improve longevity and recovery • The best supplements and nutrients to support mitochondria and stem cell health • How to stack nootropics, ketosis, and brain optimization tools for lasting energy and focus This is essential listening for anyone serious about biohacking, longevity, human performance, mitochondria health, neuroplasticity, functional medicine, fasting protocols, supplements for recovery, brain optimization, smarter not harder healing, metabolism upgrades, cold therapy stacks, and next-level physical and cognitive resilience Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: STEMREGEN, biohacking, natural stem cell activation, human performance, longevity, mitochondria, neuroplasticity, fasting, bone marrow rejuvenation, functional medicine, supplements, brain optimization, metabolism, cold therapy, microcirculation, nootropics, ketosis, smarter not harder, recovery hacks Resources: • STEMREGEN Website: https://www.stemregen.co/dave for 20% off your first order. • Dave Asprey’s Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:00 — Why Some People Regenerate Better 1:52 — Testing Stem Cell Levels 2:58 — Natural Stem Cell Function 3:59 — Exercise & Stem Cell Response 5:13 — Tissue Turnover & Regeneration 7:03 — Bone Marrow Production 8:16 — Fasting & Bone Marrow 9:33 — Nutrition for Bone Marrow 11:14 — Traditional Meets Modern Science 12:58 — Training Bone Marrow 13:57 — Stem Cells as Repair System 34:20 — Stem Cells & Brain Injury 47:01 — Inside STEMREGEN Products 55:41 — Stress, Cortisol & Stem Cells 58:12 — Final Recommendations See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 14

How do you make tough decisions? How do you make them without fear or lying? This episode shows you how unresolved emotions disrupt decision-making, relationships, and functioning in peak brain performance. You’ll learn tips to rewire your nervous system for decision making, optimizing emotional intelligence, and regulating your body for high-level clarity, energy, and resilience. Discover biohacking techniques that use emotional release and somatic awareness to boost mitochondria, activate neuroplasticity, and achieve lasting personal transformation. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey talks with Joe Hudson, a world-renowned executive coach to unicorn founders and billion-dollar leaders. Joe works with a select group of top performers to unlock emotional clarity, leadership mastery, and deep personal change. His methods combine neuroscience, trauma healing, somatic therapy, and conscious coaching to help people perform at their highest level while becoming more authentic, fulfilled, and connected. You’ll learn: • How emotional repression affects brain function, metabolism, and decision-making • Tools for nervous system regulation and emotional healing that drive high performance • Why most people fail without emotional intelligence and internal safety • How somatic awareness can optimize your energy, focus, and relationships • The science of fear, trauma release, and how to turn discomfort into growth • How to coach yourself out of stress, shame, and negative self-talk This is essential listening for anyone serious about emotional intelligence, high-performance coaching, biohacking, somatic healing, trauma work, executive leadership, nervous system regulation, brain optimization, functional medicine, and building unstoppable inner resilience. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: Joe Hudson, Dave Asprey, emotional intelligence, nervous system regulation, somatic therapy, trauma healing, executive coaching, biohacking emotions, brain optimization, emotional mastery, making tough decisions, fear or failure, leadership development, negative self talk, childhood trauma, personal transformation, smarter not harder, stress relief tools, leadership listening Thank you to our sponsors! Puori | Head to http://puori.com/dave for 20% off, including subscriptions. Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. Active Skin Repair | Visit http://activeskinrepair.com/ to learn more and use code DAVE to get 20% off your order. Resources: • Sign up for a complimentary transformation guide from Joe: https://www.artofaccomplishment.com/ • Joe’s Art of Accomplishment Podcast: https://open.spotify.com/show/6MjoHFfLmNgo0Msais7IJ2 • Daily Insights on Twitter: https://tinyurl.com/4kazb783 • Dave Asprey’s Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Introduction 2:42 — Why We Struggle with Fasting 6:28 — Identity and Control Patterns 11:56 — The Nervous System and Decision-Making 23:33 — Letting Go vs. Forcing Change 28:09 — Rebuilding Every Organ with Anti-Aging Work 33:51 — How to Actually Feel Emotions (Without Getting Stuck) 39:18 — Upgrading the Subconscious 45:02 — Final Thoughts and Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 12

Toxins you cannot see are damaging your health, wrecking your metabolism, and quietly accelerating aging. This episode reveals how to detect the new poisons lurking in your home, how they sabotage mitochondria and brain optimization, and the biohacking fixes that restore longevity, energy, and human performance. You’ll learn actionable strategies you can implement right away, from functional medicine detox protocols to supplements that protect your nervous system and upgrade neuroplasticity. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Alan Bell, an environmental health attorney and author of POISONED . Alan’s landmark legal work and decades of investigative experience have exposed some of the most dangerous everyday chemicals in modern life. After surviving his own severe toxic exposure, he’s dedicated his career to helping others identify hidden threats, fight back against corporate negligence, and restore their health through targeted biohacking and functional medicine. You’ll learn: • The most common invisible poisons in homes and how they impact metabolism, mitochondria, and brain optimization • Biohacking techniques for detox, from supplements to fasting and cold therapy • How to protect longevity and human performance with targeted functional medicine strategies • Why your sleep optimization, ketosis, and nootropics stack may fail without toxin removal • The connection between environmental toxins, neuroplasticity, and emotional resilience • How to use smarter not harder thinking to upgrade your biology for the long term This is essential listening for anyone serious about biohacking, brain optimization, hormone hacking, nootropics, functional medicine, emotional resilience, and building a state of unstoppable energy. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: Alan Bell, Dave Asprey, environmental illness, toxic building syndrome, VOC exposure, multiple chemical sensitivity, U.S. chemical safety laws, environmental toxins, mast cell activation, mitochondrial health, ten most dangerous chemicals, biohacking detox, air filtration, flame retardant-free bedding, non-toxic cookware, chronic illness Thank you to our sponsors! Get 15% off your first purchase at https://oneskin.co/ASPREY with code ASPREY. BON CHARGE | Go to https://boncharge.com and use code DAVE for 15% off. Calroy | Head to https://calroy.com/dave for an exclusive discount. Resources: • Alan’s Website: https://alanbell.me/ • Dave Asprey’s Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:07 — Intro 3:45 — Life in a Bubble 5:40 — Building Syndrome Impact 7:04 — Legal Gaps 11:55 — Medical Blind Spots 13:04 — Chemicals + Mold 14:00 — Legal Barriers 17:15 — Environmental Disease Links 18:54 — Toxic Burden 20:53 — Media Awareness 21:55 — Hollywood Hazards 24:00 — MCS & Fibromyalgia 26:04 — Recovery Strategies 27:22 — Mast Cell Science 38:15 — Biohacking & AI 40:17 — Top 10 Chemicals 44:00 — Reduce Exposure 48:45 — Detox & Travel 50:20 — Legal + Media Power 52:33 — Chemical Industry Truth 56:19 — Policy & Advocacy 58:12 — Closing See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 8

Want to think faster, remember more, and rewire your brain for high performance? This special archived episode breaks down the real nootropic stack, neuroplasticity tools, and brain optimization protocols Jim Kwik uses daily, plus the biohacking routines that rebuilt his cognition after traumatic brain injury. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with world-renowned brain coach Jim Kwik, bestselling author of Limitless and advisor to billionaires, athletes, and Hollywood performers. After being labeled “the boy with the broken brain” as a child, Jim transformed his life through functional medicine, nootropics, cold therapy, neurorehab, and smart supplementation. He’s now the go-to expert on learning how to learn, with cutting-edge insights on memory, speed reading, focus, and cognitive recovery. Together, they reveal the most effective supplements for brain optimization, how to stack smart drugs with sleep optimization, the surprising downside of alpha GPC, and why things like ketosis, mitochondrial support, and even Danger Coffee are essential for modern cognition. You’ll also hear why your brain speed depends on your metabolism, the forgotten science of post-traumatic growth, and how to combine breathing, fasting, and cold therapy for massive neuroplasticity gains. Jim also shares his Brain Animal system, a new way to personalize your learning, decision-making, and communication based on your unique cognitive style. From performance to parenting, he shows how your “brain type” influences every part of life and how to hack it for focus, clarity, and flow. This episode is packed with high-impact strategies for biohacking your brain, improving human performance, upgrading memory, and building real resilience using smarter not harder protocols. You’ll Learn: • What Jim Kwik takes daily for brain speed, cognition, and mental stamina • The exact nootropics Dave Asprey uses (and the ones he avoids) • How sleep apnea nearly destroyed Jim’s performance and how he hacked it • The connection between mitochondria, memory, and metabolism • Why brain inflammation blocks focus and cognitive clarity • When to use cold therapy, hyperbaric oxygen, and stem cells for brain repair • How to know if your brain needs more acetylcholine and what happens if you overdo it • The best biohacking tools for focus, speed reading, learning, and flow state • Why your brain animal determines how you learn, lead, and connect Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keyword Index: Acetylcholine supplements, Alpha GPC vs CDP choline, Post-traumatic growth brain, Stem cells for brain repair, Hyperbaric oxygen therapy for TBI, Brain inflammation supplements, Learning disabilities recovery, Best supplements for neurogenesis, Brain fog biohacks, Brainwave training programs, Smart drug protocols, Cognitive stack routines, Mitochondrial support for cognition, Electrolytes for brain performance, Danger Coffee brain benefits, ADHD nootropics protocol, Sleep apnea and cognition, High dopamine supplements, Brain types and learning styles, Upgrade Labs review Thank you to our sponsors! Generation Lab | Go to http://generationlab.com/ , use code Dave20 for $20 off, and see what your body’s really doing behind the surface. GOT MOLD? | Go to http://gotmold.com/shop and use DAVE10 to save 10% and see what’s in your air. BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 to save 20% off your first order of PerfectAmino. Resources: • Jim's Website: https://www.jimkwik.com/ • Dave Asprey’s Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: • 0:00 — Introduction & Brain Health • 0:47 — Childhood Injury & Struggles • 2:53 — Adversity & Purpose • 6:31 — Nootropics & Optimization • 18:49 — Daily Biohacking Habits • 32:14 — Exercise & Brain Function • 34:21 — Learning & Cognition • 38:06 — Sleep & Resilience • 41:41 — Brain Types Explained • 52:16 — Parenting & Neuroplasticity • 57:19 — Limitless Update & Wrap-Up See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 7

What if the most powerful upgrades for brain energy, metabolism, and drive aren’t in mainstream medicine, but in rare peptides and misunderstood hormones? In this episode, you’ll discover the cutting-edge compounds, nootropics, and hormonal strategies that elite biohackers are using right now to optimize every part of their biology. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Jay Campbell and Hunter Williams , co-founders of BioLongevity Labs —a performance biotech company creating oral peptide-based products like BioMind and BioGutPro . Jay is a globally recognized expert in testosterone optimization, author of The TOT Bible , and a leading voice in hormone and peptide therapeutics. Hunter is a high-performance coach and podcast host focused on metabolism, mindset, and men’s health through functional medicine and advanced supplementation. In this high-energy, high-clarity conversation, the trio explore what’s working right now in advanced human performance, spanning hormone synergy, mitochondrial enhancement, libido compounds, nootropics, and muscle-preserving stacks. You’ll hear why Dave injects estradiol three times per week, how Jay and Hunter use oral bioregulators to improve gut-brain signaling, and what peptides are quietly reshaping the future of health. You’ll Learn: • Who should use estradiol—and how it can protect brain performance in men • The real role of testosterone and estradiol synergy in male health and longevity • How BioLongevity Labs is innovating with oral peptide delivery for cognitive and gut health • Why peptides like BPC‑157 , TB‑500 , PT‑141 , and SS‑31 are changing mitochondrial care • The truth about Melanotan‑1 , SLU , AOD‑9604 , GW‑501516 , and BAM‑15 • What makes BioMind and BioGutPro different from standard nootropic or probiotic stacks • Why libido and metabolic health are deeply connected • The dangers of unvetted peptide sources—and what to look for in quality and bioavailability This is essential listening for anyone serious about biohacking , hormone optimization , mitochondrial support , brain energy , nootropics , neuroplasticity , functional medicine , sleep optimization , metabolism , and smarter-not-harder living. Keyword Index: estradiol for men, Dave Asprey hormone therapy, Jay Campbell BioLongevity Labs, Hunter Williams performance coaching, BPC‑157 recovery peptide, TB‑500 tissue regeneration, PT‑141 libido peptide, SS‑31 mitochondria peptide, Melanotan‑1 for skin and mitochondria, SLU stack, AOD‑9604 fat loss peptide, GW‑501516 Cardarine, BAM‑15 mitochondrial uncoupler, oral peptide delivery, BioMind brain supplement, BioGutPro gut-brain axis, testosterone estradiol synergy, mitochondrial uncoupling, nootropic peptide stacks, performance biohacking supplements Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Thank you to our sponsors! Puori | Head to http://puori.com/dave for 20% off, including subscriptions. Leela Quantum Tech | Head to https://leelaq.com/DAVE for 10% off. ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. Resources: • BioLongevity Labs Website: https://biolongevitylabs.com/?ref=DAVE# • Dave Asprey’s Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 00:00 – Trailer 01:00 – Introduction & Early Days of Biohacking 02:03 – Peptides 101: Foundations and Frameworks 03:06 – Peptides for Healing, Cognition, and Longevity 07:56 – Bioregulators and Russian Innovations 11:07 – Side Effects and Safety of Peptides 22:27 – Oral Peptides and Product Innovations 27:41 – Body Composition, Hormones, and Fat Loss 32:02 – Testosterone, Estrogen, and Male Health Protocols 45:03 – Peptides for Performance, Fat Loss, and Longevity 1:26:32 – Loose Skin, Surgery, and Body Transformation 1:38:00 – Closing Thoughts & Product Recommendations See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 5

Ready to learn about the secret compounds, molecules, nootropics, and stacks that Big Pharma doesn’t want you to know about? This episode is packed with the exact dopamine-boosting compounds, stacks, and biohacking protocols that top performers are using to supercharge human performance, brain optimization, and long-term resilience. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Lucas Aoun, Australia’s leading biohacker and founder of Ergogenic Health. Known for his fearless, data-driven experimentation, Lucas specializes in nootropics, dopamine modulation, mitochondria, and functional medicine. He’s spent over a decade testing underground compounds, natural molecules, and hormone-based strategies to achieve elite-level brain and body performance. Together, they explore Russian-developed enhancers like Bromantane and ITPP , and reveal how these rare compounds impact dopamine regulation, neuroplasticity, and mental drive. You’ll learn how to upregulate tyrosine hydroxylase (your brain’s dopamine switch), build targeted stacks for motivation and confidence, and avoid the common supplements that quietly kill your ambition. They also dive into the connection between dopamine and testosterone, explaining how to rewire hormonal feedback loops to reclaim masculinity, energy, and purpose. From libido hacks and prolactin suppression to stacking dopamine with GABA and acetylcholine, this episode gives you a complete system for motivation mastery. Other key topics include the dangers of chronic ashwagandha use, sleep optimization for dopamine recovery, the truth about adaptogens and cold therapy, ketosis, fasting, DHT science, ciproheptadine microdosing, and why mitochondrial support is essential for long-term performance and metabolism. You’ll Learn: • The #1 Russian compound for explosive dopamine and drive • Why most “calming” supplements destroy your ambition • How dopamine and DHT shape masculinity and performance • Advanced biohacks for sleep, motivation, libido, and mood • The truth about serotonin dominance and how to escape it • Which functional medicine tools enhance brain energy and metabolism • How to build your own dopamine protocol using proven nootropics • Why mitochondrial health is the hidden key to motivation and mood This is essential listening for anyone serious about biohacking, brain optimization, hormone hacking, nootropics, functional medicine, emotional resilience, and building a state of unstoppable energy. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Thank you to our sponsors! OneSkin | Get 15% off your first purchase at https://oneskin.co/ASPREY with code ASPREY. Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. LMNT | Free LMNT Sample Pack with any drink mix purchase by going to https://drinklmnt.com/DAVE . Resources: • Lucas’s Website: https://www.boostyourbiology.com/ • Lucas’s YouTube: https://www.youtube.com/c/boostyourbiology • Dave Asprey’s Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Tags: dopamine boosters , russian nootropics , bromantane benefits , biohacking dopamine , boost motivation naturally , dopamine stack , lucas aoun podcast , dave asprey dopamine , nootropics for energy , secret russian compounds , brain optimization , biohacking supplements , increase dopamine levels , functional medicine hacks , hormone optimization , dopamine and testosterone , neuroplasticity hacks , superhuman energy , underground nootropics , dopamine protocols See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 1

Getting 50 grams of protein per meal may be the single most underrated biohacking protein strategy for muscle growth, metabolism, and longevity . In this episode, you’ll discover why animal protein vs vegan is not a fair match biologically, how hitting the leucine threshold activates mTOR for longevity , and why muscle is the most overlooked organ of aging. This is must-listen content for anyone optimizing human performance , hacking metabolism , or reversing muscle loss with food. Host Dave Asprey is joined by Dr. Gabrielle Lyon , a pioneer in Muscle-Centric Medicine® , functional medicine expert, and top authority on clinical nutrition for longevity . Trained by protein researcher Dr. Donald Layman, she brings decades of expertise on how to use high-protein diets , amino acid science, and functional medicine to radically improve healthspan and brain optimization . Dr. Lyon works with everyone from special operators to aging patients, making her one of the most trusted voices in anti-aging diet strategies. Watch this channel on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR You’ll learn: • Why 50g of protein per meal matters more than total daily intake • How mTOR and longevity are misunderstood in mainstream nutrition • Why protein vs plant protein debates ignore hard biological data • How leucine thresholds determine muscle activation • Why fasting and protein cycling beats low-protein veganism • How ketosis and protein intake impact metabolic health • Why many on a vegan diet experience sleep issues , hormone crashes , and reduced resilience • How functional medicine podcasts like this one reveal the truth about aging and muscle loss • What happens clinically when patients switch to a high-protein diet • How to use supplements , nootropics , and protein hacks to enhance neuroplasticity , mitochondrial energy, and total body performance If you’ve ever asked “what’s the best protein for muscle growth ?” or “how does protein affect metabolism in aging?”, this episode gives you evidence-based answers from the front lines of clinical nutrition . This channel is a must-listen for anyone serious about hacking their biology, upgrading cognitive performance, and using unconventional tools to create lasting transformation. Whether you’re tracking HRV, optimizing for deep sleep, or working toward metabolic resilience, these conversations deliver insights you won’t hear anywhere else. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Thank you to our sponsors! 40 Years of Zen | Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Lumiram | Go to http://healthlighting.com/dave to save 10% on your order. Resources: • Gabrielle’s Website: https://drgabriellelyon.com/ • Gabrielle’s IG: https://www.instagram.com/drgabriellelyon/ • Dave Asprey’s Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: • 0:00 Trailer • 0:51 Protein Controversy • 2:38 Leucine • 6:00 mTOR, Methionine, and Protein Synthesis • 9:00 Vegan vs. Carnivore • 16:00 Optimizing Protein Intake & Aging • 22:00 Carbohydrates, Hormones, and Female Health • 28:00 Environmental Impact & Food Sourcing • 34:00 Debunking Plant-Based Documentaries • 40:00 Key Takeaways & Closing Keywords: protein vs plant protein, 50 grams of protein, biohacking protein, mTOR and longevity, animal protein vs vegan, leucine threshold, Gabrielle Lyon, muscle-centric medicine, best protein for muscle growth, anti-aging diet, muscle as organ of longevity, fasting and protein, ketosis and protein, vegan diet risks, optimizing metabolism, high-protein diet, functional medicine podcast, Dave Asprey protein, aging and muscle loss, clinical nutrition for longevity See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 31

This episode reveals how military-grade sound frequencies can rapidly shift your mental state, enhance neuroplasticity, and accelerate brain optimization. You’ll learn how to hack your nervous system using real-time biometric data, how frequency compositions are changing functional medicine, and why sound is emerging as one of the most powerful tools for human performance and longevity. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey is joined by Rev. Michael Beckwith , founder of the internationally renowned Agape International Spiritual Center and one of the most respected voices in spiritual transformation and human potential. With over four decades of teaching, Michael has impacted millions through his work in consciousness, meditation, and high-performance inner development. Joining him is Henry Penix , founder of SOAAK Technologies, a cutting-edge frequency healing platform trusted by clinicians, elite performers, and even the US Air Force. Together, they explore how sound can rewire brainwaves, reduce anxiety, support sleep optimization, and create measurable changes in metabolism, mood, and mindset. You’ll learn: • How the Air Force is using frequency tech to support mental recovery and cognitive performance • What makes SOAAK’s custom sound compositions biologically effective • How sound impacts mitochondria, mood, and brainwave coherence • The link between sound healing, neuroplasticity, and high-performance states • Why hydration, supplements, and biohacking stacks boost sound-based protocols • The surprising connection between prayer, frequency, and emotional regulation • How to integrate sound biohacks with fasting, ketosis, sleep tools, and nootropics • Why this tech pairs with cold therapy, Danger Coffee, and smarter not harder principles This channel is a must-listen for anyone serious about hacking their biology, upgrading cognitive performance, and using unconventional tools to create lasting transformation. Whether you’re tracking HRV, optimizing for deep sleep, or working toward metabolic resilience, these conversations deliver insights you won’t hear anywhere else. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Thank you to our sponsors! Leela Quantum Tech | Head to https://leelaq.com/DAVE for 10% off. Active Skin Repair | Visit http://activeskinrepair.com/ to learn more and use code DAVE to get 20% off your order. ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order Resources: • SOAAK Website: https://www.soaak.com/dave • Dave Asprey’s Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: • 0:00 — Trailer • 1:00 — Intro • 2:42 — Humor & Frequency • 5:20 — Soak App Origins • 8:15 — Biometrics & Sound Delivery • 10:40 — Inner Alignment & Brain Mapping • 13:46 — Beckwith’s Results • 19:44 — Sound & Biohacking • 23:32 — Mood & Sleep Shifts • 24:53 — Supplements & Water Synergy • 26:25 — Emotional Congruence • 29:49 — Frequency & Sexuality • 32:43 — Military & Medicine • 35:32 — Light, Sound & Quantum Effects • 40:34 — Analog vs. Digital Sound • 48:45 — Spiritual Experiences • 53:14 — Conclusion & CTA See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 29

You’ve been lied to about how long it takes to change a habit. This episode reveals a powerful, science-backed method to rewire your brain in just 63 seconds—without relying on willpower. You’ll discover how to use the 63-second window to interrupt destructive thought loops and how true habit change requires 63-day habit formation, not the popularized 21-day myth. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Dr. Caroline Leaf, a cognitive neuroscientist and best-selling author known for her groundbreaking work on the mind-brain connection. With over four decades of experience, Dr. Leaf has helped millions better understand the differences between the mind vs brain, how to harness intuition and neurobiology, and how to apply science-based tools for healing trauma with neuroscience. Her newest work, Help in a Hurry , builds on her bestselling book Cleaning Up Your Mental Mess , offering real-time tools to regain mental control during moments of emotional chaos. You’ll learn: • Why the 21-day habit myth persists and what the neuroscience actually shows • How to use the 63-second window to stop toxic thoughts from wiring into your brain • What happens during the 63-day habit formation cycle and how to stay on track • The difference between the subconscious vs unconscious mind • How to rewire your brain for better emotional regulation and decision-making • The power of forgiveness and how it relates to quantum entanglement • Caroline Leaf’s mental mess strategies to overcome triggers in real time • Why the free will neuroscience debate matters for your mental sovereignty • How to interpret intuitive “blips” through a neuroscience lens • Tools for using neuroplasticity to heal trauma, manage emotions, and boost clarity This episode is a must-listen for anyone interested in brain optimization, biohacking, human performance, mental resilience, and smarter-not-harder strategies for personal growth. Whether you’re focused on fasting, cold therapy, nootropics, sleep optimization, or upgrading your mitochondria, these mental frameworks will amplify your results. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Thank you to our sponsors! Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order IGNITON | Go to https://www.igniton.com/DAVE and use code DAVE to save 15%. Resources: • Order Caroline’s New Book ‘Help in a Hurry’ - https://a.co/d/6O9RaJB • Caroline's Website: https://drleaf.com/ • Dave Asprey’s Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: • 0:00 Trailer • 0:54 Intro • 1:12 63-Second Habit Rule • 5:14 21 vs 63 Days • 9:20 Habits vs Trauma • 14:19 Healing & Spiritual Insight • 17:43 Free Will & Mind-Brain Link • 19:11 Conscious vs Subconscious • 26:02 Intuition & Memory • 33:15 AI & Consciousness • 37:56 Death & Energy • 51:21 Forgiveness & Entanglement • 55:14 Self-Regulation Tools See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 25

What is Herbal Ecstasy —and why does it matter? This might be one of the most insane episodes we’ve ever recorded, and we had to bring it back because the story is too wild, too relevant, and too packed with real lessons in biohacking, brain optimization, and supplement hacking to miss. Host Dave Asprey sits down with Shaahin Cheyene, the renegade teenage entrepreneur who built a billion-dollar supplement empire before he could legally drink. As the creator of Herbal Ecstasy , Shaahin hacked natural compounds into high-performance nootropics that boosted energy, neuroplasticity, and metabolism—long before biohacking was a movement. He faced seven federal investigations, never spent a day in jail, and went on to pioneer the vaporizer industry and dominate Amazon with advanced supplement marketing. This episode explores how Shaahin reverse-engineered functional medicine principles, used ancient plant medicine to upgrade human performance, and scaled a controversial brand using raw hustle and hacking tactics. You’ll hear how Herbal Ecstasy worked, why it was banned, and what it teaches us about supplements, mitochondrial function, dopamine regulation, and the dark politics behind wellness innovation. You’ll learn: • Why Herbal Ecstasy became a billion-dollar underground supplement • How Shaahin used nootropics and adaptogens to hack energy, focus, and neuroplasticity • What his clash with the FDA reveals about supplement regulation and functional medicine • How dopamine, mitochondria, and metabolism drive human performance • The difference between hacking systems vs conforming to broken ones • How storytelling, podcasting, and controversial supplements build legacy brands Whether you’re optimizing your sleep, hacking your brain, experimenting with ketosis or fasting, or upgrading your stack with supplements that actually work—this channel delivers strategies, cautionary tales, and insight you won’t find anywhere else. lt is essential listening for anyone serious about biohacking, brain optimization, supplements, mitochondria, metabolism, functional medicine, nootropics, longevity, dopamine, cold therapy, sleep optimization, emotional regulation, neuroplasticity, fasting, podcasting, RFK-era health freedom, ketosis, entrepreneurship, and building influence smarter not harder—with or without Danger Coffee. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Thank you to our sponsors! Resources: • Shaahin’s Website: https://www.shaahincheyenne.com/ • Dave Asprey’s Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: • 0:00 — Trailer • 0:45 — Intro and guest setup • 4:39 — Escaping Iran and early hustle • 8:26 — Birth of Herbal Ecstasy • 14:21 — Explosive growth and legal heat • 25:06 — Lessons on money and business • 31:17 — Inventing the digital vaporizer • 40:03 — Hacking success on Amazon • 41:59 — Nootropics and the Limitless pill • 46:38 — Martial arts and mental resilience • 55:44 — Podcasting, media, and influence • 1:07:09 — Where to find Shaahin and closing thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 24

You’re leaving brainpower on the table, and this episode shows you how to reclaim it. Learn how to boost cognitive performance by 25% without relying on pills, stimulants, or gimmicks. Host Dave Asprey sits down with global finance expert and cross-cultural thinker Richard Conrad to explore how your cultural programming shapes your biology, metabolism, neuroplasticity, and even your ability to reach peak human performance. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Richard is the author of Culture Hacks and has spent over 30 years living and working across Japan, China, and the U.S. He’s a master of decoding hidden mental frameworks that influence perception, longevity, and decision-making. This is a must-listen if you care about brain optimization, functional medicine, and living smarter, not harder. Together, they break down why different cultures process truth, time, and identity so differently and how these filters influence your beliefs about supplements, fasting, cold therapy, sleep optimization, and more. You’ll also learn why Americans are biologically wired for linear logic, how agrarian versus warrior cultures shaped meditation and nervous system regulation, and how to train your mitochondria to perform like a samurai’s. You’ll Learn: • Why your culture shapes how your brain processes reality • How to shift from linear to systems thinking for better neuroplasticity • The connection between meditation styles, nervous system wiring, and mitochondria • How to apply ancient frameworks to modern biohacking and human performance • Why longevity without financial planning is a broken strategy • How to avoid cognitive bias by decoding relative versus absolute truth This channel is packed with biohacking wisdom, from nootropics and ketosis to Danger Coffee, financial resilience, and how your beliefs about aging could be accelerating it. Whether you’re focused on hacking your brain, upgrading your metabolism, or extending your longevity, this is one of the most unique mind-expanding channels around. It is essential listening for anyone passionate about biohacking longevity, functional aging, mitochondrial testing, and next-gen human optimization. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Thank you to our sponsors! Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. OneSkin | Get 15% off your first purchase at https://oneskin.co/ASPREY with code ASPREY. Generation Lab | Go to https://generationlab.com/ , use code DAVE20 for $20 off , and see what your body’s really doing behind the surface. Resources: • Order Richard’s Book “ Culture Hacks ”: https://a.co/d/9122Q25 • Dave Asprey’s Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: • 00:00 Trailer • 01:10 Intro • 03:15 Middle East Perception Gap • 06:53 China’s Strategy & Trade • 09:53 Japan vs China Mindsets • 14:28 Logic: East vs West • 18:23 Cultural Tools for Life • 24:23 Global Population Crash • 30:18 Shifting Economic Power • 55:33 Smart Finance Principles • 01:09:28 Real Estate & Policy See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 22

This may be the most cutting-edge life extension technology you’ll hear about for decades. You’ll discover how mitochondrial transfusion, rejuvenation, and repair could reverse biological aging, supercharge your metabolism, and radically extend healthspan—all by upgrading the cellular energy systems that power every function in your body. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with inventor and tech entrepreneur Tom Benson, founder of Mitrix. After launching three successful Silicon Valley companies, Benson shifted focus to one of the most promising frontiers in science: mitochondrial bioreactors designed to regrow your own autologous mitochondria. This isn’t theory—it’s a near-future anti-aging technology poised to transform functional medicine, personalized medicine, and the global conversation around aging reversal. They explore how mitochondrial DNA mismatches affect aging, why mitochondria act like cellular AI cores, and how dysfunction in these ancient organelles contributes to neurodegenerative disease, metabolic decline, and cognitive disorders. You’ll learn how restoring mitochondria could enhance everything from stem cell therapy and nootropics to ketosis, fasting, cold therapy, and even sleep optimization. You’ll Learn: • Why mitochondria may be the real control centers of human biology • How mitochondrial transfusion could revolutionize longevity and functional medicine • The connection between mitochondrial dysfunction and Parkinson’s, autism, and ALS • Why brain optimization and neuroplasticity depend on cellular energy • How stem cell-derived mitochondria compare to nootropics and NAD • What happens when mitochondrial DNA and nuclear DNA are mismatched • Why early aging might start with your egg cells’ mitochondrial computing • How mitochondrial health influences metabolism, ketosis, and fat storage • Why stress, toxins, and pharmaceuticals like statins wreck mitochondrial function • What it takes to scale mitochondrial bioreactors for widespread human use • How mitochondrial hacking could improve immune function, sleep, and resilience • Why the future of biohacking might begin with testing and upgrading your mitochondria This episode is essential listening for anyone passionate about biohacking longevity, functional aging, mitochondrial testing, and next-gen human optimization. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Thank you to our sponsors! -ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. -Active Skin Repair | Visit http://activeskinrepair.com/ to learn more and use code DAVE to get 20% off your order. Resources: • Mitrix Website: https://www.mitrix.bio/ • Dave Asprey’s Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: • 00:00 Trailer • 01:42 Intro • 04:33 Mitochondrial DNA & Performance • 08:49 Challenges in Mitochondrial Therapy • 13:31 Future Applications • 19:07 Mitochondria & Longevity • 20:19 Traditional Medicine • 28:50 Space Exploration • 29:35 Human Fragility • 30:19 Aging Revisited • 32:52 Experimental Research • 36:04 Ethics & Risks • 41:24 Mental Health Links • 46:28 Treatment Breakthroughs • 51:01 Personal Longevity Hacks • 54:30 Wrap-Up & Contact See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 18

What if one spray could upgrade your brain, protect your mitochondria, and outperform IV therapy and liposomal supplements? In this episode, you’ll discover the breakthrough science behind topical glutathione delivery that uses your skin’s water channels to raise intracellular glutathione levels in just 60 seconds. Learn how this powerful antioxidant works at the cellular level to reduce oxidative stress , support mitochondrial function , and drive real improvements in brain health , emotional resilience , and human performance . Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Nayan Patel , a world-leading pharmacist and formulator who pioneered this next-gen delivery method. With over two decades of clinical work in functional medicine , Nayan has helped reshape how we think about glutathione benefits , systemic detox, and performance optimization. His research shows that topical delivery bypasses traditional fat-based absorption, achieving higher brain uptake and faster results than IVs or capsules. You’ll learn: • Why glutathione for longevity is foundational to biohacking • How it protects against cellular inflammation and improves TBI recovery issues • Why pairing glutathione with NAD+ , vitamin C , or pharmaceutical nicotine creates a powerful synergy • How it preserves NAD+, supports sirtuins , and enhances ATP production • When to use glutathione as an immune booster for resilience and recovery This conversation also reveals the truth behind liposomal supplements , how your age affects glutathione absorption, and why this molecule is critical for anyone using nootropics , in ketosis , or pushing metabolic limits. This episode is essential listening for anyone into biohacking, cold therapy, functional medicine, or RFK-style medical freedom. You’ll walk away with practical tools to boost nitric oxide naturally, prevent dysfunction, and optimize your biology whether you’re on a carnivore diet or just looking for an edge. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Resources: • Auro Wellness Website: Use code ‘dave10’ at checkout https://aurowellness.com/ • Dave Asprey’s Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: • 00:00 Trailer • 00:20 Intro • 01:12 Water Channel Delivery Explained • 02:25 What Makes Glutathione Special • 05:04 Why IVs and Liposomes Fail • 06:29 Measuring Glutathione in the Brain • 10:42 Key Benefits and Use Cases • 20:49 Emotional Resilience Effects • 23:54 Sensitivity and Response • 24:55 Best Timing for Use • 25:53 Workout Performance Boost • 26:47 Brain Health and TBI Support • 28:22 Best Stack Combinations • 29:32 Nicotine + Glutathione Synergy • 33:18 Longevity, Sirtuins, and Genes • 40:36 Glutathione as Immune Booster • 43:15 Peptides and Next-Gen Hacks • 45:29 Dosing Tips and Wrap-Up See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 17

If you care about longevity, brain optimization, sexual performance, or metabolism, this molecule changes everything. Host Dave Asprey sits down with nitric oxide pioneer Dr. Nathan Bryan to reveal why this overlooked molecule controls your blood flow, mitochondrial energy, neuroplasticity, insulin response, and even your libido. You’ll learn how nitric oxide acts as a master switch for human performance and why the medical system has ignored it for decades. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Dr. Nathan Bryan is a world-renowned expert in nitric oxide biochemistry with over 20 years of clinical research, multiple patents, and collaborations with Nobel Prize-winning scientists. His groundbreaking work forms the foundation for modern functional medicine protocols targeting blood flow, metabolism, cognitive enhancement, and mitochondrial upgrades. You’ll learn: • How nitric oxide drives mitochondria, metabolism, and human performance • Why most nitric oxide supplements fail and how to spot real ones • The critical role nitric oxide plays in brain optimization, libido, and insulin signaling • How poor oral health, statins, and PPIs can kill nitric oxide production • What nitric oxide has to do with sleep optimization, aging, and disease prevention • How to stack nitric oxide with fasting, ketosis, nootropics, red light, and supplements • Why “Smarter Not Harder” starts with nitric oxide fueled upgrades This episode is essential listening for anyone into biohacking, cold therapy, functional medicine, or RFK-style medical freedom. You’ll walk away with practical tools to boost nitric oxide naturally, prevent dysfunction, and optimize your biology whether you’re on a carnivore diet or just looking for an edge. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Get Nitric Oxide products for 10% off with code ‘Dave’: https://bit.ly/Nitric-Oxide-Product SPONSORS: Leela Quantum Tech | Head to https://leelaq.com/DAVE for 10% off. Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Resources: • Nathan’s Website: https://www.n1o1.com • Nathan’s YouTube: https://www.youtube.com/channel/UCtftGy8e0r9DO8ActcyGi4w • Dave Asprey’s Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated : https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: • 00:00 Trailer • 01:03 Intro • 01:15 Why Medicine Ignores Nitric Oxide • 01:59 What Nitric Oxide Does in the Body • 04:46 How the Body Makes Nitric Oxide • 07:12 Diet’s Impact on NO Levels • 13:28 Why Most NO Supplements Fail • 19:32 Personalized Biohacking with NO • 22:33 How Medicine Misses the Mark • 30:40 Oral Health and Nitric Oxide • 31:30 Mouthwash Kills Your Microbiome • 32:28 The Problem with Fluoride • 33:25 Better Toothpaste for NO • 33:49 NO’s Role in Energy and Healing • 34:17 Blood Pressure and NO • 35:29 NO and Sexual Performance • 37:09 NO and COVID Recovery • 40:50 Brain Fog and NO Deficiency • 49:01 Carnivore, Sugar, and NO • 50:11 Why You Still Need NO Supplements • 54:19 Final Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 15

Supercharge your mitochondria, slash inflammation, and boost energy with one of the most overlooked hacks in human performance. This episode reveals how just 15 minutes of oxygen-based exercise can radically improve metabolism, brain optimization, and even reverse chronic conditions, without expensive gear or endless protocols. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Brad Pitzele, founder of One Thousand Roads and creator of the LEO System, an affordable and science-backed way to do Exercise With Oxygen Therapy (EWOT) at home. After nearly dying from autoimmune illness and failed functional medicine treatments, Brad used this oxygen-based biohacking tool to fully reboot his health. His story and system offer breakthrough potential for anyone facing fatigue, inflammation, or looking to upgrade energy, resilience, and longevity. You’ll learn: • How EWOT works differently from hyperbaric oxygen and why it’s faster • Why brain fog, poor sleep, and chronic inflammation all trace back to oxygen supply • How oxygen hacking activates neuroplasticity, detox pathways, and energy production • When to stack with ketosis, red light, nootropics, and mitochondrial supplements • How elite athletes and chronically ill patients both use this protocol • Why “Smarter Not Harder” starts with oxygen-fueled mitochondrial upgrades This is essential listening for anyone serious about biohacking, functional medicine, brain optimization, metabolism, fasting, supplements, and longevity. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Get a free Ebook on EWOT to learn more today: https://cdn.shopify.com/s/files/1/0097/3186/6683/files/The_Oxygen_Advantage_Protocol_-_EWOT.pdf?v=1752173567 SPONSORS: Puori | Head to http://puori.com/dave for 20% off, including subscriptions. BON CHARGE | Go to https://boncharge.com and use code DAVE for 15% off. Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • One Thousand Roads Website: https://www.onethousandroads.com/ • One Thousand Roads YouTube (more info on EWOT) : https://www.youtube.com/@OneThousandRoadsHQ • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Labs : https://upgradelabs.com • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 Trailer • 01:10 Introduction • 02:38 Discovering EWOT • 03:55 Autoimmune Breakdown • 06:54 Building One Thousand Roads • 15:00 EWOT Science & Benefits • 20:54 Protocols & Use Cases • 29:03 Real-World Results • 30:11 Brain Fog & Oxygen • 30:58 Athletic Performance • 31:41 Therapy Stacking • 34:44 Mitochondria & Aging • 37:08 Research & Studies • 40:00 Future of Oxygen Therapy • 43:02 Practical Tips & Access • 51:09 Final Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 10

Wrinkles are just the surface. This episode reveals what’s really happening beneath your skin and how to reverse it using stem cells, regenerative medicine, and the most advanced techniques in plastic surgery and aging. You’ll learn how to improve facial skin tightening, reduce inflammation, and trigger deep skin rejuvenation with stem cells, red light therapy, and targeted procedures that actually work. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey shares his personal journey through weight loss and skin excess, including why he had 28 inches of skin removed and how he rebuilt facial structure using stem cells and longevity protocols. He’s joined by Dr. Victor Urzola, a globally recognized expert in plastic surgery and aging, known for pioneering biohacking skin health techniques, cutting-edge facial reconstruction, and legalizing therapeutic stem cell use in Costa Rica. Together, they expose the hidden causes of wrinkles and aging, from mitochondrial slowdown to ligament laxity and collagen depletion. They also unpack the science behind breast implant health risks, silicone toxicity syndrome, and why thousands of women experience hormonal, neurological, and metabolic symptoms related to their implants. Dr. Urzola explains how explant surgery can improve hormone balance, sleep, HRV, metabolism, and even libido. You’ll also hear how cosmetic procedures interact with HPA axis function and how skin and brain health are more connected than you think. This episode is a must for anyone serious about biohacking, skin optimization, stem cells and longevity, and functional medicine. Dave also breaks down his recovery stack, including exosomes, red light therapy, collagen cycling, nootropics, and how cosmetic procedures can be used to enhance—not just appearance—but total human performance. You’ll learn: • The real root causes of wrinkles and sagging skin • How to use skin rejuvenation with stem cells for long-term results • Signs of silicone toxicity syndrome and what to do about it • Why cosmetic procedures impact hormone health and libido • The most effective strategies for facial skin tightening and recovery • How to approach breast implant health risks with functional medicine thinking Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. SPONSORS: Generation Lab | Go to https://www.generationlab.com/ use code Dave20 for $20 off. Qualia | Go to https://www.qualialife.com/dave15 to get an additional 15% off subscriptions. fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Dr. Urzola’s Website : https://drvictorurzola.com/en/ • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Labs : https://upgradelabs.com • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 Trailer • 01:39 Intro • 02:52 Breast Implants & Aesthetics • 03:40 Stem Cells in Cosmetic Procedures • 10:38 Skin Health & Anti-Aging Tips • 15:11 Red Light & Face Stimulation • 17:15 Platysma Muscle & Neck Aging • 21:01 Implant Risks & Reactions • 27:36 Vince & Longevity Science • 28:51 Implant Tolerance Explained • 29:52 Silicone Health Impact • 31:06 Inflammation & Genetics • 32:15 Explant Outcomes & Recovery • 40:14 Breastfeeding & Aesthetic Changes • 41:03 Lift vs. Implants • 45:39 Patient-First Medical Care • 53:32 Stem Cells & Medical Freedom • 56:21 Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 8

Superintelligence is coming faster than anyone predicted. In this episode, you’ll learn how to upgrade your biology, brain, and consciousness before AI and transhumanism reshape the future of health. Host Dave Asprey sits down with Soren Gordhamer , founder of Wisdom 2.0 , to explore what superintelligence in 2027 means for your mind, body, and soul. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Soren has spent decades at the intersection of mindfulness, technology , and human development. He advises leaders at OpenAI, Google, and top wellness companies, and he leads global conversations around AI and consciousness . His work bridges ancient wisdom with biohacking , modern neuroscience, and the urgent need to stay human in a machine-dominated world. This episode gives you a tactical roadmap to build resilience before the world tilts. You’ll gain practical tools for brain optimization , functional medicine , and biohacking strategies that sharpen cognitive health , reinforce emotional stability , and unlock peak human performance in a digital-first reality. From supplements and nootropics to neuroplasticity techniques , Dave and Soren show you how to protect your biology as AI accelerates beyond human speed. They break down how AI and human health intersect, explain why you need emotional strength to face the future, and offer guidance for raising kids in a world ruled by code. If you’re preparing for 2027 superintelligence , navigating AI-driven parenting , or staying ahead of transhumanist health tech , this episode equips you for the coming wave. You’ll Learn: • How AI is reshaping human connection, presence, and identity • Why emotional resilience and conscious awareness matter more than ever in an AI-driven world • How to raise connected, grounded children in a hyper-digital environment • What human flourishing looks like when technology outpaces biology • Why investing in presence, purpose, and inner development may be the ultimate upgrade • How leaders in wellness and tech are rethinking personal growth, governance, and ethics in 2027 • What it means to stay truly human—and fully alive—during the rise of superintelligence Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements , nutrition, hacking , emotional intelligence, and conscious living. Episodes drop every Tuesday and Thursday, where Dave asks the questions no one else dares and gives you real tools to become more resilient, aware, and high performing. SPONSORS: - LMNT | Free LMNT Sample Pack with any drink mix purchase by going to https://drinklmnt.com/DAVE . - ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Soren's New Book - The Essential : https://a.co/d/dALv7OS • Soren's Website : www.sorengordhamer.net • Soren's Instagram : https://www.instagram.com/wisdom2events/ • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Labs : https://upgradelabs.com • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 3

Creatine isn’t just for bodybuilders. It’s one of the most overlooked, science-backed nootropics for brain optimization, neuroplasticity, mitochondrial energy, and total human performance. This episode reveals why creatine is a non-negotiable supplement for anyone serious about biohacking, longevity, and cognitive upgrades. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey breaks down the myths and truths about creatine, uncovering how it enhances memory, supports your mitochondria, regulates mood, strengthens bones and heart function, and even aids fetal brain development during pregnancy. Drawing from decades of functional medicine, real-world biohacks, and new research featured in the Wall Street Journal , Dave explains how creatine works not only as a muscle booster but as a universal cellular fuel that supports brain benefits, memory improvement, and sleep optimization. You’ll learn how to harness creatine for everything from mental performance and mood regulation to faster recovery and better metabolism. Dave covers creatine dosage and timing, how to use creatine loading versus maintenance protocols, and how to enhance creatine absorption by mixing it with hot water or pairing it with glucose and protein to leverage insulin-sensitive pathways. He also shares next-level stacking strategies by combining creatine with caffeine (including Danger Coffee), beta-alanine, nitrates, and electrolytes to maximize both mental and physical results. Whether you’re using creatine for brain energy, sprint power, cold therapy performance, or cognitive resilience, this episode delivers practical tools you won’t hear anywhere else. If you’re following a carnivore diet, in ketosis, experimenting with fasting, or just want to feel sharper and more energized, creatine fits right in. Dave also explores cutting-edge options like GAA creatine, creatine HCL, and intranasal delivery systems, along with key nutrient pairings like TMG and folinic acid to support methylation and avoid side effects. Plus, he explains why vegetarians and vegans may need creatine the most. This is your complete guide to creatine brain benefits, mitochondrial support, memory enhancement, and smarter not harder living. You’ll Learn: • How creatine supports neuroplasticity, brain energy, and cognitive function • Why mitochondrial health is the key to memory, mood, and mental performance • The real science behind creatine dosage, absorption, and stacking strategies • How creatine fits into ketosis, fasting, and a carnivore lifestyle • Why vegans and vegetarians may suffer from creatine deficiency • How to combine creatine with caffeine, nitrates, and nootropics for peak performance • Ways to biohack your metabolism, muscle growth, and mental clarity • The link between creatine, sleep optimization, and reduced brain fog • How creatine protects against oxidative stress and supports longevity • What you need to know about GAA creatine, methylation support, and delivery mechanisms Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares and brings you real tools to become more resilient, aware, and high performing. SPONSORS: - Calroy | Head to https://calroy.com/dave for an exclusive discount. - BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 for 20% off your first order of PerfectAmino. Resources: • Danger Coffee : https://dangercoffee.com • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 Trailer • 01:14 Creatine for Overall Health and Longevity • 06:10 Addressing Common Myths About Creatine • 08:55 How to Use Creatine Effectively • 19:58 Special Use Cases and Recommendations • 24:58 Choosing the Right Creatine • 28:41 Conclusion and Recap See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 1

What if death isn’t inevitable but a solvable problem? This episode explores how biohacking is reshaping our understanding of mortality, legacy, and the limits of human performance. You’ll learn why some of today’s top thinkers are treating longevity as both a science and a spiritual movement, and how this shift affects your brain, your mitochondria, and your entire approach to life. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with philosopher and best-selling author Dr. Stephen Cave, Director of the Institute for Technology and Humanity at the University of Cambridge. With decades of expertise studying death, immortality, and ethics, Dr. Cave brings a rare depth of insight into how our desire to live longer intersects with neuroplasticity, supplements, and even nootropics. Together, they unpack the four universal immortality narratives, the dangers of mind uploading, and why AI might become humanity’s next god or destroyer. You’ll discover how legacy, ego, functional medicine, and even fasting and ketosis play into our fear of death. The conversation also dives into the deeper psychological and societal consequences of radical life extension, and what happens when biohacking crosses into belief. This episode is a must-listen for anyone serious about hacking longevity, brain optimization, metabolism, and building a future where living to 180 isn’t science fiction. You’ll also hear surprising thoughts on Danger Coffee, RFK, sleep optimization, and how to approach mortality using the Smarter Not Harder mindset. You’ll Learn: • Why all technology is a form of life extension • How ego and boredom threaten longevity more than disease • The real dangers of digital immortality and uploading consciousness • Why procrastination could be the enemy of eternal life • How to balance transhumanist tech with human values • The surprising connection between cold therapy, supplements, and meaning Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares and brings you real tools to become more resilient, aware, and high performing. SPONSORS: Puori | Head to http://puori.com/dave for 20% off, including subscriptions. Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Stephen's Website: https://www.ith.cam.ac.uk/staff/stephen-cave • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 Trailer • 01:09 Intro • 01:39 Life Extension Challenges • 02:05 Boredom and Mental Health • 04:28 Immortality vs. Enlightenment • 06:21 Death’s Role in Civilization • 09:06 Life Stages and Aging • 10:41 Global Immortality Narratives • 15:50 Personal Takes on Immortality • 20:46 Biohacking and Longevity • 28:43 Transhumanism Today • 31:00 Techno-Utopianism and Happiness • 32:20 Wealth and Fulfillment • 32:54 Purpose and Meaning • 34:00 Legacy and Death • 36:33 Near-Death and Mortality • 37:52 Time and Procrastination • 42:00 AI and Human Future • 45:56 Ethics of Life Extension • 50:35 Autonomy and Mortality • 52:35 Dangerous Ideas in Longevity • 55:53 Advice for the Young See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 27

You feel stiff, tired, or older than you should—and this episode shows you how to reverse it. Learn how to fix joint pain, restore youthful movement, and upgrade your longevity by hacking the hidden causes of early aging like mitochondrial dysfunction, leaky gut, and chronic inflammation. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Dr. Gregory Kelly, SVP of Product Development at Qualia Life and a leading authority on functional medicine, nootropics, and anti-aging science. Dr. Kelly is a naturopathic physician, author of Shape Shift , former editor of Alternative Medicine Review , and a university instructor who’s published over 30 peer-reviewed papers and contributed to the Textbook of Natural Medicine . His deep expertise spans cellular regeneration, sleep optimization, metabolism, and the chronobiology of performance. They reveal why most joint pain has nothing to do with age, why your cartilage and synovial fluid become insulin resistant, and how biohacking your gut can dramatically improve joint function and brain optimization. You’ll discover how neuroplasticity, metabolism, sleep, and mobility are all tied to your ability to stay pain-free and high performing. Dr. Kelly also breaks down the science behind unconventional joint-support compounds like tamarind seed extract, eggshell membrane, L-carnitine, and senolytics. You’ll Learn: • Why joint pain is often a metabolic and mitochondrial issue, not aging • How zombie cells and gut toxins silently destroy your cartilage • What to take instead of glucosamine to actually rebuild your joints • Why most joint supplements fail and what new research says to use instead • How to enhance mobility using functional medicine and cutting-edge ingredients • How movement, inflammation, and brain health are deeply connected • Tools for real recovery without burnout using the smarter not harder method This channel explores how ketosis, fasting, cold therapy, and smarter not harder strategies affect movement, inflammation, and longevity. Dave also shares how Danger Coffee and his own supplement routines helped him reverse years of joint damage—and how you can do the same without drugs or surgery. This is essential listening for anyone serious about biohacking, human performance, and outsmarting the aging process at any age. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares and brings you real tools to become more resilient, aware, and high performing. Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Qualia’s Website: www.qualialife.com/asprey15 • Qualia's Instagram: https://www.instagram.com/qualialife/?hl=en • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 Trailer • 01:07 Joint Pain vs. Aging • 04:46 Gut-Joint Connection • 06:33 Diet’s Impact on Joints • 10:14 Smarter Joint Supplements • 19:15 Senescent Cells and Pain • 22:47 Collagen Breakdown • 24:21 Tamarind and Turmeric Benefits • 26:34 Inflammation Fixes • 29:39 Mobility and Movement • 38:26 Sleep and Joint Recovery • 42:52 Can You Reverse Joint Damage? • 44:48 Final Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 26

93% of people are metabolically unhealthy, and it’s not because they’re lazy or eating too much fat. It’s because their bodies forgot how to burn fat at all. This episode gives you a complete roadmap to reboot your metabolism, escape the sugar-burning trap, and reignite your fat-burning engine for good. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Ben Azadi , functional health expert, best-selling author of Metabolic Freedom , and one of today’s most trusted voices in the ketogenic and fasting space. After reversing his own obesity through biohacking and functional medicine, Ben has helped millions unlock metabolic flexibility and master human performance through smarter-not-harder strategies. They explore how high insulin, not fat or salt, drives most chronic disease, and why your doctor probably isn’t testing for it. You’ll learn the truth about seed oils, fructose, and blood sugar spikes, and why most people using continuous glucose monitors are still missing the real metabolic threat. You’ll also discover how to: • Switch out of sugar-burning mode and back into fat-burning ketosis • Use fasting , cold therapy , and sleep optimization to repair mitochondrial damage • Fix hidden nutrient deficiencies with the right supplements , potassium , and electrolytes • Build real metabolic resilience with Danger Coffee , functional medicine , and nootropics • Avoid the trap of endless keto or carnivore and learn how to cycle your way to true metabolic freedom • Understand why low HRV , high insulin, and sleep debt crush longevity, energy, and brain optimization • Decode how neuroplasticity , emotional regulation, and resilience all connect to metabolism This is your science-backed guide to transforming your energy, losing stubborn fat, and becoming metabolically unstoppable. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. SPONSORS: - BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 for 20% off your first order of PerfectAmino. - IGNITON | Go to https://www.igniton.com/DAVE and use code DAVE to save 15%. Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Ben’s New Book - Metabolic Freedom: A 30-Day Guide to Restore Your Metabolism, Heal Hormones & Burn Fat: https://www.amazon.com/Metabolic-Freedom-Restore-Metabolism-Hormones/dp/1401994369 • Ben’s Instagram: https://www.instagram.com/thebenazadi/?hl=en • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 Trailer • 01:04 Intro • 02:42 Insulin Explained • 06:00 Salt vs. Potassium • 08:10 Uric Acid & Fructose • 12:56 Health Trolls • 18:14 Seed Oil Truth • 24:24 Cooking Oil Breakdown • 31:08 Carnivore & Flexibility • 34:57 Gut Test Insights • 36:09 Cholesterol Panel • 36:43 LMHR Explained • 37:39 Inflammation Markers • 40:25 Managing Autoimmunity • 42:07 Gut Bacteria & Fiber • 46:55 Fasting for Gut Health • 48:03 Saturated Fat & Gut • 49:34 Oxalates & Diet • 57:32 Metabolic Efficiency • 01:03:08 Hormesis & Stress • 01:08:21 Final Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 24

You’re working out, eating clean, and still not getting the results you want. This episode reveals the real reason your fitness isn’t translating to the summer body you’re chasing and what to do instead. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with performance-driven entrepreneur and former Army Ranger Nick Bare , founder of Bare Performance Nutrition and the Go One More movement. With over a decade of experience in human performance, endurance, and mindset training, Nick has built a cult-like following by pushing the limits of physical and mental resilience without burning out. In this episode, you’ll learn why consistency beats intensity , how to spot the traps of overtraining, and how to train smarter by understanding mitochondria function, recovery science , and sleep optimization . Dave and Nick go deep on longevity tactics , cold therapy , neurohacking rituals , and why emotional regulation is the missing link in high performance. They also break down elite strategies for entrepreneurial stress , parenting under pressure , and how to balance ambition with recovery using tools from biohacking , self-quantification , and functional medicine . You’ll get practical insights into how Upgrade Labs , Danger Coffee , and the principles behind Smarter Not Harder can dramatically boost your energy and focus. Whether you’re an endurance athlete, a sleep-deprived parent, or a business builder trying to avoid burnout, this conversation gives you the blueprint for sustainable energy, powerful willpower, and next-level fitness that actually works. You’ll Learn: • The true cost of overtraining and how to avoid it • How to create “sprints” in life without sacrificing long-term performance • Tactical upgrades for training, sleep, fasting, and emotional recovery • What most people get wrong about motivation and discipline • How to use nootropics , cold therapy , and fasting to accelerate growth • Why fear of mediocrity can be fuel if used correctly • How testosterone, cortisol, and dopamine affect parenting, performance, and purpose Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. SPONSORS: - Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order -Active Skin Repair | Visit http://activeskinrepair.com/ to learn more and use code DAVE to get 20% off your order. Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Nick’s Website – https://www.nickbare.com/ • Nick’s Instagram: https://www.instagram.com/nickbarefitness/?hl=en • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 Trailer • 00:55 Intro • 02:59 Longevity & health • 07:51 Endurance vs recovery • 20:23 Focus & boundaries • 23:16 Pain & recovery • 24:48 Dopamine & motivation • 25:48 Breath work & states • 28:24 Endurance as meditation • 30:44 Curiosity & fear • 32:22 Purposeful suffering • 33:33 Vision quests • 40:18 Nervous system switching • 45:59 Decision-making • 47:59 Final thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 19

Your everyday habits might be accelerating aging, and this episode reveals what to do instead. You’ll learn how specific plants trigger powerful longevity pathways and how to eliminate the hidden toxins disrupting your hormones, brain, mitochondria, and overall health. This is a masterclass in biohacking from two experts who’ve spent decades researching how to upgrade the human body. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey is joined by Darin Olien , environmental health expert, bestselling author of Fatal Conveniences , and co-host of the Netflix series Down to Earth with Zac Efron. Darin has traveled the globe uncovering forgotten plant compounds, investigated the most overlooked environmental toxins, and now works with leading scientists and governments to bring these breakthroughs into functional medicine and human performance. Together, they break down: • How rare plant compounds like osmotin support adiponectin and mitochondrial repair • Why PFAS, synthetic fragrances, and EMFs are sabotaging your biology • How environmental toxins contribute to hormone disruption and infertility • What makes tap water so dangerous and how to fix it with simple filtration • Why microplastics and heavy metals are harder to avoid than ever • The role of habit design, detox protocols, and indoor air quality in biohacking longevity • Why removing toxins first leads to better results in fasting, ketosis, nootropics, and cold therapy This episode delivers practical tools for building resilience, improving detox capacity, and navigating the modern world with awareness. You’ll also get insights into the systems that have failed to protect public health and how personal action can create collective change. If you’re interested in senolytics, sleep optimization, neurohacking, and smarter ways to upgrade your environment, you’ll find those topics explored in depth throughout this channel. Whether you’re detoxing from hidden toxins or optimizing with Danger Coffee, this conversation aligns with the core principles of Smarter Not Harder and the mission of Upgrade Labs. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. SPONSORS: -OneSkin | Get 15% off your first purchase at https://oneskin.co/ASPREY with code ASPREY. -Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. -Apollo Neuro | To get an Apollo wearable, go to https://apolloneuro.com/Dave and save 15%. Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Darin’s Website – https://superlife.com/ • Darin’s Instagram: https://www.instagram.com/darinolien/ • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 Trailer • 01:10 Intro • 02:14 Meet Darin Olien • 04:26 Wildfires and Pollution • 07:13 PFAS and Everyday Toxins • 12:37 Corporate and Regulatory Failure • 26:36 Synthetic Fragrances • 36:12 Water and Air Filtration • 36:53 Indoor Air Quality • 38:33 Building Healthy Habits • 40:05 Essential Oils and Hormones • 41:54 Tofu, Tempeh, and Estrogen • 46:34 Adiponectin and Biohacking • 47:04 Osmotin for Longevity • 49:48 Stem Cells and Repair • 53:57 Communicating Science • 01:04:12 Nutrition and the Microbiome • 01:06:14 Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 17

Your anti-aging skincare routine might be secretly aging you faster. In this episode, you’ll uncover how trending skincare products including vitamin C serums, harsh exfoliants, and blue light therapies can damage your skin’s mitochondria, accelerate senescence, and trigger systemic inflammation. You’ll learn how to reverse this damage, support cellular repair, and choose smarter formulations that work with your biology for long-term skin and brain health. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Amitay Eshel, a pioneer in biohacking skincare and founder of Young Goose. With expertise in regenerative aesthetics and advanced bioactive formulations, Amitay is leading the charge in applying longevity science, epigenetics, and senolytics to skincare. His work helps high performers integrate topical nootropics, mitochondrial support, and neurohacking principles directly into their daily routine through the skin. You’ll explore how skin aging connects to brain inflammation, how leaky skin barriers affect immune health, and why most anti-aging trends are outdated or biologically disruptive. The Human Upgrade unpacks how red-light therapy, ketosis, cold therapy, fasting, and self-quantification tools can be leveraged to enhance skin function from the inside out. This is a masterclass in smarter not harder skincare, rooted in cellular optimization and performance longevity. This episode is essential listening for anyone serious about biohacking, human performance, skincare longevity, mitochondria, Upgrade Labs-style recovery, and science-backed beauty routines. You’ll learn: • Which anti-aging skincare trends actually age you faster • How mitochondria and senescent cells influence visible aging and inflammation • What role neurohacking and the skin-brain connection play in longevity • How to repair the skin barrier and reduce oxidative stress naturally • The best red light, cold therapy, and fasting tools to reverse skin aging • How to use skin as a self-quantification tool for overall health • Why smarter skincare equals better cognitive and biological performance Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. SPONSORS: -OneSkin | Get 15% off your first purchase at https://oneskin.co/ASPREY with code ASPREY. -fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Young Goose Website – https://www.younggoose.com/ and use code “Dave10” at checkout to get a discount! • Young Goose Instagram: https://www.instagram.com/young_goose_skincare/?hl=en • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 – Trailer • 00:52 – Intro • 01:27 – Anti-Aging Mistakes • 05:20 – Skin Recovery Science • 07:44 – NAD & Mitochondria • 08:52 – Autophagy Compounds • 12:06 – Sleep & Topicals • 18:36 – Overtraining Effects • 21:07 – Vitamin C & Antioxidants • 28:48 – Breakthrough Formulations • 35:50 – Tallow vs. MCT • 36:11 – Sun & Longevity • 37:28 – Red Light Therapy • 40:12 – UV Light Benefits • 42:18 – Advanced Skincare Tech • 48:48 – NAD Topicals • 01:00:05 – Building Your Routine • 01:07:39 – Final Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 13

Most supplements don’t work, and this episode reveals why. You’ll learn how to stop wasting money on “expensive pee,” how to spot marketing lies on labels, and which ingredients actually move the needle for energy, focus, and longevity. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Jeff Boyd, founder of MTE and a leader in the new wave of performance supplements. With a background in data-driven wellness and a decade of experience optimizing human performance without caffeine or sugar, Jeff breaks down the science of nootropics, adaptogens, and smart nutrient stacking. His work focuses on self-quantification, nervous system regulation, and sustainable energy for founders, athletes, and high performers. Together, they explore why 85% of supplements are designed to fail, how to activate mitochondria for real results, and what it means to biohack your biology smarter, not harder. This isn’t just about supplements. It’s about reclaiming your energy, upgrading your brain, and aligning your stack with how your body actually works. You’ll also hear how fasting, sleep optimization, and even subtle neurohacking protocols support long-term resilience and better decision-making. You’ll Learn: • The real reason most supplements don’t absorb and how to fix it • How to build a caffeine-free stack that fuels energy, mood, and clarity • The latest in adaptogens, nootropics, and functional medicine • How to align your supplement timing with circadian biology and ketosis • Why “clean labels” often mean nothing • How emotional regulation and neurotransmitters shape performance • Tools for self-quantification and supplement personalization This is essential listening for anyone serious about biohacking, longevity, smarter supplementation, mitochondrial health, sleep optimization, emotional resilience, and conscious human performance. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks questions no one else dares and brings you real tools to become more resilient, aware, and high performing. Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • MTE website – www.getmte.com • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 Trailer • 01:13 Saffron Benefits • 02:26 Medicinal Herbs • 04:12 Supplement Formulation • 13:16 Theanine & GABA • 20:06 Adaptogens & Performance • 23:23 Stress & Muscle Growth • 24:03 Parenting & Energy • 27:47 Nervous System for Kids • 35:15 Sleep for Families • 36:41 Wrap-Up & Offers See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 12

Psychedelic therapy is on the verge of reshaping mental health, trauma healing, and human consciousness. This episode reveals what’s really happening behind the scenes at the FDA, inside pharmaceutical companies, and within the global movement to legalize MDMA-assisted therapy. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Rick Doblin , PhD, the legendary founder of MAPS and one of the most influential figures in psychedelic science. With nearly 40 years leading clinical research on MDMA, psilocybin, and trauma healing, Rick brings unmatched insight into how these compounds are transforming functional medicine, emotional resilience, and neuroplasticity. They break down the regulatory battle over MDMA therapy, the clash between pharmaceutical profit and public benefit, and the urgent need to combine pharmacology with therapy for real results. You’ll also learn how psychedelics impact neurohacking, epigenetics, and the default mode network—and why the next frontier of self-transformation may be couples therapy with MDMA. This episode offers critical knowledge for anyone serious about biohacking , trauma release, mental performance , and accessing deeper states of healing. This podcast channel dives into the intersections of psychedelics with fasting , ketosis , cold therapy , and self-quantification —and how altered states can unlock more energy, better relationships, and lasting change. You’ll Learn: • Why separating therapy from psychedelics is the most dangerous path forward • How MAPS evolved into a public benefit pharma company—and what went wrong • The real story behind the FDA’s rejection of MDMA therapy in 2024 • How MDMA affects neuroplasticity , mitochondria , and trauma recovery • Why group therapy and couples therapy are the future of psychedelic healing • The dangers of overusing ketamine—and how it’s being exploited by profit-driven clinics • What the Psychedelic Science 2025 conference will reveal about the future of medicine, spirituality, and consciousness hacking • How psychedelics could reverse epigenetic trauma passed down through generations • The role of default mode network suppression in spiritual experiences and trauma resolution • Why the war on drugs was never about safety—and what a post-drug-war world might look like Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee , and the father of biohacking . With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity , and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance , neuroscience, supplements, nutrition, neurohacking , emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. SPONSORS: - Leela Quantum Tech | Head to https://leelaq.com/DAVE for 10% off - ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Psychedelic Science Conference 2025 Website – https://www.psychedelicscience.org/ • Rick’s Website: https://maps.org/ • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 Trailer • 02:00 Intro • 03:43 Rise of Psychedelic Pharma • 05:00 Therapy vs. Profit • 06:44 Neurofeedback + Psychedelics • 08:28 Origins of Drug Laws • 14:06 MDMA Safety + Usage • 16:32 Psychedelics in Therapy + Meditation • 25:18 Psychedelic Hierarchy for New Users • 26:51 Psychedelic Churches + Culture • 28:58 Ayahuasca: Spiritual Insights • 30:24 MDMA and Federal Policy • 31:09 Inside the FDA Decision • 32:52 Therapeutic Promise of Psychedelics • 34:43 Psychedelics + Spirituality • 37:37 Neuroscience of Psychedelics • 40:12 Epigenetics + Generational Trauma • 43:50 War on Drugs Revisited • 46:37 Future of Legalization • 49:55 MDMA for Couples • 51:29 Group Therapy with Psychedelics • 52:26 Psychedelic Science 2025 Preview See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 10

You’ve been told to eat clean, but what if your “healthy” foods are wrecking your gut, crushing your hormones, and aging you faster? This episode exposes the nutrient-depleted truth behind modern diets, soil erosion, and why regenerative farming might be the key to reversing chronic disease, boosting mitochondria , and rebuilding your biology from the ground up. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Dr. Josh Axe, a trusted pioneer in functional medicine , bestselling author, and co-founder of Ancient Nutrition. Dr. Axe bridges the gap between biblical farming, ancestral nutrition, and modern science to explain how your food and even your supplements may be harming your human performance , digestion, and brain health. With clinical insights, personal stories, and science-backed tools, he shares what to eat instead if you want real longevity , energy, and healing. They dig into the collapse of soil nutrients, how monocropping damages the microbiome, and why organic food standards may be outdated. You’ll learn how regenerative agriculture rebuilds the earth and your gut, and why biohacking starts with dirt, not pills. Plus, they explore the hormonal chaos caused by seed oils, plastics, blue light, sleep disruption , and even birth control, especially in relation to testosterone loss in men and women. This episode also touches on biblical nutrition, fasting cycles, natural nootropics , testosterone-supporting peptides , the dangers of synthetic vitamins , and the future of real-time self-quantification . From poop-powered farming to smarter sourcing, it’s a wild ride into how food, faith, and farming affect every part of your biology. This is essential listening for anyone serious about biohacking , neurohacking , longevity , Upgrade Labs , Danger Coffee , Smarter Not Harder , and understanding the real root of disease and dysfunction. You’ll Learn: • Why regenerative farming beats “organic” for health and the planet • How depleted soil is linked to hormone imbalances and chronic disease • What birth control is doing to testosterone, fertility, and mitochondrial health • Why your supplements may just be “expensive pee” • The truth about biblical farming and why dirt still matters • How to support testosterone naturally with diet, peptides , and habits • Why sleep optimization , mineral balance, and circadian alignment are key for healing Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. SPONSORS: - BON CHARGE | Go to https://boncharge.com and use code DAVE for 15% off. - Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Josh Axe’s Website – https://thehealthinstitute.com/ • Josh Axe’s Instagram: https://www.instagram.com/drjoshaxe/?hl=en • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 Trailer • 00:52 Intro • 01:01 From Medicine to Farming • 02:21 Regenerative Farming • 03:36 Fixing Modern Agriculture • 05:43 Biblical Farming Meets Modern Science • 08:23 The Truth About Organic Food • 12:41 What’s Causing the Testosterone Crash • 18:07 Hormonal Birth Control • 27:37 New Hormone Replacement • 29:58 The Future of Health Tracking • 32:00 What Is Biblical Farming? • 33:38 Biblical Principles of Nutrition • 33:55 Foods Most Mentioned in the Bible • 35:17 Pork, Parasites, and Dietary Laws • 37:29 Chinese Medicine’s View on Pork • 39:36 Did the Flood Shorten Human Lifespan? • 42:26 Biodynamic Farming and Spirituality • 54:27 Fatherhood and Words That Heal • 56:21 What Josh Feeds His Kids • 01:03:41 Mental Health, Faith, and Healing • 01:05:36 Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 5

Your brain is under constant assault from devices you use every day. This episode reveals the hidden effects of 5G on brain function, cognitive performance, and nervous system stress, along with the science-backed method that neutralizes the damage. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Philipp Samor von Holtzendorff-Fehling, founder of Quantum Upgrade and a former VP at T-Mobile, to explore groundbreaking EEG research that shows how EMF exposure disrupts brainwaves in real time. Philipp shares how new tools are changing the way we approach biohacking, human performance, and energy medicine, and why even hardcore skeptics are paying attention. They break down double-blind studies, ATP production, and real-world EMF mitigation techniques that support brain health, mitochondrial resilience, and recovery. You’ll hear why professional athletes, clinicians, and even animals are benefiting from non-invasive approaches once dismissed as fringe, and how to evaluate what actually works in your own biology. This conversation is essential for anyone focused on biohacking , self-quantification , neurohacking , longevity , functional medicine , Upgrade Labs protocols , and protecting the brain in a wireless world. Whether you’re optimizing your nervous system, improving sleep, or just trying to stay sharp in a high-EMF environment, this episode gives you a toolset to reclaim your state. You’ll learn: • What EEG brain scans reveal after just 30 minutes of 5G exposure • Why ATP production increases in certain energetic fields • How energy fields influence brainwaves, stress, and performance • The connection between EMFs, mitochondrial function, and resilience • Why placebo doesn’t explain these results and what that means for self-tracking • How to use energetic tools alongside Danger Coffee , cold therapy , fasting , and nootropics Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares and brings you real tools to become more resilient, aware, and high performing. SPONSORS: - Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. - Calroy | Head to https://calroy.com/dave for an exclusive discount. Resources: • Quantum Upgrade Website – Go to https://quantumupgrade.io/Dave for a free trial. • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Quantum Upgrade Instagram: https://www.instagram.com/quantumupgrade.io/?hl=en • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 Trailer • 00:54 Intro • 01:18 Resistance to Energy Work • 03:25 Inner Intuition • 04:22 Science vs Experience • 09:12 Quantum Effects on Body • 13:43 Biohacking for Pets • 15:43 EMFs & Quantum Upgrade • 23:39 Explaining Quantum Tech • 27:58 Understanding Frequencies • 28:53 Scientific Proof & Use • 31:07 Brain Support Tools • 32:28 Ethics & Consent • 34:09 EMF Defense & Biofield • 39:07 Meditation & Altered States • 46:59 Performance Optimization • 48:02 Science Catching Up • 50:39 Free Trial & How to Try See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 3

Most people think 10,000 steps a day is the gold standard for health, but it’s outdated, inefficient, and often damaging. In this episode, you’ll discover a smarter, faster way to walk for longevity, fat burning, and total body resilience. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Mark Sisson , bestselling author, primal health pioneer, and founder of Primal Kitchen. With over 40 years at the forefront of fitness and ancestral health, Mark has helped millions rethink everything they thought they knew about cardio, running, metabolism, and movement. He was one of the first to challenge the chronic cardio myth, helped popularize ketosis and fat-adapted performance, and now returns with a new message: walking right, not more, is one of the most powerful biohacks for human performance and aging. They dive into the Japanese walking interval method that outperforms 10,000 steps, and explore the critical link between foot health , barefoot shoes , and the brain-body connection. Mark also shares why he trains just 20 minutes a week, why too much saturated fat might backfire, and why performance should never come at the cost of your mitochondria. You’ll learn how to build muscle and endurance with less effort, how to reverse foot dysfunction with every step, and how to age with strength, intuition, and freedom. This episode hits hard on biohacking , functional movement , longevity , self-quantification , and the real science of walking smarter, not longer. It’s also packed with insights on ketosis , nootropics , sleep optimization , and why perfectionism ruins health gains. If you’re serious about Smarter Not Harder strategies, tuning into your body, and reclaiming your natural performance potential, don’t miss this one. You’ll learn: • Why zone 1 walking beats zone 2 training for longevity • How foot dysfunction leads to systemic breakdown • The hidden brain-glute-big toe connection no one talks about • Why Mark no longer runs or eats ribeyes • The minimum effective dose for strength, mobility, and fat burn • Why perfectionism in wellness is toxic and what to do instead Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. **Go to www.peluva.com and use code ‘DAVE’ for 15% off ** SPONSORS: - LMNT | Free LMNT Sample Pack with any drink mix purchase by going to https://drinklmnt.com/DAVE . -Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Mark’s Website – www.peluva.com • Mark's Instagram: https://www.instagram.com/wearpeluva/?hl=en • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 – Trailer • 00:43 – Intro • 01:13 – Mark’s entrepreneurial journey • 04:53 – The rise of health blogging • 05:40 – Why cardio might be hurting you • 17:53 – Foot health and performance • 20:54 – Barefoot and minimalist footwear • 33:30 – Launching PVA Shoes • 42:59 – Diet’s role in foot recovery • 43:38 – Why comfort matters in footwear • 44:12 – Personal footwear hacks • 45:03 – Building a footwear brand • 46:21 – Fashion vs function in foot health • 49:17 – Simple foot strengthening tools • 52:35 – What history reveals about shoes • 58:47 – Walking and brain optimization • 01:06:41 – Protein, aging, and nutrition • 01:19:50 – Longevity and biohacking wins See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 29

This episode dives into the brutal, mind-altering experience of spending 60 days alone in Antarctica, and how extreme suffering became a catalyst for spiritual awakening, peak performance, and deep inner peace. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with elite adventurer, Marine Corps veteran, and Fearvana founder Akshay Nanavati , who dragged a 420lb sled solo across Antarctica in a brutal test of endurance, fasting, and spiritual transformation. Akshay shares how he used suffering as a tool to transmute PTSD, expand consciousness, and awaken what he calls the “paradox of oneness”—where discomfort unlocks the deepest joy. Together, they explore how cold therapy, isolation, and extreme hardship reshape dopamine, mitochondria, neurochemistry, and the stories we tell ourselves. Akshay’s journey through darkness retreats, trauma healing, and polar expeditions opens a raw and unfiltered look at self-quantification, mental resilience, and human performance at the edge. This episode will challenge your assumptions about comfort, suffering, and what it means to live fully awake. Whether you’re optimizing for longevity, exploring consciousness, or breaking free from invisible scripts, this conversation blends science, spirituality, and hardcore biohacking with moments of unexpected humor and wisdom. You’ll Learn: • How intentional pain resets your dopamine response and boosts performance • Why Akshay chose fasting and cold exposure over nootropics and psychedelics • How darkness retreats and solitude sharpen consciousness and intuition • The neuroscience behind pain, trauma, and transformation • Why true freedom lies in facing discomfort—not avoiding it • How to find God in suffering and create meaning from chaos Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. SPONSORS: - Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. - IGNITON | Go to https://www.igniton.com/DAVE and use code DAVE to save 15%. Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Akshay’s Website – https://fearvana.com/ • Akshay’s Instagram: https://www.instagram.com/fearvana/ • 2025 Biohacking Conference : https://biohackingconference.com/2025 • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 – Trailer • 00:58 – Intro • 01:55 – Meeting His Wife Through Intuition • 06:28 – Pain, Dopamine & Neurohacking • 15:19 – The Paradox of Oneness • 21:20 – Darkness Retreats & Mysticism • 34:39 – Constructing Reality • 38:32 – Consciousness & Perception • 39:18 – Polar Travel: Mental & Physical Strain • 40:22 – Calculated Risk vs. Suffering • 43:40 – Trauma as Fuel • 56:26 – Solitude & Self-Reflection • 01:05:45 – Embracing Fear & Building Courage • 01:09:29 – Death, Meaning & Bliss • 01:12:53 – Final Reflections on Purpose See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 27

This episode reveals how one simple breath pattern can rewire your nervous system, regulate stress in seconds, and become your most powerful tool for human performance and longevity. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Aaron Alexander, a world-renowned human performance coach, manual therapist, and creator of The Align Method . Aaron has worked with elite athletes, high-level entrepreneurs, and celebrity performers to transform the way they move, breathe, and live in their bodies. He merges structural alignment, functional medicine, emotional awareness, and deep nervous system science to help people get unstuck, physically and emotionally. Together, they explore the science and strategy behind breathwork, vagal tone, posture, and fascia, revealing how the body stores trauma, how breath shifts brain states, and how physical misalignment can sabotage mental clarity, energy, and even mitochondrial function. They also dive into why mouth taping, tongue posture, nitric oxide, and movement patterns are foundational to sleep optimization, cold therapy adaptation, and long-term vitality. You’ll learn how to regulate your state in 10 seconds or less, how to shift from sympathetic overdrive to parasympathetic calm, and how to use tools like humming, OMing, and deep exhales to control your biology in real time. This is a tactical, science-rich, emotionally grounded guide to neurohacking from the inside out. If you care about biohacking, functional medicine, sleep optimization, or want to feel stronger, calmer, and more in control—this episode is essential. You’ll also hear how Aaron: • Uses breath patterns to hack the nervous system and improve strength, mood, and cognition • Teaches mouth taping and facial alignment for deeper sleep and recovery • Connects trauma, honesty, and physical tension through a somatic lens • Guides clients through cold therapy, touch, and movement to recalibrate resilience • Applies fascia science and polyvagal theory to elite performance and everyday health This is essential listening for anyone exploring Smarter Not Harder protocols, high-level biohacking, and the connection between movement, mitochondria, and mind control. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares and brings you real tools to become more resilient, aware, and high performing. SPONSORS: - Sunlighten | Go to https://www.sunlighten.com/dave/ and enter code DAVE at checkout to save up to $1,400. Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Aaron’s Website – www.alignpodcast.com • Aaron's Instagram: https://www.instagram.com/aaronalexander/ • 2025 Biohacking Conference : https://biohackingconference.com/2025 • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 Trailer • 01:39 Intro: Walking, lifestyle design, and longevity • 05:38 Breathwork to shift state and boost energy • 21:16 Honesty, alignment, and nervous system health • 29:35 Safety, regulation, and somatic awareness • 30:43 Touch as therapy and connection • 31:53 Pheromones and subconscious signaling • 35:00 Breath as a tool for emotional control • 39:33 Growth through relationships and repair • 43:03 Nature’s role in healing and performance • 47:25 Tongue posture, eye movement, and fascia • 56:32 Final thoughts on presence and physical truth See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 22

This episode reveals the ancient health protocols Western medicine forgot, and how they are now being used to heal stress, rewire the nervous system, and radically improve human performance. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Mona Sharma , a renowned Ayurvedic practitioner, celebrity wellness expert, and functional medicine advocate who grew up in a Canadian ashram. Mona combines ancient Vedic practices with cutting-edge science to help her clients, including Will Smith and other high-profile figures, achieve high performance, emotional resilience, and deep-rooted healing. She translates the 5,000-year-old system of Ayurveda into practical strategies anyone can use to optimize health in today’s chaotic world. Together, they explore how Ayurvedic biohacking techniques like breathwork, circadian alignment, detoxification, and herbal medicine are now being validated by data in neuroscience, mitochondrial biology, and functional medicine. They also dive into trauma, stress rewiring, nervous system resilience, and how to build your own modern “ashram” for healing and longevity. You’ll learn how to shift from hypervigilance into calm, how to optimize vagal tone, and how ancient practices like tongue scraping and ghee detox intersect with modern tools like cold therapy , nootropics , sleep optimization , and self-quantification . If you care about biohacking , neurohacking , longevity , or want to understand how emotional states shape mitochondrial function, this episode is packed with grounded insight and powerful takeaways. It offers a masterclass in approaching health through both spiritual and systems biology perspectives, while avoiding burnout and noise. You’ll also hear how Mona: • Reversed her own heart condition after failed surgeries and medication • Guides high-stress clients using Ayurvedic principles and modern lab testing • Connects vagal nerve stimulation, breathwork, and emotional detox for lasting nervous system regulation • Uses personalized nutrition, pulse reading, and lifestyle upgrades to treat the root cause • Brings ancient healing into modern wellness spaces like Upgrade Labs This is essential listening for anyone exploring Smarter Not Harder protocols, blending functional medicine with high-level biohacking , and finding sustainable ways to enhance vitality without relying on pharmaceuticals or performance fads. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee , and the father of biohacking . With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity , and optimize every system in the body and mind. Each episode features cutting-edge insights in health , performance , neuroscience , supplements , nutrition , hacking , emotional intelligence , and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares and brings you real tools to become more resilient, aware, and high performing. SPONSORS: -Calroy | Head to https://calroy.com/dave for an exclusive discount. -ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Mona’s Website – https://www.monasharma.com/ • Mona’s Instagram: https://www.instagram.com/monasharma/?hl=en • 2025 Biohacking Conference : https://biohackingconference.com/2025 • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 Trailer • 00:54 Intro • 01:44 Mona’s Personal Healing Journey • 03:42 What Ayurveda Really Is • 07:15 Breathwork and Daily Rituals • 09:41 Where Western Medicine Falls Short • 13:27 Ancient Tools That Still Work • 22:02 Nervous System as the Healing Key • 31:50 Rewiring Through Visualization • 32:59 Transformations with Celebrity Clients • 33:31 Stress in the Public Eye • 34:18 Finding Core Values and Alignment • 35:48 Home Detox, Real Impact • 37:52 Blending Body and Spirit • 48:52 Understanding Your Dosha • 54:02 Applying Ayurveda Today • 58:34 Final Thoughts and Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 20

You’re being programmed, and it’s more subtle and pervasive than you think. From invisible influence to psychological manipulation, this episode shows you how to recognize when your thoughts aren’t really yours. Host Dave Asprey uncovers the hidden science of mind control with Harvard historian Rebecca Lemov. She is a professor of the History of Science at Harvard University and one of the world’s leading experts on psychological manipulation, surveillance science, government experimentation, and Cold War brainwashing programs. Her groundbreaking research into MK Ultra, behavioral psychology, and reeducation campaigns reveals exactly how external forces hijack your thoughts, emotions, and decisions, without you knowing. They break down how mind control evolved from CIA-funded brain implants and LSD experiments into today’s algorithmic persuasion, trauma-based manipulation, and tech-driven influence. This episode gives you practical tools to defend your thoughts, upgrade your awareness, and reclaim your mental sovereignty. This is essential listening for anyone serious about biohacking, mindfulness, longevity, mental performance, self-awareness, hacking the nervous system, emotional control, and high-performance mindset training. You’ll Learn: • How the CIA used MK Ultra, psychedelics, hypnosis, and implants to test behavior control • What mind control looks like in modern media, social platforms, and persuasive technology • How unresolved trauma and emotional blind spots leave you vulnerable to manipulation • The connection between neurohacking, mindset, and mental autonomy • How to recognize when you are running someone else’s code • The best psychological tools to build resilience and conscious awareness • How to build a “mental firewall” with meditation, breathwork, and attention training Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. SPONSORS: -Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. -Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. -OneSkin | Get 15% off your first purchase at https://oneskin.co/ASPREY with code ASPREY. Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Rebecca’s New Book – The Instability of Truth: https://wwnorton.com/books/9781324075264 • Rebecca's Website: https://rebeccalemov.com/ • Rebecca’s Instagram: https://www.instagram.com/rebeccalemov/?hl=en • 2025 Biohacking Conference : https://biohackingconference.com/2025 • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 Trailer • 01:01 Intro • 01:49 Mind Control at Harvard • 02:54 Hypnosis and Mental Programming • 04:48 Morning Routines and Meditation • 06:02 AI Companions and Digital Influence • 11:17 MK Ultra and Government Experiments • 20:25 Archives and the War on Truth • 24:49 Marketing and Manipulation • 27:22 Chilling CIA Mind Control Stories • 33:59 Meditation and God Encounters • 34:40 Biohacking Origins • 35:15 Building Mental Resilience • 36:11 Compassion as Control • 37:54 Escaping Modern Programming • 39:57 Free Will vs. Influence • 46:03 Therapy and Suggestion • 49:25 SEER Training and Torture Simulation • 01:03:27 One-Pointed Focus • 01:06:46 Final Reflections See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 16

Your brain runs slow when it’s running on the wrong fuel. In this episode of The Human Upgrade , Dave Asprey sits down with Geoffrey Woo, Stanford-trained computer scientist and founder of Ketone-IQ, to reveal the high-performance brain fuel once reserved for Special Forces and elite athletes. Discover how ketones helped operators in combat zones sharpen focus, recover faster, and boost reaction speed by up to 30%. Learn why glucose falls short, how to hack your mitochondria for better cognition, and what it takes to unlock rapid-fire thinking on demand. This is brain energy for people who want to win, at life, work, and everything in between. Whether you’re fasting, flying, or facing real pressure, ketones flip the switch. You’ll Learn: • Why ketones beat glucose for focus, speed, and mental clarity • How Special Forces use ketones to recover brain function under stress • The truth about esters, salts, and the new wave of ketone diols • How ketones support faster thinking, emotional control, and clean energy • What makes Ketone-IQ different, and how Dave stacks it for peak performance • The best ways to combine ketones with fasting, workouts, and meditation • Why your metabolism controls your mood, reaction time, and resilience Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Ketone-IQ Website – https://ketone.com/pages/dave-asprey?utm_source=partners&utm_medium=referral&utm_campaign=DAVE • Geoffrey's Website: https://www.geoffreywoo.com/ • 2025 Biohacking Conference : https://biohackingconference.com/2025 • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 – Trailer • 02:00 – Intro • 02:12 – Ketosis & brain performance • 02:53 – Geoffrey’s background • 03:52 – Ketone supplement evolution • 04:41 – What makes Ketone-IQ different • 07:18 – Manufacturing breakthroughs • 13:53 – Entrepreneur mindset • 18:58 – Future of biohacking • 45:59 – Why classics still matter • 46:23 – Cultural decline • 47:04 – Decentralization • 48:25 – Info overload & mental clarity • 49:38 – Ketones & consciousness • 57:49 – Religion & belief systems • 01:03:32 – Key biohacking biomarkers • 01:12:47 – Brain data & future upgrades • 01:26:34 – Listener offer See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 15

Your cells are starving. Not for food—but for oxygen. In this episode of The Human Upgrade , Dave Asprey sits down with Dr. Jason Sonners , world-renowned hyperbaric expert and regenerative medicine pioneer, to reveal how controlled oxygen under pressure is becoming one of the most powerful tools in anti-aging and performance science. You’ll learn how hyperbaric oxygen therapy (HBOT) triggers stem cell activation, rewires your epigenome, boosts mitochondrial energy, and reverses biological aging—if you use it the right way. Jason shares breakthrough findings from his latest PhD research comparing low- and high-pressure chambers, with surprising results on inflammation, telomeres, cognitive performance, and recovery speed. This is next-gen longevity—measurable, stackable, and customizable. From sleep upgrades and HRV boosts to stacking HBOT with fasting, methylene blue, or red light, this episode dives into what it takes to oxygenate your biology at the deepest level. You’ll Learn: • How hyperbaric oxygen therapy (HBOT) triggers stem cell regeneration and cellular repair • Why mild-pressure chambers may be more powerful than you think • What HBOT does to inflammation, brain fog, and biological aging markers • How to stack HBOT with fasting, red light, and methylene blue for amplified results • What Dr. Sonners’ PhD research reveals about oxygen pressure and genetic expression • The truth about oxygen toxicity—and how to avoid the common mistakes • How elite performers use HBOT for brain optimization, recovery, and resilience ** Get 30% of yourr tickets to the Biohacking conference by going to https://biohackingconference.com/2025 and use code ‘OXYHEALTH’ ** Thank you to our sponsors! -Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Jason's Website – www.hbotusa.com • OxyHealth Website: https://www.oxyhealth.com/ • 2025 Biohacking Conference : https://biohackingconference.com/2025 • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 Trailer • 01:59 Intro • 03:14 New research on aging and oxygen • 05:39 Mild vs. hard-shell chambers • 13:05 HBOT for longevity and stem cells • 16:43 How to optimize your sessions • 22:35 Best therapies to stack with HBOT • 25:40 Oxygen delivery and safety • 26:43 Altitude and chamber effects • 30:01 Key benefits of hyperbaric therapy • 34:22 Supplement synergy and timing • 37:25 Pressure and oxygenation findings • 39:27 Medical vs. welding oxygen • 44:57 Safety myths and toxicity risks • 47:39 Future of biohacking with oxygen See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 13

Your brain has a gear you’ve never touched. Psychedelics can shift you into it. In this episode of The Human Upgrade, Dave Asprey uncovers how high-performance psychedelic mushrooms help you access flow states, rewire your brain, and enhance clarity, energy, and emotional resilience. This is next-level biohacking rooted in real science. You will learn how to use psychedelics with intention. When to microdose. When to go deep. How to stack them with nootropics for even stronger results. Dave breaks down the latest research on psilocybin, brain plasticity, trauma release, and how to turn ancient compounds into modern performance tools. What You Will Learn in This Episode: • How psychedelic shrooms unlock flow, focus, and creative power • Why psilocybin boosts neuroplasticity, mood, and emotional healing • Microdosing vs. full-dose: what works, when, and how • How to stack psychedelics with nootropics and other biohacks • The newest research on brain optimization and long-term benefits • How to use psychedelics safely, strategically, and for real results • Why shrooms may be the strongest mental upgrade in your toolkit Thank you to our sponsors! -Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. -fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Matt’s Website – https://mattzemon.com/ • Matt's Instagram - https://www.instagram.com/matt.zemon/ • 2025 Biohacking Conference : https://biohackingconference.com/2025 • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 – Trailer • 01:00 – Intro • 06:01 – Personal Psychedelic Journeys • 07:39 – Psychedelics and Self-Discovery • 11:59 – Safe Use and Smart Navigation • 29:09 – Psychedelics and Society • 36:40 – Building Trust in the Process • 37:14 – Facing Inner Fear • 37:38 – Choice and Healing • 37:51 – Diet and Conscious Decisions • 38:55 – Judgment and Relationships • 39:29 – Spirituality and Psychedelics • 40:07 – The Entheogenic Reformation • 41:29 – Past Lives and Expanded States • 43:44 – Where Science Meets Spirituality • 49:59 – Gratitude and Compassion in Healing • 01:01:47 – The Power of Apologies • 01:04:56 – Psychedelics in Therapy • 01:08:57 – Final Thoughts on Psychedelics and Culture See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 9

Low testosterone is sabotaging your health, motivation, and longevity. Diet alone will not fix it. In this episode of The Human Upgrade , Dave Asprey sits down with Shalin Shah, CEO of Marius Pharmaceuticals, to expose the truth about testosterone decline in both men and women. They break down why testosterone is crashing worldwide, why natural fixes almost always fail, and how the latest science finally makes testosterone therapy safer, simpler, and more effective than ever before. You will discover why testosterone is essential for dopamine, brain function, sleep, muscle, libido, and mitochondrial health. Fixing your levels can reverse fatigue, brain fog, poor motivation, and slow aging itself. Shalin reveals how new oral testosterone technology (Kyzatrex®) overcomes the dangers of old therapies and restores natural hormone rhythms without needles, creams, or dangerous side effects. What You Will Learn in This Episode: • Why testosterone matters for men and women at every age • The real causes of the global testosterone crash • Why diet, sleep, and exercise cannot fully fix low testosterone • How testosterone drives dopamine, motivation, and longevity • The breakthrough that makes oral testosterone safe and effective • How Kyzatrex® lowers SHBG and boosts free testosterone naturally • Why maintaining youthful testosterone levels protects brain, muscle, libido, and lifespan • How to safely use testosterone therapy without suppressing fertility or causing side effects ** Visit livethrive.co/asprey to get a discount on your first month's supply! ** Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Purchase Kyzatrex® – https://livethrive.co/?utm_campaign=11813552-Asprey • Shalin’s Instagram - https://www.instagram.com/themetabolicceo/ • 2025 Biohacking Conference : https://biohackingconference.com/2025 • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: 00:00 Trailer 00:52 Introduction 01:29 Global Decline in Testosterone Levels 02:27 Symptoms of Low Testosterone 03:48 Personal Journey with Testosterone Therapy 05:06 The Role of Testosterone in Overall Health 06:18 Testosterone Levels in Men and Women 08:48 Challenges and Innovations in Testosterone Delivery 16:25 The Importance of Circadian Rhythm in Testosterone Therapy 19:19 The Future of Testosterone Therapy 32:00 Investment and Development in Testosterone Therapy 34:57 Introduction to FDA and Hormone Replacement 35:31 FDA’s Impact on Women’s Health 36:10 Testosterone and Cardiovascular Risk 39:05 Testosterone and Depression 40:30 Testosterone Testing and Misconceptions 44:58 The Testosterone Project and Female Hormone Therapy 47:51 Testosterone’s Role in Longevity and Health 55:37 Cost and Accessibility of Testosterone Therapy 01:04:03 Conclusion and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 8

Your environment is rewiring your hormones, fertility, and long-term health without your consent. In this episode of The Human Upgrade , Dave Asprey sits down with Dr. Aly Cohen , board-certified rheumatologist, integrative medicine specialist, and environmental health educator. Together they expose how common toxins in plastics, pesticides, drinking water, personal care products, and food packaging are hijacking your biology. Dr. Cohen explains how daily chemical exposures contribute to autoimmune disease, thyroid dysfunction, hormone imbalance, infertility, obesity, cancer, and accelerated aging. You will learn how to identify hidden endocrine disruptors, spot surprising sources of microplastics and PFAS (“forever chemicals”), and apply science-backed detox strategies to protect your hormones, fertility, metabolism, and longevity. What You’ll Learn in This Episode: • How chemicals in household, cleaning, and beauty products disrupt hormones • The link between environmental toxins, autoimmune disease, thyroid issues, and infertility • Hidden sources of microplastics and PFAS chemicals and how to eliminate them • Affordable, practical steps to detox your home, water, and personal care routine • Dr. Cohen’s top biohacks to protect fertility, balance hormones, and build toxin resilience THANK YOU TO OUR SPONSORS! -BON CHARGE | Go to https://boncharge.com and use code DAVE for 15% off. -ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Aly’s Website – https://thesmarthuman.com/ • Aly's Website - https://alycohenmd.com/ • Aly’s New Book – Detoxify: https://alycohenmd.com/books • 2025 Biohacking Conference : https://biohackingconference.com/2025 • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: 00:00 Trailer 02:01 Introduction 02:15 Rheumatism and Rheumatology 03:36 Autoimmune Diseases and Toxins 04:17 Chemical Impact on Health 04:49 Personal Health Journey 06:15 Microplastics and Immune Disruption 08:21 Resilience and Lifestyle Changes 21:45 Nutritional Deficiencies 26:48 Lab Results and Assessments 34:40 Detoxification and Resilience 41:14 Personal Journey Continued 42:22 Clean Drinking Water 44:20 Travel Hacks for Water 46:15 Hotel Room Detox Tips 50:06 EPA Water Standards 53:06 Restaurant Toxins and Home Safety 55:36 Top Toxic Household Items 01:08:31 Synthetic Materials Impact 01:13:30 Final Thoughts and Book See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 6

What if you could reverse the age of your heart...without leaving home? In this episode of The Human Upgrade , Dave Asprey sits down with Dr. Anurag Singh, Chief Medical Officer of Timeline, to reveal groundbreaking science that targets cardiovascular aging at the cellular level. You’ll discover how mitochondrial decline drives heart failure, why postmenopausal women face skyrocketing cardiac risks, and how one powerful molecule, Urolithin A, can rejuvenate your heart’s energy systems. Dr. Singh shares clinical research showing how Urolithin A improves mitochondrial function, boosts endurance, and may even reverse biological aging markers in the heart. You’ll also learn how simple lifestyle biohacks, combined with cellular nutrition, can protect your cardiovascular health and extend your healthspan. What You’ll Learn in This Episode: • The link between mitochondrial decline and heart failure • Why women’s cardiac risk skyrockets after menopause • How Urolithin A stimulates mitophagy and energy renewal • New human clinical data on reversing cardiac aging markers • Biohacking strategies to fortify your cardiovascular health • How to optimize endurance, recovery, and heart resilience THANK YOU TO OUR SPONSORS! -STEMREGEN | Head to https://www.stemregen.co/dave for 20% off your first order. -Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Timeline Website – https://www.timeline.com/partners/dave-asprey • Timeline Instagram - https://www.instagram.com/timeline_longevity/ • 2025 Biohacking Conference : https://biohackingconference.com/2025 • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 — Trailer • 02:11 — Supplements that help • 03:05 — Long-term benefits • 04:38 — Stacking with lifestyle • 22:19 — Heart health connection • 29:39 — Mitochondria & brain function • 33:04 — Glymphatic system & Alzheimer’s • 33:53 — Bed height & brain health • 34:18 — Why mitochondria matter • 35:43 — Inflammation & dysfunction • 38:12 — Transplants & consciousness • 39:19 — Meditation’s effects • 40:33 — The ultimate biohacking stack • 43:06 — Creatine for sleep & focus • 50:00 — Fertility insights • 57:23 — Skin health • 01:00:28 — Final thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 1

What if a laser could help a child speak for the first time—or reverse an “incurable” brain condition? In this episode of The Human Upgrade , Dave Asprey talks with Dr. Brandon Crawford, a leading neurotherapist and founder of 528 Innovations, about the emerging science of laser therapy for the brain and body. You’ll learn how light—when precisely pulsed and targeted—can rewire brainwaves, heal trauma, and even influence states of consciousness. Dr. Crawford explains how specific laser frequencies are being used to modulate brain states, activate the vagus nerve, improve mood, restore gut-brain communication, and support recovery from conditions like autism and ALS. From EEG shifts to structured water and mitochondrial signaling, this conversation dives deep into biohacking’s most advanced light-based tech. What You’ll Learn in This Episode: • How laser therapy rewires brainwaves for mood, focus, and clarity • The exact brain regions linked to embodiment, intuition, and flow • Why pulsing patterns matter more than power in laser tech • How light influences trauma recovery and vagus nerve activation • The role of structured water and infrared light in cellular repair • How patients with ALS and autism responded to 528 protocols ** Get 30% off GA Virtual Tickets for the Biohacking Conference this May with code ‘528i30’ at checkout! ** THANK YOU TO OUR SPONSORS! -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. -LMNT | Free LMNT Sample Pack with any drink mix purchase by going to https://drinklmnt.com/DAVE . Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • 528 Innovations Website and used code ‘UPGRADE10’ at checkout – https://528innovations.com/dave • 528 Innovations Instagram - https://www.instagram.com/528innovations/ • 2025 Biohacking Conference : https://biohackingconference.com/2025 • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 – Trailer • 02:00 – Intro • 02:26 – New breakthroughs in laser therapy • 03:07 – Why laser tech needed reinvention • 04:21 – How laser light influences the brain • 08:03 – Holograms, light, and reality • 09:02 – Telepathy and autism connections • 12:03 – Rewiring the brain with light • 20:01 – Quantum signaling between cells • 22:33 – Biohacking and yogic practices • 22:54 – Testosterone and natural living • 23:37 – Boosting testosterone with lasers • 25:21 – Mitochondria and higher awareness • 27:35 – Laser benefits across the body • 30:29 – Advanced brain stimulation tech • 36:19 – ALS recovery and healing cases • 40:48 – Closing thoughts and next steps See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 29

What if mitochondria weren’t just energy engines — but conscious beings guiding your survival and evolution? In this episode, Dave Asprey sits down with Zach Bush, MD, to uncover a radical new science of cellular intelligence. Together, they reveal how your mitochondria, microbiome, and genetic memory do far more than support survival—they actively shape consciousness, drive healing, and accelerate human evolution. You’ll discover why chronic disease, fatigue, brain fog, and emotional trauma often trace back to lost cellular communication—and how restoring that network can unlock radical resilience, deeper energy, and true longevity. Through the lens of soil health, vibrational biology, light frequencies, and ancient microbial wisdom, Zach Bush shows why the future of biohacking demands reconnection to the deeper intelligence already alive inside you. What You’ll Learn in This Episode: • How mitochondria act as conscious messengers—not just energy factories—and why that changes everything about health and aging • Why rebuilding gut microbiome intelligence strengthens immune function, brain health, and emotional resilience • How disrupted cellular communication fuels chronic inflammation, autoimmune disease, and premature aging • How emotional trauma imprints onto genetic expression and triggers mitochondrial collapse • Why viruses and bacteria serve as evolutionary partners—not enemies—and how they upgrade your biology • How “cellular safety” activates healing, regeneration, and peak human performance • How carbon cycles, soil health, and light frequencies repair DNA and extend human lifespan • Simple daily practices that rebuild cellular coherence, boost energy, and reconnect you to your innate intelligence This conversation will rewire how you think about health, disease, and human potential—giving you the tools to upgrade your biology at the deepest level. **Check out Zach's exclusive offer for The Human Upgrade listeners at https://intelligenceofnature.com / and use code ‘DAVE10” for a discount!** SPONSORS - ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. - Apollo Neuro | To get an Apollo wearable, go to https://apolloneuro.com/Dave and save 15%. Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Zach’s Website – https://zachbushmd.com/ • Zach’s Instagram - https://www.instagram.com/zachbushmd/?hl=en • 2025 Biohacking Conference : https://biohackingconference.com/2025 • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 Trailer • 00:52 Intro: Microbiome and Human Connection • 03:07 Microbiome’s Role in Nutrition and Health • 05:48 Chemical Farming’s Impact on Soil and Health • 09:23 Mitochondria and Cellular Communication • 26:00 Viruses, Exosomes, and Evolution • 34:36 The Observer Effect and Reality • 40:08 Tech vs. Nature in Healing • 41:04 Light, Mitochondria, and Cellular Energy • 42:01 Choosing Tech or Natural Regeneration • 43:44 The Miracle of Life and Human Potential • 45:05 Healing Generational Trauma • 47:38 Shamanic States and Connection • 01:05:48 Sacred Geometry and Group Healing • 01:12:48 Rational vs. Mystical Perspectives • 01:14:52 Finding Common Ground • 01:15:10 Inside the Supplement Room • 01:15:47 Emerging Tech in Biohacking • 01:15:58 Non-Tech Health Upgrades • 01:16:11 Stem Cell Concerns and Cautions • 01:17:31 Nature Deficit and Health Impacts • 01:19:09 Curiosity and Personal Growth • 01:20:56 Generational Shifts and Gender • 01:24:20 Strengthening Relationships Through Differences • 01:28:31 Storytelling’s Power Over Data • 01:38:24 Longevity and Embracing Elderhood • 01:44:47 Final Thoughts and Future Visions See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 25

You’ve probably heard of HIIT—but have you heard of “REHIT?” This isn’t just another workout trend...it’s a new science-backed way to train with maximum efficiency and zero wasted time . If you’re still jogging, you’re wasting hours for minimal results. In this episode of The Human Upgrade , Dave Asprey sits down with Ulrich Dempfle , German-trained engineer and co-founder of CAROL Bike , to dismantle outdated cardio advice and introduce the 5-minute protocol that’s obliterating fitness myths. Forget the treadmill grind. REHIT (Reduced Exertion High-Intensity Training) exercising delivers: • 12% VO₂ max increase • 6x the fitness gains of daily jogging • 62% drop in diabetes risk • 5x more BDNF for brain power —all with just 8 minutes of effort per week. But was it? Ulrich unpacks the hard data, crushes the Zone 2 obsession, and shows how a brand-new way of exercising is giving explosive results—no matter your age or fitness level. What You’ll Learn in This Episode: • Why Zone 2 cardio is outdated advice for most people • The science of REHIT and how 2 sprints beat 2-hour workouts • The shocking data on VO₂ max, insulin sensitivity, and lifespan • How CAROL uses AI to personalize exercise for any age or ability • Why most people fail at fitness—and how to fix it • The real role of lactate, BDNF, and HRV in recovery and resilience • How perimenopausal women benefit more from REHIT than HIIT or jogging • Why adherence—not intensity—is the #1 predictor of results • What to do when you’re traveling or don’t have access to the tech Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • CAROL Bike Website and use code ‘DAVE’ for a discount – https://carolbike.com/ • CAROL Bike Instagram - https://www.instagram.com/thecarolbike/?hl=en • 2025 Biohacking Conference : https://biohackingconference.com/2025 • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 Introduction to REHIT Training • 00:24 Meet Ulrich Dempfle: The Mind Behind CAROL Bike • 00:51 The Science and Benefits of REHIT • 01:44 Comparing Traditional Cardio to REHIT • 02:32 Dave Asprey’s Personal Fitness Journey • 03:43 The Efficiency of REHIT Training • 05:03 Practical Applications and Accessibility of REHIT • 08:22 Addressing Common Concerns and Misconceptions • 11:25 The Future of Fitness: REHIT and Beyond • 18:29 Scientific Validation and Real-World Results • 31:53 Clinical Trials and Tech Integration • 32:06 Upgrade Labs and CAROL Bike • 33:00 Mitochondrial Effectiveness and Insulin Sensitivity • 36:05 Zone Two Training vs. High-Intensity Training • 42:02 REHIT for Perimenopausal Women • 48:18 AI and Personalized Exercise • 57:52 Lactate and Exercise Benefits • 01:01:48 Interval Walking Training • 01:04:01 Conclusion and Future Insights See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 24

Your bloodwork looks normal. Your doctor says you’re fine. But you still feel exhausted, inflamed, anxious—or worse. In this episode, Dave Asprey talks with Dr. Daniel Pompa , a leading voice in cellular detox and root-cause healing , to expose the hidden stressors hijacking your energy, hormones, and metabolism—even when your labs say you’re healthy. Dr. Pompa shares his personal health collapse and reveals how cellular dysfunction, neurotoxicity, and hormone resistance drive the chronic fatigue epidemic . If you’ve ever felt dismissed by “perfect” bloodwork, this conversation will rewire how you think about sickness—and show you how to reclaim real, lasting wellness. What You’ll Learn in This Episode: • Why your bloodwork can be “perfect” while your cells are on fire • The overlooked hormone resistances sabotaging your energy and metabolism • The 3-legged stool of chronic illness—and what actually drives disease • What “upstream detox” really means, and why most cleanses make you worse • Why toxins trigger genetic expression (and how to shut that down) • How to fix unexplainable fatigue, anxiety, and weight gain from the inside out • Why true healing starts with fixing the cell, not the symptom It’s time to stop chasing symptoms—and start upgrading from the root. **Check out Dr. Pompas EXCLUSIVE protocol built for The Human Upgrade listeners at davetestkit.com and use code ‘10OFF’ for a discount!** SPONSORS -Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. -Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Dr. Pompa’s Website – https://drpompa.com/ • Dr. Pompa’s Instagram - https://www.instagram.com/drpompa/?hl=en • 2025 Biohacking Conference : https://biohackingconference.com/2025 • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 Trailer • 00:55 Intro • 01:10 Healthy Is the New Sick • 02:27 Bloodwork & Hormone Resistance • 04:32 Dr. Pompa’s Health Collapse • 08:38 Toxins & Environmental Triggers • 15:01 Why Most Detox Fails • 29:16 The 5 Rs of Cellular Healing • 37:06 Olive Oil: Cure or Concern? • 38:11 Fat Balance for Energy • 42:13 Cholesterol & Saturated Fat • 46:26 Restoring Cellular Energy • 51:08 The Power of Diet Variation • 56:57 Plant Toxins Explained • 01:03:28 Emotional & Spiritual Detox • 01:13:55 Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 22

Most people run from stress. The world’s highest performers run toward it. Sébastien Page manages over $500 billion in global assets . He’s the CIO of one of the world’s largest investment firms, and he wrote The Psychology of Leadership while living under relentless pressure. His secret? He doesn’t avoid stress—he uses it as a tool for performance, clarity, and control. But here’s the twist: this isn’t just about boardrooms or billion-dollar trades. Whether you’re running a company, chasing a deadline, or just trying to stop procrastinating on your goals— this conversation will flip what you think you know about pressure, performance, and productivity . You’ll learn why trying to “relax your way to success” doesn’t work—and how to harness discomfort to create better decisions, higher output, and more resilience in every part of life. What You’ll Learn in This Episode: • The psychology of stress and why zero stress leads to burnout • How procrastination can boost creative performance • What astronauts, athletes, and leaders have in common • Why the key to better decisions is strategic patience , not speed • The stress-performance curve no one taught you in school • Why losing is the real path to mastery (and what Roger Federer can teach you) • The difference between being nice vs. being kind —and why it matters It's time to start turning stress into strategy . SPONSORS -fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. -BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 for 20% off your first order of PerfectAmino. Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Sébastien’s New Book – The Psychology of Leadership – https://www.psychologyofleadership.net/ • 2025 Biohacking Conference : https://biohackingconference.com/2025 • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 Intro • 02:00 Book Launch & Setup • 02:45 Buy or Sell? Market Insights • 03:20 Stress and Performance • 04:28 Sports Psychology Breakdown • 09:48 Federer & the Power of Losing • 26:42 Rethinking Feedback • 31:32 Stress as a Tool • 44:10 Listening as Leadership • 44:17 Traits of Great Leaders • 44:54 Psychology for Entrepreneurs • 45:37 Leading Beyond Work • 46:09 Sleep Tracking Anxiety • 47:39 Channeling Stress • 49:04 Extreme Pressure Moments • 50:42 The Corporate Athlete • 59:08 Vulnerability & Leadership • 01:05:23 Goal-Induced Blindness • 01:12:34 Finding Meaning at Work • 01:18:08 Leadership at Home • 01:20:27 Final Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 17

Your DNA, health data, and digital identity are encrypted, monetized, and weaponized against you. But what if there was a way to take it back… and hack the system? In this mind-expanding episode, Dave sits down with two elite hacker-founders— Michael Tiffany , CEO of Fulcra.ai , and Vishakh , founder of Monadic DNA —to explore a radical shift in the way we store, protect, and use our most personal data. Together, they break down the Web3 tech stack powering this revolution. Enter Nillion , a distributed, privacy-preserving compute network that allows you to share and analyze your encrypted data… without ever giving it away. From genomic privacy to AI sovereignty, this episode exposes the hidden architecture of control—and how to escape it. You’ll learn how cutting-edge blockchain and cryptography are rewriting the rules of ownership, consent, and even identity itself. What You’ll Learn in This Episode: • Why your DNA is already in government databases—and how long they keep it • How Nillion enables secure computation on private data • What it means to build a “cybernetic operating system” for your body • Why Fulcra.ai is building the orchestration layer of human optimization • How Monadic DNA helps you profit from your genetics—without giving them away • Why owning your data is the next frontier of biohacking • The surprising connection between decentralization, health freedom, and consciousness • How to join the movement toward true data sovereignty If you’ve ever felt like you’re giving away too much to big tech, big pharma, or just the internet itself—this conversation will change how you see your data… and your body. **Join the Fulca sleep study today! Visit https://fulcra.ai/sleep to sign up** **Get a 30% discount on Fulca with code “DAVE”! SPONSORS -IGNITON | Go to https://www.biohackingconference.com/ and get your tickets while there are still great discounts available. Go to https://www.igniton.com/DAVE and use code DAVE to save 15%. -Calroy | Head to https://calroy.com/dave for an exclusive discount. Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Fulcra Dynamics Website – https://www.fulcradynamics.com/ • MonadicDNA Website : https://monadicdna.com/ • 2025 Biohacking Conference : https://biohackingconference.com/2025 • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 – Trailer • 02:01 – Intro • 02:26 – Data Privacy & AI: The Big Shift • 03:21 – Meet Michael Tiffany • 04:41 – Cybernetic Operating Systems • 05:13 – Wearables & Personal Augmentation • 08:21 – Meet Vishakh: DNA Privacy Mission • 09:25 – Why Genetic Data Needs Protection • 11:30 – New Tech: Encryption & Privacy Tools • 16:13 – How Multi-Party Compute Works • 41:58 – Emergence: Behavior & Systems • 49:11 – Meditation & Mental Reprogramming • 50:20 – Distributed Computing & Biology • 56:15 – Environment Shapes Potential • 57:57 – Empowering Individuals at Scale • 01:00:31 – Biohacking Meets Inner Awareness • 01:04:01 – The Dark Side of DIY Mind Hacks • 01:06:09 – Future of Biohacking & Community • 01:12:28 – Integrating Genetic & Life Data • 01:20:39 – Why We Started Biohacking • 01:25:01 – Favorite Current Biohacks • 01:31:41 – Final Thoughts & Resources See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 15

If your brain feels foggy, your mood swings like a pendulum, or your cravings seem to control you—this episode will flip what you think you know about your body and your mind. Because what if your thoughts… aren’t really yours? In this mind-altering episode of The Human Upgrade , Dr. Steven Gundry reveals a startling new theory: your gut microbiome might be controlling your thoughts. From addiction and depression to obesity and inflammation, the microbes living in your gut—bacteria, fungi, viruses, even parasites—may be pulling the strings on your brain chemistry, mood, and behavior. Dave Asprey and Dr. Gundry dive deep into The Gut-Brain Paradox , exposing how the gut-brain axis operates more like a microbial command center than a digestive system. You’ll learn why probiotic pills rarely work, how the wrong microbes can drive compulsive behavior, and how toxic foods, glyphosate, and antibiotics have turned our guts into neurological war zones. Most shocking of all? Microbes may not just influence addiction—they may cause it. What You’ll Learn in This Episode: • How your gut microbiome can hijack your brain and influence your thoughts and behavior • Why certain microbes may actually cause addiction, obesity, and depression • How antibiotics, glyphosate, and processed foods are turning your gut into a desert • How to rebuild your gut ecosystem using postbiotics, fermented foods, and precision inputs • Why food cravings might be microbial mind control—and what to do about it • What the latest science reveals about the gut-brain axis, neurotransmitters, and neuroinflammation Sponsors: -Sunlighten | Go to https://www.sunlighten.com/dave/ and enter code DAVE at checkout to save up to $1,400. -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Dr. Gundry’s Instagram – https://www.instagram.com/drstevengundry/?hl=en • Dr. Gundry’s Website : https://drgundry.com/ • Dr. Gundry’s New Book The Gut-Brain Paradox: https://www.barnesandnoble.com/w/the-gut-brain-paradox-steven-r-gundry-md/1146019686?ean=9780062911803 • 2025 Biohacking Conference : https://biohackingconference.com/2025 • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 — Trailer • 02:01 — Intro • 03:55 — The Gut-Brain Connection • 04:45 — Microbiome Communication and Control • 08:19 — The Role of Fungi and Plants • 11:29 — Microbiome Diversity and Health • 19:05 — Addictive Microbiome and Behavior • 28:17 — Antibiotics and Gut Health • 30:49 — Listener Concerns and Gut Health • 31:02 — Whale Watching and Climate Change • 32:58 — Understanding SIBO and Bacterial Migration • 34:02 — The Role of Soluble Fiber and Fermented Foods • 36:12 — Complexity of Gut Microbiome • 36:49 — Restoring Ecosystems and Gut Health • 38:23 — Precision Microbiome Manipulation • 41:31 — Calcium Formation and Gut Bacteria • 43:56 — Oxalates vs. Lectins Debate • 46:04 — Whole Foods and Glyphosate Concerns • 51:47 — Dopamine Levels and Gut Health • 54:59 — Conclusion and Book Promotion See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 11

If your hair is thinning, shedding, or simply not what it used to be—and nothing seems to work—this episode is for you. Because what if the story you’ve been told about balding… is wrong? For decades, hair loss has felt like fate: genetic, inevitable, untouchable. But science is catching up to something deeper—something root-level. What if the real culprit behind age-related hair loss is cellular dysfunction? And what if we could change that? In this episode, Dave Asprey uncovers the cellular biology of hair thinning with longevity researcher Carolina Reis Oliveira. You’ll learn how senescent cells (aka zombie cells) hijack your scalp, disrupt follicle function, and silently accelerate hair loss—and how a breakthrough peptide might stop it cold. Carolina reveals brand-new clinical research on OS-01 , a molecule shown to increase hair density by 40% in just 6 months. But this isn’t a product pitch—it’s a paradigm shift. Together, they explore the hidden drivers of hair aging , from hormone shifts and stress cascades to microbiome imbalances and inflammation, plus the real science behind what can actually regrow hair. What You’ll Learn in This Episode: • How “zombie cells” (senescent cells) sabotage your hair from the inside out • The science behind the OS-01 peptide and how it reverses visible hair thinning • Why thinning hair isn’t just genetic—and what else is driving it • How stress, hormones, and aging collide to trigger follicle dysfunction • What your scalp microbiome has to do with regrowth and hair density • How to stack red light, peptides, and topicals for real, measurable results ***Visit oneskin.co/DAVE and use code DAVE for and additional 15% off.*** Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • OneSkin Instagram – https://www.instagram.com/oneskin.co/ • OneSkin Website : https://www.oneskin.co/ • 2025 Biohacking Conference : https://biohackingconference.com/2025 • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 — Trailer • 01:52 — Intro • 02:59 — Is Aging Optional for Your Scalp? • 04:03 — Understanding Scalp and Hair Aging • 05:06 — The Role of Senescent Cells in Hair Loss • 07:25 — Hormonal Influences on Hair Health • 16:10 — Peptide Solutions for Hair Thinning • 18:05 — Clinical Studies and Results • 20:29 — Future of Hair Loss Treatments • 30:16 — Nutritional and Lifestyle Factors • 36:40 — Addressing Senescent Cells and Hair Growth • 37:29 — Minoxidil: Oral vs. Topical Use • 39:32 — Personal Experience with Hair Products • 40:25 — Combining Therapies for Hair Growth • 46:06 — Nutritional Factors in Hair Health • 52:20 — Sun Exposure and Hair Health • 56:40 — Coffee and Hair Growth • 01:00:01 — Launching the New Hair Product See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 10

What if you could rewrite the code of your personality—on command? Not just cope with anxiety, overthinking, or social exhaustion… but delete the traits holding you back and install better ones? This episode challenges everything you’ve been told about identity. Dave dives deep into the science of personality change to reveal why your habits, moods, triggers, and even sense of self aren’t fixed—they’re fluid. And more importantly: they’re up for grabs. Joining him is award-winning journalist from The Atlantic, Olga Khazan, author of Me, But Better , who spent years hacking her own mind—transforming high neuroticism, social avoidance, and chronic self-criticism into calm, confidence, and connection. Her personal experiment in identity rewiring became a roadmap for anyone who wants to feel different… and live differently. You’ll uncover the hidden mechanisms behind neuroticism, reactivity, and emotional spirals—and how to override them with real-time upgrades. What You’ll Learn in This Episode: • Why your personality is a program —and how to recode it • What daily behaviors scientifically rewire anxiety, anger, and reactivity • The surprising link between identity, inflammation, and your gut • Why gratitude isn’t soft—it’s neurological jiu-jitsu • How to know if it’s your biology or your story running the show • Whether pills, psychedelics, or sleep do more to shift who you are • What to do when your inner critic won’t shut up • And how to stop being the person you never meant to become SPONSORS -LMNT | Free LMNT Sample Pack with any drink mix purchase by going to https://drinklmnt.com/DAVE . -Leela Quantum Tech | Head to https://leelaq.com/DAVE for 10% off. Resources: • Olga’s New Book – Me, But Better: https://www.amazon.com/Me-But-Better-Science-Personality/dp/1668012545 • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Olga's Instagram – https://www.instagram.com/olganator/?hl=en • Olga’s Website : https://olgakhazan.com/ • 2025 Biohacking Conference : https://biohackingconference.com/2025 • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 0:00 — Trailer • 1:52 — Intro • 2:16 — Personality Changes and Neuroticism • 5:38 — Postpartum Personality Shifts • 10:21 — Gratitude and Cultural Beliefs • 18:13 — Anger Management and Empathy • 32:58 — Personality Traits and Boundaries • 35:46 — The Importance of Strong Boundaries • 36:07 — Personality Change as Self-Improvement • 37:22 — The Role of Medication in Personality Change • 39:18 — Brain-Body Connection and Mental Health • 43:26 — Impact of Sleep and Nutrition on Personality • 44:23 — Nicotine and Other Substances • 45:41 — Therapy and Personality Change • 46:43 — Changing Personality Through Behavior • 1:01:25 — The Role of Relationships in Personality Development • 1:04:49 — Challenges and Methods in Personality Change • 1:08:38 — The Power of Improv in Personality Change • 1:10:17 — Conclusion and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 8

Your brain isn’t broken—it’s underpowered. Energy crashes, poor sleep, brain fog, and emotional reactivity don’t just happen. You’re running on low voltage, and your mind pays the price. In this episode, Dave sits down with Dr. Patrick Porter , founder of BrainTap, to reveal how to reprogram your brain using light, sound, and guided visualization —no substances, no side effects, no BS. Dr. Porter breaks down how to activate gamma brainwaves, repair trauma loops, access psychedelic-like states, and boost cognitive performance by 19% in just six weeks . You’ll learn why most brains burn out decades too soon—and how to charge yours back up. What You’ll Learn in This Episode: • How to flood your brain with energy and wake it up • The light and sound protocol that mimics psychedelics—safely • What gamma brainwaves unlock—and how to generate them on demand • Why your default mode network traps you in stress and distraction • The BrainTap protocol that improved cognition by 19% in 6 weeks • A real-life transformation story that rewrote one woman’s fate • The link between sleep, trauma, brain states, and performance • How to build a brain that performs like it’s decades younger This episode gives you a playbook to reclaim your focus, deepen your rest, and experience the full range of human consciousness—without touching a drug. Turn your brain on. Then turn it up. SPONSORS -STEMREGEN | Head to https://www.stemregen.co/dave for 20% off your first order. -BON CHARGE | Go to https://boncharge.com and use code DAVE for 15% off. Resources: • Biohacking Conference 2025 (May 28th-30th in Austin): https://biohackingconference.com/2025 (use code BRAINTAP to save 30% on General Admission and Virtual Tickets) • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • BrainTap Instagram : https://www.instagram.com/braintaptech/?hl=en • BrainTap Website: https://braintap.com/ • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 – Trailer • 00:35 – Intro • 00:50 – Meet Dr. Patrick K. Porter and BrainTap • 01:28 – The Science Behind Light and Sound Therapy • 03:38 – Quantum Biology and Frequency Medicine • 04:32 – Enhancing Cognition with Sound and Light • 06:19 – Biohacking Conference Highlights • 08:07 – Transformative Stories and BrainTap Benefits • 17:54 – The Role of Gamma Waves and Psychedelics • 26:55 – Conclusion and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 3

You think you’re helping your kid. You clear the path. You smooth the bumps. You make sure they never feel too sad, too bored, too uncomfortable. It feels like love. But what if it’s making them weak? In this episode, Dave Asprey sits down with bestselling author, TED speaker, and resilience expert Jennifer Cohen to reveal how today’s parenting norms are quietly producing the most anxious, dependent, and emotionally fragile generation in history— Gen Z . Whether you’re raising kids, managing young employees, or trying to understand the next generation—you’ll walk away from this episode with a new lens on resilience, responsibility, and real-world readiness. What You’ll Learn in This Episode: • Why Gen Z struggles with anxiety, confidence, and failure • How smartphones, safe spaces, and overparenting weaken resilience • The science behind boredom, chores, and grit-building discomfort • Why participation trophies are doing real psychological harm • The bold parenting shifts that build strong, adaptable adults • How to model strength—even when it’s unpopular • The simple framework to raise kids who can thrive, not just survive If you want to raise strong kids—or work with a generation that’s struggling—this episode is a must-listen. It’s not just about parenting. It’s about the future. And it starts with getting uncomfortable. SPONSORS -Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. -Qualia | Go to https://www.qualialife.com/dave15 to get an additional 15% off subscriptions. Resources: • A Day of Biohacking and Consciousness Even (4/12): https://daveasprey.com/biohacking-and-consciousness/ • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Jennifer’s Instagram : https://www.instagram.com/therealjencohen/ • Jennifer’s Podcast : https://www.youtube.com/channel/UCBuPgI8lXTmy5T0D_EDMnVg • Jennifer’s Website: https://www.jennifercohen.com/ • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 – Trailer • 01:59 – Intro • 03:38 – The Shift in Parenting Styles • 07:04 – The Role of Technology and Social Media • 10:59 – The Importance of Failure and Resilience • 13:38 – Practical Parenting Tips and Challenges • 24:06 – The Value of Chores and Responsibility • 26:24 – Balancing Luxury and Adversity in Parenting • 27:01 – Teaching Kids to Embrace Failure • 28:00 – The 10% Target: Encouraging Persistence • 29:35 – The Importance of Boredom and Creativity • 30:58 – Role Modeling Healthy Habits • 31:43 – Kids’ Reactions to Fast Food • 32:49 – Extreme Parenting: Biohacking and Kids • 36:30 – Rejection Therapy and Boldness • 42:42 – Praising Effort Over Intelligence • 45:32 – Challenges of Being Attractive and Intelligent • 49:31 – Instilling Self-Esteem in Children • 50:13 – Conclusion and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 1

For decades, gut health was reduced to yogurt commercials and vague promises from probiotics that barely worked. But what if we’ve been targeting the wrong bugs, using the wrong delivery, and ignoring the true source of chronic inflammation and accelerated aging? In this thought-provoking episode, Dave sits down with Hannah Kleinfeld, a leader in microbiome innovation, to expose why most probiotics fail—and how one company’s scientifically validated approach could redefine your gut, brain, immune system, and even your metabolism. You’ll learn how dysbiosis may be wrecking your brain without you knowing it, why your probiotic likely died in your stomach acid, and the secret to rebooting your microbiome after antibiotics, GLP-1 drugs, or years of toxic exposure. This isn’t just about digestion—your gut controls your cravings, energy, sleep, mood, and aging trajectory. So what’s the one upgrade that can actually reset your gut… for good? What You’ll Learn in This Episode: • Why your gut—not your brain—is making most of your decisions • How 93% of probiotics on the market fail before they reach your intestines • The “AB 10” protocol that rebuilds your gut after antibiotics or SIBO • What GLP-1 weight-loss drugs are doing to your microbiome (and how to stop it) • The shocking gut–brain–heart axis connection you’ve never heard of • Why inflammation, brain fog, and mood swings may start with leaky gut • Which probiotic strains are clinically proven to improve cognition and mood • What to do if you want to eat gluten again—or survive American wheat • How a fermented papaya concentrate could replace your acid reflux meds • Why optimizing your gut could extend your lifespan by 40% ***Get 20% off your next purchase by going to https://omnibioticlife.com/pages/dave-asprey/ or omnibioticlife.com/dave*** SPONSORS -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. -Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • OMNi-BiOTiC's Instagram – https://www.instagram.com/fatty15/ • OMNi-BiOTiC's Website : https://omnibioticlife.com/ • 2025 Biohacking Conference : https://biohackingconference.com/2025 • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 – Trailer • 03:15 – Intro • 05:05 – Probiotics, Prebiotics, and Postbiotics Explained • 08:21 – The Importance of Delivery Mechanisms • 17:36 – Addressing SIBO and Gut Health Protocols • 31:55 – The Impact of GLP-1 Drugs on Gut Health • 39:26 – The Role of Gut Bacteria in Hunger and Fasting • 40:01 – Painkillers and Gut Health: A Personal Experience • 40:51 – The Dangers of Proton Pump Inhibitors • 42:00 – The Importance of Stomach Acid • 44:55 – Probiotics for Chronic Conditions • 48:38 – The Impact of Glyphosate on Gut Health • 57:04 – Alcohol and Gut Bacteria • 01:02:01 – New Solutions for Acid Reflux • 01:07:57 – The Future of Gut Health and Longevity • 01:11:33 – Conclusion and Special Offer See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 27

For nearly a century, scientists believed we had discovered ALL of the essential fatty acids the human body needs. But what if they were wrong? Stephanie Venn-Watson, a veterinary epidemiologist and longevity researcher, joins Dave to reveal a groundbreaking discovery— a newly identified essential fatty acid, C15, that may hold the key to healthier aging and even longer lifespans. Originally uncovered in an unlikely place— U.S. Navy dolphins that were outliving their wild counterparts by decades —this forgotten fat is now shaking up the scientific community. So why hasn’t anyone told you about it?? Decades of misguided dietary advice stripped this crucial nutrient from our food system, leaving an entire generation unknowingly deficient. Even worse, pregnant women have been some of the MOST hurt from this cruel change to our modern diet. Now, cutting-edge research is proving that C15 plays a critical role in cellular stability, mitochondrial function, and total mental health. What You’ll Learn in This Episode: • The first new essential fatty acid discovered in nearly 100 years—and why it matters • How dolphins led to one of the BIGGEST breakthroughs in human nutrition • Why the removal of C15 from our diets is accelerating aging • The surprising connection between C15 and mental health • How this “missing” fat could outperform some of the biggest longevity drugs today! • What foods naturally contain C15—and should you supplement it? *** Get 15$ off Fatty15 at www.fatty15.com with code: DAVE *** SPONSORS Puori | Visit https://puori.com/dave and use code DAVE for 20% off. Calroy | Head to https://calroy.com/dave for an exclusive discount. Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Fatty15 I nstagram – https://www.instagram.com/fatty15/ • Fatty15 Website : www.fatty15.com • 2025 Biohacking Conference : https://biohackingconference.com/2025 • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: 00:00 – Intro 00:34 – Meet Dr. Stephanie Venn-Watson 00:46 – Discovering C15 in Navy Dolphins 01:58 – Challenges and Skepticism 04:21 – Scientific Validation and Research 06:59 – C15’s Impact on Human Health 27:43 – Big Data, AI, and Longevity Research 36:08 – C15 as a Longevity Nutrient 42:14 – The Navy’s Role in Fatty 15 43:03 – Epigenetic Aging and Lifespan 44:51 – Nutritional Guidelines and C15 Deficiency 50:41 – Mental Health and Endocannabinoids 51:33 – Dairy, Fats, and Nutrition History 56:38 – Fatty 15 in Skincare and Supplements 01:03:58 – Regulatory Changes in Nutrition 01:11:26 – Gender Differences in Fatty Acids See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 25

You think you’re optimizing your brain—but what if the real culprit behind your brain fog, anxiety, and burnout is the modern world itself? In this episode, Columbia University psychiatrist and nutritional neuroscience pioneer Dr. Drew Ramsey joins Dave Asprey to decode the biological chaos hijacking your mind—and how to fight back. From inflammation and gut dysbiosis to screen-induced disconnection and hidden trauma, this is the ultimate roadmap for healing the modern brain. You’ll explore the cutting-edge science of neuroplasticity, discover how movement and social connection trigger brain growth, and learn why food is still your most powerful antidepressant. Plus: dancing, psychedelics, kale debates, and why porn is quietly reshaping the male brain. What You’ll Discover in This Episode: • Why brain fog, anxiety, and mood swings might be signs your brain is inflamed • How movement—especially dancing—can literally help your brain grow stronger • What your gut has to do with your mental health (and why some “healthy” foods can backfire) • The truth about antidepressants, supplements, and why there’s no one-size-fits-all fix • Why porn, ultra-processed food, and doomscrolling are silently wrecking focus and drive • A new way to think about mental fitness—like a workout plan for your brain SPONSORS -BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 for 20% off your first order of PerfectAmino. -Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Resources: • A Day of Biohacking and Consciousness Event April 12th: https://daveasprey.com/biohacking-and-consciousness/ • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Drew’s Instagram : https://www.instagram.com/drewramseymd/?hl=en • Drew’s Linktree : https://shorturl.at/CIIR5 • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 – Trailer • 01:43 – Intro • 02:51 – The State of Mental Health Today • 04:00 – Nutritional Psychiatry and Personal Experiences • 05:21 – Environmental Factors and Brain Health • 05:55 – Chemical Balance and Psychiatry • 09:19 – Mental Fitness and Connection • 14:17 – Modern Brain Challenges • 16:26 – The Role of Movement and Dance • 22:44 – Sex, Relationships, and Mental Health • 34:02 – Microbiome and Mental Health • 36:50 – Transitioning to Urban Life and Mental Health • 37:29 – The Role of Nature in Mental Well-being • 38:14 – Personal Experiences with Gut Health • 39:45 – Trial and Error in Mental Health • 42:16 – Cognitive Resilience and High Performance • 45:37 – The Importance of Family Meals • 46:33 – Challenges of Rural and Urban Living • 47:53 – Brain Health: Beyond Neurons • 49:01 – Neuroplasticity and Mental Fitness • 52:50 – Biohacking Mental Health • 57:31 – The Role of Serotonin in Depression • 01:03:57 – Debating the Benefits of Kale • 01:12:03 – Final Thoughts on Mental Health and Resilience See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 20

You think, you feel, you are —but what if your consciousness isn’t just in your brain? What if reality itself is shaped by something beyond the physical? In this episode, Mark Gober—author, consciousness researcher, and former Silicon Valley banker—joins Dave Asprey to challenge everything you think you know about the mind, reality, and human potential. He explores groundbreaking research on near-death experiences, psychic phenomena, and why some scientists believe consciousness may exist beyond the body. Mark reveals how declassified CIA documents, quantum physics, and meditation practices point to a deeper, more interconnected world—one where perception creates reality. If you’ve ever questioned whether free will is an illusion, wondered about life after death, or wanted to tap into higher states of awareness, this episode will shift your perspective. What You’ll Discover in This Episode: • Is consciousness non-local? Why your brain might not be the source of your thoughts • Near-death experiences & life after death —the science and firsthand accounts • Psychic phenomena & remote viewing —what the CIA doesn’t want you to ignore • Float tanks, meditation & altered states —how to access expanded awareness • The AI consciousness debate —can machines ever become truly self-aware? • Protecting your energy —why spiritual safeguards matter when exploring altered states SPONSORS -Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. -fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Resources: • A Day of Biohacking and Consciousness Event April 12th: https://daveasprey.com/biohacking-and-consciousness/ • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Mark’s Instagram : https://www.instagram.com/markgober_author/ • Mark’s Websit e : https://www.markgober.com/ • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: 00:00 - Trailer 00:50 - Intro 03:11 - Meet Mark Gober 05:25 - From Banking to Awakening 10:16 - Float Tanks & Consciousness 12:35 - Psychic Phenomena 19:14 - Science & Skepticism 25:51 - Personal Experiences 40:51 - Spiritual Protection 42:58 - Parasitic Entities 44:59 - Psychedelics & Mindset 45:58 - Alien Abductions 47:04 - Navigating Psychedelics 51:58 - Intuition & Inner Knowing 58:41 - Telepathy & Remote Viewing 59:46 - Near-Death Experiences 01:04:54 - Consciousness Beyond the Brain 01:12:38 - Psychic Abilities & Ethics 01:24:11 - Consciousness & Reality 01:27:58 - Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 18

You hold the door open. You say yes when you mean no. You put others first—always. It feels like the right thing to do… but is it costing you more than you realize? In this episode, Scott Barry Kaufman, Ph.D.—Columbia professor, psychologist, and author of Rise Above—joins Dave Asprey to expose the psychology of victim vs. empowerment mindsets . He reveals how toxic altruism, external validation, and emotional fragility keep people stuck—and how you can reclaim your confidence, set boundaries, and create a life of true growth . Dr. Kaufman, one of the world’s most cited scientists , shares cutting-edge research on self-actualization, resilience, and the hidden mental loops that shape your success . If you’ve ever felt stuck in self-doubt, drained from over-giving, or afraid to take up space , this conversation will help you break free . What You’ll Discover in This Episode: • Victim vs. empowerment mindset —the key shift that changes everything • The psychological traps of toxic altruism —and why over-giving holds you back • How people-pleasing rewires your brain —and how to break the cycle • The science of self-actualization —how to unlock your full potential without guilt • Why modern culture and social media reward emotional fragility—and how to rise above it • The neuroscience behind confidence, resilience, and making better choices for YOUR growth If you’ve ever felt stuck, undervalued, or drained from always being “nice” , this episode will show you how to step into your power, rewrite your mental programming, and take control of your future. SPONSORS -Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Resources: • A Day of Biohacking and Consciousness Event: https://daveasprey.com/biohacking-and-consciousness/ • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Scott’s Instagram : https://www.instagram.com/scottbarrykaufman/?hl=en • Scott's New Book – Rise Above : https://scottbarrykaufman.com/books/rise-above/ • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 Trailer • 00:44 Intro • 02:02 Rise Above – Scott’s New Book • 03:13 Triggers and Mind Control • 05:12 Victimhood and Self-Actualization • 12:01 Curiosity Over Fear • 16:32 The Power of Discernment • 26:32 Emotional Resilience Today • 31:12 The Fragility of Younger Generations • 37:33 Social Pressures and Identity • 39:47 Social Media and Self-Determination • 40:35 Community and Belonging • 42:42 Activating Happiness and Growth • 44:43 Gratitude and Daily Practices • 51:48 Healthy Selfishness vs. Altruism • 58:56 Codependency and Vulnerable Narcissism • 01:04:57 The Dark Triad and Personality Types • 01:09:14 Final Thoughts and Book Recs See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 14

What do vibrations and the psychedelic experience have in common? MDMA therapy is revolutionizing mental health treatment, helping people overcome PTSD, anxiety, and emotional trauma with unprecedented success. But what if you could tap into those same powerful benefits—without taking a single drug? It turns out your brain responds to more than just chemistry. Vibration, frequency, and rhythm have been shaping human consciousness for millennia—from ancient chanting rituals to modern neuroscience breakthroughs. Could the right vibrations unlock the same neuroplasticity and healing pathways as psychedelics? In this episode, Dave Asprey sits down with Dr. Dave Rabin, a neuroscientist, psychiatrist, and psychedelic researcher, to explore how vibrations can rewire your brain, enhance neuroplasticity, and even mimic the effects of MDMA therapy. Dr. Rabin’s work led to the creation of Apollo Neuro, a wearable device that taps into your nervous system’s natural ability to regulate stress, boost focus, and accelerate recovery—without pharmaceuticals. What You’ll Discover in This Episode: • How specific vibrations trigger deep relaxation and neuroplasticity • Why MDMA therapy works—and how vibration-based tech can simulate it • The surprising science behind music, frequency, and altered states • How Apollo Neuro enhances sleep, focus, and emotional resilience • The overlooked role of heart rate variability in longevity and health • Why stress is the biggest obstacle to healing—and how to override it **Apollo Neuro | To get an Apollo wearable, go to https://apolloneuro.com/Dave and save 15%** Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Apollo Neuro Instagram : https://www.instagram.com/apolloneuro/?hl=en • Apollo Neuro Website : https://apolloneuro.com/Dave • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: 00:00 Trailer 00:40 Intro 01:18 Exploring Vibration in Biohacking 02:29 Introduction of Dr. Dave Rabin 02:53 Understanding Vibration and Its Impact 04:47 The Apollo Neuro Device 08:44 Using Apollo for Different States 11:41 Apollo in Psychedelic Therapy 24:32 Clinical Trials and Studies on Apollo 29:32 Heart Rate Variability and Biohacking 33:02 Revolutionizing Sleep with Apollo 34:40 Apollo’s Long-Term Effects and Dependency 37:16 Apollo’s Impact on ADHD and Psychiatric Disorders 45:22 The Importance of Human Connection and Simple Solutions 49:56 Longevity, Healthspan, and Future Innovations 57:23 Final Thoughts and Discount Offer See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 13

Your Brain is Lying to You—Here’s How to Take Back Control Every day, your brain is running subconscious scripts—hidden mental loops that shape your decisions, habits, and even your self-worth. But what if those loops are sabotaging you? In this episode, Bizzie Gold , mind architect and creator of The Break Method , joins Dave Asprey to expose the self-deception patterns controlling your thoughts —and how to reprogram your brain for true transformation . Bizzie’s method isn’t just another self-help philosophy. It’s science-backed , no BS , and engineered for results . From subconscious conditioning to emotional addiction cycles, you’ll learn the exact framework for breaking free from limiting beliefs and upgrading your mind. What You’ll Discover in This Episode: • The hidden mental loops sabotaging your success (and how to break them) • The science of self-deception —why your brain lies to you daily • How early childhood experiences hardwire your thoughts and emotions • The brain’s rejection vs. abandonment patterns —which one rules you • How to use E.L.I. questions to disrupt negative thinking instantly • The AI-powered brain upgrade that could change self-improvement forever If you’ve ever felt stuck in repetitive thought patterns, bad habits, or emotional cycles , this episode will give you the blueprint to take back control of your mind . Listen now—because your brain won’t fix itself. SPONSORS -Omni-Biotic | Visit omnibioticlife.com/dave and use code DAVE20 for 20% off. -Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Bizzie Gold’s Instagram : https://www.instagram.com/bizziegold/ • Bizzie Gold's Website : https://bizziegold.com/ • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 – Trailer • 00:28 – Intro • 01:39 – Understanding self-deception and its impact • 05:41 – The role of childhood trauma in shaping perception • 14:20 – Brain pattern spectrum and human behavior • 22:26 – Spiritual perspectives on DNA and past lives • 34:45 – Sharing knowledge from the ether • 34:54 – A surprising encounter with a professor • 35:43 – Healing and accessing intuition • 36:39 – The power of intuition in practice • 38:15 – Spiritual technology and Big Pharma • 39:54 – The role of self-trust in intuition • 40:49 – Understanding instinct vs. intuition • 42:17 – The E.L.I. framework for intuition • 45:50 – Hacking the brain’s language system • 57:04 – Parenting for emotional resilience • 01:06:13 – AI and emotional hacking • 01:11:01 – Conclusion and final thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 11

Is the Way You Speak Limiting How You Think? For years, scientists debated how language shapes the brain, but new research reveals it goes far beyond communication. Some languages lack numbers, grammar, or even complex sentences—yet their speakers navigate reality in ways that defy expectations. In this mind-bending episode, linguist Daniel Everett, known for challenging Noam Chomsky’s theories, shares how his time with the Pirahã people reshaped our understanding of language, cognition, and even consciousness. If language rewires thought, what happens when AI starts using it? Can a machine truly think? And what if whales, with their massive brains, have a language of their own? What You’ll Discover in This Episode: • The hidden power of language—why learning a new one literally reshapes your brain • The Piraha people’s mind-blowing approach to communication and what it reveals about human thought • Can AI truly “think” in language, or is it just an advanced mimic? • How your environment affects memory, navigation, and cognitive function • The psychedelic connection to language evolution—could altered states have unlocked speech? SPONSORS • Puori | Visit https://puori.com/dave and use code DAVE for 20% off. • BON CHARGE | Go to https://boncharge.com and use code DAVE for 15% off. Resources: • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Dan Everett’s Website: https://daneverettbooks.com/ • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 6

For decades, we’ve been told that our DNA is a fixed blueprint—an unchangeable code that dictates our health and lifespan. But what if that’s only half the story? Sharon Hausman-Cohen, a physician, researcher, and genomics expert at IntellxxDNA, joins Dave to reveal the cutting-edge science of genetic optimization —how understanding your DNA can unlock longer life, better brain function, and even protection from chronic disease. Forget the old-school genetic reports that left you with useless percentages. The new frontier of precision genomics goes beyond risk factors to actionable insights , showing you exactly how to turn on your body’s most powerful longevity genes and turn off the pathways driving inflammation, cognitive decline, and disease. What You’ll Learn in This Episode: • Why genetics alone don’t determine your future —and how to use epigenetics to control your health • The truth about MTHFR, APOE4, and other “bad” genes —are they actually harming you? • How genetic reports can predict and eliminate brain fog, fatigue, and pain • The hidden genetic reasons behind ADHD, depression, and anxiety —and how to fix them • Why some people age faster —and the one longevity gene that determines your biological age • Cutting-edge breakthroughs in DNA-based biohacking —is it possible to edit your genes for peak performance? This is the future of personalized medicine. By understanding your own genetic blueprint, you can stop guessing and start making the precise changes that will optimize your energy, brainpower, and lifespan! ** Visit IntellxxDNA at https://intellxxdna.com/asprey/ When you go to the website to find a clinician please select “human upgrade/longevity” as the type of consult to get specialized biohacking clinicians! ** SPONSORS -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. -Leela Quantum Tech | Head to https://leelaq.com/DAVE for 10% off. Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • IntellxxDNA Website : https://intellxxdna.com/asprey/ • 2025 Biohacking Conference : https://biohackingconference.com/2025 • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 – Intro • 02:00 – The Role of Genetics in Longevity • 03:37 – Gene Variants & Cognitive Health • 05:58 – Epigenetics vs. Genetics • 08:21 – Genomics & Pain Management • 09:26 – Breakthroughs in Genetic Research • 12:33 – The Future of Genomic Medicine • 14:27 – How to Use Genomic Reports • 38:25 – Mitochondria & Longevity • 42:40 – BH4 & Mental Health • 43:42 – Folinic Acid & Brain Function • 44:37 – Genomics & Autism • 46:06 – Personalized Medicine • 56:00 – APOE4 & Alzheimer’s Risk • 59:44 – Genetics & Heart Health • 01:04:54 – The Future of Precision Medicine • 01:20:23 – Conclusion & Next Steps See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 5

For years, we’ve been told that willpower and repetition are the keys to forming habits. But the truth is, habits don’t stick because of repetition—they stick because of emotion! In this all-time classic episode, Dave brings together two of the world’s top habit experts—BJ Fogg, PhD, and James Clear—to break down the real science of behavior change. BJ, the Stanford researcher behind Tiny Habits , explains why motivation, ability, and the right prompts are the real drivers of habits. Meanwhile, Atomic Habits author James Clear reveals how small decisions compound over time to shape your entire life. What You’ll Learn in This Episode: • Why willpower and repetition don’t work —and what actually makes habits stick • The tiny changes that create massive, lasting results • How emotions play a bigger role in habit formation than you think • The hidden power of stacking small habits for exponential growth • How to automate your decisions to free up brainpower for bigger goals SPONSORS -STEMREGEN | Head to https://www.stemregen.co/dave for 20% off your first order. -LMNT | Free LMNT Sample Pack with any drink mix purchase by going to https://drinklmnt.com/DAVE . Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • BJ Fogg’s Website – https://www.bjfogg.com/ • James Clear’s Website : https://jamesclear.com/ • 2025 Biohacking Conference : https://biohackingconference.com/2025 • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 – Intro • 00:39 – Understanding habits • 01:10 – Layering habits with James Clear • 01:49 – BJ Fogg’s Tiny Habits method • 03:03 – The science of habit formation • 05:49 – Practical habit-building tips • 09:57 – Emotions vs. repetition in habits • 18:02 – Ability & context in habits • 21:19 – Genes, dopamine & behavior • 26:20 – Final thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Feb 27

In this first-ever AMA episode, Dave tackles your biggest biohacking questions—straight from The Upgrade Collective ! From optimizing brain power to pushing the limits of cold therapy, this episode is packed with cutting-edge hacks to supercharge your body and mind. If you’d like to have your questions answered on the next AMA, click the link below for details on The Upgrade Collective membership, and get all sorts of extra biohacking add-ons for your life! In today’s episode: What if you could amplify oxytocin—the “love hormone”—to build stronger relationships and lower stress? Or upgrade your cold plunge routine for max benefits in less time? Dave reveals the science behind these powerful biohacks, plus his take on rapamycin for longevity, the right way to supplement for thyroid health (without a prescription), and even how he personally overcame Asperger’s traits through neuroplasticity and mitochondrial upgrades. There’s even some great advice for all the parents out there! What You’ll Learn: • How to naturally boost oxytocin for better relationships and emotional health • The fastest way to upgrade your cold plunge for heat shock benefits • Is rapamycin really a longevity miracle? Dave’s personal take • How mitochondria impact brain power, mood, and aging —and how to fix them today! • The shocking reason some people can’t process reality correctly (and how to retrain your brain) • The real truth about stem cells, exosomes, and V-cells for regeneration • The hidden dangers of selenium, thyroid supplements, and over-fasting SPONSORS -Puori | Visit https://puori.com/dave and use code DAVE for 20% storewide. -Calroy | Head to https://calroy.com/dave for an exclusive discount. Resources: • Upgrade Collective Membership : https://www.ourupgradecollective.com • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • 2025 Biohacking Conference : https://biohackingconference.com/2025 • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 – Intro • 00:37 – Welcome to the Human Upgrade AMA • 01:13 – Cold Plunges and Alpha Lipoic Acid for Health • 03:11 – Hot and Cold Therapy for Optimal Health • 07:29 – Understanding Thyroid Health and Treatment • 09:09 – The Importance of Selenium • 14:41 – Stem Cells vs. Exosomes • 16:27 – Rapamycin for Longevity • 18:07 – Asperger’s Syndrome and Neuroinflammation • 28:53 – Understanding Asperger’s and Self-Awareness • 29:24 – The Challenge of Offering Help • 30:06 – The Importance of Reconnection Work • 31:34 – Personal Development Journey • 34:42 – The Role of Emotions in Biohacking • 35:55 – Dealing with Flashbacks and Trauma • 45:46 – The Power of Oxytocin • 49:48 – The Truth About Kale and Oxalates • 54:25 – Teaching Kids to Regulate Their Nervous System See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Feb 25

Can You Mimic Fasting—Without Actually Fasting? Chris Rhodes, a biochemist and longevity researcher, joins Dave to reveal a groundbreaking fasting mimetic that could revolutionize how we approach aging, metabolism, and health. Fasting is one of the most powerful tools for longevity, but what if you could achieve the same benefits without hunger, energy crashes, or social sacrifices? Scientists have identified key compounds that mimic fasting at the cellular level—offering a way to extend lifespan, boost metabolism, and enhance cognitive function without giving up food. Enter Mimio, a blend of four key molecules naturally produced during fasting, is engineered to deliver the life-extending benefits of fasting—without starvation. For decades, fasting has been the gold standard for longevity, but over-fasting can wreck hormones, metabolism, and muscle mass. So, what if you could get the benefits of a 36-hour fast without the downsides? Chris breaks down the science behind fasting, autophagy, and the game-changing compounds that trick your body into entering a fasted state— even while eating. What You’ll Learn: • The optimal fasting window for maximizing lifespan (Hint: It’s not 16 hours) • The four fasting metabolites that extend life by 96% • How Mimio mimics fasting benefits—without giving up food • The real reason over-fasting destroys your metabolism and hormones • Why traditional longevity drugs (Metformin, Rapamycin) fall short • Can you build muscle and burn fat at the same time? The science of mTOR & AMPK • Why Big Pharma doesn’t want you to know about this breakthrough *** Get 20% off Mimio at mimiohealth.sjv.io/3J9abX with code: DAVE *** Sponsors: Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Mimio Instagram: https://www.instagram.com/mimiohealth/ • Mimio Website : https://mimiohealth.com/ • 2025 Biohacking Conference : https://biohackingconference.com/2025 • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: • 00:00 – Intro • 00:58 – Fasting & Longevity • 01:88 – Optimal Fasting Length • 03:39 – Alternate Day Fasting: Pros & Cons • 05:50 – Key Fasting Compounds • 07:34 – Spermidine & Longevity Molecules • 11:41 – FDA Roadblocks on Natural Compounds • 15:37 – AI, Big Data & Longevity Research • 31:19 – Mimio’s Impact on Testosterone & Aging • 35:16 – Longevity & Death Philosophy • 36:48 – Biohacking Origins • 37:03 – Metabolism & Cognitive Function • 38:35 – Unexpected Effects of Fasting • 40:43 – Fasting & Circadian Rhythms • 43:09 – Mimio Science & Benefits • 45:14 – Mimio in a Daily Routine • 55:05 – Men vs. Women: Fasting Differences • 01:02:23 – Future of Nutrition & Biohacking • 01:07:21 – Conclusion & Discount Code See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Feb 21

Could a single molecule be the difference between vibrant longevity and early decline? Dr. Andrew Salzman—Harvard-trained physician, scientist, and creator of the first PARP1 inhibitor, Chief Medical Officer of Wonderfeel—joins Dave to reveal the real key to living longer, fighting disease, and maximizing your energy: NAD. This master molecule fuels your mitochondria, DNA repair, and cellular resilience , but here’s the catch—it plummets as you age. That means more fatigue, brain fog, inflammation, and higher risks of disease. But what if you could stop the decline and even reverse it? Dr. Salzman breaks down the game-changing science behind NAD, CD38, and cellular repair —and the fastest, most effective ways to optimize your levels for peak performance, health, and longevity. Get ready to rethink everything you thought you knew about aging, pharmaceuticals vs. supplements, and the radical new approach to living better, longer. What You’ll Learn: • The #1 reason your NAD is disappearing—and how to fix it • Why NAD is the missing link in energy, DNA repair, and disease prevention • The hidden enzyme (CD38) that’s sabotaging your longevity • How to supercharge mitochondria, optimize blood flow, and fight aging at the source • Why the supplement industry has it wrong—and the best way to boost NAD naturally • The shocking truth about the FDA, pharmaceuticals, and the future of anti-aging medicine Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Wonderfeel Instagram – https://www.instagram.com/getwonderfeel/ • Wonderfeel Supplement : https://getwonderfeel.com/product/wonderfeel-youngr-nmn/?utm_source=Dave&utm_medium=podcast • 2025 Biohacking Conference : https://biohackingconference.com/2025 • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com Timestamps: 00:00 Trailer 01:07 Introduction and Episode Overview 02:29 Meet Dr. Andrew Salzman 02:36 From Physician to Researcher 03:39 Pharmaceuticals vs. Nutritionals 04:17 The Role of NAD in Longevity 06:32 Challenges in Longevity Research 12:58 Understanding NAD and PARP 14:34 NAD’s Impact on Health 23:19 Gut Health and Longevity 27:43 Innovations in NAD Supplementation 41:27 Customer Feedback and Product Effectiveness 42:41 Surprising Benefits of NAD for Sexual Health 44:47 NAD and Vascular Health 48:46 NAD’s Role in Aging and Longevity 54:03 NAD and Lifestyle Choices 01:03:02 NAD and Cognitive Function 01:06:18 NAD and Exercise 01:13:42 NAD and Sleep 01:21:54 Final Thoughts on NAD and Longevity See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Feb 20

Welcome to the metabolism masterclass! Dr. Ben Bikman (Ph.D Professor BYU), a powerhouse in metabolism science, joins Dave to expose the truth about insulin resistance —the silent epidemic fueling obesity, chronic disease, and low energy. Forget the outdated calorie-counting nonsense (it doesn’t work)—Dr. Bikman reveals how your hormones, not just your diet, control your metabolism and what you can do to reset it fast. From debunking diet myths to uncovering why some people can eat 400 grams of carbs and never gain fat (hint: it’s not what you think), this episode unpacks the real science of fat storage, energy, and optimal health. Get ready for mind-blowing insights, metabolic hacks, and a new way to think about food, fasting, and longevity. What You’ll Learn: • The #1 driver of insulin resistance—and why most doctors miss it • Why eating more fat (yes, really) could be the key to reversing metabolic dysfunction • How fasting, cold therapy, and red light impact your metabolism • The truth about carbs, seed oils, and why some people can’t gain fat • How to tell if insulin resistance is wrecking your energy & health Resources: • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Benjamin’s new book How Not To Get Sick : https://a.co/d/aADlMWv • Benjamin’s YouTube Page – https://www.youtube.com/@benbikman • 2025 Biohacking Conference : https://biohackingconference.com/2025 • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com SPONSORS: -Lumiram | Go to http://healthlighting.com/dave to save 10% on your order. -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Timestamps: 00:00 Trailer 00:52 Introduction to Dr. Benjamin Bikman 02:20 The Battle Against Conventional Dietetics 04:12 Understanding Insulin Resistance 06:29 The Two Paths to Insulin Resistance 10:19 Fasting and Metabolic Health 14:11 Insulin and Cognitive Enhancement 18:16 Identifying Insulin Resistance 30:12 The Role of Insulin in Fat Storage 42:04 Understanding Glucose and Insulin Dynamics 42:26 The Role of Exercise in Glucose Regulation 42:54 AMPK and Muscle Contraction 45:21 Calories In, Calories Out Debate 46:15 The Myth of Calorie Counting 50:13 Ketosis and Metabolic Rate 51:14 Intermittent Fasting and Muscle Preservation 55:21 Insulin Resistance and Ketogenic Diets 01:02:04 Circadian Rhythm and Insulin Sensitivity 01:08:08 Environmental Toxins and Insulin Resistance 01:13:03 The Impact of Seed Oils on Insulin Resistance 01:19:22 Final Thoughts and Resources See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Feb 18

Most people wait for inspiration. But what if you could train your brain to create on demand? Rick Rubin has spent decades shaping the sound of legendary artists—Jay-Z, Johnny Cash, Metallica, and countless others—by tapping into the unseen forces of creativity. But what’s the secret behind his genius? In this must-listen episode, Rick sits down with Dave to explore the science and soul of creativity , revealing how meditation, mindfulness, biohacking, and unconventional thinking fuel artistic breakthroughs. From rewiring your brain with meditation to stacking biohacks for peak creative flow, Rick shares the techniques that have kept him at the top of the music industry for over 40 years. Dave and Rick go deep on the mental and physiological hacks that enhance creative performance , the surprising link between biohacking and artistry, and the rituals that keep Rick sharp, focused, and endlessly inspired. What You’ll Learn: • How Rick Rubin taps into creative flow—and how you can too • The surprising connection between meditation and peak artistic performance • Why biohacking isn’t just for longevity—it’s for creative mastery • Rick’s favorite tools for mental clarity, focus, and creative breakthroughs • The real secret behind working with the world’s biggest artists • How to cultivate an environment that fuels creativity Resources: • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Rick’s New Book The Creative Act: A way of Being: https://a.co/d/2bLbjeS • Rick’s Instagram: https://www.instagram.com/rickrubin/?hl=en • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com SPONSORS: Omni-Biotic | Visit omnibioticlife.com/dave and use code DAVE20 for 20% off. BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 for 20% off your first order of PerfectAmino. Timestamps: • 00:00 – Trailer • 00:51 – Intro to Rick Rubin • 02:51 – Rick’s Musical Journey • 03:06 – The Creative Process • 08:31 – Biohacking & Sensitivity • 13:46 – Meditation & Creativity • 19:37 – Rick’s Weight Loss Story • 29:21 – Eating Habits & Rhythm • 29:55 – Advanced Biohacking • 31:23 – Oxygen Therapy & Carbogen • 35:16 – Peptides & Longevity • 45:59 – Prayer, Gratitude & Performance • 51:03 – Reflections on Life & Mortality See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Feb 13

What’s keeping you stuck in a scarcity mindset instead of stepping into abundance? What truly sets successful people apart from those who struggle? Tony Robbins has spent decades answering these questions—coaching billionaires, world leaders, elite athletes, and everyday people to master their money, mindset, and mission. In this all-time classic podcast, he shares the hard-hitting truths about financial freedom, why fear is your biggest enemy, and how to break free from the psychological traps that keep you stuck. Tony and Dave dive deep into the wealth-building playbook that the world’s top investors use (including Warren Buffett, Ray Dalio, and Paul Tudor Jones), plus the biohacks and routines that fuel Tony’s legendary stamina. From the real secret to compounding wealth to stem cell breakthroughs that could change human longevity , this episode will shift the way you think about money, health, and success. Most people dream of financial freedom, but few actually achieve it. What’s holding you back—and how can you break through? What You’ll Learn: • The biggest mistake people make with money (and how to avoid it) • The mindset of the ultra-wealthy —how top investors think differently • Why fear is your greatest enemy in investing and personal success • The three essential money buckets —security, growth, and dreams • Tony’s top biohacks for insane energy and peak performance • The real secret to happiness and fulfillment (it’s not what you think) Resources: • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Tony’s Website: https://www.tonyrobbins.com/ • Tony’s Instagram: https://www.instagram.com/tonyrobbins/?hl=en • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com SPONSORS: -Puori | Visit https://puori.com/dave and use code DAVE for 20% storewide. -fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Timestamps: • 00:00 Intro • 00:50 Meet Tony Robbins • 02:18 Financial Wisdom & Motivation • 05:43 Psychology of Wealth • 10:10 Investment Strategies • 15:24 Balancing Money & Experiences • 21:21 Power of Giving • 30:06 Paying for College • 31:00 Commitment & Success • 31:53 Energy & Biohacks • 35:12 Cryotherapy & Inflammation • 38:54 Stem Cells & Regeneration • 41:59 Financial Freedom • 46:35 Wnt Pathway Breakthroughs • 52:35 Health & Longevity • 56:34 Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Feb 11

From chart-topping hits to life-threatening lows—how did Timbaland go from producing for Jay-Z, Beyoncé, and Justin Timberlake to battling addiction and obesity? And more importantly, how did he take his life back? In this raw and revealing conversation, music icon Timbaland shares the blueprint behind his incredible transformation—how he broke free from opioid addiction, lost 130 pounds, and rewired his mindset for long-term success. He and Dave dive into the power of discipline, the dangers of quick fixes, and the hard truths about personal transformation. Timbaland opens up about the mental shift that saved his life , how he kicked a high-dose opioid habit cold turkey, and why his new “drug” of choice is something anyone can access. Most people want change, but few actually achieve it. What separates those who succeed from those who stay stuck? And how can you apply Timbaland’s hard-earned lessons to your own life? What You’ll Learn: • The #1 mindset shift that made weight loss & addiction recovery possible • Why self-discipline beats willpower —and how to build it like a muscle • The real reason most diets fail —and what actually works • The truth about opioid addiction and recovery —why most people never escape • How your daily habits shape your future —and how to change them fast • The shocking link between addiction, metabolism & long-term health • How Timbaland stayed clean without rehab —and why relapse wasn’t an option We’d like to extend our gratitude to Eudēmonia for providing the opportunity to record with Timbaland at their event. Eudēmonia, created by the founders of Wanderlust Festival, is a premier health and well-being summit. You can learn more about their initiatives and upcoming events here: https://wanderlust.com/ Resources: • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Timbaland’s Website: https://www.timbaland.com/ • Timbaland’s Instagram : https://www.instagram.com/timbaland/?hl=en • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com SPONSORS: -STEMREGEN | | Head to https://www.stemregen.co/dave for 20% off your first order. -Leela Quantum Tech | Head to https://leelaq.com/DAVE for 10% off. Timestamps: • 00:00 Trailer • 00:00 Introduction to the Human Upgrade • 00:09 Timbaland on Passion and Energy • 00:42 Balancing Passion and Avoiding Burnout • 02:04 Dreams and Manifestations • 04:51 Overcoming Addiction • 05:59 The Role of God in Recovery • 09:28 Helping Others with Addiction • 14:00 Weight Loss and Health Transformation • 16:29 Trusting Your Body’s Signals • 18:45 Skepticism About Modern Products • 21:10 Exploring Longevity and Individual Health • 22:23 The Intersection of Music and Spirituality • 25:56 Understanding Synesthesia and Its Impact • 27:41 The Journey to Weight Loss and Fitness • 35:08 The Importance of Sleep and Health • 37:23 Final Thoughts and Reflections See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Feb 6

Could the right form of a single vitamin be the difference between thriving and barely surviving? In this Part 2 conversation, human biologist and longevity expert Gary Brecka reveals the #1 overlooked factor that’s wrecking your health: methylation —your body’s ability to convert nutrients into fuel. If this process fails, your hormones, energy, and even mental health take a nosedive. Gary and Dave dive deep into the real cause of anxiety, ADHD, and mood disorders , the hidden genetic reason why diets fail , and why Big Pharma isn’t talking about this critical health breakthrough. Are you unknowingly setting yourself up for disease? What’s the simple fix that can reverse anxiety, gut problems, and even prevent genetic disease? And why is your doctor ignoring one of the biggest markers of longevity? What You’ll Learn: • The MTHFR gene mutation —and why it’s quietly affecting millions • Anxiety, ADHD, and depression —why these disorders start in your cells, not your brain • The gut-brain connection —how your microbiome controls your mood • Why your “healthy diet” might be hurting you (and what to eat instead) • How nutrient deficiencies are passed from mother to child —and how to stop it • The truth about homocysteine —the blood marker that could predict your lifespan • Why most people are living at 50% capacity —and how to get your energy back Resources: • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Gary Brecka’s Website: https://bit.ly/4hlfyti • Gary Brecka’s YouTube: https://bit.ly/3E3Aaba • Gary Brecka’s Instagram: https://bit.ly/3PNsgFe • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com • The Mold Movie!: https://moldymovie.com/ SPONSORS: -BON CHARGE | Go to https://boncharge.com/ and use coupon code DAVE to save 15%. -Qualia | Go to https://www.qualialife.com/dave15 to get an additional 15% off subscriptions. Timestamps: • 00:00 Trailer • 00:31 What Is Methylation? • 01:37 MTHFR, Folate & Your Health • 04:17 How Methylation Affects Disease • 06:41 Nutrient Deficiencies & Health Risks • 07:09 Why Blood Work Matters • 11:44 Homocysteine & Heart Health • 21:37 Catecholamines & Anxiety • 34:28 The Link Between Nutrients & Mood • 34:48 How Catecholamine Ratios Affect Mental Health • 35:39 Personal Health Struggles & Lessons • 36:25 The Role of Methylation in Wellness • 37:57 Methylation & Relationship Dynamics • 39:49 Hidden Dangers of Mold Toxicity • 52:55 Hydrogen Water for Health • 01:01:19 Mitochondria’s Role in Longevity • 01:02:23 Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Feb 5

Why were our grandparents stronger, healthier, and living longer—without the “advancements” of modern medicine? Gary Brecka, one of the world’s leading experts in human longevity and performance, exposes the hidden crisis that’s wrecking your hormones, slashing your energy, and cutting your lifespan short. In this no-holds-barred conversation with Dave Asprey, they break down the corporate greed, medical corruption, and environmental toxins designed to keep you sick, weak, and dependent. What’s really causing the testosterone collapse in men and women? How is AI changing the game for hormone optimization, biohacking, and personalized health ? And why are we aging faster than ever —while Big Pharma profits? This first episode in a two-part series is a deep dive into hormone optimization, testosterone, cholesterol myths, longevity hacks, and the AI-driven future of health. What You’ll Learn: • Why testosterone levels are plummeting —and how to restore them naturally • The real reason life expectancy is dropping (hint: it’s not just diet) • The Kellogg conspiracy —how food was designed to lower libido & testosterone • Why mainstream medicine is failing you (and what to do instead) • How AI and big data are rewriting the rules of health & longevity in • The shocking truth about cholesterol, heart disease, and pharmaceuticals • Why functional medicine & biohacking hold the key to real health optimization Resources: • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Gary Brecka’s Website: https://bit.ly/4hlfyti • Gary Brecka’s YouTube: https://bit.ly/3E3Aaba • Gary Brecka’s Instagram: https://bit.ly/3PNsgFe • Dave Asprey’s New Book - Heavily Meditated : https://daveasprey.com/heavily-meditated/ • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com SPONSORS: Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Apollo Neuro | To get an Apollo wearable, go to https://apolloneuro.com/Dave and save 15%. Timestamps: • 00:00 – Trailer • 00:42 – Introduction to The Human Upgrade • 01:35 – Meet Gary Brecka • 03:32 – Performance vs. Longevity • 06:16 – The Importance of Testosterone • 15:11 – Historical Hormone Levels • 18:00 – Population Averages in Health • 18:51 – The Flaws of Grading on a Curve • 20:35 – Corporate Influence on Health • 21:04 – The Danger of Cumulative Dosage • 22:20 – Social Media & Public Perception • 25:19 – Independent Research Matters • 32:21 – Big Data & AI in Health • 36:02 – The Future of Personalized Medicine • 36:49 – Conclusion & Teaser for Part Two See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jan 30

Billy Carson, a Harvard-certified expert in ancient civilizations and an MIT-trained scholar in neuroscience, has spent decades decoding the mysteries of lost technology, quantum reality, and human optimization. Alongside Elisabeth Carson, a biohacker and neuroscience researcher, they bridge the gap between ancient wisdom and modern science—revealing secrets that could transform your mind, body, and reality. What if the Great Pyramid wasn’t just a monument but a powerful energy device designed to amplify human potential? What if ancient civilizations understood frequency, grounding, and longevity in ways modern science is only beginning to grasp? In this episode, the Carsons connect the dots between lost technology, bioenergetics, and conscious relationships , showing how these ancient systems align with the latest research on vibrational healing, mitochondrial energy, and peak performance. They explore how quantum fields influence cellular regeneration , why high-frequency living affects health and relationships, and how suppressed knowledge could redefine the future of wellness. What You’ll Learn: • How the Great Pyramid functioned as an energy generator—and how to apply its principles to longevity • The forgotten science of frequency and its effects on health, aging, and vitality • How quantum energy and grounding can optimize mitochondrial function • The connection between biohacking, consciousness, and relationships • Why suppressed ancient knowledge holds the key to true human potential Resources: • 2025 Biohacking Conference : https://biohackingconference.com/2025 • 4biddenknowledge YouTube – https://www.youtube.com/@ForbiddenKnowledge1 • 4biddenknowledge Website – https://www.4biddenknowledge.com/ • Billy Carson Instagram – https://www.instagram.com/4biddenknowledge/?hl=en • Elisabeth Carson Instagram - https://www.instagram.com/elisabethicarson/?hl=en • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Book – Smarter Not Harder : https://daveasprey.com/books • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com SPONSORS: Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. Timestamps: • 00:00 Trailer • 00:39 Meet Dave Asprey • 02:16 Trauma, Success & Relationships • 04:22 Billy & Elizabeth Carson on Growth • 10:09 Birth & Pre-Natal Trauma • 19:30 Healing & Biohacking • 23:16 Relationships & Triggers • 28:35 Vitamin D & Nutrients • 35:25 Empathy & Intuition • 37:24 Manifestation • 41:25 Neuroscience & Altered States • 53:04 Ancient Wisdom & Biohacking • 57:45 Ancient Technologies • 01:08:26 Giants & Six Fingers • 01:08:58 Sumerian Artifacts • 01:10:28 Hidden Agendas • 01:13:32 Hypnosis Revelations • 01:19:21 Power of Intuition • 01:30:11 Love & Self-Discovery • 01:35:52 Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jan 28

Everything you’ve been told about weight loss is a lie! In this episode, Dr. Nick Norwitz, a metabolic health expert with accolades from Oxford and Harvard, joins Dave to expose the biggest myth in dieting: Calorie Counting. Together, they dismantle outdated weight-loss advice and reveal the truth about metabolism that could revolutionize your health. Dr. Norwitz shares cutting-edge science and personal stories that challenge the “eat less, move more” narrative, uncovering why traditional dieting often fails—and what actually works. From the role of ketosis in healing chronic illness to the surprising ways fasting affects hair loss, metabolism, and inflammation, this episode is packed with actionable insights that you won’t hear anywhere else. You’ll also learn how viruses might be fueling food addiction, why gut health is the missing key to metabolic recovery, and how new research could unlock the future of personalized medicine. If you’ve ever felt like your metabolism was holding you back, this conversation will give you the tools to take control of your health for good. What You’ll Learn: • Why calorie counting is useless—and the better way to lose weight • The shocking truth about how your metabolism ACTUALLY works • How ketosis and fasting can heal inflammation and chronic disease • The role of gut health and microbiome diversity in weight loss • New research on food addiction and its surprising link to viruses • Why individualization is the key to sustainable health Resources: • 2025 Biohacking Conference : https://biohackingconference.com/2025 • Nick Norwitz’s YouTube – https://www.youtube.com/@nicknorwitzPhD • Nick Norwitz’s Website – https://www.nicknorwitz.com/ • Follow Nick on Instagram – https://www.instagram.com/nicknorwitz/ • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Book – Smarter Not Harder : https://daveasprey.com/books • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com SPONSORS: Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Timestamps: • 00:00 Trailer • 00:39 Meet Dr. Nick • 04:44 Nick’s Health Journey • 07:54 Keto Diets • 09:37 Modern Medicine Challenges • 13:31 Exercise vs. Diet • 14:32 Obesity Memory • 17:36 Keto Cycling • 20:51 Microbiome Health • 26:26 Fasting & Hair Loss • 34:56 Alzheimer’s Insights • 45:11 Cold Plunge Benefits • 45:43 Dopamine Boosts • 46:26 Cold Plunge & Inflammation • 47:15 Best Time to Cold Plunge • 48:18 Pain & Dopamine • 49:31 Exercise & Stress • 51:49 Cholesterol & Inflammation • 01:05:42 Debunking Calories In/Out • 01:07:09 Food Addiction • 01:11:15 Metabolic Health Tips • 01:24:13 Nick’s Mission See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jan 23

What if the key to living longer isn’t avoiding stress—but mastering it Jeff Krasno, founder of Commune and renowned stress expert, joins Dave to reveal why most of us have stress all wrong. In this fascinating conversation, Jeff redefines how we think about stress—showing how it can be your greatest ally instead of your worst enemy. From his groundbreaking new book Good Stress to the ancient practices that have stood the test of time, Jeff shares how to unlock the hidden potential of stress to build resilience, foster connections, and boost longevity. You’ll discover why crying is an emotional biohack, how to spot the fine line between good and bad stress, and why the modern world keeps us stuck in a chronic stress loop—and how to break free. Jeff also dives into the science of emotional regulation, the role of connection in health, and the radical power of embracing discomfort to create balance and ease in your life. What You’ll Learn: • How to turn stress into a tool for resilience and longevity • Why Jeff calls chronic ease the root of modern disease • The science of tears: how crying regulates stress and boosts health • How you can build a “psychological immune system” for emotional regulation • The key to balancing good stress and avoiding burnout • Why discomfort is the path to growth—and how to embrace it Resources: • 2025 Biohacking Conference : https://biohackingconference.com/2025 • Jeff Krasno’s Website – https://www.jeffkrasno.com/ • Preorder Good Stress – https://www.onecommune.com/goodstressbook#preorder • Follow Jeff on Instagram – https://www.instagram.com/jeffkrasno • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Book – Smarter Not Harder : https://daveasprey.com/books • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com SPONSORS: Puori | Visit https://puori.com/dave and use code DAVE for 20% storewide. Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. Timestamps: • 00:00 – Intro • 01:02 – Meet Jeff Krasno • 02:16 – Topanga Fires Survival • 04:14 – Good Stress vs. Bad Stress • 06:14 – Cortisol’s Role in Stress • 13:13 – Social Media Triggers • 20:32 – Stressful Conversations • 31:34 – Cold Therapy Benefits • 42:26 – Stress and Recovery Balance • 45:58 – High Altitude Training • 47:29 – Cold Therapy Fails • 49:42 – Science of Crying • 54:51 – Reflections on Legacy • 59:37 – Balancing Stress and Ease • 01:10:30 – Nature and Spirituality • 01:22:52 – Facing Death with Grace • 01:32:53 – Closing Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jan 21

What if you could cheat aging, indulge in life’s guilty pleasures, and still thrive? Dr. Sandra Kaufmann, a pioneering longevity expert and fearless explorer of the biochemical frontier, joins Dave to reveal how you can bend the rules of biology to live longer, smarter, and stronger. Forget perfection—Dr. Kaufmann’s radically practical approach embraces the human side of longevity, showing you how to optimize your body while enjoying the ride. From downing Diet Cokes to defying traditional medical dogma, she’s rewritten the playbook on anti-aging with her Seven Tenets of Aging . Together, she and Dave dive into everything from molecular hacks for outsmarting junk food to unlocking the secret power of your mitochondria, DNA, and circadian rhythms. This episode goes beyond the surface with mind-blowing insights, hilarious moments, and actionable steps to take your health (and your fun) to the next level. What You’ll Learn: • The Seven Tenets of Aging and how they’ll change your approach to health • Why indulging in “bad” habits doesn’t have to sabotage your longevity • Biochemical secrets to combat oxidative stress, glycation, and cellular junk • The real story behind NAD, circadian rhythms, and the tools for better sleep • How to create a personalized health plan that’s sustainable, effective—and fun Resources: • Supplement Protocol One-Sheet for this episode: https://www.instagram.com/dave.asprey/?hl=en • 2025 Biohacking Conference : https://biohackingconference.com/2025 • Kaufmann Protocol Website : https://kaufmannprotocol.com • Sandra Kaufmann’s Book – Why We Age and How to Stop It: https://www.amazon.com/Kaufmann-Protocol-Why-Age-Stop/dp/0692089047 • Sandra Kaufmann’s Instagram: https://www.instagram.com/kaufmannantiaging/?hl=en • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Book – Smarter Not Harder : https://daveasprey.com/books • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com SPONSORS: Leela Quantum | Head to https://leelaq.com/DAVE for 10% off. Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Timestamps: • 00:00 Trailer • 00:45 Guest Introduction • 02:30 Longevity Insights • 04:22 Personal Stories • 08:00 Pharmaceuticals • 12:26 Diet and Lifestyle • 18:19 Seven Tenets • 22:04 Sleep and Circadian Rhythms • 26:41 NAD and Supplements • 37:46 Blood Sugar and AGEs • 47:09 Microcirculation • 49:08 NRS and Imports • 49:18 Celebrex Medication • 50:03 Celebrex Benefits • 50:41 Alzheimer’s and Celebrex • 51:28 Antioxidants • 54:26 Stem Cells and Exosomes • 58:03 Laser Skin Treatments • 01:07:34 Hormones and Longevity • 01:20:03 Lithium for Mood • 01:27:45 Gender and Longevity • 01:32:39 Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jan 16

Is there actual “magic” on this planet, or is it just in the movies? Dr. Barry Morguelan, a top surgeon and one of only nine living grandmasters of an ancient Lao Tzu lineage, joins Dave to share secrets that have been hidden for 5,000 years. Together, they explore how the principles behind quantum physics, energy mastery, and timeless healing techniques can revolutionize your health, mindset, and life. From breaking rocks with energy to healing broken bones with focused intent, Dr. Barry reveals the extraordinary power of the “Great 8” — a framework to unlock your potential in relationships, creativity, health, intelligence, and more. This episode is packed with incredible stories, actionable wisdom, and a secret GIFT to help you start your own journey toward unparalleled vitality and longevity! What You’ll Learn: • The 8 ancient secrets to mastering energy, healing, and peak performance • How you can harness quantum physics for success • Why energy techniques can REVERSE aging and boost health naturally • The science of serendipity and how you can harness it daily • How to grow stronger, smarter, and healthier every day with simple practices Resources: • 2025 Biohacking Conference : https://biohackingconference.com/2025 • Follow Dr. Barry on Instagram : https://www.instagram.com/energyforsuccess.official?igsh=eGcwZWhid3Q1M2Rm&utm_source=qr • Explore the Great 8 and Get Your Free Gift : https://energyforsuccess.com/dave/ • Learn More About Energy Practices : https://energyforsuccess.com/ • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Book – Smarter Not Harder : https://daveasprey.com/books • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com SPONSORS: - Lumiram | Go to http://healthlighting.com/dave to save 10% on your order. - Calroy | Head to https://calroy.com/dave for an exclusive discount. Timestamps: • 00:00 Trailer • 01:10 Introduction to Dr. Barry and His Journey • 06:16 The Turning Point: Mrs. Rodriguez’s Story • 09:04 Exploring Alternative Medicine Around the World • 13:02 Discovering Ancient Chinese Healing Techniques • 16:39 The Power of Quantum Physics and Lao Tzu’s Teachings • 27:25 Personal Experiences with Energy Healing • 36:35 The Great Eight: Structuring Your Day for Success • 36:51 Introduction to Energy for Success • 37:17 Understanding the Great Eight • 38:23 The Matrix and Animal Brain • 44:39 The Importance of Serendipity • 49:35 Four Categories of People • 53:02 Personal Experiences and Lessons • 58:34 The Power of Energy Practices • 01:07:06 Conclusion and Call to Action See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jan 14

What happens when nearly 60 years of combined biohacking expertise collide in one podcast? Peter Diamandis is a world-renowned futurist, space entrepreneur, and innovator behind groundbreaking ventures like the XPRIZE and Abundance 360. Dave sits down with Peter to combine their nearly 60 years of biohacking expertise, delivering the ultimate playbook for living longer and healthier. They dive into revolutionary AI-driven health solutions, mindset shifts that fuel vitality, and practical routines you can start today. Peter, the author of The Longevity Guidebook , shares deeply meaningful tools and tips to expand your healthspan for decades to come. What You’ll Learn: • The top AI tools reshaping health and longevity • Simple daily habits that improve energy, sleep, and brain performance • Why mindset is the key to adding years to your life • The cutting-edge science of age reversal and functional health • How Peter and Dave biohack their routines for peak performance Resources: • 2025 Biohacking Conference : https://biohackingconference.com/2025 • Peter Diamandis’s New Book : https://longevityguidebook.com/home-blk-nav • Peter Diamandis’s Website : https://www.diamandis.com/ • Peter Diamandis’s Purpose Finder (MTP) : https://purposefinder.ai/ • Danger Coffee : https://dangercoffee.com • Dave Asprey’s Website : https://daveasprey.com • Dave Asprey’s Book – Smarter Not Harder : https://daveasprey.com/books • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live : https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com • Upgrade Labs : https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement : https://40yearsofzen.com SPONSORS: -Omni-Biotic | Visit omnibioticlife.com/dave and use code DAVE20 for 20% off. -LMNT | Free LMNT Sample Pack with any drink mix purchase by going to drinklmnt.com/dave . Timestamps: • 00:00 Open • 00:53 Introduction to Peter Diamandis • 01:54 Peter’s Longevity Journey • 03:26 Tracking Sleep and Biohacking • 05:49 The Importance of Deep Sleep • 07:22 Thinking Big and Longevity • 10:36 Russian Innovations in Sleep • 25:29 AI and Longevity • 29:01 Gene Editing and Epigenetics • 35:13 Light Therapy and Routines • 43:07 Gut Health and Endotoxins • 44:17 Exploring Conscious Pain Practices • 45:51 Hacking Hot Tubs for Health Benefits • 46:28 The Science Behind Dopamine Reset • 46:43 Introduction to Fountain Life • 48:41 Advanced Diagnostics and AI Integration • 50:29 Therapeutics and Cutting-Edge Treatments • 51:41 The Evolution of Longevity Companies • 55:30 The Future of Longevity and Healthspan • 01:01:27 The Role of AI in Health and Longevity • 01:07:31 Personal Longevity Practices and Insights • 01:16:43 Finding Your Purpose for Longevity • 01:24:01 Final Thoughts and Resources See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jan 9

What if you could ditch your glasses forever by simply doing a 10-minute exercise each day? In this episode, Dave sits down with Dr. Bryce Appelbaum, a visionary in vision biohacking, to uncover how simple techniques can transform your eyesight. From near-far focusing to eye stretches, these exercises don’t just improve your vision—they enhance your brain’s performance, energy, and overall health. Dr. Bryce shares his own journey of overcoming severe vision challenges, the science behind vision training, and how anyone can rewire their brain for sharper sight. If you’re dealing with nearsightedness, eye strain, or just want to keep your eyes sharp as you age, this episode shares simple ways to improve how you see the world—literally! What You’ll Learn: • Why vision training is the next frontier in biohacking • Three free techniques to improve your vision naturally • How your eyesight affects brain performance and energy levels • Why kids and adults need to get outside for better eye health • How to train your eyes to stop relying on glasses Go to www.screenfit.com/enroll and use code DAVE ($200 OFF with the code) Or Visit myvisionfirst.com/dave/ for 5000$ off the premium concierge program! Sponsors Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Resources: • 2025 Biohacking Conference – https://biohackingconference.com/2025 • Screenfit - Visit https://www.screenfit.com/enroll and use code DAVE ($200 OFF with the code, from $497 to $297) • MyVisionFirst – Visit https://myvisionfirst.com/dave/ and apply now to get $5000 off • Danger Coffee – https://dangercoffee.com • Dave Asprey’s Website – https://daveasprey.com • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books • Dave Asprey’s Linktree – https://linktr.ee/daveasprey • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com • Own an Upgrade Labs – https://ownanupgradelabs.com • Upgrade Labs – https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement – https://40yearsofzen.com Timestamps: • 00:00 Intro • 00:29 Dave Asprey’s Vision Journey • 04:33 Understanding Vision Beyond 20/20 • 08:01 Impact of Environment on Vision • 22:47 Exercises to Improve Vision • 27:29 Effective Eye Exercises for Better Vision • 27:46 Daily Routine for Eye Health • 29:12 Peripheral Vision Training • 31:15 Vision and Body Connection • 33:38 Handling Visual Overload • 35:04 Vision Training Benefits • 39:25 Neuroplasticity and Vision • 45:22 Vision Training for All Ages • 46:38 Practical Vision Improvement Tips • 54:24 Final Thoughts on Vision Training See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jan 7

What if the secret to living to 250 was simply sitting in the garden? In this episode, Dave sits down with Christian Drapeau, a leading expert in stem cell science, to explore the plants and natural practices that could unlock extreme longevity. From goji berries to reishi mushrooms, these age-old remedies do more than nourish—they activate your body’s innate repair system, boosting stem cells and accelerating healing. Christian dives into the fascinating stories behind these plants, their ancient origins, and how modern science is proving their power to extend life. He also shares how anyone—regardless of age—can tap into these natural tools to transform their health and longevity. Imagine harnessing the same methods as a Chinese healer reportedly living to 250 years old. Could these practices be the missing link to longer, healthier lives? What You’ll Learn: • The surprising plants that naturally stimulate stem cells • How stem cells repair and rejuvenate your body from the inside out • Why fasting can reset your cellular health • Practical tips to harness your body’s natural ability to heal • The secrets to improving recovery, energy, and longevity Resources: • 2025 Biohacking Conference - STEMREGEN is the Title Sponsor – https://biohackingconference.com/2025 • STEMREGEN Website - Visit stemregen.co/dave and save 20% on STEMREGEN! • Christian Drapeau’s Website - https://christiandrapeau.com • Danger Coffee – https://dangercoffee.com • Dave Asprey’s Website – https://daveasprey.com • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books • Dave Asprey’s Linktree – https://linktr.ee/daveasprey • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com • Own an Upgrade Labs – https://ownanupgradelabs.com • Upgrade Labs – https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement – https://40yearsofzen.com Sponsors: Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Puori | Visit https://puori.com/dave and use code DAVE for 20% storewide. Timestamps: • 00:00 Intro • 00:57 Meet Christian Drapeau: Stem Cell Expert • 02:22 Understanding the Innate Repair System • 04:26 Stem Cells and Aging: The Science Explained • 05:27 Fasting and Stem Cell Rejuvenation • 08:34 STEMREGEN: Activating Your Body’s Stem Cells • 12:09 Historical Longevity Practices • 17:59 Enhancing Stem Cell Function: Lifestyle Tips • 22:45 The Role of PEMF in Stem Cell Activation • 26:45 The Importance of Immediate Recovery • 27:22 Stem Cells and Longevity • 28:13 The Bank Account Analogy of Aging • 29:05 Stem Cells and Age-Related Diseases • 30:42 Mind Over Matter: The Brain’s Role in Stem Cell Release • 32:51 The Quantum Mechanics of Stem Cells • 36:22 The Role of Science in Understanding Reality • 42:24 Biological Clocks and Stem Cells • 46:08 Future of Stem Cell Research and Applications • 49:36 Practical Applications and Success Stories • 52:23 Conclusion and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jan 2

Are we protecting our kids—or unknowingly putting their health at risk? Dr. Joel “Gator” Warsh isn’t just another pediatrician; he’s a bold voice speaking out on the vaccine debate that’s dividing parents, doctors, and society. In this episode, we pull back the curtain on one of the most censored and controversial topics of our time. With his integrative and functional approach, Dr. Warsh unpacks the startling rise in chronic illnesses among children and questions if we’re truly asking the hard questions about vaccine safety and efficacy. This isn’t about taking sides—it’s about uncovering the truths every parent needs to know. Dave and Dr. Warsh dive deep into the science, the myths, and the hidden risks Big Pharma doesn’t want you to hear about. Whether you’re a parent, a skeptic, or just someone seeking the truth, this episode will give you the tools and insights to navigate this complex issue with confidence. What You’ll Learn: • The alarming rise in chronic illnesses and what might be driving it • Why vaccine safety studies may not tell the whole story • The critical questions every parent should ask before vaccinating • How toxins in our environment are impacting our kids’ health • Practical steps to protect your children in today’s world Resources: • 2025 Biohacking Conference – https://biohackingconference.com/2025 • Dr. Joel “Gator” Warsh’s Book: Parenting at Your Child’s Pace – https://www.amazon.com/Parenting-Your-Childs-Pace-Pediatricians/dp/1454952490 • Dr. Joel “Gator” Warsh’s Website – https://www.integrativepediatrics.com • Dr. Joel “Gator” Warsh on Instagram – https://www.instagram.com/drjoelgator • Danger Coffee – https://dangercoffee.com • Dave Asprey’s Website – https://daveasprey.com • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books • Dave Asprey’s Linktree – https://linktr.ee/daveasprey • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com • Own an Upgrade Labs – https://ownanupgradelabs.com • Upgrade Labs – https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement – https://40yearsofzen.com Sponsors: -STEMREGEN | Head to https://www.stemregen.co/dave for 20% off your first order. -BON CHARGE | Go to https://boncharge.com/ and use coupon code DAVE to save 15%. Timestamps: • 00:00 Intro • 00:40 Personal Health Journey and Pediatric Concerns • 01:41 Interview with Dr. Joel Gator Warsh • 02:49 Rising Chronic Diseases in Children • 04:03 Factors Contributing to Health Issues • 10:13 Debating Vaccine Safety and Efficacy • 30:32 Historical Context and Vaccine Research • 44:18 Introduction to Dr. Joe Dispenza and Meditation • 45:13 Genetics and Vaccine Controversies • 46:16 The Importance of Individualized Medicine • 49:02 Western Medicine’s Flaws and Alternatives • 50:07 Childhood Health Crisis and Solutions • 50:52 Pharmaceutical Industry Critique • 52:09 The Role of Parents and Doctors in Child Health • 01:04:43 The Influence of Big Pharma on Medicine • 01:19:56 Balancing Vaccination Decisions • 01:25:44 Conclusion and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Dec 31, 2024

Your hearing isn’t just about sound—it’s the key to sharper focus, deeper connections, and increased awareness. In this episode, Dave explores the cutting-edge world of hearing technology with Brandon Sawalich, CEO of Starkey, and reveals how you can gain superhuman hearing with almost no effort. “Listening” to this episode is going to be one of the best things for your hearing. But why? Because your hearing isn’t just about detecting sounds—it’s about transforming the way you experience the world. Imagine real-time translation in 75 languages, tuning out noise pollution, and amplifying what truly matters—all while protecting your brain from cognitive decline and boosting your overall performance. Brandon shares the groundbreaking innovations that redefine what hearing devices can do. From biohacking your auditory environment to integrating AI for mood and health tracking, this conversation will change how you think about your ears, your brain, and your future. What You’ll Gain from This Episode: • Discover how superhuman hearing enhances focus and reduces mental fatigue • Learn why better hearing can slow brain aging and improve mental health • Get an inside look at AI-powered hearing technology that’s changing lives • Understand the surprising connection between hearing and peak performance • Find out how upgrading your hearing can unlock new opportunities for success Sponsor: -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. -ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. Resources: • Starkey Hearing Technologies – Explore AI-powered hearing aids and innovations: https://www.starkey.com • Starkey Blog – Stay updated on the latest in hearing health: https://www.starkey.com/blog • Starkey Instagram - https://www.instagram.com/starkeyhearing/ • Danger Coffee – Clean, mold-free coffee for sustained energy: https://dangercoffee.com • Dave Asprey’s Website – Explore biohacking tools, books, and more: https://daveasprey.com • Dave Asprey’s Book: Smarter Not Harder – Biohacking made simple: https://daveasprey.com/books • Dave Asprey’s Linktree – Access all Dave’s platforms: https://linktr.ee/daveasprey • Upgrade Collective – Join live podcast recordings: https://www.ourupgradecollective.com • Own an Upgrade Labs – Franchise opportunities for cutting-edge health labs: https://ownanupgradelabs.com • Upgrade Labs – The ultimate biohacking experience: https://upgradelabs.com • 40 Years of Zen – Neurofeedback for advanced cognitive enhancement: https://40yearsofzen.com Timestamps: • 00:00 Introduction to Hearing Loss • 01:23 Dave Asprey’s Personal Hearing Journey • 02:47 Guest Introduction: Brandon Sawalich • 03:45 Advancements in Hearing Technology • 06:47 The Importance of Hearing for Brain Health • 17:32 Hearing Aids as Performance Enhancers • 25:32 Future Innovations in Hearing Technology • 27:03 Detecting Lies with Technology • 27:26 The Science of Sleep Enhancement • 29:57 Innovation and Risk-Taking in Business • 32:18 Addressing EMF Concerns with Hearing Aids • 34:26 Ethical Considerations in Technology • 37:06 Empowering Users with AI and Hearing Technology • 43:38 Future of Biohacking and Hearing Superpowers • 44:57 Conclusion and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Dec 26, 2024

Fear is quietly running your life—and it’s holding you back from the purpose and success you deserve. In this episode, we revisit Dave chatting with one of the keynote speakers for the Biohacking Conference 2025, Ryan Holiday, the bestselling author of Courage Is Calling , to tackle the one thing standing between you and your potential: fear. Why should you listen? Because fear is the root cause of procrastination, self-doubt, and the endless excuses that keep you stuck. Ryan reveals why courage isn’t just about bravery—it’s about making the hard choices that align with your purpose, even when the stakes are high. Drawing on powerful examples from history and modern life, Ryan explains how fear can be transformed into a catalyst for action and why embracing discomfort is the key to unlocking true freedom. If you’ve ever felt paralyzed by uncertainty, this episode will give you the tools and perspective to take control, face your fears, and create the life you’re meant to live. Why This Episode Matters: • You’ll discover how fear sneaks into your decisions—and how to stop it • Learn why courage is the ultimate skill for success and fulfillment • Get actionable advice to break through self-imposed limits • Understand the psychology of fear and how to use it as fuel • Hear real-life stories of people who overcame fear to achieve greatness Resources: 2025 Biohacking Conference – https://biohackingconference.com/2025 Ryan Holiday’s Website – https://ryanholiday.net Daily Stoic Website – https://dailystoic.com/ Ryan Holiday’s Book: Courage Is Calling – https://a.co/d/czEfCXC Ryan Holiday’s Instagram – https://www.instagram.com/ryanholiday Danger Coffee – https://dangercoffee.com Dave Asprey’s Website – https://daveasprey.com Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books Dave Asprey’s Linktree – https://linktr.ee/daveasprey Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com Own an Upgrade Labs – https://ownanupgradelabs.com Upgrade Labs – https://upgradelabs.com 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement – https://40yearsofzen.com Sponsors -Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. -Pendulum | Go to https://pendulumlife.com/ and use code Asprey20 for your first month of GLP-1 or any Pendulum formula. Timestamps: • 00:00 – Intro • 00:44 – Discussing Ryan Holiday’s Work • 02:37 – The Concept of Courage • 08:09 – Fear and Courage in History • 12:41 – Stoic Philosophy and Modern Applications • 21:50 – The Four Virtues and Their Interrelation • 28:39 – Challenges in Admitting Mistakes • 35:21 – Navigating Business Risks During a Pandemic • 36:44 – The Essence of Courage in Business and Life • 37:03 – Reed Hastings and the Duality of Courage • 40:06 – Moral Courage: Lessons from History • 43:35 – The Debate on Mandates and Personal Freedom • 45:22 – Balancing Public Health and Individual Rights • 58:29 – The Role of Responsibility in Society • 01:09:01 – The Importance of Intellectual Courage • 01:12:04 – Reaching Audiences in a Noisy World • 01:13:27 – Final Thoughts and Encouragement See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Dec 24, 2024

Today we are bringing back one of our all-time favorite episodes with James Altucher. Dave sits down with James, an entrepreneur, bestselling author, and master experimenter, to uncover why the 10,000-hour rule might just be holding you back. Instead of grinding your way to expertise, James reveals his 10,000 Experiment Rule—a game-changing approach to mastering any skill faster than you thought possible. From comedy stages to boardrooms, James has redefined success through relentless experimentation and bold pivots. In this electrifying conversation, he exposes the toxic allure of “failure porn” and why glorifying failure might be sabotaging your growth. You’ll learn why skipping the line isn’t just possible—it’s essential for thriving in a world obsessed with rigid rules. This episode dives deep into the power of curiosity, the art of experimentation, and the strategies James uses to crush the myth of conventional wisdom. Whether you’re stuck in a career rut, looking to start something new, or just want to optimize your life, James delivers unfiltered insights to help you rewrite the rules. What You’ll Learn: • Why the 10,000-hour rule is outdated—and what actually works • How “failure porn” is dragging you down (and how to escape it) • The 10,000 Experiment Rule that accelerates skill mastery • Bold strategies to break through limits and skip the line in any industry • Why curiosity is the ultimate superpower for growth and success • Practical steps to monetize your passion and build a life you love Resources: 2025 Biohacking Conference – https://biohackingconference.com/2025 James Altucher’s Website – https://www.jamesaltucher.com The James Altucher Show Podcast – https://podcasts.apple.com/us/podcast/the-james-altucher-show/id794030859 Danger Coffee – https://dangercoffee.com Dave Asprey’s Website – https://daveasprey.com Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books Dave Asprey’s Linktree – https://linktr.ee/daveasprey Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com Own an Upgrade Labs – https://ownanupgradelabs.com Upgrade Labs – https://upgradelabs.com 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement – https://40yearsofzen.com Sponsors -Calroy | Head to https://calroy.com/dave for an exclusive discount. -Viome | Go to https://viome.com/dave to save $110 on the Full Body Intelligence Test. Timestamps: 00:00 Introduction to The Human Upgrade Podcast 00:38 Meet James Altucher: Entrepreneur and Author 01:02 The Comedy Journey: From Advice to Stage 02:06 The Controversial New York Article 03:42 Facing Backlash and Public Reaction 10:46 The 10,000 Experiment Rule 15:44 Skipping the Line: Challenging Conventional Wisdom 23:35 The Importance of Loving What You Do 31:30 A Chance Encounter with Howard Schultz 32:11 The Plus Minus Equals Technique 33:26 Applying Techniques to Chess Mastery 34:43 The Importance of Curiosity 36:30 Experimenting with Comedy 38:44 The Concept of Failure Porn 40:39 The Hero’s Journey in Business 44:42 Living an Experimental Life 47:10 Frame Control in High-Stakes Situations 53:43 Advice for Parents and Kids 55:29 Conclusion and Book Promotion See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Dec 19, 2024

Can you use hate to make the world a better place? Daryl Davis, a world-class jazz musician, didn’t just confront hate—he dismantled it. By sitting down with over 200 Ku Klux Klan members, he inspired them to leave their robes behind. But this isn’t just a story about racism or redemption; it’s a story about the incredible power of human connection and the lessons it holds for all of us. In this special episode, Dave explores how Daryl turned impossible conversations into transformative breakthroughs. Together, they unpack the mindset shifts, emotional intelligence, and fearless curiosity that can break down barriers of all kinds—whether they’re rooted in bias, fear, or misunderstanding. Daryl’s approach to erasing hate is so unique, so impactful, that it may just change how you view conflict, compassion, and even your own health. What You’ll Learn: • How Daryl’s global upbringing shaped his fearless approach to conflict • Why eliminating hate starts with understanding, not opposition • The neuroscience of compassion and how it rewires your brain • How forgiveness can transform your health and happiness • A step-by-step framework for tackling impossible conversations Resources: 2025 Biohacking Conference – https://biohackingconference.com/2025 Daryl Davis's Book: Klan-destine Relationships (Go read it for free at your local library instead of buying on Amazon :)) Daryl Davis's Website – https://www.daryldavis.com Daryl Davis on Instagram – https://www.instagram.com/realdaryldavis/ Danger Coffee – https://dangercoffee.com Dave Asprey’s Website – https://daveasprey.com Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books Dave Asprey’s Linktree – https://linktr.ee/daveasprey Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com Own an Upgrade Labs – https://ownanupgradelabs.com Upgrade Labs – https://upgradelabs.com 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement – https://40yearsofzen.com Sponsors: -Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Timestamps: • 00:00 A Shocking Parade Experience • 00:38 Meeting the KKK: First Impressions • 01:06 Introducing Daryl Davis • 03:46 Daryl’s Unique Upbringing • 09:52 Confronting Racism: A Lifelong Quest • 14:16 The Power of Travel and Perspective • 18:25 A High School Encounter with Nazis • 21:12 Confronting the Klan Leader • 30:57 Changing Minds: A Personal Approach • 36:30 The Illusion of Latent Genes • 42:08 Collecting Klan Robes: A Symbolic Victory • 46:17 Facing the Klan: Staying Grounded • 48:27 Challenging Beliefs: Confronting Hate • 49:15 The Journey to Writing ‘Clandestine’ • 50:26 Introducing ‘The Klan Whisperer’ • 51:35 Reflections on Racism and History • 57:29 The Power of Forgiveness • 59:28 Freedom of Speech and Its Limits • 01:02:21 Personal Stories of Racism • 01:13:16 Cultural Understanding and Misunderstandings • 01:25:16 The Impact of Music on Memory • 01:29:02 Final Thoughts and Upcoming Events See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Dec 17, 2024

Is AI About to Replace Your Doctor? Or Save Your Life? The tools that are reshaping healthcare will redefine medicine—and your life—in ways you’ve never imagined. Will artificial intelligence and regenerative therapies like stem cells and exosomes make doctors obsolete? Or will they finally unlock the secrets to living to 180? In this episode, Dave sits down with Dr. Pradeep Albert, a leader in regenerative medicine and AI-driven imaging, to explore the intersection of technology, longevity, and healing. Dr. Albert shares groundbreaking insights on how AI is revolutionizing medical diagnostics, replacing outdated systems, and empowering patients to take control of THEIR OWN health. He also dives deep into regenerative therapies—how PRP, exosomes, and stem cells are changing the game for injuries, inflammation, and aging. Can AI improve patient-doctor relationships? Are doctors becoming coaches instead of gatekeepers? And most importantly, how can you leverage these tools to outlive your peers and enhance every aspect of your health? What You’ll Learn: • Why 50% of people won’t make it past 76—and how to beat the odds • How AI is already better than doctors at diagnosing certain conditions • The truth about PRP, exosomes, and stem cells—and when to use each • The three rules of longevity every person needs to know • How your mindset and epigenetics can help you live longer and healthier Resources: 2025 Biohacking Conference – https://biohackingconference.com/2025 Dr. Pradeep Albert’s Book: Exosomes, PRP, and Stem Cells…Medicine – https://www.amazon.com/Exosomes-Stem-Cells-Musculoskeletal-Medicine/dp/B0C2S59S8K Dr. Pradeep Albert’s Book: Lifespan Decoded – https://lifespandecoded.com/ Dr Pradeep Albert’s Website – https://drpradeepalbert.com/ Danger Coffee – https://dangercoffee.com Dave Asprey’s Website – https://daveasprey.com Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books Dave Asprey’s Linktree – https://linktr.ee/daveasprey Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com Own an Upgrade Labs – https://ownanupgradelabs.com Upgrade Labs – https://upgradelabs.com 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement – https://40yearsofzen.com Sponsors: ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. OneSkin | Go to https://oneskin.co/ and use code ASPREY15 for 15% off your purchase. Timestamps: • 00:00 – Introduction to AI in Medicine • 00:36 – The Role of AI in Longevity • 00:51 – Meet Dr. Pradeep Alpert • 01:11 – AI’s Impact on Healthcare • 02:07 – Changing Role of Doctors • 05:01 – AI in Medical Imaging • 06:37 – Orthopedics and AI • 09:19 – Longevity and Epigenetics • 14:16 – The Importance of Mindset • 29:08 – Trust in the Medical System • 43:18 – DIY Health and Longevity • 44:21 – The Future of Insurance and Medical Costs • 45:45 – Advancements in Imaging Technology • 47:26 – The Art of Physical Examination • 50:21 – Regenerative Medicine: PRP, Exosomes, and Stem Cells • 01:00:23 – Challenges in the US Medical System • 01:07:54 – The Role of AI in Medicine • 01:18:14 – Final Thoughts and Book Promotion See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Dec 13, 2024

Most people don’t think about their liver until it’s too late. In this episode, Dave sits down with Siggi Clavien, founder of de-liver-ance® & The Liver Clinic, to uncover the hidden superpowers of the body’s most underrated organ: the liver. This is a deep dive into why your liver is the ultimate game-changer for your energy, brain power, and longevity. Siggi reveals groundbreaking insights on reversing fatty liver disease, boosting detoxification, and harnessing the liver’s regenerative capabilities. From fighting brain fog to protecting against toxins, this episode will have you rethinking everything about how you treat your body. And yes, your liver could be the key to living a healthier, happier life. Siggi also shares the science and innovation behind de-liver-ance®, his groundbreaking herbal product designed to deliver the most powerful results in a safe, natural way. Backed by millions of dollars and years of research, de-liver-ance® is setting a new standard in liver health. Use code: DAVE at https://us.loveyourliver.com/discount/DAVE to get a discount! Dave and Siggi also explore cutting-edge strategies to supercharge your liver health using natural herbs, breakthrough science, and biohacking tools. What You’ll Learn: • Why your liver holds the key to longevity, energy, and mental clarity • How to reverse fatty liver disease—even if you’ve been told it’s irreversible • The truth about common liver-destroying habits you need to ditch now • Groundbreaking ways to protect and regenerate your liver for optimal health • The science behind de-liver-ance® and how it’s changing liver health forever • Simple, actionable strategies to boost detoxification and supercharge your body Resources: 2025 Biohacking Conference – https://biohackingconference.com/2025 de-liver-ance® – https://us.loveyourliver.com/discount/DAVE (Use code DAVE at checkout for a discount!) The Liver Clinic – https://theliverclinic.com Danger Coffee – https://dangercoffee.com Dave Asprey’s Website – https://daveasprey.com Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books Dave Asprey’s Linktree – https://linktr.ee/daveasprey Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com Own an Upgrade Labs – https://ownanupgradelabs.com Upgrade Labs – https://upgradelabs.com 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement – https://40yearsofzen.com Timestamps: • 00:00 Intro • 00:00 Introduction and Liver Basics • 01:46 Guest Introduction and Liver Health Insights • 02:16 Understanding Liver Scans and Lab Panels • 05:13 Fatty Liver Disease: Causes and Consequences • 07:07 Diet and Liver Health • 09:47 Supplements and Liver Function • 11:53 Advanced Liver Health Strategies • 14:05 Biohacking and Liver Health • 17:41 Deliverance Supplement and Its Benefits • 23:12 Liver Health and Longevity • 31:12 Biohacking: The Path to Consciousness and Longevity • 32:29 The Liver: The Body’s Regenerative Powerhouse • 34:48 Gut Microbiome and Liver Health Connection • 35:59 Lipopolysaccharides: The Hidden Toxins • 40:44 Coffee: A Surprising Ally for Liver Health • 43:16 Mold Toxins: The Silent Liver Destroyers • 48:43 Hormone Health and the Liver • 52:19 Type 2 Diabetes, Menopause, and Liver Health • 52:43 The Impact of Lifestyle on Liver Health • 54:57 The Importance of Bile and Gallbladder Health • 58:06 Genetics, Toxins, and Liver Resilience • 01:06:25 Conclusion: Investing in Liver Health for a Better Life See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Dec 12, 2024

Will the next nuclear bomb be AI Superintelligence? The intelligence we’re building will reshape the world in ways we never imagined—for better or worse? But more importantly, what side will humanity take? In this episode, Mo Gawdat, bestselling author of Scary Smart and former Chief Business Officer of Google X, joins Dave to tackle the profound challenges and opportunities artificial intelligence presents. This isn’t about dystopian robots or tech hype—it’s about redefining what it means to be human in the age of machines. There’s hope, don’t worry! Mo dives into the reality of how AI is already shaping our behavior, our ethics, and even our potential for happiness. He reveals the critical need for aligning intelligence—human or artificial—with values that promote global abundance and collaboration. Dave and Mo mix data, philosophy, and bold visions, to show why our future depends on shifting from competition to cooperation. But most importantly, why all of this is going to make you a better YOU. What You’ll Learn: • The real reason AI is reshaping human behavior—and how to take back control • Why intelligence without ethics could lead to catastrophe • How abundance thinking can unlock limitless possibilities for humanity • The crucial mindset shifts leaders need to adopt before it’s too late • Practical insights for ensuring AI supports human flourishing, not destruction Resources: 2025 Biohacking Conference – https://biohackingconference.com/2025 Mo Gawdat’s Book: Scary Smart – https://a.co/d/6DukqyW Mo Gawdat’s Book: Unstressable – https://a.co/d/hrbpY9O Follow Mo Gawdat on Instagram – https://www.instagram.com/mo_gawdat/ Danger Coffee – https://dangercoffee.com Dave Asprey’s Website – https://daveasprey.com Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books Dave Asprey’s Linktree – https://linktr.ee/daveasprey Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com Own an Upgrade Labs – https://ownanupgradelabs.com Upgrade Labs – https://upgradelabs.com 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement – https://40yearsofzen.com Sponsors: - Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. - fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Timestamps: • 00:00 The Ethical Dilemma of AI in Warfare • 00:31 Introduction to Part Two with Mo Gawdat • 00:58 AI and Human Happiness: A Complex Relationship • 03:18 The Power and Responsibility of Technology • 05:08 The Rise of AI and Its Impact on Society • 08:31 The Future of AI: Abundance or Destruction? • 19:53 The Role of Ethics in AI Development • 22:39 Conclusion and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Dec 10, 2024

Can Happiness Really Be Engineered? Mo Gawdat Says Yes—And Here’s How. I know what you’re thinking… ANOTHER episode on happiness? Haven’t we heard it all before? This one’s different. The code is cracked, and you’re about to learn exactly how it works. Joining us today is Mo Gawdat, bestselling author of Unstressable and former Chief Business Officer of Google X. Mo sits down with Dave to deliver a practical, science-backed approach to hacking your mind and body for lasting joy. Mo dives into the raw science behind happiness and stress—revealing how your brain runs on algorithms that you can actually reprogram. Discover why dopamine might be sabotaging your joy, how to decode the four types of stress, and biohacks that can flip the script on your mental and physical resilience. He also shares the deeply personal story of how he turned unimaginable tragedy into a global mission for happiness and purpose. Mo’s insights will challenge everything you thought you knew about living a fulfilled life. What You’ll Learn: • The happiness algorithm—and how to make it work for you • Why dopamine addiction is robbing you of joy (and how to fix it) • The four stress modalities and how to regain control • Biohacks that build resilience—like cold plunges, gratitude, and micro-habits • How small mindset shifts can create major life transformations And don’t miss Part 2, dropping in two days! Dave and Mo explore the intersection of happiness and AI, revealing how to get them both working FOR you instead of against you. Resources: 2025 Biohacking Conference – https://biohackingconference.com/2025 Mo Gawdat’s Book: Scary Smart – https://a.co/d/6DukqyW Mo Gawdat’s Book: Unstressable – https://a.co/d/hrbpY9O Follow Mo Gawdat on Instagram – https://www.instagram.com/mo_gawdat/ Danger Coffee – https://dangercoffee.com Dave Asprey’s Website – https://daveasprey.com Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books Dave Asprey’s Linktree – https://linktr.ee/daveasprey Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com Own an Upgrade Labs – https://ownanupgradelabs.com Upgrade Labs – https://upgradelabs.com 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement – https://40yearsofzen.com Sponsors: Neurohacker | Go to https://qualialife.com/dave and use code Dave for 15% off. Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. Timestamps: 00:00 – Intro 00:31 – Introduction to The Human Upgrade 00:45 – Dave Asprey’s AI Background 01:13 – Introducing Mo Gawdat and His Work 01:51 – From Scary Smart to Unstressable 02:40 – The Journey to Happiness 13:10 – Understanding Stress and Its Mechanisms 17:26 – The Four Modalities of Stress 24:16 – Mental Stress and the Happiness Flowchart 31:34 – Sources of Stress: Trauma, Obsessions, Noise, and Nuisances 33:27 – Understanding Modern PTSD 34:09 – The Role of Obsessions and Noise 36:24 – Biohacking for Resilience 37:58 – The Power of Gratitude 40:12 – The Happiness Equation 54:37 – Dopamine vs. Serotonin 01:03:00 – The Benefits of Cold Therapy See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Dec 5, 2024

Does Calorie Restriction Even Work? What About the Carnivore Diet AND Fruit? Today we are excited to have Paul Saladino join us for a masterclass on food and diets. Dr. Saladino dives into the evolution of keto and carnivore diets, cutting through trends to focus on lasting health impacts. Dr. Saladino, widely recognized as CarnivoreMD, shares how his own diet shifted to include fruit and honey alongside animal-based nutrition, and why metabolic flexibility—not rigid rules—leads to better outcomes. Together, he and Dave challenge assumptions about long-term ketosis, examine its potential downsides, and explore how to optimize diets for energy, gut health, and longevity. They also tackle controversial topics like the risks of seed oils, the overhyped reputation of “health foods” like quinoa, and the critical roles insulin and nutrient density play in overall wellness. With insights on balancing mTOR, managing omega fats, and incorporating organ meats, this episode offers a nuanced perspective for anyone interested in biohacking, nutrition science, or simply eating smarter. What you’ll learn: • Why metabolic flexibility matters more than strict diet rules • The science behind long-term ketosis and insulin’s broader role in health • How common “health foods” could be doing more harm than good • The importance of nutrient-dense animal-based foods for gut and immune health • How to achieve optimal balance between fat types, mTOR, and longevity markers Resources: 2025 Biohacking Conference – https://biohackingconference.com/2025 Shop Paul Saladino’s Products – https://heartandsoil.co Follow Paul Saladino on Instagram – https://www.instagram.com/paulsaladinomd/ Paul Saladino’s Book: The Carnivore Code – https://www.amazon.com/Carnivore-Code-Unlocking-Returning-Ancestral/dp/035846997X Lineage Provisions – 100% Grass-Fed Beef Tallow – https://lineageprovisions.com/products/100-grass-fed-beef-tallow Danger Coffee – https://dangercoffee.com Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ Dave Asprey’s Website – https://daveasprey.com Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books Dave Asprey’s Linktree – https://linktr.ee/daveasprey Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com Own an Upgrade Labs – https://ownanupgradelabs.com Upgrade Labs – https://upgradelabs.com 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement – https://40yearsofzen.com Sponsors: - Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. - LMNT | Free LMNT Sample Pack with any drink mix purchase by going to https://drinklmnt.com/dave . Timestamps: • 00:00 Intro • 00:40 Paul Saladino’s Evolution in Diet • 01:21 Challenges of a Strict Carnivore Diet • 03:36 Reintroducing Carbohydrates • 05:32 Debunking Common Diet Myths • 13:49 The Problem with Calorie Restriction • 18:30 The Importance of Food Quality • 24:08 The Veganism Debate • 34:15 The Benefits of Organ Meats • 37:27 Foot Surgery and Bone Density • 39:23 Mineral Deficiency and Plant-Based Diets • 40:00 The Truth About Seed Oils • 41:10 Historical Studies on Seed Oils • 47:26 Mechanisms and Effects of Seed Oils • 52:33 Nicotine and Neuroprotection • 54:12 Oleic Acid and Longevity • 01:01:44 The Benefits of Animal Fats • 01:02:32 Odd Chain Fatty Acids and Health • 01:11:07 Cheese and Dairy Considerations • 01:13:11 The Impact of Cheese on Health • 01:14:03 Protein Intake and Longevity • 01:14:54 Understanding mTOR and Its Effects • 01:17:35 Ideal Body Fat and Metabolic Health • 01:24:38 The Role of Omega Fatty Acids • 01:32:46 ApoB, Insulin Sensitivity, and Longevity • 01:43:09 Final Thoughts and Product Recommendations See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Dec 3, 2024

What are the oral hygiene tips that could save your life? Dave Asprey sits down with one of the most popular guests on the show, Naveen Jain, founder and CEO of Viome Life Sciences, to explore how your oral microbiome influences not just your dental health but your entire body. Naveen reveals groundbreaking insights into how imbalances in oral bacteria can trigger chronic inflammation, heart disease, and even cancer—and how understanding your unique microbiome can help prevent these risks. Discover why oral health goes far beyond brushing and flossing, how to optimize your oral microbiome for longevity, and why common mouthwashes may be doing more harm than good. Naveen also introduces cutting-edge solutions from Viome, including personalized oral lozenges and postbiotics, to elevate both your oral and overall health. In this episode, you’ll also uncover the exact foods to eat and avoid to live a longer, healthier, and more vibrant life. What you’ll learn in this episode: • The surprising link between your oral microbiome and chronic disease • Why bacterial diversity in your mouth is essential for overall health • How leaky gums drive systemic inflammation and increase health risks • The dangers of over-sterilizing your mouth and eliminating beneficial bacteria • Personalized solutions to improve oral and gut health with Viome • Actionable tips to optimize your oral microbiome for better longevity Resources: • 2025 Biohacking Conference – https://biohackingconference.com/2025 • Viome Full Body Intelligence Test (Save $110) – https://www.viome.com/dave • Viome Instagram – https://www.instagram.com/viome • Learn More About Viome – https://viome.com • Danger Coffee – https://dangercoffee.com • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ • Dave Asprey’s Website – https://daveasprey.com • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books • Dave Asprey’s Linktree – https://linktr.ee/daveasprey • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com • Own an Upgrade Labs – https://ownanupgradelabs.com • Upgrade Labs – https://upgradelabs.com • 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com Sponsors: -Leela Quantum | Head to https://leelaq.com/DAVE for 10% off. -ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. Timestamps: • 00:00 Introduction to Viome and Its Impact on Health • 00:53 Meet Naveen Jain: Visionary Behind Viome • 02:41 Understanding the Microbiome and Its Role in Health • 05:54 The Power of RNA Analysis in Personalized Health • 12:19 Diet, Microbiome, and Personalized Nutrition • 29:50 The Importance of Oral and Gut Health • 39:20 Debating the Benefits of Intermittent Fasting • 40:08 The Role of Gut Bacteria in Fasting and Diet • 42:12 Understanding Chronic Inflammation and Diet • 44:13 The Keto Diet Myths and Realities • 45:44 Oxalates and Superfoods What You Need to Know • 49:25 The Concept of Holobiont and Human Health • 56:21 The Five Pillars of Longevity • 01:02:04 The Importance of Quality Sleep • 01:05:18 Purpose and Community for a Longer Life • 01:09:48 Upcoming Topics and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 28, 2024

Is this the missing link in fertility? The vaginal microbiome could be the most overlooked factor in optimizing women’s health, from fertility and hormonal balance to preventing infections and improving quality of life. In this groundbreaking episode, Dave Asprey talks to Priyanka Jain, co-founder and CEO of Evvy, about how understanding and improving the vaginal microbiome can transform women’s health outcomes. Priyanka shares how Evvy is advancing women’s health through cutting-edge genomic research and AI-powered insights, offering solutions to challenges like bacterial vaginosis, yeast infections, recurrent UTIs, and even infertility. You’ll learn why this critical microbiome plays such a vital role, how hormonal changes and lifestyle impact it, and how personalized approaches can improve reproductive and overall health. This episode explores not just women’s health but also how understanding the vaginal microbiome can influence relationships, biohacking, and even groundbreaking fertility research. Don’t miss this deep dive into the science and solutions shaping the future of health. Here’s what you’ll learn in this episode: • The critical role the vaginal microbiome plays in women’s health and fertility • How hormonal changes affect vaginal health and microbiome balance • The link between vaginal microbiome imbalances and conditions like bacterial vaginosis, yeast infections, and UTIs • Evvy’s innovative approach to using AI and genomics for personalized health insights • Practical tips for maintaining microbiome health, including probiotics, hydration, and hormone balance • The connection between the vaginal microbiome and overall quality of life Resources: • 2025 Biohacking Conference – https://biohackingconference.com/2025 • Shop at Evvy (Use coupon code DAVE for $10 off!) – https://shareasale.com/r.cfm?b=1862577&u=2810239&m=116251&urllink=&afftrack= • Follow Evvy on Instagram – https://www.instagram.com/evvy • Danger Coffee – https://dangercoffee.com • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ • Dave Asprey’s Website – https://daveasprey.com • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books • Dave Asprey’s Linktree – https://linktr.ee/daveasprey • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com • Own an Upgrade Labs – https://ownanupgradelabs.com • Upgrade Labs – https://upgradelabs.com • 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com Sponsors: - Calroy | Head to https://calroy.com/dave for an exclusive discount. Timestamps: • 00:00 Trailer • 00:35 Introduction to Vaginal Microbiome • 01:12 Meet Priyanka Jain of Evvy • 02:03 Understanding the Vaginal Microbiome • 04:37 Challenges in Women’s Health • 09:55 Impact of Lifestyle on Vaginal Health • 11:22 The Role of Diet and Supplements • 15:24 Sexual Health and Vaginal Microbiome • 27:25 Menopause and Vaginal Health • 31:23 Optimizing Vaginal Health • 39:31 Exploring Women’s Health Data • 41:17 The Role of Vaginal Microbiome in Fertility • 43:44 Affordable Testing and Discount Offers • 45:31 The Impact of Lubricants on Vaginal Health • 46:20 Innovative Ideas for Probiotic Products • 47:29 Audience Questions and Precision Medicine • 48:04 The Importance of Data in Women’s Health • 54:31 Marketing and Misinformation in Vaginal Health • 01:06:34 The Connection Between Diet and Vaginal Health • 01:12:49 Conclusion and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 26, 2024

Is alcohol losing its grip as the go-to social drink? Enter kava—a centuries-old Polynesian plant that’s gaining global recognition for its ability to relax the mind, elevate mood, and enhance social connection without the toxic effects of alcohol. Kava, particularly in the form of TRU KAVA, is a psychoactive yet non-intoxicating drink that offers the perfect balance of calm focus and mental clarity. In this episode, Dave Asprey welcomes Cameron George, founder of TRU KAVA, to discuss why kava is becoming the drink of choice for those seeking a healthier, more connected lifestyle. Learn how kava impacts neurotransmitters like GABA and dopamine, enhances creativity and emotional grounding, and even helps the body recover from stress and trauma. Discover why kava is taking center stage in the biohacking and sober-curious movements as a new tool for wellness and connection. Here’s what you’ll learn in this episode: • Why 41% of Americans and 61% of Gen Z are drinking less alcohol • What kava is, how it works, and its history as a ceremonial and social beverage • The science behind kava’s calming and neuroprotective effects • How kava supports creativity, emotional resilience, and authentic social connection • Practical uses for kava, including stress relief, sleep enhancement, and travel recovery Resources: • 2025 Biohacking Conference – https://biohackingconference.com/2025 • TRU KAVA – https://www.trukava.com • TRU KAVA Instagram – https://www.instagram.com/trukava • Danger Coffee – https://dangercoffee.com • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ • Dave Asprey’s Website – https://daveasprey.com • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books • Dave Asprey’s Linktree – https://linktr.ee/daveasprey • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com • Own an Upgrade Labs – https://ownanupgradelabs.com • Upgrade Labs – https://upgradelabs.com • 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com Sponsors: -Quantum Upgrade |Go to https://quantumupgrade.io/Dave for a free trial. -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Timestamps: • 00:00 Intro • 00:37 Introduction to Alcohol Trends • 01:57 Meet Cameron George and TRU KAVA • 02:29 What is Kava? • 05:03 Kava’s Effects on the Brain • 06:53 Kava vs. Alcohol • 08:54 Active Compounds in Kava • 10:10 Kava’s Safety and Standardization • 16:17 Kava in Social Settings • 21:28 Kava and Psychedelics • 31:26 Kava for Public Speaking and Anxiety • 34:04 Kava in the Workplace: Enhancing Team Creativity • 35:22 Kava and Libido: The Unexpected Benefits • 36:06 Biohacking with Kava: Energy Allocation and Community • 39:00 Kava’s Role in Meditation and Emotional Awareness • 42:04 Kava During Pregnancy: Safety and Traditions • 44:37 Kava’s Neuroprotective Properties: A Deep Dive • 45:49 Kava and EMF Sensitivity: A Surprising Connection • 48:39 Kava for Frequent Travelers: Enhancing Mitochondrial Health • 52:46 Kava and Metabolic Health: Fasting and Fat Burning • 57:14 Kava Products: Oils, Beverages, and Their Uses • 01:01:27 The Future of Kava: Social Impact and Cultural Integration • 01:05:28 Conclusion: The Potential of Kava in Modern Society See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 22, 2024

Have we finally discovered the key to youthful energy, longevity, and cellular health? In this episode, Dave Asprey sits down with Dr. Anurag Singh, Chief Medical Officer at Timeline Nutrition and a leading expert on mitochondrial health, cellular regeneration, and anti-aging science. With over 20 years of research, 50 clinical trials, and 15 patents under his belt, Dr. Singh unpacks the groundbreaking science behind Urolithin A, a revolutionary postbiotic that boosts mitochondrial function, enhances immune system resilience, and combats chronic inflammation. This episode goes beyond cutting-edge science. Dr. Singh reveals practical, real-world strategies to combat “inflammaging”—the chronic, low-grade inflammation that accelerates aging. Learn how fasting, gut health, and mitochondrial boosters like Urolithin A can rejuvenate your cells, fight fatigue, and supercharge your energy, vitality, and longevity. Here’s what you’ll learn in this episode: • What Urolithin A is and its role in mitochondrial health and cellular energy production • How to reverse “inflammaging” and reduce inflammation through nutrition, fasting, and biohacking • The connection between mitochondrial dysfunction and immune system aging • Real-life benefits of Urolithin A for energy levels, athletic recovery, skin health, and longevity • Why mitochondrial support is critical for combating aging and improving overall performance Resources: • 2025 Biohacking Conference – https://biohackingconference.com/2025 • Timeline Nutrition - https://www.timeline.com/dave to get 10% off your first order • Timeline Instagram – https://www.instagram.com/timeline_longevity/ • Dave Asprey’s Website – https://daveasprey.com • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books • Danger Coffee – https://dangercoffee.com • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ • Dave Asprey’s Linktree – https://linktr.ee/daveasprey • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com • Own an Upgrade Labs – https://ownanupgradelabs.com • Upgrade Labs – https://upgradelabs.com • 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com Timestamps: • 00:00 Introduction to Longevity and Mitochondria • 01:28 The Role of Mitochondria in Immune Health • 03:36 Understanding Inflammaging and Immune Aging • 07:47 Measuring Immune Health and Inflammation • 13:33 Urolithin A: A Mitochondrial Booster • 16:46 Dosage and Effects of Urolithin A • 26:11 Urolithin A and Exercise Performance • 28:31 Urolithin A for Skin Health • 31:34 Collagen and Aging: The Role of MMPs • 33:27 Personal Experience with MMPs and Recovery • 35:04 Measuring MMPs and Their Impact on Longevity • 36:18 Skin Health and Urolithin A • 38:39 Exploring Urolithin A’s Broader Benefits • 40:33 Brain Health and Urolithin A • 43:33 Combining Supplements for Optimal Health • 45:54 Omega-3s and Mitochondrial Health • 46:51 Ketones, MCTs, and Urolithin A • 54:30 Final Thoughts on MitoPure and Supplementation See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 21, 2024

Are exosomes the planet’s ultimate healing tool?! In this episode, Dave Asprey sits down with Harvard-trained physician Dr. Edward Park to explore the groundbreaking science of exosomes. Dr. Park, a pioneer in regenerative medicine and author of Exosomes: Songs of Healing , explains how these tiny cellular messengers are revolutionizing health and longevity by bypassing the limitations of stem cells. BUT this episode isn’t just about cutting-edge science. Dr. Park also shares profound insights into life, resilience, and emotional well-being, offering advice that goes far beyond medicine. From the power of forgiveness to breaking free of limiting beliefs, his perspective blends science, spirituality, and practical wisdom for living a better life. Here’s what you’ll learn in this episode: • How exosomes work and why they’re being called the future of regenerative medicine • The key differences between exosomes and stem cells—and which is better for healing • Real-life applications of exosome therapy for injuries, anti-aging, and overall health • The potential of exosomes to enhance brain function, reduce inflammation, and promote recovery • Dr. Park’s advice on emotional resilience, gratitude, and creating lasting change With over a decade of experience, Dr. Park shares compelling case studies, cutting-edge insights, and practical advice for anyone looking to upgrade their body, mind, and life. Whether you’re managing chronic pain, exploring anti-aging therapies, or seeking wisdom for navigating life’s challenges, this episode has something for everyone. Sponsors TRU KAVA | Go to https://trukava.com and enter code DAVE15 at checkout for 15% off Resources: • 2025 Biohacking Conference – https://biohackingconference.com/2025 • Dr. Edward Park’s Website: Recharge Biomedical – https://www.rechargebiomedical.com • Dr. Edward Park’s Book: Exosomes: Songs of Healing – https://www.amazon.com/EXOSOMES-Songs-Healing-Ed-Park/dp/098260632X • Dr. Edward Park’s YouTube Channel – https://www.youtube.com/channel/UCpp9DlRArB1rKAWNwoouiTg • Dr. Edward Park on Instagram – https://www.instagram.com/dredpark/ • Dave Asprey’s Website – https://daveasprey.com • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books • Danger Coffee – https://dangercoffee.com • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ • Dave Asprey’s Linktree – https://linktr.ee/daveasprey • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com • Own an Upgrade Labs – https://ownanupgradelabs.com • Upgrade Labs – https://upgradelabs.com • 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com Timestamps: • 00:00 Introduction to Exosomes and Healing • 00:48 Understanding Exosomes: Stem Cell Communication • 01:19 Dr. Edward Park’s Insights on Exosomes • 02:47 Exosomes vs. Traditional Treatments • 04:44 Exosomes in Regenerative Medicine • 07:33 Cost-Effective Regeneration Protocols • 12:35 Exosomes for Hair Growth • 14:37 Stem Cells and Brain Health • 25:33 Banking Stem Cells for Future Use • 35:27 Epigenetic Age and Longevity Predictors • 37:48 CRISPR and Gene Editing: Risks and Benefits • 39:43 Basic Health Tips for Longevity • 41:02 Spirituality, Past Lives, and Healing • 42:50 Questioning Medical and Political Narratives • 47:54 The Importance of Free Speech • 01:07:40 The Role of Intuition in Medicine • 01:09:22 Conclusion and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 19, 2024

Is biohacking your sweat the secret to vitality? Dave Asprey dives into the transformative world of infrared saunas with Connie Zack, founder of Sunlighten and a 25-year innovator in the space. Together, they uncover how targeted light and heat therapy can unlock unparalleled health benefits, from detoxing heavy metals to energizing your body at the cellular level. Here’s what you’ll learn in this episode: • Why infrared saunas excel at detoxing heavy metals and toxins • How they mimic exercise to boost cardiovascular health and recovery • The science behind infrared’s impact on mitochondrial energy and longevity • Surprising benefits for gut health, inflammation, and hormone balance • Hacks to get the most out of your infrared sauna sessions Connie shares cutting-edge research and personal insights, offering practical ways to integrate infrared therapy into your routine. Whether you’re looking to recover faster, improve your mood, or support long-term health, this episode delivers the tools you need to take your biohacking game to the next level. Special Offer: Use code “DAVE” at sunlighten.com to get up to $1,000 off until December 6th! Sponsors: -ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. -fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Resources: • Sunlighten Saunas Website – https://www.sunlighten.com/dave/?utm_source=DaveAsprey&utm_medium=Partner&utm_content=Podcast&leadsource=DaveAsprey&utm_campaign=DaveAsprey • Sunlighten Saunas on Instagram – https://www.instagram.com/sunlightensaunas/ • 2025 Biohacking Conference – https://biohackingconference.com/2025 • Dave Asprey’s Website – https://daveasprey.com • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books • Danger Coffee – https://dangercoffee.com • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ • Dave Asprey’s Linktree – https://linktr.ee/daveasprey • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com • Own an Upgrade Labs – https://ownanupgradelabs.com • Upgrade Labs – https://upgradelabs.com • 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com Timestamps • 00:00 Introduction to Infrared Saunas • 00:27 Meet Connie Zack: Leading Voice in Infrared Saunas • 00:50 The Science Behind Infrared Saunas • 02:35 Infrared Saunas vs. Traditional Saunas • 05:41 Health Benefits of Infrared Saunas • 08:14 Technological Advancements in Infrared Saunas • 17:36 The Role of LEDs in Infrared Saunas • 22:37 Practical Tips and Personal Experiences • 28:14 Detoxing and Energizing with Glutathione • 28:40 Pre and Post-Sauna Rituals • 29:05 Habit Stacking in the Sauna • 29:41 Managing Overheating Devices • 31:05 Creative Breakthroughs in the Sauna • 32:14 Scientific Method and Personal Experience • 36:05 Understanding Glucose Spikes • 38:44 Longevity Benefits of Infrared Saunas • 43:27 Infrared Saunas and Skin Health • 45:29 Extreme Detox Protocols • 48:28 Grip Strength and Longevity • 50:34 Customizing Your Sauna Experience See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 14, 2024

What if you could command any room and set boundaries without saying a word? Dave Asprey sits down with Kasia Urbaniak, founder and CEO of The Academy—a trailblazing school where women learn the true principles of influence and authority. Kasia brings a unique and dynamic perspective, drawing on nearly two decades of experience that includes working as a professional Dominatrix, practicing Taoist alchemy in one of China’s oldest female-led monasteries, and earning certifications across disciplines like Medical Qi Gong and Systemic Constellations. Here’s what you’ll learn in this episode: • How to set clear, unbreakable boundaries in any situation • Techniques for wielding influence without sacrificing integrity • Tools to reclaim inner authority and navigate life with confidence • Practical strategies for handling power dynamics in relationships, work, and beyond Kasia’s methods have empowered over 4,000 women worldwide to step into leadership roles in every sphere, from personal relationships to professional arenas. In this episode, she shares practical insights on transforming how you’re perceived by others and, more importantly, how you perceive yourself. Whether you’re navigating complex workplace dynamics, strengthening personal boundaries, or seeking clarity in relationships, Kasia’s teachings offer a path to reclaiming the powerful, authentic authority within you. Sponsors -Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. -LMNT | Free LMNT Sample Pack with any drink mix purchase by going to https://drinklmnt.com/dave. Resources: • 2025 Biohacking Conference – https://biohackingconference.com/2025 • Kasia Urbaniak’s Website – https://www.kasiaurbaniak.com • Kasia Urbaniak’s Book: Unbound: A Woman’s Guide to Power – https://www.kasiaurbaniak.com/unbound • The Academy – Practical Training for Women on Power and Influence – https://www.kasiaurbaniak.com/the-academy • Kasia Urbaniak on Instagram – https://www.instagram.com/kasiaurbaniak/ • Dave Asprey’s Website – https://daveasprey.com • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books • Danger Coffee – https://dangercoffee.com • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ • Dave Asprey’s Linktree – https://linktr.ee/daveasprey • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com • Own an Upgrade Labs – https://ownanupgradelabs.com • Upgrade Labs – https://upgradelabs.com • 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com Timestamps: • 00:00 Introduction to the Human Upgrade • 01:07 Meet Kasia Urbaniak: Author of Unbound • 02:52 Exploring Power Dynamics • 04:46 The Role of Emotions in Power • 14:50 Embodiment and Somatic Work • 32:58 The Power of Voice and Presence • 48:22 Collective Intelligence and Intuition • 54:50 Facing Fears and Intuition • 55:15 Male vs. Female Intuition • 56:01 The Power of Erotic Energy • 57:13 Welcoming Emotions and States • 59:10 Role-Playing and Personas • 01:00:06 Teaching Women to Speak Up • 01:02:04 Energetic Dynamics in Relationships • 01:04:35 Victimhood and Healing • 01:19:54 The Power of Asking • 01:29:40 Money and Emotional Alchemy • 01:31:53 Shameless Money Conversations • 01:44:00 Final Thoughts and Upcoming Events See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 12, 2024

Is unlocking the full potential of your brain even possible, or just a myth from the movie Limitless ? In this eye-opening episode, neuroscientist and author Dr. Mithu Storoni joins Dave to dive deep into the science of brain optimization for hyper-efficient work performance. Together, they break down the surprising roles of astrocytes in supporting neurons, the influence of the brain’s “blue dot” region (the locus coeruleus) on focus and mental clarity, and how harnessing neuroplasticity can lead to improved cognitive efficiency and resilience in high-stress environments. Get ready to discover actionable science-backed hacks for enhancing work productivity and maintaining focus—even in the face of constant distractions. Dr. Storoni also explains how optimizing your breathing rhythm, managing your brain’s arousal state, and tapping into the natural flow of ultradian rhythms can dramatically improve your mental output. Whether you’re looking to elevate your workflow, supercharge your mental performance, or unlock the science of hyper-efficiency, this episode delivers essential strategies to cultivate a high-performing mind for work and beyond. Tune in to understand how the latest neuroscience can transform how you think, focus, and excel every day. Sponsors -Quantum Upgrade | Go to Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. -Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. Resources: • Dr. Mithu Storoni’s Website – https://www.mithustoroni.com • Hyper Efficient: Optimize Your Brain to Transform the Way You Work by Dr. Mithu Storoni – https://www.hachettebookgroup.com/titles/mithu-storoni/hyperefficient/9780316566933/ • Dr. Mithu Storoni on Facebook – https://www.facebook.com/drmithustoroni/ • Dr. Mithu Storoni’s LinkedIn – https://www.linkedin.com/in/mithu-storoni-0488872a/ • Dave Asprey’s Website – https://daveasprey.com • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books • Danger Coffee – https://dangercoffee.com • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ • Dave Asprey’s Linktree – https://linktr.ee/daveasprey • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com • Own an Upgrade Labs – https://ownanupgradelabs.com • Upgrade Labs – https://upgradelabs.com • 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com Timestamps • 00:00 – Introduction to Brain Complexity • 00:29 – The Human Upgrade with Dave Asprey • 01:42 – Meet Dr. Mijtu Storoni • 02:16 – Understanding Brain Efficiency • 02:57 – The Role of Astrocytes • 04:37 – Brain Adaptability and Environment • 06:55 – Biohacking and Environmental Signals • 08:34 – Power vs. Efficiency Debate • 11:26 – The Importance of Glial Cells • 18:10 – The Brain as a Predictive Machine • 23:14 – Nutrition and Brain Health • 32:33 – The Gut-Brain Connection • 36:36 – Eye Health as a Proxy for Brain Health • 40:47 – Aligning the Brain: The Blue Dot Network • 41:54 – Understanding Brain Gears and Stress Management • 42:27 – Maintaining the Goldilocks Zone for Optimal Brain Function • 43:09 – The Role of Creativity and Daydreaming • 44:28 – Strategies to Stay in Optimal Mental States • 47:44 – Biohacking for Enhanced Efficiency • 51:00 – The Science Behind Flow States • 57:09 – Harnessing Innate Curiosity for Mental Efficiency • 01:03:46 – Breathing Techniques for Mental Regulation • 01:13:32 – The Importance of Ultradian Rhythms • 01:17:40 – Practical Tips for Efficient Breaks • 01:21:20 – Conclusion: Embracing Hyper Efficiency See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 7, 2024

What if the keys to an extraordinary life lie in choices most people wouldn’t dare to make? In this iconic, unearthed episode, best-selling author and performance pioneer Tim Ferriss joins Dave Asprey to spill the unfiltered truth on smart drugs, insect protein, and the surprising links between sex, creativity, and high performance. They dig into cutting-edge topics still sparking curiosity today: the calculated risks and rewards of smart drugs, the future-forward benefits of insect protein, and how unconventional habits fuel creativity and peak performance. Tim candidly shares his personal protocols, from routine blood testing to strategic supplementation, all rooted in his philosophy that “the dose makes the poison.” As a powerful wrap-up, Tim lays out his top three life principles for real success: choosing high-caliber people, focusing on those who “get it,” and setting audacious, even wild, goals. Whether you’re biohacking or simply intrigued, this episode delivers timeless insights and bold ideas for anyone ready to unlock a high-performance life. Sponsors -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. -Pendulum | Go to https://pendulumlife.com/ and use code Asprey20 for your first month of GLP-1 or any Pendulum formula. Resources: • Tim Ferriss’ Website – https://tim.blog • Tim Ferriss’ Book Club – http://fourhourbook.club/ • Tim Ferriss’ Podcast – https://tim.blog/podcast/ • Dave Asprey’s Website – https://daveasprey.com • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books • Danger Coffee – https://dangercoffee.com • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ • Dave Asprey’s Linktree – https://linktr.ee/daveasprey • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com • Own an Upgrade Labs – https://ownanupgradelabs.com • Upgrade Labs – https://upgradelabs.com • 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com Timestamps • 00:00 Introduction to Early Episodes • 00:57 The Human Upgrade with Tim Ferriss • 01:58 Smart Drugs and Their Effects • 05:09 Experimenting with Health and Performance • 13:53 The Role of Creativity and Writing • 17:05 Exploring Nutrition and Insect Protein • 21:01 Handling Criticism and Audience Responsibility • 30:04 Sex, Performance, and Longevity • 33:21 Tim Ferriss’ Top Three Life Tips See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 5, 2024

What if everything you believe about happiness is wrong? In this episode, Harvard professor and world-renowned happiness expert Arthur Brooks joins Dave Asprey to unlock the secrets of real happiness, revealing the science behind joy, resilience, and lasting fulfillment. As a bestselling author and co-author with Oprah Winfrey of Build the Life You Want , Arthur has spent decades helping people rethink happiness through a blend of psychology, neuroscience, and ancient wisdom. Together, Dave and Arthur explore eye-opening topics like the “reverse bucket list,” why dopamine-driven goals often lead to disappointment, and how embracing discomfort can actually create deeper contentment. Arthur dives into why our common pursuits of fame, wealth, and success often fall short, and shares powerful strategies for mastering what’s within our control, building resilience, and finding meaning in life’s simplest moments. From managing dopamine to harnessing the power of small wins, this episode offers science-backed insights and practical tools to elevate your life with lasting joy and purpose. If you’re ready to transform your approach to happiness, tune in for strategies that truly work. Sponsors Leela Quantum | Head to https://leelaq.com/DAVE for 10% off. ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. Resources: • Arthur Brooks’ Website – https://arthurbrooks.com • Arthur Brooks’ TED Talk: A New Way to Think About Happiness – https://www.ted.com/talks/arthur_brooks_the_art_and_science_of_happiness?subtitle=en&geo=es • Arthur Brooks’ Weekly Column: How to Build a Life in The Atlantic – https://www.theatlantic.com/author/arthur-c-brooks/ • Dave Asprey’s Website – https://daveasprey.com • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books • Danger Coffee – https://dangercoffee.com • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ • Dave Asprey’s Linktree – https://linktr.ee/daveasprey • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com • Own an Upgrade Labs – https://ownanupgradelabs.com • Upgrade Labs – https://upgradelabs.com • 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com Timestamps • 00:00 – Introduction to Reverse Bucket List • 00:35 – The Science of Happiness • 00:58 – Personal Journey to Happiness • 01:44 – Meet Arthur Brooks • 04:26 – The Role of Music in Emotions • 07:43 – Understanding Emotions and the Brain • 09:50 – Parenting and Influence • 18:06 – Public Speaking and Performance • 34:10 – Striving for Success and Happiness • 39:40 – The Struggle with Body Image and Nutrition • 40:03 – Reverse Bucket List: Assessing Attachments • 40:57 – The Science of Dopamine and Motivation • 43:09 – The Dangers of Pornography and Dopamine • 44:03 – Biohacking and Pain Management • 47:03 – The Importance of Small Wins • 48:48 – Embracing Pain and Discomfort • 53:01 – The Role of Pain in Personal Growth • 56:12 – The Concept of Non-Resistance • 57:17 – The Happiness of Strivers • 01:01:13 – The Importance of Relationships and Spiritual Life • 01:03:22 – The Role of Fame and Legacy • 01:16:31 – The Value of Truthfulness and Compassion • 01:17:59 – Conclusion and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 31, 2024

Explore the science and potential of hypnosis as Dr. David Spiegel, Stanford’s leading expert in mind-body medicine, joins Dave Asprey to reveal how hypnosis can radically enhance cognition, mental clarity, and resilience. In this episode of The Human Upgrade , you’ll learn how hypnosis influences the brain’s most vital networks, including the default mode network and executive control, to break mental barriers and amplify focus, perception, and healing. Discover how hypnosis, unlike traditional meditation or neurofeedback, accelerates response times, manages pain, and even helps alleviate PTSD. Dr. Spiegel shares stories of patients overcoming chronic pain and trauma through self-hypnosis, and details the mechanisms that make hypnosis a powerful tool for emotional and physical transformation. Dive into the fascinating brain science behind the practice, from theta brainwave induction to deep sensory modulation, and learn simple self-hypnosis techniques that can elevate mental performance, improve sleep quality, and instill lasting calm. If you’re seeking a powerful, accessible way to biohack your brain and harness the potential of your mind, this episode delivers the insights and tools you need to make hypnosis your ultimate cognitive upgrade. Sponsors Quantum Upgrade | Go to Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Resources: • Dr. David Spiegel’s Website – https://med.stanford.edu/profiles/david-spiegel • Reveri Hypnosis App – https://reveri.com (available on App Store and Google Play) • Dave Asprey’s Website – https://daveasprey.com • Danger Coffee – https://dangercoffee.com • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ • Dave Asprey’s Linktree – https://linktr.ee/daveasprey • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com • Own an Upgrade Labs – https://ownanupgradelabs.com • Upgrade Labs – https://upgradelabs.com • 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement https://40yearsofzen.com Timestamps • 00:00 – Introduction to Hypnosis • 00:59 – Dave Asprey Introduces Dr. David Spiegel • 02:03 – Dr. Spiegel’s Journey into Hypnotherapy • 06:06 – The Power of Hypnosis in Medical Practice • 11:19 – Understanding Hypnosis and Brain Function • 16:14 – Hypnosis for PTSD and Trauma • 19:33 – Hypnosis vs. EMDR: Key Differences • 22:30 – Pain Management through Hypnosis • 31:06 – The Impact of Psychedelics on Cancer Patients • 33:04 – Exploring Psychedelic-Assisted Neurofeedback • 34:05 – Neuroimaging and Brain Activity in Hypnosis • 35:22 – Hypnosis and Cognitive Enhancement • 38:53 – Hypnosis for Sleep and Stress Management • 42:26 – Hypnosis and the “Manchurian Candidate” Concept • 48:21 – Hypnosis and the Immune System • 53:11 – Live Hypnosis Session with Dave Asprey • 58:46 – Conclusion and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 29, 2024

Unlock the mastermind secrets to cognitive enhancement as Dave Asprey shares his ultimate brain-boosting biohacks in this powerful episode of The Human Upgrade . Discover how Dave elevated his IQ, reversed Asperger’s, and overcame brain fog through advanced neurofeedback, BDNF-boosting supplements, mitochondrial enhancers, and the power of the groundbreaking 40 Years of Zen program. Explore revolutionary techniques, from ancient meditation practices to modern nootropics and smart drugs, all designed to amplify memory, focus, and resilience. Learn the science behind cognitive enhancement, from ketones like C8 MCT oil to essential supplements like Vitamins D, K, A, and magnesium that fuel optimal brain function. If you’re seeking proven methods to enhance neuroplasticity, boost mental endurance, or reduce brain fog, this episode is packed with actionable insights. Whether you’re aiming to maximize mental performance or unlock the latest in brain science, Dave’s mastermind approach offers a comprehensive guide to upgrading your mind and achieving peak potential. Prepare to boost cognitive abilities, harness your mind’s true power, and achieve new levels of clarity with Dave’s most effective brain and body biohacks—culminating in the transformative experience of 40 Years of Zen. Sponsors 40 Years of Zen | Neurofeedback training for advanced cognitive enhancement https://40yearsofzen.com/upgrade/ Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Pendulum | Go to https://pendulumlife.com/ and use code Asprey20 for your first month of GLP-1 or any Pendulum formula. Resources: • Dave Asprey’s Website – https://daveasprey.com • Danger Coffee – https://dangercoffee.com • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ • Dave Asprey’s Linktree – https://linktr.ee/daveasprey • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com • Own an Upgrade Labs – https://ownanupgradelabs.com • Upgrade Labs – https://upgradelabs.com • Mendi Neurofeedback Device – Home neurofeedback device for attention and focus improvement https://www.mendi.io • Ketone IQ by HVMN – Go to https://ketone.com/dave for 30% off your first subscription of Ketone IQ. • Qualia NAD – Support for mitochondrial function and cellular energy https://qualialife.com/dave (use code DAVE for discounts) • Vitamin DAKE – Fat-soluble vitamin complex designed by Dave Asprey https://vitamindake.com • Minerals 101 – Comprehensive mineral supplement for cognitive and metabolic support https://shopsuppgradelabs.com/products/minerals-101 Timestamps: • 00:00 Intro • 00:32 Introduction to Cognitive Enhancement • 01:41 Dave’s Personal Journey and Struggles • 04:15 Discovering Cognitive Enhancement Tools • 11:36 Exploring Neurofeedback and Brain Training • 14:22 The Power of Mitochondria and Neuroplasticity • 23:45 Supplements for Cognitive Enhancement • 32:33 The Role of NAD+ in Brain Function • 34:41 Foundational Supplements for Brain Health • 36:17 Essential Supplements for Cognitive Function • 37:29 The Importance of Magnesium and Zinc • 39:14 Meditation and Breath Work for Brain Health • 40:07 Avoiding Toxins for Better Brain Function • 42:56 The Impact of EMFs on Brain Health • 46:25 Neurofeedback and Cognitive Enhancement • 01:05:01 The Power of Ketamine in Neurofeedback • 01:09:49 Final Thoughts and Recommendations • 01:09:49 Testimonials See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 25, 2024

Unlock the secret to cellular detox and discover how to cleanse your body from the inside out with Dave Asprey and Jessica Berman in this episode of The Human Upgrade . Explore cutting-edge detox strategies using phosphatidylcholine, Tudca, and butyrate, three powerful molecules designed to remove toxins, microplastics, and endocrine disruptors from your system. Jessica, co-owner of BodyBio, reveals how these products support not just detoxification, but also optimize mitochondrial function, enhance brain performance, and improve overall cellular health. From phosphatidylcholine’s ability to restore cell membranes to Tudca’s role in liver health, you’ll learn how to protect yourself from the daily onslaught of environmental toxins that can harm your longevity and vitality. If you’ve been searching for how to reduce your toxic load, flush out microplastics, or boost cognitive function, this episode is packed with actionable insights. Whether you’re a biohacker looking to enhance your cellular resilience or someone curious about how these supplements can improve your overall health, this episode will take your detox game to the next level. Get ready to learn how to detox like a pro, rebuild your cell membranes, and optimize your brain and body with these game-changing biohacks! Resources: • BodyBio Phosphatidylcholine, Tudca, Butyrate & More – Get 25% off BodyBio products with code DAVEASPREY https://bodybio.com/collections/dave-asprey?affluencerId=Dave%20Asprey&linkId=Dave%20Asprey_Clear%20It%20All_Podcast • Dave Asprey’s Website – https://daveasprey.com • The Human Upgrade Podcast – https://daveasprey.com/category/podcasts/ • Danger Coffee – https://dangercoffee.com • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ • Dave Asprey’s Linktree – https://linktr.ee/daveasprey • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com • Own an Upgrade Labs – https://ownanupgradelabs.com • Upgrade Labs – https://upgradelabs.com Timestamps: • 00:00 Intro • 00:30 Introduction and Importance of Grass-Fed Barbecue • 01:03 The Ubiquity of Environmental Toxins • 01:39 Minimizing Exposure and Detoxification • 02:47 Introducing Jessica Berman and BodyBio • 04:41 Understanding Cell Membranes • 08:55 Phosphatidylcholine and Its Benefits • 27:54 Clinical Observations and Future Research • 36:49 The Reality of Modern Toxins • 37:00 Understanding Lipophoric Toxins • 37:44 Detoxification Strategies • 38:30 The Role of Phospholipids • 39:16 Liver Health and Detox • 40:29 The Benefits of Tudca • 41:24 Choline and Fatty Liver • 42:20 Debunking TMAO Myths • 44:28 Soy Lecithin vs. Sunflower Lecithin • 47:21 Mitochondrial Health and Prenatal Care • 50:03 Biohacking for Healthy Aging • 55:35 The Importance of Phospholipids for Cognitive Health • 59:12 Mold Toxins and Health • 01:01:45 Building Resilient Humans • 01:05:02 Exclusive Offer for Listeners See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 24, 2024

Step into the future of sports performance with The Human Upgrade as Dave Asprey and Aron D’Souza, founder of the Enhanced Games, uncover the controversial world of steroids, gene therapy, peptides, and human enhancement. In this groundbreaking episode, they explore how athletes can push the boundaries of physical and mental performance by embracing cutting-edge science once banned by traditional sports bodies like the Olympics. Discover why the Enhanced Games are redefining fairness in athletics, allowing competitors to use biohacking and performance-enhancing technologies to unlock new levels of strength, speed, and recovery. Aron breaks down the ethical dilemmas, the science behind enhancements, and why athletes should have full control over their bodies and biology. From synthetic growth hormones to the latest in gene therapy, this episode dives deep into the future of sports innovation. Whether you’re fascinated by the world of biohacking, curious about the next big revolution in sports, or want to understand how gene therapy and performance enhancers could impact human longevity, this episode delivers a thought-provoking look into the possibilities of superhuman performance. Could you be the world’s next super athlete? Age might soon be irrelevant! The future of athletic potential is wide open—are you ready to take the leap? Sponsors : Omni-Biotic | Visit omnibioticlife.com/dave and use code DAVE20 for 20% off. Puori | Visit https://puori.com/dave and use code DAVE for 20% storewide. Resources: • Enhanced Games – https://enhanced.org • Enhanced Games Instagram – https://www.instagram.com/enhanced_games/ • Dave Asprey’s Website – https://daveasprey.com • The Human Upgrade Podcast – https://daveasprey.com/category/podcasts/ • Gene Therapy for Longevity – https://daveasprey.com/genetherapy • Danger Coffee – https://dangercoffee.com • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ • Dave Asprey’s Linktree – https://linktr.ee/daveasprey • Dave Asprey’s Book Smarter Not Harder – https://daveasprey.com/books • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com • Own an Upgrade Labs – https://ownanupgradelabs.com • Upgrade Labs – https://upgradelabs.com Timestamps: • 00:00 – The Toxic Belief System • 00:31 – Introduction to the Human Upgrade • 02:42 – The Enhanced Games Concept • 04:12 – Olympic Inequality and Corruption • 05:19 – The Case for Performance Enhancements • 10:54 – Transparency and Financial Incentives • 15:30 – Health and Safety in Enhanced Games • 18:14 – Global Impact and Future of Enhanced Games • 25:28 – Cognitive vs. Physical Enhancements • 28:54 – Historical Context and Future Vision • 33:54 – Human Enhancements and Banned Substances • 34:36 – The Enhanced Games: Concept and Vision • 35:53 – Biohacking and Cognitive Enhancers • 36:24 – The Birth of the Enhanced Games • 37:00 – Data and the Future of Sports • 40:20 – Criticism and Scientific Debate • 42:03 – Ethics and Sponsorship • 47:55 – Gender and Competition Categories • 54:41 – Funding and Logistics of the Enhanced Games • 57:06 – The Future of Sports and Human Potential • 57:46 – Technological and Engineered Enhancements • 01:04:16 – Getting Involved and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 22, 2024

Unlock the power of continuous glucose monitoring (CGM) and transform your health in this eye-opening episode with Dave Asprey. Discover why tracking your blood sugar 24/7 isn’t just for diabetics—it’s the key to unlocking peak health, optimizing your metabolism, and preventing chronic diseases. Joined by Levels founder and biohacker Josh Clemente, Dave dives into the real science behind CGMs and how they provide unparalleled insights into how your diet, sleep, and exercise affect your blood glucose. You’ll learn how glucose spikes are linked to aging, inflammation, and energy crashes, and why keeping your blood sugar stable can help you boost mental clarity, enhance longevity, and even prevent conditions like diabetes and heart disease. Josh reveals the engineering mindset behind building Levels and how this game-changing technology is revolutionizing the way we understand metabolic health. With insider data from 50,000+ users, you’ll discover how simple lifestyle tweaks—like post-meal walks, sleep optimization, and personalized nutrition—can dramatically improve your health outcomes. This episode is a must-listen for anyone serious about biohacking, metabolic control, and optimizing every aspect of their health through real-time data. Learn how to take control of your body and get ahead of the game in the future of health monitoring. Sponsors: Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. OneSkin | Go to https://oneskin.co/ and use code ASPREY15 for 15% off your purchase. Resources: • Levels : Visit https://levels.link/daveasprey to get two extra months of membership with Levels. • Levels Instagram : https://www.instagram.com/levels • Josh Clemente Instagram : https://www.instagram.com/joshuasforrest • Dave Asprey’s Linktree : https://linktr.ee/daveasprey • Dave Asprey’s Book Smarter Not Harder : https://daveasprey.com/books • Danger Coffee by Dave Asprey : https://www.instagram.com/dangercoffeeofficial/ • Upgrade Collective : Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs : https://ownanupgradelabs.com Timestamps: • 00:00 - Introduction to Personal Data Rights • 00:38 - The Importance of Blood Sugar Monitoring • 01:16 - Dave Asprey’s Journey with Glucose Monitoring • 02:47 - The Evolution of Continuous Glucose Monitors • 03:31 - Installing the New Levels Sensor • 04:39 - The Role of Data in Biohacking • 05:47 - From SpaceX to Glucose Monitoring • 09:49 - The Need for Better Health Data • 13:25 - The Intersection of Engineering and Health • 20:25 - The Future of Personalized Health Data • 28:46 - The Impact of Continuous Glucose Monitoring • 35:45 - Levels’ Research and Findings • 40:28 - Understanding Food Logging and Blood Sugar Response • 41:14 - The Struggle with Weight Loss and Willpower • 41:56 - The Role of Different Foods in Blood Sugar Management • 44:32 - Biohacking and Personalized Nutrition • 49:30 - The Impact of Sleep on Blood Sugar Control • 55:23 - The Future of Health Monitoring and AI • 59:19 - Practical Tips for Blood Sugar Management • 01:02:01 - The Importance of Tracking Health Metrics • 01:15:35 - Blood Sugar and Cognitive Function • 01:21:01 - Final Thoughts and Recommendations See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 18, 2024

Get ready to discover the true superfoods that can transform your health—starting with spirulina and chlorella. In this dynamic and thought-provoking episode, Dave Asprey welcomes Catharine Arnston, founder of ENERGYbits, to dive deep into the world of algae and its incredible potential to boost energy, detox the body, and support longevity. First, we challenge the myths around trendy “superfoods” and reveal why algae, particularly spirulina and chlorella, reign supreme for mitochondrial health and cellular energy. Catharine shares her 15 years of research on algae, explaining how it protects your cells, enhances brain function, and even supports cancer prevention. Next, we explore cutting-edge science on how algae supercharge mitochondrial performance, with Catharine revealing new clinical trial data that shows a 20% boost in mitochondrial function in just seven days. Finally, we break down the real-life impacts—improved brainpower, glowing skin, and detoxified cells—showing how this powerhouse algae can revolutionize the way you think about your health. This episode will change the way you approach superfoods and biohacking forever. Resources: ENERGYBits: Visit energybits.com and use code UPGRADE for 20% off your order. ENERGYbits Instagram: https://www.instagram.com/energybits/ Dave Asprey’s Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book Smarter Not Harder : https://daveasprey.com/books Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Join The Human Upgrade Podcast Live – Upgrade Collective: https://www.ourupgradecollective.com Own an Upgrade Labs: https://ownanupgradelabs.com Timestamps: • 00:00 – You Won’t Believe This • 00:39 – Introduction to Superfoods • 01:24 – The Benefits of Algae • 02:20 – Guest Introduction: Catharine Arnston • 03:19 – Catharine’s Journey to Algae • 04:16 – The Science Behind Algae • 05:22 – Mitochondria and Algae • 05:53 – The Role of Superoxide Dismutase (SOD) • 06:24 – Alkaline Diets and Health • 22:20 – Phycocyanin: The Cancer-Fighting Pigment • 29:52 – Clinical Trials and Future Research • 31:31 – Spirulina Efficacy Study • 32:12 – Mitochondrial Health Insights • 32:56 – Intermittent Fasting vs. Spirulina • 35:27 – Testimonials and Real-Life Benefits • 39:52 – Quality Control and Safety • 43:31 – Skin Health and Algae • 47:34 – Dosing and Usage Tips • 48:18 – Brain Health and Recovery • 50:57 – Aging and Biohacking • 53:39 – Final Thoughts and Offers See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 17, 2024

Today, we’re diving into the age old question, what is the purpose of your life? We chat about the science behind emotional intelligence with Dr. John Demartini, creator of the groundbreaking Demartini Method. In this thought-provoking episode, Dr. Demartini reveals how his unique approach to personal development and emotional mastery can help you uncover your highest values and transcend emotional chaos. We explore how the quality of the questions you ask shapes the quality of your life, providing a roadmap to unlock your fullest potential. First, we dig into the hidden order of the universe, showing how the Demartini Method guides you to balance emotion, intuition, and inspiration for greater control and fulfillment in life. Then, we break down Dr. Demartini’s journey—overcoming learning challenges, mastering the mind-body connection, and developing a method that has transformed lives around the globe. Finally, Dr. Demartini shares actionable strategies for tapping into your innate brilliance, balancing your values, and discovering the magnificence already within you. This episode will shift your perspective on personal growth, purpose, and the power of self-awareness. Sponsors : ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. Quantum Upgrade | Go to Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. Resources : Dr. John Demartini’s Website: https://drdemartini.com/ Dr. John Demartini’s Instagram: www.instagram.com/drjohndemartini Dr. John Demartini’s YouTube: www.youtube.com/c/drdemartini Dave Asprey’s Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com Join The Human Upgrade Podcast Live – Upgrade Collective: https://www.ourupgradecollective.com Own an Upgrade Labs: https://ownanupgradelabs.com Timestamps and Highlights : • 00:00 - Introduction to Dr. John Demartini • 01:56 - The Demartini Method Explained • 04:53 - Delegating and Managing Stress • 08:19 - Journey to Mastery and Overcoming Challenges • 15:08 - The Power of Reading and Learning • 22:57 - Transforming Education in South Africa • 28:39 - Integration of Knowledge and Universal Principles • 34:23 - Understanding Emotions and Intuition • 35:09 - The Role of Intuition in Awareness • 35:41 - Inspiration and Full Consciousness • 37:31 - The Hidden Order in the Universe • 40:17 - The Concept of Divine Guidance • 45:52 - The Neuroscience of Divine Order • 54:56 - The Demartini Method and Human Behavior • 59:18 - Applying the Demartini Method • 01:05:00 - The Breakthrough Experience • 01:07:49 - Final Thoughts and Gratitude See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 15, 2024

Today, we’re unlocking the full potential of your brain—starting with Bryan Johnson’s Blueprint for longevity and brain optimization. We’re revisiting our conversation with Bryan, the creator of the Don’t Die movement (among many other things), to explore how his groundbreaking approach to brain health and biohacking is reshaping the future of longevity. First, we dive into Bryan’s mission to make brain monitoring as easy as tracking blood glucose, using his Blueprint protocol to measure and optimize cognitive performance for better health and wellness. Then, we tackle the deeper side of biohacking—longevity, societal reactions to living longer, and how to handle critics when you’re pushing the limits of human potential. Finally, Bryan shares his personal journey—investing $80M into brain science, building the Blueprint for optimal living, and discovering the power of community and lifelong friendships for a long, vibrant life. This episode will change the way you think about brain health and the future of humanity. Sponsors : Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. Resources : Bryan Johnson’s Blueprint Protocol: https://blueprint.bryanjohnson.com/ Bryan Johnson’s Don’t Die Movement: https://dontdie.bryanjohnson.com/ Bryan Johnson’s Kernel: https://www.kernel.com/ Bryan Johnson’s YouTube Channel: https://www.youtube.com/@bryanjohnson_ Bryan Johnson’s Instagram: https://www.instagram.com/bryan_johnson_ Dave Asprey’s Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com Join The Human Upgrade Podcast Live – Upgrade Collective: https://www.ourupgradecollective.com Own an Upgrade Labs: https://ownanupgradelabs.com Timestamps and Highlights : 00:00 Introduction and Bold Claims 00:39 Meet Bryan Johnson: The Neuroscience Pioneer 01:23 Kernel: Revolutionizing Brain Measurement 05:51 Biohacking and Longevity 07:30 Facing Criticism and Staying Resilient 16:06 Media Training Insights 19:49 Personal Reflections and Relationships 34:37 Exercise and Longevity 44:46 Optimizing Brain-Body Interface 45:25 Longevity Hacks and Driving Preferences 45:48 Debating Olive Oil and Saturated Fats 46:52 The Blueprint Approach to Health 48:38 Testing and Metrics in Health 52:22 Testosterone and Hormone Protocols 56:27 Exploring Semen Retention 01:00:44 Body Hair and Aesthetics 01:04:26 Psychedelics and Consciousness 01:08:32 Audience Q&A and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 11, 2024

Today, we’re diving deep into biohacking your body’s performance—starting with your VO2 max and mitochondria. We’re sitting down with cellular optimization expert, Rowena Gates, to dive into how the NanoVi device is disrupting the world of biohacking, recovery, and training. First up, we’re breaking down VO2 max—the secret sauce to longevity. Forget endless hours of cardio. Learn how to hack your VO2 max efficiently and add years to your life, without grinding it out in the gym. Then, we tackle the hidden world of reactive oxygen species (ROS). These little molecules can be both your friend and foe—boosting energy or fast-tracking aging. We’ll show you how to control them, so you can keep your energy levels high and your body youthful. Finally, we explore the cutting-edge science of protein folding and exclusion zone water. Sound complicated? Don’t worry, we’ll break it down and show how NanoVi tech supercharges your mitochondria, giving you faster recovery and more endurance, all with minimal effort. Sponsors : Eng3 Special Offer Code: https://eng3corp.com/dave/ Resources : Rowena Gates’ Website: https://www.eng3corp.com NanoVi Device: https://www.eng3corp.com/nanov i Rowena Gates’ LinkedIn: https://www.linkedin.com/in/rowenagates/ Dave Asprey’s Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com Join The Human Upgrade Podcast Live – Upgrade Collective: https://www.ourupgradecollective.com Own an Upgrade Labs: https://ownanupgradelabs.com Timestamps and Highlights : 00:00 Introduction to Metabolic Health 00:38 The Importance of VO2 Max 02:34 Reactive Oxygen Species Explained 05:57 The Role of Water in Cellular Health 14:11 Mitochondrial Function and Longevity 20:25 Cognitive Function and Biohacking 21:45 Advanced Meditation and Mitochondria 22:09 Post-Exercise Recovery Insights 22:37 NanoVi and Athletic Performance 23:42 Pro Athletes and Biohacking 27:00 Mitochondrial Function and Health 33:24 NAD and Cellular Health 36:29 Biohacking for Modern Living 37:48 Conclusion and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 10, 2024

Today, we’re hacking your home—big time. I’m sitting down with three experts who know exactly how your living space might be messing with your health, and more importantly, how to fix it. First up, we’ve got Michael Rubino, aka the mold medic , who’s here to blow your mind about the invisible toxins lurking in your walls. Mold? It’s everywhere, and it’s doing more damage than you think. Michael’s got killer insights on why dust might be your biggest health enemy and exactly how to get rid of it before it starts messing with your system. Then, we’ve got Ryan Blaser dropping some serious science on environmental toxins you probably didn’t even know were impacting you. EMFs? VOCs? Ryan explains why your home’s air quality might be worse than you think, and how to fix it with a few smart biohacks. Finally, Matteo Franceschetti, the sleep optimization guru, breaks down how your home could be trashing your sleep. He’s got the secrets to transforming your environment so you can supercharge your recovery and performance every night. Check out the Full Episodes here: • Detox Your Home: How to Improve Indoor Air Quality & Get Rid of Mold – Michael Rubino | 1036 https://www.youtube.com/watch?v=gncPqFlRXho&t=2s • How Mold Affects Your Health & What You Can Do About It – Michael Rubino | 1041 https://www.youtube.com/watch?v=QD5RUcN8uds&t=2s • Improve Your Home Environment & Breathe Better – Michael Rubino | 1045 https://www.youtube.com/watch?v=gncPqFlRXho&t=2s Sponsors : Puori | Visit https://puori.com/dave and use code DAVE for 20% storewide. Calroy | Head to https://calroy.com/dave for an exclusive discount. Resources : Michael Rubino’s Website: https://www.themoldmedic.com Michael Rubino’s Instagram: https://www.instagram.com/mold_medics/ Michael Rubino’s Book: https://www.themoldmedic.com/books Michael Rubino’s Company: https://www.allamericanrestoration.com Ryan Blaser’s Website: https://www.testmyhome.com Ryan Blaser’s Instagram: https://www.instagram.com/testmyhome/ Ryan Blaser’s Blog: https://www.testmyhome.com/blog Matteo Franceschetti’s Website: https://www.eightsleep.com Matteo Franceschetti’s Instagram: https://www.instagram.com/matteofranceschetti Eight Sleep Instagram: https://www.instagram.com/eightsleep Dave’s Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com Own an Upgrade Labs: https://ownanupgradelabs.com Timestamps and Highlights : 00:00 Introduction: The Hidden Dangers in Your Home 00:02 Air Quality and Mold: The Silent Threat 00:40 Furniture Choices for Better Air Quality 01:51 Cleaning and Maintenance Tips 03:00 The Impact of Environmental Toxins 04:04 Formaldehyde and VOCs: Invisible Enemies 07:36 Energy Efficiency vs. Health 11:14 HVAC Systems and Air Filters 21:57 DIY Dust Testing and Home Lab Kits 29:02 Top Indoor Pollutants and Final Thoughts 30:47 Identifying Mold in Your Home 31:46 Health Impacts of Mold Exposure 32:18 Dangers of Air Fresheners and Fragrances 33:23 Improving Indoor Air Quality 35:59 Gas vs. Electric Stoves 37:07 Lighting and Its Effects on Health 40:57 Managing Humidity and Mold in Humid Climates 43:17 Carbon Monoxide: The Silent Killer 46:26 Dealing with VOCs in Your Home 50:38 Importance of Regular Cleaning 52:26 Noise Pollution and Its Impact 53:41 Advanced Sleep Tracking Technology 59:04 The Future of Consumer and Medical Devices See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 8, 2024

What if you could control your brain’s performance and stress levels with just a few simple hacks? In this episode callback, Dave Asprey sits down with Dr. Andrew Huberman, a renowned neuroscientist from Stanford University, to unlock the secrets of how your brain really works—and how you can train it for enhanced cognitive power and stress resilience. From rewiring your brain’s fear response to mastering your level of alertness, Dr. Huberman reveals groundbreaking discoveries that could change the way you approach your mental and emotional well-being. Diving deep into neuroscience, they cover how visual stimuli can modulate stress, the role of autonomic arousal in cognitive performance, and even how brain-machine interfaces may soon push human potential beyond its current limits. You’ll learn why certain visual and sensory techniques can calm or excite your brain, and how to train your brain to handle high-stress situations with ease. Plus, find out how Dr. Huberman is working on curing blindness with VR technology—offering a glimpse into the future of human augmentation. Sponsors: Apollo Neuro | Head to https://apolloneuro.com/DaveAsprey to save 15% on an Apollo wearable. Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Resources : Dr. Andrew Huberman’s Stanford Profile: https://profiles.stanford.edu/andrew-huberman Huberman Lab Podcast: https://hubermanlab.com/podcast Follow Dr. Andrew Huberman on Instagram: https://www.instagram.com/hubermanlab Dave’s Linktree: linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’: daveasprey.com/books Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ Timestamps and Highlights : • 00:00 — Introduction and Cool Fact of the Day • 00:07 — Understanding Anxiety Through Brain Activity • 02:07 — Meet Dr. Andrew Huberman • 03:33 — The Five Components of Life Experience • 05:29 — Autonomic Arousal and Cognitive Performance • 08:00 — Visual Stimuli and Stress Management • 10:22 — Exploring Fear and Courage in Mice • 15:17 — Human Applications and VR Experiments • 23:10 — The Role of Vision in Autonomic Arousal • 29:38 — Bridging Neuroscience and Wellness • 30:43 — Curing Blindness: A Personal Mission • 34:50 — VR Goggles and Visual Stimulation • 35:12 — The Power of Virtual Art Galleries • 35:58 — Exploring Neuroplasticity in Adults • 38:31 — Potential and Risks of VR Technology • 40:27 — Human Augmentation and Neuroscience • 43:22 — Brain-Machine Interfaces and Non-Invasive Techniques • 45:47 — The Evolution of Biohacking • 52:03 — Personal Biohacking Journeys • 56:34 — Longevity and Life Extension • 59:28 — Conclusion and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 3, 2024

Get ready to upgrade your cardiovascular health in a way you’ve never heard of before. Dave Asprey sits down with Dr. Michael Twyman, a pioneering biohacking cardiologist who blends cutting-edge functional medicine with conventional wisdom to help you avoid heart attacks and strokes. If you think cardiovascular disease is inevitable, think again. Dr. Twyman reveals the hidden mechanisms behind heart disease, starting with the misunderstood role of plaque in your arteries and the essential yet underappreciated glycocalyx—a slippery gel-like coating that could be the key to preventing arterial damage. From there, it’s all about prevention, prevention, prevention. Want to know how simple lifestyle tweaks can significantly reduce your risk of cardiovascular events? We’ve got the biohacks—grounding, sunlight exposure, cold plunges, and more—laid out for you in a step-by-step, easy-to-apply format. Dr. Twyman breaks down the crucial role of circadian biology and how aligning your body clock with natural light cycles can help protect your heart. Plus, learn why grounding might just be the ultimate, free anti-inflammatory tool you’ve been missing. This episode isn’t just about tips and tricks—it’s a complete roadmap to understanding and optimizing your heart health. Dave and Dr. Twyman get into the nitty-gritty of lab tests you should be asking for, why exercise is only part of the solution, and how the current medical insurance model fails to protect your cardiovascular future. Don’t miss out on these life-saving insights that are rooted in both ancient wisdom and modern science. Sponsors: Viome | Go to https://viome.com/dave to save $110 on the Full Body Intelligence Test. fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Resources : Calroy Health Sciences: https://calroy.com/ Dr. Michael Twyman’s Website: https://www.apollocardiology.com/ Follow Dr. Michael Twyman on Instagram: https://www.instagram.com/drtwyman Dave’s Linktree: linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’: daveasprey.com/books Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ Timestamps and Highlights : • 00:00 — Introduction to Cardiovascular Health • 01:22 — Meet Dr. Michael Twyman • 05:57 — Understanding Heart Attacks • 08:09 — The Role of Glycocalyx in Cardiovascular Health • 15:17 — Lifestyle Changes for Cardiovascular Health • 24:32 — Exercise and Cardiovascular Health • 27:58 — Effective VO2 Max Strategies • 28:12 — Patient Exercise Goals and Time Management • 29:12 — Thyroid and Cardiovascular Health • 32:49 — Circadian Biology and Heart Disease • 33:57 — Sunlight, Grounding, and Seasonal Health • 38:49 — The Role of Statins in Cardiovascular Health • 43:16 — Key Labs for Cardiovascular Risk Assessment • 50:33 — Insurance and Preventative Health • 54:35 — Conclusion and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 1, 2024

Are you sleeping enough—or just enough to get by? In this episode of The Human Upgrade , Dave Asprey dives into the global sleep crisis and reveals why mastering your sleep is the most important biohack you can do for your health, performance, and longevity. This episode is your ultimate guide to transforming your rest and, by extension, your life. First, sleep scientist Matthew Walker breaks down how sleep deprivation has become a global epidemic, slashing up to 20% of our sleep in the past century. He unpacks the dangers of too little sleep, including its direct link to increased mortality rates and cognitive decline, and discusses the optimal sleep duration for both quantity and quality. Next, Peter Martone shifts the conversation to sleep posture and environment. He shares simple yet effective techniques for optimizing your sleep position to maximize deep, restorative rest. Learn how a small change in your pillow or bed setup can lead to dramatic improvements in your sleep quality and overall health. Finally, Dan Gartenberg dives into the world of sleep biohacking. He reveals groundbreaking research on how sound waves can enhance your deep sleep and how controlling light exposure can unlock better rest. From sleep-tracking tech to environmental optimizations, Dan provides actionable tips to help you take your sleep game to the next level. By the end of this episode, you’ll walk away with expert-backed strategies, biohacking secrets, and sleep science insights that will completely transform the way you sleep—and live. Check out the Full Episodes here: - Sleep is the Boss of You – Matthew Walker, Ph D | 616 https://www.youtube.com/watch?v=cxmtBy0YQjs - Change Your Body Position To Get Better Sleep with Dr. Peter Martone | 819 https://www.youtube.com/watch?v=RKhA3iclRK0 - Sleep Need & Sleep Age Find Out Yours – Dan Gartenberg | 583 https://www.youtube.com/watch?v=XbxB67M-s2A Sponsors : Leela Quantum | Head to https://leelaq.com/DAVE for 10% off. ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. Resources : Matthew Walker’s Website : https://www.sleepdiplomat.com Matthew Walker’s Instagram : https://www.instagram.com/drmattwalker/ Matthew Walker’s Podcast : https://themattwalkerpodcast.buzzsprout.com Matthew Walker’s Book : https://www.amazon.com/Why-We-Sleep-Unlocking-Dreams/dp/1501144316 Peter Martone’s Website : https://www.necknest.com Peter Martone’s Instagram : https://www.instagram.com/peter.martone/ Peter Martone’s YouTube Channel : https://www.youtube.com/user/drpetemartone Peter Martone’s Facebook Group : https://www.facebook.com/groups/necknest Dan Gartenberg’s Website : https://www.sonicsleepcoach.com Dan Gartenberg’s Instagram : https://www.instagram.com/drdansgarden/ Dan Gartenberg’s App : https://www.sonicsleepcoach.com Dan Gartenberg’s TED Talk : https://www.ted.com/speakers/dan_gartenberg Dave’s Linktree : https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now : https://daveasprey.com/books Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective : https://www.ourupgradecollective.com Danger Coffee by Dave Asprey : https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey : https://shopsuppgradelabs.com Own an Upgrade Labs : https://ownanupgradelabs.com Timestamps and Highlights : 00:00 Introduction: The ROI on Sleep 00:24 Global Sleep Loss Epidemic 01:43 Sleep Duration and Mortality Risk 06:23 The Importance of REM Sleep 12:47 Optimizing Sleep Quality 17:37 Technological Interventions for Better Sleep 19:02 Temperature Regulation and Sleep 21:03 Light's Impact on Sleep 24:44 Personal Sleep Hacks and Experiments 33:40 Understanding Lymphatic and Glymphatic Drainage 34:42 Debunking Side Sleeping Myths 35:30 The Importance of Cervical Alignment 37:07 Improving Sleep Quality with Neck Nest 38:00 Audience Questions: TMJ and Sleep 41:07 The Impact of Food and Temperature on Sleep 45:28 Enhancing Sleep with Sound and Technology 01:01:08 The Role of Cortisol in Sleep Quality See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 27, 2024

Dave Asprey is joined again by glutathione expert Nayan Patel to explore the transformative effects of this “master antioxidant” glutaryl. From skin health and detoxification to energy production and mitochondrial function, glutathione plays a critical role in overall wellness. Nayan shares his cutting-edge research on topical glutathione delivery systems that are more effective than IV treatments and help combat oxidative stress. The conversation touches on innovative applications of glutathione for skin lightening (yes, including the surprising trend of butthole bleaching), the impact of environmental toxins, and how to optimize glutathione levels to support longevity and performance. Whether you’re battling oxidative stress, looking to rejuvenate your skin, or just curious about how glutathione can boost your health, this episode has something for everyone. Visit https://aurowellness.com/ and use code Dave10 to get 10% off your order! Resources: Nayan Patel’s Bio: https://www.a4m.com/nayan-patel.html Auro Wellness Instagram: https://www.instagram.com/aurowellness Glutaryl Skin Products: https://aurowellness.com/ Dave’s Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com Timestamps and Highlights : 00:00 Introduction to an Unusual Topic 00:36 The Human Upgrade with Dave Asprey 00:52 The Importance of Glutathione 01:34 Introducing Nayan Patel and Glutaryl 02:05 Benefits of Topical Glutathione 02:36 Personal Health Journey and Skin Care 03:21 Deep Dive into Glutathione Technology 08:13 Glutathione and Skin Health 10:00 Vitamin C and Glutathione 17:54 Diet, Oxidative Stress, and Glutathione 20:26 Detox Reactions and Glutathione 24:26 Using Glutathione for Recovery 26:54 The Cost of Biohacking 27:26 Gene Therapy and Glutathione 28:20 Affordable Alternatives to IV Treatments 29:06 Endocrine Hormones and Glutathione 34:02 Sun Exposure and Skin Care 38:00 Morning and Night Skincare Routines 40:33 Telomeres and Anti-Aging 44:55 Hair Loss and Glutathione 47:12 Conclusion and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 26, 2024

In this transformative episode of The Human Upgrade , three of the world’s foremost experts on sexual wellness—Kim Anami, Susan Bratton, and Emily Morse—explore the depths of sexual mastery, pleasure, and performance. This discussion uncovers the often-overlooked power of sexual energy as a source of personal growth, healing, and vitality. Whether you’re looking to enhance your pleasure, improve your intimate relationships, or explore new dimensions of intimacy, this episode serves as your ultimate guide to unlocking the full potential of your sexual energy. Kim Anami delves into the profound ways sexual energy can be harnessed for personal transformation, teaching how to access life-changing orgasms and deeper intimacy. Susan Bratton brings her expertise to sexual biohacking and the latest technology that can enhance physical pleasure and performance. Emily Morse focuses on breaking down societal taboos around sex and providing actionable advice for better communication and connection with partners. Together, these experts deliver a comprehensive guide to sexual empowerment, sharing actionable techniques that elevate both physical pleasure and emotional connection. By the end of this episode, you’ll have the knowledge to transform your sex life into a source of greater health, energy, and overall well-being. Check out the Full Episodes here: -The Science of Sex: Longevity, Pleasure & Performance - Susan Bratton | 1087 https://youtu.be/3idAK1D85cs -Unleash Your Sexual Potential: Date Nights, Fantasies, and Healing in 'Smart Sex' with Emily Morse https://youtu.be/WyzdS8H__yM - From Holistic Sex to Vaginal Kung Fu with Kim Anami https://youtu.be/zLs3OgwiDSU Sponsors : Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Pendulum | Go to https://pendulumlife.com/ and use code Asprey20 for your first month of GLP-1 or any Pendulum formula. Resources : Kim Anami’s Website : https://kimanami.com Kim Anami’s Instagram : @KimAnami Kim Anami’s Podcast : Orgasmic Enlightenment Kim Anami’s Courses : The Well-F**ked Woman Susan Bratton’s Website : https://susanbratton.com Susan Bratton’s Instagram : @SusanBratton Susan Bratton’s Book : Sexual Soulmates Susan Bratton’s Supplements : The 20 Store Emily Morse’s Website : https://sexwithemily.com Emily Morse’s Instagram : @SexWithEmily Emily Morse’s Podcast : Sex with Emily Emily Morse’s Book : Hot Sex: Over 200 Things You Can Try Tonight Dave’s Linktree : https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now : https://daveasprey.com/books Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective : https://www.ourupgradecollective.com Danger Coffee by Dave Asprey : https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey : https://shopsuppgradelabs.com Own an Upgrade Labs : https://ownanupgradelabs.com Timestamps and Highlights : 00:00 Introduction to Life-Changing Experiences 00:32 Understanding Orgasm Challenges 01:33 Impact of Medications on Sexual Health 02:12 Physical Health and Sexual Arousal 02:56 The Dark Side of Birth Control Pills 06:30 Men's Role in Birth Control Decisions 07:10 Communication in Sexual Relationships 13:25 The Importance of Feeling Safe 16:37 Techniques for Deep Connection 21:26 The Orgasm Gap and Sexual Performance 27:02 Harnessing Sexual Energy for Transformation 33:31 Breathing Techniques for Sexual Energy 34:00 Vaginal vs. Clitoral Orgasms 34:36 The Power of Cervical Orgasms 34:58 Sexual Reflexology and Spiritual Rebirth 35:27 Personal Experiences with Orgasms 36:08 The Anami Guarantee 38:09 Spirituality and Sexuality 40:12 Historical Suppression of Sexual Energy 41:48 Impact of Fifty Shades of Grey 44:22 Pandemic Effects on Sexuality 46:01 Sex Toys and Their Benefits 49:26 Penis Pumps and Male Enhancement 01:01:40 The Importance of Nocturnal Erections See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 24, 2024

In this episode of The Human Upgrade , Dave Asprey sits down with Clint Ober, the pioneer of grounding and earthing technology. Together, they explore the profound effects of reconnecting your body with the Earth’s natural energy through grounding, revealing how this practice can reduce inflammation, optimize mitochondrial function, and enhance overall well-being. Clint explains how he discovered the power of grounding during his career in the cable television industry and how it led him to study its benefits on human health. From studies showing improved cortisol levels and reduced inflammation to anecdotes about athletes using grounding for recovery, this episode delves into the science and personal experiences that highlight the effectiveness of earthing. Sponsors: Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Calroy | Head to https://calroy.com/dave for an exclusive discount. Resources : Earthing Website: earthing.com Follow Clint Ober on Instagram : @clintober Dave’s Linktree: linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’: daveasprey.com/books Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ Timestamps and Highlights : • 00:00:00 — Tour de France • 00:00:30 — Dave Asprey’s Personal Journey with Grounding • 00:02:00 — Welcome Clint Ober: The Grounding Pioneer • 00:04:17 — Clint Ober’s Background and Discovery of Grounding • 00:06:53 — The First Experiments and Observations • 00:18:24 — Initial Studies and Surprising Results • 00:25:54 — Collaboration with Dr. Stephen Sinatra • 00:33:17 — Public Perception and Challenges • 00:35:42 — The Organic Growth of Grounding • 00:36:18 — David Wolfe and the Raw Vegan Movement • 00:36:57 — The Impact of Grounding on Health • 00:38:03 — Grounding in Sports: The Tour de France Story • 00:40:12 — Scientific Evidence and Studies on Grounding • 00:45:37 — Historical Practices of Grounding • 00:48:47 — Grounding Products and Practical Tips • 00:54:51 — The Future of Grounding Technology • 01:05:36 — Final Thoughts and Encouragement See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 19, 2024

In this episode of The Human Upgrade , we dive deep into the mystifying world of quantum energy with guest Philipp Samor von Holtzendorff-Fehling, founder of Leela Quantum Tech and Quantum Upgrade. Together with host Dave Asprey, Philipp unpacks the potential of harnessing quantum energy to enhance human performance, heal the body, and unlock higher consciousness. Philipp discusses how quantum energy has always existed and how modern technology now allows us to access and concentrate it like never before. From personal anecdotes involving quantum blocks to the exploration of biofields and how they influence everything from athletic performance to wound healing, this episode is packed with eye-opening insights. Dave shares his initial skepticism and eventual acceptance of quantum technology after experiencing the benefits firsthand. The conversation covers a range of fascinating topics including energy healing, distributed consciousness, quantum entanglement, and the ethics of working with energy fields. Plus, real-world examples like the flower experiment showcase the tangible effects of quantum energy in everyday life. Sponsors: Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. Fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Resources : Leela Quantum Tech: leelaq.com Quantum Upgrade: quantumupgrade.io Follow Philipp on Instagram: https://www.instagram.com/philipp_vhf/ Dave’s Linktree: linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’: daveasprey.com/books Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ Timestamps and Highlights : • 00:00:00 — Ancient Alien Technology? • 00:00:39 — Show Intro • 00:01:33 — Dave’s Experience with Quantum Technology • 00:04:45 — Introducing Philip Samor von Holtzendorf-Fehling • 00:05:38 — Quantum Technology Explained • 00:06:35 — Personal Experiences with Quantum Devices • 00:11:00 — Understanding Biofields and Energy Healing • 00:15:21 — Philip’s Journey to Quantum Technology • 00:21:22 — Quantum Energy in Sports Performance • 00:26:21 — Exploring Quantum Fields in Cells • 00:27:11 — Quantum Blocks and Distributed Consciousness • 00:27:53 — Quantum Energy and Flower Experiment • 00:28:36 — Leela Quantum and Quantum Upgrade Explained • 00:29:44 — Quantum Entanglement and Location • 00:32:00 — Energy Fields and Geomagnetics • 00:33:53 — Ethics and Integrity in Quantum Energy • 00:36:19 — Scientific Evidence and Blood Studies • 00:40:00 — Wound Healing and ATP Production • 00:41:47 — Autism Clinical Trials and Brainwave Analysis • 00:48:40 — Intuition and Frequency Selection • 00:54:17 — Final Thoughts and Call to Action See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 17, 2024

In this "Best of Nutrition" episode, 3 experts in nutrition share powerful insights on improving your health and performance through optimal eating habits. Listen in as Dr. Mark Hyman, Andrea Bemis, and Shawn Stevenson provide practical tips on boosting energy, improving digestion, and choosing nutrient-dense foods to help you feel your best. Dr. Mark Hyman , a leading expert in functional medicine, dives deep into the importance of nutrient-dense foods and traditional cooking oils like ghee and olive oil. He shares his insights on how these healthy fats support brain health, metabolism, and overall well-being, especially in children. Learn how simple dietary changes can have a significant impact on health. Shawn Stevenson , best-selling author and host of The Model Health Show , breaks down the role of nutrition in optimizing performance and mental clarity. He highlights the science behind choosing the right foods to fuel your body and mind, offering practical tips for enhancing energy and building a sustainable healthy lifestyle. Andrea Bemis , author and advocate for regenerative agriculture, explores how the way we source and grow our food directly affects nutrient quality. She discusses the importance of eating seasonally and locally, providing valuable insights on how to incorporate farm-fresh foods into everyday meals to nourish your body and support the environment. CHECK OUT THE FULL EPISODES NOW! Dr. Mark Hyman: https://youtu.be/TcEgBrfT8LI Shawn Stevenson: https://youtu.be/J2Tq_2Bawig Andrea Bemis: https://youtu.be/bFCASBNah0w Sponsors: Puori | Visit https://puori.com/dave and use code DAVE for 20% storewide. ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. Resources : Mark Hyman’s Website: https://drhyman.com Mark Hyman’s Instagram: @drmarkhyman Andrea Bemis’s Website: https://dishingupthedirt.com Andrea Bemis’s Instagram: @andreabemis Shawn Stevenson’s Website: https://themodelhealthshow.com Shawn Stevenson’s Instagram: @shawnmodel Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ Timestamps and Highlights : 00:00:00 — Introduction by Dave Asprey 00:01:58 — Dr. Mark Hyman on Cooking Oils 00:04:04 — Feeding Kids Nutrient-Dense Meals 00:07:16 — Efficient Cooking and Eating with Kids 00:11:27 — Introducing New Foods to Children 00:12:56 — Listening to Kids’ Intuitive Eating Signals 00:14:28 — Salt in Children's Diets 00:22:32 — Regenerative Agriculture and Nutrient Density 00:31:28 — Finding High-Quality Foods See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 12, 2024

In this episode of The Human Upgrade, gut health experts Dr. Steven Gundry, Dr. Edward Group, and Hannah Kleinfeld share groundbreaking insights into the gut microbiome, detoxification, and the impact of fermented foods on digestion. Discover how caring for your gut can enhance your energy, brain health, and immunity. Check out the Full Episodes here: Dr. Steven Gundry: https://youtu.be/SpO6k9Ofh2E Hannah Kleinfeld: https://youtu.be/zFKHJIX8vtM Dr. Edward Group: https://youtu.be/GV2KnL0wW9M Sponsors : Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Resources : Dr. Steven Gundry's Book, Gut Check: https://drgundry.com Dr. Steven Gundry's Podcast: https://drgundry.com/the-dr-gundry-podcast/ Dr. Steven Gundry’s Instagram: @DrGundry Dr. Steven Gundry's Facebook: Dr. Steven Gundry Global Healing by Dr. Edward Group: https://globalhealing.com Global Healing Instagram: @globalhealingofficial Dr. Edward Group Instagram: @drgroupofficial Omni-Biotic: https://omnibioticlife.com Instagram: @omnibioticlife Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ Timestamps and Highlights : 00:01:00 — Introduction to Gut Health and Parasites with Dr. Steven Gundry 00:06:00 — Fermented Foods & Gut Health with Hannah Kleinfeld 00:12:30 — Probiotics and Detox with Dr. Edward Group 00:18:00 — Practical Steps for a Healthier Gut See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 10, 2024

In this episode of The Human Upgrade , Dave Asprey and Dr. Heather Sandison discuss actionable strategies for optimizing brain health and longevity. Dr. Sandison explains how lifestyle changes, including diet, oral hygiene, and sleep, can help prevent cognitive decline. She also shares insights into the Marama Experience, her revolutionary approach to memory recovery and brain health. Sponsors: Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. Resources : Dr. Sandison’s Website: www.drheathersandison.com Reversing Alzheimer’s Book: https://reversingalzheimersbook.com Dr. Sandison’s Facebook: https://www.facebook.com/HeatherSandisonND Dr. Heather Sandison’s Instagram: https://www.instagram.com/dr.heathersandison/ Dr. Sandison’s TikTok: https://www.tiktok.com/@drheathersandison Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ Timestamps and Highlights : 00:00:01 – Introduction by Dave Asprey 00:02:30 – The Role of Diet in Brain Health 00:07:00 – The Importance of Oral Health in Brain Function 00:12:00 – How Sleep Impacts Cognitive Health 00:17:30 – Key Strategies for Optimizing Cognitive Function 00:22:00 – The Marama Experience: Memory Care to Memory Recovery 00:30:00 – Steps for Protecting Brain Health Over Time See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 6, 2024

In this episode of The Human Upgrade , Dave Asprey talks to Chris Fields, Chief Science Officer at Applied Food Sciences, about the game-changing nootropic AmaTea® Max. They discuss how this natural extract of guayusa delivers long-lasting energy and mental clarity, backed by science and sustainable practices. Learn how AmaTea® Max is revolutionizing cognitive performance, especially for athletes and gamers. Resources : Where to buy products with AmaTea® organic guayusa: https://appliedfoods.com/wheretobuy AmaTea® Max Website: https://appliedfoods.com/amateamax AmaTea® Max Instagram: https://www.instagram.com/appliedfoodsciences Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ Timestamps and Highlights : 00:01 – Why Caffeine is a Super-Powerful Nootropic 04:00 – The Science of Guayusa and AmaTea® Max 07:00 – Cultural Roots and Sustainable Sourcing 11:30 – The Cognitive Benefits of AmaTea® Max 16:20 – How AmaTea® Max Differs from Traditional Caffeine Sources 20:00 – Applications in Gaming and Sports 25:00 – Sustainability and Social Impact See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 5, 2024

In this episode of The Human Upgrade , Dave Asprey welcomes Dr. Jamil Zaki, a professor of psychology at Stanford University and the director of the Stanford Social Neuroscience Lab. Dr. Zaki discusses the critical intersection between empathy, cynicism, and hope, exploring the impacts of negativity bias, cynicism in modern society, and how we can rewire our brains to become more hopeful. Drawing from his latest research and new book, Hope for Cynics , Dr. Zaki shares profound insights on human goodness, how we can challenge our biases, and the practices that can help us foster a more positive outlook on the world. Sponsors : Puori | Visit https://puori.com/dave and use code DAVE for 20% storewide. ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. Resources : Jamil Zaki’s website: jamil-zaki.com Jamil Zaki's New Book: Hope for Cynics: The Surprising Science of Human Goodness Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ Timestamps and Highlights : 00:00:01 – Introduction by Dave Asprey 00:02:00 – Dr. Zaki on Cynicism and Empathy 00:05:30 – The Science Behind Empathy and Human Goodness 00:10:00 – The Impact of Negativity Bias on Decision-Making 00:15:00 – How to Overcome Cynicism Through Skepticism 00:20:30 – Practices to Foster Empathy and Optimism 00:30:00 – Understanding Cynicism in the Digital Age 00:35:00 – Building Hope in Relationships and Society See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 3, 2024

In this special Asprey Archive episode from 2023, we talk to Shaahin Cheyene. Today’s guest is nothing short of a modern-day Willy Wonka for Generation X. He built a billion-dollar ecstasy business in the '90s and did not end up behind bars. That's a story you've got to hear. Shaahin Cheyene, not only dabbled in the wild world of herbal ecstasy but also managed to stay out of trouble despite being investigated by seven attorney generals. And get this, he wasn't even 18 when he pulled off these daring feats. Shaahin's story doesn't stop there. Since those days, he's become an Amazon expert, successfully selling nootropics and a variety of other products on the platform. He's also a filmmaker and author of the book, “Billion: How I Became the King of the Thrill Pill Cult.” From Fleeing Iran at the age of five to being homeless and living out of his car, Shaahin's journey is nothing short of remarkable. It's safe to say he's one of the most interesting individuals I've had the pleasure of interviewing. We dive into Shaahin's captivating journey, exploring his transformation from a young criminal to a thriving entrepreneur. You’ll also learn about what went into his groundbreaking herbal ecstasy formula and how he managed to get his business off the ground. Along the way, we discuss the challenges of navigating the bureaucracy of big government, the importance of seeking help when needed, and the valuable lessons Shaahin learned from building and eventually exiting his herbal ecstasy empire. We also delve into how he managed to run a nine-figure company selling on Amazon, the mindset benefits of Brazilian jiu-jitsu training, the power of curating ideas, and how you can strategically leverage podcasts as an entrepreneur. Join us on a ride you won't want to miss. (01:47) How Shaahin Became the King of the Thrill Pill Cult (07:36) Formulating Herbal Ecstasy & Building a Million-Dollar Business (16:34) Navigating the Bureaucracy of Big Government (28:04) Pro Tip for Entrepreneurs: Why It’s Important To Ask for Help (32:09) What Cheyene Learned From Building & Exiting His Business (37:29) What To Do When You Make Your First Million (39:21) Scaling a 9-Figure Company Selling on Amazon (45:05) Lessons From Martial Arts & Our Bets on Musk vs Zuckerberg (54:03) The Tactical Advantage of Podcasting & Being a Curator of Ideas (01:03:30) Media Training 101 Sponsors LMNT | Free LMNT Sample Pack with any drink mix purchase by going to https://drinklmnt.com/dave. Leela Quantum | Head to https://leelaq.com/DAVE for 10% off. Resources Website: shaahincheyenne.com PodcastCola: podcastcola.com Instagram: @shaahincheyene Podcast: Business Story of the Week LinkedIn: Shaahin Cheyene See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 29, 2024

In this episode of The Human Upgrade , vision expert Claudia Muehlenweg and strength coach Dave Mark Bell join Dave Asprey to explore the intersection of natural vision improvement and physical performance. Claudia shares her expertise in the Bates Method and techniques like palming, which help restore clarity and reduce eye strain. Dave Mark Bell highlights how physical training and focus can enhance not only strength but also vision, showing the deep connection between the body and mind. Check out the Full Episodes here: Claudia Muehlenweg: https://youtu.be/SpO6k9Ofh2E Dave Mark Bell: https://youtu.be/GV2KnL0wW9M Sponsors : Puori | Visit https://puori.com/dave and use code DAVE for 20% storewide. Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Resources : Naturally Clear Vision | Claudia Muehlenweg: https://www.youtube.com/@HolisticVisionCoach Dave Mark Bell’s Instagram: @marksmellybell Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ Timestamps and Highlights : 00:00:01 — Introduction by Dave Asprey 00:01:02 — Claudia Muehlenweg’s Introduction 00:03:30 — Palming and Its Benefits 00:06:15 — The Role of Eye Movement in Vision Health 00:09:25 — Dave Mark Bell’s Approach to Physical Training and Vision 00:12:45 — Sunlight and Vision 00:18:35 — Vision Improvement Techniques for Daily Life 00:22:50 — Vision and Fitness Synergy with Dave Mark Bell See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 27, 2024

In this enlightening episode of The Human Upgrade , Dave Asprey is joined by polymath and visionary Robert Edward Grant. Known for his groundbreaking work in fields ranging from mathematics and cryptography to art and consciousness, Robert shares insights into how his diverse expertise has shaped his understanding of the interconnectedness of science, art, and spirituality. The conversation delves into ancient knowledge, biohacking for personal evolution, and the deeper mysteries of consciousness, exploring how tapping into these realms can lead to profound innovation and a higher state of being. Sponsors : OneSkin | Go to https://oneskin.co/ and use code ASPREY15 for 15% off your purchase. Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Resources : Robert Grant’s Website: robertedwardgrant.com Follow Robert Grant on Instagram: @robertedwardgrant Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ Timestamps and Highlights : 00:00:01 — Introduction by Dave Asprey 00:02:05 — What It Means to Be a Polymath 00:05:34 — Innovation Through Cross-Disciplinary Thinking 00:08:26 — Consciousness and Psychedelics 00:13:22 — The Limits of Knowledge and Enlightenment 00:28:35 — The Path to Enlightenment 00:30:29 — The Benefits of Fasting for Mental and Physical Clarity 00:34:52 — The Power of Cold Therapy 00:38:23 — Overcoming Challenges in Biohacking See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 23, 2024

In this episode of The Human Upgrade , Dave Asprey is joined by Dr. Stephanie Venn-Watson, a veterinary epidemiologist and co-founder of Seraphina Therapeutics, to explore the groundbreaking discovery of C15, also known as Pentadecanoic acid. This episode uncovers how Dr. Venn-Watson's work with aging dolphins in the U.S. Navy led to the surprising revelation that C15 is an essential fatty acid, marking the first discovery of its kind in nearly a century. Through extensive research, C15 has shown powerful benefits for longevity, reducing inflammation, and promoting cellular health, which can help prevent chronic conditions like metabolic syndrome and heart disease. Dr. Venn-Watson explains the science behind C15, its natural sources—such as grass-fed dairy and certain types of fish—and why it’s often missing from modern low-fat diets. She also dives into the clinical studies that reveal how C15 can stabilize cell membranes, reduce oxidative stress, and improve metabolic function. The episode emphasizes the importance of this ‘new’ fat for anyone seeking to optimize their health, whether through diet or supplementation. Sponsors : Fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Resources : Dr. Stephanie Venn-Watson’s Company: Seraphina Therapeutics Dr. Stephanie Venn-Watson’s Instagram: @fatty15 Learn More About C15: discoverC15.com Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ Timestamps and Highlights : 00:00:01 — Introduction by Dave Asprey 00:01:02 — Dr. Stephanie Venn-Watson’s Introduction 00:03:15 — The Discovery of C15 00:05:56 — C15 in Fish and Dairy 00:08:03 — C15’s Role in Longevity and Cellular Health 00:12:35 — Clinical Studies and Health Benefits 00:20:12 — C15 and Vegan Diets See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 22, 2024

In this episode of The Human Upgrade , four experts—Dr. Molly Maloof, Aggie Lal, Dr. Justin Lehmiller, and Dr. Mary Claire Haver—discuss personalized biohacking strategies for women, focusing on hormonal balance, mitochondrial health, sexual wellness, and optimizing energy through cycle syncing and stress management. Dr. Molly Maloof , a health optimization expert and author, delves into the unique challenges women face in biohacking, focusing on mitochondrial health and the impact of hormonal fluctuations on energy and performance. She shares personalized strategies for optimizing health through nutrition, exercise, and stress management tailored to a woman’s biology. Aggie Lal , a certified health coach and biohacker, discusses the importance of balancing masculine and feminine energy for optimal health. She provides insights into cycle syncing, exercise, and lifestyle adjustments that empower women to harness their energy and enhance overall well-being. Dr. Justin Lehmiller , a social psychologist and researcher at the Kinsey Institute, explores the intersections of sexual health and biohacking, offering evidence-based insights into how sexual wellness impacts overall health. He discusses practical strategies for improving sexual relationships and boosting emotional and physical vitality through scientific research on sex and desire. Dr. Mary Claire Haver , an obstetrician and founder of The Galveston Diet, focuses on the challenges women face during menopause and midlife, providing expert guidance on nutrition and hormone balancing. She shares her evidence-based approach to supporting women through hormonal changes and optimizing health through targeted lifestyle interventions. Check out the Full Episodes here: Molly Maloof, MD https://www.youtube.com/watch?v=m9MkjHmQEfI&t=1577s Aggie Lal https://www.youtube.com/watch?v=2kizZSZT-As Justin Lehmiller, Ph.D. https://youtu.be/RS4VP07rKL0 Mary Claire Haver, MD https://www.youtube.com/watch?v=Ka-4YZUMQVE Timestamps and Highlights : 00:00:01 — Introduction by Dave Asprey 00:02:08 — Molly Maloof’s Journey 00:10:46 — Aggie Discusses Balancing Masculine and Feminine Energy 00:18:57 — Biohacking Your Menstrual Cycle 00:35:50 — Mitochondrial Health and Stress Management Sponsors : ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. Resources : Dr. Molly Maloof’s Website: https://drmolly.co Dr. Molly Maloof’s Instagram: @drmolly.co Aggie Lal’s “Biohack Like a Woman”: https://biohackingbestie.com/products/biohack-like-a-woman Biohacking Bestie: https://biohackingbestie.com/ Instagram: https://www.instagram.com/aggie/ Instagram: https://www.instagram.com/biohackingbestie/ TikTok: https://www.tiktok.com/@biohackingbestie Biohacking Bestie Podcast: https://biohackingbestie.com/pages/biohacking-bestie-podcast Dr. Justin Lehmiller’s Website: https://justinlehmiller.com Dr. Justin Lehmiller’s Instagram: @justinlehmiller Dr. Mary Claire Haver’s Website: https://galvestondiet.com Dr. Mary Claire Haver’s Instagram: @drmaryclaire Dave’s Linktree: linktr.ee/daveasprey Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 20, 2024

In this insightful episode of The Human Upgrade , Dave Asprey sits down with Dr. Mary Newport, a renowned expert in lipid metabolism and brain health, to discuss the critical role of fats in preventing Alzheimer's disease and promoting cognitive longevity. Dr. Newport, author of the book Clearly Keto for Healthy Brain Aging and Alzheimer’s Prevention , shares her deep knowledge of how different fats impact brain function, the benefits of ketogenic diets, and the connection between infections like herpes and Alzheimer’s disease. Learn about her personal journey caring for her husband, who was diagnosed with early-onset Alzheimer’s, and how ketogenic interventions, including coconut oil and MCT oil, led to significant improvements in his cognitive health. Tune in to learn more about the role of diet, ketones, and brain health, and how to make strategic food choices to maintain cognitive resilience as you age. Timestamps: 00:00:00 — Opening 00:01:07 — Introduction to Dr. Mary Newport and her work 00:02:29 — Clearly Keto: Overview of her new book 00:04:44 — Her husband’s Alzheimer’s journey 00:07:48 — Ketones and brain health 00:12:09 — Keto diets for brain function 00:24:00 — Insulin resistance and Alzheimer’s 00:44:00 — Alzheimer's research insights 01:01:18 — Final thoughts Sponsors: Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. Pendulum | Go to https://pendulumlife.com/ and use code Asprey20 for your first month of GLP-1 or any Pendulum formula. Resources: Website: http://coconutketones.com Facebook: Coconut Oil Helps Alzheimer’s, Dementia, ALS, MS https://www.facebook.com/CoconutOilandAlzheimers/ Twitter: https://twitter.com/marynewportmd LinkedIn: https://www.linkedin.com/in/mary-newport-md-226b3479/ Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Danger Coffee by Dave Asprey: https://dangercoffee.com/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 16, 2024

On this special Upgrade Spotlight episode of The Human Upgrade, you'll dive into the cutting-edge world of ketones and their profound impact on brain function and overall health with Michael Brandt, CEO and Co-founder of HVMN. Discover how Ketone IQ can fuel your cognitive abilities, enhance physical performance, and support your body's resilience under stress. Michael unpacks the science behind ketones, explaining how they improve mitochondrial efficiency, support fasting, and aid in recovery. He also shares innovative strategies to incorporate Ketone IQ into your daily routine, whether you're looking to boost your meditation practice, enhance athletic performance, or simply improve your metabolic flexibility. Tune in to uncover the latest advancements in ketone technology and learn how you can leverage them to optimize your health and performance. Timestamps: 00:00:00 — Opening 00:01:07 — Introduction to Ketones and the Episode's Focus 00:03:08 — Michael Brandt's Background 00:04:43 — Ketone IQ and Venture Capital 00:05:38 — The Science of Ketosis and Ketone IQ 00:10:27 — Ketone IQ vs. Other Ketone Supplements 00:19:24 — Ketones and Mitochondrial Function 00:22:02 — Practical Benefits of Ketone IQ 00:23:34 — Entrepreneurial Journey and Innovation 00:30:10 — Ketone IQ and Fasting 00:37:05 — Ketones, Cognition, and Special Operations 00:44:00 — Ketones and Brain Function 00:52:22 — Personal Fasting and Biohacking Experiences 00:57:05 — Ketone IQ in Sports and Olympics 01:01:18 — Ketone IQ and the Future of Biohacking 01:06:35 — Final Thoughts and Recommendations Sponsors: HVMN | Go to ketone.com/dave for 30% off your first subscription of Ketone IQ. Resources: Ketone IQ: ketone.com/dave for 30% off subscription HVMN: Follow on Instagram: @KetoneIQ Michael Brandt’s Instagram: @michaeldbrandt Dave's Linktree: https://linktr.ee/daveasprey Follow Dave on Instagram: @Dave.Asprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: [ https://daveasprey.com/books Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: ourupgradecollective.com Danger Coffee by Dave Asprey: @dangercoffeeofficial Supplements by Dave Asprey: shopsuppgradelabs.com Own an Upgrade Labs: ownanupgradelabs.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 15, 2024

In this special "Best Of" episode of The Human Upgrade , four leading experts delve into the hidden dangers of mold, environmental toxins, and their profound effects on your health and well-being. Brian Karr , an indoor environmental consultant and co-founder of We Inspect, discusses the impact of mold exposure and offers practical tips for detecting and remediating mold in your home. He highlights how mold can manifest in various symptoms and affect people differently. Michael Rubino , President of HomeCleanse, explores environmental toxins in our homes, highlighting the dangers of pollutants like formaldehyde and VOCs. Learn essential tips for maintaining clean air and creating a healthier living space to protect your health from mold and other toxins. Tune in for expert strategies on identifying and mitigating these risks. Dr. Francesca LeBlanc , a functional medicine expert, explains the connection between mold exposure, hormone imbalances, and weight gain. She shares insights on detoxing from mold and the importance of addressing underlying issues like estrogen dominance and candida. Dr. Neil Nathan , an environmental medicine expert and author of Toxic, explores the effects of mold toxicity on the immune system and provides strategies for protecting yourself from mold and other environmental toxins. CHECK OUT THE FULL EPISODES NOW! Brian Karr: https://www.youtube.com/watch?v=P_4UcEAZCEw&t=1760s Michael Rubino: https://www.youtube.com/watch?v=JFWcuWrEy60&t=73s Dr. Francesca LeBlanc: https://www.youtube.com/watch?v=_k3NGd-yfg8&t=1741s Dr. Neil Nathan: https://www.youtube.com/watch?v=eOEoQswppNc Timestamps: 00:00:01 - Introduction by Dave Asprey 00:02:08 - Dave's Personal Battle with Toxic Mold 00:03:06 - Understanding Mold with Brian Karr 00:10:40 - History of We Inspect and Mold Detection 00:18:57 - Mold in Rental Properties and Legal Challenges 00:23:17 - Practical Steps for Reducing Mold Exposure 00:35:50 - Dr. Francesca LeBlanc on Mold, Weight Gain, and Hormonal Imbalances 00:55:10 - The Role of Candida and Diet in Mold Recovery 01:00:22 - Dr. Neil Nathan on Mold Toxicity and Immune System Impact Sponsors: Puori | Visit Puori.com/DAVE and use the promo code DAVE for 20% storewide. ZBiotics | Go to Zbiotics.com/Dave for 15% off your first order Resources: Brian Karr’s Company: https://yesweinspect.com/ Brian Karr’s Instagram: @moldfinders Michael Rubino’s Linktree: https://linkin.bio/themichaelrubino/ Michael Rubino’s Instagram: @TheMichaelRubino Dr. Francesca LeBlanc’s Linktree: https://stan.store/drfrancescaleblanc Dr. LeBlanc’s Instagram: @drfrancescaleblanc Dr. Neil Nathan’s Books: https://neilnathanmd.com/about-me/ Dr. Neil Nathan’s website: https://neilnathanmd.com/ Dave’s Linktree: linktr.ee/daveasprey Follow Dave on Instagram: @Dave.Asprey Danger Coffee by Dave Asprey: Danger Coffee Instagram Supplements by Dave Asprey: Shop Upgrade Labs Own an Upgrade Labs: Own an Upgrade Labs See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 13, 2024

In this episode of The Human Upgrade, recorded live from Costa Rica, Dave Asprey sits down with Dr. Vince from the Regenerative Medicine Institute (RMI) to delve into the groundbreaking world of regenerative medicine. Dr. Vince shares his expertise on how advanced therapies, including stem cell treatments and personalized regenerative protocols, are paving the way for enhanced longevity and optimal health. Listeners will gain insight into how these cutting-edge treatments can address chronic pain, accelerate recovery, and combat aging at the cellular level. Dr. Vince also emphasizes the importance of personalized medicine, where treatments are tailored to each individual's unique biological needs. This episode is a must-listen for anyone interested in exploring the future of regenerative health and how to apply these innovations to improve their own healthspan and lifespan. Timestamps: 00:00:01 — Opening 00:02:44 — Introduction to Dr. Vincent Giampapa 00:05:50 — Dr. Giampapa’s Morning Cognitive Enhancement Protocol 00:09:23 — The Role of Brain Imaging in Personalized Medicine 00:13:09 — Stem Cell Therapy: The New Frontier in Longevity 00:19:29 — The Importance of Banking Stem Cells for Future Use 00:32:35 — Groundbreaking Anti-Aging Treatments at RMI 00:42:43 — Focused Ultrasound and Reprogramming the Hypothalamus 00:50:16 — The Role of Peptides in Muscle Growth and Cognitive Function 01:06:42 — How to Get Started with Longevity Treatments 01:12:24 — Ethical Considerations in Longevity Science 01:23:47 — Future of Gene Therapy and Mitochondrial Enhancement 01:30:02 — Final Thoughts and Closing Remarks Sponsors: Quantum Upgrade | Go to QuantumUpgrade.io/Dave for a free trial Timeline Nutrition | Head to TimelineNutrition.com/Dave to get 10% off your first order. Resources: Inquire about RMI Treatment: https://daveasprey.com/clock/ Learn more about RMI: https://rmi.life/Dave Follow Dr. Giampapa on Instagram: @drgiampapa Dr. Giampapa’s website: https://drgiampapa.org/ Dave's Linktree: linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: ourupgradecollective.com Danger Coffee by Dave Asprey: @dangercoffeeofficial Supplements by Dave Asprey: shopsuppgradelabs.com Own an Upgrade Labs: ownanupgradelabs.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 8, 2024

In this special "Best Of" episode of The Human Upgrade , four leading experts share their insights on skincare, skin health, and cutting-edge techniques to enhance your appearance and overall well-being. Rachel Varga , a Board-Certified Aesthetic Nurse Specialist and recognized expert in skin rejuvenation, discusses the importance of biohacking for maintaining vibrant, healthy skin. She highlights key strategies, including air and water purification, regular detoxification, and the careful selection of skincare products free from harmful chemicals. Dr. Anthony Youn , a Board-Certified Plastic Surgeon and bestselling author, reveals the most common skincare mistakes made by both men and women. He provides actionable advice on avoiding harmful practices like over-exfoliation and improper sunscreen use, while also emphasizing the critical role of diet in achieving glowing, youthful skin. Dr. Nayan Patel , a global expert in glutathione research and author of The Glutathione Revolution , explains the essential role of glutathione in detoxification and cellular health. He shares insights into the most effective methods for glutathione supplementation and the latest advancements in personalized health testing. Dr. Rob Whitfield , a Board-Certified Plastic Surgeon and founder of the Austin area's premier aesthetic clinic, explores the latest non-invasive procedures for skin tightening and rejuvenation. He compares various technologies, including IPL, lasers, and SoftWave, and discusses the innovative “No Cut Facelift” technique for achieving long-lasting results without surgery. Tune in to this episode to learn expert strategies for optimizing your skincare routine and enhancing your skin’s health and appearance from top professionals in their field. CHECK OUT THE FULL EPISODES NOW! Rachel Varga: https://www.youtube.com/watch?v=J9b7i6nOwpI&t=1899s Dr. Anthony Youn: https://www.youtube.com/watch?v=gGcpW0_KAIU&t=2588s Dr. Nayan Patel: https://www.youtube.com/watch?v=H2j23OdO-1E Dr. Rob Whitfield: https://www.youtube.com/watch?v=leFjhLWQBqo Timestamps: 00:00:01 - Introduction by Dave Asprey 00:00:10 - The Importance of Skin Health and Biohacking Techniques 00:05:03 - Harmful Ingredients in Skincare Products 00:09:00 - Core Biohacking Strategies for Healthy Skin 00:14:10 - Men’s Skincare Mistakes: Bar Soap and Over-Exfoliation 00:18:50 - Understanding Sunscreen: Chemical vs. Physical 00:23:35 - Women’s Skincare Pitfalls: Overuse of Products and Procedures 00:27:50 - The Role of Glutathione in Detoxification and Health 00:32:45 - Innovations in Glutathione Testing and Personalized Health 00:36:30 - Non-Invasive Skin Tightening with SoftWave 00:42:15 - Comparing Skin Rejuvenation Techniques: IPL, Lasers, and More Sponsors: Fatty15 | Go to Fatty15.com and save an extra $15 when you subscribe with code DAVE. LMNT | Free LMNT Sample Pack with any drink mix purchase by going to DrinkLMNT.com/Dave Resources: Rachel Varga’s Linktree: https://linktr.ee/rachelvargaofficial Follow Rachel on Instagram: @RachelVargaOfficial Dr. Anthony Youn’s Linktree: https://taplink.cc/tonyyounmd Dr. Anthony Youn’s Instagram: @TonyYounMD Auro Wellness on Instagram: @AuroWellness Dr. Rob Whitfield’s Linktree: https://linktr.ee/drrobertwhitfield Follow Dr. Rob on Instagram : @ breastimplantillnessexpert Dave’s Linktree: linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: Link to book Follow Dave on Instagram: @Dave.Asprey Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: ourupgradecollective.com Danger Coffee by Dave Asprey: Danger Coffee Instagram Supplements by Dave Asprey: shopsuppgradelabs.com Own an Upgrade Labs: ownanupgradelabs.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 6, 2024

In this episode of The Human Upgrade, Dr. Manoj Doss, a neuroscientist at the University of Texas at Austin Dell Medical School, explores the fascinating intersection of psychedelics, memory, and cognitive enhancement. Drawing from his extensive research, Dr. Doss dives into how psychoactive substances like THC, ketamine, and psychedelics can alter memory formation, consolidation, and retrieval. He challenges the conventional understanding of memory by revealing how these substances might disrupt traditional memory processes while potentially opening new pathways for learning and cognition. You'll discover how different drugs impact your brain's ability to encode and recall information, the surprising effects of psychedelics on semantic and episodic memory, and the role of the hippocampus in shaping our personal narratives. Dr. Doss also delves into the potential benefits and risks of cognitive enhancers like nicotine and modafinil, offering insights into their effects on memory and brain function. Dr. Doss provides a nuanced perspective on the malleability of memory, the ethical implications of memory manipulation, and the complex relationship between trauma, memory, and psychedelics. This episode is essential for anyone interested in the cutting-edge science of memory, the therapeutic potential of psychedelics, and the quest to enhance cognitive performance. Timestamps: 00:00:01 — Opening 00:01:39 — Introduction to Dr. Manoj Doss 00:03:20 — The Impact of Psychedelics on Memory 00:05:50 — The Predictive Processing Framework and Mind Models 00:13:22 — Alcohol and Retrograde Facilitation: Enhancing Memory Post-Study 00:19:00 — Differences Between Episodic and Semantic Memory 00:22:57 — The Role of the Hippocampus in Memory Formation 00:32:35 — Exercise, BDNF, and Memory Enhancement 00:42:29 — The Complex Relationship Between Psychedelics and Neurogenesis 00:52:16 — The Fallibility of Memory and False Memory Formation 01:09:04 — The Influence of Nicotine, Modafinil, and Other Cognitive Enhancers 01:30:34 — Closing Remarks Sponsors: ARMRA | Go to TryARMRA.com and use the code DAVE to get 15% off your first order. Leela Quantum | Head to LeelaQ.com/Dave for 10% off. Resources: Follow Dr. Manoj Doss on Twitter Dave's Linktree: https://linktr.ee/daveasprey Follow Dave on Instagram: @Dave.Asprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 1, 2024

In this episode of The Human Upgrade , Dr. Christy Sutton delves into the intricate relationship between iron, zinc, copper, and other essential minerals that play a crucial role in longevity and overall health. Drawing from her book, The Iron Curse , Dr. Sutton shares insights into how mineral imbalances can lead to conditions like iron overload, anemia, and other health issues, and how these imbalances affect the body’s ability to function optimally. You'll learn about the significance of monitoring and managing your mineral levels, the impact of iron on cognitive function and aging, and the genetic factors that influence mineral absorption. Dr. Sutton also discusses the importance of personalized nutrition and supplementation in maintaining optimal health and preventing disease. Dr. Sutton provides practical advice on how to recognize symptoms of mineral imbalances, the importance of regular lab testing, and the role of diet and lifestyle in managing these conditions. This episode is a must-listen for anyone interested in taking control of their health and longevity by understanding the foundational role of minerals in the body. Timestamps: 00:00:01 — Opening 00:02:44 — Introduction to Dr. Christy Sutton 00:05:50 — Iron Levels and Longevity 00:13:09 — Recognizing the Symptoms of High Iron 00:19:29 — Iron Levels in Children and the Risk of Misdiagnosis 00:32:35 — Managing High Iron through Diet and Supplementation 00:42:43 — Key Labs to Monitor for Iron and Mineral Levels 00:50:16 — The Role of Copper in Iron Absorption 01:06:42 — Closing Remarks Sponsors: Calroy | Head to Calroy.com/Dave for an exclusive discount. Viome | Go to Viome.com/Dave to save $110 on the Full Body Intelligence Test. Resources: Buy Dr. Christy’s book: The Iron Curse Dr. Christy Sutton's Linktree: https://linktr.ee/drchristysutton Follow Dr. Christy on Instagram: https://www.instagram.com/drchristysutton/ Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 30, 2024

In this episode of The Human Upgrade, renowned opera singer Renée Fleming explores the powerful connection between music, neuroscience, and longevity. Renée shares her journey with stage fright and somatic pain, revealing how she overcame these challenges to achieve greatness in her field. You'll learn about the impact of music on the brain, its role in enhancing cognitive function, and its potential to delay dementia. Renée discusses functional MRI studies, the benefits of group singing, and the integration of music into healthcare. Renée also shares practical tips on maintaining vocal health and immunity, the healing power of nature, and the importance of artistic practices in childhood development. This episode is for anyone who wants to understand the transformative power of music and its potential to enhance brain health, emotional well-being, and overall longevity. Timestamps: (00:00:00) Opening (00:01:56) Renée Fleming's Journey with Music and Neuroscience (00:05:25) The Experience of Stage Fright: Physical and Mental Aspects (00:12:24) The Power of Imagining Singing (00:14:18) Impact of Music on the Brain: A Broader Perspective (00:16:32) Breathwork and Singing's Benefits on the Nervous System (00:18:33) Music’s Role in Delaying Dementia (00:26:26) The Benefits of Group Singing (00:29:59) The Synchronization of Brainwaves and Heart Rates (00:31:08) The Impact of Artistic Practices on Children (00:36:12) The Importance of Nourishing the Soul with the Arts (00:42:47) The Intersection of Psychedelics and Music (00:50:23) Advances in Sound Therapy for Health (00:54:35) Renée’s Personal Practices and Preferences (00:56:10) Closing Thoughts and Reflections Sponsors Timeline | Go to Timeline.com/Dave to get 10% off your first order. Zbiotics | Head to Zbiotics.com/dave for 15% off your first order. Resources Renee Fleming Linktree: https://linktr.ee/reneeflemingmusic Follow Renee Fleming on Instagram: @ReneeFlemingMusic Buy Ms. Fleming’s new book “ Music and Mind ” now! Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 25, 2024

In this episode of The Human Upgrade, Dr. Tracy Gapin, a board-certified urologist, men's health expert, and founder of the GAPIN Institute, discusses the critical role of testosterone in health. He addresses the alarming decline in testosterone levels globally, the symptoms of low testosterone, and its impact on male behavior. You'll gain insights into natural methods to boost testosterone, the challenges of maintaining optimal levels, and the pros and cons of Testosterone Replacement Therapy (TRT). Dr. Tracy explains the role of estrogen and DHT in health and highlights the effects of testosterone on brain function, motivation, and cardiovascular health. You’ll learn about the adverse effects of environmental toxins on testosterone, effective delivery methods, and the importance of personalized treatment plans. Dr. Gapin also covers practical tips for reducing exposure to environmental toxins, balancing work, life, and health, and the significance of sleep and recovery. Timestamps: 00:00:00 - Introduction to Dr. Tracy Gapin and Testosterone Discussion 00:02:00 - The Importance of Measuring Free Testosterone 00:03:43 - Symptoms and Impact of Low Testosterone 00:06:23 - Natural Ways to Boost Testosterone 00:09:59 - Testosterone Replacement Therapy (TRT) Options 00:15:18 - Health Benefits and Brain Function of Optimized Testosterone Levels 00:17:48 - Environmental Toxins and Declining Fertility Rates 00:25:57 - Effective Testosterone Delivery Methods 00:29:47 - Overtraining and Its Impact on Hormones 00:42:51 - Microplastics and Their Impact on Health 00:53:40 - Comprehensive Health Assessments at the GAPIN Institute 01:02:57 - Balancing Work, Life, and Health 01:13:26 - Practical Tips for Avoiding Environmental Toxins 01:27:26 - The Importance of Sleep and Recovery 01:38:36 - Conclusion and Final Thoughts Sponsors: Our Place | Head to FromOurPlace.com and use the code DAVE for 10% off your order. Fatty 15 | Go to Fatty15.com and save an extra $15 when you subscribe with the code DAVE15. Resources: Check out the Gapin Institute: https://gapininstitute.com/upgrade Gapin Institute Linktree: https://linktr.ee/gapininstitute Follow Dr. Tracy on Instagram: @DrTracyGapin Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 23, 2024

In this special episode of The Human Upgrade , you will gain insights from four experts on brain health, memory, attention, and cognitive enhancement. Dr. Daniel Amen , a renowned psychiatrist and brain health expert, discusses the importance of daily practices for brain and mental health. He shares strategies to improve brain function and prevent cognitive decline. Jim Kwik , a brain coach and memory expert, talks about physical and mental exercises that boost brain performance. He offers tips on how to improve reading, memory, and focus, and highlights the benefits of both fiction and nonfiction reading. Dr. Adam Gazzaley , a neuroscientist and professor, explains the difference between top-down and bottom-up attention. He introduces Endeavor Rx, a video game approved by the FDA to improve attention in children with ADHD and shares how it can benefit adults as well. Dr. Patrick Porter , an expert in brain fitness and neurogenesis, discusses the BrainTap technology. He explains how it can enhance cognitive function, reduce stress, and improve sleep through guided meditation and light therapy. Tune in to this episode to learn practical tips and expert advice on optimizing brain health, improving memory, and enhancing attention for better cognitive performance. CHECK OUT THE FULL EPISODES NOW! Dr. Daniel Amen: https://youtu.be/ri7-Ou6VvSI Jim Kwik: https://youtu.be/QCt2XHJkt2Y Dr. Adam Gazzaley: https://youtu.be/H9QT7bKFgmM Dr. Patrick Porter: https://youtu.be/o8B4XrueQlc Timestamps : 00:00:07 - Introduction by Dave Asprey 00:00:10 - Dr. Daniel Amen on Brain Health Practices 00:10:04 - Jim Kwik on Physical and Mental Exercise 00:12:28 - Jim Kwik on Reading and Brain Exercises 00:18:22 - Jim Kwik on Sleep and Productivity 00:30:26 - Dr. Adam Gazzaley on Top-Down vs Bottom-Up Attention 00:40:02 - Dr. Adam Gazzaley on Endeavor Rx and Attention Improvement 00:46:51 - Dr. Patrick Porter on Neurogenesis and Brain Fitness 00:58:51 - Dr. Patrick Porter on BrainTap and Cognitive Enhancement Sponsors : Fatty15 | Go to Fatty15.com and save an extra 15$ when you subscribe with code DAVE15. Our Place | Go to FromOurPlace.com and use code DAVE for 10% off your order. Resources: Dr. Daneil Amen’s Website: https://danielamenmd.com/ Dr. Daniel Amen’s Instagram: @Doc_Amen Jim Kwik’s Instagram: @JimKwik Jim Kwik’s Linktree: https://linktr.ee/kwiklearning Dr. Adam Gazzaley’s Instagram: @adamgazzaley Dr. Adam Gazzaley’s website: https://gazzaley.com/ BrainTap’s Instagram: @BrainTapTech BrainTap’s Linktree: https://linktr.ee/braintap Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 19, 2024

On this special Upgrade Spotlight episode of The Human Upgrade, you'll explore the science of NAD and its vital role in your cellular health with Dr. Nichola Conlon from Nuchido Laboratories. Learn how NAD supports energy production, cellular repair, and longevity. Dr. Conlon breaks down the latest research on NAD, explaining why levels decline with age and how to naturally boost them without expensive and uncomfortable IV treatments. Dr. Conlon breaks down innovative ways to enhance your NAD levels, reduce inflammation, and improve overall health and shares practical tips on maintaining high NAD levels through diet, lifestyle changes, and supplementation. You’ll understand how these strategies can combat fatigue, brain fog, and aging symptoms, offering benefits for both physical and cognitive performance. Tune in to uncover the latest advancements in NAD research and how you can apply them to enhance your cellular health and well-being. Timestamps: 00:00:00 — 1: Opening 00:01:07 — 2: Introduction to NAD and Dr. Nichola Conlon 00:01:46 — 3: Understanding NAD and Its Functions 00:02:23 — 4: The Challenges of Boosting NAD Levels 00:05:31 — 5: The Science Behind NAD Decline and Aging 00:09:15 — 6: Clinical Studies and Evidence 00:14:35 — 7: Practical Benefits of Boosting NAD 00:19:17 — 8: Addressing Inflammation and Glycation 00:26:32 — 10: Big Pharma vs. Supplement Approach 00:30:10 — 11: Enhancing Bioavailability of Supplements 00:33:45 — 12: Impact on Chronic Conditions 00:37:05 — 13: Addressing Autoimmunity and Inflammation 00:44:00 — 15: Final Thoughts and Recommendations Sponsors: Nuchido | Go to Nuchido.com/Upgrade, or use code Upgrade10, for a 10% discount! Resources: Nuchido.com/Upgrade, or use code Upgrade10, for a 10% discount! Follow Nuchido on Instagram: @Nuchido Nuchido’s Linktree: https://linkin.bio/nuchido/ Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 18, 2024

In this special episode of The Human Upgrade , you will gain insights from four fitness and health experts on understanding muscle, how to grow muscle, exercise effectively, and recover properly. Dr. Gabrielle Lyon , a functional medicine physician, emphasizes the critical role of skeletal muscle as an organ of longevity. She explains how muscle health impacts overall well-being and offers strategies to prevent age-related muscle loss. John Jaquish , the inventor of the X3 bar, discusses the benefits of variable resistance training. He shares his expertise on progressive overload and how data-driven training can enhance muscle growth and performance. Tony Horton , the creator of P90X, introduces the concept of muscle confusion. He explains how varying workout routines can prevent plateaus, reduce injuries, and keep your fitness journey exciting and effective. Magnus Lygdbäck , a celebrity trainer, provides tips on optimizing performance and recovery. He highlights the importance of structured habits, balanced nutrition, and recovery techniques like ice baths and isometric exercises to sustain high performance. Tune in to this episode to learn practical tips and expert advice on building muscle, improving exercise routines, and optimizing recovery for long-term health and fitness. CHECK OUT THE FULL EPISODES NOW! Dr. Gabrielle Lyon: https://youtu.be/X3hkW0afys0 John Jaquish: https://youtu.be/6efQiP_rCLM Tony Horton: https://youtu.be/BRSvTx8Ank4 Magnus Lygdbäck: https://youtu.be/9x3fvChVwyo Timestamps: 00:00:00 — Opening 00:00:10 — Dr. Gabrielle Lyon on Skeletal Muscle Health 00:02:32 — Aging and Muscle 00:06:03 — Measuring Muscle Quality 00:09:15 — Genetic Potential 00:20:41 — John Jaquish on Variable Resistance Training 00:24:32 — Progressive Overload 00:27:37 — Neurological Adaptation 00:31:47 — Data-Driven Training 00:34:39 — One Meal a Day and Protein 00:44:15 — Tony Horton on Muscle Confusion 00:47:45 — Using Bands for Resistance 00:50:16 — Continuous Training 00:52:03 — Balancing Rest and Work 00:54:27 — Magnus Lygdbäck on Optimizing Performance 00:57:15 — Nutrition vs. Training 01:00:15 — Avoiding Perfectionism 01:02:48 — Pre-Performance Training 01:05:59 — Blood Flow Restriction Sponsors: Calroy | Head over to Calroy.com/Dave for an exclusive discount LMNT | Get a free LMNT Sample Pack with any drink mix purchase by going to DrinkLMNT.com/Dave Resources: Dr. Gabrielle Lyon's Website: https://drgabriellelyon.com/ Dr. Gabrielle Lyon’s Instagram: @drgabriellelyon Order Dr. Gabrielle Lyon’s Book: Forever Strong John Jaquish's X3 Bar: https://www.jaquishbiomedical.com/ Dr. John Jaquish’s Instagram: @drjaquish Tony Horton's Programs: https://www.tonyhortonlife.com/ Tony Horton’s Instagram: @TonySHorton Magnus Lygdbäck’s Instagram: @magnuslygdback Magnus Lygdbäck's Training: https://www.magnusmethod.com/ Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 16, 2024

In this episode of The Human Upgrade , entrepreneur and philanthropist Naveen Jain discusses groundbreaking insights into the differences between oral and gut microbiomes and the impact of oral bacteria on overall health. You’ll learn why traditional mouthwash might be harmful and explore the Apollo Group's role in health mentoring and collaboration. Naveen shares his decade-long dedication to solving health issues and his approach to large-scale health problems. You’ll discover the relationship between oral microbiomes and digestion, the dangers of artificial sweeteners, and the importance of personalized nutrition. Naveen emphasizes the need for cycling low-carb and keto diets, and the risks of long-term adherence. He also highlights the significance of quality sleep, personalized exercise, and the impact of stress on microbiome health. Tune in for practical tips on maintaining a healthy microbiome and the importance of living with purpose for longevity. Timestamps: 00:00:00 — Introduction 00:01:02 — Oral Bacteria vs. Gut Bacteria 00:05:30 — Oral Microbiome and Digestion 00:09:00 — Low Carb and Keto Diet Misconceptions 00:12:23 — Red Meat and Microbiome 00:14:49 — Impact of Vegetables on Gut Health 00:23:02 — DNA vs. RNA in Health 00:30:56 — Debunking Blood Type Diets 00:31:57 — Lipopolysaccharides and Inflammation 00:40:07 — Importance of Oral Microbiome 00:50:28 — Practical Microbiome Health Tips 01:05:22 — Exercise and Microbiome 01:14:03 — Managing Stress for Health 01:22:18 — Purpose and Longevity Sponsors: Viome.com | Viome.com/Dave to save $110 on the Full Body Intelligence Test. Timeline Nutrition | Go to TimelineNutrition.com/Dave to get 10% off your first order. Leela Quantum | Visit LeelaQ.com/Dave for 10% off. Resources: Follow Naveen Jain on Instagram: @naveenjainceo Naveen Jain Linkedin: https://www.linkedin.com/in/naveenjainintelius/ Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 11, 2024

In this episode of The Human Upgrade, Dr. Robert Lufkin delves into the misconceptions in medical education and the vital importance of metabolic health. He discusses how outdated practices in medical training can negatively impact public health and shares insights on the critical role of personalized nutrition in enhancing metabolic health. Dr. Lufkin explores the connection between hormones and aging, highlighting new therapies that target hormonal balance. He also explains the paradigm shift in health, emphasizing the need to move beyond conventional wisdom and integrate new scientific research into everyday practice. You will learn about the latest advances in medical technology and how tech-driven interventions can extend HealthSpan. Dr. Lufkin also addresses the challenge of overcoming medical dogmas, stressing the importance of continuous learning and adaptation in the medical field. Tune in to discover emerging trends in personalized medicine, the future of healthcare, and practical strategies for improving health and longevity. This episode offers valuable knowledge and actionable advice for navigating the evolving landscape of modern medicine. Timestamps: (00:01:03) Introduction to Dr. Robert Lufkin (00:04:51) Misconceptions in Medical Education (00:12:27) Metabolic Health and Diet (00:16:32) Hormones and Aging (00:21:10) The Paradigm Shift in Health (00:29:17) The Role of Technology in Longevity (00:33:27) Extending Healthspan (00:40:54) Future of Medicine (01:00:32) Intermittent Fasting Benefits (01:10:15) The Role of Exercise in Longevity (01:20:12) Nutritional Supplements (01:30:18) Advancements in Anti-Aging Therapies (01:45:22) Closing Thoughts Sponsors: Neurohacker | Go to Neurohacker.com and use code Dave for 15% off. Quantum Upgrade | Head to QuantumUpgrade.IO/Dave for a free trial. Resources: Dr. Robert Lufkin’s new book “ The Sensitive Patient's Healing Guide ” is out now! Learn more about Dr. Robert Lufkin’s work: RobertLufkinMD.com Follow Dr. Lufkin on Instagram: @robertlufkinmd Dr. Lufkin’s Linktree: https://linktr.ee/robertlufkinmd Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 9, 2024

In this episode of The Human Upgrade, Dr. Peter Ballerstedt, a leading expert in ruminant animal agriculture, discusses the essential role of ruminant animals in sustainable farming. You'll learn about the critical importance of animals like cows and sheep in maintaining soil health, supporting ecosystems, and providing high-quality nutrition. You’ll also learn about the myths surrounding livestock emissions and how regenerative farming practices benefit both the environment and human health. Dr. Ballerstedt explains the complexities of modern agriculture, emphasizing the importance of metabolic health and the significant impact of dietary choices on global food security. You'll gain insights into the health benefits of animal protein, crucial for preventing malnutrition and supporting overall well-being, and how integrating crop and livestock systems can enhance food production and sustainability. Tune in for valuable knowledge and practical advice on improving health and supporting sustainable agriculture through the inclusion of ruminant animals. Timestamps: (00:01:03) What are Ruminant Animals? (00:03:27) The Importance of Ruminant Animals in Agriculture (00:05:09) The Environmental Impact of Ruminant Animals (00:17:24) Addressing Common Misconceptions (00:35:31) Sustainable Food Systems and Global Food Security (00:40:53) The Health Benefits of Animal Protein (00:57:15) The Importance of Metabolic Health Sponsors ARMRA | Go to TryARMRA.com and use code DAVE for 15% off your first order. Resources Follow Peter Ballerstedt on Instagram: @GrassBased Twitter: @GrassBased Peter’s Substack: https://ruminati.substack.com/ Peter’s blog: https://grassbasedhealth.blogspot.com/ Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 4, 2024

In this special Asprey Archive episode of The Human Upgrade you’ll get tips about how to lead a brain healthy lifestyle and how to keep perspective along your own entrepreneurial journey. Activism, acting and entrepreneurship are wired into Patrick Schwarzenegger’s DNA. In this episode from 2022, he thoughtfully balances each passion through his work as an Alzheimer’s advocate, actor, investor and food founder. Patrick’s known for his trend-spotting abilities in the better-for-you food and beverage industry. He got into the fast-casual Blaze Pizza franchise when he was just a teen. That experience solidified his interest in health and wellness: “invest solely into entrepreneurs and companies that were providing Americans with the healthier alternative." He’s now an active investor and advisor to numerous brands and helps founders scale their emerging businesses to the next level. His latest venture encourages brain health at every age and supports programs, research, and lifestyle choices designed to make your brain work better. Patrick co-founded a brain health food brand called “ MOSH ” with his mom, Maria Shriver , designed specifically to up-level your brain function. A journey with its share of mishaps, too: “We had so many things that went wrong and that was kind of the fun part was learning about that and finding ways to fix it. That's wanting to be an entrepreneur or that's embarking on that journey, you're going to have speed bumps. You can do as much homework as you can and want and try to perfect everything before you launch, but things come out of left field every single day.” He’s on the show to discuss entrepreneurship, how to invest, how to build brands, how to hire the right people and what’s possible for high-functioning brains at every age. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 2, 2024

In this episode of The Human Upgrade, Harry Massey joins the show to delve into the fascinating field of bioenergetics and its profound impact on health and healing. Discover how bioenergetics, the study of energy in living systems, can revolutionize your approach to wellness by enhancing the body's energy and control systems. Harry shares his journey from battling chronic fatigue syndrome to founding NES Health, where cutting-edge research and technology are used to enhance cellular function and resilience. You'll learn about the role of mitochondria, structured water, and light in boosting the body's energy and efficiency. The conversation also explores how bioenergetics can help reframe our understanding of health by integrating principles from physics, chemistry, and biology. You’ll also gain insights into the practical applications of bioenergetics, including NES Health's innovative voice scan technology that provides personalized health insights. Harry and Dave discuss the future of energy-based treatments and the importance of a strong energetic control system in maintaining the best health possible. Get ready to upgrade your understanding of health with actionable advice and scientific insights from two pioneers in the field! Timestamped Highlights (00:01:10) Harry Massey's background and journey through chronic fatigue syndrome. (00:02:16) Definition and principles of bioenergetics. (00:03:36) Charging the body’s energy and the role of structured water. (00:08:20) Efficiency of the energetic control system vs. chemical control system. (00:12:35) Impact of light and structured water on mitochondria. (00:18:26) Research on structured water and its effects on cellular health. (00:22:02) Increasing mitochondrial density and resilience. (00:26:15) Harry's personal health journey and the development of NES Health. (00:30:16) Comparison with homeopathy and the concept of information in water. (00:35:06) Overcoming skepticism and proving the effectiveness of bioenergetics. (00:42:46) Real-life examples of bioenergetic healing. (00:50:09) The impact of emotions on health and the importance of positive energy. (00:54:30) Enhancing resilience and protecting against negative influences. (01:01:09) Introduction to NES Health's voice scan technology. (01:05:53) Using voice analysis for health insights and personal coaching. Sponsors NES Health: Go to neshealth.com/Dave for your free voice scan! Viome | Go to Viome.com/Dave to save $110 on the Full Body Intelligence Test. Apollo Neuro | Head to ApolloNeuro.com/DaveAsprey to save 15% on an Apollo wearable. Quantum Upgrade | Go to Quantum Upgrade.io/Dave for a free trial. Resources: NES Health: Go to neshealth.com/Dave for your free voice scan Energy4Life: energy4life.com Follow NES Health on Instagram: @NES.Health Get Tickets to the Zenergy Conference: zenergyconference.com Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 27, 2024

In this episode of The Human Upgrade, Dr. Neil Nathan joins to explore the intricate world of toxic mold, Lyme disease, and sensitivity-related illnesses. You'll discover the profound impact of these environmental toxins on your health and the innovative methods for diagnosing and treating them. Learn how mold and Lyme disease can disrupt your body's systems, and get practical strategies for protecting yourself from these hidden hazards. The discussion dives into the importance of the limbic and vagal systems, and how rebooting them can help manage sensitivity and promote healing. Dr. Nathan sheds light on the role of environmental pollution in exacerbating mold issues and offers tips for reducing your exposure to harmful toxins. You'll gain a deeper understanding of how to maintain resilience and enhance your health despite these challenges. Tune in to gain valuable insights and actionable advice on managing sensitivity and reclaiming your health from environmental toxins! Timestamps and Highlights: (00:00:01) Introduction (00:03:03) Mold Rage and Personality Changes (00:05:02) Understanding Mold Toxicity (00:09:04) Symptoms and Misdiagnosis (00:11:46) Environmental Factors and Increased Mold Toxicity (00:15:40) Practical Steps for Protection (00:19:35) Testing and Treating Mold Toxicity (00:25:26) Limbic and Vagal System Retraining (00:29:26) Personal Healing Practices (00:33:31) The Role of Intuition in Healing (00:39:31) Addressing Chronic Illness and Sensitivity (00:45:41) Emotional and Psychological Aspects of Healing (00:50:16) Conclusion Sponsors: Timeline Nutrition | Go to TimelineNutrition.com/Dave to get 10% off your first order. Beam Minerals | Go to BeamMinerals.com/Dave2024 for 20% off your first order Resources: Dr. Neil Nathan’s new book “ The Sensitive Patient's Healing Guide ” is out now! Learn more about Dr. Neil Nathan’s work: NeilNathanMD.com Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 25, 2024

In this episode of The Human Upgrade, Dr. John Gildea and David Roberts from BrocElite join to discuss the powerful benefits of sulforaphane and NRF2 activation. You'll hear about the science behind sulforaphane, a potent compound in broccoli, and how it can boost your health by protecting your cells and enhancing detoxification. Learn why eating broccoli and broccoli sprouts can be a game-changer for your diet and get practical tips on how to incorporate them into your meals. The discussion highlights the role of sulforaphane in supporting gut health and improving resilience to toxins. Dr. Gildea and David Roberts explain the importance of NRF2 activation in promoting longevity and better performance. You'll understand how these mechanisms work to keep your body functioning optimally and how you can leverage them for better health. Tune in to gain valuable insights and actionable advice on enhancing your health with sulforaphane and NRF2 activation! Timestamp Highlights: (00:00:00) Introduction: Benefits of sulforaphane and NRF2 activation. (00:01:04) Are Bodybuilders the Edgiest Biohackers? (00:02:10) Benefits of Broccoli and Sulforaphane (00:04:23) Isothiocyanates and Thyroid Function (00:10:57) Longevity and Performance Impacts of NRF2 (00:18:20) Resilience Against Toxins (00:24:57) Sulforaphane and Autism (00:31:08) Anti-Inflammatory Effects of Sulforaphane (00:40:52) Gut Health and Microbiome (00:45:58) Autophagy and Cellular Health (00:55:57) Dosage and Safety (01:02:00) Closing Thoughts Sponsors: Go to Mara-Labs.com/Dave and save up to 28% off your order. Our Place | Go to FromOurPlace.com and use the code DAVE for 10% off your order. ZBiotics | Go to Zbiotics.com/Dave for 15% off your first order. Resources: Go to Mara-Labs.com/Dave and save up to 28% off your order. Follow Mara Labs on Instagram: @themaralabs Twitter: @TheMaraLabs Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 20, 2024

In this episode of The Human Upgrade - Max Lugavere, a journalist and filmmaker, joins to discuss his new documentary "Little Empty Boxes." Max shares his personal story of dealing with his mother's dementia, offering a unique and heartfelt perspective on this challenging condition. You’ll learn about the significant role diet and lifestyle play in keeping your brain healthy and how you can lower your risk of developing dementia through simple, everyday actions. Max also shares the latest research on dementia, shedding light on the science behind prevention and early intervention. He explains why it's crucial to start taking care of your brain health now, regardless of your age. Additionally, you’ll hear about the emotional impact of dementia on families and practical ways to support loved ones going through it. Tune in to gain valuable insights and actionable tips on how to protect your brain health and help others do the same. This episode is packed with practical advice that you can start applying today to make a real difference in your cognitive health and overall well-being. Timestamp Highlights: (00:01:04) Introduction: Max Lugavere’s personal connection to dementia. (00:04:51) The creation of "Little Empty Boxes" and its focus on dementia prevention. (00:12:27) The role of diet and lifestyle in dementia prevention. (00:16:32) Understanding the broad impact of dementia on families. (00:21:10) Insights into dementia research and the importance of early intervention. (00:29:17) The link between chronic disease and dementia. (00:33:27) Discussing the prevalence and risk factors of Alzheimer’s and other dementias. (00:38:34) The importance of being proactive about brain health. (00:40:54) Addressing myths and misconceptions about dementia. (00:50:18) Practical tips for reducing dementia risk. (00:55:10) Max's final thoughts and call to action. Sponsors: ARMRA | Go to TryARMRA.com and use code DAVE to get 15% off your first order. Timeline | Try it out for yourself at TimelineNutrition.com/Dave and get 10% off your first order Resources: Little Empty Boxes Documentary: littleemptyboxes.com Max Lugavere’s Website: maxlugavere.com Instagram: @maxlugavere Twitter: @maxlugavere Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 18, 2024

Get ready for a shocking episode of The Human Upgrade with our guest, Adam Gavine, recorded at the 10th Annual Biohacking Conference. You’ll learn how the revolutionary Wasabi Method is changing the game in shock wave therapy. You’ll also gain understanding on how this innovative approach addresses pain management, boosts longevity, and enhances overall health. The Wasabi Method stimulates tissue regeneration, reduces inflammation, and improves immune function. Adam shares practical applications for this therapy, including its benefits for reproductive health and reversing tissue aging. Whether you're a biohacker, health professional, or wellness enthusiast, this episode is packed with valuable insights and actionable information. Timestamp Highlights: (00:01:14) What is Shock Wave Therapy? (00:04:59) How Adam Got into Shock Wave Therapy (00:08:10) Launching the Wasabi Method (00:11:39) Treating Trigger Points and Knotted Muscles (00:16:46) Applications for Erectile Dysfunction (00:21:34) Reversing Tissue Stiffness and Calcification (00:25:35) Using Wasabi Method for Collagen Production (00:32:29) Cell Membrane Permeability and Nutrient Absorption (00:37:03) Systemic Anti-Inflammatory Effects (00:45:02) Increasing White Blood Cell Count (00:48:12) Scar Tissue Management and Healing (00:54:46) Empowering Individuals in Their Health Journey (01:00:01) Practical Applications and Business Models Sponsors: ARMRA | Head to TryARMRA.com and use code DAVE for 15% off Your first order BEAM Pets | Go to BeamMinearls.com/Dave2024 for 20% off your first order. Resources The Wasabi Method | WasabiMethod.com Follow Wasabi Method on Instagram: @Wasabi_Method Follow Back To Function on Instagram: @back-to-function Biohacking Conference: https://www.biohackingconference.com/ Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ Studies referenced during the interview: Growth Factors & Angiogenesis Application of extracorporeal shock wave therapy in nervous system diseases - A review Extracorporeal shock wave therapy for treatment of vulvodynia: a prospective, randomized, double-blind, placebo-controlled study The Effect of Extracorporeal Shock Wave Therapy on Lower Limb Spasticity in Subacute Stroke Patients Efficacy of Extracorporeal Shockwave Therapy on Pain and Function in Myofascial Pain Syndrome IncRNA NEAT1-let 7b-P21 axis mediates the proliferation of neural stem cells cultured in vitro promoted by radial extracorporeal shock waves Effects of the extracorporeal shock wave therapy on the skin: an experimental study Molecular mechanism of action of low-intensity extracorporeal shockwave therapy for regenerating penile and peripheral nerves Comparison of shock wave therapy and US guided for shoulder injection therapy in patients with supraspinatus tendinitis Extracorporeal shock wave treatment in foot and ankle fracture non-unions — A review Treatment for Symptomatic Calcific Tendinopathy of the Shoulder: Ultrasound-Guided Needling Lavage and Extracorporeal Shock Wave Therapy vs Extracorporeal Shock Wave Therapy. A prospective observational study Effect of Low-Intensity Extracorporeal Shock Wave on the Treatment of Erectile Dysfunction: A Systematic Review and Meta-Analysis See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 14, 2024

On this special Upgrade Spotlight episode of The Human Upgrade, you'll learn about the critical connections between gut health, stress, and athletic performance with Hannah Kleinfeld from Omni Biotic. Find out how innovative probiotic formulations can enhance your overall well-being, reduce inflammation, and boost immune function. Hannah explains how gut health impacts both physical and mental performance, and shares practical tips for maintaining a healthy gut, personalizing your diet, and improving recovery. Whether you're an athlete looking to enhance performance or someone managing everyday stress, this episode provides valuable insights and actionable strategies to support a high-performance lifestyle. Tune in to discover how you can leverage the latest in gut health science to enhance your life. Timestamps: (00:01:03) Introduction to the Topic (00:04:51) Importance of Gut Health in Stress and Athletic Performance (00:12:27) How Probiotics Enhance Performance and Recovery (00:16:32) Impact of Stress on the Gut and Immune System (00:21:10) Case Study: Antibiotics and Gut Recovery (00:29:17) Probiotic Innovations from Germany (00:33:27) Gut Health and Chronic Illness (00:38:34) Strategies for Maintaining Gut Health (00:40:54) Personalized Gut Health Plans (00:50:18) Dietary Choices and Gut Health (00:55:10) Research Insights and Future Directions Sponsors Omni-Biotic | Go to Omnibioticlife.com and use code Dave20 for 20% off your order. Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Omni Biotic: omnibioticlife.com Instagram: @omnibioticlife Hannah’s LinkedIn: Hannah Kleinfeld YouTube: @Omni-Bioticlife1352 See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 13, 2024

Get ready for a fascinating episode with Darlene Teahen, a naturopath and researcher, who dives into the world of urine therapy. You'll learn about the science and history behind using urine for health benefits, including detoxifying the body, reducing inflammation, and boosting overall wellness. Darlene shares insights from her PhD research and offers practical advice on how to safely incorporate urine therapy into your routine. Darlene tackles societal taboos head-on, providing a thorough exploration of this ancient healing method backed by modern science. Whether you're curious about unconventional health practices or looking for new biohacking techniques, this episode delivers valuable information. This episode is packed with actionable insights on embracing unconventional methods, understanding the benefits of urine therapy, and integrating these practices into your daily life. Whether you're an avid biohacker or just exploring new health strategies, you'll find inspiration and practical advice here. Timestamps: 00:00:01 — Introduction 00:01:07 — History and Initial Reactions 00:02:14 — Scientific Backing 00:03:16 — Introduction of Guest: Darlene Teahen 00:03:30 — Personal Experiences and Skepticism 00:04:18 — Research and Evidence 00:05:49 — Practical Applications 00:06:53 — Societal and Medical Perspectives 00:07:40 — Personal and Professional Insights 00:08:03 — Emotional and Spiritual Aspects 00:08:58 — Advanced Techniques and Future Studies Sponsors: Zbiotics | Get 15% off now at Zbiotics.com/Dave LMNT | Go to DrinkLMNT.com/Dave for a free sample pack with any drink mix purchase Resources: Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Learn more about Darlene’s work: https://www.darleneteahen.ca/ Donate to Darlene's research: Donations for research https://paypal.me/DTeahen Follow Darlene on Instagram: @vitalityexpert Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 11, 2024

Get ready for an inspiring episode with Daymond John, the famous entrepreneur and Shark Tank star, recorded at the 10th Annual Biohacking Conference. You’ll learn how Daymond turned his life around after a serious health scare and how he uses biohacking to stay on top of his game. You’ll also discover the importance of hearing health, why he gave up alcohol, and how he embraces life with a new sense of adventure. Daymond offers his unique approach to parenting and the values he instills in his daughters, like understanding the power of curiosity and how it drives success. Daymond believes in constant growth and never settling. This episode is packed with actionable insights on cutting out negativity, trusting your gut, and using storytelling in business. Whether you’re an aspiring entrepreneur or looking to improve your personal life, this episode offers valuable lessons and inspiration. Check out The Shark Health to learn more: https://thesharkhealth.com/ Timestamps: [00:00:00] – Introduction by Daymond John [00:00:35] – Welcome and audience engagement: Daymond’s first experience at the event. [00:02:29] – Health scare: Daymond’s cancer diagnosis and the impact on his life. [00:07:14] – Embracing life: Daymond’s adventures and new appreciation for life. [00:10:03] – Raising daughters: Parenting and instilling values in his children. [00:15:38] – Never arriving: The continuous journey of personal and professional growth. [00:19:11] – Cutting out negativity: Removing toxic relationships for better health. [00:20:46] – Trust and intuition: How to identify trustworthy people in business. [00:23:19] – Entrepreneurs and storytelling: The power of storytelling in business success. [00:30:03] – Gut feeling: The importance of listening to your gut in decision making. [00:35:47] – Setting goals: The importance of goal setting and visualization. [00:40:50] – Empowering communities: Daymond’s mission with FUBU and beyond. [00:44:56] – Call to action: How to connect with Daymond and take advantage of resources. Sponsors Quantum Upgrade | Go to QuantumUpgrade.io/Dave for a 14-day free trial. Pendulum | Go to PendulumLife.com and use code Asprey20 for your first month of GLP-1 or any Pendulum formula. Resources The Shark Health | https://thesharkhealth.com/ Follow Daymond John on Instagram: https://www.instagram.com/thesharkdaymond/ Daymond John’s Website: https://daymondjohn.com/ Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 6, 2024

In this episode, Nicole Vignola, a neuroscientist with a BS in Neuroscience and a Master of Science in Organizational Psychology, explains how to rewire the brain for better decision-making and lasting change. You will learn about neuroplasticity, the science behind creating and undoing brain pathways, and practical strategies for forming new habits. Nicole shares the importance of visualization, taking strategic breaks, and focusing on strengths rather than weaknesses. She discusses the concept of mental currency and how to allocate energy effectively. The episode also covers how to manage negative thoughts, boost positive thinking, and the role of myelination in habit formation. Nicole explains how to use visualization paired with physical activity to reinforce new habits and prepare for setbacks. This episode provides actionable advice for anyone looking to improve mental health, enhance cognitive function, and create lasting positive changes in their life. Nicole’s new book, “Rewire: Break the Cycle, Alter Your Thoughts and Create Lasting Change (Your Neurotoolkit for Everyday Life)” is out now! Timestamps: (00:01:02) Introduction to Nicole Vignola and her work (00:01:44) The importance of affirmations and voice modulation (00:06:31) Fundamentals of neuroplasticity (00:09:42) The future of neuron regeneration (00:13:54) Habits, myelination, and cognitive energy (00:19:03) Mental currency and vigilance decrement (00:23:32) Trying harder vs. strategic rest (00:28:05) Morning vs. evening energy dynamics (00:29:24) The role of strategic breaks (00:31:27) Focusing on strengths over weaknesses (00:35:59) Managing negative thoughts and default mode network (00:43:03) Tools for creating positive thoughts (00:47:39) Healing trauma and synaptic rewiring (00:50:58) Gratitude practice and neuroplasticity (00:55:31) Longevity and healthy aging (01:01:20) Nicole's perspective on living past 100 Sponsors: Timeline | Go to TimelineNutrition.com/Dave to get 10% off your first order. Apollo Neuro | Head to ApolloNeuro.com/DaveAsprey to save 15% on an Apollo Wearable Resources: Nicole’s new book, “Rewire” is out now! Go to NicolesNeuroScience.com Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Nicole on Instagram: @nicolesneuroscience Learn How To Sleep: SleepWithDave.com Follow Dave on Instagram: @Dave.Asprey Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 4, 2024

Dr. Cate Shanahan returns to share vital insights on the dangers of seed oils and their impact on health. As a well-known Cornell-trained physician and author, Dr. Cate has spent years researching and advocating against the use of harmful vegetable oils. In this episode you’ll learn about the "Hateful Eight" oils and why they are detrimental to metabolic health. Dr. Cate explains the connection between these oils and chronic diseases, such as heart disease and diabetes. You will understand how to read labels to avoid these oils in everyday foods and get practical tips for making healthier dietary choices. Dr. Cate also covers the history and influence of the American Heart Association on dietary recommendations, revealing some eye-opening truths. Key takeaways you’ll gain include understanding the role of oxidative stress, the importance of choosing the right fats for a healthy diet, and how avoiding these oils can improve overall well-being. Timestamps: 00:00:00 — Opening 00:01:46 — Welcome and Introduction of Dr. Cate Shanahan 00:02:34 — The Reality of Food Deserts and Vegetable Oils 00:04:01 — The Ultra Wealthy and Their Dietary Choices 00:05:42 — Dr. Cate’s Personal Journey to Understanding Fats 00:11:10 — The Benefits of Avoiding Seed Oils 00:12:08 — The Hateful Eight Oils 00:19:07 — American Heart Association and Proctor & Gamble 00:28:15 — The Importance of Avoiding Oxidized Oils 00:39:05 — Clarifying Misconceptions About Omega-6 00:50:18 — The Impact of Diet on Family Structures 01:00:24 — The Role of Testosterone and Endocrine Disruptors 01:15:29 — Understanding Insulin Resistance 01:25:00 — The Slippery Slope of Statin Use 01:45:00 — Practical Tips for Avoiding Vegetable Oils 01:52:01 — Conclusion Sponsors: ARMRA | Go to TryARMRA.com and use the code DAVE to get 15% off your first order. Leela Quantum | Visit LeelaQ.com/Dave for 10% off. Resources: Dr. Cate’s book, “ Dark Calories ” is available for pre-order now! The book comes out on June 11th. Learn more about Dr. Cate: https://drcate.com/ Dr. Cate's Instagram: @drcaseyskitchen Levels’ Instagram: @DrCateShanahan Dave Asprey’s book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Follow The Human Upgrade: @TheHumanUpgradePodcast Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 30, 2024

In this episode of The Human Upgrade, you’ll learn how to enhance your health and longevity with insights from Dr. Casey Means, a Stanford-trained physician and co-founder of the metabolic health company, Levels. You’ll learn how to achieve good energy by enhancing metabolic health. Dr. Means shares valuable information on how food choices, metabolism, and chronic diseases are interconnected. She explains the science behind mitochondrial function and how your everyday choices impact your body's ability to generate energy. This episode offers practical tips for improving your metabolic health, covering areas such as diet, sleep, stress management, and reducing inflammation. You’ll hear about the importance of continuous glucose monitoring and personalized health data in maintaining metabolic health. Get ready to uncover the truth about modern healthcare systems and learn how to empower yourself with knowledge. Whether you're dealing with chronic conditions or looking to enhance your health, this episode is packed with essential information to guide your journey. Timestamps: (00:00:10) Introduction and importance of metabolic health (00:01:25) The connection between food and pharma systems (00:02:29) Dr. Means' background and new book "Good Energy" (00:03:33) The metabolic foundation of chronic diseases (00:05:59) The failure of Google as a health search engine (00:06:18) The link between migraines and mitochondrial function (00:07:52) Dr. Means' transition from ENT surgeon to metabolic health expert (00:10:25) The role of inflammation in chronic diseases (00:14:16) Working with her brother on the book (00:18:07) The story of Dr. Means' mother and the healthcare system's failures (00:20:55) Empowering patients with their health data (00:22:32) Addressing fear and misinformation in healthcare (00:30:44) First steps to improving metabolic health (00:37:17) The impact of fear on health (00:44:20) The concept of biochemical fear (00:50:04) Integrating natural signals into modern life Sponsors: Calroy | Head over to Calroy.com/Dave for an exclusive discount. Our Place | Go to FromOurPlace.com and use the code DAVE for 10% of your order. Resources: Dr. Casey book, “ Good Energy ” is out now. Levels Health: https://levelshealth.com Dr. Casey Means’ Instagram: @drcaseyskitchen Levels’ Instagram: @levels Levels’ YouTube: @LevelsHealth Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Follow The Human Upgrade: @TheHumanUpgradePodcast Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 28, 2024

In this episode, environmental journalist and seasoned activist David Steinman, with over 30 years of experience fighting against chemical toxins, shares his expertise on the impact of these harmful substances in our food supply. He highlights the serious health risks they pose, particularly to pregnant women and children, and offers practical tips on how to shield oneself and future generations from these dangers. Steinman delves into the benefits of organic foods, the effectiveness of water filtration, and the impact of making informed consumer choices. Through insights from his latest book, "Raising Healthy Kids," he equips listeners with the necessary tools to reduce toxin exposure and advocate for a healthier lifestyle. Tune in to gain valuable knowledge on how to safeguard your health and the environment from chemical toxins. Timestamps: (00:00:00) Introduction to the Crisis in America’s Food System (00:01:12) Introduction of David Steinman (00:02:22) Discussion on "The Better Baby Book" (00:05:09) The Impact of Pesticides on Fertility (00:10:20) Practical Advice on Water Filtration (00:21:03) The Importance of Organic Foods (00:35:30) Political Influence on Environmental Safety (00:39:46) Hope for Environmental Change (00:41:57) Personal Choices in Reducing Toxin Exposure (00:45:25) Discussing Systems Change for a Healthier Environment (00:52:15) The Significant Impact of Individual Actions (01:00:00) Conclusion: Steinman’s Call to Action Sponsors: ZBiotics | Go to Zbiotics.com/dave for 15% off your first order. spermidineLIFE | Go to spermidineLIFE.us and use code Asprey25 at checkout for 25% off your order. ARMRA | Go to https://www.TryARMRA.com and use code Dave for 15% off. Resources: " Raising Healthy Kids " by David Steinman is available on June 4th, 2024 Dave Asprey's book, 'Smarter Not Harder' is out now. Follow Dave on Instagram: @Dave.Asprey Follow The Human Upgrade: @TheHumanUpgradePodcast Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 24, 2024

We're previewing the 10th annual Biohacking Conference in Dallas, Texas, (May 30 - June 1) on The Human Upgrade ! Christian Drapeau and STEMREGEN are at the forefront of integrating plant-based innovations into regenerative medicine. By harnessing the power of unique plant extracts, STEMREGEN's approach stimulates the body's own stem cell production, providing a natural alternative to conventional stem cell therapies. This technique promotes rapid healing and rejuvenation and offers significant advancements in natural health and longevity. In this episode, delve into the groundbreaking work of Christian Drapeau presented at the upcoming Biohacking Conference. Attendees will discover how STEMREGEN plant-based solutions can dramatically increase the body's natural stem cell count, supporting faster recovery and enhanced vitality. Explore the potential of these innovations to reshape our understanding of health and wellness, paving the way for more accessible and effective regenerative treatments. Timestamps & Highlights: (00:01) Introduction to the episode and the significance of the Biohacking Conference. (01:05) Christian Drapeau's introduction and his journey in stem cell research. (01:35) Overview of STEMREGEN's new products at the Biohacking Conference. (01:58) Discussion on different types of stem cells and their applications. (03:21) Debunking myths around plant-based stem cells and their effectiveness. (04:12) Launch of new STEMREGEN products tailored for athletes and those seeking enhanced recovery. (05:08) Insights into the NSF certification process and its importance. (06:55) The role of systemic inflammation in stem cell functionality. (08:01) Introduction of STEMREGEN Mobilize to enhance capillary health. (09:17) Exploring the new STEMREGEN Signal for reducing systemic inflammation. Sponsors: STEMREGEN | Go to STEMREGEN.co/Dave for 20% off your order. Resources: 10th Annual Biohacking Conference: You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. https://biohackingconference.com Dave Asprey's NEW Book 'Smarter Not Harder' Follow Dave on Instagram: @Dave.Asprey Follow The Human Upgrade: @TheHumanUpgradePodcast Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Follow STEMREGEN on Instagram: @STEMREGEN See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 23, 2024

We're previewing the 10th annual Biohacking Conference in Dallas, Texas, (May 30 - June 1) on The Human Upgrade ! Mike McIntyre and ARRC are pioneering advancements at the intersection of frequency medicine and light therapy. By utilizing photons of light to carry therapeutic frequencies, their approach, known as photobiomodulation, opens new doors to enhancing health and meditative states. This technology not only enhances physical wellbeing but also elevates spiritual and mental health, establishing it as a cornerstone of innovative wellness practices. In this episode, explore the cutting-edge applications of photobiomodulation showcased at the Biohacking Conference. Attendees will experience firsthand how ARRC's light therapy technologies can transform their health by harnessing the power of light frequencies to stimulate cellular repair and enhance meditative practices, offering a glimpse into the future of holistic health enhancement. Timestamps: (00:01) Introduction to the episode and the Biohacking Conference. (01:12) Welcome Mike McIntyre and background into photobiomodulation. (01:55) Advancements in light therapy technology and its implications. (02:46) Discussion on using light therapy to enhance spiritual and meditative practices. (04:08) Observations on the impact of specific frequencies in light therapy. (06:02) The potential of light and frequency to influence health at a quantum level. (08:20) Benefits and experiences of using A RRC’s light therapy. (10:36) Details on session lengths and the immediate effects post-therapy. (14:29) Discussing the broader applications and scientific backing of light therapy. (16:55) Safety, side effects, and optimal dosing of light therapy treatments. (18:37) Encouragement to visit the Biohacking Conference and try out A RRC technology. Sponsors: ARRC LED | Go to ARRCLED.com to learn more! Resources: 10th Annual Biohacking Conference: You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. https://biohackingconference.com Dave Asprey's NEW Book 'Smarter Not Harder' Follow Dave on Instagram: @Dave.Asprey Follow The Human Upgrade: @TheHumanUpgradePodcast Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Follow ARRCLED on Instagram: @ARRCLED See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 22, 2024

We're previewing the 10th annual Biohacking Conference in Dallas, Texas, (May 30 - June 1) on The Human Upgrade ! Dr. Allen Meglin and Oxy Health are at the forefront of hyperbaric medicine, a field revolutionizing the way we enhance healing and cellular health. Hyperbaric oxygen therapy, as explained by Dr. Meglin, intensifies the body's ability to regenerate by significantly improving stem cell activation and optimizing the cellular environment for recovery. This therapy not only speeds up the healing process but also boosts overall cellular function, making it a critical tool in modern medical treatments. In this episode, discover the transformative impact of hyperbaric oxygen therapy, a highlighted technology at the Biohacking Conference. Attendees will learn how this treatment enhances natural healing processes, prepares the body for stem cell therapies, and promotes profound health improvements, peeking into the future of regenerative medicine. Timestamps: (00:01) Introduction to the episode and Biohacking Conference details. (00:47) Welcome Dr. Allen Meglin and his focus on hyperbaric therapy. (01:01) Dr. Meglin’s approach to integrating hyperbarics with stem cell therapy. (02:00) The scientific basis for hyperbarics in enhancing stem cell outcomes. (03:07) Explanation of stem cells' role in natural healing processes. (04:13) Variables influencing the effectiveness of hyperbaric therapy. (06:11) Discussion on the dual effects of hyperbaric therapy: stress and relaxation. (08:52) The variety of hyperbaric chamber options and their therapeutic uses. (00:10:35) Clinical Experiences with Hyperbarics. Sponsors: Oxyhealth | Go to Oxyhealth.com to learn more Resources: 10th Annual Biohacking Conference: You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. https://biohackingconference.com Dave Asprey's NEW Book 'Smarter Not Harder' Follow Dave on Instagram: @Dave.Asprey Follow The Human Upgrade: @TheHumanUpgradePodcast Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Follow Oxyhealth on Instagram: @Oxyhealth See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 21, 2024

We're previewing the 10th annual Biohacking Conference in Dallas, Texas, (May 30 - June 1) on The Human Upgrade ! Dr. Patrick Porter and BrainTap are pioneers in the intersection of neuroscience and technology, transforming the way we approach mental and cognitive health. BrainTap, a device developed under Dr. Porter's guidance, merges light and sound therapy with guided visualization to enhance the brain's neuroplasticity. This technology not only offers a leap in personal development but also aligns perfectly with the biohacker's toolkit for optimized mental performance. In this episode, explore the established benefits of BrainTap technology, a favorite at the Biohacking Conference. Attendees will have the opportunity to experience firsthand how BrainTap's approach to brain enhancement can invigorate daily mental health routines, making sophisticated neuroscience accessible to individuals seeking to maximize their mental capacity. Timestamps: (00:01) Introduction to the episode and the significance of the Biohacking Conference. (01:20) Dr. Patrick Porter introduces BrainTap and its foundational science. (02:11) Latest research findings on BrainTap's impact on cognitive function and sleep improvement. (03:27) Comparing the effects of psychedelics and BrainTap on the brain's default mode network. (04:49) Discussion on the expansive use and benefits of BrainTap technology. (06:17) How BrainTap assists in the right neural pruning to enhance mental function. (08:12) Clarifying the concept of subspace in learning and brain function. (11:17) New studies on BrainTap's role in academic performance and dementia. (14:04) Community impact and personal experiences at the Biohacking Conference. Sponsors: BrainTap | Go to BrainTap.com/Dave for an exclusive offer. Resources: 10th Annual Biohacking Conference: You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. https://biohackingconference.com Dave Asprey's NEW Book 'Smarter Not Harder' Follow Dave on Instagram: @Dave.Asprey Follow The Human Upgrade: @TheHumanUpgradePodcast Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 20, 2024

We're previewing the 10th annual Biohacking Conference in Dallas, Texas, (May 30 - June 1) on The Human Upgrade! Dr. Brandon Crawford and 528 Innovations are at the forefront of laser technology development for biohacking. Traditionally seen as a tool for medical professionals, laser technology has made significant strides in becoming accessible for personal health optimization. Dr. Crawford’s work with 528 Innovations has led to the creation of a new laser device that enhances health and performance by manipulating light to achieve precise biological effects. This episode offers insights into the technology being featured at the Biohacking Conference, where attendees can experience the latest innovations that promise to elevate personal wellness routines. By harnessing the power of advanced laser technology, 528 Innovations is setting new standards in the field, aiming to transform everyday health practices with tools previously only available to specialists. Timestamps & Highlights: (00:01) Introduction to the episode and the historical significance of lasers in biohacking. (01:04) Preview of the Biohacking Conference and the introduction of innovative technologies. (01:38) Dr. Brandon Crawford discusses the versatility and legacy of racehorse lasers in therapy. (02:04) Exploration of how high-value professionals adopt biohacking technologies. (03:03) Announcement of Dr. Crawford's new laser product at the Biohacking Conference. (04:40) Discussion on the portable design and transformative potential of the new laser. (06:07) Dr. Crawford outlines the intended impact and the platform nature of the new laser technology. (07:05) Safety features and regulatory aspects of the new laser. (08:29) Insights into the research behind the new laser and its effects on brain function. (13:12) Pricing information and the value proposition for different users (home users vs. clinicians). Sponsor: Go to 528innovations.com to learn more! Introducing the 528 Innovations 5 Series Laser Therapy Device, now available for pre-sale! Pre-order now for you chance to win! Secure this revolutionary product, launching this week and shipping later in the year. Resources: Dave Asprey's NEW Book 'Smarter Not Harder' 10th Annual Biohacking Conference: biohackingconference.com for tickets Follow Dave on Instagram: @Dave.Asprey Follow The Human Upgrade: @TheHumanUpgradePodcast Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 16, 2024

In this episode of "The Human Upgrade," you will learn from Dr. Elizabeth Yurth, an expert in orthopedics, cellular medicine, and regenerative medicine, about the significant health benefits of spermidine, a supplement that enhances longevity and supports robust health. Dr. Yurth discusses the crucial role of spermidine in promoting autophagy, the body's natural process for clearing out damaged cells, which can lead to better cellular health and a more youthful body. She also dives into how spermidine supports kidney health and how it can be combined with NAD to maximize anti-aging effects. Additionally, you will discover practical tips from Dr. Yurth on integrating these powerful supplements into your daily routine to maintain energy levels, improve cellular function, and sustain a vigorous and healthy life as you age. This episode provides deep insights into making informed choices about supplements that support long-term health goals. Timestamp Highlights: (00:00:01) Introduction: Background and the inception of biohacking. (00:01:08) Early biological management and its long-term benefits. (00:01:57) Misconceptions about fasting and the role of spermidine. (00:02:43) Dr. Uth's journey from orthopedics to longevity medicine. (00:06:17) Deep dive into spermidine: benefits, sources, and mechanisms. (00:10:43) Dietary sources of spermidine and its importance in diet. (00:16:02) Spermidine as a crucial nutrient for autophagy and its mechanisms. (00:19:13) Comparing spermidine with fasting and rapamycin for longevity. (00:22:25) Practical dosing advice for spermidine. (00:33:24) The optimal timing and method of spermidine supplementation. (00:41:58) Spermidine's effects on hair growth and its potential as a topical application. (01:07:17) Discussion on the future of longevity treatments and gene therapy. Sponsors: spermidineLIFE | Go to spermidineLIFE.us and use code Asprey25 at checkout for 25% off your order. EnVy | Go to envypillow.com and use code DAVE at checkout for an exclusive discount Head to QuantumUpgrade.io/Dave for a free trial Resources: Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Boulder Longevity Institute: https://boulderlongevity.com/ Follow spermidineLIFE: @spermidinelife.us Follow Dave on Instagram: @Dave.Asprey Follow The Human Upgrade: @TheHumanUpgradePodcast Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 14, 2024

In this episode of The Human Upgrade, Peter Diamandis shares his expert insights on using artificial intelligence to improve health and extend life. Listeners will learn about the latest advancements in AI-driven health technologies and therapeutic practices that could revolutionize wellness and longevity. Peter discusses the concept of longevity escape velocity and how close humanity is to achieving it. He also explores the economic models that might make cutting-edge therapies more accessible to a broader audience. Additionally, Peter provides personal anecdotes about his health routines, including his dietary strategies and his use of red light therapy, offering listeners practical advice on integrating these technologies into their own health regimes. This conversation sheds light on the future of health care and personal wellness, providing listeners with valuable strategies to enhance their quality of life. Timestamps: (00:00:01) Opening and introduction to the show (00:01:06) Peter's use of AI and its impact on health (00:07:42) Discussion on Ketamine and neuroplasticity (00:14:26) XPRIZE updates and new initiatives (00:17:45) The concept of longevity escape velocity (00:26:52) Financial models and accessibility of advanced therapies (00:39:13) The power of a supportive personal network (00:54:18) Peter's personal diet and longevity strategies (01:03:09) Red light therapy and its benefits (01:21:09) Closing remarks and future plans Sponsors: Calroy | Head to Calroy.com/Dave for an exclusive discount Viome | Go to Viome.com/Dave to save $110 on the Full Body Intelligence Test. Resources: Peter Diamandis Official Website | https://www.diamandis.com/ XPRIZE | https://www.xprize.org/ Purpose Finder | https://purposefinder.ai/ Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Follow The Human Upgrade: @TheHumanUpgradePodcast Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 10, 2024

In this special Upgrade Spotlight episode of "The Human Upgrade," Philipp Samor von Holtzendorff-Fehling, founder and CEO of Quantum Upgrade and Leela Quantum, joins the show to talk about quantum energy. Since his last appearance on the show, Philipp has made significant advances in harnessing quantum energy to promote health and wellness. You'll learn about the science behind quantum energy, how it can positively impact your life, and the practical ways you can use this technology to boost your own health, mood, and vitality. Philipp also shares insights into the journey that led him from a high-stress corporate world to pioneering in holistic health innovations, offering you inspiration and actionable tips to apply in your daily life. Join us to see how the latest in quantum energy can make a real difference in how you feel every day. Timestamps: (00:01:03) Introduction to Quantum Energy and Biohacking (00:04:51) Philipp's Journey from Corporate to Quantum Healing (00:12:27) Understanding Quantum Systems and Human Biology (00:16:32) The Science and Technology behind Quantum Upgrade (00:21:10) Evidence and Impact of Quantum Energy Devices (00:29:17) Expanding Human Consciousness through Quantum Fields (00:33:27) The Future of Health and Quantum Technologies (00:38:34) How Quantum Energy Can Shape Our Health and Environment (00:40:54) Philosophical Insights on Energy, Consciousness, and Healing (00:50:18) Closing Thoughts and How to Access Quantum Technologies Sponsors: Go to QuantumUpgrade.io/Dave and get a 14 Day Free Trial Resources: Follow Philipp on Instagram: https://www.instagram.com/philipp_vhf/ Quantum Upgrade Instagram: https://www.instagram.com/quantumupgrade.io/ Dave Asprey’s Book ‘Smarter Not Harder:’ https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Follow The Human Upgrade: @TheHumanUpgradePodcast Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 9, 2024

In this special "Asprey Archive" episode of The Human Upgrade, you’ll find out why you’re tired, how to fix it and ways to increase your energy. Fatigue is a hidden epidemic, with chronic fatigue syndrome being the most severe end, but most people (in the U.S.) are experiencing some level of being flat-out tired as hell. Our guest is Ari Whitten, Ph.D. (Cand.), CES, PES, who came on the show in 2022. Ari argues that as a culture, we have normalized fatigue. In his book, “EAT FOR ENERGY: How to Beat Fatigue, Supercharge Your Mitochondria, and Unlock All-Day Energy,” he explains that 5.4 million adults in the U.S. have been diagnosed with chronic fatigue syndrome (the most severe case of fatigue). However, the true fatigue epidemic affects 50 to 100 times more people. Ari outlines the major factors impacting mitochondrial health, including poor sleep, excess body fat, and an unhealthy gut, and offers solutions like nutritional strategies and key supplements to enhance energy. With over 25 years in natural health science and a personal history with chronic fatigue, Ari brings invaluable insights into combating fatigue through his Energy Blueprint programs and podcast, where he connects with experts on revitalizing human energy. Sponsors: Pendulum | Get 20% off membership at https://pendulumlife.com with code Asprey20 ARMRA | Go to https://www.TryARMRA.com and use code Dave for 15% off Resources: Ari's book: FOR ENERGY: How to Beat Fatigue, Supercharge Your Mitochondria, and Unlock All-Day Energy Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Follow The Human Upgrade: @TheHumanUpgradePodcast Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 7, 2024

On today's episode, Jerry Colonna shares his transformative journey from a high-powered venture capitalist to a Buddhist coach. You'll learn about the profound impact of “radical self-inquiry" on leadership and life, illustrating how deep personal development can reshape personal and professional relationships. You'll also learn how mindfulness and self-awareness are crucial for effective leadership. Whether you're a seasoned leader or simply aspiring to improve, this conversation offers invaluable insights into executive coaching, Buddhism and personal transformation, making it essential for anyone aiming to foster a compassion and understanding. Highlights: (00:01:01) - Jerry Colonna's Transformative Journey (00:05:51) - The Impact of Material Success (00:13:27) - Mindfulness in Leadership (00:17:32) - Deep Mental States Through Meditation (00:22:10) - Themes of 'Reunion' (00:30:17) - Philosophy of Radical Self-Inquiry (00:34:27) - Leadership and Self-Awareness (00:39:34) - The Practice of Continuous Personal Development (00:41:54) - Becoming a Leadership Coach (00:51:18) - Connecting Mindfulness with Professional Relationships (00:56:10) - Long-Term Benefits of Self-Inquiry (01:00:42) - Insights from Executive Coaching (01:03:00) - Future of Leadership and Compassion Sponsors: LEELA Q | Visit LeelaQ.com/Dave for 10% off Timeline Nutrition | Go to TimelineNutrition.com/Dave and get 10% off your first order. Resources: Jerry’s Website - https://www.reboot.io/team/jerry-colonna/ Jerry’s Book – Reunion: Leadership and the Longing to Belong Follow Jerry on Instagram: @Jerry.Colonna Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Follow The Human Upgrade: @TheHumanUpgradePodcast Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 2, 2024

Today on The Human Upgrade, Dr. Anurag Singh, a renowned expert in muscle biology and aging, shares his expertise on the impact of GLP-1 agonists like Ozempic and Wegovy on weight loss, muscle health, and aging. In this episode, you'll learn about the science behind these popular drugs, their potential benefits, and the risks involved. Discover how you can maintain muscle mass while losing weight, enhance your mitochondrial function for better health, and what the future holds for medical treatments in weight management. Gain expert insights into making smart choices for your long-term health and wellness, whether you're considering these treatments or just curious about new health technologies. Timestamped Highlights: (00:00:00) Introduction to GLP-1 agonists and their popularity in weight loss. (00:01:40) Guest introduction: Dr. Anurag Singh's expertise and background. (00:02:50) Dr. Singh discusses the primary functions and uses of GLP-1 drugs. (00:06:23) The significant muscle loss associated with GLP-1 drug use. (00:10:01) Addressing common misconceptions and concerns about GLP-1 agonists. (00:15:34) How GLP-1 agonists affect mitochondrial function and overall metabolism. (00:20:30) Comparing the effects of fasting to GLP-1 drugs on weight loss and muscle preservation. (00:28:43) New testing methods for mitochondrial function and their implications. (00:35:00) Potential future directions in GLP-1 treatment and muscle preservation strategies. (00:41:48) The concept of 'Ozempic face' and its effects on personal appearance and self-esteem. (00:50:04) Discussion on 'Urolithin A' and its role in mitochondrial health and muscle strength. (01:04:02) Predictions for the next innovations in weight loss and muscle health treatments. Resources: Vitamin Dake | www.VitaminDAKE.com Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Follow The Human Upgrade: @TheHumanUpgradePodcast Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Sponsors: STEMREGEN | Go to www.STEMREGEN.CO/DAVE for 20% Off Timeline Nutrition | Go to www.TimelineNutrition.com/Dave for an exclusive discount. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 30, 2024

Today's episode focuses on Cancer with a true expert, Mark Lintern. You'll learn about the surprising links between infections, inflammation, and our body's powerhouses - the mitochondria. This is a chance to arm yourself with cutting-edge theories that could change the way we treat cancer. Simple changes in treatment perspectives might be the key to unlocking new ways to tackle cancer and by the end of this episode, you'll have a fresh arsenal of knowledge to rethink cancer's causes and solutions. This is an eye-opening discussion that promises to transform the way we approach this formidable disease. Timestamp Highlights: (00:00:01) Introduction to a new theory about cancer (00:01:08) The interplay between mitochondrial dysfunction and genetic factors (00:02:08) Evaluating cancer from a citizen scientist's perspective (00:03:15) Challenging mainstream cancer narratives with personal research (00:07:49) How biases affect cancer research and therapy development (00:09:40) Exploring the Warburg effect in cancer metabolism (00:23:05) Investigating pathogens as a potential trigger for the Warburg effect (00:27:18) Fungal connections to chronic disease and cancer (00:35:32) How pathogens and inflammation contribute to cancer's growth (00:37:37) Importance of addressing inflammation and fungal infections in cancer (00:43:32) Estrogen's role in cancer promotion (00:47:10) The connection between methyl deficiency and cancer (00:49:17) Metformin's dual role in blood sugar regulation and antifungal activity (00:50:01) Wrapping up the conversation with final insights Sponsors: ARRC LED | For More Information Visit www.ARRCLED.COM EnVy | Upgrade your sleep and skin health now at www.enVyPillow.com , use code DAVE10 at checkout. Resources: https://www.cellsuppression.com/ Help Mark advance his research: https://www.gofundme.com/f/help-mark-lintern-advance-cancer-treatment Website - www.cellsuppression.com Book - The Cancer Resolution Follow Yes To Life: @YesToLifeCharity Donate to Yes To Life: https://yestolife.org.uk/ Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Follow The Human Upgrade: @TheHumanUpgradePodcast Moldy Movie: www.MoldyMovie.com Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 25, 2024

Get ready for a journey that takes you beyond the pain of heartbreak and into a world where loss transforms into growth with science journalist Florence Williams, who shares her personal triumph over the heartbreak of divorce, which inspired her to write a book on the subject. This episode sheds light on how heartbreak reshapes our bodies and minds. You'll gain valuable tactics for emotional healing, understand the crucial role of touch in regaining trust, and see how therapeutic practices like EMDR and rituals can offer relief. For those on the mend or helping others heal, this discussion is packed with practical advice to help you transform the trials of heartbreak into a journey of empowerment. This episode provides clear steps to recover and emerge stronger from life's emotional challenges. Timestamp Highlights (00:02:26) Florence Williams’ Journey Through Divorce (00:07:42) Divorce as a Story of Inflammation (00:13:43) Rebuilding Connection Post-Heartbreak (00:18:02) Embracing Beauty and Awe in Healing (00:23:22) Therapeutic Use of Psychedelics in Overcoming Heartbreak (00:34:33) Reestablishing Trust After Betrayal (00:38:04) The Healing Power of Touch and Oxytocin (00:44:51) Safe Relationships and Self-Discovery Post-Divorce (00:50:33) Journaling as a Tool for Processing Emotions Sponsors ARMRA | Go to https://www.TryARMRA.com and use code Dave for 15% off BEAM Minerals | Go to www.Beam Minerals.com/Dave2024 for 20% off your first order. Resources Get your copy of ‘Heartbreak’ by Florence Williams: https://www.florencewilliams.com/books-2 Florence Williams website: https://www.florencewilliams.com/ Follow Florence Williams: @Florence999 Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Follow The Human Upgrade: @TheHumanUpgradePodcast See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 23, 2024

Managing your stress effectively and building resilience just got easier with Dr. Aditi Nerurkar's guidance on The Human Upgrade. This episode tackles 'toxic resilience,' revealing its impacts on health and well-being. You'll gain insights into the HPA axis—the body's command center for stress response—and learn practical techniques to turn stress into a growth tool. Dr. Aditi introduces the 'Rule of Two,' a simple yet powerful approach to adapting to stress and shows how neuroplasticity can retrain your brain for better stress management. You'll also discover tips for setting digital boundaries, fostering gratitude, managing a full email inbox, and understanding the connections between stress management and longevity. It's all about taking actionable steps toward a more resilient, empowered life. Timestamp Highlights: (00:01:21) - The Pressures of the Pandemic and the Surge in Stress (00:02:08) - Introducing Dr. Aditi Nerurkar and Her Journey Through Burnout (00:05:06) - The Concept of 'Toxic Resilience' and Sustainable Stress Management (00:10:16) - The Physiological Responses to Stress and the HPA Axis (00:12:12) - Transforming Stress from Maladaptive to Adaptive (00:17:16) - The Importance of Understanding Personal Stress Thresholds (00:21:06) - Empowering Change and Managing Internal Alerts (00:25:15) - The 'Rule of Two' in Stress Adaptation (00:32:21) - The Role of Neuroplasticity in Resilience (00:37:13) - Combining Conventional Medicine with Stress Management Techniques (00:39:29) - How Dr. Nerurkar Achieves an 'Inbox Zero' Lifestyle (00:40:59) - The Connection Between Stress Management and Longevity Sponsors Pendulum | Get 20% off membership at https://pendulumlife.com with code Asprey20 Timeline Nutrition | Go to https://www.timeline.com/dave and get 10% off your first order. Resources Get your copy of ‘ The 5 Resets ’ by Dr. Aditi Nerurkar Follow Dr. Aditi on Instagram: @draditinerurkar Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 18, 2024

In this special Asprey Archive episode you’ll learn that while yes, testosterone fuels energy and performance, it’s not the be-all and end-all solution for men’s health woes. A systems biology approach considers many other aspects and provides a broader perspective about what’s going on with you. This conversation features board-certified urologist Tracy Gapin, M.D. He joined us in 2022 for this episode to discuss new ways for men to improve their health and performance. He uses epigenetic coaching, hormones, peptide therapy, biometric monitoring, and unique nutrition and lifestyle interventions. In his book, “ Male 2.0™: Cracking the Code to Limitless Health and Vitality ,” he says medical school, residency training and even a two-decade career in urology and surgery specialties didn’t teach him how to get to root causes of men’s issues and solve them. He had a health crash of his own at 42. Since neither he nor his doctor had good answers, he went on a quest of discovery and change. He founded the Gapin Institute for High Performance Medicine and created the proprietary N1 Performance Health Program to go beyond conventional options. This conversation goes even further into what creates epigenetic signals that affect the function and expression of your genes. You’ll learn, too, that your mindset, stress and environment—and how you do or don’t control those things—have everything to do with your energy and focus. If you’re aiming for higher performance, Dr. Tracy suggests a trifecta that makes sleep a priority, builds resilience to stress, and creates consistent behaviors with intention. Sponsors: EnVy | Go to https://www.envypillow.com/ and use code DAVE10 at checkout for an exclusive discount. Resources: Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: Gapin Institute for High Performance Medicine Instagram: @DrTracyGapin Instagram: @Dave.Asprey YouTube: @DaveAspreyBPR See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 16, 2024

In today’s episode you’ll explore the complexities of memory with Dr. Charan Ranganath, a top expert in cognitive neuroscience. This episode takes you through the fascinating ways our brains record, process, and utilize memories to navigate daily life and shape our futures. You’ll learn how memory impacts decision-making, the truth about common myths, and the role of groundbreaking research in our understanding of cognitive function. Dr. Ranganath shares insights from his book "Why We Remember," shedding light on the brain's ability to predict and prepare for what comes next. Whether you're a seasoned biohacker or just starting, this conversation offers valuable perspectives on the science of memory that will change how you think about your mind. Timestamp highlights (00:01:03) The Role of Memory in Shaping Our Reality (00:04:51) The Truth about Remembering and Forgetting (00:12:27) Psychedelics, Plasticity, and the Future of Memory Research (00:16:32) The Ethics of Memory Enhancement (00:21:10) Harnessing Memory for Predicting the Future (00:29:17) How Memory Evolves with Age (00:33:27) The Power of Pattern Recognition in Human Intelligence (00:38:34) Debunking Memory Myths with Dr. Ranganath (00:40:54) The Role of Diet and Lifestyle in Memory Preservation (00:50:18) What 'Spider Sense' Says About Our Predictive Brains (00:55:10) Building a Life of Meaningful Memories (00:59:42) How Long Would You Want to Live if Your Memory Stayed Intact? Sponsors Sunlighten | Head to Sunlighten.com/dave to save up to $600 STEMREGEN | Go to STEMREGEN.co/Dave for 20% off Resources Get your copy of ' Why We Remember ' by Dr. Charan Ranganath Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dr. Ranganath on Instagram: @TheMemoryDoc See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 11, 2024

Join Dave Asprey for a fascinating discussion with Colleen Cutcliffe, Ph.D., on leveraging the power of GLP-1 for natural weight management and overall well-being. Discover how probiotics can naturally stimulate GLP-1 production in the body, helping reduce food cravings and maintain a healthy gut lining. We delve into the differences between pharmaceuticals and natural probiotics, the importance of GLP-1 for longevity, and practical tips for optimizing your microbiome health. Whether you're battling cravings or seeking to prevent diabetes and its associated risks, this episode sheds light on natural, effective strategies for a healthier life. Timestamp Highlights: (00:00:01) Introduction to GLP-1 and weight management (00:01:06) Colleen Cutcliffe, PhD, on natural ways to stimulate GLP-1 (00:04:41) The role of microbiome in regulating GLP-1 and cravings (00:16:00) The GLP-1 probiotic: benefits beyond weight loss (00:34:13) Dietary interventions to support GLP-1 probiotics (00:42:23) Personal experiences and results with GLP-1 probiotics (00:51:01) The different pendulum products and who should take them (00:59:23) How GLP-1 probiotics impact the gut lining and overall health (01:03:56) GLP-1 and its connection to longevity and disease prevention Sponsors: Pendulum | Get 20% off membership at https://pendulumlife.com with code Asprey20 ARMRA | Go to https://www.TryARMRA.com and use code Dave for 15% off ARRC LED | For More Information Visit ARRCLED.com Resources: Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Instagram: @Dave.Asprey Pendulum GLP-1 Probiotics: https://pendulumlife.com (Code: Asprey20 for 20% off) Instagram: @pendulumlifeco See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 9, 2024

Today you'll step inside the real world of fame with Ramon Hervey II, the mastermind manager behind iconic figures like Vanessa Williams, Bette Midler, and Richard Pryor. He is author of "The Fame Game: An Insider's Playbook for Earning Your 15 Minutes." With years of experience guiding celebrity journeys, Ramon dismantles the myths surrounding fame and success. In this episode, he shares invaluable insights on why pouring your heart into your work and letting excellence lead is more fulfilling and enduring than the pursuit of fame. Ramon, a Master of Media and public perception, brings a wealth of knowledge from his time shaping the narratives of household names. Get ready to redefine your ambitions and align your pursuits with the values that truly matter. You’ll step beyond the veneer of fame into a world where your achievements stand the test of time. (00:00:06) Introduction to the complexities of fame (00:01:06) Ramon's correction and insights into the unpredictability of fame (00:04:04) The statistical rarity of becoming famous (00:06:03) The truth behind fabricating fame in the entertainment industry (00:09:18) The importance of authenticity and integrity (00:21:54) Ramon's experience with the toxic side of fame (00:29:32) The gratitude for positive fan interactions (00:32:13) Ramon's advice for influencers on handling fame (00:41:19) How industries can shift and impact your fame (00:42:27) Dave's creation of the biohacking movement (00:48:41) The strategic management of public image and fame (00:52:10) The dangers of seeking fame for fame's sake (00:58:55) The misuse of fame and its consequences (01:07:13) The role of media and public perception (01:14:04) Ramon's take on fame as currency and liability (01:20:22) The Tenets of Fame - managing fame without destruction Sponsors: Timeline Nutrition | Go to https://www.timeline.com/dave and get 10% off your first order 40 Years of Zen | Go to https://www.40YearsOfZen.com/Dave for an exclusive offer. Resources: Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: www.herveyandcompany.com IG - @trichemon FB - Ramon Hervey II Twitter: @coolramon See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 4, 2024

Today you’ll learn about female hormones: what they are, what they do, and what disrupts them. You’ll learn about the hormonal shifts that happen at different ages and life stages and get tips on how to balance hormones and make them work for you, not against you. This conversation features Anna Cabeca, D.O. . Dr. Anna is a Doctor of Osteopathy who’s triple-board certified in gynecology and obstetrics, integrative medicine, and anti-aging and regenerative medicine. She has additional certifications in functional medicine, sexual health, and bioidentical hormone replacement therapy. She joins this special preview episode to talk about female hormones. It’s her particular area of expertise and one of The Human Upgrade’s all-time Top 10 podcast topics. Today’s hormone discussion includes: How hormone disruptors go beyond stress to mold, and product and environmental toxins How estrogen levels change over time What’s going on with progesterone, pregnenolone and DHEA, too What happens to hormones during perimenopause and menopause What’s causing brain fog What to know about bioidentical hormones How detoxing affects hormones How to keep your vaginal microbiome balanced How “food as medicine” helps balance hormones How hormones influence longevity And much more! For the past 20 years, Dr. Anna's educated and helped women with their hormones through her private practice, books, online videos and articles. Learn more about her work with women’s hormone health: “ MenuPause: Five Unique Eating Plans to Break Through Your Weight Loss Plateau and Improve Mood, Sleep, and Hot Flashes ” “The Hormone Fix: Burn Fat Naturally, Boost Energy, and Stop Hot Flashes the Keto-Green™️ Way” “Keto-Green™️ 16” Sponsors: Quantum Upgrade | Go to https://quantumupgrade.io/dave for a 7-day Free Trail Neurohacker Senolytic | https://Neurohacker.com/Dave to get 15% off. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 2, 2024

What if you could catch cancer in its earliest stages, when it's most treatable—would you seize that chance? Our guest today is Dr. Josh Ofman, the president of GRAIL, and he's pioneering early cancer detection in a revolutionary new way. You'll discover the cutting-edge advances in multi-cancer early detection that are transforming the fight against this swift and silent killer. You'll also learn about the full potential of the GRAIL gallery test in your proactive health management. This technology is ushering in a new era in cancer care but also signals a paradigm shift in disease prevention. Learn why yearly screenings are your best strategy in the race against cancer. Prepare to dive deep into how the latest biotech innovations could significantly extend your life span! Timestamp Highlights (00:01:03) An Unsettling Trend in Cancer Proliferation (00:04:51) Introducing Dr. Josh Ofman and the GRAIL Test (00:12:27) The Revolutionary Approach of Multi-Cancer Early Detection (00:16:32) The Shift to Biological Signals in Cancer Detection (00:21:10) The Empowering Aspect of Knowing Your Cancer Status (00:29:17) How GRAIL's Gallery Test Can Change the Paradigm of Cancer Treatment (00:33:27) The Critical Nature of Annual Cancer Screening (00:38:34) How Early Detection Affects Treatment Options and Survival (00:40:54) The Future of GRAIL in Other Disease Pathways (00:50:18) Combating Fear and Misconceptions Around Cancer (00:55:10) The Impact of Socioeconomic Factors on Cancer Incidence (00:59:42) The Pivotal Role of Data in Personalized Health Sponsors ARRC LED | The perfect device for daily home use. For more information visit arrcled.com . Leela Quantum | Visit www.LeelaQ.com/Dave for 10% Off Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’: daveasprey.com/books GRAIL Multi-Cancer Early Detection Test: Visit www. Galleri.com/Dave to see if you’re eligible for a $50 off limited-time online-only offer. GRAIL Research and Studies: grail.com/clinical-studies GRAIL on Twitter: @GRAILbio See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 28, 2024

I had the pleasure of talking with Dr. Christina Rahm, who has an inspiring journey from a pharmaceutical executive to an advocate for integrating holistic health solutions with rigorous scientific methods. We dive into the impact of spirituality on wellness, the transformative power of neural feedback, and the intersection of technology and ethics in health. Dr. Rahm shares her insights into combating health issues with nanotechnology and discusses the influence of the environment on our well-being. (00:00:01) Introducing Dr. Christina Rahm and her diverse expertise in health and science (00:02:17) The transparency and ethics in the pharmaceutical industry (00:07:07) Transition to holistic health solutions and bioengineering innovations (00:14:10) Addressing the pervasive health effects of fungus and mold (00:27:11) Biotechnology's role in creating a brighter future for human health (00:38:04) Discussing the unexpected benefits of childhood diseases on immune function (00:50:31) Exploring annual detox rituals and their scientific basis (01:03:01) Handling criticism with humor: The "Your Mom" strategy (01:06:57) Announcement of Upgrade Labs locations and offerings Sponsors: Mitosynergy | Exclusive offer for listeners – 15% off by going to www.Mitosynergy.com/Dave ARMRA | Go to www.TryARMRA.com and use code Dave to get 15% off your First Order Resources: Dr. Christina Rahm's website: https://drchristinarahm.com/ Root Brands: https://therootbrands.com/ Upgrade Labs: https://upgradelabs.com/ Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Dr. Chrsitina Rahm’s Instagram Page: https://www.instagram.com/drchristinarahm/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 26, 2024

In this profound episode, Maria Menounos shares her journey through significant health challenges, including a brain tumor and diabetes, and how she emerged more resilient and health focused. Renowned for her vibrant career in entertainment and now as a wellness advocate, Maria delves into the transformative power of facing mortality, redefining medicine, and leveraging biohacking to enhance her life. She gives actionable advice for those looking to preserve their health while pursuing their dreams and the importance of aligning career success with personal well-being. (00:00:01) - Maria's resilience through her health battles (00:03:29) - How health challenges can redefine life's purpose (00:14:18) - Yoga Nidra and the shift from anxiety to empowerment (00:23:25) - The importance of biohacking in Maria's recovery (00:34:16) - Sunlight and its underrated health benefits (00:47:30) - The rise of biohacking technologies and their accessibility Sponsors BiOptimizers | Go to www.bioptimizers.com/Dave for 10% off Timeline | Go to www.TimelineNutrition.com/Dave to get 10% off your first order Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Heal Squad: https://www.healsquad.com/ Maria Menounos Instagram: @mariamenounos See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 21, 2024

Today, Calley Means joins the show to march onward on his war path to changing the incentives of modern health. He’s a champion of food and lifestyle practices as medicine—and, in May of this year, he’s putting out a new book on the subject which we outline today, called Good Energy. His sister, Dr. Casey Means, is the co-author of Good Energy. You know her from a past appearance on this show and as the founder of Levels so this mission really is a family affair in the best way possible. Going from a food lobbyist to the other side of the fence, Calley is a deeply serious and dedicated champion for the people. But he brings much more to the table today than a polished delivery and a new book; he is also the co-founder of True Medicine, which works to connect tax-advantaged spending to healthy food and exercise. It’s helped hundreds of thousands of people access affordable care by leveraging the convoluted systems currently in place to block them from doing so—no easy task. In this conversation, Calley lays the foundation for our food culture as it stands today—bleak, corrupt, poisoned, sick, and getting sicker. We deconstruct the layers of federal agencies and historical precedent that have brought us to this point, and we’re direct in our suggestions (demands) on how to fix it. And all the facts are laid bare. Dots are connected in broad daylight, on network television, and within the algorithms that power our social feeds. Our kids are at stake, and the only option is to take affirmative action on what we know is right. (00:01:19) Calley’s Inspirations & Metabolic Mission (00:11:16) Redefining the Meaning of Medicine (00:19:21) Is America a Viable Place To Raise Healthy Kids? (00:30:41) Meaningfully Changing Healthcare Incentives (00:42:56) Now What—How Does Society Make Positive Change? (00:49:34) The Media’s Role in Society’s False Narratives (00:56:49) Undoing the Damage of the Food Pyramid Sponsors ARRC LED | The perfect device for daily home use. For more information visit arrcled.com . Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Good Energy: The Surprising Connection Between Metabolism and Limitless Health Truemed: truemed.com The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 19, 2024

How can we make our furry best friends live longer, healthier lives? A true pioneer in this field, Dr. Matt Kaeberlein, is here to unpack this important subject while highlighting the crossover between human and canine longevity. You read that right; this episode isn't just for dog lovers—it's a deep dive into longevity for humans, too. Dr. Matt Kaeberlein, who's the CEO of Optispan and a key figure in the Dog Aging Project, brings a wealth of knowledge from his distinguished career in aging and healthspan research. He's an Affiliate Professor at the University of Washington and a notable figure in gerontology, recognized by organizations like the American Association for the Advancement of Science and the Gerontological Society of America. Matt's work is groundbreaking, demonstrated in over 250 scientific papers on aging, numerous prestigious awards, and he's even a Fellow of several aging associations. He's on a mission to unlock the secrets of aging, not just in humans, but in our four-legged companions as well. We explore the accuracy of measuring age with telomeres versus epigenetics and get into the nitty-gritty of diet's impact on longevity for both dogs and humans, reminding us it's not just about living longer, but living well. Matt explains the impressive trial results on rapamycin for reducing age-related inflammation, a breakthrough that's not just exciting for us but also for our pets. Finally, we touch on how AI is revolutionizing our approach to understanding and extending our healthspan. For those who want to get more involved, check out dogagingproject.org . It's not every day you meet someone who's made such significant strides in understanding aging across species. So whether you're a pet parent or just passionate about extending your own health span, this episode is for you. (00:01:31) Dogs Are the Bridge Between Lab Studies & Human Longevity (00:11:09) Exploring the Impact of Diet on Longevity (00:18:50) How Our Unique Biology Impacts Aging (00:26:33) Exploring How Size & Diet Impact Health Across Species (00:37:55) Fighting Age-Related Inflammation with Rapamycin (00:56:40) AI Interventions for Longevity Testing Sponsors ARMRA | Try it out for yourself at TryARMRA.com . Use code “Dave” to get 15% off your first order STEMREGEN | Go to STEMREGEN.co/Dave for 20% off. Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Learn More: dogagingproject.org Website: optispan.life X: @mkaeberlein Listen: The Optispan Podcast with Matt Kaeberlein The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 15, 2024

I’m excited to welcome back Jewels Arnes, an author, ascension coach, and the founder of BioQuantum Skincare Technology. Jewels has more than 30 years of experience in energy medicine and intensive consciousness work. In today’s episode, Jewels explains scalar waves, ORMUS, and the quantum level. She shares how these concepts all contribute to her BioQuantum Skincare line and the intention she poured into the products. We also talk about how and why Jewels moved away from psychedelics and regular meditation, and how she tunes into frequencies without them. Plus, we get into the spiritual ego, how to master your triggers, the frequency of DMT, and Jewels’ role as an ascension coach. Unlike my analytical brain, Jewels sees the world through frequencies, so this was a fun conversation with fresh perspectives. (00:01:13) Dave’s Experience with ORMUS (00:06:59) Dangers of the Spiritual Ego (00:15:02) The Sphere of Spirituality & Science (00:18:11) How To Tune Into Frequencies (00:23:34) Cultivating Awareness of Our Triggers (00:27:57) Creating Products with Intention (00:32:22) What Is ORMUS? (00:38:43) Operating at the Quantum Level (00:49:22) The Frequency of DMT (00:55:23) Unboxing the BioQuantum Product Line (00:56:39) What Is Ascension Coaching? Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Shop: becomingbioquantum.com/dave to save 22% on the Scalar 33 ORMUS Activator Website: becomingbioquantum.com Instagram: @jewels.arnes Instagram: @becomingbioquantum Podcast: becomingbioquantum.com/podcast YouTube: @BecomingBioQuantum The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 14, 2024

What is the role of Ego? Is AI going to kill us? Is there hope for the future of our species? These are just a few of the big questions you’ll tackle in today’s enlightening and esoteric episode. I’m joined by Teal Swan, a thought leader, bestselling author, and international speaker who is on a mission to reduce human suffering. After a challenging upbringing, Teal emerged with a unique ability to talk about psychology, shadow work, and the nature of our world. Teal shares the unusual and special way she sees the world. We talk about her ESP powers, how to identify a narcissist, and her favorite dimensions. We also get into the divine masculine vs. the divine feminine, the nature of ego, and how to build trust in the world and others. (00:01:37) Finding Forgiveness in Betrayal (00:11:34) Teal’s Take on Artificial Intelligence (00:14:43) Teal Swan’s ESP Powers (00:23:22) Exploring Intention in Art (00:25:47) Upgrading Human Software & Hardware (00:27:48) How Teal Functions in the “Real” World (00:32:39) Trusting in the World (00:35:19) What’s the Nature of Ego? (00:39:14) Discovering Different Dimensions (00:42:46) Divine Feminine vs. Divine Masculine (00:52:31) Is There Hope for the Future of Our Species? (00:53:58) What Is a Synchronization Workshop? Sponsors Quantum Upgrade | Go to QuantumUpgrade.io/Dave for a 7-Day Free Mitosynergy | Get 15% off now at Mitosynergy.com/Dave Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: tealswan.com Instagram: @tealswanofficial YouTube: @TealSwanOfficial TikTok: @tealswanlive Podcast: Teal Swan The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 12, 2024

Today’s guest is none other than Shawn Stevenson. If you’re not already familiar with Shawn’s work, he’s the author of the USA Today National bestseller Eat Smarter, the international bestselling book Sleep Smarter, and the creator of the widely popular health podcast, The Model Health Show. Shawn is one of those guys who embodies peace and calm, after an impressively transformative journey stemming from a background of health challenges at least as severe as mine. After recovering, he became a researcher and nutritionist experienced in biology and nutritional science. We dive into a crucial element of biohacking I am always keen to highlight—friendship, or in this case, community. Based on research from Shawn’s latest book, Eat Smarter Family Cookbook, we talk about his current mission on the path to wellness: creating a culture of wellness around the dinner table, how communal meals impact our health and longevity, and filling the void of connection we all so desperately need these days. Shawn shares insights from his own family’s dinner table, his tips for implementing family meals into your weekly routine, and the encouraging science and data behind how it supports physical and spiritual nourishment, nervous system regulation, stress management, and more. If you like this episode, I encourage you to go pick out a good cut of meat and cook food for someone you care about—or simply do anything that's an act of service that nourishes another human being. Here’s to cultivating strong relationships, imbuing our food with love, and honoring the act of nourishing ourselves and our families. (00:01:16) Cultivating Peace & Presence Through Nervous System Regulation (00:10:00) Cultural Connections to Health, Longevity & Childhood Obesity (00:25:20) Family Dinners for Nourishment, Mindfulness & Building Stronger Bonds (00:43:45) Kids in the Kitchen: Fostering Enjoyment, Skill & Service in Cooking (00:59:48) Heart Meditations, Trauma Healing & the Science of Emotional Exchange Sponsors Bioptimizers | Go to Bioptimizers.com/Dave for 10% off any order. LeelaQ | Visit LeelaQ.com/Dave for 10% off your order. Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Podcast: The Model Health Show Instagram: @shawnmodel YouTube: The Shawn Model Read: Eat Smarter Family Cookbook by Shawn Stevenson The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 7, 2024

Today’s guest has the coolest title I’ve ever heard—mind architect. Peter Crone is a world-renowned spiritual teacher, mind-body wellness coach, and life transformation expert. He’s worked with everyone from athletes, to actors, to billionaire CEOs, to everyday people trying to do their best. Peter helps people achieve spiritual freedom, mental peace, and physical vitality, which all align with biohacking in a big way. In this episode, we dig deep into the limiting beliefs that shape our behavior and relationships. We talk about discerning between reality and the stories we tell ourselves. Peter gives advice on overcoming perfectionism, strengthening your intuition, and recognizing your innate value. We also explore how to reframe language, the value of curiosity, and how to harness losses into learnings that unlock your greatest potential. It’s a fascinating conversation. You can hear more from Peter at the upcoming Biohacking Conference. Get your tickets at biohackingconference.com . (00:03:33) Where Biohacking Meets Energy Work (00:06:28) Accessing a Spiritual State Without Drugs (00:11:04) Recovering From Perfectionism (00:19:14) Reality vs. the Stories We Tell Ourselves (00:29:42) Healing Wounds From Birth (00:38:31) Why Fear Is the Enemy of Health (00:43:18) How To Train & Strengthen Intuition (00:56:01) Recognizing Your Innate Value (01:03:30) How Can We Learn From Our Elders? (01:06:19) Peter’s Freedom Program Sponsors Timeline Nutrition | Go to TimelineNutrition.com/Dave to get 10% off your first order. Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: petercrone.com Instagram: @petercrone Facebook: Peter Crone - The Mind Architect TikTok: @petercroneofficial YouTube: @PeterCroneOfficial The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 5, 2024

Today, we're diving into a topic that's on everyone's mind, but often misunderstood: gluten. Joining the show on this gluten-decoding mission is none other than Dr. Peter Osborne, aka the Gluten-Free Warrior. Dr. Osborne is a powerhouse of knowledge in nutritional health, particularly regarding gluten sensitivity and food allergies. As the founder of Gluten Free Society, the author of the bestseller, No Grain No Pain, and the host of the Glutenology MasterClass Series, he's at the forefront of functional medicine, helping countless individuals combat chronic and autoimmune diseases. His insights are crucial for anyone navigating the complexities of a gluten-free life. In this episode, we explain why gluten isn’t good for anyone—even if you don’t have symptoms or a diagnosed celiac problem. As a foundation, we lay out the differences between gluten sensitivity and celiac disease, covering the surprising connections between dairy, gluten allergies, and mold. Dr. Osborne also highlights why common gluten-free substitutes like corn, oats, and rice aren't the safe havens we wish we were. You’ll hear about the nefarious ways Big Food is keeping our country sick and how to start taking charge of your own health in simple, free ways. Dr. Osborne shares his recommended diet, the rule of thirds, and how to effectively shift your eating habits. He recognizes the frustration and struggle many people face in finding effective professional help, and shares his tips for spearheading your own healing while collaborating with competent professionals. This episode isn't just about gluten; it's a deep dive into understanding your body, your diet, and how to collaborate with your doctor to find the health solutions that work for you. (00:01:48) Why We Should All Be Gluten Free (00:11:46) Big Food’s Role in Our Declining Health (00:28:31) When to Enjoy (and Avoid) Sugar, Soybeans & High Oxalate Foods (00:42:39) Change Your Diet & Biohack Your Way to Better Health (01:00:15) How To Respectfully Advocate for Your Own Health Sponsors BEAM Minerals Pets | Go to BeamMinerals.com/DAVE2024 for 20% off your first order. Viome | Go to Viome.com/Dave to save $110 on the Full Body Intelligence Test. Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: drpeterosborne.com Read: No Grain, No Pain by Peter Osborne YouTube: Peter Osborne Instagram: @drosborne The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Feb 29, 2024

Today we’re talking about something a little different—the “weird,” esoteric, metaphysical stuff. I’m joined by Laura Coe, who was a successful healthcare tech entrepreneur before selling her company and returning to her passion for philosophy. She is now an author, certified life coach, and Akashic Records reader. Never heard of the Akashic Records? Laura explains exactly what they are, and how they can help you understand yourself on a deeper level to find more joy, peace, and prosperity in your life. We explore the big questions… Who can access the Records? How do you know if they’re even real? Then, we get into the nitty gritty… How do you learn to read them? What can you ask and not ask? Can they help you sell your house or make more money? Laura and I also talk about how to tap into your intuition as an entrepreneur, the stigmas against spirituality, and why more of us than we think probably have psychic gifts. If you’re skeptical of this stuff, I’m going to ask you to suspend your disbelief and listen with an open mind. Laura’s perspective will give you a lot to think about. Why not give it a try? (00:03:47) What Are The Akashic Records? (00:13:15) The Akashic Records as a Grid of Interconnection (00:18:47) Validating The Akashic Records for Skeptics (00:23:37) Coming Out As Spiritual (00:26:53) How Long Does It Take To Learn The Akashic Records? (00:29:42) The Craziest Questions People Ask (00:32:39) Listening to Your Inner Knowing (00:38:01) What Can’t You Ask The Akashic Records? (00:41:55) Sentences That Open the Records (00:47:22) Healing Yourself Through Healing Others (00:48:54) Can It Help You Sell Your House? (00:56:11) Taking the “Woo Woo” out of The Akashic Records Sponsors Mitosynergy | Get 15% off now at Mitosynergy.com/Dave Calroy.com | Head over to Calroy.com/Dave for an exclusive discount Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: lauracoe.com The Little Soul School: littlesoul.school Read The Nature Of Series: lauracoe.com/books Instagram: @laurascoe The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Feb 27, 2024

Today I’m talking with one of the most sought-after celebrity trainers on the planet. Jason Walsh has trained stars like Matt Damon, Miles Teller, Brie Larson, and Bradley Cooper for some of the most physically demanding roles of their careers. He’s also the founder of Rise Nation, a global fitness studio powered by the VersaClimber, where you train like an athlete. On today’s episode, we talk about how Jason rose to success as a celebrity trainer. He shares the moments that defined his life and career, plus his advice for anyone who wants to get started in the fitness industry. We also go deep on the painful parts of entrepreneurship—unpacking the betrayals and heartbreaks we’ve both experienced as founders. We explore ways to train your brain and your body for resiliency, and how to redefine forgiveness as an energetic shift. We also talk about Jason’s new protein company, Rise 311. Plus, his take on why you don’t need to train for an hour a day to get results. (00:02:06) How Jason Became a Celebrity Trainer (00:22:22) The Rewards of Being Disciplined (00:25:40) How to Rise in Your Fitness Career (00:33:52) Building Rise Nation Step by Step (00:40:13) The War Against Small Businesses (00:42:47) Heartbreaks & Betrayals in Business (00:48:23) Train Your Brain to Reframe Trauma (00:53:47) Redefining Forgiveness (01:00:33) The Rise of Rise 311 (01:02:32) Finding Joy & Resilience Sponsors Mitosynergy | Get 15% off now at https://Mitosynergy.com/Dave Calroy | Go to https://Calroy.com/Dave for an exclusive discount Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: rise-nation.com Rise 311: rise311.com Instagram: @risenation Jason’s Instagram: @risemovement TikTok: @climbrisenation The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Feb 22, 2024

Blood sugar management as a biohack captures attention for its innovative approach to health. Today's guest, Jessie Inchauspé, stands out as an expert in guiding practical glucose management, smarter nutritional choices, and unveiling the intricate relationship between diet, blood sugar levels, and overall well-being. Behind the popular Instagram account @GlucoseGoddess, Jessie educates millions on groundbreaking food habits and has achieved notable success as a French biochemist and New York Times bestselling author, with over a million copies sold of her works, "Glucose Revolution" and "The Glucose Goddess Method," in 40 languages. Her unique combination of mathematics and biochemistry expertise opens up the secrets of blood sugar and its significant impact on physical and mental health. The conversation zeroes in on Jessie's mission to make complex science accessible through simple, transformative tips. Topics include her groundbreaking research, The Glucose Method study, the launch of her Anti-Spike supplement, and her signature four hacks for glucose management after consuming carbs. The dialogue also covers the benefits of real versus fake sugar, the underlying causes of insulin resistance and diabetes, and how blood sugar spikes influence aging. This episode unveils Jessie's remarkable discoveries and biohacks for glucose management, which are crucial for fertility, PCOS, and understanding the health impacts of lifestyle choices like alcohol and nicotine. Jessie's practical insights offer a path to enjoying favored foods with minimal bodily impact, appealing to both biohacking aficionados and those embarking on a health journey. (00:02:28) Understanding Glucose’s Role in Our Health (00:14:27) Enjoying Carbs Without Negative Side Effects (00:23:27) The Real Cause of Insulin Resistance & Diabetes (00:34:23) Addressing Alcohol, Nicotine & The French Paradox (00:54:22) The Glucose Goddess Method Study (01:05:47) Glucose Management for Fertility, PCOS & PMS Cravings Sponsors Timeline Nutrition | Go to TimelineNutrition.com/Dave and get 10% off your order. Sunlighten | Head to Sunlighten.com/dave to save up to $600 when you order. Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: glucosegoddess.com Instagram: @glucosegoddess Read: Glucose Revolution by Jessie Inchauspé Read: The Glucose Goddess Method by Jessie Inchauspé The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Feb 20, 2024

Today we're talking about testosterone replacement and unpacking the novel concepts of progressive overload and variable resistance training—both methods to gain, and keep, muscle mass in your body without living in the gym. I’m joined by strength expert, entrepreneur, past guest of the show, and PhD, John Jaquish. John has spent years researching and developing improved approaches to health. Inventor of X3, a technology that is proven to develop muscle much faster than conventional weight lifting with the lowest risk of joint injury, Dr. Jaquish’s methods are used in training the world's most elite athletes as well as Olympians. Aligning with the most basic tenet of biohacking, if you can achieve all of your physical or athletic goals in half the time of your competitors, why not explore the option? John is as gracious as he is informed in this one, detailing the benefits of variable resistance training and indulging me in a super deep dive into diet and nutrition experimentation, testosterone replacement therapy, and efficient muscle growth. You’ll learn what he eats every day to look as good as he does. You’ll get repetition-count-specific recommendations on ultra-quick workout routines. And you’ll learn the very surprising amount of carbohydrates I ingest every single day (a number that will shock many of you). Sponsors BEAM Minerals Pets | Go to BeamMinerals.com/DAVE2024 for 20% off your first order. ARMRA | Try it out for yourself at tryarmra.com . Use code DAVE to get 15% off your first order. (00:02:39) Masterclass on Efficient Muscle Building (00:16:43) How are Shaolin Monks & Gymnasts So Strong? (00:23:46) Testosterone Replacement Therapy (TRT) (00:38:40) How Protein Impacts Muscle Growth (00:47:55) Breakthrough Personal Research on Carbohydrates (00:58:31) Weight Lifting is a Waste of Time Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: jaquishbiomedical.com Instagram: @drjaquish YouTube: Jaquish Biomedical Read: Weight Lifting Is a Waste of Time Read: Osteogenic Loading: A New Modality To Facilitate Bone Density Development How to Build Strength Faster – John Jaquish, Ph.D. #863 Building Strength Isn’t About Weight Lifting Anymore – John Jaquish, Ph.D. #862 The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Feb 16, 2024

Welcome to a special Upgrade Spotlight Edition, where I introduce you to someone who's genuinely changing the game. Our carefully selected guest today is a renowned pharmacist, an author, and a pioneer in biohacking for skin longevity: Dr. Nayan Patel. Dr. Patel is a trailblazer in the world of antioxidants, specifically glutathione. If you've been following biohacking or are a regular listener, you know that glutathione is a key antioxidant with vital functions, including skin health. Dr. Patel's expertise in absorbable glutathione and anti-aging sciences is unparalleled. Dr. Patel holds a unique patent for transdermal glutathione delivery, a groundbreaking method of introducing this crucial antioxidant directly through your skin with his company Auro Wellness. His book, The Glutathione Revolution, dives deep into this topic. In this episode, we delve into why glutathione is essential for skin longevity. Dr. Patel shares insights on his innovative formula and technology for absorption at Auro Wellness, which has shown promising results in reducing fine lines, cellulite, and even promoting hair growth. As someone who champions scientifically-backed products and real results, I'm excited to discuss how Dr. Patel's work is a true game changer. I know the power of glutathione. I've been using it for nearly two decades, especially during my battle with toxic mold exposure. And now, thanks to innovators like Dr. Patel, we're moving from intravenous methods to transdermal applications—it's truly revolutionary. For those eager to try, visit aurowellness.com and use code DAVE10 for a discount. (00:01:14) Biohacking Benefits of Glutathione & New Absorption Technology (00:08:32) The Auro Skincare Stack & How Glutathione Enhances Skin Longevity (00:20:13) Reducing Cellulite & Fine Lines with Glutathione (00:35:01) Glutathione for Hair Growth & Toxin Removal Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Shop Auro Wellness: aurowellness.com (use code DAVE10 for 10% off) Read: The Glutathione Revolution by Dr. Nayan Patel and Dr. Mark Hyman The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Feb 15, 2024

I’m pumped to welcome one of the hosts of the Mind Pump Podcast, top trainer and entrepreneur Sal Di Stefano. Mind Pump pulls back the curtain on the health, fitness, and nutrition industries, cuts through the pseudo-science, and offers science-backed solutions for enhancing performance while emphasizing health. Sal started his journey in the gym at age 14, and I admire how he’s steadily grown a meaningful business around biohacking fitness. On today’s episode, we take on some weighty topics like weight training vs. cardio, why veganism is dangerous, and why reverse dieting may actually be the key for results. Sal explains his fitness philosophy, which focuses on functional movement, reframing your mindset around exercise, and consistency above all else. We also get into the nutrition side of things. Sal and I break down how much protein you should be eating per day, plus our favorite proteins—and the evil ones we avoid. We also talk carbs. Do they make you fat? How do they impact performance? What are the best sources? Then, we get fired up talking about how you can fire up your metabolism. This episode is for everyone, from gym newbies to serious bodybuilders. And check out my episode on The Mind Pump Podcast to get a double dose of me and Sal (watch or listen). (00:01:03) Are Bodybuilders the Edgiest Biohackers? (00:04:51) Strength Training vs. Cardio (00:12:27) Strength Training as a Longevity Tool (00:16:32) Moving Toward Functional Movement (00:21:10) Reframing Movement in Your Mind (00:29:17) Why Veganism Is Dangerous (00:33:27) Do Carbs Make You Fat? (00:38:34) Should You Reverse Diet? (00:40:54) How Much Protein Should You Eat? (00:50:18) Is There Any Good Reason To Eat Chicken? (00:55:10) Winning Carb Choices (00:59:42) Sal’s #1 Recommended Supplement (01:02:00) The Single Biggest Fitness Mistake Sponsors Mitosynergy | Get 15% off now at Mitosynergy.com/Dave 40 Years of Zen | Upgrade Your Brain in 5 Days by going to 40YearsOfZen.com/Dave Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Mind Pump Podcast: mindpumppodcast.com Mind Pump Training Protocols: mindpumpmedia.com/maps-fitness-products Mind Pump Instagram: @mindpumpmedia Sal’s Instagram: @mindpumpdistefano X: @mindpumpsal TikTok: @mindpumpmedia YouTube: @MindPumpShow The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Feb 13, 2024

Dive into yoga nidra with Tracee Stanley, a renowned teacher and author who unveils the transformative power of rest. Her book, "Radiant Rest," showcases the vital role of recovery in biohacking, advocating for the strength found in stillness. Tracee, with over twenty years of experience and collaborations with icons like Marianne Williamson, is a leader in the realm of deep rest and clarity. Her latest work, "The Luminous Self," deepens this exploration, aligning with our aim to unlock inner power for a fulfilling life. Today, we delve into yoga nidra's science, its profound effects on our brain, and how it connects us to our roots, reshapes habits, and promotes deep healing. Tracee's approach not only offers a pathway to better understanding and caring for ourselves but also redefines our relationship with rest and the world. Her insights are essential for anyone seeking a holistic biohack for body and mind wellness, providing clarity, compassion, and the gift of deep rest. (00:00:40) Accessing Real Rest & Peace With Yoga Nidra (00:12:25) One Free Daily Practice for Better Sleep, Focus & Productivity (00:26:34) Exploring Death Practices & Connecting to Nature (00:42:34) Creating a Legacy of Peace: Passing on Indigenous Traditions & Teachings (00:53:50) Healing a Sleep Deprived World & Confronting the Root Cause of Suffering (01:08:13) Exploring Tracee’s Tools for Connection & Healing Sponsors Calroy | Calroy.com/Dave for an exclusive discount Bioptimizers Blood Sugar Breakthrough | Go to BloodSugarBreakthrough.health/Dave and use code “Dave10” for 10% off your order. Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Read: The Luminous Self by Tracee Stanley Read: Radiant Rest by Tracee Stanley Website: traceestanley.com Instagram: @tracee_stanley The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Feb 8, 2024

Today’s show is a masterclass in improving your skin without going under the knife. I’m excited to welcome back Dr. Rob Whitfield, an Austin-based plastic surgeon who specializes in breast implant removal surgeries and advanced cosmetic procedures. He invented the famous “No-Cut” Facelift, which revolutionized non-surgical facelifts for a more natural appearance. I worked with Rob on a “No-Cut” Facelift, and he removed excess skin from my back after my weight loss. I got to be the guinea pig, and now I’m sharing everything I learned with you. On today's episode, I recount my experience and results with these procedures. Dr. Rob explains what a “No-Cut” Facelift is, plus other non-surgical procedures to tighten fat, remove excess skin, and reduce wrinkles. We talk about radio frequency-assisted lipolysis, SoftWave therapy, Morpheus8, and a whole lot more. Plus, we get into foods that hurt your skin, injectable vs. topical peptides, and biohacking skincare. Basically, it’s everything you need to know for younger, healthier-looking skin. And let’s face it, we all want that. (00:01:58) Dave’s Experience Working With Dr. Rob (00:08:48) What Is a “No-Cut” Facelift? (00:19:10) Shrinking Fat With Radio Frequency Assisted Lipolysis (00:22:13) Zoom Lifts & More Non-Surgical Procedures (00:29:02) What Is SoftWave Therapy? (00:33:28) Biohacking for Skincare (00:34:47) Morpheus8: Good or Bad? (00:35:53) Treatments for Excess Skin (00:37:44) How Bad Are BBLs? (00:41:57) Does Your Skin Have a Biological Clock? (00:45:32) Foods That Hurt Your Skin (00:48:18) Topical vs. Injectable Peptides (00:50:17) The Bright Side of Sun Exposure (00:53:42) What To Do for Your Skin at 25 Sponsors Leela Q | Visit LeelaQ.com/Dave for 10% off. Timeline Nutrition | Go to TimelineNutrition.com/Dave and get 10% off your order. Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: drrobertwhitfield.com The HARP™️ Method: harp.health Instagram: @breastimplantillnessexpert Instagram: @drrobwhitfield Facebook: Dr. Rob Whitfield MD YouTube: @breastimplantillnessexpert TikTok: @drrobertwhitfield How Breast Implants Compromise Your Health and Make You Sick #1043 The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Feb 6, 2024

Inflammation is at the root of everything. More inflammation means less energy and a higher risk of every disease. Today, we’re digging into exactly why inflammation is so insidious with functional medicine nurse practitioner Maggie Berghoff. Maggie is a USA Today National Best-Selling author of the book Eat to Treat: Your Three-Step Plan To Reduce Inflammation, Detoxify Your Life, And Heal Your Body. She is also the founder of wellness supplement and non-toxic home line DETOXDaily. In this episode, we talk all about inflammation—what causes it, how it hurts us, and how to combat it. We explore all the different types of inflammation, including physiological vs. psychological inflammation– and dig into how inflammation intersects with hormone health, thyroid function, and metabolic syndrome. Maggie also shares her perspective about shedding shame around eating, and why perfectionism can be even more toxic than actually toxic foods. Plus, I share a lot of horrifying (but medically useful) information about urine. You’ll be equally intrigued and grossed out. (00:01:29) The Ills of Inflammation (00:07:23) Physiological vs. Psychological Inflammation (00:15:00) 3 Things That Cause Inflammation (00:25:26) Are We More Inflamed Now Than Ever? (00:27:19) Where Do You Start Combating Inflammation? (00:30:09) What Is Your Inflammation Type? (00:35:50) When Your Hormones Are in Havoc (00:46:58) Metabolic Syndrome’s Role in Inflammation (00:49:22) The Nightmare of Poor Sleep (00:55:18) Shedding Shame Around Food (01:02:20) Why Not Just Take Aspirin? Sponsors Quantum Upgrade | Go to QuantumUpgrade.io/dave for a 15 day free trial Stemregen | Go to Stemregen.co/dave for 20% off Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: maggieberghoff.com Eat To Treat: eattotreat.com DETOX Daily: yourdetoxdaily.com Instagram: @maggie_berghoff Facebook: Maggie Berghoff TikTok: @maggie_berghoff Linkedin: Maggie Berghoff The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Feb 1, 2024

Meet a man who makes miracles happen. Today, I’m joined in the studio by Hal Elrod, author of the international bestseller The Miracle Morning and his newest book, The Miracle Equation. After overcoming multiple near-death experiences and financial hardships, Hal channeled his adversity into helping others overcome their own challenges. His Miracle Morning approach has impacted millions of lives. On today’s episode, Hal tells us all about his updated version of The Miracle Morning. He explains SAVERS, the six foundational practices that will transform your morning and change your life. We also talk about tips for hacking your sleep, productivity, and relationships. Hal shares the stories of his devastating car accident and rare cancer diagnosis—and the superpowers he gained from coming back to life. We explore how these near-death experiences changed his perspective on life and what he values most. He also tackles some tough questions… Should we try to help everyone? What does it mean to be a “man”? And what does it take to truly serve others? There’s so much to take away from Hal’s refreshing and optimistic perspective. (00:03:20) Creative Ways To Hold Yourself Accountable (00:13:57) Ditching Veganism (00:21:08) Hal’s Near-Death Experiences (00:27:35) Taking Your Health in Your Hands (00:29:37) Did Hal Come Back With Superpowers? (00:31:55) Are You Supposed To Help Everyone? (00:40:51) How the Miracle Morning Changed Hal’s LIfe (00:43:42) What Does It Mean To Be a “Man”? (00:51:25) Customizing Your Morning To Meet Your Needs (00:54:05) The Six Savers for Success (00:56:53) Tips To Save Your Sleep (01:01:51) The MVP of Personal Development Practices (01:06:14) Nourishing Our Connections Sponsors Viome | Go to Viome.com/Dave and save $110 on the full-body intelligence test. Neurohacker | Go to Neurohacker.com/Dave and try it risk free for up to 100 days. Use code “DAVE” at checkout for 15% now. Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Read: The Miracle Morning and The Miracle Equation Website: halelrod.com Facebook: Hal Elrod X: @HalElrod YouTube: @HalElrod The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jan 30, 2024

Imagine the benefits of stem cell regeneration without needles or a high cost. Today, I'm excited to introduce Christian Drapeau, inventor of a groundbreaking plant-based stem cell product for health and longevity. Christian is more than a scientist; he's a stem cell expert and herbalist, pioneering plant-based stem cell enhancers. Yes, plants and stem cells together! His background from McGill University and work at Stemtech International make him a leading voice in stem cell science. His book, 'Cracking the Stem Cell Code,' reveals how our bodies use stem cells for repair, and his latest research shows how aquatic plants can boost stem cell production, like nature's own fountain of youth. We'll explore how Christian's journey in ancient herbalism led to innovative discoveries in stem cell enhancement and clarify the difference between traditional procedures and products like STEMREGEN. Stay tuned for key answers: How do stem cells promote longer, healthier lives? What's the truth about stem cells and cancer? When's the best time to start using these products? I'll also share my personal routine for maximizing stem cell supplement effects. If you're excited about affordable, effective health benefits, try STEMREGEN. Visit stemregen.co/dave to save 20% on your order. (00:01:09) STEMREGEN: Understanding The Herbalism x Stem Cell Crossover (00:12:21) Stem Cells & Longevity 101 (00:23:55) The Historical Context of Healing & Longevity with Plants (00:32:05) Affordability & Cancer Prevention with STEMREGEN (00:44:27) Preventing Kidney Stones & Lowering Your pH (00:57:37) Dave’s Biohacking Stack for STEMREGEN Enhancement (01:05:51) Improving Mitochondrial Function & Measuring Age Sponsors Bioptimizers | Go to Bioptimizers.com/dave , and use code "Dave10" for 10% off Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: stemregen.co/dave Instagram: @stemregen YouTube: STEMREGEN The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jan 25, 2024

Today, we’re digging into specifics about food that you haven’t heard on the show before. This one may very well influence you to rethink your “healthy” diet and change how you feel about food completely. To get there, I’m excited to welcome back Teri Cochrane, an integrative practitioner and pioneer in personalized healthcare. Teri is the founder of the Global Sustainable Health Institute® and developer of The Cochrane Method®, a future-facing algorithm for decoding the human body. Teri is also one of the world’s leading experts on dietary amyloids, which is a topic I love talking about. In today’s episode, we get into what amyloids are and how they turn on viruses, cause cancer, and shorten our lives. We also explore the dangers of oxalates and histamines, plus hacks to reduce and release them. Teri and I both have our own recipes for releasing oxalates that you can try at home (they’re surprisingly simple). We talk about how dirty poultry is killing us—and how superfoods like kale and almonds aren’t any better. We break down the benefits of regenerative farming, and share ways to make your dollar stretch if you can’t afford grass-fed meat. Plus, Teri tells us what she personally eats. (00:02:01) The Big 4 Metabolic Impairments (00:08:21) The Dangers of Oxalates (00:12:02) The Fifth Disruptor: Histamine (00:16:22) Becoming Your Own Body Interpreter (00:28:41) How Do We Get Off Oxalates? (00:35:41) Dave’s Recipe for Releasing Oxalates (00:44:40) Hacks for Histamines (00:50:32) Amyloid 101: What You Should Know (00:56:56) Should You Beware of B6? (00:59:54) What’s the Best Kind of Protein? Sponsors Calroy Arterosil & Vascanox Bundle | Head over to calroy.com/dave for an exclusive discount. Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: tericochrane.com Instagram: @tericochranebeyondnutrition YouTube: @TeriCochrane The Global Sustainable Health Institute: globalsustainablehealthinstitute.com Read: The Wildatarian Diet by Teri Cochrane What You Eat is Turning Your Genes On and Off – Teri Cochrane – #646 The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jan 23, 2024

Meet the man who’s making leaps forward in functional movement training. Ben Patrick (aka the Knees Over Toes Guy) went from chronic knee issues to becoming a dunking sensation with his remarkable 42-inch vertical leap. His journey led him to discover the unconventional “knees over toes” method. He now trains to reverse joint pain and defy aging. In this episode, Ben shares his three game-changing foundations of exercise. We look back at the history of backward walking, and talk about its benefits today. Ben gives us his best tips for strengthening and healing knees, calves, shins, hip flexors, and shoulders. We start from the ground up with fixes for feet and toes. Plus, we talk about the problem with most shoes. Today’s biggest takeaway is recognizing the connection between functional movement and longevity. Functional training is key to how long you live and how well you live. Whether you’re 18 and want to do parkour or you’re 80 and want to get up off the floor—or still do parkour—you’ll want to hear this one. (00:04:45) What’s Up With Knees Over Toes? (00:13:58) Strengthening Joints, Not Just Muscles (00:19:54) Starting Off on the Right Foot (00:28:21) Taking It Back to Basics (00:38:30) Will These Workouts Help or Hurt Your Joints? (00:45:09) Fixes From the Toes Up (00:53:48) How To Have Healthy Hip Flexors (01:00:33) Healthy Movement Patterns for Life (01:03:03:) Secrets To Shoulder Healing (01:05:50) Marketing That Actually Helps People Sponsors Quantum Upgrade | Go to QuantumUpgrade.io/Dave for a 7-day free trial Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: atgonlinecoaching.com ATG Equipment: atgequipment.com Instagram: @kneesovertoesguy YouTube: @TheKneesovertoesguy TikTok: @kneesovertoesguy Biohacking Conference: biohackingconference.com The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jan 18, 2024

Today, we're learning how to Biohack like a Woman. And trust me, it's not about counting calories or giving up your favorite foods; it's a whole new paradigm. I'm thrilled to introduce you to our incredible guest today, someone I've had the privilege of working with for several years—Aggie Lal aka Biohacking Bestie. Aggie is not your average biohacker; she's a public figure, bestselling author, health coach and a TEDx Speaker. She's been featured on TV and started the renowned Travel her Shoes blog over a decade ago, eventually leading her down the path of biohacking after realizing the toll constant travel can take on your health. Aggie's journey has led her to establish the Higher Self Academy, where she offers courses to help individuals, especially women, personalize their biohacking journeys. She's also the host of the Biohacking Bestie podcast—make sure to check out our recent conversation on her show. I love the work Aggie’s doing so much, that I even wrote the foreword for her groundbreaking new book, Biohack Like a Woman, which is all about revolutionizing weight loss and biohacking specifically tailored for women. In today's episode, we delve into topics like fertility, understanding perimenopause, and exploring distinct biohacking recommendations for men and women. Aggie and I discuss why women must honor their cycle when trying new practices and the common challenges women face when under-eating calories and exercising. Plus, Aggie shares her valuable nutritional advice for women, including protein intake per meal. (00:02:01) Aggie’s Mission To Empower Women Through Biohacking (00:10:46) Addressing Stress Response Capacity & The Importance of Rest & Recovery (00:21:12) Biohacking Your Cycle, Fertility & Birth Control (00:34:55) Nourishing Women: Understanding the Impact of Caloric Deficiency & Exercise (00:44:53) Embracing New Relationship Dynamics & Women’s Innate Power (00:54:24) How Biohacking Is Disrupting Mainstream Medicine (00:59:21) Nutritional Recommendations for Women Sponsors BiOptimizers Magnesium Breakthrough | Go to bioptimizers.com/dave for 10% off your order. ARMRA | Try it out for yourself at tryarmra.com . Use code DAVE to get 15% off your first order. Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Read: Biohack Like a Woman Biohacking Bestie: biohackingbestie.com Higher Self Academy: higherselfacademy.co Instagram: @aggie Instagram: @biohackingbestie YouTube: @biohackingbestie TikTok: @biohackingbestie Biohacking Bestie Podcast: biohackingbestie.com/pages/biohacking-bestie-podcast The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jan 16, 2024

Today’s very special episode comes from inside Kimbal Musk’s kitchen, where I get a hands-on look at his passion for cooking, community, and regenerative farming. Kimbal Musk is a South African restaurateur, chef, entrepreneur and a board member at Tesla Inc. and SpaceX, companies led by his brother, Elon Musk. Outside of the tech space, Kimbal is the force behind The Kitchen Restaurant Group and co-founder and chairman of Big Green, where he's pioneering outdoor classroom Learning Gardens in schools nationwide. Additionally, Kimbal co-founded Square Roots, an innovative urban farming venture utilizing hydroponic, climate-controlled shipping containers. In our last interview at his newly opened restaurant, The Kitchen, we explored the intersection of technology, regenerative agriculture, and grass-fed cuisine. Today, we unpack Kimbal's passion for food and community. Seriously, we’re not just chatting about technology and longevity here—Kimbal teaches me how best to prepare, serve, and enjoy grass fed steak to perfection. During this live tutorial, we talk about how the energy you put into preparing your food really does impact how it tastes, and his unique perspective on innovation and leadership, gained from working closely with his brother Elon and the teams at Tesla and SpaceX. Then, we explore the highlights of his new cookbook, The Kitchen Cookbook: Cooking for Your Community, a treasure trove of real-food recipes accompanied by easy to follow video tutorials. It’s an incredibly valuable resource for anyone that’s interested in bringing more realness to their food prep and diet. (00:02:14) Embracing Community Through Food (00:18:33) Teaching Kids About Regenerative Farming With Big Green (00:28:56) Try the Kitchen Cookbook for Better Family Meals (00:38:52) Kimbal Musk on Psychedelics: In or Out? (00:43:06) Cooking for Elon Musk (00:47:27) Learn How To Prep & Cook a Beautiful Grass-Fed Steak Live (00:59:22) Kitchen Thoughts on Longevity & Death (01:04:12) Exploring the Link Between Quality Fats & Testosterone Sponsors Apollo Neuro Wearable | Head to apolloneuro.com to save 15% on your Apollo wearable. CAROL Bike | Save $250 on CAROL Bike until January 15th with code DAVE at carolbike.com . Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Organic Revolution: Kimbal Musk’s Mission to Take Down Big Food # 504 Big Green: biggreen.org Read: The Kitchen Cookbook by Kimbal Musk The Kitchen: thekitchen.com Read: Elon Musk by Walter Isaacson The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jan 11, 2024

Today’s guest is not a scientist but a true visionary. Gary Vaynerchuk (aka Gary Vee), is a self-made entrepreneur and digital marketing pioneer. He started his business journey with a lemonade stand at age seven. Now, he’s a prolific content creator, best-selling author, and the co-founder of the massive digital agency VaynerMedia. What I love about Gary is that he leads with integrity, optimism, and, above all, gratitude. He’s a guy of wisdom, not just business—and that’s an important element of what The Human Upgrade is all about. In today’s episode, we explore how entrepreneurship has changed since Gary and I started. We get into how to grow a business in 2024 and Gary’s advice for anyone starting out. His secret to success will surprise you. We talk a lot about gratitude, and how that lens has shaped Gary’s long career and kept him from burning out. Gary also shares his perspective on today’s social media landscape, the importance of kind candor, and why we should look to our elders. No doubt, listening to Gary will inspire you to go after your passions and try that thing you’ve been putting off. In Gary’s words, your happiness is worth fighting for! (00:02:01) Redefining Success as an Entrepreneur (00:07:02) How Gary’s Upbringing Impacted His Success (00:10:32) The Truth About Social Media in 2024 (00:14:49) Is Everyone Just Copying Each Other? (00:18:50) Gratitude As the Antidote for Burnout (00:24:11) Championing Wisdom Instead of Youth (00:29:21) Prioritizing Joy Over Riches (00:38:02) Recognizing the Importance of Kind Candor (00:43:08) Reframing Relationships & the Perspectives You Engage With (00:47:17) Leading With Gratitude, Not Fear Sponsor 40 Years of Zen | Go to 40yearsofzen.com/dave to receive an exclusive offer for podcast listeners. Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: garyvaynerchuk.com Instagram: @garyvee TikTok: @garyvee Facebook: Gary Vaynerchuk YouTube: @garyvee X: @garyvee Discord: VeeFriends The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jan 9, 2024

I'm excited to welcome back Dr. Steven Gundry to The Human Upgrade for his sixth appearance, a tribute to his remarkable insights and ongoing research. Dr. Gundry, a true pioneer, is renowned for his books like "The Plant Paradox" and his groundbreaking work on lectins, changing how we understand our body's reaction to food. He's also a top cardiothoracic surgeon and a leader in robotic cardiac surgery, with over two decades of research into the microbiome, using diet and nutrition as key treatment tools. His book, "Unlocking the Keto Code," and his wellness line, GundryMD, have made significant impacts in health and nutrition. In this episode, we dive into cutting-edge research from his new book “Gut Check.” Dr. Gundry discusses the microbiome's connection to disease, and gut health's role in hormone regulation, crucial for mental health during menopause. He'll also share insights on dietary choices, the truth about parasites, and nicotine's unexpected role in longevity. Dr. Gundry's transformative wisdom bridges traditional and alternative medicine. A big thank you to him for another enlightening visit. Thanks for joining us on this journey of discovery! (00:00:22) The Latest Research on How To Reverse Disease (00:10:16) The Link Between Leaky Gut & Gluten (00:16:50) Debunking Blue Zones (00:19:28) What Meat Products You Should Eat & Avoid (00:23:43) The Latest Data on New 5GC, 5AC & Fermented Meat (00:34:27) The Real Issue with Oxalates & How To Boost Your Defenses (00:41:33) How the Microbiome Influences Hormones & Menopause (00:48:10) What Foods Have the Highest Risk for Parasites According to Dr. Gundry (00:55:11) Benefits & Risks of Berberine (00:58:21) The Surprising Truth About Nicotine & Longevity (01:09:11) The Downside to Too Much Olive Oil Sponsors ARMRA | Visit tryarmra.com and use the code DAVE to get 15% off your first order. Leela Q | Visit leelaq.com/dave and get a 10% discount on LeelaQ products. Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Read: Gut Check by Dr. Steven Gundry Website: drgundry.com Podcast: The Dr. Gundry Podcast Keto Gets an Upgrade – Dr. Steven Gundry #912 How to Identify Your Energy Blockers and Beat Fatigue – Dr. Steven Gundry with Dave Asprey – #803 How Foods are Harming Your Kids – Steven Gundry, M.D. – #649 Healthy Aging Begins and Ends in the Gut – Dr. Steven Gundry #604 How Nutrition Can Reverse Disease and the Impact of Lectins – Dr. Steven Gundry – #417 The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jan 5, 2024

On today’s Upgrade Spotlight episode, we’re talking all about NAD+. In the biohacking world, everyone and their mother has heard of NMN and NAD+, but there’s more to it than meets the eye. To get into the nitty gritty of NAD+, we’re joined by Dr. Gregory Kelly, a naturopathic physician and the lead product formulator at Neurohacker Collective, also known as Qualia. I’m an advisor to the company, and they do fantastic and innovative work in the longevity space. Their NAD+ supplement is a quantum leap in biohacking and a no-brainer to add to your stack. In today’s episode, Dr. Kelly explains what NAD is and why it’s essential for longevity, cognition, energy levels, and athletic performance. We talk about the differences between NR, NMN, and Niacinamide. We also explore the most efficient way to get NAD. Is an IV worth the money or will supplements give you more bang for your buck? Plus, Dr. Kelly breaks down exactly what’s included—and not included—in the Qualia NAD+ formula. I’ve been a major proponent of NAD for more than 10 years, but I don’t like to spend all my time and money getting it. If you feel the same, you’re going to want to tune into this episode. (00:01:55) What Is NAD & Why Do We Care? (00:06:19) The Most Efficient Way To Get NAD (00:09:55) Sirtuin’s Superpowers (00:14:42) The Qualia NAD+ Formula (00:22:37) The Buzz on Coffee Berry (00:25:53) When Is the Best Time To Take NAD+? (00:30:01) NAD+ in Clinical Trials (00:34:16) What’s NOT in the Qualia Supplement (00:38:02) A Quantum Leap for Biohacking Episode Sponsor Neurohacker | Boost YOUR NAD+ up to 50%* + GET 50% OFF go to neurohacker.com/DAVENAD . Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Visit neurohacker.com/davenad to save 50% on Qualia NAD+ by Neurohacker Neurohacker Collective: neurohacker.com Neurohacker Collective Instagram: @neurohacker Linkedin: Gregory Kelly The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jan 4, 2024

Today, we take a look into the mindset and habits of successful entrepreneurs and mastering the art of organization for success, topics that today’s guest has totally mastered. Jesse Itzler has an impressive background with a bachelor's degree from American University and a further degree in justice, law, and society. His resume as an entrepreneur is also quite impressive, co-founding Marquis Jet, the world's largest private jet card company, which was later sold to Berkshire Hathaway/NetJets. Beyond this, he's partnered with Zico coconut water, selling it to The Coca-Cola Company, and has ventured into the music industry, co-writing Billboard Top 100 hits and co-founding Alphabet City Sports Records. Jesse is also an acclaimed triathlete and author, with his book, Living with a Seal, becoming a New York Times bestseller. As we step into the early days of 2024, this episode is all about providing you with clear, direct methods to upgrade your life across various facets—work, fitness, and personal development. Tune in as I compare and contrast my organizational methods with Jesse's, the goal being to introduce you to strategies that resonate with you and align with your personality. You'll gain insights into how Jesse efficiently prioritizes his calendar and the skills needed to outperform competition when you’re starting out in business. We also explore habits and tools for staying physically and mentally young, our favorite biohacks, my personal excitement in the field of longevity, and ways to structure your life for maximum return on investment, both in terms of monetary success and happiness. While our methods differ in some areas, our objective is the same: to live a life with minimal regrets, whether you reach 80 or 180 years old. Join us as we discuss the habits of successful entrepreneurs—both from our experience and learning from others at the top of their game—and discover practical ways to implement these lessons into your life. (00:00:20) The Secret to Jesse’s Success in Business & Triathlons (00:05:10) How Jesse Organizes His Life & Implements New Habits (00:22:49) Structuring Support Systems & Early Hires (00:32:41) Lessons From Living With a Seal & Monks (00:48:19) What Biohacks Dave Is Most Excited About (00:54:21) How To Organize Your Time Efficiently (01:01:54) The Mindset & Habits of Successful Entrepreneurs (01:10:34) The Recipe for a Fulfilling Life (01:18:46) Dave’s Top Tools for Longevity Sponsor: https://www.viome.com/dave to save $150 full body intelligence test. Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: jesseitzler.com Instagram: @jesseitzler TikTok: @jesseitzler YouTube: Jesse Itzler Linkedin: Jesse Itzler The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jan 2, 2024

Dr. Anthony Youn, aka “America’s Holistic Plastic Surgeon,” is an expert in your face. He joins us to answer some burning questions… Can plastic surgery actually be holistic? Can you turn back the clock without going under the knife? And… What work should I get done to my face? Today, we’re talking all about how to hack your face and save your skin. Dr. Youn is a nationally-recognized, board-certified plastic surgeon. He’s the most followed plastic surgeon on social media and a TikTok star. He’s the author of The Age Fix, In Stitches, and Playing God. His new book, Younger For Life, is a complete holistic guide to anti-aging using a process he coined called Autojuvenation. In today’s episode, we get into what Autojuvenation is, and how it helps you look younger without surgery—a surgeon who wants to help you avoid surgery! We talk about blending biohacking and cosmetics, natural vs. medical-grade skincare, collagen peptides, treating hair loss, and whether sunscreen causes or prevents cancer. Dr. Youn also tells us the dumbest things that both men and women do to their faces—and how to avoid them. Let’s face it, many of us want to look younger. This conversation is a fascinating look at how to approach aesthetics from a biohacker’s perspective. (00:01:55) Is There Such Thing As Holistic Plastic Surgery? (00:05:12) Natural vs. Medical-Grade Skincare (00:09:36) Holistic Alternatives That Traditional Physicians Don’t Know (00:16:47) Does Topical Collagen Work? (00:19:45) What Cosmetic Work Should Dave Have Done? (00:25:20) Blending Biohacking & Cosmetics (00:30:38) The Dumbest Things Men Do to Their Skin (00:35:37) Is Sunscreen Preventing or Causing Cancer? (00:38:33) The Dumbest Things Women Do to Their Skin (00:43:54) The Hair-Raising Effects of Hair Loss (00:52:35) Additional Skin Biohacks from a Pro Sponsors: Tru Kava https://trukava.com/ use code Dave15 One Skin: https://www.oneskin.co/ use code Upgrade15 Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: dryoun.com Pre-order: Younger For Life (over $100 value of free bonuses) TikTok: @doctoryoun Instagram: @tonyyounmd YouTube: @DoctorYoun Podcast: The Holistic Plastic Surgery Show The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Dec 28, 2023

Get ready for this important download on a fascinating biohacking compound you haven’t heard me talk about before: Urolithin A. It’s a postbiotic that supports the mitochondria, and it’s backed by impressive studies on longevity, anti-cancer effects, cognitive function, and muscle strength. In fact, this compound has earned a place in my permanent stack—which you know isn’t easy to pull off. Today, I chat with Dr. Dominic Denk, who’s done some of the original research on Urolithin A and the company that makes it, Timeline Nutrition powered by Mitopure. Dr. Denk works as a physician in the Department of Internal Medicine at University Hospital Frankfurt. Dr. Denk breaks down what Urolithin A is and how it impacts aging and cancer prevention—answering questions on when, how, and why to take Mitopure—before we delve into the powers of mitochondria, how to have more energy production in your cells, and the relationship between energy production and cancer. We also talk T cells, autoimmunity, and inflammation. Plus, we get into the differences in healthcare and pharmaceutical overreach in the U.S. and Germany. Tune in to uncover the latest life-changing compound—and find out what it will do for your heaviest lift in the gym, your cognition before your next big meeting, and to reverse aging over time. (00:03:31) Understanding Urolithin A (00:08:43) Genetic vs. Mitochondrial Cancer (00:14:48) Getting to the Root of Autoimmunity (00:21:19) Strong Evidence on Muscle Strength (00:23:59) Does Cancer Hate Americans? (00:27:59) Why Do We Age? (00:31:35) The Best Studied Compound You’re Not Taking (00:33:02) Talking T Cells (00:36:22) Healthcare in Germany vs. The U.S. (00:43:31) Urolithin A & Hot/Cold Therapies (00:45:55) Tripling Down on mTOR (00:52:05) Are There Downsides to Urolithin A? Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Timeline Nutrition: timelinenutrition.com and use code DAVE to save 10%. After January 1st, 2024, TimelineNutrition.com/dave for 30% discount. Mitopure: mitopure.com X: @DomDenkMD Linkedin: Dr.med. Dominic Denk The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Dec 26, 2023

In this special end-of-year "best of" episode, you'll learn the Top 10 hallmarks of aging, the role of functional medicine in restoring and reversing aging, and the many practical ways you can promote your own longevity. Mark Hyman, M.D., joins Dave in Austin to talk all things longevity. Driven by his desire for a healthier, longer life for himself and others, Dr. Mark immersed himself in the latest scientific research on aging and longevity. Through his findings, he realized that the body has an incredible built-in healing system that can be activated through understanding the emerging science of longevity. He also managed to reduce his biological age by 20 years effectively. He consistently tackles the topic of inflammation and its impact on aging—or “Inflammaging” as he calls it. “The body only has so many ways to say ouch,” Dr. Mark says. “You have pain. You have inflammation. You have certain things that happen that create all these symptoms, but there're these common roots. So, inflammation is this common root that seems to accelerate as we get older. So, we can measure biomarkers of inflammation that are highly predictive of mortality.” This conversation covers many components of aging, like metabolic flexibility and resilience, mTor, meat- and plant-based protein, nutrition, environmental allergies and food sensitivities, histamine, autophagy, fasting, DEXA scans, and much more! In his book, " Young Forever: The Secrets to Living Your Longest, Healthiest Life ,” Dr. Mark: shares the knowledge of how to unlock the causes of accelerated aging and treat it as a reversible disease. gives you practical tips for daily habits that will increase your energy and performance. teaches you why you age and what it really takes to live a longer, more vibrant life. Watch this episode on YouTube ! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Dec 21, 2023

In this episode of The Human Upgrade you’ll meet Robert Waldinger, M.D., who leads an extraordinary scientific study on happiness that’s still going strong after eight decades. The study set out to understand human health by what made people thrive . Since 1938, the Harvard Study of Adult Development has tracked two groups of men and their families with the goal of discovering what really makes for a good life. Along the way, thousands of questions were asked, and hundreds of measurements were taken—from brain scans to blood work. Three strong themes emerged from the study: Social connections are really good for you. Loneliness kills. It’s the quality of your close relationships that matters. Good close relationships don’t just protect your body , they protect your brain . Dr. Waldinger combined those lifelong case studies with modern psychological research in his new book, co-authored with Marc Schulz, Ph.D., “ The Good Life: Lessons from the World's Longest Scientific Study of Happiness ." This discussion gives you real-life tools to hack your happiness. You’ll learn things like: how relationships improve your physical, mental and emotional health. (More than you know!) how to evaluate the effect of your relationships on your well-being. (Don’t be dragged down.) what social fitness is and how to practice it. (Yes, it’s a flex.) ways to enliven and energize your relationships. (Energy totally matters.) why casual and work relationships matter more than you think. (A surprisingly big contribution.) Watch this episode on YouTube ! Don’t Miss This! Dr. Waldinger’s TEDtalk about the study is one of TED’s Top 10 episodes and viewed more than 43 million times. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Dec 19, 2023

This episode is a deep dive into the heart of modern fitness, led by one of its most influential figures. Joining me today is Lavinia Errico, the visionary co-founder of Equinox Fitness Clubs. Lavinia isn't just a pioneer in the fitness industry, she's a passionate advocate for a life that's healthier, more fulfilled, balanced, and brimming with joy. She's dedicated to helping others achieve these same goals, inspiring people to delve into self-awareness and embrace transformative journeys. With her belief in enjoying the journey and embracing the process, Lavinia has shaped not just her own life but the lives of countless others towards seeing, feeling, and living remarkable results. Today, you’ll hear about how Lavinia's career in fitness and biohacking began with the birth of the modern fitness movement and Equinox as she shares challenges and triumphs of starting a fitness revolution in 1980s New York. You’ll also learn about the unique ethos that set Equinox apart and how building a business with family shaped its upward trajectory. This conversation is threaded with insight into the life of an entrepreneur, the realities of being a CEO, and how Lavinia intuitively balanced her professional journey with motherhood. Lastly, you’ll get a taste of Lavinia's wellness rituals, her philosophy as a lifelong learner, and her exciting new chapter with MOVEJOY, aimed at creating a more stress-free, joyous workout experience for everyone. (00:01:41) Laying the Foundation of Equinox (00:10:44) Finding the Joy of Movement (00:18:56) Advice for Women in Business (00:24:51) The Honest Cost of Being an Entrepreneur & CEO (00:32:14) Wellness Rituals & Being a Student of Life (00:44:47) Introducing Move Joy (00:55:27) Shifting the Why Behind Movement Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: movejoy.life Instagram: @laviniajoy LinkedIn: Lavinia Errico The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Dec 14, 2023

Today is a long-awaited show with none other than Bryan Johnson, an entrepreneur, venture capitalist, author, and professional rejuvenation athlete on a mission to discover the next evolution of humankind. While Bryan is well known in the longevity space, I’ve been a fan of his work for years because of his neuroscience background. Bryan started a company called Kernel, which makes devices that monitor and record brain activity. Kernel uses what I would call the most comprehensive way of looking at the human brain ever. He is the founder of OS Fund and Braintree, and he spearheads Project Blueprint, an anti-aging experiment where he’s spent multiple years and millions of dollars developing an algorithm to live longer. In today’s wide-ranging talk, we discuss the future of optimizing our brains with AI—delving into all things biohacking and longevity while exploring complicated questions like… Can you die of loneliness? And… Are your critics making you old? Plus, we talk testosterone—an often triggering topic, but an essential conversation. Bryan shares his perspective on why he would rather be respected by people in the 25th century than understood now. Stick around for his surprising takes on olive oil, body hair, and saunas. (00:59) Biohacking The Brain (05:34) Are Your Critics Making You Old? (12:52) What Makes Bryan Tick (20:09) The Longevity-Loneliness Connection (28:27) Accounting For Bio Individuality in Health Protocols (39:09) Does Having a Partner Help You Live Longer? (47:59) Olive Oil vs. Saturated Fats (54:39) Talking Testosterone (01:07:52) Expanding Consciousness with Psychedelics (01:12:06) Questions from the Live Audience Sponsor: Try Qualia NAD+ with an extra 15% off with code Dave15 . Resources: Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: protocol.bryanjohnson.com Kernel: kernel.com Read: Don’t Die by Zero Instagram: @bryanjohnson_ YouTube: Bryan Johnson Linkedin: Bryan Johnson The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Dec 12, 2023

Coming to you live from Austin, Texas, I can’t wait for you to meet Dan Freed—a man who’s journeyed from the hot kitchen of high-end cooking to the frontier of brain improvement. Dan’s the founder and CEO of Thesis, a company that's revolutionizing the way we think about our brain's potential, and his journey is one of resilience and innovation. Picture this… A kid struggling with focus throughout childhood, he drops out of high school and claws his way up in the ruthless restaurant industry to become a saucier in a three-star Michelin kitchen. But the real twist comes when Dan, grappling with burnout, stumbles upon cognitive performance supplements. This discovery didn't just change his mental game, it transformed his entire life. Fast forward through degrees from Yale and INSEAD, and you have the Dan that sits down for this interview—committed to helping others harness their brainpower to the fullest. We get into the nitty gritty of nootropics and the supplement industry, talking about how Dan's fight with burnout and learning challenges led to the birth of Thesis Nootropics. We share tips on adapting human biology to our modern world, discuss the thorny issues of regulation and quality in the supplement industry, and explain how Thesis uses a unique combined approach of customizing nootropics and expert support for their customers. We round it all off with a look at the remarkable, results-driven formulas that Thesis offers, and how focus is the key to unlocking our greatest potential. Dan's story is a living proof that sometimes, a couple of stumbles can lead to an incredible leap forward, thanks to some conscious action. That’s the kind of journey we all can learn something from. (00:02:14) How Burnout & Learning Challenges Inspired Thesis Nootropics (00:19:15) Is Using Nootropics Cheating? (00:25:37) Tips for Adapting Human Biology to the Modern World (00:32:33) How Thesis Is Customizing Nootropics (00:40:59) Tips for Supporting Your Body’s Homeostasis While Taking a Stimulant (00:46:33) Dave Rings the Alarm on Formulating With Vitamin B6 (00:50:53) Regulation & Quality Concerns in the Supplement Industry (00:57:41) Key Ingredients in Thesis’ Clarity & Logic Formulas That Drive Real Results (01:04:28) Unlocking Your Potential Through the Power of Focus Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: takethesis.com and use code “Asprey” for a 10% off all Thesis products. Instagram: @takethesis Facebook: Take Thesis The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Dec 7, 2023

Cynthia Thurlow joins the show to talk about how intermittent fasting can help women change their body, metabolic system and brain function. She has tips for women at all stages: from active menstrual cycles to perimenopause to menopause. Cynthia is a Johns Hopkins-trained nurse practitioner and functional nutritionist founded and serves as CEO of Everyday Wellness Project. She holds a Master of Science degree in Nursing and Functional Nutrition certifications with advanced trainings in Endocrinology and Gastroenterology. Her career in healthcare includes nearly 20 years of emergency medicine and cardiology experience. She brings a broad perspective when working with women to improve the state of their health. “I really start from a foundational level talking to women about fasting,” Cynthia says. “It's really honoring our own unique physiology. It's leaning into that menstrual cycle. It's leaning into the lifestyle piece that so much of us forget to talk about with our patients, our sleep quality, stress management, anti-inflammatory nutrition, our exercise quality, our connection with nature, all of which are critically important.” She also addresses diet dogma that frustratingly persists, even with established and emerging science about the benefits of intermittent fasting. She tackles this outdated dogma (and a lot more!) in her new book, “ Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging .” “[Intermittent fasting] restores our intrinsic rhythms, burns fat, regenerates our health right down to the cellular level, and stabilizes our hormones,” Cynthia says in her book. “In turn, we are less likely to develop obesity, diabetes, vascular diseases, and autoimmune disorders.” At the end of this conversation, you’ll have the tools to decide if intermittent fasting is the right choice for the state of your own health. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Dec 5, 2023

Dive into a captivating exploration of human biology and connection—erotic blueprints. Discover four primal drivers: fear, food, friends, and fertility, with a unique focus on fertility in this episode. Miss Jaiya, a leader in somatic sexology, sheds light on the intimate realm of human relationships and pleasure. As an award-winning somatic sexologist and creator of The Erotic Blueprints® Framework, Jaiya dedicates her expertise to helping people understand their unique erotic blueprints and their impact on intimate lives. Her latest book, "Your Blueprint for Pleasure," offers invaluable insights into a revolutionary language for bedroom communication and sexual vitality. This episode delves into the concept of erotic blueprints, Jaiya's research, and the unique paths to turn-on and blissful gratification for each individual. This conversation aims to understand people's true desires and needs in intimate relationships, free from taboos or judgment. Highlighting that sex and intimacy are vital for well-being, just like food and breathing, this discussion includes personal experiences and emphasizes the importance of vulnerability. Learn how understanding your erotic blueprint can enhance connections and satisfaction in the bedroom. Whether seeking to enrich intimate life or deepen understanding of human biology and connection, this episode offers valuable insights for everyone. (01:34) Reconciling Spirituality & Sexuality: Jaiya’s Sexual Empowerment Journey (12:00) Why Sex Is the New Frontier of Personal Growth & Biohacking (15:25) Jaiya’s Wildest Energetically Erotic Experience (21:35) Conscious Kink & Blending Psychedelics With Sexuality (30:52) Your Pleasure Blueprint: Defining the 5 Erotic Types (34:55) Discovering the Erotic Blueprint Through Her Own Relationship (40:01) Addressing the Intimacy Issue in Our World & Sending Love Through the Field (46:44) Confronting the Taboo of Pleasure (52:11) Mastering Energetic Sexuality & Orgasms (01:01:48) Risks in Using Psychedelics for Creation Energy (01:06:49) The Dark Side of Spiritual Ecstatic Altered States & How To Protect Your Field Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: blueprintbreakthrough.com Read: Your Blueprint For Pleasure by Jaiya Instagram: @missjaiya The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 30, 2023

I am excited to chat with a longtime friend who is a fellow expert in how to make your brain work better. Jim Kwik is an absolute wizard when it comes to maximizing your brain's potential. We go way back, over a decade, and I can vouch for his incredible expertise in the realm of cognitive enhancement. He also has just released an expanded addition to his best-selling book, Limitless, where he delves deep into topics that both he and I hold near and dear—nootropics and brain enhancement. Jim Kwik is a widely recognized world expert in memory improvement, brain function, and accelerated learning. After a childhood brain injury left him learning-challenged, Kwik created strategies to dramatically enhance his mental performance. He has since dedicated his life to helping others unleash their true genius. In addition to being an author, he serves as ultra-informed host of the top education training podcast: Kwik Brain. His mission: No brain left behind. From overcoming childhood adversity and turning it into a superpower, to the secrets behind better memory and accelerated learning, this episode is full of tools for enhancing cognitive function. Plus, we explore the groundbreaking concepts Jim covers in Limitless: Expanded, including the use of nootropics to elevate brain function, his favorite daily biohacking techniques and brain exercises, and how identifying your brain animal can enhance your self awareness and therefore potential. (00:01:44) Jim Kwik’s Inspiring Brain Health Journey (00:10:18) Top 5 Most Recommended Nootropics (00:16:49) Supplements for Brain Health & Longevity (00:23:32) Jim’s Biohacking Must-Haves & Daily Routine (00:29:53) Healing the Emotional Thread & Embracing Post-Traumatic Growth (00:36:03) Top Exercises for Your Brain (00:47:41) C.O.D.E. – Understanding Your Brain Animal (Cognitive Type) (00:55:57) Leveraging Self-Awareness as a Superpower Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: jimkwik.com Read: Limitless Expanded by Jim Kwik Podcast: Kwik Brain Instagram: @jimkwik YouTube: Jim Kwik LinkedIn: Jim Kwik The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 28, 2023

Today’s guest is nothing short of a modern-day Willy Wonka for Generation X. He built a billion-dollar ecstasy business in the '90s and did not end up behind bars. That's a story you've got to hear. Our guest today, Shaahin Cheyene, not only dabbled in the wild world of herbal ecstasy but also managed to stay out of trouble despite being investigated by seven attorney generals. And get this, he wasn't even 18 when he pulled off these daring feats. Shaahin's story doesn't stop there. Since those days, he's become an Amazon expert, successfully selling nootropics and a variety of other products on the platform. He's also a filmmaker and author of the book, “Billion: How I Became the King of the Thrill Pill Cult.” From Fleeing Iran at the age of five to being homeless and living out of his car, Shaahin's journey is nothing short of remarkable. It's safe to say he's one of the most interesting individuals I've had the pleasure of interviewing. We dive into Shaahin's captivating journey, exploring his transformation from a young criminal to a thriving entrepreneur. You’ll also learn about what went into his groundbreaking herbal ecstasy formula and how he managed to get his business off the ground. Along the way, we discuss the challenges of navigating the bureaucracy of big government, the importance of seeking help when needed, and the valuable lessons Shaahin learned from building and eventually exiting his herbal ecstasy empire. We also delve into how he managed to run a nine-figure company selling on Amazon, the mindset benefits of Brazilian jiu-jitsu training, the power of curating ideas, and how you can strategically leverage podcasts as an entrepreneur. Join us on a ride you won't want to miss. (01:47) How Shaahin Became the King of the Thrill Pill Cult (07:36) Formulating Herbal Ecstasy & Building a Million-Dollar Business (16:34) Navigating the Bureaucracy of Big Government (28:04) Pro Tip for Entrepreneurs: Why It’s Important To Ask for Help (32:09) What Cheyene Learned From Building & Exiting His Business (37:29) What To Do When You Make Your First Million (39:21) Scaling a 9-Figure Company Selling on Amazon (45:05) Lessons From Martial Arts & Our Bets on Musk vs Zuckerberg (54:03) The Tactical Advantage of Podcasting & Being a Curator of Ideas (01:03:30) Media Training 101 Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: shaahincheyenne.com PodcastCola: podcastcola.com Instagram: @shaahincheyene Podcast: Business Story of the Week LinkedIn: Shaahin Cheyene The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 21, 2023

I’ve been eagerly looking forward to this conversation with a dear friend and a true luminary in the realm of relationships and personal development, John Gray. for quite some time. You probably recognize his name as the author of the famous book, Men Are From Mars, Women Are From Venus. But what's especially exciting is how John has evolved his insights to address the changing dynamics between men and women in the modern world, as he highlighted in his 2020 book, Beyond Mars and Venus: Relationship Skills for Today's Complex World. Now, why is this episode a must-listen? Well, John isn't just a relationship expert; he's also a seasoned biohacker who understands the profound impact of our environment – including relationships – on our hormones, happiness, and dopamine levels. In essence, he's been biohacking before it even had a name. With decades of wisdom, he offers invaluable insights into navigating the complexities of male-female relationships in today's world. Delve into the fundamental differences between men and women, the importance of appreciation in relationships, what truly motivates men, and practical tips on boosting testosterone and managing emotions. We also explore how men and women process feelings differently, the art of setting boundaries, and the language of love as the language of hormones. Get ready for a masterclass in understanding the dynamics of modern relationships and how to create lasting happiness. (00:59) Understanding Fundamental Differences Between Men & Women (04:38) Do Men Exist To Make Women Happy? (06:32) Exploring What Drives & Motivates Men (11:09) How To Boost Testosterone & Navigate Emotions (19:14) Why Men Disconnect When Talking About Feelings (30:22) How Men Can Help Women Come Back Into Balance (39:17) Setting Boundaries & Working on Your Relationship (49:41) Advice for Women for How To Talk About Their Feelings With Their Partner (01:02:22) Why the Language of Love Is the Language of Hormones (01:05:48) What Women Need in a Relationship (01:13:07) The Defense Against Attacks on Your Reputation (01:17:49) Techniques for Processing Emotions (01:25:32) Thoughts on Estrogen Receptor Degraders (01:31:48) What Masturbation Does to Men vs. Women (01:37:42) Advice for Couples Not Having Sex Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: marsvenus.com Read: Beyond Venus and Mars by John Gray Instagram: @johngraymarsvenus_official LinkedIn: linkedin.com/in/marsvenus The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 16, 2023

Today's episode delves deeper into the captivating world of quantum field therapy and the power of intention, featuring the renowned Lynne McTaggart. Lynne, known for her books "The Power of Eight," and “The Field” offers groundbreaking insights into the profound impact of group intention. The discussion unravels the significance of the number 8, explores the mechanics behind Lynne's intention experiments, and examines the profound effects of healing and connection on our being. The conversation extends to the transformative power of expanding connection beyond the individual, the latest scientific developments supporting Lynne's theories, and the exciting potential of new technologies in quantum healing. The episode covers the role of intention in healing polarized communities and intriguing phenomena, such as The Simpsons' seemingly magical foresight. Get ready for a thought-provoking journey with Lynne McTaggart that promises to expand horizons, challenge beliefs, and inspire exploration into the uncharted territories of consciousness and intention. (03:01) What Is Quantum Field Therapy? (06:47) The Power of Eight (16:23) Inside the Power of Eight Experiments (19:40) How Healing & Connection Bring About States of Oneness (30:12) What Happens When You Expand the Group Beyond Eight (34:29) Evolving Our Understanding With the Latest Science (41:30) How New Modalities Support Lynne’s Findings (49:21) Lynne’s Measurement of Success: Stories of Real World Impact (56:44) Joining a Power of Eight Group or Intention Experiment (01:01:45) Healing Polarized Communities Using Altruistic Intention (01:09:14) What Technologies Can Push Boundaries Further? (01:16:15) How Did The Simpsons Magically Predict the Future? Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: lynnemctaggart.com Read: The Power of Eight by Lynne McTaggart YouTube: Lynne McTaggart Instagram: @lynnemctaggartofficial The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 14, 2023

How about we have a conversation with one of the most spiritually influential living people on earth? Yes, you heard that right! Today's guest was bestowed with this honor by Watkins MindBodySpirit, and if that's not impressive enough, AgeNation awarded him a Life Achievement Award. Today, we have the incredible privilege of sitting down with a true luminary in the world of spirituality, health, and resilience. His name is Mark Nepo, and he's not just an authority on spiritual matters and poetry; he's a living testament to the power of the human spirit. Mark is no stranger to adversity; he's a cancer survivor who has weathered life's storms and authored dozens of books, including The Book of Awakening and Surviving Storms: Finding the Strength to Meet Adversity. In essence, he's a true badass in resilience, and we're here to delve into the fusion of science, health, and spirituality with a master of all these realms. Mark's new book, Falling Down and Getting Up: Discovering Your Inner Resilience and Strength, is a profound exploration of how we can navigate life's challenges with acceptance and resilience. Throughout our conversation, we'll touch on the transformative impact of Mark's battle with cancer, the wisdom he's gleaned from our elders, the profound insights from indigenous healing traditions, and the incredible power of building resilience through pain. So, fasten your seatbelts, dear listeners, because this is a conversation that promises to touch your soul and leave you with valuable nuggets of wisdom for your own journey. (02:11) The Spiritual Impact of Overcoming Cancer in His Early 30s (10:05) How Our Beliefs Influence Our Reality (21:14) Navigating the Choice Between Love & Fear (27:11) The Invaluable Impact of Our Teachers & Healers (37:14) How To Face Failure & Build Resilience (47:44) Navigating the Deeper Teachers of Fear, Pain & Grief (01:01:36) Unlock Your Inner Wisdom Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: marknepo.com Read: Falling Down and Getting Up by Mark Nepo Instagram: @mark_nepo YouTube: Mark Nepo Facebook: @MarkNepo Oprah’s Review: oprah.com The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 9, 2023

Today, we delve deep into the world of cybernetics and the potential cyberpunk future with a true pioneer and a living legend in the field, Kevin Warwick. As an Emeritus professor at Coventry and Reading Universities, Kevin is celebrated as the world's first cyborg, earning him the moniker: Captain Cyborg. In this episode, we explore the incredible journey of Kevin Warwick, who became a cyborg over 25 years ago by implanting a chip in his arm, the size of a coin, enabling him to interact with the digital world in ways that were once unimaginable. But this isn't just about becoming a cyborg; it's about the potential, the risks, and the opportunities at the intersection of AI, robotics, and biomedical engineering. In doing so, we discuss the fascinating implications of merging humans with technology and how it can reshape our understanding of reality. Kevin's fearless exploration into the world of cybernetics is truly pioneering. He has been willing to take risks to expand our knowledge and possibilities as humans. Join us as we explore the profound implications of merging biology with technology, opening up new realms of human potential and perception, and what our future could hold as technology and research continues to progress. (00:01:43) The Realities of Pioneering Human Enhancement (00:10:05) Kevin’s Implantation Experiment & Research (00:18:10) Expanding Our Biological “Software” (00:24:39) How Far Is Too Far? Risk Tolerance for the Sake of Science (00:32:47) Exploring Human Enhancement Possibilities (00:39:21) Kevin’s Take on Longevity From His Brain Cell Research (00:43:13) Biohacking as an Entry Level Point Into Cyborgs (00:52:41) The Future of Cyborgs, Humans & Artificial Intelligence Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Podcast: Futures Podcast Read: I, Cyborg by Kevin Warwick Read: Artificial Intelligence: The Basics by Kevin Warwick Linkedin: Kevin Warwick The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 7, 2023

Today, we talk about one of my favorite biohacking topics: hormones. Starting way back before I first had kids, I’ve studied hormones as they relate to fertility – leading to the first of just a few books over the years, The Better Baby Book. And it's been an area of passion ever since because hormones also control your mood and your energy levels and your happiness. So I wanted to invite Dr. Francesca LeBlanc on the show – someone who has a very interesting blend of being a board certified chiropractor, a doctor of natural medicine, and a clinical nutritionist – to take us through the winding roads of food, lifestyle, and hormones in women. You could call this functional medicine, but Dr. Francesca LeBlanc has a unique spin on it. For years in her 20s and 30s, she suffered from brain fog, mood swings, irregular cycles, insomnia, depression, and anxiety. She spun her wheels with the allopathic model before discovering that the root cause of her symptoms could be traced back to hormone imbalances. Now, Dr. LeBlanc helps patients understand that it’s not all in their heads, and that they can live normal, symptom-free, joyful lives. In this conversation, we dive into her holistic healing journey, and how pioneers in the health biohacking space – including myself – guided and inspired her to create the hormone hierarchy; linking hormones to other chemicals in the brain. We explore what diet and lifestyle changes to make that can significantly improve not only how you feel but how your body functions, identify common deficiencies and inhibitors to healthy hormones, and share tools for stress management. (02:25) Painful Early Steps on Her Journey to Wellness (06:51) Basics of Hormones & Pregnancy (11:39) How Mold & Environmental Toxins Damage Hormones (21:03) Foods That Keep Your Hormones Healthy (27:06) The Hormone Hierarchy (34:44) Most Common Metals Impacting Women’s Hormones (40:33) Tools for Stress Management (48:03) Exploring Various Gateways to Holistic Health Hacking (58:32) Addressing Mineral Deficiencies Resources Sponsor: Go to www.DrinkLMNT.com/Dave and receive a free Sample Pack with your purchase. Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Instagram: @drfrancescaleblanc Website: labwellhealthcare.com The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 3, 2023

Today, let's delve into a topic often overlooked but crucial for our overall health: our skin. Over the past decade, I've started seeing our skin as more than just a protective layer; it's a major organ, just like our liver or heart. Its health goes beyond appearances – it profoundly influences our biology and well-being. Today, I welcome Carolina Reis Oliveira, the founder of OneSkin, a skin health company, to the show. She'll share exciting insights from recent research on specific peptides that can transform your skin's appearance and functionality. Here's the intriguing part: your skin's health closely links to your body's overall health. Inflamed or unhealthy skin signals underlying issues within your system. Conversely, improving your skin's health can reduce systemic inflammation and positively impact your organs. This revelation led me to discover a groundbreaking peptide called OS-01, found using advanced AI and novel compound-searching techniques. Carolina will explain how peptide OS-01 can reverse your skin’s biological age, the differences in their body, face, and eye formulas, the benefits of their mineral sunscreen to combat skin damage and reduce inflammation, and their new method to measure skin age. If you're considering investing in longevity, this episode is a game-changer. By tackling skin inflammation, you're not only enhancing your appearance but also reducing systemic inflammation, a double win. (00:02:30) Discovering OS-01 & How the Peptide Tackles Skin Aging (00:16:45) Inside the Different OneSkin Formulas for Face & Eyes (00:21:46) Boost the Effects of OS-01 Face With the OneSkin Cleanser (00:24:26) How & Where To Use the Body Lotion for Optimal Results (00:28:02) Exploring Potential OS-01 Systemic Effects (00:34:46) Finding the Right Dose With the OneSkin Formula (00:38:28) Benefits & Use Recommendations for Mineral Based Sunscreen (00:42:27) How OneSkin Activates Collagen & Hyaluronic Acid Production (00:44:43) The MolClock: Discovering a New Way To Measure Skin Aging Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: oneskin.co (use code upgrade15 for 15% off) Instagram: @oneskin.co The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 2, 2023

In this episode of The Human Upgrade my guest fits right into the podcast transition to The Human Upgrade because he gets into the grittiness of what humans can do to level themselves up. No. 1 New York Times bestselling author Robert Greene shares science-backed knowledge about human nature. You know you want to be more powerful, more in control and excellent at what you do. Robert’s insights help you do just that. He gives you actionable tips that help you unlock limitations you may be putting on yourself so you can move your life upward and forward. (Similar to something I like to tell my team is great momentum: “up and to the right.”) World leaders, military generals, business executives, philosophers, and hip-hop moguls alike revere Robert’s books. After writing about mastery and power for more than two decades, he’s now become a TikTok sensation and the universal truth for a new generation. He’s one of my favorite authors who’s profoundly influenced my own life and been on the podcast twice before. Both episodes are must listens: The 48 Laws of Power – #380 and The Laws of Human Nature – #575 . I asked him back to talk about his latest book: “ The Daily Laws: 366 Meditations on Power, Seduction, Mastery, Strategy, and Human Nature .” “In “The 48 Laws of Power,” I talk about deception and con artists,” Robert says. “But in The Laws of Human Nature, it's almost about self-deception, how we're con artists with ourselves, how we create an image of ourselves as being morally right, being a good person, being intelligent, being rational, being empathetic. Whereas in fact, we're usually quite far below that ideal. … Because your default position is to always look externally and blame other people.” In “The Daily Laws,” he distills the best of his previous books and never-before-published material in to one amazing life guide for you. He lays out themes for each month of the year: Power, seduction, persuasion, strategy, human nature, toxic people, self-control, mastery, psychology, leadership, adversity and creativity. Within these themes he features a “daily law” for you to follow. “By not looking at ourselves in an honest way, and glossing over our own flaws and weaknesses, we become trapped in patterns of behavior that we cannot control,” Robert says in his new book. “As the years go by, and the misreadings, missteps, and unrealistic decisions pile up, we can become bitter confused, and damaged.” “The Daily Laws” is designed to reverse [these] toxic patterns and reconnect you to reality,” Robert says. “It takes aim at the various delusions we have all absorbed and seeks to attune your mind instead to the most entrenched traits of human nature and how our brains actually operate.” Listen on for the truth bombs. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 31, 2023

Let’s explore the mind-bending subject of quantum biology with Dr. Catherine Clinton, a licensed naturopathic physician with a focus on gut health, autoimmunity and psychoneuroimmunology. A respected author, speaker, health advocate, Dr. Clinton has been on the front lines of health and wellness for over 15 years, helping people overcome the very health challenges I once grappled with in my younger years – issues like autoimmune conditions and Lyme disease, which we now understand are often intertwined with mold toxicity. What makes Dr. Clinton’s journey so intriguing is that she not only healed herself but has also guided countless patients on their paths to recovery. Today, we dive into a profoundly fascinating and complex topic Dr. Clinton knows a lot about, but which is still relatively misunderstood among the public: quantum biology. At a high level, it's all about understanding how our health is intricately connected to the world around us, the flow of electrons, protons, photons of light, and even the vibrations of sound within our biological systems. Think biohacking under a mega microscope. We explore the scientific meaning of the word “quantum,” theories surrounding the origins of consciousness, the incredible role of fascia in the quantum highway of our bodies, the impact of polyphenols and melanin, the incredible new discoveries around structured water, and a whole lot more. Plus, we delve into the emerging field of sound frequency research and even touch on Dr. Clinton's new Quantum Sound Masterclass. I appreciate Dr. Clinton’s work at the cutting edge of quantum biology, and look forward to how these discoveries push the biohacking movement forward. (00:05:47) Understanding Quantum Biology: Where Biology Meets Consciousness (00:13:21) Exploring the Origins of Consciousness (00:18:55) A New Study Proving We Are Quantum Beings (00:24:39) What’s Happening In the Quantum Highway of Fascia Throughout the Body (00:30:49) The Function of Polyphenols & Melanin (00:38:11) What Structured Water Does in the Body (00:46:05) Dr. Clinton’s Masterclass on Quantum Sound & Water Consciousness (00:55:16) Sound Frequency: The Next Biohacking Frontier Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: drcatherineclinton.com Quantum Sound Masterclass: drcatherineclinton.com/quantum-sound-masterclass Instagram: @dr.catherineclinton YouTube: Dr. Catherine Clinton ND Facebook: @dr.catherineclintonnd The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 26, 2023

Remember the days when we believed in one-size-fits-all diets? Well, thankfully those days are behind us. Today's episode is all about the crucial shift towards personalized nutrition. Our guests, Matt Gallant and Wade Lightheart from BiOptimizers, are no strangers to the show. They're also the authors of The Ultimate Nutrition Bible, a monumental resource that unlocks the secrets of crafting a diet tailored precisely to your genetics, goals, and lifestyle. We delve into the art and science of creating your perfect nutrition plan, exploring the intricate web of genetics, gut health, and lifestyle, and how they all intertwine to shape your dietary needs. Imagine a diet designed exclusively for you, based on your unique genetic makeup and aspirations. It's a paradigm shift for sure; we're here to guide you through it using the latest scientific studies and findings from our personal experiences with biohacking. In this episode, we uncover the importance of aligning your diet with your lifestyle, debate the calories-in vs. calories-out method of losing weight, and share practical insights for how to measure your progress from The Ultimate Nutrition Bible. Plus, we dispel the myth that excessive cardio is the fastest way to lose body fat, and explore the pivotal role of hormones and metabolism for sustainable, safe weight loss. (00:21) Introducing the Ultimate Nutrition Bible: There’s No Evil Foods (10:54) Why Raw Food & Ketogenic Diets Are Not for Everybody (19:30) The Consequences of a Performance Diet & Starvation Survival Mechanisms (33:32) Exploring the Calories-In, Calories-Out Method for Weight Loss (41:05) Understanding Metabolic Adaptation: Why Excessive Cardio Prevents Fat Loss (46:08) How High Quality Sleep Can Aid Weight Loss (51:33) The Simplest Secret for Tracking Your Progress (56:32) Breaking Down Calories vs. Macros in the Ketogenic Diet (01:00:53) Identifying Hormone Issues Based on Weight Distribution (01:05:22) Taking Risks to Achieve Optimal Results Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books The Ultimate Nutrition Bible: ultimatenutritionsystem.com/dave Website: bioptimizers.com Instagram: @bioptimizers YouTube: BiOptimizers Blog: bioptimizers.com/blog Podcast: Awesome Health Podcast The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 24, 2023

About ten years ago, I began working colostrum into my product development efforts – seeing its game changing nutritional value for exactly what it was, well before the mainstream sank its teeth into it. Today’s guest has the experience and intellect to take us deep into the science behind it. Dr. Sarah Rahal, MD – the brainchild of ARMRA – is a double board-certified pediatric neurologist with expertise in environmental and functional medicine. After years of clinical work and research, she was alarmed by the rise of chronic diseases in young patients due to modern environmental factors like pollutants, pesticides, and more. This led her to leave traditional medicine and develop ARMRA's technology with a mission to minimize the modern environmental impact on human health – a truly honorable and trailblazing path that she explains for us today, from early personal health issues to the future of her fascinating company. More than anything though, this episode serves as the ultimate Colostrum 101 course for anyone interested in learning more, living healthier, and even for those still harboring doubts over things like fasting and ethical sourcing. Dr. Sarah Rahal answers it all and more. (02:59) Dr. Rahal on the State of Children’s Health (05:50) Disillusionment & Leaving the Healthcare System (08:14) Intro to the Formula Industry & Colostrum (12:44) Dr. Rahal’s Near-Death Experience (17:35) Massive Issues in the Dairy Industry (21:27) ARMRA’s Unique Formulation (28:25) Dave Asprey vs. The World (31:33) Collagen or Colostrum? (38:33) Ethical Sourcing of ARMRA Colostrum (42:27) Diet Combinations for Colostrum (44:24) How Colostrum Supports a Healthy Microbiome (54:34) Considering Colostrum as a Food Product Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Visit tryARMRA.com/Dave for 15% off your first order Instagram: @tryarmra The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 20, 2023

Friends, it is my great pleasure to introduce Vani Hari, aka Food Babe, someone I've had the privilege of knowing for nearly a decade. She is a relentless advocate for clean, safe, and wholesome food. She has dedicated herself to a tireless campaign aimed at eliminating harmful ingredients from our food supply, particularly in the United States, where food standards can sometimes be shockingly low. Her efforts have been resolute in challenging major food corporations when their practices are detrimental to the well-being of our children and society as a whole. Vani Hari's mission is driven by a genuine concern for the greater good, and I dare say that she has had a more significant impact on food safety and quality than some of the regulatory agencies tasked with these responsibilities in the first place. Vani’s new book, Food Baby Family: More Than 100 Recipes and Foolproof Strategies to Help Your Kids Fall in Love with Real Food serves as a comprehensive guide for how her family navigates the challenges of living in a world filled with overly processed, unhealthy food options. In this conversation we discuss the importance of educating your kids on processed foods and proper nutrition early on. Vani and I share some of the lessons we’ve learned in teaching our kids about nutrition, and how we’ve empowered them to choose foods that make them feel good. Together, we have the power to stand up against the multibillion-dollar conglomerates that persist in feeding us products that are, in essence, poison. By making informed, healthier choices for ourselves and our families, we can redirect our resources toward companies that are genuinely committed to improving the landscape and producing high-quality products. (00:03:10) Vani Hari's Journey in Food Activism & Resilience How Vani unveiled hidden chemicals in our food Exposing a harmful chemical in Subway bread Read: Feeding You Lies By Vani Hari Being targeted by organized opposition How Vani’s health journey inspired her to find purpose Navigating constant badgering online being paid for by big chemical companies How Gabby Bernstein helped Vani persevere through manipulations and attacks The history of PR in the US What drives Vani to continue this work Read: Food Babe Family By Vani Hari (00:24:16) The Truth About Processed Foods & How to Uphold Your Food Values Socially How the food industry thrives on making food that isn’t good for our health Removing processed foods from your diet The importance of educating kids about processed foods early on Teaching kids to be kind and accepting Communicating why you do/don’t buy certain foods to your kids What happened when I took my daughters to McDonald’s for the first time How fast food hijacks your brain Exposing chemicals in the infamous Pumpkin Spice Latte How to uphold your food values in social settings Why goldfish are banned in Vani’s house and alternative snacks (00:40:41) Helping Kids Navigate Their Food Choices to Make Healthier Decisions Healthy, satiating breakfast ideas for kids Truvani collagen: shop.truvani.com/pages/collagen-peptides Why Kellogg is one of the most evil companies in the world Empowering kids to choose how they feel through the food they eat How processed foods led to Vani’s appendicitis Being a happier parent by being less of a perfectionist How kids can hold you accountable Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Read: Food Babe Family By Vani Hari Website: foodbabe.com YouTube: youtube.com/thefoodbabe Instagram: @thefoodbabe Shop: truvani.com The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 18, 2023

In this episode, we're broadcasting live from Toronto with Dr. Adeel Khan, a leading figure in the field of gene and cell therapies. Dr. Adeel Khan, who holds an M.D. and is a Canadian Board Certified Physician, specializes in regenerative and cellular medicine. He is also a recognized authority as a key opinion leader for The American College of Regenerative Medicine, the foremost advocate for best practices in North America. Notably, he co-founded Xalt, a fitness-technology company, and played a pivotal role in the development of their proprietary technologies. Additionally, he serves as the Chief Scientific Officer for Science & Humans, a virtual hormonal health company. Dr. Khan's expertise extends globally, as he has treated world champion athletes, members of Royal Families, and celebrities in both Dubai and North America. Personally, I'm thrilled to share that I've recently undergone gene therapy for the very first time in my life. This is a significant moment for me because I've been envisioning the potential of this technology in the context of longevity for the past two decades. In fact, I documented my beliefs about the ability to manipulate stem cells to reverse their aging process in my book, Superhuman. The gene therapy I received, which we'll delve into shortly, was administered via a simple injection. Over the next three to six months, it's expected to reduce my biological age, or intrinsic age, by an impressive seven to nine years—a monumental outcome from just one treatment. Throughout this episode, we'll explore various aspects of stem cell research, particularly the historical use of umbilical cells, which may hold some surprising revelations for you. We'll also discuss the challenges in translating cutting-edge medical research into practical clinical applications and the incredible potential of gene and cell therapy in addressing chronic pain, cancer, and other medical conditions. What's particularly exciting is Dr. Khan's multifaceted approach to biology, working on multiple fronts to harness its potential. This innovative approach offers a glimpse into a promising future, and I couldn't be more thrilled to dive into this conversation. (01:36) Exploring the Impact of Technological Advances & Gene Therapy in Regenerative Medicine • Pure Muscle: puremuscleandfitness.com • Unite Mind & Body to Achieve Health & Healing – Dr. Andrew Weil – #656 • How technological advances have impacted the world of regenerative medicine • Learn more: daveasprey.com/genetherapy • Keeping up with the rapid development of medical science • What is plasmid gene therapy? • The history of gene therapy research and accepting the risk of innovation • The attitude towards innovation in other parts of the world • We Can Slow Down Aging Right Now – David Sinclair, Ph.D. – #626 • How phellostatin relates to aging (20:42) Revolutionary & Innovative Approaches to Health & Longevity • Democratizing health for everyone with gene therapy • Benefits of intranasal insulin • How industry cross-pollination encourages lateral thinking • Read: Ego Is The Enemy by Ryan Holiday • Explaining the limitations of umbilical cord stem cells and how they’re being optimized • Using gene editing technology to create specific stem cell lines • Using stem cell technology for hair and the reproductive system • The ability for breast enlargement with stem cells (42:47) Stem Cell & Gene Therapy Applications for Cancer & Chronic Pain • The opportunity for chronic disease healing with stem cell therapy • Using CAR T for cancer treatment • Target gene therapies to fix irregular pathways • Ways to improve mitochondrial efficiency • How bad actors could misuse this technology • The correlation between Tesla’s story and gene cell therapy • Big Pharma and government’s role in the suppression of revolutionary medical technology • Using this technology to build resilience in the body to combat modern stressors (01:10:08) Making Revolutionary Medical Advances More Accessible • The logistics of receiving gene cell therapy: how long they last and how they’re given • Improving the immune system through a microbiome upgrade with FMT • The difference between probiotics and FMT • Stem cell and gene therapy treatments for cardiovascular disease • The regulatory fight for your right to have control of your own biology • The problem with institutionalized medical doctors • Treating chronic pain and recognizing the chronic pain burden Resources Gene Therapy: daveasprey.com/genetherapy Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: eterna.health Instagram: @dr.akhan YouTube: Doctor Adeel The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 17, 2023

Today, we cover something that everybody wants at some level or another—muscle. If you want to live a long time and you've fallen for the plant based nonsense science that's out there to sell more Froot Loops, well, you're heading in the wrong direction from a longevity perspective. The cold, hard truth is that skeletal muscle mass drives longevity. Dr. Gabrielle Lyon joins the show today to flex her own intellectual muscles on protein intake, reframing the hallmarks of aging, supplementing aminos, healthy fascia, and a whole lot more. You've heard her talk about these things online probably as much as I have; she calls what she does Muscle Centric Medicine—and as you can imagine, I am fully on board. She's looking at aging in exciting new ways in her new book, Forever Strong, which is packed with science-based strategies for aging well. We respectfully lock horns on a few subjects near and dear to our hearts—ranging into symptomatology vs. muscle health, key flaws in modern skeletal muscle research, where to draw the line on veganism, unlocking longevity through diet, and more—before landing on our shared responsibility to the greater community to share these insights for the common good. Dr. Gabrielle Lyon is a true heavyweight in the space and my dear friend, backing up her immense aptitude with real life results as a biohacker seemingly aging at a slower pace than one might expect. It’s a pleasure to welcome her to the show today. (02:38) Correlation Between Aging & Skeletal Muscle Mass • Read: Forever Strong by Dr. Gabrielle Lyon • Dr. Gabrielle’s informed background in geriatric medicine • Modern symptomatology vs. skeletal muscle health • Reframing the hallmarks of aging • 40 Years of Zen • Gaps in modern skeletal muscle measuring • A New Whole-Body MRI Scan Sees Everything - Raj Attariwala M.D., Ph.D. #989 • Optimizing genetic potential • Benefits to weight training as a young person • How much weight training is ideal? • Read: The One-Minute Workout by Martin Gibala • Skeletal muscle as body armor (23:30) To Protein or Not to Protein? There’s No Question • Protein intake with regard to longevity • Mythbusting mechanistic target of rapamycin (mTOR) • Kevin Hart ends up in wheelchair after being ‘dumbest man alive’ • One possible benefit to animal protein restriction • Considering protein instead as its 20 amino acids • Benefits to collagen supplementation • Read: The Switch by Mr. James W. Clement • Not-So-Science Fiction: Extending Your Healthspan Gets Real - James Clement #608 (37:29) Applying the Science: Everyday Tips & Practices • Spacing amino acids throughout the day • Dr. Lyon’s longevity protocol • Eating earlier for circadian alignment • Evidence hedging intermittent fasting • Negative impact of alcohol on aging (47:42) Fascia, Muscle & Hernias: What’s the Connection? • Importance of fascia in aging • Recommendations to avoid hernia surgery • Explaining the tensegrity principle as it relates to muscle health • Value of functional movement practice • Link between the virus and an increase in mast cells (50:26) Best Proteins & Why You Shouldn’t Go Vegan • Dr. Lyon’s recommended animal protein powders • Why vegan farts are the real problem • Other important bioavailable nutrients in animal protein • Veganism in younger/older people • Wielding the responsibility to educate • Dave’s health journey and inspiration • Supplementing amino acids • Read: Forever Strong by Dr. Gabrielle Lyon Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: drgabriellelyon.com Read: Forever Strong by Dr. Gabrielle Lyon Instagram: @drgabriellelyon Podcast: The Dr. Gabrielle Lyon Show YouTube: Dr. Gabrielle Lyon Facebook: Doctor Gabrielle Lyon X: @drgabriellelyon The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 12, 2023

In this episode of The Human Upgrade - anesthetist and researcher, Mark Harper, M.D., Ph.D., shares how the power of cold-water practices can treat depression, anxiety, PTSD, arthritis, migraines and other health conditions you may be experiencing. Despite all the attention cold water swimming and immersion has gotten in recent years—thank you, Wim Hof—the scientific community hasn’t taken it very seriously. That’s changing now. Dr. Harper’s research goes beyond what we already know about the benefits of cold-water therapy and lays out best practices for you. In this episode you’ll learn: How to safely establish your own customized practice of cold-water swimming The ideal plunge frequency How to heat your body from the inside out Why using saunas can optimize your plunges The effects of putting your face in cold water vs. just your body Why swimming “in the wild”—lakes, rivers, seas — benefits you even more How community plays a role in cold plunge practices And more You’ll also learn about science and case studies found in Dr. Harper’s book, “ Chill: The Cold Water Swim Cure - A Transformative Guide to Renew Your Body and Mind .” He explains how cold water has the ability to impacts us physiologically and mentally. As Dr. Harper shares his long-awaited evidence on cold-water’s therapeutic power to strengthen the immune system, cell regeneration, and everyday vitality, you’ll come to understand how to harness the power of cold-water swimming. If you are looking to up your cold-water therapy game, you’ll get a lot of value from this episode. Dr. Harper says you can start simply, one small movement into cold water at a time: “Your rest, digest, chill out, and anti-inflammatory response comes from putting your face into the water,” he says. He then goes on to other cold-water swim tips. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 10, 2023

Every 13 minutes, a woman dies of breast cancer. And this unnecessary epidemic affects men, too. Today, you’ll hear a fascinating interview with a woman on a mission to empower people to do more than just survive breast cancer, but become radiantly healthy; Dr. Toni Galardi. She's not only a holistic psychotherapist with a PhD in psychology, but a remarkable individual who cured herself of breast cancer. Dr. Galardi is a prolific author with three books under her belt, including her latest one titled BreastQuake: 10 Steps to Awakening from Breast Cancer. In this episode, we delve deep into the esoteric realm of breast cancer; discussing alternative methods for treatment, lowering the risk of breast cancer, and exploring groundbreaking studies that shed light on the incredible healing potential of consciousness within the body. You see, it's essential to understand that psychology plays a crucial role in the context of cancer. While psychology doesn't cause cancer, ignoring the mind-body connection in the conversation is a missed opportunity. Our bodies possess a remarkable intelligence, residing within our mitochondria, and a distributed consciousness that affects our well-being. So, even if you don't have breasts or breast cancer isn't on your radar, this conversation offers profound insights into psychology's impact on health and wellness. Dr. Toni Galardi is deeply passionate about helping women navigate their cancer treatment plans, emphasizing the importance of aligning with one's passions, as she believes that passion holds significant healing potential. Throughout this episode, you'll learn about Dr. Galardi’s personal journey with breast cancer, the eye-opening studies she uncovered regarding the high cost of treatment, her recommendations for more affordable (and even free) healing tools, and her unique approach to harmonizing the energetic and emotional aspects of the human experience to combat cancer and reduce your risk. I want to extend my sincere appreciation to Dr. Toni Galardi for her courage in authoring this groundbreaking book and fearlessly addressing topics that some may question. She calls it as she sees it, and that's precisely why her insights are so valuable. (02:27) The Role of Shame & Love in the Cancer Recovery Journey • Read: Cancerpreneur by Mike Koenigs • What Toni decided to do when she got her breast cancer diagnosis • The data around how women really feel about their breasts • Who does and doesn’t have shame around their breasts • How Toni’s shamanic training and somatic experience came into her healing process • The World is Your Petri Dish with Bruce Lipton – #336 • The compelling link between shame and breast cancer • Working with consciousness in the body to cure diagnoses • Developing the muscle of dream recall • Intuition is Not a Feeling – Joy Martina – #574 • Loving your breasts into cancer remission (19:26) Optimizing Diet, Lifestyle & Emotional Well-being for Breast Cancer Resilience • Diet changes to implement when diagnosed with breast cancer • How to alkaline your diet & limit acidic foods • Should you avoid dairy or soy if you have breast cancer? • Exploring what the cancer personality looks like • Studies of the impact of negative life events on cancer diagnoses • Energetic cleansing and hygiene tips (35:20) Empowering Self-Care & Healing Tools for Breast Cancer Prevention & Recovery • Diagnostic test recommendations to see if you’re at risk • Queen of Thrones castor oil packs • Using thermography • Read: The Power of Eight by Lynn McTaggart • The high cost of breast cancer treatment compared to other cancers • Using the free tool of the power of eight to heal breast cancer • How toxic relationships & childhood trauma play a role in breast cancer • Watch: A Call to Courage with Brene Brown on Netflix • How to deal with trolls on social media Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: drtonigalardi.com Instagram: @drtonigalardi LinkedIn: linkedin.com/in/dr-toni-galardi-909a5a7 Facebook: facebook.com/drtoni The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 5, 2023

In today's episode I’m reuniting with someone who has had a profound impact on my journey as a biohacker, Rollin McCraty, the director of research at the HeartMath Institute. Rollin specializes in the physiology of emotion, and his research explores how emotions impact cognition, behavior, health, and global interconnectivity. I first encountered Rollin nearly two decades ago during my tenure at the Silicon Valley Health Institute. Back then, I was a young enthusiast, navigating the intricate world of anti-aging and longevity, learning from the seasoned wisdom of octogenarians who were defying the natural aging process. Rollin introduced me to the profound connection between cutting-edge science and practices often dismissed back then, like meditation. In a world where admitting to meditating could raise eyebrows and questions about your sanity, Rollin illuminated the scientific links connecting our biology, nervous system, and conscious mind. It was a revelation, a glimpse into the integral role these connections play not just in personal well-being but in the unseen, yet palpable, impact we have on others. Now, as a 50-year-old with the biological markers that defy my calendar age, I attribute part of my own transformation to insights gained from pioneers like Rollin. As a biohacker, personal development isn’t just a journey inward but a meticulous tuning of the body’s ‘hardware’ to optimize function and performance. In this episode we’re uncovering the impact our energetics can have on others and the world around us. We talk about heart rate variability and coherence, and its importance in aging. We discuss the magnetic environment we live in, and the human response to these natural phenomena. We talk about the impact of phones on our biology, how technology can potentially be harnessed to positively affect human consciousness and global coherence, and changing DNA with intention. And if you’re now motivated to dive into coherence training, we give some tools for that. It’s an honor to have Rollin on the show today, a testament to the evolution of biohacking, where the convergence of science and consciousness isn’t just acknowledged but celebrated. (03:39) Unlocking the Power of Heart Rate Variability & Earth’s Natural Rhythms • What heart rate variability is why it’s important for understanding aging • My experience as a HeartMath coach and using a heart rate variability monitor • How we affect each other from our heart rate coherence • Research conducted through the Global Coherence Initiative on fields line resonances • Why it’s beneficial to be in sync with the rhythm of the earth • An overview of the Schumann Resonances (33:37) How the Earth’s Magnetic Environment Impacts Our Biology • The global magnetometer measuring system • How understanding the magnetic environment we live in can help us be more resilient • What disturbed fields can do to humans • How our phones impact our biology • Measuring global consciousness with Global Consciousness Project 2.0 • Recognizing and pushing past our own limiting beliefs (46:35) Exploring Coherence Training & Quantum Consciousness for Healing • Using technology to affect consciousness in a positive way • Global Coherence app • How we are becoming aware of what we're feeding the field • Where to start with becoming more aligned and shifting into coherence • The role of mitochondria in coherence training • How you can change your DNA with coherence and intention • Biohacking’s link to epigenetics • The World is Your Petri Dish with Bruce Lipton – #336 • Tap into Tapping: The EFT Episode – Dawson Church # 474 • Mastering Brain Waves and Creating Mind Bridges – Dawson Church – #653 • Channeling healing through energetic fields at Joe Dispenza workshops • Biohacking Conference: biohackingconference.com • Rollin’s work with Joe Dispenza • Quantum level processing and consciousness • Global Coherence Initiative: heartmath.org/GCI • Read: Science of the Heart by Rollin McCraty • Read: Heart Intelligence Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: heartmath.org Instagram: @heartmathinstitute Global Coherence Initiative: heartmath.org/GCI The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 3, 2023

In today’s episode, we tackle longevity, exploring workouts optimized for hormones, and dive deep into a crucial quality we all need a bit more of—resilience (or as I like to call it, equanimity). It's about more than just being tough; it's about the ability to maintain your chosen mental and emotional state, no matter what life throws your way. I’m excited to introduce Tony Horton, a name many of you will recognize. We both are passionate about the journey to self-improvement, albeit via different approaches. Tony is a renowned motivational speaker, the author of Bring It, Crush It, and The Big Picture, and the brains behind immensely popular fitness programs, Beachbody Fitness and P90X®. His influence in the world of fitness and wellness is vast, as his insights into healthy living have been shaping lives for years. Today, we uncover the reasons behind Tony's new collaboration with Dr. Mindy Pelz to create a unique fitness program tailored for women's hormone cycle. We also explore the often overlooked roles of humor and mindfulness in promoting longevity and examine how the right workout routine can significantly enhance your relationships. Tony also shares the best ways to move your body to prevent injuries, and imparts lessons from his extensive experience in entrepreneurship. Get ready for a practical, insightful conversation that will hopefully inspire you to move more, laugh more, and continue striving for the best version of yourself at any age. (01:15) Inside Tony’s New Program & Health Recovery Journey • Fast Like A Girl by Mindy Pelz • How Tony collaborated with Mindy Pelz to create a hormone-centric workout plan • The Better Baby Book by Dave Asprey • Being mindful of overtraining • Tony’s experience with Ramsay Hunt syndrome and Bell's Palsy • Full Catastrophe Living by Jon Kabat-Zin • How mindfulness contributes to longevity • Biohack for stopping pox viruses from replicating (21:04) Tony’s Biohacking, Fitness & Longevity Blueprint • Adaptability as a contributor to long-term happiness and resilience • Tony’s tips for establishing a consistent workout practice • Why tracking your progress is core to biohacking • The link between mental health and exercise • How to incorporate cold plunging into your fitness routine • Workout modalities that reduce the likelihood of injury • The value of humor for longevity and happiness (46:44) Diving Into Muscle Confusion, Relationship Harmony & Entrepreneurship • The latest science related to muscle confusion • Early biohacks Tony pioneered • Maintaining testosterone levels as you get older • How the PowerSync60 helps women design workouts around their cycle • PowerSync60: powernationfitness.org/catalog • How exercising in alignment with your hormones improves relationships • The hardest parts of entrepreneurship • Navigating PowerSync60 for women menopausal, perimenopausal, or postmenopausal Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: tonyhortonlife.com Facebook: Tony S. Horton X: @Tony_Horton Instagram: @tonyshorton YouTube: Tony Horton Life PowerSync60: powernationfitness.org/catalog The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 28, 2023

Who doesn’t want more radiant skin? Not only is our skin our largest organ, but it influences our confidence and how we connect with others. That’s why I'm excited to be sitting down at my Austin, Texas studio with skin expert and longtime friend, Rachel Varga. Rachel is a double board-certified aesthetic nurse specialist, having performed over 20,000 procedures since 2011. She was one of the first to combine functional slow-aging techniques, biohacking, and modern medical aesthetics—teaching us how to tune in to what our skin is telling us about our internal health and what to do about it. Not only has she had a significant impact on the world of skin science, but she's also trained countless doctors, nurses, and their teams on the art of aesthetics. I can personally vouch for Rachel's expertise as she's worked on my skin, enhancing it with innovative techniques involving lights and other intriguing procedures. But today, it's not just about aesthetics or vanity. We dive deep into the health of our skin, specifically discussing how to reduce oxidative stress and implement purification and detoxification techniques to become radiant from the inside out. With Rachel's unique insights you don't typically hear in the skincare space, you'll learn secrets to having not just younger-looking skin, but more pure energetics. What you’ll find is that healthy skin is not just about putting some crap on top of it, it's about nourishing your skin from the inside, doing the energetic practices of biohacking, and then using vetted products that actually work and are safe. If you're hungry for more, Rachel helps inspire others with her unique strategies to slow cellular aging and enhance radiance at TheSchoolofRadiance.com and has previously graced us with her wisdom on of this podcast (#668). I also highly recommend checking out her recent paper on Oxidative Stress Status and Its Relationship to Skin Aging. And, be on the lookout for her upcoming book, Radiance: The New Skin Science. (02:11) Combatting Modern Stressors: From Oxidative Stress Status to EMFs • The harm oxidative stress from the environment can cause on your skin • How often you should be washing your face • Benefits of EMF-blocking clothing • EMFs in modern vehicles • How EMFs affect the skin and ways to combat it • How your skin impacts your confidence and ability to connect with others • Acknowledging the impact of lookism • Signs of oxidative stress status (22:02) Conscious Skincare: Navigating Toxins, Purification Processes & Eye Health • Find clean skincare vetted by Rachel: theschoolofradiance.com • Hidden toxins to look out for in “clean” skincare products • the importance of being a conscious consumer of products that touch your skin • The role of purification in keeping skin clean and protected • How to biohack your home to support your skin health • Purifying your home environment to reduce oxidative stress • What’s causing ocular diseases and aging of the eyes • How to protect your eyes as you sleep (37:53) Unlocking Radiance: Biohacking, Detoxing & The Secrets to Energetic Beauty • Detoxing as a part of radiance • Biohacking Conference: biohackingconference.com • The difference between men and women when it comes to radiance and detoxing • The best type of candles to use in your home • Discerning who has truly radiant energy • Understanding the four brains • What happens to your skin when dealing with negative energy (narcissism, stress, toxins) • Benefits of biohacking on your physical and mental state Resources: Use code DAVE and save 15% sitewide at https://TheSchoolofRadiance.com - FREE Biohacking For Ageless Beauty Training! https://www.theschoolofradiance.com/freebies - Book a One on One with Rachel Varga for customized skin care, rejuvenation guidance and ongoing support! https://www.theschoolofradiance.com/consultation - Join SkinCamp for expert Tutorials on skin care, make up, hair care (and growth), biohacking, and more! https://www.theschoolofradiance.com/ - Join The School of Radiance Membership for cultivating resilient radiance through practices and mentorship: https://www.theschoolofradiance.com/membership Subscribe to The School of Radiance Podcast: https://www.theschoolofradiance.com/podcasts Follow @rachelvargaofficial on all platforms (except twitter) Podcast: Face Aging with the Science of Beauty – Rachel Varga #668 EMF Resources: daveasprey.com/tag/emf Study: Oxidative Stress Status and Its Relationship to Skin Aging Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 26, 2023

In today's episode, we're joined by Dr. Gad Saad, a professor of marketing at Concordia University's John Molson School of Business. More significantly, Dr. Saad has spent a decade as the research chair in evolutionary behavioral sciences and Darwinian consumption. Beyond his extensive research and academic accolades, Dr. Saad reaches out to a broader audience, sharing his insights through his popular blog, YouTube channel, and podcast. As someone deeply interested in challenging harmful ideologies, I've taken note of his impactful book, The Parasitic Mind. Today, I'm particularly eager to delve into the findings of his latest release, The Saad Truth About Happiness. In our discussion centered around his newest book, we delve into the evolutionary aspects of happiness. As someone who's written extensively on longevity and aims to live to at least 180, I believe in the importance of happiness as a skill. With Dr. Saad, we explore living the life you truly desire, the role of anti-fragility in happiness, and the inherent biological differences in male and female behaviors. It's crucial, especially in today's climate, to understand the triggers that may be rooted in our biology or false belief systems. Drawing from personal experiences, I can vouch for the invaluable insights in Dr. Saad's book. Listeners, it's a must-read for those keen on understanding and cultivating happiness. (03:50) Decision-Making in Relationships & Academia • Must-have ingredients for happiness • The impact of your relationship on happiness • When do you make the decision to decouple from a relationship? • How statistical decision theory applies to academia • Read: The Parasitic Mind by Dr. Gad Saad • The garage band effect that occurs in academia that prevents action-taking • Why academics who go on the Joe Rogan Experience are ridiculed by peers • Read: The Laws of Human Nature by Robert Greene • Behind the scenes of our interviews on Joe Rogan’s podcast • Joe Rogan Experience #275 - Dave Asprey • Joe Rogan Experience # 2012 - Dr. Gad Saad • Happiness in moderation vs. living high on life (19:40) Perfectionism, Criticism & The Genetics of Happiness • Navigating the inverted U curve for perfectionism • Handling the two groups of critics • The Science Behind Just One Mold Toxin in your Coffee by Dave Asprey • The genetics of happiness • Applying the psychometric scale of internal vs. external locus of control to happiness • How our evolutionary behaviors can become maladaptive in modern society • Exploring how having children impacts happiness • What the research shows about how to choose a long term partner (47:10) Evolutionary Insights on Mating, Cheating & Play • The evolutionary roots of sexual variety seeking • Why certain cultures tolerate women on the side more than other cultures • The impact of birth control and hormonal changes on fertility and attraction • Read: The Mating Mind by Geoffrey Miller • The link between the ovulatory cycle and women's beautification • What increases men’s testosterone: a study providing context for the mid-life crisis • Why play is essential for happiness • The re-education of Jordan Peterson • Read: The Saad Truth About Happiness by Dr. Gad Saad Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: gadsaad.com Read: The Parasitic Mind by Dr. Gad Saad Read: The Saad Truth About Happiness by Dr. Gad Saad X: @ GadSaad Podcast: The Saad Truth YouTube: youtube.com/channel/UCLH7qUqM0PLieCVaHA7RegA Instagram: @ doctorgadsaad Facebook: acebook.com/Dr.Gad.Saad Linkedin: linkedin.com/in/gad-saad The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 21, 2023

Today, we welcome back a guest from the early days of this podcast, fellow former vegan and esteemed researcher and scientist, Chris Masterjohn. Chris Masterjohn earned his PhD in Nutritional Sciences from the University of Connecticut, and has worked as a postdoctoral research associate and Assistant Professor of Health and Nutrition Sciences. In 2016, he transitioned to entrepreneurship. These days, Chris conducts independent research, consults, develops information products, and creates free content to help people improve their health. Chris is dedicated to sharing practical principles from complex science, and to the pursuit of truth and continuous learning. He's a biohacker from before the word “biohacking” came to be, appearing on episode 16 of this podcast when I was just getting that movement started, because he not only pays attention to how stuff works in the world and academic research, but he hacks his own body. I've always liked the way he thinks mechanistically about biology, nutrients, and what to eat. In this conversation, we talk about how to recover from veganism and reverse the effects of oxalates, highlighting the long term health impacts of the vegan diet. His own self experimentation lately is of particular interest to me as he’s been exploring the intersection of genetics and mitochondrial health to heal niche health conditions and even quell extreme fears or stressors. We also talk about the link between energy metabolism and psychological trauma, chronic pain and oxalate overload, and even explore the potential dangers of methylene blue from his latest 58 page research paper breaking down the importance of correct dosing. If you’re a true biohacker, you’re going to love this deep dive into how minerals and metabolism play a huge role in our biology. (03:47) Genetic Optimization: A New Approach to Healing Chronic Pain & Disease • How his perspective on nutrition has changed since our first episode • The extreme effects veganism had on his health • Using genetics research to find solutions to rare health issues • The role of AI in diagnosing health conditions—now and in the future • Focusing on mitochondria as the root cause to heal health issues • Access his program: chrismasterjohnphd.com • What will reverse the anti fertility trend? • The psychological rewiring required to heal chronic disease states • Lowering your stress response with GABA and hierarchical exposure therapy • How energy metabolism and psychological trauma symptoms are related (32:08) Recovering from Veganism & Oxalate Overload • Can you do veganism well? • Addressing the impact of plant toxins and oxalates • The link between chronic pain and oxalate overload • How to reverse the effects of oxalates • The use of biotin to clear oxalates and dosing suggestions • Read: Toxic Superfoods by Sally Norton • Oxalate dumping symptoms explained • Advice for recovering vegans • Read: Le Chatelier's principle • Viome: viome.com (01:04:09) Methylene Blue: Potential Dangers & Dosage Recommendations • The dangers of combining methylene blue with ayahuasca and psychedelics • Research conclusions on methylene blue dosing • How methylene blue can impact people with Alzheimer’s • Side effects of combining methylene blue with SSRIs • Using methylene blue to help allergy sufferers • ED as a side effect of methylene blue Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: chrismasterjohnphd.com Facebook: facebook.com/chrismasterjohn X: twitter.com/ChrisMasterjohn Rumble: rumble.com/user/chrismasterjohn YouTube: youtube.com/user/chrismasterjohn Gab: gab.com/chrismasterjohn Telegram: t.me/chrismasterjohnphd GETTR: gettr.com/user/chrismasterjohn Podcast: Everything You Need To Know About Saturated Fat & Cholesterol with Chris Masterjohn #16 Podcast: Nicotine, the Perfect Psychotropic? Dr. Paul Newhouse # 494 The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 19, 2023

If you struggle with retaining sharp focus or have been diagnosed with ADHD or other conditions that impede your brain from functioning at its optimal level, this is the podcast episode for you. We learn about a (literally) out-of-the-box solution to attention training—video games. Yes, you read that right. Our guest today, Dr. Adam Gazzaley, holds an M.D. and Ph.D. in Neuroscience from Mount Sinai School of Medicine and completed Neurology residency at the University of Pennsylvania, followed by postdoctoral training in cognitive neuroscience at UC Berkeley. He's currently the David Dolby Distinguished Professor at UC San Francisco and the Founder/Executive Director of Neuroscape, a center focusing on technology-driven scientific research. So it’s safe to say that Adam is not your prototypical basement gamer. As someone who struggled with focus and attention due to Asperger’s syndrome and brain fog due to the effects of toxic mold exposure, figuring out how to retrain my brain to be able to retain more information and focus longer was one of the first areas of biohacking I ever explored. This is why I’m so excited to be talking all about Endeavor Rx today, the world's first FDA-authorized prescription video game treatment for pediatric ADHD—and Endeavor OTC, for adults who struggle with ADHD, focus, attention, and distraction. We explore how we can measure attention and improvement in focus, the biological systems that control what we focus on consciously and subconsciously, the role of nutrition in our ability to focus, the underlying technology of Endeavor, measuring its effectiveness, and Adam’s vision for how we can use biosensing technology—now and in the future—to optimize awareness, focus, mood, and more. (03:07) Addressing Modern Attention Challenges • Defining our attention systems and how to measure them • How I learned how to pay attention, even with ADHD • Read: The Distracted Mind by Adam Gazzaley and Larry D. Rosen • Tools we have for addressing attention challenges • What I use now for brain function and focus • The role nutrition plays in being able to focus • What typical of video games can aid in training attention • The potential negative effects of shooter games (20:37) Understanding Endeavor: How to Train Attention Using a Video Game • Top down vs. bottom up thinking • Endeavor: the video game that trains your attention • The journey of getting Endeavor approved by the FDA • The effectiveness of Endeavor for adults • What to expect from playing Endeavor • How you can utilize multimodal biosensing for quantifying physiology • Hugs from Dr. Love with Paul Zak – #334 • Exploring what technology is used in a sensory immersion lab, including AI (49:21) Exploring Potential Costs & Opportunities of Biosensing Technology • Understanding the potential adverse effects or downsides of this technology • Join the Live Audience: ourupgradecollective.com • The exhaustion factor in playing Endeavor • What video games would be likely to reduce cognitive function • Using Lion’s Mane for increasing brain function • What this system could look like in 10 years Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Endeavor OTC: https://www.endeavorotc.com/ Instagram: https://www.instagram.com/endeavorotc/ Website: https://gazzaley.com/ Instagram: https://www.instagram.com/adamgazz/ The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 14, 2023

I am a sucker for supplements with extensive and impressive research to prove their biohacking benefits, and OMNi-BiOTiC is one of them. Research studies by OMNi-BiOTiC show a 50% or 70% improvement in things like brain function, insulin sensitivity, and detoxification which is really compelling—and exactly why we have Hannah Kleinfield on the show today. Hannah Kleinfeld is the Chief Operating Officer of Allergosan USA, the U.S. joint-venture partner of Institut Allergosan, a global leader in microbiome science and gut health products. She is dedicated to educating about the importance of gut health as a foundation for wellbeing and passionate about helping others experience healthy and vibrant lives. That passion is clear in today’s episode where she shares the research and broad-ranging benefits of the OMNi-BiOTiC line of probiotic supplements. We talk about why it’s so important to have a thriving gut, the important link between gut health and brain function, what is most likely to harm our guts, especially in the US, and how to find which probiotic is right for you. If you're into biohacking, whether you're already doing really well and you're looking for what's next, or you've still got that extra 20 pounds that won't budge but you can see you're moving in the right direction, this might be a really big step to help move you toward your goals. If you’d like to try these products for yourself, go to omnibioticlife.com and use code DAVE20 to get 20% off. (02:24) Revitalizing Gut Health with New Technology • Repairing her gut after Lyme disease • The difference between European and US-based supplement brands • Shop OMNi-BiOTiC (use code DAVE20 to get 20% off) • Where to start with probiotics • What is most harmful to the gut (19:25) Probiotic Power: Detoxing, Brain Boosting & Insulin Resistance • How to address a bad bacteria—Clostridium difficile • How a probiotic can change your brain activity • Delivery method of OMNi-BiOTiC • Exploring the benefits of OMNi-BiOTiC Hetox for liver support and insulin resistance • Recommended tests for monitoring what’s going on in your body (34:41) All You Need to Know About Probiotics • Why OMNi-BiOTiC doesn’t use spores • Pairing OMNi-BiOTiC with other probiotics • What people should know about probiotics • Tips for clearing SIBO • When to take probiotics after being on antibiotics Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: omnibioticlife.com (use code DAVE20 to get 20% off) Instagram: @omnibioticlife The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 12, 2023

Today's episode is with my friend Susan Bratton, who is an intimacy expert with 20 years of experience. She runs a publishing company called Better Lover, and has a supplement company called The 20. Her expertise is in ageless sexuality, sexual biohacking, libido supplementation, and sexual regenerative therapies that roll back the clock on aging. Whether you're a man or a woman, you’ll learn the specific things you can do to change the performance, the shape, the sensitivity, and the longevity of this amazing part of your body. All life on earth—human and otherwise—runs through the same set of automated decision making that happens before your brain even gets engaged, one of which is what we’ll be talking about today, which keeps the species alive forever. Let’s call it fertility. It is actually a source of nourishment for us. So when you're of the appropriate age, this is as important as eating, breathing and drinking water. Yet, we pay more attention to our food than we do to our reproductive and recreational sides of staying connected to our humanness. That's why Susan's on the show today. She shares the science behind the link between intimacy and longevity, explains how to prevent atrophy in these important areas of our bodies, dispels myths about self-pleasure, gives a tutorial on all kinds of toys that can increase function and pleasure for all genders, and lists tips for creating more connection and communication in the bedroom. If you want to check out any of the toys or guides mentioned in this episode, go to moredave.com . (03:14) How to Live Longer by Engaging in More Intimacy • Honoring sexual expression outside of the gender binary • The Human Awareness Institute: www1.hai.org • How to regenerate and enhance your sex life • Interesting insight on semen retention • The correlation between regular intimacy and lifespan • Categories of pleasure toys for men and women • The benefits of vacuum erection devices and how to use them • Sexual enhancement products and guides: moredave.com (26:12) Orgasmic Cross Training: Toys & Supplements to Expand Pleasure Potential • Natural nitric oxide supplements that help reverse atrophy • How Nitric Oxide Controls Oxygen & Nutrient Delivery, Aging & Quality of Life - Nathan Bryan, Ph.D. / Pneuma Nitric Oxide #1041 • Regenerative stack for male and female enhancement • How to fix atrophy and focus on engorgement in female reproductive parts • Orgasmic cross training: 8 different toys for females • How often a man or woman should self-pleasure in order to maintain their potency • The different types of vibrators and their uses (42:02) The Power of Safe & Proper Touch for Female Pleasure • Orgasmic cross training: 4 different toys for males • Understanding the vulval activation and sensory pleasure women need prior to penetration • Why yoni massages can be so powerful • The effects of shame and lack of proper touch in receiving pleasure for women • The bullseye touch technique: betterlover.com • Sex Life Bucket List: moredave.com Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books More Dave: moredave.com Website: susanbratton.com Instagram: @susanbratton Facebook: Susan Bratton X: @susanbratton Linkedin: Susan Bratton Blog: betterlover.com Sex Life Bucket List: moredave.com The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 7, 2023

So much of your reality is determined by your brain, and if you have dealt with chronic disease or mental health struggles like me, it can feel like there’s something wrong with you. But, it’s probably not you. It’s probably a brain problem. Today’s guest, Dr. Brandon Crawford, is here to provide some hope and some answers. Dr. Brandon Crawford is a board-certified Developmental Functional Neurologist, driven by training from esteemed minds in chiropractic, functional neurology, and functional endocrinology. Renowned as a laser expert, Dr. Crawford shares groundbreaking laser and light therapy protocols in lectures around the world, revolutionizing treatments for various conditions through photobiomodulation. He has achieved absolutely incredible results helping people rewire their brains and heal chronic conditions at the NeuroSolution Center of Austin. In this conversation, we dive into the really cool technology and research he uses to do it – and share things you can do at home to improve your own brain health. You’ll learn how to hack your brain with light, get an intro to light hygiene, and be educated on the ways we derive energy from light. We also cover indications of a healthy brain and how to continuously promote brain health, why talk therapy may not be the best way to heal trauma, immediate solutions for when you’re feeling activated by fear, and share advice for parents with kids struggling neurologically after the pandemic mask mandates. (02:36) Optimizing Your Brain With the Right Light • Blue light’s impact on brain tissue • How to combat light toxicity with red light exposure • TrueLight Luminaire: shoptruelight.com • How OCD can be a superpower • Why lasers are used in the NeuroSolution ESM methodology • Read: The Fourth Phase of Water by Gerald Pollack • A discussion on how we derive energy from light • Practices for getting more sunlight without causing skin harm • How you can hack your brain with light • TrueDark glasses: truedark.com • 40 years of Zen: 40yearsofzen.com (27:50) Tools to Measure Neurological Health & Heal the Vagus Nerve • Leveraging beam physics to heal chronic health conditions combining light and frequency • What to expect from a consultation at NeuroSolution Austin: neurosolutionatx.com • How balance indicates neurological health • Is coffee good or bad for the brain? • Danger Coffee: dangercoffee.com • Why cognitive behavioral therapy may not be as useful as laser therapy • The science behind healing trauma through vagus nerve stimulation • The Birth of LSD with Dr. Stanislav Grof, Father of Transpersonal Psychology #428 (44:21) How to Manage Triggers & Support Kids’ Neurological Development • How to stop a panic attack or fear paralysis state using breathwork • How we’ve reinforced ancient practices through science • Vagal nerve hacks for frustration and anger • What stimulating the cymba concha can do for your vagus nerve • How masks have inhibited childrens’ abilities for facial recognition and social engagement • How to restore neurological damage in kids that have occurred over the last 3 years • Things parents can do at home to help kids affected by mask mandates Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books NeuroSolution Austin: neurosolutionatx.com Website: neuro-solution.com Instagram: @neuro_solutions Truedark: Truedark.com The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 5, 2023

If you're frustrated with a system prioritizing profit over societal well-being, this episode is pivotal. Today, we dive deep with Ivor Cummins, a Dublin-based biochemical engineer with a knack for simplifying complex topics. Based on his personal history of insulin resistance and health struggles, he was able to self-heal through nutrition and a low carb diet. In this conversation, we examine the nexus of insulin resistance, heart health, and the current medical system’s failure to diagnose and treat metabolic diseases. Our discussion sheds light on the origins of our current societal framework and its influence on our health and choices. Ivor's unique perspective, combining the understanding of intricate systems in both power and biology, illustrates a clear parallel: We’ve been given systems that aren’t working for the greater good. In many cases, our health is in our own hands. Mine and Ivor’s stories of weight loss are two of millions examples of that. However, recognizing these facts offers hope, because when you’re informed and aware, you have the freedom to choose what’s right for you, and the confidence to stand up for it. With that goal in mind, we examine the impact of influential figures like the Rockefellers and J.P. Morgan, discuss what’s going on at the WHO in response to the recent COVID pandemic, and explain the need for distributed versus central governing systems, among many other blockades to true freedom we’re currently facing. Expanding our collective awareness through these conversations is the key to reclaiming control over our lives. Lastly, I can’t emphasize enough the power of consumer choice. Institutions can't dictate our spending without offering value. There's a peaceful, two-fold solution to our current dilemma— leveraging technology and altering our behaviors. But most importantly, dispelling the pervasive myths that have clouded our understanding and judgment for decades. (03:22) Ivor’s Journey: Healing Insulin Resistance with a Low Carb Diet • The metaphor behind The Fat Emperor • Test results and research that encouraged Ivor to change his eating habits • What Ivor experienced through trying a low carb diet • How to get your appetite and cravings under control with proper nutrition • The science behind insulin vs. cholesterol • What’s missing in medical training to properly diagnose and heal metabolic syndrome? (24:27) America’s Monopolist Legacy: Shaping Health & Political Systems • Addressing the implications of the new WHO treaty’s verbiage and requirements • Explaining the Pandemic Business Model • The history of the Rockefeller Foundation & United Nations trilateral commission • Dr. Jakob Nordingaard's Interview • J.P. Morgan’s influence on society • The cultural impacts of monopolists’ agendas and propaganda (37:44) The CBDC Threat, Power Dynamics & Achieving Cognitive Freedom • Hidden dangers of the Central Bank Digital Currency • The importance of having a distributed power model vs. central model • What we can do to create positive change in a corrupt system • How to achieve cognitive freedom Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Fat Emperor Podcast: thefatemperor.com/podcasts Website: metabolicduo.com YouTube: @IvorCumminsScience X: @FatEmperor The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 31, 2023

You've heard lots on this show about biohacking, longevity, and how to help your brain and body perform better. But what if you could do the same things for your pet? I've spent most of my life with pets and/or farm animals so I’m thrilled to have my longtime friend, Dr. Gary Richter, America's favorite veterinarian, here to tell you all you need to know about biohacking for your pets. Dr. Gary Richter, DVM, is a distinguished veterinarian, international bestselling author of The Ultimate Pet Health Guide, and founder of Ultimate Pet Nutrition. He’s also the author of two new books, Longevity for Dogs and Longevity for Cats. Dr. Richter is certified in veterinary acupuncture, as well as veterinary chiropractic, understanding the benefits of both conventional and holistic treatment methods. He also places great emphasis on the well-being of the pet owner, knowing that a sick pet can cause great strain on a person's life. Today, we talk about what supplements your pet should be consuming, how you can regenerate their health, genetic testing for pets, what's coming in the future, the things a lot of people believe about pet diets that are absolutely not true, and a bunch of other stuff from a top expert in the field. All the studies show that having a pet raises your oxytocin. It makes you live longer. It increases heart rate variability. It makes your kids have healthier gut biomes, on and on. Tune in to start learning how to support your pets as well as they support you. 00:03:00 — How Long Can Our Pets Really Live? • The truth about vegan cat food • How long cats and dogs can live • Why biohacking pets may be easier than for humans • Why dogs like cat poop • The oldest animals he’s worked with • Physiological differences between dogs and humans • How much it costs to invest in your pet’s longevity • Pillars of aging for pets • The root of genomic instability and suggested solutions 00:16:22 — Nutritional Support & Preventative Care for Pets • What to feed your pets for optimal health • Easy and readily available supplements for your pets • Upgrade Labs: ownanupgradelabs.com • Dave’s experience with electroacupuncture for his dachshund • Documentary: daveasprey.com/heal • Testing you can do for your pet to find out predispositions • How much Vitamin D you need in your pet food 00:39:41 — Top Supplements to Support Your Pet’s Optimal Health • Can you and your pet take the same supplements? • What a whole food diet looks like for pets • Benefits of MCT oil for dogs and cats • Read: The Ultimate Pet Health Guide by Dr. Gary Richter • Recommendations for how many supplements your pet needs • Racehorse biohacking • Dr. Richter's supplement list for dog/cat longevity • Read: Longevity for Dogs by Dr. Gary Richter • Read: Longevity for Cats by Dr. Gary Richter • Integrative Veterinary Medicine: ahvma.org • Ultimatepetnutrition.com (Use promo code ULTIMATEHEALTH40 for 40% off) Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Ultimate Pet Nutrition: ultimatepetnutrition.com (Use promo code ULTIMATEHEALTH40 for 40% off) Free Resource: Dr. Richter's supplement list for dog/cat longevity Read: The Ultimate Pet Health Guide by Dr. Gary Richter Read: Longevity for Dogs & Longevity for Cats by Dr. Gary Richter Read: The Ultimate Pet Health Guide by Dr. Gary Richter Integrative Veterinary Medicine: ahvma.org Website: drgaryrichter.com The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 29, 2023

Our guest is Jack Dell’Accio, the CEO of Essentia. Essentia has been working on non toxic, organic mattresses for 20 years. Of most importance to Jack is the impact of restorative sleep in terms of recovery from disease, prevention of disease, longevity, and performance. He's funded a bunch of research on sleep quality and has worked directly with health gurus including myself, professional athletes, various teams in the NBA, NFL, MLS, and over 25% of active NHL players on creating healthy sleep performance. Essentia’s organic mattress has been recognized by several internationally renowned organizations including the Mayo Clinic’s Well Living Lab, and has been named the #1 foam mattress by Consumer Reports for seven consecutive years. If you're a long time listener or you've read some of my books, you understand how getting a lot of sleep is probably not good for you. If it's more than eight hours, your chances of dying are higher than people who get seven hours a night. The reason I wanted to have Jack on the show today is to go over the latest data on how sleeping on an organic Essentia mattress can improve REM and deep sleep by between 20 and 60 percent. Remember—it's not the volume, it's the quality of sleep that matters. Jack provides actionable data on how to improve the quality of your sleep through ensuring your mattress is supporting you from a biological standpoint, so you can make every minute count. We explore what the organic Essentia mattress is made of and the technology that sets it apart from others on the market. We also share our tips for getting the best quality sleep you can get, and how getting regular deep sleep impacts all other areas of your life. 00:02:35 — How Non-Toxic Essentia Mattresses Support Sleep on a Chemical Level • Why athletes aren’t able to sleep well • The number 1 thing impacting your sleep quality • Environmental toxins’ impact on brain metabolism • Why comfort might not be the most important factor in your mattress • Shop: myessentia.com/daveasprey • How Essentia prevents mold in mattresses • Why putting quartz in mattresses is beneficial for blood cell performance • Exploring the science behind quantum effects 00:26:34 — Unraveling Sleep Secrets: Longevity, Light & Legislation • Measuring heart rate variability to determine quality of sleep • How long the people who live the longest sleep • True Dark: truedark.com • The implications of the government’s ban on all incandescent light bulbs • Why there’s legislation around what mattresses are made of • The resistance Jack received from chemists in removing chemicals from mattresses • How a decrease in sleep quality can accelerate the rate of aging • The Bulletproof Diet: daveasprey.com/roadmap 00:44:40 — Biohacking Rule #1: Prioritize Quality Sleep • The importance of rest for recovery and performance • Sleep: sleepwithdave.com • Mattresses for women versus men • Sleep hacks for temperature management • The specs, content and density of the Essentia Mattress • Upgrade Labs: ownanupgradelabs.com • Biohacking Conference: biohackingconference.com • How to determine if a company’s marketing claims are real or fake • Exposing marketing over substance in the mattress industry • Mold Documentary: moldymovie.com • What Jack is developing to improve people’s wellness through sleep Resources: Upgrade your sleep today! Take advantage of Essentia’s Labor Day Sale PLUS use promo code DAVE to get an ADDITIONAL $100 OFF your mattress! Visit MyEssentia.com/DaveAsprey to learn more. Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Instagram: @essentiaorganicmattress YouTube: Essentia Organic Mattress TikTok: @essentiaorganicmattress Jack Dell’Accio: @jackdellaccio The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 24, 2023

The environment you live in has the most profound impact on your health and wellbeing, but are you aware of the toxins and pollutants we’re surrounded by on a daily basis? That is why today’s episode is so important. We talk about toxins that are overlooked in your house and what you can do about them. Our guest is Ryan Blaser, the founder and CEO of Test My Home, an environmental company dedicated to improving your health by changing the environment around you. As a functional medicine doctor for your home, Ryan uses his expertise in building biology and healthy home consulting to identify and address toxic sources that could be impacting your health. After a unique personal wellness journey, Ryan founded Test My Home to help others achieve optimal health. He personally experienced the detrimental effects of mold exposure and lead inhalation, which caused unusual and serious health symptoms like fatigue, weight loss, and brain fog. After unsuccessful attempts with conventional doctors, Ryan took the initiative to investigate his home environment and found the source of his health issues. He cured himself and is now sharing his knowledge and experience with the world. The definition of biohacking is to change the environment around you, and inside of you, so you have full control of your own biology. This is a part of core biohacking, and it's one I think a lot of us just don't think about. We take our supplements, we do our cold plunges, we do all the different biohacks, but just cleaning up the environment around you could make a really big difference. So, in this episode you’ll learn about the most common pollutants and toxins in your home, how to identify them, and ways you can mitigate or eliminate their effects. WE APPRECIATE OUR PARTNERS, CHECK THEM OUT AND GET YOUR DISCOUNT! 5 part healthy home mini course: https://www.happyhome5.com/ Test My Home: https://www.testmyhome.com/ If booking through the website with TMH's sales team, mention Dave Asprey for a discount! Instagram account for lots of free content: https://www.instagram.com/testmyhome/ 00:00:17 — The Top 5 Pollutants Indoors & What To Do About Them Ryan’s personal experience getting sick from environmental toxins Moldy Movie: moldymovie.com The myth behind green buildings Solutions for toxic mold exposure in residential buildings How to identify mold in the home What you should do if you have a smelly home instead of air fresheners How important is a gas stove vs. an electric range? How lighting affects us and types of lights to use in your home 00:21:30 — Understanding the Dangers of Fragrances, Mold & VOCs The surprising ingredients in candles and air fresheners Homebiotic spray: homebiotic.com/product/homebiotic-spray What to do when you live in humid environments to prevent mold Meridian Upgrade Labs: upgradelabs.com/meridian Tips for dealing with moisture in your home Recommendations to mitigate carbon monoxide dangers Explaining VOCs and how you can absorb or filter them out The extreme toxicity and effects of formaldehyde 00:42:11 — Sneaky Pollutants: Protecting Your Home from Gas & Noise Symptoms of a leaky sewer gas Ozone pollution versus ozone therapy Sneaky places you can find surface radiation from nuclear plants Protecting yourself from small particles Reducing noise stressors in the home Learning to listen to your body and intuition to identify toxins or stressors Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Moldy Movie: https://moldymovie.com/ The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 22, 2023

Alan Graves is the CEO of Do Not Age, a UK-based longevity company, and he’s been fully immersed in the biohacking space since 2019. In that short time, he’s become a leader in supplementation and expanded his curiosities—even as far as outer space. We talk about his preparation for an upcoming Virgin Atlantic flight to the stars, and how he plans to protect his human form in such an environment. We also touch on our dieting journeys—from veganism to all-meat and everything in between, ride the pharmaceutical industry for its ongoing role in promoting sickness in many forms, and sing the praises of Do Not Age’s innovative line of products. From deep space to raspberries, detailed biochemistry to FDA politicization, this episode has it all—as Alan wields an informed and inquisitive perspective on all things biohacking, past, present, and future. 00:01:52 — Going to Space: Preparation, Inspiration & Motivation • Alan’s preparation to go to space with Virgin Atlantic • Looking ahead to a total perspective change • Dave’s family background in aerotech • Sending a coffee bean to the moon (maybe) • Exclusive: Interview with Ketone Expert Dr. Richard Veech #299 00:08:14 — Avoiding & Counteracting Antinutrients • Remembering their vegan experiences • Dave’s current diet and how he got there • The Bulletproof Diet by Dave Asprey • Liam Hemsworth and oxalic acid • Why you shouldn't eat raspberries • Beef vs. chicken vs. fish 00:14:55 — Becoming a Biohacker: How, When & Why? • Realizing longevity can be extended • Translating scientific papers for the layman • Who paid for the paper? • We Can Slow Down Aging Right Now – David Sinclair, Ph.D. #626 • Investing with integrity 00:22:49 — Do Not Age (DNA) Products & Innovation • Long term view on research at Do Not Age • Taking the hacker approach to business challenges • Update on NMN’s status in the US • Importance of guaranteed purity • Breaking down Do Not Age ’s resveratrol offering • The role of sirtuins in our body • Resveratrol vs. pterostilbene • Singing the praises of Calcium AKG • Prevention is easier than treatment 00:42:33 — What’s Next? Looking Ahead at Longevity • How long do you think you’ll live? • Artificial intelligence is based on the past, not the future • The rise of collagen peptides • Low cost + high efficacy + data proven • Dosing daily collagen tips • Dave takes a visit to Walmart headquarters • Testing for false product claims on Amazon • How and why to buy the good stuff Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Do Not Age: donotage.org Instagram: @do.not.age Facebook: @DoNotAge.org X: @Do_Not_Age The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 17, 2023

Dialing in from Dubai, today, we hear from global inventor and investor, Saba Yussouf, about how to position STEM technologies – science, technology, engineering, and math – to prevent infection, treat water, and even fight 100-year problems like climate change. Half business leader and half scientist, herself, she is a futurist, versed in the fine-tuned details of STEM, and putting it all to work through her disruptive investment record around the world. We learn about nanobubbles and their benefit to the brain, unpack the power of intuition and where it comes from, meet the monstrous homunculus, and so much more. We also highlight Saba’s most recent projects, Invisi Smart and Ficks Labs, tip our caps to groundbreaking research of the past, and look to a brighter (and smarter) future in this forward-thinking conversation. If you need to feel good about where the world is headed, and who might lead us there, this is the episode for you. 00:02:06 — Biohacking the Brain: What are Nanobubbles? • TrueDark anti jet lag glasses • Learning about nanobubbles • Efficient oxygen delivery to the bloodstream • This is your brain on oxygen • Research: Healthy fats and exclusion-zone size • What else can be delivered through nanobubbles? 00:09:52 — Letting Intuition Be Your Guide • The marketing vs. engineering innovation death loop • How did Saba Yussouf learn intuition? (Hint: She didn’t) • Why women tend to know the truth • How do you avoid overthinking your intuition? • Galvanic skin response and muscle testing • The brain cells in our stomach • Meeting the homunculus • Science is in your heart, not your brain • What it means to be a scientist 00:24:05 — Realizing the Consciousness of Water • The groundbreaking work of Dr. Masaru Emoto • Why Saba doesn't drink water when processing negative thoughts • Speaking, or singing, positive affirmations to your water • How ice crystals have been shown to react to music 00:29:09 — Understanding the Innovation Behind Invisi Smart • An update on titania disinfectant technology • All natural and mineral-based formula • When the world says “no thanks” to disruptor tech • Invisi Smart and pivoting to cleaning up greenhouse gasses • Saving the world one stinky armpit at a time • What is Ficks Labs? • Disruptive deep science meets affordable luxury • The disinformation in modern advertising Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Invisi Smart: invisismart.com Instagram: @sabayussouf The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 15, 2023

IN THIS EPISODE OF THE HUMAN UPGRADE™, we revisit a conversation Dave had with Magnus Lygdbäck in Spring of 2022. You’ll learn how a trainer of superheroes and superstars combines core principles of fitness, nutrition, structure and balance. Magnus Lygdbäck, a Swedish health and wellness expert, entrepreneur, and lifestyle coach, joins the show to discuss powering your life in ways that most benefit your health and energy. For more than 20 years, he’s trained some of the world’s most recognizable actors, musicians, athletes, artists, and high-performance business entrepreneurs. Musicians like pop stars Katy Perry, Dua Lipa, Harry Styles and Britney Spears. Actors like Gal Gadot for Wonder Woman 1984 ; Alicia Vikander, for Tomb Raider ; Ben Affleck, for Justice League; and many more. He designed Alexander Skarsgård’s incredible transformation for the lead role as a Viking Berserker in the brand new movie, The Northman . Even with his “celebrity trainer” title (which he doesn’t love), Magnus is quick to say, “It's not who you train, it's how you train.” His Magnus Method training philosophy embraces the “ethos of an athlete.” This all-inclusive approach to performance includes an athlete’s intensity and structure, while also maintaining balance and energy. Time-zone travel, long days of filming, rehearsals, and the constant demands on a celebrity performer’s time means examining all aspects of fueling, rest and recovery. The same applies to the everyday lives of mere mortals. He encourages being open to learning new things and seeking out discomfort so you can grow. “Look at three things,” Magnus recommends. “One, what do I like to do? No. 2, what does my body need? No. 3, what do I want to master or get better at? That should create your weekly programming.” You already know, and Magnus will remind you, that there are absolutely no life shortcuts to being the superhero of your own life. In this conversation, you’ll find out how much time to spend on your workouts (not as much as you think). “What doesn’t happen in the first hour will not happen in the second,” he says frequently. Even for superheroes. Learn more about Magnus Lygdbäck’s journey from hockey player to celebrity trainer . Find out how you can improve your own performance on Magnus’s extensive YouTube channel . Get Magnus’ superhero training programs, nutrition guides, coaching and a community of like-minded people with the Magnus Method app . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 10, 2023

Today, we’re joined by second-time guest, Dr. Caroline Leaf, to talk about helping kids clean up their mental mess and be more resilient—all based on research from her latest book, How to Help Your Child Clean Up Their Mental Mess. In this episode, Dr. Caroline Leaf shares the best ways for parents to help their kids understand their emotions and build better habits. Dr. Leaf conducts ongoing research and clinical trials in the field of psychoneurobiology in order to improve mental health interventions, many of which she summarizes in this far reaching, informative conversation. We explore the impact of social media on kids’ anxiety, what parents can do to minimize the mental mess social media can make, and even how to rewire neural patterns it forms. We also dive into the myths of habit formation and how we can break down old habits to form better, new ones. Dr. Leaf’s expertise doesn't stop there. She also gives a comprehensive explanation of the five steps of the Neurocycle, a tool set for self-regulation and changing your internal programming. 00:01:32 — The Dangers of Social Media & Minimizing Mental Messes • Giving coffee to kids • Danger Coffee: dangercoffee.com • The mental health crisis kids are facing today • Social media’s role in anxiety in kids • What is a mental mess? • Read: Cleaning Up Your Mental Mess • Avoiding a mental mess while using social media • Read: How to Help Your Child Clean Up Their Mental Mess • How to teach kids to go deep on topics they’re interested in • The science behind how long it takes to build or change a habit 00:27:31 — Habit Hacking 101 • The 5 Steps Neurocycle to rebuild neural networks • The myth of building habits in 21 days • Identifying patterns in habit formation for transforming and healing the brain • How the history of habit formation and brain neuroplasticity has evolved over time • The new standard of care and giving hopeful diagnoses • Empowering ourselves to be the driver of our own health 00:54:37 — Helping Kids Build Resilience • Curiosity as a tool for building resilience in kids • The importance of learning how to self-regulate • How modeling the Neurocycle can help parents and children manage emotions • Why you should double down on what makes you weird • Teaching kids to question everything to filter out what’s real • Removing bias by connecting with others who aren't your age • Helping kids get good sleep Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Read: How to Help Your Child Clean Up Their Mental Mess Read: Cleaning Up Your Mental Mess Website: drleaf.com Facebook: Dr. Caroline Leaf Instagram: @drcarolineleaf YouTube: Dr. Caroline Leaf Podcast: CLEANING UP YOUR MENTAL MESS 5 Steps of Neurocycle Can Clean Up Your Mental Mess – Dr. Caroline Leaf with Dave Asprey – #799 The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 8, 2023

IN THIS EPISODE OF THE HUMAN UPGRADE you’ll learn how to recognize your own sh*t and be a better partner in relationships. Want a sustainable partnership? Communicate and apologize; fight without fighting; identify codependent behavior (your own); and manage jealousy (also your own). This conversation gets into how you can let go of unrealistic ideals of how you think love and relationships should be and live fully in the present. You’ll also get tips on how to be emotionally responsible to people you love every day. Guest John Kim, a licensed marriage and family therapist, as well as a life coach, cracks his life into two big pieces… split on either side of what he calls “the great divide” of his own divorce several years ago. He did the whole “get a tattoo and a Harley” thing to find his way. He also combined what he learned in therapy school with life coaching and technology to be mobile and create online communities. He became known as an unconventional therapist, seeing clients at coffee shops, on hikes, or in a CrossFit box. He’s built a devoted following of fans who love the frank and authentic insights that he—as “The Angry Therapist”—freely shares on social media. TikTok’s his jam, with over 450K people tuning in for his “shot glass” bits of life wisdom. In his book, written with his romantic partner and fellow therapist Vanessa Bennett , John takes a different (honest, humorous, raw) approach by dissecting his own relationship dynamic to bring clarity to yours. Each part of “ IT’S NOT ME, IT’S YOU: Break the Blame Cycle, Relationship Better ” gives you questions to ask yourself and practices to do. It’s a book that pushes you into doing and putting your newfound knowledge to IRL use. Here’s a sneak peek at a few of the Love Lessons (In a Shot Glass) you’ll find in “ It’s Not Me, It’s You .” Love is not a battlefield. Your head is. If someone is unsure about you, it’s never worth the investment. Hold love, don’t grab it. Don’t stop believing (be Journey). Love is what teaches us how to live. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 4, 2023

Today's episode is an Upgrade Spotlight edition, where we bring someone on the show who has created something interesting. Our guest today is Dr. Myles Spar, a leading authority in personalized performance medicine as an author, teacher, researcher, TEDx talk speaker, advisor to NBA players, and an Ironman athlete. In today’s episode, Dr. Spar shares the vast range of benefits of Calroy Health Sciences products, many of which I use in my morning routine, including Arterosil and Vascanox. We talk about the science behind these formulations, and how they help support athletic performance, recovery, cardiovascular health, and even sexual function. If you’re interested in trying these products yourself, you can get a discount off a three-month supply of Arterosil and Vascanox at calroy.com/dave . 00:03:40 — Improve Cardiovascular Health with Vasconox • The correlation between nitric oxide and endurance athletics • Calroy Health Sciences: calroy.com/dave • Vascanox: calroy.com/dave • How nitric oxide supports vascular health • How to collaborate with your doctor 00:13:02 — Spotlight on Nitric Oxide & Hydrogen Sulfide • Nitric oxide and aging • Three kinds of nitric oxide in the body • How nitric oxide helps sexual function • An explanation of hydrogen sulfide’s impact on the body 00:20:46 — Why Investing in Quality Supplements is Worthwhile • Arterosil: calroy.com/dave • Why I invest in 84+ supplements for my morning regimen • The science behind Calroy products • The importance of recovery and optimizing the speed of recovery • Read: Smarter Not Harder • My supplement fix for POTS, Postural Orthostatic Hypotension Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Get a discount off a three-month supply of Arterosil and Vascanox at https://calroy.com/dave Website: drspar.com Facebook: Myles Spar, MD Instagram: @drspar Linkedin: @drspar YouTube: @mdspar The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 3, 2023

Today's episode is a special intervention episode where I work with a member of the Upgrade Collective, my mentorship and membership group, to help them get closer to achieving their health goals. This conversation is all about investigating member Nadya Green’s struggle to lose weight despite following a low carb diet and cycle syncing her eating habits. Nadya, originally from Russia, has spent her life pursuing an international career in the energy sector. She has worked as an engineer around the globe, including the UK, US, Australia, Egypt, Russia and now Sweden. Becoming a mom at 35 years old has made it ever so critical to be fit and to be able enjoy activities with her family, which is why biohacking and weight loss has become a centerpiece in her life. We talk about her lab results that point to potential gut issues, estrogen dominance, and mineral deficiencies leading to her cravings, and why her carbophobia may actually be working against her goals. I share with Nadya tools and tips to illustrate all the different pathways that you can use to get the results you want. So, if you're looking at what could be holding you back in your weight loss journey, tune in to hear the advice I gave Nadya about where she could be going wrong, and what to do to help her feel her best. Join the Upgrade Collective to get access to be in the live audience for all of my podcasts, with calls where we all get together and help each other biohack whatever needs biohacking, at ourupgradecollective.com . 00:01:35 — Why A Low Carb Diet Might Not Help Your Weight Loss Goals • Nadya’s history with extreme fatigue, Hashimoto’s and carbophobia • The impact of the keto diet long-term on metabolism • Toxins related to PCOS and endometriosis • Read: Smarter Not Harder • Environmental & emotional causes of sugar cravings • Symptoms of having active yeast in your gut 00:16:44— Combating Candida: Supplements, Medications & Lifestyle Solutions • Exploring the different ways to combat Candida • My hot take on pharmaceuticals • How to support your detox pathways while on pharmaceuticals • How Candida is related to a sensitivity to cow’s milk • Limiting sugar without eliminating it • Eating what you like in moderation and not being in a perfectionist trap • Cycle syncing your cravings and carbs 00:32:05 — Eat to Feel Amazing: Spotlight On Protein & Minerals • Protein types and amount recommendations • The Bulletproof Diet: daveasprey.com/roadmap • Why new mothers need to pay more attention to their mineral levels • Tps for getting enough electrolytes and offsetting mineral deficiency • Why I recommend eliminating dairy to combat fatigue or brain fog • Helpful supplements for estrogen dominance Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Biohacking Conference: https://www.biohackingconference.com/ Join the Upgrade Collective: https://www.ourupgradecollective.com/ The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 1, 2023

Our guest today is a legendary thinker, author, and philosopher. Ken Wilber has spent decades understanding how humans are all interconnected with each other, decoding through dozens of beautifully written books, how we fit into the greater, massive, picture that is the expanding universe. He's an absolute pioneer, a visionary, and that barely scratches the surface of his work. He joins Dave to outline his newest book—Finding Radical Wholeness: The Integral Path to Unity, Growth, and Delights—and offers up a supporting stream of consciousness which rivals any that you’d find, on any podcast, in depth of insight and emotional impact. His words resonate with a truth and wonder which will leave you inspired from beginning to end, and well beyond. 00:00:38 — Finding Radical Wholeness with Ken Wilber • Ken Wilber’s Amazon Author Page • Different ways to explain the general ideas of the world • Read: Finding Radical Wholeness: The Integral Path to Unity, Growth, and Delights • Achieving wholeness in our day-to-day • Ken’s first experience of wholeness with the universe • Does a dog have Buddha-nature? • Studying the work of D.T. Suzuki as a young boy • Read: Essays in Zen Buddhism by D.T. Suzuki • Oneness experiences as the core of spirituality • Considering satori as the most precious gift that humankind has 00:18:09 — The Roles Biohacking & Brain Stimulation Play in Unity Experiences • Electromagnetic brain stimulation for ultimate reality experiences • How brain-mind machines work • Tap Into Your Brain’s Full Potential - Patrick Porter, Ph.D. #869 • How Dave wrote The Bulletproof Diet in gamma state • What the mind does vs. what the heart does • Ken’s favorite advancements in technology • Questions remain with regard to quantum unity • Explaining the theta formless state • The Science of Changing Your Mind - Dr. Joe Dispenza #980 00:38:10 — States of Emptiness & How To Get There • Teachings of Nagarjuna • Formulating the quantum principles • Why all forms of thinking are incomplete • The four-quadrant pronouns that make it all make sense • Basic tenets of integral theory • Shared objective views, social organism or a collective group • Going deep with Ken Wilber • Are we living in a simulation? • Fourth and fifth states of consciousness 01:08:55 — This is Ken Wilber on Drugs & Nonduality • Psychedelic experiences vs. mystical oneness experiences • Drugs as a shortcut to masterful meditation • Ken’s bad trip • Stan Grof’s early LSD work • The Birth of LSD with Dr. Stanislav Grof, Father of Transpersonal Psychology - #428 • Failures of the psychedelic revolution • Dave’s hand in the ayahuasca boom • Ken Wilber’s awe-inspiring perspective on nonduality • Read: Finding Radical Wholeness: The Integral Path to Unity, Growth, and Delights • Outline of Ken’s latest book • Stages of operational thinking • Introduction to systems theory • Appreciating the psychosomatic analysis of Fritz Perls Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Read: Finding Radical Wholeness: The Integral Path to Unity, Growth, and Delights Read: Amazon Author Page YouTube: Integral Life The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 27, 2023

In this episode of The Human Upgrade you’ll meet a holistic neurosurgeon who’s evolving spine care away from cutting. Dr. Marcella Madera’s integrative approaches to spine problems pair science with holistic healing modalities. This means way better healing for you. Dr. Madera’s innovations in spine treatments include the “Aqua Method,” where photobiomodulated platelet rich plasma meets functional tissue mobilization and movement. You’re going to get exciting new information about this effective form of regenerative medicine and find out if this treatment may be right for you. “It's a very nuanced discussion,” says Dr. Madera. “It's very patient specific. It's very injury specific.” “The term Aqua really gives a description of what we're trying to create in the body and that is more fluidity,” she explains. “And also, water, aqua, is pure. It’s intense at times, depending on the form. And it is soothing at times, depending on the form. And that is how our treatment goes.” Dr. Madera’s four-part system includes: Reveal, Restore, Revitalize, Revel. You could benefit whether you have an old or new injury, or chronic pain. During this episode, she explains how each part is interconnected and helps you heal your spine, or even knee, problems. The Aqua Method’s three-day immersive experience includes a full team of experts focused on your biology, your energy and your state of mind. Dr. Madera, a board-certified neurosurgeon, trained extensively in conventional medicine. Her expertise in spine care includes surgical treatments, approaches, and techniques for degenerative spine disease, spine tumors, and degenerative deformity. She started a private practice in in Austin, Texas where she combines her technical spine care with stem cell treatments and holistic modalities like herbs, energy modalities, Chinese healing practices, autogenic training and diet modification. More about Dr. Marcella Madera: She’s experienced in open surgery, minimally invasive surgery, endoscopic spine surgery, and regenerative/stem cell procedures. She’s been an assistant professor of Surgery at the University of Texas at Austin Dell Medical School. She also travelled throughout Europe and the U.S. to learn progressive endoscopic techniques and regenerative medicine practices. She completed a Spine Fellowship and faculty instructorship at Johns Hopkins School of Medicine. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 25, 2023

In this episode of The Human Upgrade you’ll find out how to harness the power of your inner voice to ease anxiety, improve physical and mental health, and deepen your relationship with others. “The mind is flexible, if we know how to bend it,” says psychologist and award-winning professor Ethan Kross, Ph.D., founder of the Emotion & Self Control Laboratory at the University of Michigan. He’s one of the world’s leading experts in controlling the conscious mind. He studies the ways in which your inner voice impacts your health, performance, decisions and relationships. He explores how people manage their emotions in order to better understand self-control. In particular, the conversations you have with yourself directly impact every part of your health and life. He explain that your inner voice functions to do things like this: Keep information active in your mind Coach you through problems Simulate and plan ahead Tell you stories That inner voice can be a powerful tool, giving you creativity, connection and definition. However, when the voice turns to negative and disorienting self-talk (chatter), it can create chaos and overwhelm by zooming into our problems, making you lose perspective. Ethan’s pioneering research mixes behavioral and brain research to get at the “why” behind human nature. He uses insights from his research to give people science-based tools they can use to change their behavior, be used in relationships, support a career move, improve physical performance, decrease stress, increase productivity and be used to reach life goals. You’ll use new tools like mental time travel, tough love and introspection. In this conversation about his book, “CHATTER: The Voice in Our Head, Why It Matters, and How to Harness It, ” you’ll learn: How social media plays a part in our chatter How to zoom out with a flexible mind, changing thoughts and distancing ourselves How to use tough love How to teach your kids about chatter from a young age How to help your friends with their own chatter (and what makes it worse) With Ethan’s experience studying the conscious mind for 20 years, you can learn how to turn negativity into an awesome tool that helps you master your own self-talk. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 20, 2023

Today, on The Human Upgrade, we talk to Steve Revelli about the long history and bright future of using silver nanoparticles as a biohacking silver bullet. Steve's background is in science and education, now serving as the QA Manager at American Biotech Labs, LLC, the brand which produces Silver Biotics—a long-time resident of my own medicine cabinet. The conversation covers the difference between pathogenic bacteria and probiotics, how silver under a concentration of 40 parts per million can target harmful bacteria while leaving healthy probiotics intact, the importance of nanoparticle size, antibiotic resistance, animal and agricultural applications, and so much more. You will learn how they use silver in the world of medicine (because they actually do and have for more than a hundred years) and how/when to use it yourself, whether topically, supplementally, or otherwise. This, my free-thinking friends, is a masterclass in using silver for biohacking. 00:03:06 — Retelling the Long Story of Silver • Historical meaning of “born with a silver spoon” • Microbial elements of AG404–why it works • Chemistry deep dive, searching for missing electrons • Why doesn’t silver attack healthy cells? • Differences between prokaryotic cells • More is not always better 00:11:22 — Delivery Systems to Improve Your Health • Importance of nanoparticle sizes in effective use • One warning: avoiding high salt • Using AG404 in nasal spray during air travel • Other off-label uses for Silver Biotics • Silver particles for immune support • Topical use for fighting infection • 70-year medical history of using silver for burns • Using a vertical sprayer for delivery • Code: DAVE for 30% off at silverbiotics.com 00:27:09 — Cosmetic Benefits & Antibiotic Resistance • New formulations from Silver Biotics • Wrinkles, acne, cuts, scrapes, etc. • Facial serum vs. skin cream • Fighting antibiotic resistant bacteria • Pet care and successful applications in agriculture • Safety an ingestion cycles • Turning blue from silver toxicity • Relieving bacterial burden from your sinuses • Code: DAVE for 30% off at silverbiotics.com Resources • Shop: Use code DAVE for 30% off at silverbiotics.com • Instagram: @silverbiotics The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 18, 2023

Today, we're delving deep into the importance of dirt, not just as soil beneath our feet, but as a key factor in regenerative agriculture and biohacking. Our guest, Andrea Bemis, is an expert in sustainable organic farming and a passionate advocate for nurturing healthy babies and children. Together, we explore the power of the family dinner and the significance of avoiding harmful chemicals and additives in the food we provide for our kids. Andrea Bemis, the brilliant mind behind the farm-to-table blog "Let Them Eat Dirt," joins us as our special guest. She has authored remarkable books, "Dishing Up the Dirt" and "Local Dirt," which provide invaluable insights into creating a healthy and nourishing food environment for children. Through our shared belief in empowering kids to make healthier choices, we aim to guide parents away from the junk and chemicals that can harm their children's well-being and towards more sustainable, locally sourced and economical options. Join us as we share our tips and tales from our own dinner tables, and our top strategies for nourishing your children with whole foods that taste good, too. Welcome, Andrea, to The Human Upgrade. 00:02:07 — Avoiding Processed Foods: Dangers of Heavy Metals & Artificial Sweeteners • How processed foods can change brain chemistry • The mistake parents of young children make when it comes to food • Tips for getting kids to eat diverse foods and flavors • Logistics of living on a farm • Benefits of buying from a CSA • The Baby Food Facts Report findings on sweeteners in baby food • Heavy metals in baby food 00:21:01 — Healthy, Fast & Economical Recipes for Kids • Most economical ways to make healthier baby food at home • Recommended cooking oils for kids and why • Being mindful of how much kids are snacking • Not forcing your kid to eat when they’re not hungry • Andrea’s fast recipe ideas • How salt impacts babies’ digestive system • Read: Nourishing Traditions by Sally Fallon 00:43:45 — Andrea’s Favorite Sweetener & Farm Life Insights • Andrea’s favorite sweetener for kids • Pros and cons of kale • Finding quality bacon • The most difficult crops to grow • Teaching your kids where food really comes from • Why small farms are so incredibly important & economical Resources • Website: dishingupthedirt.com • Instagram: @andreabemis • CSA: gotumbleweed.com • Read: letthemeatdirtkids.com The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 13, 2023

Today, a dear friend of the show and someone who's disrupted a huge part of the healthcare industry joins us for an informative chat on the critically important oral microbiome—and from a wider perspective—how and why the human body gets sick. Naveen Jain, founder of Viome—a data company that’s changing the world of health and wellness—goes deep on the latest in anti-aging, what's going on in your mouth and how that affects everything else in your body, the perils of mouthwash, the future of AI-powered analytics, business building with the right priorities in mind, and a whole lot more. And it all comes right back to the base definition, the core understanding, of what biohacking is—using the information and technology around us to live a longer and healthier life. Naveen’s company, Viome, is doing just that. You won’t want to miss this exclusive look into the future—for your own long-term health, or for that of society as a whole. 00:01:44 — What Is It About the Human Body That Causes Us To Be Sick? • Fundamentally changing the way we look at the body • Dave’s homemade mouthwash and why he stopped using it • Power of individuality when it comes to health and longevity • Different impacts of foods on identical twins ( Research ) • What happens in the gut, starts in the mouth • The signals chewing your food sends to your body • Why a healthy oral microbiome means healthy sex 00:09:33 — Viome: Supercharging Human Data Analytics • Reading out the transcript from your body • Determining a diet-based source of bad breath • Viome’s biomarkers and aging score • Looking at RNA va. DNA • Shop viome.com and use code DAVE10 to save 10% • Pooling the data from 550,000 samples analyzed • Custom-made diet recommendations for your genetics • Affordability of Viome testing kits • Predicting mouth and throat cancer at a 95% rate • Personalized oral microbiome toothpaste gel 00:24:13 — Longevity & Lifespan: Our Health Is Our Wealth • Increasing our healthspan—adding truly viable years • Dave calls out the lifespan cowards • Choosing how and when we die: the ultimate goal for society • Naveen shares 5 ways to live a long and healthy life • Nutrition, getting the right fuel for the car • Stress management, escaping fight-or-flight mode • 40 Years of Zen neurofeedback therapy • Why you should quit your shitty stressful job • Smarter Not Harder by Dave Asprey • Prioritizing exercise, 30 minutes a day • Getting proper sleep, quality vs. quantity • Sleep with Dave: 14-day sleep challenge 00:37:35 — A Message for the World’s Wantrepreneurs • Find a purpose and live 10 to 15 years longer • Focus on helping people live better—not making more money • Parasitic nature of modern commerce • Amazon’s quality spiral and the race to the bottom • Impacting the world in your uniquely powerful way • Our success will never be defined by how much money we made Resources Instagram: @viome Instagram: @naveenjainceo Viome: viome.com (Code DAVE10 to save 10%) Website: naveenjain.com The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 11, 2023

IN THIS EPISODE OF THE HUMAN UPGRADE™️... Sadhguru, a yogi, mystic, visionary and spiritual master who spreads wisdom around the world, clarifies the meaning of karma (no, it’s not a checklist of good and bad deeds) and explains how much you’re in charge of your own karma. His most recent book, “ Karma: A Yogi’s Guide to Crafting Your Destiny ,” breaks down the ways in which karma frames our lives. “It’s time to unpack the most overused, abused and yet indispensable world in the spiritual vocabulary of the world,” says Sadhguru in his book. “It is time to examine how karma is connected to some of the most vital areas of human inquiry: the meaning of life and above all, how to live it.” See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 6, 2023

IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... “Americans are the unhappiest they have been since the Great Depression,” says Dr. Daniel Amen. But he’s determined to change that. He’s a physician and double board-certified psychiatrist who looks at happiness as a brain function. After studying more than 200,000 brain scans of people from 155 countries, Dr. Daniel Amen discovered five primary brain types and seven neuroscience secrets that influence happiness. “I wanted to spend my time and energy and research on happiness because, ultimately... happiness is a moral obligation because of how you impact other people,” Dr. Amen says. “The big central point [is] the brain is the organ of happiness, and if your brain is not healthy, you are not likely to be happy.” What makes you happy? The answer lies in knowing your specific brain type and how it’s being influenced by seven specific chemicals. Happiness originates in distinct brain regions: pleasure in the orbitofrontal cortex; motivation and habit formation in the basal ganglia; and mood and cognitive flexibility in the brain stem. You may be one or a combination of these five primary brain types: ( take this brain assessment to find out yours ) Balanced : you have a very healthy brain Spontaneous : you have low dopamine Persistent : you’re often worried, rigid, and inflexible Sensitive: you need other people and isolation is hard Cautious: your GABA levels are low Learn more about brain types and what actually boosts your happiness according to neuroscience in Dr. Amen’s book, " You, Happier: The 7 Neuroscience Secrets of Feeling Good Based on Your Brain Type .” “Happiness comes from moving your life forward toward your life goals with meaning and purpose, based on your values, despite whatever obstacles are in your way,” Dr. Amen says. “A happy life doesn’t focus on the past with regret or look to the future with fear.” See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 29, 2023

If you have all sorts of unexplained health problems in your home, where you work, or where you go to school, symptoms can be very different. One person's gaining fat, another person's always tired, other people have dark circles, emotional irregularity, sudden weight gain, onset of allergies that no one can explain, on and on. In the episode today, you learn the smarter, not harder, ways to deal with toxic mold exposure in your environment from one of the world’s leading experts on the matter. Our guest is Brian Karr. He's a second-generation indoor environmental consultant and he works with hypersensitive individuals with complex medical conditions. He's the co-founder of We Inspect, an environmental testing company which works to help people understand mold, mycotoxins, and even bacterial toxins that exist in your homes. He takes time to explain what's (usually) there, why it’s important—even down to the genetic level—and what it's doing to you. Go back to the definition of biohacking… The art and science of changing the environment around you and inside of you so that you have full control of your own biology. If your environment is moldy and has biotoxins, maybe you don't have control of your biology—the mold does. Brian's become a go-to guy for medical doctors across the country, helping more than 5,000 people as sensitive as I used to be to create healthier living environments. You're going to learn a lot in this episode, even if you're saying… Well, I don't have a mold problem. You'd be very surprised. 00:17:00 — Meeting the Mold (and Brian) Head On • Dave’s younger years battling his own health • The xenoestrogen that took over his life • Brian Karr’s background and introduction • We Inspect environmental testing company • Moldy Movie: moldymovie.com • How Brian married into the business and fell in love • Building an infrastructure to serve the country • Betsy Maldonado’s story 00:15:02 — We Inspect: Spotlighting Innovation & Access • We Inspect ’s process—what’s unique and special? • Most mold is hidden out of plain sight • Perils of dry mold: more mobile than wet, living mold • The importance of knowing what to look for • Prioritizing innovation and accessibility • Training program: Mold Finders Method • Mobile app: We Inspect Together • Pitfalls of other, commercially driven services 00:29:18 — Dealing With Mold in Our Day to Day Lives • Brian’s game plan for getting out of a moldy lease • Does spraying bleach work? • Why Dave avoids AirBnbs • Homebiotic: homebiotic.com • Balancing removal options • Three easy steps to take in your home • Understanding the Human Cloud Effect • Gaps in capability of air testing • Effectiveness of dust sampling • Find Out If Your Home Is Making You Sick • 100M structures in the US have meaningful mold problems 00:50:04 — Looking Ahead At Life With Less Mold • 90% of structures are exposed to toxic mold • Danger Coffee: dangercoffee.com • What is truly pure? • Balance of bacteria vs. mold in caves • Added susceptibility of women and children • 40% of population impacted by mold exposure • Story time: Dave’s mold-triggered PANDAS WE LOVE OUR SPONSORS! CHECK THEM OUT: • We Inspect environmental testing company • The Dust Test: thedusttest.com/dave • YesWeInspect.com/Dave • Moldfinders on Instagram • Brian Karr on LinkedIn • Moldfinders on Facebook • Moldy Movie The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 27, 2023

In this special episode of The Human Upgrade LIVE from the 9th annual Biohacking Conference in Orlando Florida, Dave speaks Vera Mulyani, co-founder of Astrobiome and Mars City Design. Vera discusses the connection between biohacking and living on Mars and emphasizes the importance of designing the Martian environment to control human biology, taking into account mental health and architectural expertise. They also highlight challenges like toxic chemicals in spacecrafts and the need to biohack humans for space. Vera introduces Astrobiome, a microbiome product made from fermented bacteria, designed to optimize gut health in extreme conditions. Success stories demonstrate its effectiveness in improving health and performance. The podcast explores the intersection of biohacking, space exploration, and the significance of microbiome health in Mars-like environments. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 22, 2023

In this special episode recorded live from the 9th Annual Biohacking conference in Orlando, Dave dives into the vegan vs. animal protein debate with Max Lugavere and Dr. Amy Shah. They explore the reasons behind choosing a vegan lifestyle, including health, reducing animal suffering, and environmental concerns. Max defends animal protein, highlighting its efficiency and amino acid bioavailability, while Dr. Amy advocates for a balance between plant and animal protein, emphasizing the importance of plant fiber for gut health. They discuss studies linking meat consumption to cardiovascular disease and share their personal experiences, ultimately encouraging listeners to find their own balanced approach to protein. They also delve into topics such as protein intake, muscle building, longevity, fasting, circadian-style eating, and the impact of carbohydrates on the body. 9th Annual Biohacking Conference: You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. https://biohackingconference.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 20, 2023

In this episode, Dave Asprey interviews sex expert Emily Morse about her book "Smart Sex: How to Boost Your Sex IQ and Own Your Pleasure." They discuss the importance of regular date nights for couples and overcoming shame to talk about sexual fantasies. Emily suggests using the "yes/no/maybe" list as a fun way for partners to explore their desires. Real-life examples show how couples transformed their sex lives by addressing physical and emotional challenges. They also touch on therapeutic approaches and the impact of diet on sexual health. Overall, "Smart Sex" offers practical advice for enhancing relationships and enjoying fulfilling sex lives. Watch this episode on YouTube . Find all the links and resources in the show notes . Check Out Emily's new book " Smart Sex " See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 15, 2023

In this episode of "The Human Upgrade with Dave Asprey," Dave welcomes Kashif Khan from the DNA Company. Kashif shares his journey in functional genomics and how he unintentionally reversed his biological age by 10 years. They discuss the importance of understanding your genome and its impact on aging. Kashif highlights the DNA Company's approach to genetics, focusing on identifying biological functions and finding personalized solutions. They explore the connection between genetics, habits, and aging, emphasizing the need for context-based choices. Kashif also reveals how his genetic profile influenced his gut health and neurochemical balance. Finally, they touch on the role of upbringing and lifestyle in overall health. Don't miss this insightful conversation on unlocking the secrets of functional genomics for a healthier, rejuvenated life. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! The DNA Company: https://www.thednacompany.com 9th Annual Biohacking Conference: You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. https://biohackingconference.com If you’re coming to the conference, after Kashif’s session he will be signing copies of his new book, “The DNA Way: Unlock the Secrets of Your Genes to Reverse Disease, Slow Aging, and Achieve Optimal Wellness.” See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 14, 2023

In this episode of "The Human Upgrade with Dave Asprey," Dave discusses the concept of earthing or grounding, a practice he introduced during the early days of the biohacking movement. He explores the benefits of earthing in reducing inflammation and jet lag. Dave introduces Christie Hardison from Anti Aging Bed, who explains their innovative product that combines earthing, photobiomodulation, and antimicrobial silver technology. The bed cover allows users to ground themselves while sleeping, protects against pathogens and EMFs, and uses tourmaline crystals for infrared simulation. Dave and Christie delve into the connection between earthing and other biohacking practices like ozone therapy and the importance of REM sleep. Christie will be speaking about earthing and the Anti Aging Bed at the Biohacking Conference in Orlando. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Anti-Aging Bed: https://antiagingbed.com 9th Annual Biohacking Conference: You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. https://biohackingconference.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 13, 2023

We're previewing the 9th annual Biohacking Conference in Orlando Florida (June 22 - 24) on The Human Upgrade! In this episode of "The Human Upgrade with Dave Asprey," Dr. Jason Sonners discusses hyperbaric oxygen therapy and its connection to scuba diving. He mentions his own experience with scuba diving and the therapeutic benefits he believes it offers. Dr. Sonners also talks about ongoing research with a diver staying underwater for 100 days and predicts changes in hormone levels, DNA methylation, and inflammation. They discuss the importance of pressure in hyperbaric therapy and the potential for personalized protocols based on individual needs. The experience of being in a hyperbaric chamber is described as comfortable, relaxing, and mostly involving equalizing pressure in the ears. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! OxyHealth Hyperbaric Chambers: https://www.oxyhealth.com 9th Annual Biohacking Conference: You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. https://biohackingconference.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 12, 2023

We're previewing the 9th annual Biohacking Conference in Orlando Florida (June 22 - 24) on The Human Upgrade! Patrick K. Porter, PhD has dedicated his life to studying neuropsychology. For years it was believed that we have a set number of brain cells, that our intelligence quotient is fixed, and that our brains do not change. Dr. Porter’s clinical experience and research told a different story, revealing that the human brain is, in fact, plastic, making it capable of change, improvement, and expansion. Patrick’s discoveries led him to develop the BrainTap headset, sparking incredible transformation for thousands of people. In 2014, with the emergence of the Apple and Android mobile platforms, he saw the opportunity to impact millions more by bringing this technology to an app. Thus, the brain fitness company – BrainTap – was born. BrainTap has proven that your brain can be retrained to operate at its best and that it’s never too late to tap into your brain’s fullest potential. With its state-of-the-art headset and a suite of more than 1800 sessions that range across dozens of desired life outcomes, the company has made great strides in revitalizing the mental clarity, confidence, and energy of extraordinary individuals worldwide. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: https://braintap.com/dave 9th Annual Biohacking Conference: You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. https://biohackingconference.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 8, 2023

America is back on the map as a global leader in stem cell technology, thanks in huge part to these two FDA-conquering innovators. Sean Berman and Kevin Ferber talk about the past, present, and future of stem cell therapy – and where, why, and how to bank your own healthy cells ASAP. Watch this episode on YouTube . Find all the links and resources in the show notes . WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! American Cell Technology: https://americancelltechnology.com/dave/ California Stem Cell Treatment Center: http://CaliforniaStemCellTreatmentCenter.com BioHacking Conference 2023: https://americancelltechnology.com/biohacking2023/ California Stem Cell Treatment Center: http://CaliforniaStemCellTreatmentCenter.com Sleep Solutions for High Performance: https://sleepbreakthrough.com/dave , use code DAVE10 to get an extra 10% off 9th Annual Biohacking Conference: You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. https://biohackingconference.com The Human Upgrade is produced by Crate Media . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 6, 2023

Today’s show gets into DNA, genetic codes, consciousness, energy, and BioQuantum Skincare. Jewels Arnes comes on today's show to make sense of it all and make some cool connections between those things for you. Her expertise includes three decades of energy medicine, vibrational healing, and intensive consciousness work. She pairs that work with creating tangible products, like the BioQuantum Skincare Technology, the Scalar Cosmetic Line, and an EvoStar Quantum App. In this episode, you’re going to learn how BioQuantum Skincare enhances DNA & telomere health, how to use the products to treat skin conditions, how to advance the consciousness of the products, and how to advance skin health with no products at all. There’ll be some discussion of breaking quantum physics in here, too. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Website : https://bioquantumskincare.com/DAVE Jewels Arnes Talks Breaking Quantum Physics Instagram: https://www.instagram.com/bioquantumskincare/ Facebook : https://www.facebook.com/bioquantumskincare YouTube : https://www.youtube.com/@bioquantumskincare Jewels Arnes: https://jewelsarnes.com Activate Evolution : https://activateevolution.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 1, 2023

Nayan Patel, PharmD recently published his first comprehensive book, “The Glutathione Revolution: Fight Disease, Slow Aging & Increase Energy.” After 14 years of clinical research on the master antioxidant, glutathione, Dr. Patel finally shares how powerful and essential glutathione is to the body’s detox system. He speaks about the various benefits it has with slowing the aging process down, and explains how you can increase your levels naturally. Dr. Patel is a firm believer in providing the body with tools it needs to defend itself and promote a healthy lifestyle that fits the pace of the modern world. Nayan Patel, Pharm.D is globally regarded as the foremost go-to expert on absorbable forms of glutathione, and holds the only patent on transdermal glutathione. Along with traveling the world educating practitioners on advanced biochemistry and anti-aging science, Dr. Patel also serves as adjunct faculty at the University Of Southern California School Of Pharmacy where he is also an alumnus. 9th Annual Biohacking Conference: You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. https://biohackingconference.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 25, 2023

Mario Brainovic is an expert in the science of water, specifically focusing on its ability to transmit energy, frequency, and vibration. With a wealth of knowledge and extensive research under his belt, Mario has dedicated his work to understanding the profound changes that can occur in our biology when we consume water that has been treated with the right frequencies. As the CEO of Analemma, Mario has developed a unique approach to creating positively charged water that can boost our physiology and overall health. This friendly and passionate water enthusiast is always eager to share new findings and discoveries to help others optimize their energy levels. Find all the links and resources in the show notes . WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Must-Have Magnesium: https://magbreakthrough.com/dave , use code DAVE10 to get a 10% discount Biohack and advance your skincare to the next level with https://bioquantumskincare.com/ use code DAVE22 for 22% OFF 9th Annual Biohacking Conference: You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. https://biohackingconference.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 23, 2023

Looking for a more balanced and fulfilling life? A life where you prioritize your own self-awareness and holistic wellness? Well, Jason Wachob has the solution to help you achieve optimal health and vitality through a mindful and prioritized approach to your well-being. In this episode, Jason will teach you how to fortify your emotional well-being by fostering social connections and community ties. Enhance the environment through the adoption of regenerative agriculture and sustainable farming techniques. Discover happiness and significance by focusing on the crucial aspects of life. Fine-tune your diet by paying attention to your body's unique needs for optimal health. Watch this episode on YouTube . Find all the links and resources in the show notes . WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Shield Yourself from EMFs: https://quantumupgrade.io , use code DAVE to get a two-week free trial Sleep Better on Natural Memory Foam: https://myessentia.com/daveasprey , use code DAVE to save. 9th Annual Biohacking Conference: https://biohackingconference.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 19, 2023

Genpo Roshi, the respected spiritual leader with a wealth of experience in Zen practice and personal growth, is back in this legacy upgrade episode. In this episode, you will uncover the wisdom behind Genpo Roshi's views on Zen and meditation on your path towards enlightenment. Master the skills of non-judgmental relaxation techniques to enhance inner peace. Combine the power of deep relaxation, Big Mind process, and koan practice for a holistic meditation experience. Discover the keys to lasting happiness by embracing freedom and giving up the pursuit of external factors. Listen in to learn how to cultivate personal growth through self-care practices, valuable introspection, and fostering healthy relationships. Get all the links and resources in the show notes . WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Get your tickets to the 9th Annual Biohacking Conference: https://biohackingconference.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 18, 2023

What if everything you perceive is just a construction of your brain? In this episode, Anil Seth and Philip Goff explain how our perception of reality is a product of our minds and how it can be manipulated. They also delve into the implications of these findings, and take a dark turn, leaving you questioning everything you thought you knew about yourself and the world around you. Get ready to dive into the fascinating world of perception and consciousness with our guests Philip Goff and Anil Seth. Together, they're here to unravel the mysteries of how our brains construct our conscious reality. Tune in to explore panpsychism and its fascinating connection between consciousness and matter. Gain an understanding of how our brains craft our conscious reality through the intricate process of perception. Acknowledge the limitations of traditional views on consciousness while considering the perks of embracing panpsychism. Master the art of training perception for practical applications rather than perfect accuracy. And most importantly, discover insightful tools for probing consciousness, such as meditation and introspection. Get all the links and resources in the show notes . WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Could this Saturated Fat be the missing link in longevity research? Go to https://fatty15.com and use code DAVE15 to save $15. Customized Nootropics for Your Own Neurochemistry : https://nootopia.com/dave , use code DAVE10 to get 10% off Electrolytes That Taste Good With Zero Sugar Hydration: https://drinklmnt.com/dave , get a FREE LMNT Sample Pack See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 16, 2023

Nancy Sheeber, a talented actress and designer who's been around the block in the entertainment industry gets deep with Dave about how to achieve the most conscious and self-sufficient death. Also, explore why despite your efforts in following strict diets, rigorous exercise routines and experimenting with various biohacking techniques, you're still struggling to achieve optimal health. In this intervention, you will learn to appreciate the power of community in realizing optimal health. Find out about the significance of a balanced Omega 6 and Omega 3 diet for your well-being. You will also identify the benefits of addressing your ego in pursuing personal growth. You will also learn techniques to investigate cutting-edge approaches for attaining maximum wellness. Watch this episode on YouTube ! Find all the links and resources in the show notes . WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Join us at the 9th Annual Biohacking Conference : https://biohackingconference.com Capture Life Force Energy: https://leelaq.com , use discount code DAVE10 to get 10% off sitewide See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 11, 2023

Unravel the insights and wisdom shared by two legendary guests: Mr. Olympia Frank Zane and renowned strength expert Ben Pakulski. Frank Zane is an American former professional bodybuilder, author, and coach who has left a lasting impact on the fitness world. With a focus on symmetry and proportion, Frank's physique earned him three Mr. Olympia titles and the nickname King of Aesthetics. Today, at 75 years old, he continues to offer personal coaching, training programs, and seminars to share his vast knowledge of bodybuilding and fitness. Ben Pakulski, a recently retired professional bodybuilder and former Mr. Canada. Ben is on a mission to educate people globally on a holistic approach to muscle building, empowering them to change both their body and mind. Throughout this combined episode, we explore the shared principles that underpin these two remarkable journeys. From the importance of discipline, focus, and perseverance to the significance of customized nutrition and training plans, our guests leave no stone unturned in their quest to unlock human potential. Check out this enlightening and transformative exploration of the science of the perfect physique and the reimagining of strength training, guided by the wisdom of Frank Zane and Ben Pakulski. Prepare to unlock your true potential and unleash the power within. Find all the links and resources in the show notes . WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Anti-aging Powerhouse : https://spermidinelife.us/dave , use code DAVE25 to save 25% on your first purchase 9th Annual Biohacking Conference: Come join like-minded people June 22-24 in Orlando, Florida. https://biohackingconference.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 9, 2023

Learn how to biohack your mobility, create a movement-rich environment, and tap into the benefits of breathing, sleep, and balance. Kelly Starrett knows all the best moves. His 10 Vital Signs give you doable tests, tips, and tools so you can live your life exactly the way you want to. That means a focus on mobility and your body’s complete range of motion. Movement like being able to sit on the floor and get back up; daily walking and squatting; increasing range of motion in your hips; and mobilizing your back and shoulders. You'll find it all in his newest book (co-authored with his wife, Juliet) “ Built to Move: The 10 Essential Habits to Help You Move Freely and Live Fully .” Physical therapist Dr. Kelly Starret is a highly respected expert in the world of functional movement and mobility. His ability to convey complex ideas in a relatable and approachable manner has made him both a pioneer and a popular figure within the fitness industry. In this episode, he discusses the importance of shifting away from solely traditional exercise and hour-long gym sessions. Instead, Kelly put the focus on movement quality and variety with physical practice happening over 24 hours for a more holistic approach to fitness. " Built to Move " lays a movement foundation for everyone from non-exercisers to professional athletes and everyone in between. “At the heart of upgrading is this idea that you are actually in charge of your own body,” he says, “And that happens in the household. No one else is coming to save you!” Watch this episode on YouTube ! Find all the links and resources in the show notes . WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Must-Have Magnesium: https://magbreakthrough.com/dave , use code DAVE10 to get a 10% discount 9th Annual Biohacking Conference: You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. https://biohackingconference.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 5, 2023

Learn how to tune into your true self and inner power by harnessing quantum energy to ward off EMFs and increase your energetic vibration. Quantum Upgrade sponsored this episode. Founder and CEO, Philipp Samor von Holtzendorff-Fehling, shares how you can reduce EMFs and increase quantum energy in your personal spaces. He joined the show previously to bring you the science and benefits of quantum energy and energy frequencies. You’ll want to take a listen to episodes #890 and #1013 to learn more. This time, he explains how you can harness quantum energy via a remote service. Skeptical? Here’s how it all works. Through years of research and development in tandem with its sister company, Leela Quantum , Quantum Upgrade has created a powerful source of usable quantum energy. By using quantum entanglement, Quantum Upgrade has been shown to improve the function of heart rate variability, ATP production, and blood, among other things. Philipp mentions a recent study that found this quantum technology increased cellular activity by 20%, which has implications for athletes—a bioenergy-hacking tool!—and wound healing. Everyday EMF radiation creates incoherent frequencies that put stress on the human body. This creates biological disharmony and depletes you of quantum energy. The Quantum Upgrade technology “tunes” your environment to surround you with optimal level of usable quantum energy—at all times. When you join the subscription service, Quantum Upgrade “associates” you, your home, phone, business, or even your pet with this energy source. The remote service has been tested through randomized sham-controlled double-blind studies, and Quantum Upgrade has worked with independent testing institutes and labs to test their products. Whether you’re new to exploring the benefits of quantum energy or already have some experience with quantum frequencies, there’s a subscription fit for you. Watch this episode on YouTube ! Find research, links, and resources in the show notes . SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://quantumupgrade.io and use the code DAVE to get a FREE 15-day trial of the Quantum Upgrade subscription service. Also check out Quantum Upgrade and Leela Quantum at the 9th Annual Biohacking Conference: https://biohackingconference.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 4, 2023

Learn about the roots of drama addiction, how it harms the mind and body, and how to recognize signs of it in yourself and others. If you’re on drama overload or someone close to you plows through your life dragging drama everywhere—it’s sucking the energy out of you. News, world events, and social media can cause a firestorm of drama, too. All of it causes physiological and mental chaos that weakens your resilience to life’s real stressors. In this conversation, you’re going to learn what causes someone to develop a drama addiction, some of the main symptoms of drama addiction, and ways to heal from it and keep it out of your life. Holistic psychologist and educator Dr. Scott Lyons joins the show to talk about the pain, limiting beliefs, and trauma that show up in you and others who may have drama addiction. He focuses on what drama addiction actually is and how it can affect your mind, body, and life perspective. Drama has become a global drug, where people are overstimulated and under-connected. Stress, too, plays a surprisingly large role in drama addiction. Other things you’ll learn about drama addiction: What feeds and feels good about it. How trauma influences it. How weaponized empathy poses a danger to your personal life and work life. How to create boundaries with a drama addict. How to thrive if there’s a drama addict in your environment. How to move from drama bonding to more authentic relationships. Scott’s identified nearly a dozen addicted-to-drama archetypes in his new book, “ Addicted to Drama: Healing Dependency on Crisis and Chaos in Yourself and Others .” You may see yourself or others in one or several of them—and that’s good—because then you can move into healing. He outlines a very action-oriented approach with 1) help questions, 2) observation & practice, 3) self-healing statements, and 4) things a therapist might suggest. Not sure how to recognize drama in yourself or the people in your personal or work life? Start by taking Scott’s drama quiz . Watch this episode on YouTube ! Find all the links and resources in the show notes . WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Minerals for Critical Cellular Support : https://www.beamminerals.com , use code DAVE20 to get 20% off 9th Annual Biohacking Conference: https://biohackingconference.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 2, 2023

David Nurse knows exactly what’s holding you back from reaching your goals—taking action. And you’re about to be introduced to the nine action archetypes that explain your lack of follow-through. You’ll learn to identify your archetype, the way it’s affecting you, and how to use the right tools to get you moving forward. David is an NBA Mindset Coach (and former professional basketball player himself), a Top 50 worldwide motivational speaker, and an author. He’s been teaching professional athletes and Fortune 100 executives how to develop unshakeable mindsets for the past 15 years. “The traditional belief that hard work is the only way to succeed is flawed,” David says. In his newest book, “ Do It: The Life-Changing Power of Taking Action ,” he gives you other options to explore and tells you why they work with an unconventional approach: “The heart is your armor. The brain is your sword. Together, working as one unit, this is what makes you a warrior: the brain and heart connection.” Today’s conversation gets into how you can defeat fear and take action by using a no-fail formula to eliminate hesitation. This requires repetition (your daily habits) plus instinct (your gut feelings) plus trust (belief in the process). You’ll also get tools that will help you unlock your personal roadblocks and achieve your goals. Watch this episode on YouTube ! Find all the links and resources in the show notes . WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Customized Nootropics for Your Own Neurochemistry : https://nootopia.com/dave , use code DAVE10 to get 10% off Kickstart Autophagy: https://timelinenutrition.com/DAVE , use the code ASPREY10 to get 10% off any plan See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 28, 2023

Learn how to expand your wisdom, cultivate a generous culture, invest in mentorship, and thrive in relationships as a leader. Chip Conley, MBA, talks with Dave in Austin about the concept of wisdom, transcending age boundaries, and the importance of writing down life lessons. He firmly believes that curiosity is the elixir of life. He also explores the paradigm shift in company culture, where focusing on “cultural add” rather than “cultural fit” can foster innovation and diversity. Drawing on his experience that propelled Airbnb’s success, Chip uncovers how Airbnb maintains its strong cultural focus through cultural values interviews and company-wide gatherings. A big part of mid-life includes navigating and understanding different generations, especially in the workplace. Chip earned the name “Modern Elder” in a surreptitious way through his work with much younger employees. Airbnb looked to Chip’s sustained success in the hospitality space and asked him to help transform their start-up into the world’s leading hospitality brand more than a decade ago. He came on to lead Global Hospitality and Strategy. Then 52, he was twice the age of the average Airbnb employee. This earned him the title “Airbnb's Modern Elder” who was as curious as he was wise. He’s currently the company’s Strategic Advisor for Hospitality and Leadership. That experience influenced Chip to create the Modern Elder Academy—a new roadmap for midlife and learning opportunities—at an oceanfront campus in Baja California Sur, Mexico. Chip’s also a New York Times bestselling author, an in-demand public speaker (especially TEDtalks!) and is on the advisory council for the Stanford Center on Longevity. Watch this episode on YouTube ! Find all the links and resources in the show notes . SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Learn more about Modern Elder Academy at https://www.modernelderacademy.com and use code DAVE20 to save 20% off in-person workshops, MEA Online, or Sabbatical Sessions. *Offer valid throughout 2023 (some minor restrictions may apply). SPECIAL PRESENTATION: Live Fireside Chat: Dr. Mark Hyman & Chip Conley : The universe aligned to bring Dr. Mark Hyman and Chip Conley to Austin to talk with Dave on The Human Upgrade recently. If you missed Mark’s chat with Dave about how to be “Young Forever," listen here . Then, Dr. Mark and Chip connected for a Live Fireside Chat— listen here ! WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Great Sleep & Refreshed Mornings: https://neurohacker.com/asprey , use code DAVE to get an extra 15% off 9th Annual Biohacking Conference: https://biohackingconference.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 25, 2023

Learn the Top 10 hallmarks of aging, the role of functional medicine in restoring and reversing aging, and the many practical ways you can promote your own longevity. Mark Hyman, M.D., joins Dave in Austin to talk all things longevity. Driven by his desire for a healthier, longer life for himself and others, Dr. Mark immersed himself in the latest scientific research on aging and longevity. Through his findings, he realized that the body has an incredible built-in healing system that can be activated through understanding the emerging science of longevity. He also managed to reduce his biological age by 20 years effectively. He consistently tackles the topic of inflammation and its impact on aging—or “Inflammaging” as he calls it. “The body only has so many ways to say ouch,” Dr. Mark says. “You have pain. You have inflammation. You have certain things that happen that create all these symptoms, but there're these common roots. So, inflammation is this common root that seems to accelerate as we get older. So, we can measure biomarkers of inflammation that are highly predictive of mortality.” This conversation covers many components of aging, like metabolic flexibility and resilience, mTor, meat- and plant-based protein, nutrition, environmental allergies and food sensitivities, histamine, autophagy, fasting, DEXA scans, and much more! In his newest book, " Young Forever: The Secrets to Living Your Longest, Healthiest Life ,” Dr. Mark: shares the knowledge of how to unlock the causes of accelerated aging and treat it as a reversible disease. gives you practical tips for daily habits that will increase your energy and performance. teaches you why you age and what it really takes to live a longer, more vibrant life. Watch this episode on YouTube ! Get all the links and resources in the show notes . WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Sleep Solutions for High Performance: https://sleepbreakthrough.com/dave , use code DAVE10 to get an extra 10% off Join us at the 9th Annual Biohacking Conference: https://biohackingconference.com Dave Asprey’s NEW Book! “Smarter Not Harder: The Biohacker’s Guide to Getting the Body and Mind You Want" https://daveasprey.com/books/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 20, 2023

Here's what you must know about the health risks and extensive symptoms of breast implant illness, as well as removal solutions. Dr. Robert Whitfield MD discusses the often-overlooked health risks associated with breast implants. Women who experience breast implant illness have symptoms like brain fog, memory loss, fatigue, joint pain, anxiety, and many more. While there’s not a definitive cause of breast implant illness, a common theory points to an immune system response. Breast implants in the body can lead to persistent foreign body reactions, silicone toxicity, heavy metal exposure, biofilm development around the implants, and free radical/oxidative damage. Over time, these reactions weaken the immune system and cause health symptoms from minor to severe. Your autoimmune response, endocrine system, thyroid & adrenals, and gut all could be affected. Dr. Robert Whitfield MD’s an Austin-based plastic surgeon who’s cared for hundreds of women with breast implant illness, performs breast explants, and teaches other surgeons about this illness and treatment methods. In his years of experience in breast reconstruction for cancer patients, microsurgery, and a deep understanding of the body's reactions to foreign materials, he's developed a unique insight into the world of breast implant illness. This episode serves as a guide to what could be happening in your body, what symptoms to watch for, and breast implant removal options if you suspect you may have breast implant illness. Get more information and take a quiz at https://breastimplantillnessexpert.com and share this important episode with your spouse, a family member, a friend, or a colleague. Watch this episode on YouTube ! Find all the links and resources in the show notes . WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Must-Have Magnesium: https://magbreakthrough.com/dave , use code DAVE10 to get a 10% discount Feel Dangerously Good! Discover the energy, focus and performance that come from mineralized coffee designed with your biology in mind. Your cells will thank you. dangercoffee.com , use code DAVE15 to save 15% Vitamin DAKE & Minerals 101: Foundational vitamins and essential minerals that do the most good across every system in your body. vitamindake.com , use code DAVE10 to save 10% See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 18, 2023

Get actionable expert tips on testing, nutrition, and lifestyle changes you can do to achieve peak adrenal function. Izabella Wentz, PharmD., aka the “Thyroid Pharmacist,” takes on adrenal fatigue, its symptoms, and the importance of fixing adrenal function in addition to treating thyroid issues in her new book, “ Adrenal Transformation Protocol: A 4-Week Plan to Release Stress Symptoms and Go from Surviving to Thriving .” She went deep into the research to develop an actionable guide for you. Her new book helps you identify and mitigate the effects of adrenal dysfunction. If you’re experiencing low energy , insomnia , brain fog , anxiety or burnout , your adrenals may be overworked. You’ll learn why adrenal, immune, and thyroid issues develop as an adaptive mechanism to protect you in times of danger. You’ll also learn how to manage four big stressors that influence your adrenals in a negative way. You’ll find out what lifestyle and mindset changes you can make that turn off danger signals and communicate safety messages to your body. Her protocol emphasizes providing the body with more safety signals to counteract the stress response. She recommends dietary changes, anabolic-focused exercises, and supplements such as carnitine. She also explains the role of adrenal dysfunction in allergies and histamine issues, the dangers of B6 supplements, and the importance of balancing sodium and potassium intake for adrenal health. She suggests Epsom salt baths, a cold bedroom, and paying attention to factors such as H. Pylori, malabsorption, and the CBS gene mutation to address ammonia levels in the body. If you suspect your adrenals are on the fritz, Izabella stresses the importance of a varied and holistic approach to treatment. She urges proper testing and diagnosis of adrenal dysfunction and thyroid issues to build resilience in your body. Watch this episode on YouTube ! Find all the links and resources in the show notes . WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Micronutrients Boost HRV: https://modemethod.com , use code DAVE to get 15% off your first order Feel Dangerously Good! Discover the energy, focus and performance that come from mineralized coffee designed with your biology in mind. Your cells will thank you. Go to dangercoffee.com , use code DAVE15 to save 15% Vitamin DAKE & Minerals 101: Foundational vitamins and essential minerals that do the most good across every system in your body. Go to vitamindake.com , use code DAVE10 to save 10% See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 14, 2023

Learn about nitric oxide’s crucial role in your body systems, how to naturally produce more of it, and how to supplement effectively and safely. Research scientist Nathan Bryan, Ph.D., has been involved in nitric oxide research for the past 25 years and has made many discoveries in the field. He’s an international leader in molecular medicine and nitric oxide biochemistry. You'll find out how nitric oxide works within major body functions and what you can do to increase your body's natural production of it. Pneuma Nitric Oxide sponsored this episode. Human performance depends on sufficient oxygen and nutrient delivery to organs, tissues, and cells so they can do their job. Nitric oxide controls oxygen and nutrient delivery. It’s now recognized “as one of the most important molecules produced in the body of humans,” Nathan says. “It's a vasodilator, so it controls the regulation of blood flow. It's what's responsible for oxygen and nutrient delivery to every organ, tissue, and cell in the body.” That’s why it’s so important to find the right carrier to effectively deliver this complex and bioactive gas that’s gone in less than a second. Nathan was one of the first scientists to develop a technology to make a solid dose form of nitric oxide. He shares information about Pneuma Nitric Oxide’s key products, like its lozenges, and the N1O1 skincare line . The lozenges open small blood vessels internally and the topicals open superficial blood vessels on the skin to improve blood flow and cellular turnover. He explains how to use a nitric oxide-generating serum on your skin from his N1O1 skincare line that enhances blood flow and promotes wound healing. Nathan presents the anti-aging, performance-enhancing, and nootropic benefits of nitric oxide along with its role in improving stem cell function, controlling telomerase activity, and improving mitochondrial function. He identifies the different isoforms of nitric oxide for you, noting that you should choose a nitric oxide supplement that delivers the same amount of nitric oxide that the body would normally produce. He emphasizes the importance of restoring the body's ability to naturally produce nitric oxide and debunks the use of nitric oxide precursors such as L-arginine and citrulline. He also stresses using safe and effective nitric oxide products. SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://n1o1.com and use code DAVE to get 10% off and free shipping . Watch this episode on YouTube ! Find all the links and resources in the show notes . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 13, 2023

IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... a legacy upgrade conversation with Ingrid Fetell Lee gets into the topic of joy and the influence of your surroundings on your emotions and well-being. You may be hacking your body and mind, but are you embracing joy along the way? This episode shows you how—and explains why it’s essential. You’ll also find out the difference between happiness vs. joy. Fun Fact: While you may be able to fake a smile, you can’t fake joy. Ingrid brought joy into the popular culture conversation with her book, “ Joyful: The Surprising Power of Ordinary Things to Create Extraordinary Happiness .” She’s a designer, author, TEDtalk speaker and founder of “ The Aesthetics of Joy .” Her work empowers people to find more joy through the purposeful and emotion-driven design of their environments. She’s identified 10 elements of joy that resonate with nearly everyone. Energy Abundance Freedom Harmony Play Surprise Transcendence Magic Celebration Renewal Ingrid explains how to recognize, feel and incorporate more joy into your everyday life. FREE JOY RESOURCES: Downloadable guides: 50 Ways to Find Joy Every Day and Joyspotter’s Guide WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Electrolytes That Taste Good With Zero Sugar Hydration: https://drinklmnt.com//dave , get a FREE LMNT Sample Pack Get Your Tickets! 9th Annual Biohacking Conference: https://biohackingconference.com Dave Asprey’s NEW Book! “Smarter Not Harder: The Biohacker’s Guide to Getting the Body and Mind You Want” is out now. https://daveasprey.com/books/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 11, 2023

IN THIS EPISODE OF THE HUMAN UPGRADE™… former rocket scientist and former law professor Ozan Varol—an expert in creativity, innovation, and critical thinking—says that unlocking your full potential involves reimagining the status quo rather than simply resisting it. “The word resist for me gets in the way because often resistance becomes a different way of conformity, as in you're resisting something but you're not really offering a new path forward,” he says. “So, resistance becomes its own end in and of itself. The goal should be re-imagination.” In this discussion about Ozan’s newest book, “ AWAKEN YOUR GENIUS: Escape Conformity, Ignite Creativity, and Become Extraordinary ,” you’ll learn to access the best parts of your brain and create your own path as a leader and creator by acting instead of reacting. While people consider those who blaze their own trail as geniuses, Ozan contends that genius is not limited to a select few. Rather, it can be discovered by anyone. He loaded this book with smart tips, examples, things to think about, and things to do. For example, you’ll learn why you should ignore email until noon and spend the most valuable time of your day thinking in creativity. You’ll also learn how spending more time on the “why” than the “what” moves you toward the life you really want to be living. He lays out an action roadmap for you to cultivate your own genius and be in charge of your time and creativity. Watch this episode on YouTube ! Find all the links and resources in the show notes . WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Sleep Solutions for High Performance: https://sleepbreakthrough.com/dave , use code DAVE10 to get an extra 10% off Feel Dangerously Good! Discover the energy, focus and performance that come from mineralized coffee designed with your biology in mind. Your cells will thank you. https://dangercoffee.com , use code DAVE15 to save 15% Vitamin DAKE & Minerals 101: Foundational vitamins and essential minerals that do the most good across every system in your body. vitamindake.com , use code DAVE10 to save 10% See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 7, 2023

In this Episode of The Human Upgrade™...​ Dave talks to David Hinds of Brisbane, Australia, about gut issues and weight loss for men at mid-life. David’s already biohacking, working out, and taking supplements he thinks are the right ones—yet the weight around his mid-section persists. This intervention looks at ways to tackle hard-to-budge love handles and extra mid-section weight with suggestions covering hormones, thyroid, sleep, SIBO, probiotics, supplements, inflammation, the pituitary gland, prolactin, and potassium. This discussion gets into libido and eyesight, too. David’s in his early 50s and a dad to two teenagers. He started biohacking over three years ago when he discovered the Bulletproof Radio podcast (now called The Human Upgrade). He then read Dave’s books , made some life changes, saw the results, and decided 150 years on this rock would be awesome! “So, I'm one-third of the way through life, and my aim is to be in the best physical and mental state possible for all of those years,” he says. Note: The "Interventions With Dave” recommendations are designed to help you upgrade yourself and your biology so you can perform better at everything you do. They are not, however, a substitute for advice or treatment by a trained medical professional that may be needed for specific health conditions, illness or injury. Find a full list of the Interventions With Dave episodes here . Listen to this episode on YouTube ! WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Protein Bars with All the Good Stuff and None of the Crap: https://rowdybars.com , use code DAVE to get 10% off Kickstart Autophagy: https://timelinenutrition.com/DAVE , use the code ASPREY10 to get 10% off any plan Nature’s Nootropic: https://trukava.com , use code DAVE15 to get 15% off See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 4, 2023

IN THIS EPISODE OF THE HUMAN UPGRADE™… Vincent Pedre, M.D., explains how consuming too much sugar can lead to insulin resistance and diabetes by causing shifts in the microbiome that reduce insulin signaling. He also highlights how omega-6 fats found in processed foods contribute to inflammation and chronic disease by carrying lipopolysaccharide toxins through cell membranes. For over a decade, board-certified internist and Functional Medicine certified practitioner, Dr. Pedre, founder of Happy Gut Life , has helped people improve their well-being and quality of life by building the foundation of gut health that supports total physical and mental wellness. He believes that healing begins in the kitchen through the foods we eat. He brings together years of research and clinical experience to offer you real solutions in his newest book, “ The GutSMART Protocol: Revitalize Your Health, Boost Your Energy, and Lose Weight in Just 14 Days with Your Personalized Gut-Healing Plan .” The balance between good and bad bacteria is both important and nuanced—more microbial diversity in the gut is not always better. "The focus should be on metabolomics, not just diversity when it comes to gut bacteria,” Dr. Pedre says. Another focus includes gut interrelationships and the seven big systems in your body affected by leaky gut: skin, airway, brain, joints, energy, metabolism, and immune system. Watch this episode on YouTube ! Find all the links and resources in the show notes . WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Anti-aging Powerhouse : https://spermidinelife.us/dave , use code DAVE25 to save 25% on your first purchase Must-Have Magnesium: https://magbreakthrough.com/dave , use code DAVE10 to get a 10% discount Dave Asprey’s NEW Book! “Smarter Not Harder: The Biohacker’s Guide to Getting the Body and Mind You Want” is out now. https://daveasprey.com/books/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 30, 2023

IN THIS EPISODE OF THE HUMAN UPGRADE™… An air quality expert explains the impact of your home environment on your health, mold sensitivities, and the remediation process, including DIY tips and professional interventions. You’ll also find out about The Dust Test , which identifies mold, bacteria, and biotoxins in your home so the inspector can remove all sources of contamination. Mold is likely a problem in your home, as it is for many people, and you likely don’t know what to do about it. Every year, mold damages property and costs homeowners money. But worse than that, mold is dangerous to your health, especially if you are one of 375 million Americans who are susceptible to chronic mold sensitivity. With decades of field experience, Michael Rubino, president of HomeCleanse , excels at working with individuals—many of whom are who are immunocompromised—to detoxify their homes and improve indoor air quality. He has helped more than 1,000 families heal from toxic mold exposure so far, and, as he says, this is just the beginning. Through scientific expertise and innovation, Michael developed alternative remediation protocols that eliminate common mold sources and eradicate the contamination caused by those sources. His expert advice in this episode is a go-to resource for anyone worried about an increasingly common problem that can have life-threatening side effects. And his book The Mold Medic can definitely help you breathe easier. SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to www.thedusttest.com/dave and use code DAVE to get $10 off . Watch this episode on YouTube ! Links and resources can be found in the show notes . WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Sleep Solutions for High Performance: https://sleepbreakthrough.com/dave , use code DAVE10 to get an extra 10% off Get Your Tickets! 9th Annual Biohacking Conference: https://biohackingconference.com Dave Asprey’s NEW Book! “Smarter Not Harder: The Biohacker’s Guide to Getting the Body and Mind You Want.” https://daveasprey.com/books See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 29, 2023

IN THIS EPISODE OF THE HUMAN UPGRADE™… you’ll learn how Functional Medicine expert Jill Carnahan, M.D., who is board certified in Family Medicine and Integrative Holistic Medicine, survived breast cancer, Crohn’s disease, and toxic mold. Her unique healing approach looks to science for answers while also using methods that outright challenge conventional medicine. During the discussion, Dr. Carnahan distinguishes between visible (e.g., cancer) and invisible (e.g., mold toxicity) illnesses. “There's this new term called medical gaslighting where doctors actually say, "Oh, everything looks great," right? And you're not. You're not okay inside,” she says. Her new book, “ Unexpected: Finding Resilience through Functional Medicine, Science, and Faith ,” explores “positive transformation against all odds.” She shares her own story of confronting life-altering illnesses, fighting for her health, and overcoming sickness using both science and faith. She also shares the experiences of her patients who transformed their health and their lives. Get ready to learn about a new path of empowerment where you can take control of your own health and well-being. Watch this episode on YouTube ! Find all the links and resources in the show notes . Get Your Tickets! 9th Annual Biohacking Conference: https://biohackingconference.com Dave Asprey’s NEW Book! “Smarter Not Harder: The Biohacker’s Guide to Getting the Body and Mind You Want.” https://daveasprey.com/books/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 23, 2023

IN THIS EPISODE OF THE HUMAN UPGRADE™… you’ll learn why many professional athletes, especially fighters, are some of the top biohackers in the world. They hack their bodies, minds, and environments to achieve an incredibly high level of performance. Every hack they do has to be effective—and means the difference between winning and losing. Professional MMA (mixed martial arts) fighter Miesha Tate knows and does just that while adding being a parent and entrepreneur into the mix. Miesha is a former UFC and Strikeforce Bantamweight champion, ONE Championship vice president, and winner of Celebrity Big Brother Season 3. She always draws on her experiences, whether from home birth or competing on the world’s biggest stages as a pro athlete as proof that when the mind and body are functioning with synchronicity, you are capable of great things. After more than a decade of wrestling and MMA competition culminating in her UFC World Championship in 2016, she stepped out of the octagon. “I retired from the sport and it took five years to figure out who I am other than Miesha Tate, the fighter,” she says. “So not only did I go soul searching, but I also went wellness searching.” She found red light to help her recovery and healing, hyperbaric oxygen therapy to restore and protect her brain, and breathing techniques to keep her present and grounded. She learned, too, the importance of mindfulness and attention to self—“to just be alone with your own thoughts.” She says there’s reward and fulfillment in doing something every day that pushes you and makes you a little bit uncomfortable. No pain required. She came back to professional MMA fighting after having two children and changed up nearly everything about her training. This included moving from Bantamweight to Flyweight, which meant reducing her already lean frame by another 10 pounds. She now looks at her body and mind as a comprehensive unit: the big things like hormones, nutrition, sleep and brain health; flow state during her fights; and she even takes on the more elusive soul work. Miesha focuses on empowering women through martial arts, with a particular emphasis on self-defense and building confidence. She’s become an advocate for women in combat sports, using her platform to promote equality and opportunities for women in the sport. She also helps others heal, recover, and discover their potential at Desert Moon Wellness , which she co-founded with two women partners. She lists her three most important things in life as: 1) Family and friends, 2) time, and 3) goals and dreams. Watch this episode on YouTube ! All the links and resources are available in the show notes . WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Must-Have Magnesium: https://magbreakthrough.com/dave , use code DAVE10 to get a 10% discount Micronutrients Boost HRV: https://modemethod.com , use code DAVE to get 15% off of your first order Get your tickets to the 9th Annual Biohacking Conference: https://biohackingconference.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 21, 2023

IN THIS EPISODE OF THE HUMAN UPGRADE™… Will Cole, IFMCP, DNM, DC , teaches you how your body directly affects your mood. Hint: the gut plays a role, but there are other factors too. Through treating thousands of patients, Dr. Cole developed new ideas involving both psychology and biology that you can use in your daily life. He’s an expert in finding the underlying factors of chronic disease and challenges the labeling of “fitness” as a masculine industry and “wellness” as a feminine industry. His newest book, “ Gut Feelings: Healing the Shame-Fueled Relationship Between What You Eat and How You Feel ,” encourages you to be aware of the link between what you eat and how it makes you feel. Dr. Cole explains the connection between physical and emotional health and introduces you to the term “shameflammation.” It's how stress and shame can cause gut inflammation and sabotage your health. Additionally, problems with your gut often show up as mood swings, anxiety, and food cravings. He offers a framework to better understand your gut-brain connection and solutions to help you heal. “Gut Feelings” gives you 50 healing recipes; dietary prescriptions founded on flexibility and awareness; and mindfulness techniques to strengthen your intuition and discover your priorities. Watch this episode on YouTube ! Find all the links and resources in the show notes . WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Experience the Benefits of Infrared Sauna: https://www.sunlighten.com , use code DAVE to save up to $600 Get your tickets to the 9th Annual Biohacking Conference: https://biohackingconference.com Dave Asprey’s NEW Book! “Smarter Not Harder: The Biohacker’s Guide to Getting the Body and Mind You Want” is out now. https://daveasprey.com/books/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 16, 2023

IN THIS EPISODE OF THE HUMAN UPGRADE™… Daniel Amen, M.D., shares the most effective daily habits you can do to improve the way your brain works, based on his 40 years of clinical practice. In this discussion and in his new book, “ Change Your Brain Every Day: Simple Daily Practices to Strengthen Your Mind, Memory, Moods, Focus, Energy, Habits, and Relationships ,” he delivers a year’s worth of habits to you in short info bits and daily actions. Incorporating Dr. Amen’s tiny habits and practices will help you: · Manage your mind to support your happiness, inner peace, and success · Develop lifelong strategies for dealing with whatever stresses come your way · Create an ongoing sense of purpose in a way that informs your daily actions · Learn major life lessons Dr. Amen has gleaned from studying hundreds of thousands of brain scans A key innovator in the world of brain health, Dr. Amen shifts the paradigm of understanding what's happening in your brain. His new book is a must-have for anyone who values both their brain function and mental health. He teaches you how your gut affects your thinking, how mental health is really brain health, and how measuring brain function is tied to mitochondrial function. A psychiatrist and clinical neuroscientist, Dr. Amen has collected the world’s largest database of brain scans for psychiatry. This totals more than 210,000 SPECT scans on patients from 155 countries. This has been key to going beyond what he learned as a psychiatrist. Actually observing “the organ” in question has been a game changer for his mission to end mental illness by creating a revolution in brain health. Watch this episode on YouTube ! Get all the links and resources in the show notes . WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Sleep Solutions for High Performance: https://sleepbreakthrough.com/dave , use code DAVE10 to get an extra 10% off Capture Life Force Energy: https://leelaq.com , use discount code DAVE10 to get 10% off sitewide Comfort Options for Hot & Cold Sleepers : https://sleep.me/daveasprey , use code ASPREY for 25% off See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 14, 2023

IN THIS EPISODE OF THE HUMAN UPGRADE™… you’ll learn how much control you can actually have over your brain. There’s a new way of accessing your meat operating system that adds an important element that’s been missing from the brain training conversation. Moha Bensofia joins the show to explain a new piece of neurotech called Mendi . He shares the benefits of getting more blood to the front of your brain. Mendi uses neurofeedback to provide visual feedback based on your brain activity. A headset measures the activity while you play a fun brain-training mobile game. The system uses fNIRS technology to measure blood flow and oxygenation in the pre-frontal cortex of the brain. The brain training game requires focus and calmness, which increases activity and control of your brain’s pathways. By using Mendi, you can learn to control your brain activity and reach greater heights as an entrepreneur, athlete, and professional in any field. Mendi was developed initially for victims of war and trauma, as well as people struggling with anxiety, PTSD, and ADHD. But, as you’ll learn, everyone can benefit from this type of brain training. SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://www.mendi.io and use code DAVE to save 15% . Watch this episode on YouTube ! WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Liquid Ketones for Better Energy, Focus & Endurance : https://hvmn.com , use code DAVE to get 20% off Join us at the 9th Annual Biohacking Conference: https://biohackingconference.com Dave Asprey’s NEW Book! “Smarter Not Harder: The Biohacker’s Guide to Getting the Body and Mind You Want” is out now. https://daveasprey.com/books/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 10, 2023

IN THIS EPISODE OF THE HUMAN UPGRADE™… you’ll learn Luke Storey ’s definition of addiction and his strategies for healing, happiness, and high performance. He’s known for his irreverent, passionate, and humorous delivery, and it shows through in this conversation. He overcame tremendous adversity from childhood trauma, adolescent criminality, and years of chronic alcohol and drug addiction. For 25 years, he’s focused on recovery, inner work, and personal development. If you’re currently working on addiction recovery, you’ll learn a lot from his experience. And even if you don’t share any aspect of Luke’s dark background, you may have your own type of addiction that could benefit from his wisdom. Luke’s a great writer, meditation and metaphysics teacher and lifestyle design expert who shares with you his transformative principles of health, addiction recovery, and spirituality. This discussion dives deep into addiction, how psychedelics—properly used with the help of a professional—can aid your recovery, and what it really takes to live and thrive once you get sober. Watch this episode on YouTube ! SPECIAL ANNOUNCEMENT FOR THE HUMAN UPGRADE LISTENERS: Protect yourself, your home, and your family from the dangers of EMF and 5G with Luke Storey’s EMF Home Safety Masterclass. Find the class at online.lukestorey.com WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Must-Have Magnesium: https://magbreakthrough.com/dave , use code DAVE10 to get a 10% discount A Probiotic to Ease Stress: https://www.omnibioticlife.com/DAVE , use code DAVE20 to get 20% off Dave Asprey’s NEW Book! “Smarter Not Harder: The Biohacker’s Guide to Getting the Body and Mind You Want” is out now. https://daveasprey.com/books/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 8, 2023

IN THIS EPISODE OF THE HUMAN UPGRADE™… Amy Shah, M.D., teaches you all you need to know about the second F word: food. That’s right, you are going to learn all about hunger from the author of the book, “ I'm So Effing Hungry: Why We Crave What We Crave – and What to Do About It .” You’ll also find out why focusing on your hunger is more important and effective than going on yet another diet. Dr. Shah is a double board-certified medical doctor and nutrition expert with training from Cornell, Columbia, and Harvard universities. Her background includes internal medicine and allergy/immunology. During this discussion, she shares why she believes that you can diet all you want, but diets don't work—and, worse yet, they keep you addicted. They also keep you hungry and keep you unhappy. She helps you lean into your body signals and really understand what's happening. She developed a 5-step program for battling excessive hunger and food cravings by harnessing the power of psychobiotics and intermittent fasting. She combined scientific studies with Western and Ayurvedic approaches so you can: REPLENISH your body by eating more nourishing, mood-balancing foods. REWIRE your brain to undo the addiction pathways and cravings for processed foods. RESET your circadian rhythm to activate hunger hormones that reduce your appetite. REFRESH with a good night’s sleep, using proven good sleep habits used by the U.S. military. RETRAIN your body with exercise that regulates key neurotransmitters that influence our hunger response. You’ll want to take notes on this extremely helpful and actionable interview. You also can download the transcript in the episode show notes under "Links & Resources." Watch this episode on YouTube ! WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Nature’s Nootropic: https://trukava.com , use code DAVE15 to get 15% off Kickstart Autophagy: https://timelinenutrition.com/DAVE , use code ASPREY10 to get 10% off any plan Join us at the 9th Annual Biohacking Conference: https://biohackingconference.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 3, 2023

Mute sponsored this episode. In this "Upgrade Spotlight" Episode of The Human Upgrade™... you’re getting the latest knowledge about innovative biohacking tools and technologies that allow you to change your biology and the environment around you. CEO Michael Johnson joins the show from the Rhinomed headquarters near Melbourne, Australia. Rhinomed, the company behind Mute , pioneers the use of adjustable nasal devices for respiration, sleep, nasal diagnostics, and nasal drug delivery. You’re going to learn about a Mute nasal device that will help you get a much better night's sleep. Think of it as the first line of defense against snoring and sleep disruption. It’s a small device made of soft, adjustable polymers that sits comfortably inside your nose, increasing airflow and improving breathing. Watch this episode on YouTube ! SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to MUTESNORING.COM and use code DAVE10 for 10% off and free shipping in the US, Canada, and Australia WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Dave Asprey’s NEW Book! “Smarter Not Harder: The Biohacker’s Guide to Getting the Body and Mind You Want” is out now! IndieBound / Barnes & Noble / Apple Books / Amazon 9th Annual Biohacking Conference: https://biohackingconference.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 2, 2023

IN THIS EPISODE OF THE HUMAN UPGRADE™... a look into the story of the human mind wonders if you’re just a machine made of meat. Guest Paul Bloom, a researcher, teacher and author, studies adult and child development in terms of how people make sense of the world. It turns out that there are all kinds of automated systems in your body that are making sense of the world for you and after they do that, they give you a picture of the world. The interesting part is that picture may be more or less accurate based on a lot of things that are part of your programming. Paul is a professor of Psychology at the University of Toronto and professor emeritus of Psychology at Yale University. He teaches a popular “Intro to Psychology” class that he turned into his seventh book, called: “ Psych: The Story of the Human Mind .” Because he studies psychology at so many different levels, he brings new knowledge and new synthesis of ideas to the discussion of the human mind. Topics range from consciousness to ChatGPT and BDSM, from whether you have a soul or if you can attain happiness. Paul’s writing and lectures show how psychology can give us practical insights into important issues. He addresses the treatment of mental illnesses such as depression and anxiety and the best way to lead a fulfilling life. This episode and his new book guide you through the most important topic there is: the story of you and your mind. Watch this episode on YouTube ! WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Sleep Solutions for High Performance : https://sleepbreakthrough.com/dave , use code DAVE10 to get an extra 10% off Comfort Options for Hot & Cold Sleepers : https://sleep.me/daveasprey , use code ASPREY for 25% off Kickstart Autophagy : https://timelinenutrition.com/DAVE , use the code ASPREY10 to get 10% off any plan See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Feb 28, 2023

IN THIS EPISODE OF THE HUMAN UPGRADE™... you will learn about the beliefs that kick in as normal humans age and most importantly, you will learn what you can do about those limiting beliefs. And who better to discuss this than the author of the book, " Gnar Country: Growing Old, Staying Rad ," Steven Kotler. Steven is a friend of the show, executive director of the Flow Research Collective, a New York Times bestselling author, and an award-winning journalist. He tested his knowledge and theories on himself in a quest to learn how to park ski (an extreme type of skiing) at age 53. Science shows that older humans are better at learning certain skills than younger people. Brain changes occur in the second half of your life that unlock levels of intelligence, wisdom, creativity, and empathy you didn’t know were possible. In the conversation, Steven describes how his book chronicles his experience pushing his own aging body past preconceived limits. He also explains why he wrote a book about goals, grit and progression - and why he feels it's an important lesson for everyone to learn (not just those of you over 50). Steven also explains why he chose extreme skiing as his No. 1 anti-aging activity. “... if you really want to preserve cognitive function, you want to basically use the hippocampus in the way that evolution designed it. You want novel, challenging experiences in outdoor environments.” Watch this episode on Youtube Find all the links and resources in the show notes . *** WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Join us at the 9th Annual Biohacking Conference: https://biohackingconference.com Dave Asprey’s NEW Book! “Smarter Not Harder: The Biohacker’s Guide to Getting the Body and Mind You Want” launches Feb. 28, 2023. IndieBound / Barnes & Noble / Apple Books / Amazon See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Feb 24, 2023

IN THIS EPISODE OF THE HUMAN UPGRADE™… the guest is one of the founders of Wired Magazine and someone who has been a continuous source of interest, news and data for decades, Jane Metcalfe. Having basically dissected nerds for her entire life, Jane now runs a fantastic newsletter and news site called NEO.LIFE where she writes about biohacking and the future. If you were to combine someone who really understands society and understands tech (and has read as much science fiction as possible) you would have Jane. Jane’s, focus throughout her, career has been on how technology is transforming our world. But now she is fascinated with how deeply we can see inside the body and how processing the data we collect allows us to discover new cells, understand complex biological systems, and engineer bacteria, viruses, DNA, and ultimately ourselves. Her new platform, NEO.LIFE is for exploring how we Homo sapiens will use these technologies and new understandings to power our own evolution. Watch this episode on YouTube ! Get all the links and resources in the show notes . WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Get the week’s news and fresh ideas from the neobiological frontier. https://neo.life Join us at the 9th Annual Biohacking Conference: https://biohackingconference.com Dave Asprey’s NEW Book! “Smarter Not Harder: The Biohacker’s Guide to Getting the Body and Mind You Want” launches Feb. 28, 2023. Pre-order yours today: IndieBound / Barnes & Noble / Apple Books / Amazon See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Feb 23, 2023

IN THIS EPISODE OF THE HUMAN UPGRADE™... to celebrate the imminent release of the new book, we’re doing something different than what you're used to. Dave is getting interviewed on his own podcast to give you a preview of his book, Smarter Not Harder . In the interviewer's seat is retired Navy SEAL commander, author, expert in leadership and human performance, Rich Diviney. When Rich was a guest on the show previously (check out episode #937 ), he talked about mindset, optimism, resilience, and stress. This time, the script gets flipped. This interview intends to educate and inform about the new book and install some new capabilities in your operating systems. The goal is that even if you don't read the book, you will still walk away from this interview with a brain that works better. Smarter Not Harder: The Biohacker's Guide to Getting the Body and Mind You Want is about helping you to become the best version of yourself by embracing laziness while increasing your energy and optimizing your biology. Rich is the perfect person to dive deeply into how the big ideas in this book work and give you an even greater reason to get the mind and body you want. Dave packed “Smarter Not Harder” with practical, accessible information based on the latest research so you can achieve lasting health in less time. It’s biohacking fully applied. You can pick up a copy of Smarter Not Harder: The Biohacker's Guide to Getting the Body and Mind You Want at your favorite place to buy books. Watch this episode on YouTube ! Get all the links and resources in the show notes . WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Sleep Solutions for High Performance : https://sleepbreakthrough.com/dave , use code DAVE10 to get an extra 10% off Dave Asprey’s NEW Book! “Smarter Not Harder: The Biohacker's Guide to Getting the Body and Mind You Want” launches Feb. 28, 2023. Pre-order yours today: IndieBound / Barnes & Noble / Apple Books / Amazon 9th Annual Biohacking Conference: https://biohackingconference.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Feb 21, 2023

IN THIS EPISODE OF THE HUMAN UPGRADE™... Dave talks with Cindy Fraley, who has a young daughter, works in upper-level management at a large pharmaceutical company, and is a former physical therapist who overcame RA, MRSA, Hashimoto’s and emotional stress. Cindy says, “Dave’s guidance, the Upgraded Collective, and biohacking have been pivotal in my journey back to the great health, sports, and outdoor activities that I previously had and love.” In fact, in the past year, Cindy has improved her Blood work significantly using EDTA chelation suppositories, sauna, and IV therapy to deal with mold, metals, and coronary calcification. She’s done a deep dive into meditation and forgiveness and has incorporated HeartMath into her day. Cindy is also proudly managing her work stress better so it doesn’t impact her sleep or family interactions. During this intervention and episode, Cindy would like Dave’s help to continue working on stress reduction/management and focus on her brain and neurological fitness. Find all the links and resources in the show notes . Watch this episode on YouTube . WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Shield Yourself from EMFs: https://quantumupgrade.io , use code DAVE to get a two-week free trial Dave Asprey’s NEW Book! “Smarter Not Harder: The Biohacker's Guide to Getting the Body and Mind You Want” launches Feb. 28, 2023. Pre-order yours today: IndieBound / Barnes & Noble / Apple Books / Amazon 9th Annual Biohacking Conference: https://biohackingconference.com Note: The “Interventions With Dave” recommendations are designed to help you upgrade yourself and your biology so you can perform better at everything you do. They are not, however, a substitute for advice or treatment by a trained medical professional that may be needed for specific health conditions, illness or injury. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Feb 16, 2023

IN THIS EPISODE OF THE HUMAN UPGRADE™... Dave talks with Bryan Gardner (a self proclaimed “super-dad”) who wants to take his current hacking to the next level. Bryan has questions specifically about his brain & neurology, his fitness, and spirituality. Bryan is an aerospace engineer who built a small hedge fund business more than a decade ago. So he doesn’t sound like someone who would be struggling with productivity, focus and managing his energy. This episode covers many meaningful and helpful topics, including blood flow restriction, high intensity intervals, neuromuscular electrical stimulation, neurofeedback, and a whole lot more. Watch this episode on YouTube ! Get all the resources and links in the show notes . ------ WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Customized Nootropics for Your Own Neurochemistry : https://nootopia.com/dave , use code DAVE10 to get 10% off Humic & fulvic minerals provide critical cellular support. Go to https://www.beamminerals.com and use code DAVE20 to get 20% off . 9th Annual Biohacking Conference: https://biohackingconference.com ------- Note: The “Interventions With Dave” recommendations are designed to help you upgrade yourself and your biology so you can perform better at everything you do. They are not, however, a substitute for advice or treatment by a trained medical professional that may be needed for specific health conditions, illness or injury. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Feb 14, 2023

IN THIS EPISODE OF THE HUMAN UPGRADE™... Dave talks with Mandy Pennington, a longtime Upgrade Collective member and dedicated hacker who has used biohacking techniques successfully to upgrade her body and mind. Mandy is a sharp and curious person who wants to learn more about how to apply the topics in Smarter Not Harder to her spirituality, quantum energy, spirit guides, and leading a purpose-driven life that feels right for her soul. An important aspect of this episode is focussed on how Mandy can refine her current spirituality practices, and increase her spiritual resilience to align with the next steps on her biohacking journey. Which is something that will likely resonate with you. Watch this episode on YouTube ! Note: The “Interventions With Dave” recommendations are designed to help you upgrade yourself and your biology so you can perform better at everything you do. They are not, however, a substitute for advice or treatment by a trained medical professional that may be needed for specific health conditions, illness or injury. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Dave Asprey’s NEW Book ! “Smarter Not Harder: The Biohacker's Guide to Getting the Body and Mind You Want” launches Feb. 28, 2023. Pre-order yours today: IndieBound / Barnes & Noble / Apple Books / Amazon Knowing Labs : Test Your Own Biology: https://knowinglabs.com/dave , use code dave to save 20% off any test kit Capture Life Force Energy: https://leelaq.com , use discount code DAVE10 to get 10% off sitewide See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Feb 9, 2023

IN THIS EPISODE OF THE HUMAN UPGRADE™... I am honored and grateful to bring you a conversation that I recorded in person with Gurudev Sri Sri Ravi Shankar at the Art of Living Center in Los Angeles. Gurudev Sri Sri Ravi Shankar is a leader of an international movement with more than 50 million followers who do breathwork every single morning. He has worked for 40 years as a global ambassador for peace at the highest levels. I did his breathwork exercises every morning without fail for five years while fixing my mind, body and nervous system, and I have a huge amount of respect for his work in the world. It was a joy to chat with him in person and his childlike curiosity, enthusiasm for teaching, and deep understanding of the world are echoed in every word of this episode. Gurudev is a true visionary, so I am grateful that he set aside time to talk with me so I could share his wisdom with you. Watch this episode on YouTube ! WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Sleep Solutions for High Performance : https://sleepbreakthrough.com/dave , use code DAVE10 to get an extra 10% off Comfort Options for Hot & Cold Sleepers : https://sleep.me/daveasprey , use code ASPREY for 25% off your purchase Dave Asprey’s NEW Book! “Smarter Not Harder: The Biohacker’s Guide to Getting the Body and Mind You Want” launches Feb. 28, 2023. Pre-order yours today: IndieBound / Barnes & Noble / Apple Books / Amazon See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Feb 7, 2023

IN THIS EPISODE OF THE HUMAN UPGRADE™... I do something different. Over the past 1000+ episodes, I have spent a lot of time talking and learning from my guests, but I have heard over and over that you would like to hear more from me about what I am doing, trying and thinking. Well, that can be awkward to do sitting alone in front of a microphone. A while ago, Danica Patrick interviewed me and it is one of my favorite podcast interviews ever. Danica did a great job of digging into why I do what I do, why I think the way I think, and best of all she allowed me to talk about parts of my life that I have never talked about anywhere else. So, Danica has kindly allowed me to drop that episode from her podcast, Pretty Intense, right here on the Human Upgrade. You are going to learn a lot from the episode. We hit on a lot of pretty next-level stuff - our conversation even allowed me to dig into the concept of old souls (or reincarnation), and how that affects our current life. Danica is a fascinating person and an excellent interviewer. You are going to enjoy this feed drop. Watch this episode on YouTube ! WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Kickstart Autophagy: https://timelinenutrition.com/DAVE , use the code ASPREY10 to get 10% off any plan Nature’s Nootropic: https://trukava.com , use code DAVE15 to get 15% off Dave Asprey’s NEW Book! “Smarter Not Harder: The Biohacker's Guide to Getting the Body and Mind You Want” launches Feb. 28, 2023. Pre-order yours today: IndieBound / Barnes & Noble / Apple Books / Amazon See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Feb 4, 2023

H.V.M.N. sponsored this episode. IN THIS “UPGRADE SPOTLIGHT” EPISODE OF THE HUMAN UPGRADE ™…Metabolic biochemist Latt Mansor, Ph.D., joins the show from H.V.M.N . (Health Via Modern Nutrition), where he leads research for the company. He’s an expert in metabolism who consults with elite sport, military, clinical and research organizations. As a key biomarker of metabolic health, ketones are a source of fuel for your brain and body. They’re different from glucose and fat—and more efficient. Learning about the different kinds of ketones and how they work can help you both understand and harness their power. This discussion explains exogenous ketones, BDO-specific ketones BHB and ketone esters. You’ll also find out how to measure your ketones and why it’s important. Ketones have been shown to be anti-inflammatory. Another benefit happens during exercise. The increase in your ketone levels directly increases BDNF (brain-derived nootropic factor). When you raise ketones, you have a more flexible brain. Latt gets into the research behind H.V.M.N.’s development of drinkable ketones to improve performance. Ketone-IQ™ give you advantages like: Mental clarity and cognitive benefits Oxygen efficiency Sustained energy Performance, endurance and recovery Weight management and improved metabolic health SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://hvmn.com/DAVE , use code Dave to get 20% off. Watch this episode on YouTube ! NEW IN 2023! Dave Asprey’s NEW Book! “Smarter Not Harder: The Biohacker’s Guide to Getting the Body and Mind You Want” launches Feb. 28, 2023. Pre-order yours today: IndieBound / Barnes & Noble / Apple Books / Amazon 9th Annual Biohacking Conference: Come join like-minded people for three days of awesome biohacking, learning and connecting! June 22-24, 2023, in Orlando, Florida. https://biohackingconference.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Feb 3, 2023

IN THIS EPISODE OF THE HUMAN UPGRADE™ … Dr. Kelly Brogan shares why her views often go against conventional thinking—on topics from pharmaceuticals to sex to pole dancing to relationship compatibility. She's a psychiatrist who specializes in psychosomatic medicine and integrative holistic medicine. Her root-cause resolution approach to psychiatric syndromes and symptoms coupled with other support techniques helps women reclaim their divine feminine power. I previously talked with Dr. Kelly on episode #635 about her book, " Own Your Self: The Surprising Path Beyond Depression, Anxiety, and Fatigue to Reclaiming Your Authenticity, Vitality, and Freedom .” This romp of a discussion tackles women’s power and what it means to claim or reclaim it. And how women themselves can be harmful critics of other women’s choices. Dr. Kelly went through profound personal changes over the past few years that led to changes in her business, too. Changes that rattled some people and brought out the worst kind of social media attention. She talks about how she’s stayed firmly in her choices and offers tips for you to do the same. She also gets into why the differences in feminine and masculine power matter now more than ever. It starts with your relationship with yourself. This fun, informative interview gets a little wild and shares profound insights you can apply to your next life move. Watch this episode on YouTube ! WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! A Probiotic to Ease Stress : https://www.omnibioticlife.com/DAVE , use code DAVE20 to get 20% off Customized Nootropics for Your Own Neurochemistry : https://nootopia.com/dave , use code DAVE10 to get 10% off Dave Asprey’s NEW Book! “Smarter Not Harder: The Biohacker's Guide to Getting the Body and Mind You Want” launches Feb. 28, 2023. IndieBound / Barnes & Noble / Apple Books / Amazon 9th Annual Biohacking Conference: https://biohackingconference.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Feb 1, 2023

IN THIS EPISODE OF THE HUMAN UPGRADE™… you’re going to learn how to work with your own biology, adapt to adversity, and get resilient AF. Doctor, educator and entrepreneur Dr. Molly Maloof joins the show in person in Austin, Texas, to talk about her debut book, “ The Spark Factor: The Secret to Supercharging Energy, Becoming Resilient, and Feeling Better Than Ever .” For women biohackers, it’s all about energy—and hormones. “Cycles are exactly why the way guys biohack doesn’t always work for us [women]; we have hormonal and physiological differences, and importantly, different biological imperatives, from an evolutionary standpoint,” she says in her new book. She last appeared on episode #706 and talked about how blood sugar powers your energy. This time, she explains why mitochondrial dysfunction is at the root of the collective human energy crisis and what you can do about it. Dr. Molly says four culprits reduce your energy capacity: inactivity, overeating and poor nutrition, too much stress and social disconnection. "Spark Factor" outlines clear and actionable steps for women on how to make, charge, use, tune, and plug in your own batteries. New to biohacking? Start where you are. More advanced biohacker? You’ll learn tips and tweaks to get you to another level. Molly offers low-tech and tech-free guidance, too. It’s up to you where to start and how far you want to take it. Her unique view of human performance incorporates technology and psychedelics. In this broad conversation, she covers sex and relationships, too. Watch this episode on YouTube ! WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Support Your Neck & Fight Aging: www.envypillow.com and use DAVE15 to get 15% off any pillow Dave Asprey’s NEW Book! “Smarter Not Harder: The Biohacker's Guide to Getting the Body and Mind You Want” launches Feb. 28, 2023. Pre-order yours today: IndieBound / Barnes & Noble / Apple Books / Amazon 9th Annual Biohacking Conference: https://biohackingconference.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jan 27, 2023

IN THIS EPISODE OF THE HUMAN UPGRADE™… board-certified OB/GYN and “menopause warrior” Mary Claire Haver, M.D. , joins the show to give women a toolkit to manage what comes before, during and after menopause. She explains the science of women’s hormones, physiology and brain during the menopausal transition. She breaks down the studies, risks, and age timing of Hormone Replacement Therapy. She gives you information you can use to both help yourself and ask for help from medical professionals. She arms you with actions that work based on what is happening to your biology and brain chemistry during the years leading up to and after menopause. “When I talk about the menopausal toolkit, HRT is just one small part of what I counsel patients about,” Dr. Haver says. “We talk about nutrition, we talk about exercise, we talk about stress reduction, we talk about sleep, we talk about possible other pharmaceuticals. And of course, we talk about supplementation. It's like a tackle box and everything is important.” Although Dr. Haver’s career included taking care of women at all life stages, she didn’t expect to experience the shocks of her own menopause. So, she went looking for answers and took action along the way. She changed the entire focus of her medical practice to menopause. She also channeled the power of social media to provide menopause education and reaches more than 2 million on her TikTok channel alone. Her new book, “ The Galveston Diet: The Doctor-Developed, Patient-Proven Plan to Burn Fat and Tame Your Hormonal Symptoms ," lays out three specific action areas: intermittent fasting, anti-inflammatory nutrition, and fuel refocus. Menopause is having a moment. (As Lizzo would say, “It’s About Damn Time.”) From investor-backed start-ups in a $6B market to celebrity-led wellness brands to demands for more science—women, and women medical professionals, are changing mid-life menopause dynamics. Watch this episode on YouTube ! WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Liquid Ketones for Better Energy, Focus and Endurance . https://hvmn.com , use code DAVE to get 20% off Dave Asprey’s NEW Book! “Smarter Not Harder: The Biohacker's Guide to Getting the Body and Mind You Want” launches Feb. 28, 2023. Pre-order yours today: IndieBound / Barnes & Noble / Apple Books / Amazon 9th Annual Biohacking Conference: https://biohackingconference.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jan 25, 2023

IN THIS EPISODE OF THE HUMAN UPGRADE™… Susanna Soeberg, Ph.D., a Danish researcher, international scientist and expert in cold and heat therapy for health and performance, explains how you can harness the massive benefits of cold water immersion (winter swimming), sauna, breathing, and your metabolism. When it comes to biohacking, a few things rise to the top and make a pretty big difference in your body and brain. Through her research, Susanna discovered the minimum threshold of cold and heat exposure for health benefits. We get right into that on the show. She also works with functional breathing during cold environmental conditions and cold water immersion, especially winter swimming. Have you been considering this biohack for awhile? Baby steps won’t get you there—prepare to go all-in with the cold. “You could take cold showers, for sure,” Susanna says, “but it's not going to activate your parasympathetic nervous system in the same way as submerging yourself into cold water.” Earning a Ph.D. in metabolism at the University of Copenhagen set her on course to focus her expertise on ways metabolism works for and against you—and what you can do to improve your metabolic profile. She researches obesity, Type 2 diabetes and insulin management, as well as how brown and white adipose tissue (fat) function differently within the human body. In Susanna’s new book, “ Winter Swimming: The Nordic Way Towards a Healthier and Happier Life ,” she describes the benefits of winter swimming and cold water immersion on your physiology, mental health, and capacity for resilience. Watch this episode on YouTube ! SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://www.soeberginstitute.com and use code DAVE for a special discount on Susanna Soeberg’s 3-week course, The Thermalist CureTM. Opportunity : Breath, Cold, Stress & Resilience Conference , Feb. 18, 2023. Presentations by Susanna Soeberg, James Nestor and other experts. Register here . WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Capture Life Force Energy: https://leelaq.com , use discount code DAVE10 to get 10% off sitewide Must-Have Magnesium: https://magbreakthrough.com/dave , use code DAVE10 to get a 10% discount 9th Annual Biohacking Conference: https://biohackingconference.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jan 20, 2023

Leela Quantum Tech sponsored this episode. IN THIS EPISODE OF THE HUMAN UPGRADE™… you’ll learn why energy frequencies have such a powerful influence on human physiology. Skeptics take note: science backs this up. Philipp Samor Von Holtzendorff-Fehling introduced quantum energy on episode #809 and its benefits on body function, cellular voltage and chakra energy. He returns to the show with exciting new research that further validates the power of this energy and its frequencies on human physiology. “Energy and frequency—that’s where the real truth is.” Philipp says. “And that's where the real life also is.” Leela Quantum Tech creates blocs (Infinity, Quantum, Travel), frequency cards, H.E.A.L. capsules, and other products charged with quantum energy. The products have been through single- and double-blind, randomized studies and tests. This research has measured mental and physical energy, organ function, neutralization of radioactive particles, protection against pesticides and herbicides, and much more. Studies also explored how quantum energy affects ATP production, HRV (heart rate variability) and food allergies. You can feel and measure the effects. And dark field microscopy studies (placebo-controlled and double-blind) performed by Dr. Beverly Rubik in the U.S. and the BESA institute in Austria looked at the physical effectiveness of Leela Bloc technology. SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://leelaq.com and use code DAVE10 to get 10% off. Watch this episode on YouTube ! WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Protein Bars with All the Good Stuff and None of the Crap: https://rowdybars.com , use code DAVE to get 10% off 9th Annual Biohacking Conference: https://biohackingconference.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jan 18, 2023

IN THIS EPISODE OF THE HUMAN UPGRADE™… Harvard psychiatrist, researcher and assistant professor Christopher Palmer, M.D., introduces a bold new premise about the root cause of mental illness based on decades of research. Dr. Palmer integrated existing theories and research into one unifying theory—the brain energy theory of mental illness that’s rooted in your metabolism. Through his research, he initially pioneered using a medical ketogenic diet to treat psychiatric disorders. In this conversation, you’ll learn how he went even further to uncover the connection between mental health and metabolic disorders of the brain. That connection lies in mitochondrial dysfunction or dysregulation. His new book, “ Brain Energy: A Revolutionary Breakthrough in Understanding Mental Health and Improving Treatment for Anxiety, Depression, OCD, PTSD, and More ,” also explains the increased risk for mental disorders in all metabolic conditions, including diabetes, heart attacks, strokes, pain disorders, obesity, Alzheimer’s disease, and epilepsy. “Once you see the big picture of metabolism and all of the things that influence metabolism, you actually can see novel ways to intervene,” Dr. Palmer says. “And you can also raise some red flags about some of our current treatments.” Watch this episode on YouTube ! WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Mineral-rich Salt—Unrefined & Unprocessed: https://oryxdesertsalt.com , use code DAVE10 to get 10% off Sleep Solutions for High Performance: https://sleepbreakthrough.com/dave , use code DAVE10 to get an extra 10% off 9th Annual Biohacking Conference: https://biohackingconference.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jan 13, 2023

IN THIS EPISODE OF THE HUMAN UPGRADE™… you’ll meet Gloria Mark, Ph.D., who studies how digital media impacts people's lives. Her research specifically covers how attention is affected by, and has changed, with the rise of the digital age. She’s found that attention span now averages 47 seconds on a screen—and even that’s shrinking. As a Chancellor’s Professor of Informatics at the University of California-Irvine researching human-computer interaction, Gloria examines how people handle multitasking, task-switching, interruptions, and emotions. Her new book “ Attention Span: A Groundbreaking Way to Restore Balance, Happiness and Productivity ” looks at human technology use from a psychological perspective. “In the thousands of hours that I have studied people in the course of their daily work, I have heard a common sentiment,” Gloria says in her book. “People report that they are overworked and exhausted because they have to deal with too much information and too many messages.” This conversation gets into the science of attention, the stress it’s causing, plus real solutions for how you can regain focus with your personal technologies. You’ll learn: How to recognize the four main types of attention; What consequences of constant interruption do to your stress levels and productivity; How to achieve focus, rhythm and balance in a day filled with attention-switching; How to structure a flow state within your day; and What four things you can do to gain agency in the digital world. Watch this episode on YouTube ! Shield Yourself from EMFs: https://quantumupgrade.io , use code DAVE to get a two-week free trial Knowing Labs : Test Your Own Biology: https://knowinglabs.com/dave , use code dave to save 20% off any test kit 9th Annual Biohacking Conference: Come join like-minded people June 22-24 in Orlando, Florida, for three days of awesome! You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. https://biohackingconference.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jan 10, 2023

IN THIS EPISODE OF THE HUMAN UPGRADE™… you’ll meet Robert Waldinger, M.D., who leads an extraordinary scientific study on happiness that’s still going strong after eight decades. The study set out to understand human health by what made people thrive . Since 1938, the Harvard Study of Adult Development has tracked two groups of men and their families with the goal of discovering what really makes for a good life. Along the way, thousands of questions were asked, and hundreds of measurements were taken—from brain scans to blood work. Three strong themes emerged from the study: Social connections are really good for you. Loneliness kills. It’s the quality of your close relationships that matters. Good close relationships don’t just protect your body , they protect your brain . Dr. Waldinger combined those lifelong case studies with modern psychological research in his new book, co-authored with Marc Schulz, Ph.D., “ The Good Life: Lessons from the World's Longest Scientific Study of Happiness ." This discussion gives you real-life tools to hack your happiness. You’ll learn things like: how relationships improve your physical, mental and emotional health. (More than you know!) how to evaluate the effect of your relationships on your well-being. (Don’t be dragged down.) what social fitness is and how to practice it. (Yes, it’s a flex.) ways to enliven and energize your relationships. (Energy totally matters.) why casual and work relationships matter more than you think. (A surprisingly big contribution.) Watch this episode on YouTube ! Don’t Miss This! Dr. Waldinger’s TEDtalk about the study is one of TED’s Top 10 episodes and viewed more than 43 million times. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Energize Your Brain & Body : https://nootopia.com/davegenius , use code DAVE10 to get an extra 10% off Clear Out Zombie Cells with Senolytics : https://neurohacker.com/dave , code ASPREY to get an additional 15% off 9th Annual Biohacking Conference: Come join like-minded people June 22-24 in Orlando, Florida, for three days of awesome! You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. https://biohackingconference.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jan 7, 2023

Neurohacker Collective sponsored this episode. IN THIS "UPGRADE SPOTLIGHT" EPISODE OF THE HUMAN UPGRADE ™… you’re going to learn about the zombie cells taking up valuable space in your body and how you can clear them out with senolytics. When these zombie cells accumulate (formally called senescent cells), they negatively impact how you age. You may experience symptoms like joint discomfort, low mental and physical energy, poor metabolic health, and diminished muscular response when you work out. Naturopathic physician Greg Kelly joins the show from Neurohacker Collective , where he’s director of Product Development. His expertise includes nootropics, anti-aging and regenerative medicine, weight management, sleep, and the chronobiology of performance and health. The hallmarks of aging include nine characteristics that organisms all the way up to humans share as we age, Dr. Kelly explains. One of those characteristics is senescent cells. This discussion gets into the reasons why senescence happens, the science of senolytics, exciting new research, and new product developments that help bodies naturally eliminate senescent cells. This means a better aging process for you! SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://neurohacker.com/dave and code ASPREY to get an additional 15% off . You can trial Qualia Senolytic for up to 100 days with a full 100% money-back guarantee. Watch this episode on YouTube ! 9th Annual Biohacking Conference: Come join like-minded people June 22-24 in Orlando, Florida, for three days of awesome! You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. https://biohackingconference.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jan 6, 2023

IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... the new year starts off with a Legacy Upgrade conversation between Dave Asprey and Dr. Andrew Weil recorded live at True Food Kitchen in Phoenix, Arizona. Dr. Weil’s an internationally known pioneer and leader in integrative medicine. He’s also a Harvard-trained botanist and medical doctor recognized worldwide for his views on living a healthy lifestyle, his philosophy of healthy aging, and his critique of the future of medicine and health care. This broad discussion both hits the high points and goes deep into nutrition, aging, energy, lifestyle, and, of course, tea. Specifically, vibrant green matcha. (Or as Dave says, “It looks like green paint.”) There’s a lot of knowledge and humor shared, as well as hard-hitting truths: “One of the most toxic cultural messages here is that the value of life diminishes with aging,” Dr. Weil says. His five pillars of good health touch on foundational elements that contribute to your core vitality and life force. Eat right! Learn the principles of nutrition and apply them to your life Get regular physical activity Learn and practice methods to neutralize the harmful effects of stress Maintain emotional and intellectual connectivity as you go through life Attend to your spiritual well-being More about Dr. Andrew Weil : He founded the Andrew Weil Center for Integrative Medicine at the University of Arizona. He champions the use of medicinal plants and alternative medicine, as well as the reform of medical education. He’s a clinical professor of medicine and a professor of Public Health at the University of Arizona and the author of more than a dozen books on health, wellness and optimal living. SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS : Go to www.matcha.com and use code Bulletproof15 to save 15% off sitewide. Watch this episode on YouTube ! WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! A Probiotic to Ease Stress: https://www.omnibioticlife.com/DAVE , use code DAVE20 to get 20% off . 9th Annual Biohacking Conference: Come join like-minded people June 22-24 in Orlando, Florida, for three days of awesome! You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. https://biohackingconference.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jan 4, 2023

IN THIS EPISODE OF THE HUMAN UPGRADE™… Humble The Poet joins the show to talk about a unique perspective on love. You’ll learn: what “real” love means (hint: it’s not found or earned) and how to recognize it in your life. how to shift away from a mindset of earning more, achieving more, and gaining more attention so you can clear pathways for love to enter and flourish in your life how to ditch restrictive “resolutions” (that fail more often than they succeed) and instead set intentions that allow you more freedom to love yourself and others. This Canadian-born rapper, spoken-word artist, poet and international bestselling author began reciting spoken word poetry in coffee shops more than a decade ago. That creative outlet turned into an adventure that crossed genres, mediums and oceans. His style stimulates audiences with ideas that challenge conventional wisdom. His first two books, “ Unlearn ” & “ Things Nobody Can Teach Us ” became international bestsellers. His newest book focuses on self love, love for others, defining love in a different way, and how to ease up on expectations that may be holding you back: “ How to Be Love(d): Simple Truths for Going Easier on Yourself, Embracing Imperfection & Loving Your Way to a Better Life .” “I’m writing this because I’m desperate,” he says in the book. “Desperate to realize love, accept love, and learn how I keep f**king it up.” Watch this episode on YouTube ! WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Comfort Options for Hot & Cold Sleepers: https://sleep.me/daveasprey , use code ASPREY for 25% off your purchase Must-Have Magnesium: https://magbreakthrough.com/dave , use code DAVE10 to get a 10% discount . Kickstart Autophagy: https://timelinenutrition.com/DAVE , use the code ASPREY10 to get 10% off any plan See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Dec 30, 2022

IN THIS “BEST OF” EPISODE OF THE HUMAN UPGRADE™… … Ari Whitten, Ph.D. (Cand.), CES, PES , explains how to double your energy through improved resilience, cell defense, nutrition and supplementation. In his newest book, “ EAT FOR ENERGY: How to Beat Fatigue, Supercharge Your Mitochondria, and Unlock All-Day Energy ,” Ari explains that 5.4 million adults in the U.S. have been diagnosed with chronic fatigue syndrome (the most severe case of fatigue). However, the true fatigue epidemic affects 50 to 100 times more people with many experiencing some level of being flat-out tired as hell. This conversation gets right into the role of mitochondria in human energy. The cause of fatigue is mitochondrial dysfunction, Ari says. The biggest factors that affect your mitochondria include: Circadian rhythm dysregulation and poor sleep Carrying too much body fat and too little muscle mass Poor gut and microbiome health Blood sugar dysregulation Nutritional toxicities and deficiencies Neurotransmitter and hormone imbalances Ari recommends science-backed ways that you can get your mitochondria moving, dial in your nutrition and upgrade your brain, gut and hormones. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Mattress Temperature Tech: https://www.eightsleep.com/dave , use code dave to save $250 on the Pod Pro A Cleaner Nicotine Alternative: https://lucy.co , use code DAVE20 for 20% off your first order of pouches, gums or lozenges 9th Annual Biohacking Conference: Come join like-minded people June 22-24 in Orlando, Florida, for three days of awesome! You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. https://biohackingconference.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Dec 28, 2022

IN THIS “BEST OF” EPISODE OF THE HUMAN UPGRADE™… … Steven Gundry, M.D. , explains that ketones aren’t the fat-burning molecules you think they are. Ketones actually work to enhance health, weight loss, and longevity by acting as signaling molecules that stimulate your mitochondria. A cellular process known as “mitochondrial uncoupling” happens. He debunks common myths about keto in his newest book, “ Unlocking the Keto Code: The Revolutionary New Science of Keto That Offers More Benefits Without Deprivation ,” and shares eight “keys” that unlock the keto code: Intermittent fasting or time-controlled eating Polyphenols Dietary fiber Fermented foods Polyamines Cold temperatures Hot temperatures Red light therapy Upgrading your nutrition with keto gets even simpler in this conversation that gives you real food examples of how to ignite your mitochondrial uncoupling process without a monotonous, limiting, high-fat diet. SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Get 30% off products at https://gundrymd.com . Use code DAVE30 at checkout. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Clean up Zombie Cells with Senolytics: https://neurohacker.com/dave , use code Asprey15 to save 15% Cooler Temps for Deeper Sleep: https://www.chilisleep.com/ , use code HUMANUPGRADE20 to save 20% on the Dock Pro Sleep System. Learn more: Upgrade Spotlight: Improve Your Sleep With a Cooler Body Temp – ChiliSleep – #923 Business Growth With SEO: https://www.stephanspencer.com , get a FREE consultation See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Dec 23, 2022

IN THIS “BEST OF” EPISODE OF THE HUMAN UPGRADE™ … natural vision expert Claudia Muehlenweg explains how you can take better care of your eyes and improve your vision. Her work is based in the Bates Method . She focuses on finding the root cause of blurry vision instead of using symptomatic treatments like glasses, contacts or surgery that actually can make eyesight worse in the long term. For nearly 15 years, Claudia’s taught eyesight improvement for presbyopia, myopia, astigmatism, hyperopia, strabismus, convergence insufficiency, and eye diseases such as cataracts, macular degeneration and glaucoma. She also helps people restore clarity after corrective surgeries like LASIK have worn off. Claudia starts with root causes in your body, including nervous system regulation. She then brings in bodywork, breathwork, rest, light and movement healing methods. Listen on to get practical solutions and essential Dos and Don’ts for good eyesight. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! A Pre-Alcohol Probiotic to Offset a Rough Morning After: https://zbiotics.com/dave , use code DAVE to save 15% off your first order. Learn more: The Bacteria That Lets You Drink Alcohol Again – Zack Abbott, Ph.D. – #1000 Biostack for High Performance: https://vatellia.com , use code DAVE2022 to save 10% or subscribe and save 15% + receive a free bottle of Kale Buster Sleep Better on Natural Memory Foam: https://myessentia.com/daveasprey , use code DAVE to get an extra $100 off an Essentia mattress purchase on top of Essentia’s Holiday 25% off sale. Through Dec. 31, 2022, only. Learn more: Mattress Smarts 101 for High-Performance Sleep – Jack Dell’Accio – #875 See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Dec 21, 2022

In this Episode of The Human Upgrade™ … Dave talks with Rachelle Copeland about putting her energy into healing facial injuries and building new tissues—starting with the central nervous system. Rachelle experienced an accident that injured her face, teeth, nerves and jaw. She wants to heal quickly and avoid scarring and long-term damage while also managing the accompanying emotional trauma. This intervention looks at ways to heal and recover both internally and externally, covering suggestions such as: EMDR, Tapping, EFT for physical and emotional trauma ( What Is EMDR and How Does It Work? , Nick Ortner: The Tapping Solution for Pain Relief – #219 , Tap into Tapping: The EFT Episode – Dawson Church # 474 ) Jaw misalignment ( Dr. Dwight Jennings: TMJ, Jaw Pain, & Substance P – #179 ) Vagal nerve ( Stephen Porges: The Polyvagal Theory & The Vagal Nerve – #264 , The Nervous System Circuitry of Safety, Sound & Gratitude – Stephen Porges #573 ) Hyperbaric therapy Craniosacral work Inflammation Oral and topical cayenne Red and infrared, LED or laser light therapy Ozone therapy Supplements to support healing Enzymes If you’re recovering from injury, take a listen to this episode for tips and resources on how to heal. Note: The "Interventions With Dave” recommendations are designed to help you upgrade yourself and your biology so you can perform better at everything you do. They are not, however, a substitute for advice or treatment by a trained medical professional that may be needed for specific health conditions, illness or injury. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Vascular System Protection https://calroy.com/dave , save on a 3-pack to protect your blood vessels from vulnerable plaque Get Fit in Five Minutes: https://www.carolbike.com , use code HumanUpgrade to get 2 years of free membership (a total savings of $360) on the CAROL Bike 2.0 and a 100-day home trial. 9th Annual Biohacking Conference: Come join like-minded people June 22-24 in Orlando, Florida, for three days of awesome! You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. https://biohackingconference.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Dec 16, 2022

Viome sponsored this episode. IN THIS EPISODE OF THE HUMAN UPGRADE™… entrepreneur and philanthropist Naveen Jain joins the show in person at the Beverly Hilton to talk about new developments in the human biome—particularly the oral microbiome. Turns out, there may be more density in your gut microbiome, but there’s more diversity in your oral microbiome. Naveen’s company, Viome , built an AI-driven platform that analyzes the interaction between food, your body’s biomes, and your cells from at-home tests. Your results are used to develop precise ways of eating and taking supplements that prevent and can even help reverse chronic disease. They’ve so far collected 425,000 samples showing 600 trillion data points. The newest Viome test kit takes a look at your oral health. Viome prepares custom supplements, probiotics and prebiotics with the exact ingredients in the exact dosages you need based on your personal test results. This customization is important because supplements are not universally healthy, more isn’t better, and consuming nutrients and biotics you don’t need can actually do more harm than good. Custom formulations work with and for your own physiology. Viome testing also helps you see your personal health trends over time. Your tests could show different results at six months or a year. Then, your supplements would be adjusted to your changing physiology. Check out Viome’s at-home test kits: Oral Health Intelligence: coming soon! Full Body Intelligence (gut, cellular, oral health) Health Intelligence (gut, cellular health) Gut Intelligence (gut health) Cancer Detect (oral & throat) SPECIAL OFFER FOR LISTENERS OF THE HUMAN UPGRADE: Go to https://viome.com/dave and use code DAVE10 to get 10% off tests and 10% off a 12-month subscription Watch this episode on YouTube ! WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Nature’s Nootropic: https://trukava.com , use code DAVE15 to get 15% off Upgrade Your Air Quality: https://hypoair.com/Dave/ Mattress Temperature Tech: https://www.eightsleep.com/dave , use code dave to save $250 on the Pod Pro See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Dec 13, 2022

Pendulum sponsored this episode. IN THIS EPISODE OF THE HUMAN UPGRADE™ …molecular biologist and biochemist Colleen Cutcliffe, Ph.D., returns to the show with brand new science about your gut. She’s a regular guest because she and her team at Pendulum continue to uncover innovative ways to improve your gut health, your metabolism, your immune system, how your brain works and how long you live. This time, Akkermansia’s back in the spotlight, with more than 300 new studies showing connections to weight, metabolism and immunity. A unique and novel probiotic strain (species of bacteria) naturally found in your gastrointestinal tract, Akkermansia muciniphila, directly interacts with your gut lining and helps regulate the mucus lining in your gut. Now, there’s growing evidence showing Akkermansia to be a keystone bacterial strain. This conversation dives into the latest research and what it means for you. You’ll learn how to apply this new knowledge and how to boost Akkermansia in your gut. SPECIAL OFFER FOR LISTENERS OF THE HUMAN UPGRADE: Go to https://pendulumlife.com and use promo code DAVEVIP to get 20% off your first month of membership. Watch this episode on YouTube ! A Pre-Alcohol Probiotic to Offset a Rough Morning After: https://zbiotics.com/dave , use code DAVE to save 15% off your first order. Sleep Better on Natural Memory Foam: https://myessentia.com/daveasprey , use code DAVE to get an extra $100 off an Essentia mattress purchase on top of Essentia’s Holiday 25% off sale. Through Dec. 31, 2022, only. Go Deep on Relaxation & Sleep: https://balooliving.com/dave , use code DAVE for a special discount. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Dec 9, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE™ … you’ll find out that kids are killing themselves more often and at younger ages. Suicide prevention expert Dr. Mark Goulston joins the show to discuss the very real and very urgent topics of youth mental health and suicide—from pre-teens to teens to young adults. These issues concern everyone , not only families, educators or professionals who connect with young people. Here’s why: Suicide shows up in the top three causes of death in young people between the ages of 10-24, according to 2020 stats from the Centers for Disease Control and Prevention (CDC) WISQARS Leading Causes of Death Reports . Young people are hurting. The National Alliance on Mental Illness reports that nearly 20% of high school students say they’ve had serious thoughts of suicide and 9% have made an attempt to take their lives. Dr. Mark explains that many young people struggling mentally and emotionally feel like they're a burden to everyone. And they don’t have confidence that parents can help them feel better. You’ll learn a lot during this conversation, such as: factors driving teen mental health issues and teen suicide. what’s going on in the teen brain from a developmental perspective that leads them to think that death is a preferable alternative to working through life situations. signs or red flags that a teen is struggling. how parents and adults often can diminish or dismiss teens’ emotions, situations with friends or love relationships. what emotional intelligence skills are most useful for parents/adults to better understand teens. how to talk to teens—whether you’re a parent or a caring adult in a teen’s life. how to improve listening in a culture dominated by tech. how to listen to teens and help them realize and understand their emotions—without cutting them off, interrupting them, or jumping to advice and solutions. when to seek professional intervention. More about Dr. Mark Goulston : He's a retired psychiatrist, former UCLA professor of psychiatry and former FBI and police hostage negotiation trainer. He recently received the “Shine the Light Media Award” from the Los Angeles County Medical Association for bringing attention to teen mental health and suicide. He’s the author or co-author of nine books: “ Just Listen: Discover the Secret to Getting Through to Absolutely Anyone ,” ranks in the 15 Best Communication Skills Books of All Time . Watch this episode on YouTube ! Biostack for High Performance: https://vatellia.com , use code DAVE2022 to save 10% or subscribe and save 15% + receive a free bottle of Kale Buster Get Fit in Five Minutes: https://www.carolbike.com , use code HumanUpgrade to get 2 years of free membership (a total savings of $360) on the CAROL Bike 2.0 and a 100-day home trial. Business Growth With SEO: https://www.stephanspencer.com , get a FREE consultation See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Dec 6, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE™ … you’ll learn about a new holistic framework for self-healing and how to heal yourself with prompts, tools and actionable tips. Using the tenants of holistic psychology, Nicole LePera, Ph.D., created a different way to reach people and equip them with the tools necessary to heal themselves. Holistic psychology focuses on the mind, body, and soul in the service of rebalancing the body and nervous system and healing unresolved emotional wounds. It’s all about a daily practice of creating your own wellness by: seeing yourself from a new perspective, breaking negative patterns, healing from your past, and creating your conscious self. Nicole, the author of the New York Times Bestselling Book “ How to Do the Work: Recognize Your Patterns, Heal from Your Past, and Create Your Self ,” builds on that theme and goes even deeper with her newly published “ How to Meet Your Self: The Workbook for Self-Discovery ” workbook. In this conversation, you’ll find out how to: objectively and compassionately observe the physical, mental, and emotional patterns that keep you stuck. deep dive into your ego, trauma and emotions so you can safely do the inner work that can transform your outer world. change ingrained beliefs and habits so you can move toward realizing your authentic self. Watch this episode on YouTube ! WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! A Cleaner Nicotine Alternative: https://lucy.co , use code DAVE20 for 20% off your first order of pouches, gums or lozenges Mattress Temperature Tech: https://www.eightsleep.com/dave , use code dave to save $250 on the Pod Pro Test Your Own Biology: https://knowinglabs.com/dave , use code dave to save 20% off any test kit See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Dec 2, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™… Dan Buettner joins the show to talk about the origins and food foundations of Blue Zones. He discusses how they were discovered, what makes them different, and what’s changed for people living there over the past few decades. And the big question—is it still possible to live to 100? Dan, an explorer, National Geographic Fellow, award-winning journalist and producer, and photographer, has studied and written extensively about the five places in the world—dubbed Blue Zones—where people live the longest, healthiest, and often happiest lives. He’s partnered with epidemiologists, anthropologists, medical researchers, demographers, and statisticians to take a data-based approach to everything from genetics to census data. Combining this intensive research with cultural immersion, Dan’s brought out aspects of Blue Zones lifestyles—like food and social connection—that form a foundation for human life quality and longevity. He’s the bestselling author of a series of Blue Zone books. In Dan’s latest Blue Zones adventure, he took a road trip across the United States to explore food and communities. He found that pockets of Blue Zones do exist throughout the U.S. He talked to heritage cooks passing on recipes to younger generations. He uncovered the traditional roots of plant-forward cuisine in the United States and presents both traditional and revolutionary ideas in vegetarian food in his newest book, “ The Blue Zones American Kitchen: 100 Recipes to Live to 100 .” Stunning photography and recipes show the vitality of both food and people from five distinct areas: Indigenous, Native & Early American, African American, Latin American, Asian American and Regional and Contemporary American. Dan also dug deep into the country’s food history and brings to light the dramatic changes in food processing, regulation, government intervention, and leadership choices that have influenced food supply. He combed through 60 oral histories, scientific reports and academic papers to reconstruct traditional American diets. In “The Blue Zones American Kitchen,” you’ll find out why the 1970s were the worst decade for America’s food environment. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Upgrade Your Air Quality: https://hypoair.com/Dave/ Nature’s Nootropic: https://trukava.com , use code DAVE15 to get 15% off Must-Have Magnesium: https://magbreakthrough.com/dave , use code DAVE10 to get a 10% discount . Learn more: Magnesium: The Master Mineral That Conquers Stress – BiOptimizers – #669 See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 29, 2022

( ZBiotics sponsored this episode.) IN THIS EPISODE OF THE HUMAN UPGRADE ™… you'll find out how to counter the sometimes rough morning after you have alcohol. The key is a new genetically engineered pre-alcohol probiotic drink. Great timing as you head into the holiday season of celebrations. Zack Abbott, CEO & co-founder of ZBiotics , joins this 1,000th episode of the podcast to talk about new discoveries in alcohol metabolism, genetic engineering and GMOs (used in a good way!), and the power of microbes. Ever wondered why you feel like crap the morning after drinking alcohol? The cause is a byproduct called acetaldehyde that forms in your gut when you drink alcohol. The ZBiotics Pre-Alcohol Probiotic Drink breaks down acetaldehyde while you drink so you can feel better the morning after. Prior to starting ZBiotics, Zack, who has a Ph.D. in microbiology and immunology, worked in clinical trial design, researched HIV vaccines, and pursued novel antibiotics in both academia and industry. He invented the ZBiotics proprietary technology using genetic engineering to develop new probiotics—ones with specific, unique abilities to improve your daily life. He’s proving through science that incredible things can be done with GMOs and genetically engineered microbes. SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://zbiotics.com/dave and use code "dave" to save 15%. Watch this episode on YouTube ! Biostack for High Performance: https://vatellia.com , use code DAVE2022 to save 10% or subscribe and save 15% + receive a free bottle of Kale Buster Harness Cold to Improve Health & Performance: https://www.cryobuilt.com Business Growth With SEO: https://www.stephanspencer.com , get a FREE consultation See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 25, 2022

In this Episode of The Human Upgrade™...​ Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month. Sperm that swim together increase their chances of fertilization Late-night eating is worse than you thought Metabolic markers can be measured through your sweat Eye movements during REM sleep could delete unwanted memories EPISODE SPONSOR: Humic & fulvic minerals provide critical cellular support. Go to https://www.beamminerals.com and use code DAVE20 to get 20% off . Learn more: How Minerals Combat Glyphosate’s Harm – Caroline Alan – #948 . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 22, 2022

Timeline Nutrition sponsored this podcast. IN THIS EPISODE OF THE HUMAN UPGRADE ™… immunologist Anurag Singh, M.D., Ph.D., MBA, Chief Medical Officer at Amazentis, joins the show to talk about urolithin A’s connection between inflammation, aging and your mitochondria. Urolithin A activates mitophagy and renews your mitochondria. “It takes all the cellular garbage that has been accumulating over the aging process,” Dr. Singh explains. “It revs it up, so it recharges. And so now, you're cleaning your metabolic waste products much more efficiently and they become the building blocks. This is mitochondrial biogenesis, and that means newer, healthy mitochondria coming in.” This new conversation takes an exciting turn into immunity and your immune system’s two lines of defense: innate and adaptive. You’ll learn: how inflammation plus aging (AKA inflammaging) contributes to a weakened immune system and a growing incidence of cancer as you age; how inflammaging and cancer are connected to mitochondrial dysfunction specifically during the aging process; and how to approach your immune health differently with this new knowledge. A new study recently published in Immunity looks at how immune cells fight cancer better with a focus on immune modulation, immune cell exhaustion and immune responses. “A lot of urolithin A is anti-inflammatory, but a lot of it is immune modulation," Dr. Singh says. "So, it takes a rewiring of the immune system and makes it more conducive to stopping harmful immune responses.” Watch this episode on YouTube ! SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: To learn more about the benefits of urolithin A, go to https://www.timelinenutrition.com and use code UPGRADE10 to get 10% off the plan of your choice. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Go Deep on Relaxation & Sleep: https://balooliving.com/dave , use code DAVE for a special discount. Must-Have Magnesium: https://magbreakthrough.com/dave , use code DAVE10 to get a 10% discount . Isometrics for Cardiovascular Health : https://www.zona.com , use code DAVE2022 to get $150 off the Zona Plus. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 18, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™… Robynne Chutkan, M.D., joins the show to talk about a topic that’s foundational to biohacking—resilience. More specifically, resilience that starts in the gut. You’ll learn: how your microbiome continually evolves and why that matters to the state of your gut and body functions. how to strengthen the antiviral defenses located in your gut. why your body’s own ability “to resist, heal, and recover from viruses is vastly superior” to pharmaceuticals. what to do before taking antibiotics to protect your gut, as well as what you can do to rehab your microbiome after antibiotic use. “Being on the winning team when battling viruses isn’t because of good luck, or coincidence, or variations in viral virulence,” Dr. Chutkan explains in her newest book, “ The Anti-Viral Gut: Tackling Pathogens from the Inside Out .” "It’s due to differences in us, the hosts, and our defenses, and those differences are what determine your outcome. Put another way: it’s less about the potency of the pathogen and more about the health of the host.” Dr. Chutkan is a Yale- and Columbia-educated integrative gastroenterologist who’s been advancing knowledge and education about gut health for decades. Nearly 20 years ago she founded the Digestive Center for Wellness to help people get to the root issue of their digestive issues and improve their gut health. Watch this episode on YouTube ! WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Brain Training with Sound & Vibration: Change unwanted behaviors, reduce negative self-talk, and enhance motivation and performance. Go to www.braintap.com/dave to get 30% off Must-Have Magnesium: https://magbreakthrough.com/dave , use code DAVE10 to get a 10% discount . Get Fit in Five Minutes: https://www.carolbike.com , use code HumanUpgrade to get 2 years of free membership (a total savings of $360) on the CAROL Bike 2.0 and a 100-day home trial. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 15, 2022

Eight Sleep sponsored this podcast. IN THIS EPISODE OF THE HUMAN UPGRADE ™… you’ll learn about the intimate relationship between performance and sleep and how you can hack both with a combination of tech and lifestyle. Matteo Franceschetti joins the show to talk about high performance—something he experienced in athletics, business and life. He was a competitive athlete in his native Italy and a race car driver across Europe. He started two clean-tech companies on two continents. He also worked at the top tier of the international legal world The one thing he didn’t excel at was sleep. So, he co-founded Eight Sleep nearly a decade ago to hack sleep in all the ways that fuel human potential, performance and energy. Eight Sleep mattress and mattress pad technology redesign sleep with AI and machine learning models to track your nighttime biosignals. It’s a technology that’s catching the attention of professional athletes in sports like snowboarding, CrossFit, Formula One, and many more. SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://www.eightsleep.com/dave/ to get up to $450 off a Sleep Fit Holiday Bundle that includes the Pod 3 Cover. This is a limited-time offer. Eight Sleep currently ships within the USA, Canada, the UK, Australia and select countries in the EU. Watch this episode on YouTube ! WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Mattress Temperature Tech: https://www.eightsleep.com/dave , use code dave to save $250 on the Pod Pro A Cleaner Nicotine Alternative: https://lucy.co , use code DAVE20 for 20% off your first order of pouches, gums or lozenges Shield Yourself from EMFs: https://quantumupgrade.io , use code DAVE to get a two-week free trial See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 11, 2022

BiOptimizers sponsored this podcast. IN THIS EPISODE OF THE HUMAN UPGRADE ™… you're going to get into bed with the topic of sleep. Pretty much everyone’s favorite. In this conversation, veteran biohacker and BiOptimers co-founder Matt Gallant returns to the show with some straight talk about how to get more and better sleep. He’s spent the big bucks—about $50K he estimates—exploring, experimenting and upgrading his own sleep. He's sharing what he now knows so you can create a sleep stack that supercharges your own energy. You’ll learn about the most common sleep disruptors and what to do about them. You’ll also learn to recognize sleep stages and how to improve your sleep pathways. This fun show uncovers the practical sleep devices, wearables, supplements and lifestyle hacks that will lull you to sleep. So many times, you’re tired and you know you want to go to sleep—and yet—your body and mind just don’t connect. The new Sleep Breakthrough makes that connection for you. And when cortisol runs amok and falsely perks you up with a second wind, you’ll know what to do. More and better sleep means you’ll be a higher-performing human. So, get some tonight! SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://sleepbreakthrough.com/dave and use code DAVE10 to get an extra 10% off . Watch this episode on YouTube! WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Sleep Better on Natural Memory Foam : https://myessentia.com/daveasprey , use code DAVE to get an extra $100 off an Essentia mattress purchase on top of Essentia’s Black Friday 25% off sale plus get two FREE organic pillows ($330 value) with mattress purchase. Through Nov. 27, 2022, only. Cooler Temps for Deeper Sleep: https://www.chilisleep.com/ , use code HUMANUPGRADE20 to save 20% on the Dock Pro Sleep System Must-Have Magnesium: https://magbreakthrough.com/dave , use code DAVE10 to get a 10% discount See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 9, 2022

Alitura Naturals sponsored this podcast. IN THIS EPISODE OF THE HUMAN UPGRADE ™…… you’ll learn about skincare ingredients that can either nourish or harm your skin. You’ll find out about standards in skin care products, what “clean beauty” means, and what to look for on product labels. Andy Hnilo, founder of Alitura Naturals, joins the show to talk about skin fitness from the inside out and why using skincare products with ingredients found in nature is the way to go. That means things like pearls, meteorites, clay, CoQ10, enzymes and more. This conversation gets into ways you can get better skin by: choosing the right nutrient-rich specialty products you can apply topically; pairing natural skin products with other biohacks, like red light; making nutrition and fitness upgrades; and exploring supplements, peptides and other wellness options. Improving skin health also means avoiding fillers and chemicals. Toxins both in skin care products and the environment tremendously impact your skin. Acne no longer drives only teenage angst. Adult acne continues to rise, with women affected more than men. Acne affects more than 50% of women between the ages of 20 and 29 and more than 25% of women between the ages of 40 and 49. (American Academy of Dermatology 2012.) Andy himself struggled with acne—so he knows the toll it takes from outside appearance to inner emotional roil. So, he searched for answers: “It was the products that I was using and then also what I was ingesting,” Andy says. “What I was putting into and onto my body.” This get-smart guide to product ingredients, environmental awareness and lifestyle tips can help you find your own skin solutions. SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://alitura.com and use code humanupgrade to save 20% sitewide. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Upgrade Your Air Quality: https://hypoair.com/Dave/ Capture Life Force Energy: https://leelaq.com , use discount code DAVE10 to get 10% off sitewide Kickstart Autophagy: https://timelinenutrition.com/DAVE , use code ASPREY10 to get 10% off any plan See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 5, 2022

Analemma sponsored this episode. IN THIS EPISODE OF THE HUMAN UPGRADE ™… you’re listening to a new Upgrade Spotlight series. Once a month, these shorter episodes feature guests who get right into useful information in a Q&A style. You’ll find out how to improve your energy and upgrade your performance. You’ll also get the latest knowledge about powerful tools and technologies that allow you to change your biology and the environment around you. Introducing Analemma ! During this Upgrade Spotlight with Mario Brainovic, CEO of Analemma, you’re going to find out about a tool that transforms regular water into a supercharged, full-spectrum, coherent state. The kind of water you drink absolutely influences the quality of your life. You’ll learn the science behind Analemma and what it can do for your health and energy. Why water? You think you know the basics: stay hydrated daily, avoid plastic bottles and use a filtration system at home. Well, Analemma says water goes way beyond the basics—all the way down to your cellular level. You’re 70% water in body mass, but 99% water on a molecular level. You’re basically very clever water. The Analemma device—similar in looks and function to a magic wand—radically changes the state of drinking water. Environmental forces cause H2O molecules in drinking water to behave chaotically. At an atomic level, water molecules crash into each other constantly. Your body’s susceptible to that influence. “We found a way to bring order to this chaos,” Mario says. “When you swirl an Analemma through the water, what happens is that those same H2O molecules start forming a liquid crystalline structure. They start behaving harmonically. They, colloquially speaking, join hands.” Analemma water is not exclusion zone water. It's something different. “It also is structured water, but we came to it in a very different way,” Mario says. “The key element to it is its stability.” This conversation gets right into the science of Analemma and several studies. You’ll find out how: a new study is measuring the rise in ATP levels (in mitochondrial energy) when people drink this water. this water affects the human microbiome this water reduces your biological age by one to 12 years by regenerating your cellular system, according to GlycanAge . you get an instant balancing effect between the left and the right brain hemisphere how a cooling affect happens on your brainwaves almost instantly when drinking this water this water restores the biodiversity of infertile soil SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://analemma-water.com and use code dave10 to save 10%. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 3, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™… You’ll learn about the ways using a sauna can charge your energy, help you heal physical and mental health conditions—and science that backs that up. Sunlighten sponsored this episode. Connie Zack joins the show to talk about the far-reaching benefits of sauna use and what’s new in the field of infrared light. For more than 22 years, Connie and her husband, Aaron, have introduced infrared light therapy to 13 countries through Sunlighten. They’re leading innovations in infrared light therapy and infrared sauna manufacturing. This conversation covers a range of good things you’ll experience from using a sauna: how infrared light affects the body and triggers a biochemical cascade of benefits; how near infrared penetrates the body to interact with mitochondria; why the real magic of infrared combines both light and heat; what evidence connects infrared and detoxification—and why sweating wins; why you sleep better—without feeling exhausted—when you do a sauna session before bed; how infrared shows promising relief for those who experience depression; and practical ways to incorporate sauna into your own stack for better sleep and higher performance. Big takeaways for you: Sauna for Detox: Results from a blood-urine-sweat study support infrared for detoxification, and it’s more than just thermoregulation as traditional medicine often argues. Sauna for Depression: Chronic inflammation is associated with depression and may be a protective, inflammatory response involving thermoregulatory pathways, the immune system, serotonin system, heat shock proteins and more. Studies show that raising core body temperature can improve major symptoms of depression . Connie’s been on the show before, so check out Saunas Use Infrared to Power Detox, Immunity & Renewal – #823 to find out how infrared sauna helps you with immunity and recovery. SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://www.sunlighten.com/dave to save up to $600 on your sauna purchase. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Brain Training with Sound & Vibration: https://specials.braintap.com/dave to get 30% off A Cleaner Nicotine Alternative : https://lucy.co , use code DAVE20 for 20% off your first order of pouches, gums or lozenges Mattress Temperature Tech: https://www.eightsleep.com/dave , use code dave to save $250 on the Pod Pro See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Nov 2, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™… Joe Polish , considered “the most connected person on the planet,” shares networking strategies that help you get what you want by giving people what they want. Dave Asprey recently connected with Joe in person to talk about Joe’s new book so you can use nine genius principles to turn your business—and your personal relationships—around. If you’re not asking “what’s in it for them?” when it comes to the people in your life—clients, colleagues, family and friends—you’re missing some important opportunities. Here are a few things you’ll learn from Joe’s new book, “ What's in It for Them?: 9 Genius Networking Principles to Get What You Want by Helping Others Get What They Want ,” as a how-to guide: Deepen rapport and connect with others by identifying and reducing their suffering Update Dale Carnegie’s insights to win the right friends and influence the right people Overcome others’ intimidation tactics to find true appreciation in relationships Build character for better results than capabilities can ever give on their own Use basic marketing principles to find true love Protect your efforts from the “takers” of the world Joe did the hard work to heal from trauma and overcome addiction. He then spent years developing a genuine and generous approach to networking and building rapport. This approach propelled his business and led him to develop the Genius Network, one of the world’s most impactful networking groups for high-achieving entrepreneurs. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Harness Cold to Improve Health & Performance: https://www.cryobuilt.com Customized Nootropics for Your Own Neurochemistry: https://nootopia.com/dave , use code DAVE10 to get 10% off. Learn more on The Human Upgrade podcast: Hack Your Neurochemistry with Customized Nootropics – Mr. Noots & Matt Gallant – #861 Business Growth With SEO: https://www.stephanspencer.com , get a FREE consultation See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 28, 2022

In this Episode of The Human Upgrade™...​ Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month. • How (and why) brain cells transfer mitochondria to one another • How a newly discovered molecule stimulates hair growth • How a tired brain drives poor decision-making EPISODE SPONSOR: The Eng3 NanoVi device helps repair oxidative stress damage and support the body’s natural repair mechanisms. https://eng3corp.com/DAVE/ . Learn more: The Anti-Aging Science Behind the NanoVi Device – Rowena Gates & Hans Eng – #416 . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 27, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™… you’ll learn how a yoga practice can be a vehicle for inner transformation. This conversation looks past the popularity of yoga as a fitness trend and into its deeper potential for human development. You’ll also learn how yoga can be a way for you to explore your whole being—from physicality to emotions to thinking. “A yoga practice often can be the missing ingredient for people,” says renowned yoga master Baron Baptiste. “Often I hear, ‘I added yoga practice to my routine and regimen, and it just shifted everything for me.’ It's a very different way of working your body, mind and breath integration.” Baron devotes his own life to the study and practices of human development. For more than 30 years, he’s facilitated education through yoga principles and teachings. His power vinyasa yoga— The Baptiste Methodology—includes the physical (asana), meditation (dhyana) and inquiry (niyama). “Iyengar was one of my primary teachers,” Baron says. “One thing I borrowed from him is the rigor to a body alignment—a True North Alignment.” Baptiste Yoga is a systematic approach made up of 53 poses, or asanas, that are linked together by connective momentum and consist of five classical pillars: Drishti (gaze), ujjayi (breath), bandhas (foundation), tapas (heat) and vinyasa (flow). More about Baron Baptiste : Baron began to seriously study yoga at age 12. As the son of two of America's yoga pioneers, he’s got a great life story that highlights the transformative power of yoga. He trained extensively in all the major traditions before beginning to teach yoga in Los Angeles in the late 80s and creating Baptiste Power Vinyasa Yoga in the mid-90s. He’s worked with celebrities, Olympians and professional athletes. He founded the Baptiste Power Yoga Institute that reaches people around the world. Baron’s also a New York Times bestselling author of multiple books, Emmy-award film maker and public speaker. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Hydrate with Electrolytes: https://DrinkLMNT.com/DAVE , get a FREE LMNT Sample Pack with 8 single-serving packets for the cost of shipping ($5 for U.S. customers) A Cleaner Nicotine Alternative : https://lucy.co , use code DAVE20 for 20% off your first order of pouches, gums or lozenges Customized Nootropics for Your Own Neurochemistry: https://nootopia.com/dave , use code DAVE10 to get 10% off. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 25, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™… biohacking goes in a different direction. This frank discussion looks at the dying process and how people and those close to them (family and friends) experience death. You’ll learn about the existence of angels and the power of psychic abilities—even if you may be a skeptic. The conversation also explains what a “medical intuitive” does and how a medical intuitive facilitates energetic healings. Cool show today! And not what you might expect. Avid biohacker Julie Ryan checks a lot of success boxes: businesswoman, serial entrepreneur, author, radio show host and podcaster. She also invents surgical devices that sell globally; some have been on the market for three decades. She’s founded nine companies in five different industries. She checks a lot of unconventional boxes, too. She’s a psychic and medical intuitive. This means she can sense medical conditions and illnesses in people—like a human MRI machine. Then she facilitates energetic healings and says she does a lot of work with stem cell energy. Julie scans animals, accesses people’s past lives and senses how close to death someone is. She communicates with spirits both alive and dead. Even cooler—Julie’s psychic and medical intuitive skills are learned and she teaches those skills to others. Julie talks about the “glorious” side of dying, a process that she says involves angels, multitudes of deceased family and friends, the spirits of deceased pets, and countless serendipitous (and miraculous) moments that are all part of a prescribed series of events. She calls this the “12 Phases of Transition™” and broadly outlines this in today’s episode. SPECIAL OFFERS FOR THE HUMAN UPGRADE LISTENERS: Julie’s giving a digital or audio copy of her books to every listener who wants one. Go to https://askjulieryan.com/ask-julie/ . Mention you heard Julie on this podcast and would like a copy. “Angelic Attendants: What Really Happens As We Transition From This Life Into The Next” or “Angel Messages For Kids” or “Angel Messages For Dogs” or “Angel Messages For Cats” WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Shield Yourself from EMFs: https://quantumupgrade.io , use code DAVE to get a two-week free trial Mattress Temperature Tech: https://www.eightsleep.com/dave , use code dave to save $250 on the Pod Pro Probiotic Eases Stress: https://www.omnibioticlife.com/DAVE , use code DAVE20 to get 20% off . Learn more:: Upgrade Spotlight: Probiotics to Power the Gut-Brain Axis – Keri Glassman, MS, RD, CDN / Omni-Biotic – #974 See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 21, 2022

Prenuvo sponsored this episode. IN THIS EPISODE OF THE HUMAN UPGRADE ™... you’ll find out about a new healthcare model that’s putting you fully in control of your health with whole-body MRI scans. Dr. Raj Attariwala, Prenuvo ’s founding radiologist, joins the show to explain how Prenuvo gives you early insight into what’s going on under your skin. His Ph.D. in Biomedical Engineering and medical degree in Nuclear Medicine and Radiology informed how he created Prenuvo’s whole-body MRI device software. Here’s what Prenuvo’s scans can do: detect nine of the 10 top cancers in stage one detect nearly 500 other medical conditions look at degeneration of the spine and body composition look at the blood in the brain and the blood vessels in the center of the brain Dave visited Prenuvo’s new Los Angeles facility right before the start of the 8th Annual Biohacking Conference in Beverly Hills to talk with Dr. Raj about Prenuvo’s innovative take on the MRI scan. With AI, Prenuvo’s bringing in quantitative reproducibility, which means you can start to see subtle changes throughout your body over time. In this conversation, you’ll learn Why it’s so important to know your health baseline instead of waiting for symptoms to present and disease to progress. The reactive medical system in the U.S. focuses on disease management after it occurs. What types of medical issues show up that may be overlooked or dismissed by your primary care doctor or other medical professionals. Existing annual checkups are relatively useless. How Prenuvo’s whole-body MRI scans can give you an “age score” for your physiology that you can track over time. This means you can make proactive, informed decisions about your own health. SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Get a $300 discount off Prenuvo’s Whole Body Scan ($2,199 instead of $2,499) . You’ll get your scan images and radiologic analysis via your smartphone app or the web. Book online: https://prenuvo.com/DAVE or b ook via phone: 1-833-PRE-NUVO (1-833-773-6886); mention code “DAVE." This discount is valid through March 10, 2023, in all Prenuvo clinics throughout the U.S. and Canada. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Business Growth With SEO: https://www.stephanspencer.com , get a FREE consultation Customized Nootropics for Your Own Neurochemistry: https://nootopia.com/dave , use code DAVE10 to get 10% off Control Blood Glucose: https://pendulumlife.com , sign up for membership to get monthly supply delivery, use code DAVE20 to save $20 on your first shipment. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 19, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™… menopause and the perimenopausal years leading up to it take the spotlight as a topic frequently requested by listeners. Great timing! It’s World Menopause Awareness Day Oct. 18 and World Menopause Awareness Month in October. More than 1 million women in the United States experience menopause each year. Still, little is known, researched or taught in medical schools about the health effects of this natural biological occurrence. Guys who love the women in their lives and younger women will get a lot of benefit out of the show, too, and come away armed with information. Note that some women go through menopause at ages earlier than 40 for various medical reasons and will want to keep listening. “I want people to stop being afraid to say menopause,” says Dr. Suzanne Gilberg-Lenz . “I think there's a lot to be said for just saying the word out loud. If we can deweaponize the term and just be talking about it like we would any other life phase, then we can be there for each other and we can also learn from each other.” Dr. Suzanne, an OBGYN board certified in integrative and holistic medicine, brings her expertise to the show to tackle this complex topic. Her “endless curiosity about the human experience” propelled her to uncover ways to ease women through menopause stages with effective tools. She looks at the science and also brings in holistic elements, including Ayurveda. For more than two decades, she’s led women through life transitions. Her new book “ Menopause Bootcamp: Optimize Your Health, Empower Your Self and Flourish as You Age ” offers practical steps and solutions that can help women navigate the many menopausal changes they may experience. Some of what you’ll learn in this extensive conversation: Ways to de-pathologize menopause—which contributes to healing ageism. What’s actually going on with your hormones during the transition to menopause and beyond. Why hormone testing isn’t all that useful. Why Menopausal Hormone Therapy (MHT and what used to be called hormone replacement therapy, or HRT)—continues to be misunderstood and controversial. How to craft specific questions to better advocate for yourself with doctors. How to recognize symptoms that can range from moderate to severe to even debilitating. How to manage symptoms that disrupt the activities of daily living and long-term health. How physical changes can drive mental health issues during this time of your life. How to take control of your symptoms and find real solutions. Dr. Suzanne’s “Menopause Bootcamp” touches on prejudice in medicine and how to break free from the societal bullshit surrounding menopause so you can get appropriate help and treatments. Calm Your Nervous System with a Weighted Blanket: : https://balooliving.com/dave , use code DAVE for a special discount Isometrics for Cardiovascular Health: https://www.zona.com , use code DAVE2022 to get $150 off the Zona Plus Brain Training with Sound & Vibration: www.braintap.com/dave to get 30% off See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 14, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... kava expert and founder of TRU KAVA, Cameron George, joins the show to share new information about the many body/mind benefits you can get from kava. TRU KAVA sets the industry standard for kava quality, safety and education. On episodes #731 and #859 , we talked about kava’s historical origins and uses, how it can be safely consumed, and how it’s extracted and processed today. You can use kava for both energy and sleep. It’s also a natural alternative to recreational alcohol and drug use. “It's like a calm, enhanced state of natural sobriety,” Cameron says. If you struggle with social anxiety, kava’s roots in community and social connection can improve your relationships, too. Today’s conversation further expands the kava discussion. “Kava is a stress-relieving nootropic,” Cameron says. “It's a natural elixir that's prepared from the roots of a plant that grows in the South Pacific. Indigenous people have used it for thousands of years and prepared this food-grade drink kind of like coffee. On the stress-relieving side, on the nootropic side, they've prepared it and used it in almost every context imaginable, weddings, funerals, spiritual ceremonies, social gatherings. It helps to open up the opportunity for human connection, but it also helps to get people focused yet relaxed and calm and in a very safe space neurologically.” Kava studies show promise for people who may be experiencing mental health issues. You’ll learn about kava’s potential to transform mental health care and its therapeutic applications for mental/trauma-related illnesses. Kava works on a psychological, emotional and physiologic level. SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: http://www.trukava.com/ , use code DAVE15 to get 15% off all products WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Science-backed, Music-driven Breathwork: Go to https://www.othership.us/dave , sign up for the app and get two weeks FREE. Isometrics for Cardiovascular Health: https://www.zona.com , use code DAVE2022 to get $150 off the Zona Plus Customized Nootropics for Your Own Neurochemistry: https://nootopia.com/dave , use code DAVE10 to get 10% off. Learn more on The Human Upgrade podcast: Hack Your Neurochemistry with Customized Nootropics – Mr. Noots & Matt Gallant – #861 See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 11, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™… you’ll learn how botanical remedies treat infectious and inflammatory diseases. You’ll get a fascinating look at how plants and microbes interact and how antibiotic resistance evolves. And you’ll meet a leader in the field of medical botany who travels to remote locations and communities around the globe seeking out modern medicines from plants. Medicinal plants make up the primary form of medicine for 70–95 percent of people living in most developing countries. At least 4 billion people are dependent on plants for medicine. Ethnobotanist Cassandra Quave, Ph.D. , is an herbarium curator and associate professor of dermatology and human health at Emory University. (She’s also a writer, speaker and podcast creator/host.) She teaches courses on medicinal plants, food, and health and her Quave Research Group leads anti-infective drug discovery research initiatives. Dr. Quave’s also the co-founder and CEO/CSO of PhytoTEK LLC. This drug-discovery company works to develop solutions from botanicals. In particular, they look at treatments of antibiotic-resistant infections like MRSA. Her battle with MRSA is personal. She was born with congenital skeletal deformities and had her leg amputated at age 3. She nearly died from a staph infection that infection required more amputation. Her early life and disability experiences shaped her life’s work with medicinal plants. She chronicles her extraordinary life, field work and scientific discovery in her book, “ The Plant Hunter: A Scientist’s Quest for Nature’s Next Medicines .” Plants are incredibly complex, and science has barely scratched the surface, Cassandra says. “Some of our best drugs for infection, cancer and pain were originally found in plants,” she says in her book. “Even though they may be produced in a factory setting now, the original chemical blueprints came from plants.” Cassandra studied pre-med in college with a double major in biology and anthropology. She couldn’t find a connection between the two fields until she journeyed to the Amazon where she studied with a local shaman/healer who relied on plants as medicine. She realized instead of going into the practice of medicine, her true path was the discovery of new medicines from nature . WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Cooler Temps for Deeper Sleep : https://www.chilisleep.com/ , use code HUMANUPGRADE20 to save 20% on the Dock Pro Sleep System Kickstart Autophagy: https://timelinenutrition.com/DAVE , use the code ASPREY10 to get 10% off any plan Capture Life Force Energy : https://leelaq.com , use discount code DAVE10 to get 10% off sitewide See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 8, 2022

Othership sponsored this episode. IN THIS EPISODE OF THE HUMAN UPGRADE™ …you’re listening to a new Upgrade Spotlight series. Once a month, these shorter episodes feature guests who get right into useful information in a Q&A style. You’ll find out how to improve your energy and upgrade your performance. You’ll also get the latest knowledge about powerful tools and technologies that allow you to change your biology and the environment around you. Introducing Othership ! During this Upgrade Spotlight, you’ll find out how Othership’s breathwork app teaches you ways to manage your most prevalent stressors. Things like tension, anxiety, overwhelm, processing emotions, irritability, trouble sleeping, low energy, nervous system dysregulation or mental health issues. When you begin to regularly incorporate breathwork into your life, you notice and feel the emotional, mental and physical differences right away. Breathwork is a visceral, physiological shift that you can reach in under five minutes. It’s the perfect primer to bring you into a meditative state, with even more physical benefits. BONUS! You can experience this shift by following along with the live demo in this episode led by Othership co-founder, Robbie Bent. (Make sure you’re not driving!) Robbie joins the show to talk about the power of adding a breathwork practice to your everyday routine. If you’ve tried meditation and it wasn’t your thing, or you struggle with consistent mindfulness, the Othership app gives you lots of options to find what fits. You can access more than 500 guided breathwork sessions within three styles: up, down and explorer. Othership combines breathing techniques and guided meditations created by psychotherapists, wellness practitioners, hypnotherapists, artists and DJ’s, spiritual teachers and life coaches. The sessions are music-driven, science-backed and curated by expert facilitators. The Othership app helps you build and sustain a new mindfulness routine – all through the power of your breath. Whether you have time to practice for one minute, or 60, you’ll be able to shift your state in a session style that works best for you, such as: Deep breathing + breathwork Guided meditation Affirmations + visualizations Sound healing Hypnosis Somatic release therapy Vocal toning Intention setting Self-massage + stretching Movement + dance Mind-body connection Mindful walking + working SPECIAL OFFER FOR LISTENERS OF THE HUMAN UPGRADE: Visit https://www.othership.us/partnerships/dave-asprey and get a two-week FREE app trial. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 7, 2022

( BrainTap ® sponsored this episode.) IN THIS EPISODE OF THE HUMAN UPGRADE ™… brain expert Patrick Porter, Ph.D. , joins Dave at the 8th Annual Biohacking Conference in Beverly Hills to talk about training your brain. Dr. Porter pioneered the use of brainwave entrainment with a technology-enhanced meditation device called BrainTap. Whether you’re a newbie, a hard-core devotee or somewhere in the middle of your biohacking journey, you already focus on body exercise and nutrition. You probably manage your stress and mental health, too. It’s all training of some sort, which is where BrainTap comes in. It’s a specific kind of training for your brain. New discoveries in science reveal that you can form new neurons in your brain, called neurogenesis. Your brain state isn’t fixed! And then there’s neuroplasticity, a process of adaptive structural and functional changes to the brain that involves connections to your nervous system. BrainTap’s unique technology uses light, sound and vibration to train and regulate your brain for relaxation, sleep, performance, weight loss, aging and more. To get to a higher personal frequency on the regular, you want to achieve coherence. Since Dr. Porter specializes in the science of calming the brain, you’ll find out how you can manage your physiological and mental health in today’s super stressed-out world. You’ll also learn how impact remote work, remote learning and pandemic isolation impacted brain health and memory. This conversation gets into some of BrainTap’s exciting research with aging populations and elite athletes. too. SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: https://braintap.com/dave WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Isometrics for Cardiovascular Health: https://www.zona.com , use code DAVE2022 to get $150 off the Zona Plus Mattress Temperature Tech: https://www.eightsleep.com/dave , use code dave to save $250 on the Pod Pro A Cleaner Nicotine Alternative : https://lucy.co , use code DAVE20 for 20% off your first order of pouches, gums or lozenges See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Oct 4, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™… you’ll learn how you can make smarter food choices to support your metabolic energy and upgrade your brain. You’ll also find out some new things about body fat. For example, did you know that it’s a complex organ that communicates throughout your entire body system? You’ll get tips on fat loss essentials and how to use them to your advantage. Today’s guest, Shawn Stevenson, hosts a popular podcast called The Model Health Show . He’s a nutritionist, researcher and bestselling author with education and experience in business, biology, and nutritional science. Shawn’s been in the health and wellness space and doing clinical work as a nutritionist for nearly two decades. He’s known for his ability to keep learning and evolving his approach with deep research into the science of human health. He’s all about improving human performance and energy with science-backed basics like food in his “ Eat Smarter ” book and sleep in his “ Sleep Smarter “ book. This episode gets right into food choices you can make—and why they work—to stoke your metabolic energy. Topics like: How people can better understand the process of fat loss. How the misconstrued science of calories contributes to how much people struggle with their diets. What metabolic switches are, what do they do, and why it’s important for you to know how to turn them on and off. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Custom Silver for Health & Healing: https://tru47.com/dave , use code DAVE20 to get 20% off for a limited time Customized Nootropics for Your Own Neurochemistry: https://nootopia.com/dave , use code DAVE10 to get 10% off Business Growth With SEO: https://www.stephanspencer.com , get a FREE consultation See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 30, 2022

In this Episode of The Human Upgrade™...​ Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month. • Saving your poop may save your microbiome • Insults trigger a mini slap in the face • Young cerebral spinal fluid supports memory in aging brains • The distinct role your nose plays in your friendships EPISODE SPONSOR: Get Fit in Five Minutes: Go to https://www.carolbike.com . Use code HumanUpgrade to get 2 years of free membership (a total savings of $360). CAROL Bike also offers a 100-day home trial of the CAROL Bike 2.0. Learn more: How to Hack Your Cardio Workout – Ulrich Dempfle – #978 . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 29, 2022

BodyBio sponsored this podcast. IN THIS EPISODE OF THE HUMAN UPGRADE ™… you’ll learn how butyrate and phospholipids keep your gut, cells and brain performing at their best. You’ll find out how your mucosal barrier defends against pathogens in your gut microbiome. You’ll also learn about discoveries in the field of cell membrane medicine. This focus determines how your body functions now and also how you age. Jessica Kane Berman joins the show to share new information and interesting science about cellular health from the perspective of BodyBio , the company founded by her grandfather, Ed Kane, an inventor, health explorer and early biohacker. He went looking for answers to his own health issues in the 1980s and got deep into the science of fatty acid research and cell membrane medicine through blood testing. BodyBio sticks to a very specific group of products, most notably butyrate and a phospholipid complex of phosphatidylcholine . Jess explains how true liposomal phosphatidylcholine and phospholipids get through to the cells to help rebuild that membrane. Here’s a few good things butyrate does in your gut: Helps maintain the thickness of the mucosal barrier—keeps the good in and the bad out Helps the expression of tight junctions and strengthens the gut wall Expresses MUC2: this produces mucus, which thickens your mucous lining Regulates T-Cells and helps lower cytokine release Increases microbiome diversity Anti-inflammatory properties help improve intestinal barrier function and mucosal immunity Butyrate goes way beyond the gut to influence bone mass and density, asthma and allergies, histamine intolerance, body detoxification, inflammatory brain pathways, and mitochondrial function. Butyrate also can alter gene expression, protect against cancer, and regulate the body’s immune system. SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: https://bodybio.com/dave , use code DAVE25 to get 25% off WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Cooler Temps for Deeper Sleep : https://www.chilisleep.com/ , use code HUMANUPGRADE20 to save 20% on the Dock Pro Sleep System Isometrics for Cardiovascular Health : https://www.zona.com , use code DAVE2022 to get $150 off the Zona Plus Shield Yourself from EMFs : https://quantumupgrade.io , use code DAVE to get a two-week free trial See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 27, 2022

In this Episode of The Human Upgrade™...​ Dave talks about what could be causing brain fog with a podcast guest in this impromptu intervention. Keri Glassman, MS, RD, CDN, recently spoke about gut health as the expert for Omni-Biotic probiotics. During the interview, she was searching for a word and got frustrated she couldn’t grasp it quickly. This intervention looks at the potential culprits responsible for Keri’s brain fog and memory hiccups: Thyroid Hormones, such as testosterone and DHEA Perimenopause Mast cell-mediated inflammation Cortisol & stress ADHD Mold toxins Mercury & lead Keri is a registered dietitian, certified nutritionist, healthy cooking expert and author of four books. She also founded Nutritious Life , a lifestyle and media company and Nutritious Life Studio , an online education platform focused on nutrition, coaching, and business. Find tips and resources on the episode webpage . Note: The "Interventions With Dave” recommendations are designed to help you upgrade yourself and your biology so you can perform better at everything you do. They are not, however, a substitute for advice or treatment by a trained medical professional that may be needed for specific health conditions, illness or injury. WE APPRECIATE OUR PARTNERS, CHECK THEM OUT! Nature’s Nootropic: https://trukava.com , use code DAVE15 to get 15% off Business Growth With SEO: https://www.stephanspencer.com , get a FREE consultation Mattress Temperature Tech: https://www.eightsleep.com/dave , use code dave to save $250 on the Pod Pro See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 22, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™…a legacy upgrade conversation with Dr. Joe Dispenza explores how you can change from the inside out through a combination of neuroscience, epigenetics, quantum physics—and even a divine source. “I teach people the science of changing their mind and what it is to truly transform,” he says. He shows people how to rewire their brains and recondition their bodies to make lasting changes by way of science, energy and mysticism. His background and expertise include training in neuroscience, neurology, cellular biology, brain function and chemistry, memory formation, and aging and longevity. From healing illness to evolving consciousness, Dr. Dispenza examines how to connect with the divine and bridges the mystical with science. “It's really important to have science demystify that process,” he says. Why? Because science is a contemporary language that offers you explanations, helps you understand the how and why, and assigns clear meaning. “Here's what I know,” Dr. Dispenza says. “We have evidence that you can make your brain work better. As you can prove also, we have evidence that you can make your heart work better. We have evidence, you can strengthen your immune system. We have evidence, you can change your gene expression in four days. We have evidence, you can lengthen your life from meditation, just by lengthening your telomeres and changing your state. We have evidence in the scientific world that people actually can transform.” Listen on to learn about the power of inner work, elevated emotions and human connection. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! A Cleaner Nicotine Alternative : https://lucy.co , use code DAVE20 for 20% off your first order of pouches, gums or lozenges Customized Nootropics for Your Own Neurochemistry: https://nootopia.com/dave , use code DAVE10 to get 10% off. Learn more on The Human Upgrade podcast: Hack Your Neurochemistry with Customized Nootropics – Mr. Noots & Matt Gallant – #861 Probiotic Eases Stress: https://www.omnibioticlife.com/DAVE , use code DAVE20 to get 20% off . Learn more on The Human Upgrade podcast: Upgrade Spotlight: Probiotics to Power the Gut-Brain Axis – Keri Glassman, MS, RD, CDN / Omni-Biotic – #974 See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 20, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™… you’ll learn about a “6 Phase Meditation” approach that absolutely everyone can do—and benefit from!—no exceptions. This custom-designed meditation sequence gets you into a peak state in just a few minutes. No boredom, special breathing, or clearing your mind required. You’ll find out how to make meditation work for you and how you can use intuition as one of your greatest strengths. Episode guest Vishen Lakhiani took up meditation at age 26 as a way to cope with the stress of working for a startup in Silicon Valley. That decision changed his life so dramatically that within two years he quit to pursue meditation, other tools of personal development, and then spread awareness and education to people around the world. He’s taught his signature 6-phase meditation style to world-class athletes, professional entertainers and high-performers in all types of business. He also founded Mindvalley, an international learning platform. Vishen’s newest book, “ THE 6 PHASE MEDITATION METHOD: The Proven Technique to Supercharge Your Mind, Manifest Your Goals and Make Magic in Minutes a Day ,” outlines a series of science-backed mental exercises for accomplishing your goals. It condenses the wisdom of nearly 1,000 neuroscientists, monks, yogis, and meditation experts into a hyper-efficient programming script that you can run through your mind any time of day. Unlike traditional meditation that encourages a calm and serene environment, the 6 Phase Meditation Method can be done from anywhere—your bed, your office or even on your next flight. “It's six different practices that you layer on that put you in a hyper-optimized state,” Vishen says. You’ll get a lot out of this fascinating conversation that gets into realms of spirituality, psilocybin, perceptual diversity, physics, brain waves, and altered states. SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS : Mindvalley.com/books/6phase WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Shield Yourself from EMFs: https://quantumupgrade.io , use code DAVE to get a two-week free trial Structure Water Molecules; Achieve Body/Brain Coherence: https://analemma-water.com , use code DAVE10 for 10% off Isometrics for Cardiovascular Health : https://www.zona.com , use code DAVE2022 to get $150 off the Zona Plus See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 15, 2022

CAROL Bike sponsored this podcast. IN THIS EPISODE OF THE HUMAN UPGRADE ™ … you’ll learn about new research that’s pinpointing the most effective cardio workouts. You’ll find out that you can do a cardio workout in just 15 minutes a week and still increase your cardiovascular fitness. You’ll also get an introduction to the new CAROL Bike 2.0 and its upgraded great features. Ulrich Dempfle, MBA, Chief Product Officer, CEO and co-founder of CAROL Bike, returns to the podcast with exciting new research results. CAROL’s REHIT (Reduced Exertion HIIT) workout retained all its effectiveness yet cut its time nearly in half—from 8 minutes and 40 seconds to five minutes. CAROL Bike continues to innovate fitness and prove that more or longer sprints aren’t better. “What matters is that you sprint at your personalized maximum intensity, switching from zero to max in a fraction of a second,” Ulrich explains. An investment of only 5 minutes, 3 times a week means you can reap powerful cardiovascular benefits, even gain strength, and get on with your other biohacks. SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://www.carolbike.com . Use code HumanUpgrade to get 2 years of free membership (a total savings of $360). CAROL Bike also offers a 100-day home trial of the CAROL Bike 2.0. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Harness Cold to Improve Health & Performance : https://www.cryobuilt.com Sleep Better on Natural Memory Foam: https://myessentia.com , use code DAVEVIP to get an exclusive discount. Learn more on The Human Upgrade podcast: Mattress Smarts 101 for High-Performance Sleep – Jack Dell’Accio – #875 Customized Nootropics for Your Own Neurochemistry: https://nootopia.com/dave , use code DAVE10 to get 10% off. Learn more on The Human Upgrade podcast: Hack Your Neurochemistry with Customized Nootropics – Mr. Noots & Matt Gallant – #861 See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 13, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™ … you’ll learn to define what’s really “normal” when it comes to your health. You’ll explore how today’s culture stresses the body, burdens the immune system, and undermines emotional balance. And why Western medicine often fails to treat the whole person. This conversation covers an investigation into the causes of illness, a critique of how our society breeds disease, and offers a pathway to health and healing. One of the surprising things you’ll learn has to do with authenticity. “The loss of authenticity is one of the major impacts of trauma,” says renowned Canadian speaker and bestselling author, Dr. Gabor Maté . “It's also a major cause of physical and mental illness.” Dr. Maté is highly sought after for his expertise on topics like addiction, stress, trauma, and childhood development. He spent two decades in family practice and palliative care. He also worked for over a decade in Vancouver’s Downtown East Side (Canada) with patients challenged by drug addiction and mental illness. In his newest book, “The Myth of Normal: Trauma, Illness, & Healing in a Toxic Culture,” he pushes back on the prevailing understanding of “normal” because it neglects the roles that trauma and stress—and the pressures of modern-day living—exert on our bodies and our minds at the expense of good health. “If you're suffering, don't accept it as normal, but ask what's going on here?” Dr. Maté says. “Let the suffering instruct you that there's something going on; that what you think is normal is actually not healthy or natural for you.” WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Tasty Keto Bread & Chips : https://www.uprisingfood.com/DAVE , use code DAVE to get $10 off the starter bundle A Cleaner Nicotine Alternative : https://lucy.co , use code DAVE20 for 20% off your first order of pouches, gums or lozenges Control Blood Glucose : https://pendulumlife.com , sign up for membership to get monthly supply delivery, use code DAVE20 to save $20 on your first shipment See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 8, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... you’ll learn that while yes, testosterone fuels energy and performance, it’s not the be-all and end-all solution for men’s health woes. A systems biology approach considers many other aspects and provides a broader perspective about what’s going on with you. This conversation features board-certified urologist Tracy Gapin, M.D. , one of the 8th Annual Biohacking Conference keynote speakers . He’ll be on the main stage in Beverly Hills in September. He joins this special preview episode to discuss new ways for men to improve their health and performance. He uses epigenetic coaching, hormones, peptide therapy, biometric monitoring, and unique nutrition and lifestyle interventions. “Testosterone levels over the last 30 years are down by about 30 percent,” Dr. Tracy says. “Free testosterone, which is the bioavailable, active hormone testosterone is actually down over 45%. This is really important. We're not just talking about sex and muscle, we're talking about a man's life and cardiovascular health and cognitive function. The culprit can be debated, but without question, one of the biggest ones in my mind is endocrine disruptors. Toxins, chemicals in our environment that are clearly crushing men's health, clearly crushing testosterone. It's the food we eat, it's the water we drink, it's the personal care products. It's ubiquitous, it's almost everywhere and it's getting worse.” In his book, “ Male 2.0™: Cracking the Code to Limitless Health and Vitality ,” he says medical school, residency training and even a two-decade career in urology and surgery specialties didn’t teach him how to get to root causes of men’s issues and solve them. He had a health crash of his own at 42. Since neither he nor his doctor had good answers, he went on a quest of discovery and change. He founded the Gapin Institute for High Performance Medicine and created the proprietary N1 Performance Health Program to go beyond conventional options. This conversation goes even further into what creates epigenetic signals that affect the function and expression of your genes. You’ll learn, too, that your mindset, stress and environment—and how you do or don’t control those things—have everything to do with your energy and focus. If you’re aiming for higher performance, Dr. Tracy suggests a trifecta that makes sleep a priority, builds resilience to stress, and creates consistent behaviors with intention. More about Dr. Tracy Gapin: He’s a member of the American Academy of Anti-Aging, the Age Management Medical Group, and the International Peptide Society. He spent almost 20 years at a urology practice in Sarasota, Fla., where he specialized in robotic surgery, minimally invasive treatment for prostate cancer, and men’s health. SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: TEXT “ HEALTH ” to 2 6 7 8 6 to get three bonus gifts. *** WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Vascular System Protection: https://arterosil.com/DAVE/ , save up to 45% on a 3-pack to protect your blood vessels from vulnerable plaque Mattress Temperature Tech: https://www.eightsleep.com/dave , use code dave to save $250 on the Pod Pro Kickstart Autophagy: https://timelinenutrition.com/DAVE , use the code ASPREY10 to get 10% off any plan See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 6, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... you’ll learn about female hormones: what they are, what they do and what disrupts them. You’ll learn about the hormonal shifts that happen at different ages and life stages and get tips on how to balance hormones and make them work for you, not against you. This conversation features Anna Cabeca, D.O. , one of the 8th Annual Biohacking Conference keynote speakers . She’ll be on the main stage in Beverly Hills in September. Dr. Anna is a Doctor of Osteopathy who’s triple-board certified in gynecology and obstetrics, integrative medicine, and anti-aging and regenerative medicine. She has additional certifications in functional medicine, sexual health, and bioidentical hormone replacement therapy. She joins this special preview episode to talk about female hormones. It’s her particular area of expertise and one of The Human Upgrade’s all-time Top 10 podcast topics. Today’s hormone discussion includes: How hormone disruptors go beyond stress to mold, and product and environmental toxins How estrogen levels change over time What’s going on with progesterone, pregnenolone and DHEA, too What happens to hormones during perimenopause and menopause What’s causing brain fog What to know about bioidentical hormones How detoxing affects hormones How to keep your vaginal microbiome balanced How “food as medicine” helps balance hormones How hormones influence longevity And much more! For the past 20 years, Dr. Anna's educated and helped women with their hormones through her private practice, books, online videos and articles. Learn more about her work with women’s hormone health: “ MenuPause: Five Unique Eating Plans to Break Through Your Weight Loss Plateau and Improve Mood, Sleep, and Hot Flashes ” “The Hormone Fix: Burn Fat Naturally, Boost Energy, and Stop Hot Flashes the Keto-Green™️ Way” “Keto-Green™️ 16” WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Customized Nootropics for Your Own Neurochemistry: https://nootopia.com/dave , use code DAVE10 to get 10% off Track Your Blood Glucose to Improve Your Metabolic Health: https://levels.link/ASPREY to learn more Business Growth With SEO: https://www.stephanspencer.com , get a FREE consultation See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 3, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE™... …you’re listening to a new Upgrade Spotlight episode with Omni-Biotic . You're going to find out how probiotics can do more than keep your gut microbiome in order—specific strains can help you manage your stress and regulate your body’s detox system. The beneficial bacteria in your gut support essential processes in the body, such as digestion and absorption, immune function, detoxification, and brain function. But did you know that 80% of the immune system lives in the gut and 95% of serotonin is produced in the gut? That’s a lot for the gut to do! Keri Glassman, MS, RD, CDN , joins the show to talk about one of her favorite topics—the gut-brain axis. Keri’s a registered dietitian, certified nutritionist, healthy cooking expert and author of four books. She also founded Nutritious Life , a lifestyle and media company and Nutritious Life Studio , an online education platform focused on nutrition, coaching, and business. In this conversation, you’ll learn how Omni-Biotic’s unique delivery mechanism and multi-species, multi-strain formulations work together to upgrade your gut AND your brain. The gut-brain access goes two ways, Keri explains. “Your brain is affecting your gut. Your gut is affecting your brain—and from everything. That's why it's so incredibly important to maintain that healthy microbiome and to have a healthy balance of good [bacteria].” To target the gut-brain axis, Omni-Biotic developed special formulations called psychobiotics: one for detox, the other for stress. Then they put them to the test in clinical studies . Hetox contains eight beneficial bacterial strains. Clinical studies show improvements in liver function, cardiometabolic markers and inflammation markers related to liver health. Clinical studies show that Stress Release supports digestion and the gut flora during times of stress, reduces intestinal inflammation, increases emotional balance, cognition, and mood. More to Know About Omni-Biotic Probiotics: Omni-Biotic also tests its probiotics in an artificial GI simulator against other top probiotic brands in the U.S. market. It ensures that 83% of its probiotics arrive alive and active in the intestines. In comparison, the probiotic survival rate of other brands averages 7%. The bacterial strains in Omni-Biotic are freeze-dried to make them more shelf-stable and the powder contains specific prebiotic nutrients. These prebiotic nutrients serve as the food source for the probiotic bacteria. SPECIAL OFFER FOR LISTENERS OF THE HUMAN UPGRADE: Visit https://www.omnibioticlife.com and use code Dave20 to get 20% off WE APPRECIATE OUR PARTNER, HIGHER DOSE. CHECK THEM OUT! Experience the High Life with Infrared Therapy: https://higherdose.com , use code HUMAN15 for 15% off See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Sep 2, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... … you’ll learn how to recognize your own sh*t and be a better partner in relationships. Want a sustainable partnership? Communicate and apologize; fight without fighting; identify codependent behavior (your own); and manage jealousy (also your own). This conversation gets into how you can let go of unrealistic ideals of how you think love and relationships should be and live fully in the present. You’ll also get tips on how to be emotionally responsible to people you love every day. Guest John Kim, a licensed marriage and family therapist, as well as a life coach, cracks his life into two big pieces… split on either side of what he calls “the great divide” of his own divorce several years ago. He did the whole “get a tattoo and a Harley” thing to find his way. He also combined what he learned in therapy school with life coaching and technology to be mobile and create online communities. He became known as an unconventional therapist, seeing clients at coffee shops, on hikes, or in a CrossFit box. He’s built a devoted following of fans who love the frank and authentic insights that he—as “The Angry Therapist”—freely shares on social media. TikTok’s his jam, with over 450K people tuning in for his “shot glass” bits of life wisdom. In his newest book, written with his romantic partner and fellow therapist Vanessa Bennett , John takes a different (honest, humorous, raw) approach by dissecting his own relationship dynamic to bring clarity to yours. Each part of “ IT’S NOT ME, IT’S YOU: Break the Blame Cycle, Relationship Better ” gives you questions to ask yourself and practices to do. It’s a book that pushes you into doing and putting your newfound knowledge to IRL use. Here’s a sneak peek at a few of the Love Lessons (In a Shot Glass) you’ll find in “ It’s Not Me, It’s You .” Love is not a battlefield. Your head is. If someone is unsure about you, it’s never worth the investment. Hold love, don’t grab it. Don’t stop believing (be Journey). Love is what teaches us how to live. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Infrared Sauna Benefits: https://www.sunlighten.com , use code DAVE to save up to $600 Custom Silver for Health & Healing: https://tru47.com/dave , use code DAVE20 to get 20% off for a limited time Repair Oxidative Stress Damage: https://eng3corp.com/DAVE/ , learn even more by listening to The Anti-Aging Science Behind the NanoVi Device – Rowena Gates & Hans Eng – #416 See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 30, 2022

In this Episode of The Human Upgrade™...​ … Dave tackles multiple issues with former Upgrade Collective member Nancy Pellegrino so she can better manage psoriasis, gut health and anxiety. Nancy’s been biohacking for a few years but can’t seem to land on the right combination. She does the hacks, uses the gadgets and tech, and takes the products and supplements. Instead of feeling better, she’s feeling overwhelmed with information. She talks with Dave to sort it out, focusing on skin and gut health. Now in her mid-50s, Nancy’s post-menopausal and does bio-identical hormone replacement therapy. She experienced—and beat!—colorectal cancer in 2017. She routinely uses her Sunlighten sauna, an ozone machine and a ChiliSleep cooling mattress pad. Her busy life as a teacher and mom to three daughters makes it hard for her to meditate and relax. She’s looking to ease some body distress, focus on solutions and find benefit in biohacks that work for her particular symptoms. She hasn’t found a resolution to chronic psoriasis. Despite following the Bulletproof Diet, drinking Bulletproof Coffee and regularly intermittent fasting, she continues to have unexplained digestive issues. She wakes up in the night with feelings of anxiety. Note: The "Interventions With Dave” recommendations are designed to help you upgrade yourself and your biology so you can perform better at everything you do. They are not, however, a substitute for advice or treatment by a trained medical professional that may be needed for specific health conditions, illness or injury. Hacking Deep Sleep #957 Hacking Mast Cells, Hormones & Mold #949 Hacking Your Biohacks for Better Sleep, Fitness & Weight Control #939 Hacking Weight Loss Resistance #930 Hacking Thyroid, Autoimmunity & Aging #918 Hacking Inflammation #915 Hacking Your Gut Microbiome #908 Hacking Menopausal Weight Gain #904 Hacking Eyesight #895 WE APPRECIATE OUR PARTNERS, CHECK THEM OUT! Control Blood Glucose: https://pendulumlife.com , sign up for membership to get monthly supply delivery, use code DAVE20 to save $20 on your first shipment Isometrics for Cardiovascular Health : https://www.zona.com , use code DAVE2022 to get $150 off the Zona Plus Capture Life Force Energy: https://leelaq.com , use discount code DAVE10 to get 10% off sitewide See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 26, 2022

In this Episode of The Human Upgrade™...​ Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month. • Gut bacteria convert vitamin A to retinoic acid • Low-carb diets contribute to depression • Lifestyle affects cognitive health more than age • More bad news about America’s obesity epidemic EPISODE SPONSOR: Sleep Better on Natural Memory Foam: https://myessentia.com , use code DAVEVIP to get an exclusive discount. Learn more: Mattress Smarts 101 for High-Performance Sleep – Jack Dell’Accio – #875 . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 25, 2022

Dave Asprey partners with Nillion as an advisor and investor. IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... … you’ll learn about the frontier of web3 and privacy and what happens to your private data (both on blockchains and in general). You’ll also find out how and why the future moves away from transactions (blockchain) and into computations (multi-party computation). Think about where you store your identity and your deepest digital secrets. The current solutions aren’t great — in web2, the Big Tech 'old guard' has been quietly storing and monetizing your data for over a decade, and in web3, blockchains aren't designed to handle private data. A new algorithm, Nillion , inspired Conrad Whelan (the Founding Engineer of Uber ) to come out of early retirement and do something about this. This conversation looks at the data you unassumingly give away freely, and how it’s captured, held and used/computed on without your consent by large companies and other parties. Conrad believes in a future where your sensitive data and digital secrets can be fully controlled by you (and you alone) using web3 technology. This means you’d be the final gatekeeper of your data with the power to authenticate, authorize and use it as you see fit. Conrad’s building that future as Nillion’s Founding Chief Technology Officer. His background includes electrical and computer engineering. He worked in the fields of computational electromagnetics before joining Uber as Founding Engineer . He’s developed, tested, deployed and architected software projects at all levels of the software stack as both an engineer and an engineering manager. In 2016, he retired to focus his efforts on philanthropy and personal passion projects while keeping an eye on the tech world. The promise and potential global impact of Nillion enticed him out of retirement and into the company’s CTO role. What Conrad is building at Nillion aims to: render both computational encryption and centralized storage of private data obsolete; fundamentally change the way private data is stored and processed; offer alternative non-blockchain ways of using decentralized nodes; serve as a ‘Meta Layer’ that provides new and additional functionality to existing blockchains; and enable a host of new real-world applications on its native public network (the Nillion Network). Whatever your level of tech understanding, this discussion offers critical insights about the next big move in decentralized computing and data privacy. Find more info in the show notes on this episode's webpage: https://daveasprey.com/conrad-whelan-971/ WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Capture Life Force Energy: https://leelaq.com , use discount code DAVE10 to get 10% off sitewide Business Growth With SEO: https://www.stephanspencer.com , get a FREE consultation A Cleaner Nicotine Alternative: https://lucy.co , use code DAVE20 for 20% off your first order See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 24, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... … you’ll learn why regenerative methods for taking care of soil and raising animals provide a solution that creates food sovereignty, improves human health, and helps reverse climate change. Previous episodes of this podcast featured regenerative farming and soil conservation topics. Dave Asprey keeps the conversation going because when you know what’s happening and what companies are doing about this problem, you can be informed and take action to support regeneration efforts in your own way. Robby Sansom, co-founder and CEO of Force of Nature , joins the show to talk about the new developments igniting real change. His roots run deep in the natural food community, caring for soil and caring for animals. He spent much of the last decade studying regenerative agriculture at ranches all over the world. Through this education, he helped found the Austin, Texas-based regeneratively sourced meat company, Force of Nature . The company’s building brand new global supply chains of grass-fed and regeneratively managed livestock. Force of Nature works in partnership with land stewards, ranchers and farmers committed to creating a positive return on the planet. There’s an undeniable sense of urgency about the state of soil and its ability to provide enough food for a growing population. Over more than a hundred years of conventional farming and ranching depleted land and disrupted natural ecosystems. These harms (have and continue to) adversely affect animal and human health. Force of Nature focuses on repair and regeneration—in their own operations and by educating farmers and ranchers from homesteaders to big corporations. In spring 2022, Force of Nature hosted a What Good Shall I Do? event about learning and leading with regenerative intent. This educational forum hosted several dozen speakers from soil scientists to leaders in the regenerative movement to individual farmers and ranchers. By providing information, resources and tools, conventional farmers and ranchers can make the switch to regenerative methods. And farmers and ranchers who already use regenerative methods can improve and have even more impact. You can get involved, too! In this episode, Robby talks about the true cost of meat and gives tips on what to look for in your own local grocery and how you can support regenerative agriculture and ranching in a way that aligns with your own values. Every small step toward change contributes to a larger movement. SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Visit https://forceofnature.com and use code dave10 to get 10% off your first order. DON’T MISS THIS! Force of Nature will be providing meat at select 8th Annual Biohacking Conference events coming up in September. Get your ticket. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 24, 2022

Uprising Food sponsored this podcast. Dave Asprey partners with Uprising Food as an advisor and investor. IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... … you’ll learn about bread that’s better for your body—and the important role of prebiotics and fiber in that equation. You’ll also find out about the science that supports new ways of creating bread products—what works and why it works. And you’ll get a look further into the food system and how to adopt solutions with real benefits for your energy and lifestyle. A 5+ year biohacker, intermittent faster, and cyclical keto devotee joins the show to talk about innovations in bread as you know it . William Schumacher, co-founder and CEO of Uprising Food—aka—”The Loafer and Chief”— traded in corporate life as a former Procter and Gamble marketer to sift through the disinformation to de-villainize bread and create products that taste good and work in synergy with your body. With all the gluten-free and alternative breads out there competing for attention, what made Uprising stand out to Dave Asprey? Simple. Uprising took action to: tackle the foundational things that give people disproportionate bang for their buck when they eat the products day in day out. figure out what’s NOT in the product. Most products are loaded with things that are doing damage and there’s a big-time cost. eliminate gluten and other inflammatory ingredients. choose ingredients that would produce a tasty, functional product and work in the gut to enable inside out transformation. partner with artisanal bakers willing to experiment with baking methods and ingredients. The star ingredient? Psyllium. In this conversation, you’ll get all the details on prebiotic fiber and the benefits of activated psyllium, a bio-active polysaccharide. Research done at Wright State University Microbiome Lab compared Uprising Food bread with traditional bread. Early results show that Uprising’s prebiotic bread makes nice with gut microbiota. Curious about bread again? Check out the Uprising Food “ Toast Cleanse ,” affectionately known as “72 hours to digestive deliverance.” This 3-day protocol includes super toast combinations and levels of bread eating designed to overhaul your microbiome. SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: www.uprisingfood.com/DAVE , use code DAVE to get $10 off the starter bundle Excited about bread that’s better for you? Learn how you can invest in Uprising Food here . WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Structure Water Molecules; Achieve Body/Brain Coherence: https://analemma-water.com , use code DAVE10 for 10% off Experience the High Life with Infrared Therapy: https://higherdose.com , use code HUMAN10 for 10% off Mattress Temperature Tech: https://www.eightsleep.com/dave , use code dave to save $250 on the Pod Pro See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 18, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... … you’ll learn about shamanism, “spiritual minimalism” and how traditional healing arts connect so profoundly to the natural world. This conversation also explores distinct themes of consciousness, the soul, and deep respect for plant medicine and Ayahuasca ceremony. The guest, Shaman Jorge Hachumak, is a Peruvian of Spanish descent who’s made a winding journey into shamanism as a healer. After receiving a European education, he became a practitioner of Chinese Qigong in old Lima’s (Peru) China Town. After a successful career in tai chi competition, he worked with elderly patients in hospitals in Northern Peru. During this time, he was taken under the wing of native shamans, witches and herbalists who spent years teaching him the ancient healings. He learned ancient Peruvian medicine arts (not from the Incas, but from the North Coast and the Northern jungle of the Amazon). He now moves seamlessly between perspectives, having one foot firmly in the rational, scientific world and another in the spirit world. “The ancient healing arts are deep and expansive—you never stop learning, and what you learn in a lifetime will always be a small fraction of what is available to learn,” he says in his new book, “Journeying Through the Invisible: The Craft of Healing With, and Beyond, Sacred Plants, as Told by a Peruvian Medicine Man.” “I want to offer a larger picture of the Medicine Craft and to create appreciation for other important aspects that are endangered or still not well-known.” This larger picture includes influences from science, history, religion and the natural environment. Shaman Hachumak looks at consciousness as two states that lead to both deep understanding of the healing arts and deep self-reflection: Suffering Consciousness keeps us stuck in our negative ways Soul Consciousness is awakened during a ceremony or spiritual moment. Your entire being awakens, and you are shown the way to live according to the dictates of your conscience and the teachings of the spirits. He also uses his knowledge and experience to broaden people’s understanding of Ayahuasca as a powerful plant medicine. He works to protect Ayahuasca and the traditional ceremony from misuse and exploitation. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Probiotic Eases Stress: https://www.omnibioticlife.com/DAVE , use code DAVE20 to get 20% off Vascular System Protection: https://arterosil.com/DAVE/ , save up to 45% a 3-pack to protect your blood vessels from vulnerable plaque Hydrate with Electrolytes: https://DrinkLMNT.com/DAVE , get a FREE LMNT Sample Pack with 8 single-serving packets for the cost of shipping ($5 for U.S. customers) See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 16, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... … you’ll find out about the relevance of shamanism in a modern world and why high performers are turning toward shamanic practices to get ahead. The show’s guest, Manvir Singh, Ph.D. , is an anthropologist at the Institute for Advanced Study in Toulouse, France. He studies universal or near-universal cultural practices, including music, shamanism, and witchcraft. For the past seven years, he’s conducted ethnographic fieldwork in Indonesia. He recently wrote an article in WIRED magazine titled, “ The Shamanification of the Tech CEO ,” noting some curious parallels. “Silicon Valley austerity continues to grow more extreme. By 2020 intermittent fasting was no longer enough, and dopamine fasting—an abstention not just from food but from any form of stimulation, including music, eye contact, and playing Magic: The Gathering —had taken off. These self-denial fads are often touted as biohacking innovations. Yet as an anthropologist who has studied austerity in some of the most remote regions of the world, I see them as part of a larger pattern: the self-shamanification of tech CEOs.” “Analyzing an old dataset of 43 nonindustrial societies, I found that shamans in 81 percent of the societies observed prohibitions on food, sex, or social contact. Given that these data were collated from reports by travelers and anthropologists, they are probably an underestimate. Silicon Valley deprivation, it turns out, is less a strange, new development and more the most recent manifestation of a ubiquitous shamanic practice.” This conversation gets into: shamanism in general the cultural significance of shamans how shamanic practices have made their way into modern culture why humans think they need shamans—or similar “magic” or “other” beings More about Manvir Singh, Ph.D.: Manvir earned a Ph.D. in Human Evolutionary Biology at Harvard University and a Sc.B. with Honors in Human Biology: Evolution, Environment, & Ecosystems at Brown University. He’s received multiple awards, honors, grants and fellowships—from Fulbright Scholarship to visiting scholar and research fellow. He’s written more than a dozen peer-reviewed journal articles and more than a dozen articles for general audiences. He gives talks domestically and internationally on the topic of shamans. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Control Blood Glucose: https://pendulumlife.com , sign up for membership to get monthly supply delivery, use code DAVE20 to save $20 on your first shipment Increase BDNF and Support Neurogenesis: Go to https://nootopia.com/davegenius , use code DAVE10 to get an extra 10% off Isometrics for Cardiovascular Health : https://www.zona.com , use code DAVE2022 to get $150 off the Zona Plus See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 12, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... … you’ll find out how your imagined future directs your behavior right now, rather than your past. You’ll learn how to manage threats to your future self, recognize truths about your future self, and how to take steps to be your future self. You’ll also gain strategies you can start using today for creating and becoming exactly who you want to be in the present moment. Benjamin Hardy, Ph.D., is an organizational psychologist and author of multiple books on how to improve your mindset. He joins the show to explain how you can borrow from your future and actually be that person right now. In his newest book, “ Be Your Future Self Now: The Science of Intentional Transformation ,” he says, “Research now shows that a person’s past does not drive or dictate their actions and behaviors. Rather, we are pulled forward by our future.” There’s no looking back, only moving ahead. Most people, out of fear, limit their view of the future to a narrow range. Take a dangerous leap to think more broadly. Take cues from your brain. “With neuroscience, the brain is essentially considered a prediction machine,” Ben says. “So, what the brain is always doing is predicting what's going to happen, and learning is essentially just updating its sense of predictions. The brain is always anticipating the future.” Since you’re already thinking about the future, put those thoughts to use in the here and now with 21 actions (7 threats to, 7 truths about, and 7 steps for being your future self) designed to transform yourself. For example: Offset a THREAT: Urgent battles and small goals keep you stuck. To exit the rat race of day-to-day mindset requires a shift in your focus. Face a TRUTH: Failing as your future self is better than succeeding as your current self. The more willing you are to invest in momentary loss and pain directed at a goal, the faster you’ll adapt to the level of your future self. Take a STEP: Schedule your future self. Put the important before the urgent. Once you commit to your Future Self, you’ll be required to be courageous. Choosing freedom over security is an act of courage. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Calm Your Nervous System: Give the sensation of a hug, deep relaxation and better sleep: https://balooliving.com/dave , use code DAVE for a special discount Tasty Keto Bread & Chips: https://www.uprisingfood.com/DAVE , use code DAVE to get $10 off the starter bundle See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 9, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... …a legacy upgrade conversation with Byron Katie will have you digging deep into the work of fine-tuning your mindset. Her keystone practice, The Work, allows you to access the wisdom you already hold inside you. She explains it as a process to “clear the mind.” You’ll ask yourself four questions and apply them to a specific problem you’re facing. Going through these steps gives you perspective and a new way of thinking about what’s causing you distress. Questioning diminishes the power your thoughts have over you. And THAT leads to true freedom. Her work contains elements of therapist, a counselor or a religious leader, though she’s technically not any one of these. She’s been described as a spiritual mentor. As the bestselling author of “ Loving What Is: Four Questions That Can Change Your Life ," followed by " A Mind at Home with Itself: How Asking Four Questions Can Free Your Mind, Open Your Heart, and Turn Your World Around ," her inspirational guidance offers people a different way to think their thoughts so they can change their mindsets and, ultimately, their lives. Her own story of early life success that spiraled into depression, rage, addiction, and self-loathing, sets the foundation for The Work. “The thoughts like, “I’m not good enough. There's something wrong with me," which was true,” Byron explains. “It was my thinking. My thoughts were aimed out at other people. It was their fault. Then when I would say or do something, I would experience the guilt, so I had this vicious circle going of judgment, guilt, judgment, guilt. It was debilitating.” She had to save herself. Several weeks into treatment, she woke up one morning to a state of constant joy that has never left her and four questions clearly in her mind that would lead her out of her own darkness. She’s never been able to truly explain this epiphany, nor has she evangelized it. She realized that when she believed her stressful thoughts, she suffered, but that when she questioned them, she didn't suffer, and that this is true for every human being. She simply shares The Work with people who want to make profound life changes—and has continued this path for nearly 40 years. “I have a lot of people across the globe that are saying their lives are shifting so dramatically they're unrecognizable, but I don't call it The Work for nothing,” she says. “It does take stillness. It takes silence, and it takes being courageous enough to look at the thoughts in your head without trying to change them and accept them the way they are.” WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Kickstart Autophagy: https://timelinenutrition.com/DAVE , use the code ASPREY10 to get 10% off any plan Mattress Temperature Tech: https://www.eightsleep.com/dave , use code dave to save $250 on the Pod Pro See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 6, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE™... ... you’re going to find out how to cook differently using an innovative kitchen appliance, Brava , that’s got some cool features that will get you excited about making your meals at home—always a good idea! First—what Brava is not . The Brava countertop cooking oven isn’t a microwave, isn’t a toaster oven, and isn’t a convection oven. Instead, it’s a device that cooks with light. Six lamps deliver exact, variable, infrared light waves to your food. Brava synchronizes and controls the amount of power each lamp emits. Simultaneously, the lamps instantly reach full power and turn off just as quickly, creating three independent cooking zones inside the chamber. The top five benefits of this cooking method include: Searing (great for your grass-fed steaks), precision, versatility, speed and quality. Brava also cooks up to three different ingredients at the same time. You can air fry, dehydrate and cook your favorite white rice in it (Bulletproof Diet approved). It’s user- and kid-friendly, so your whole family can be part of a lifestyle that prioritizes food that nourishes your body and ups your energy. Brava’s vice president and professional chef, Travis Rea, led the Brava Culinary Team in developing Brava's patented Pure Light Technology (physicists and mathematicians were in on it, too). He’s on the show to explain the technology behind Brava and how cooking with light will change your entire approach to food. Travis earned a degree in Culinary Arts at the California Culinary Academy. Prior to Brava, he headed the Food Development team at Williams-Sonoma for eight years where he developed nearly 800 private label food products. His experience also includes leadership roles at Revolution Foods and NatureBox. So, he knows the many facets of creating great food. Brava takes out the guesswork of meal planning by offering over 7,000 fully automated recipe programs. This means you can enjoy cooking more because it takes less of your time. SPECIAL OFFER FOR LISTENERS OF THE HUMAN UPGRADE: https://www.brava.com , use code DAVE at checkout to get $200 OFF any Brava set through December 31, 2022. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 5, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... … you’ll learn how whole body vibration works and the many ways it benefits your physiology. It’s the nexus between energy and life, says Tony Molina, a performance optimization expert. “ This biohack helps you burn more calories,” he says. “It helps you increase strength and reaction time. You can improve skin and circulation, bone density, pain relief, hormonal changes, posture and balance. It's also a lifelong health and longevity partner.” He’s talking about the Power Plate . He’s a high-altitude and longevity researcher and Senior Research and Development Specialist at the company. “Whole body vibration runs off Isaac Newton's second law, so force equals mass times acceleration,” he explains. “Where acceleration is what’s being increased versus mass. And generally, we focus on the mass, whether we do any kind of strength training, we focus on holding mass or dealing with the mass or changing the mass. With whole body vibration and Power Plate, you’re focusing on the acceleration or the speed change.” Other cool things about whole body vibration: You're changing the formula from conscious effort (like conventional exercise) to subconscious (harmonic vibration). You’re experiencing multiplanar movement that creates an unstable environment that’s proprioceptively challenging. (The nervous system doesn't know what to do, which is a good thing.) Your neuromuscular spindle gets stimulated without the need for the brain even to get involved. (Cognitive confidence!) Your nervous system itself is ramping up safety signals so the brain understands what it needs to do without you consciously having to do anything. Your reflexes improve; your reaction time gets better; your ability to propriocept allows your posture to improve; and you breathe better. Listen on to find out more about whole-body vibration training, therapy, and how it can make you live longer, whatever your fitness level or ability. SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: https://powerplate.com/dave to get 20% off a Power Plate® MOVE (save $659) AND a FREE Power Plate Pulse Massage Gun (valued at $249.99 ) WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Increase BDNF and Support Neurogenesis: Go to https://nootopia.com/davegenius , use code DAVE10 to get an extra 10% off A Cleaner Nicotine Alternative: https://lucy.co , use code DAVE20 for 20% off your first order of pouches, gums or lozenges Cooler Temps for Deeper Sleep: https://www.chilisleep.com/ , use code HUMANUPGRADE20 to save 20% on the Dock Pro Sleep System See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Aug 2, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... …you’ll learn about the critical role metabolism plays in your body’s energy and performance. Important new science findings about human metabolic health shows how you can change your metabolism. To help you make these changes, this episode gives you practical tips and tools for measuring your metabolism and ways to manage it effectively. Guest Michal Mor, Ph.D., co-founded Lumen with her twin sister, Merav Mor, Ph.D., and three long-time entrepreneur friends nearly a decade ago. As Chief of Metabolic Health & Science, Michal’s background includes degree studies in Medical Laboratory Sciences and Physiology with an emphasis on cardiac arrhythmia. The Lumen founders set out to close the gap of what existed in the science and something people could actually use to manage their metabolic health. Both Michal and her twin, Merav, were multiple-year Ironman participants. Athletic performance—and how to improve it—influenced their work with metabolism. Four years of research and development plus more years of validation studies and beta test users went into developing Lumen. Lumen is a hand-held device that accurately measures your metabolism through the breath. It uses a CO2 sensor and flow meter to measure the CO2 concentration in your breath, indicating if your body is in carb or fat burn. “So, this ability to shift between them, it's not only good for athletic performance it's also improving our quality of life,” Michal says. “It enables us to enjoy life to our fullest potential. It's about longevity. It's about being able to achieve our goals, not having those mood swings. This is so much more than improving athletic performance.” Lumen has accumulated a metabolic measurement database with over 20m measurements. These insights have shown how lifestyle habits affect metabolism and the body more than previously thought possible. Listen on to learn how with just one breath in the morning, you can set your metabolism course for the day and then monitor it throughout the day. SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: https://lumen.me , use code Asprey50 to get $50 off a Lumen device WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Experience the High Life with Infrared Therapy: https://higherdose.com and use code HUMAN10 for 10% off your entire purchase. Capture Life Force Energy : https://leelaq.com , use discount code DAVE10 to get 10% off sitewide Business Growth With SEO: https://www.stephanspencer.com , get a FREE consultation See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 30, 2022

In this Episode of The Human Upgrade™...​ Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month. Tattoos can help monitor your blood pressure Device that protects against head injuries Upgrading your avocado toast Ways to manage the harmful aging-inflammation duo Pee recycling does the soil good EPISODE SPONSOR: The Eng3 NanoVi device helps repair oxidative stress damage and support the body’s natural repair mechanisms. https://eng3corp.com/DAVE/ . Learn more: The Anti-Aging Science Behind the NanoVi Device – Rowena Gates & Hans Eng – #416. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 29, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... … you’ll find out why aging and stress are the major contributors to neurodegenerative diseases in your lifetime, what you can do to stave off the effects, and how you can kickstart your brain into functioning at a way higher level. You’ll also learn about: BDNF (Brain-Derived Neurotrophic Factor) and ways to increase it Options for how you can support your brain’s neurogenesis How certain mushrooms and collagen can be used to increase your cognitive function —so you can focus, concentrate and be more creative How customized nootropics can help you reach peak mental performance Matt Gallant keeps coming back on the show to introduce innovative supplements that work with your brain and body. We’ve talked about nootropics, psychobiotics, magnesium, enzymes, blood sugar, gut health and more. As co-founder of BiOptimizers , Matt makes important connections within body systems and finds unique ways to maximum human performance. After a personal health scare with his own brain, he’s turned his professional attention to hacking and upgrading the brain in as many ways as possible. Most people’s brains aren't at 100% due to many factors, he says, like lack of sleep, chronic high stress, an inadequate diet, and overuse of certain drugs and prescriptions. Mr. Noots, (scientist Mark Effinger) teamed up with Matt on this quest to support brain health and improve cognitive function. After a childhood exploring everything science, chemistry and physics, he joined the US Air Force and became an endurance athlete and bodybuilder. His life, like Matt’s, took an unexpected turn and he struggled with health issues. It took creative, performance-enhancing nutrition to get himself well. He’s now Chief Product Officer for the mind-enhancing compounds and stacks of nootropics at Nootopia and works side-by-side with Matt. Their newest product, CollaGenius, combines powerful mushroom extracts and collagen into a formula specifically to energize your brain and body. Collagen improves skin health, relieves joint issues, strengthens hair and nails, and prevents bone loss—and it also does your brain a lot of good. And here’s what the mushrooms do for you in the right amounts. That’s the key principle—the dose creates the effect. Lion’s Mane : Boosts BDNF Chaga : A natural anti-inflammatory that supports immunity Reishi : Alleviates stress Cordyceps : Elevates athletic performance and maximizes brain health Together, Matt and Mr. Noots continue pushing limits and finding ways to make your brain operate at its highest capacity. SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS Go to https://nootopia.com/davegenius , use code DAVE10 to get an extra 10% off. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Mineral-Rich Salt with Micronutrients: https://oryxdesertsalt.com , learn more at the website and purchase through Whole Foods A Cleaner Nicotine Alternative: https://lucy.co , use promo code DAVE20 for 20% off your first order of pouches, gums or lozenges. Isometrics for Cardiovascular Health : https://www.zona.com , use code DAVE2022 to get $150 off the Zona Plus See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 26, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... …two psychiatric research pioneers open up about the benefits people experience from psychedelic treatments. From mental health conditions to crucial social connections, there’s a dose and approach that can work for you and with your own brain chemistry. Psychiatrist and psychotherapist Dr. Phil Wolfson , creator of Ketamine Assisted Psychotherapy, leads patients through psychedelic psychotherapy sessions, guiding them through their past and present in an open, altered state of mind. His invaluable work is the result of an intense, many-decades-long clinical practice. He focuses on new pathways for healing depression, PTSD, addiction and other conditions. “There’s really no right or wrong with psychedelics,” Dr. Wolfson says. “It’s about how do we integrate our lives and relationship in this very difficult time with people and in our beings, and what practices we bring to this whole thing. So, it’s not just about substances.” Psychiatrist and psychopharmacologist Dr. Julie Holland explains in her book, “ Good Chemistry: The Science of Connection, From Soul to Psychedelics ,” why you need connection, how you’ve lost it, and how you might find it again. She believes psychedelics can help. Taken under the direction of a trained psychiatrist, they can catalyze a connection with the self, nature, or the cosmos. Dr. Holland’s research—with a focus on the parasympathetic nervous system—dives into how you can “turn on” and “tune in” to the brain chemistry that supports connection. At the same time, you can tamp down the fight or flight mode that derails sleep, metabolism, libido and much more. She’s leading new understanding about how your behaviors are driven by the hormones and neurotransmitters that make up good (and bad) brain chemistry, including testosterone, estrogen, dopamine, serotonin and most crucially, oxytocin. If you liked this special episode with Phil and Julie, you’ll learn even more from listening to their full podcasts on these topics: Your Guide to Psychedelic Psychotherapy – Dr. Phil Wolfson with Dave Asprey – #770 Psychedelics Offer New Solutions for Social Isolation – Dr. Julie Holland with Dave Asprey – #757 WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Structure Water Molecules; Achieve Body/Brain Coherence: https://analemma-water.com , use code DAVE10 for 10% off Complete Brain Nutrition with Nootropics: https://neurohacker.com/dave , use code DAVE to score an extra 15% off Qualia Mind Hydrate with Electrolytes: https://DrinkLMNT.com/DAVE , get a FREE LMNT Sample Pack with 8 single-serving packets for the cost of shipping ($5 for U.S. customers) See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 21, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... …Dave’s travels take him to Amsterdam where he talks with psychic psychologist Joy Martina about intuition, hypnosis and joyful learning. Here’s some of the “how-to’s” you’ll learn about in this episode: How to find the right hypnotist for you How to identify three common misperceptions about hypnosis How to tap into your own intuition and tune into your own wisdom How to recognize your body’s kinesthetic channel How to learn through joyful and pleasurable experiences How to listen to your gut just as much as your brain How to use your energy for good How to draw from the quantum field How to connect to your highest potential Ho to create big change in your life How to tune into your environment How to recognize the benefit from staying stuck in old patterns and make a shift How to notice your triggers and react less to them How to move from an emotionally charged attached position to a grounded, neutral state. After this episode, head into the podcast library for Joy’s previous conversation with Dave: Intuition is Not a Feeling – #574 . About Joy Martina: Joy Martina, psychic psychologist and a channeler of Christallin Consciousness specializes in high-level intuitive intelligence training for entrepreneurs, business owners and celebrities. She is an author, the creator of the Christallin Oracle Training, a master hypnotist and trainer of trainers. Must-Have Magnesium: https://magbreakthrough.com/dave , use code DAVE10 to get a 10% discount Mattress Temperature Tech: https://www.eightsleep.com/dave , use code dave to save $250 on the Pod Pro Business Growth With SEO: https://www.stephanspencer.com , get a FREE consultation See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 20, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... … Swedish journalist Johan Anderberg joins the show to talk about how he captured a rare moment in his country’s history during the worldwide COVID-19 pandemic in 2020. His book, “ The Herd: How Sweden Chose Its Own Path Through the Worst Pandemic in 100 Years ,” explains this unique time. In it, he gives a fly-on-the-wall account of the herd-immunity strategy that Sweden adopted during the first year of the pandemic. First, the government instituted no restrictions . Then, it declined to order that people wear face masks . While the rest of the world looked on with incredulity, condemnation, admiration, and even envy, Sweden stood alone in its decisions. “We have to value the fact that different countries do different things,” Johan says. Here’s what you’ll learn by listening: How the Swedish COVID-19 strategy veered far from what the rest of the world was doing. Why "The Swedish Experiment” has been alternately praised and held up as a cautionary tale. In what ways Sweden’s laissez-faire strategy with few restrictions worked. Differing perspectives— no judgment or right/wrong —about the actions and reactions of governments, communities and individual citizens during a medical crisis. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Save Time, Burn Fat, Build Muscle: Visit https://powerplate.com/Dave to save 20% off for a limited time and Probiotic Eases Stress: https://www.omnibioticlife.com/DAVE , use code DAVE20 to get 20% off receive a FREE Power Plate massage gun with purchase Sleep Better on Natural Memory Foam: https://myessentia.com , use code DAVEVIP to get an exclusive discount See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 14, 2022

In this Episode of The Human Upgrade™...​ … Dave talks with George Hanna about how to get better deep sleep. George says he’s been a health and fitness buff for most of his life. Now in his early 60’s, he’s adopted much of the biohacking lifestyle, including sleep hacks. Yet, deep sleep continues to elude him. He and Dave get into factors that could be messing with his circadian rhythm, like temperature, light, overtraining, heart rate variability, glucose monitoring, blood sugar and more. They also go over potential tweaks to: Mushrooms Herbs Amino Acids Testosterone Supplements Thyroid Statins If you struggle with sleep or simply want to learn to fine-tune the sleep you’re getting, take a listen to this episode for tips and resources. Listen to the other episodes in the Interventions With Dave series and don’t miss the “Links & Resources” section on the episode web page: https://daveasprey.com/intervention-george-hanna-957/ Note: The "Interventions With Dave” recommendations are designed to help you upgrade yourself and your biology so you can perform better at everything you do. They are not, however, a substitute for advice or treatment by a trained medical professional that may be needed for specific health conditions, illness or injury. WE APPRECIATE OUR PARTNERS, CHECK THEM OUT! Over-the-head Pillow for Better Sleep: https://www.sleepcrown.com/dave to save $15 and get free U.S. shipping NAD+ for Brain Health: https://innovativemedicine.com/DAVE and save 20% Science-backed, Music-driven Breathwork : Go to https://www.othership.us/dave , sign up for the app and get two weeks free. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 13, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... …anesthetist and researcher, Mark Harper, M.D., Ph.D., shares how the power of cold-water practices can treat depression, anxiety, PTSD, arthritis, migraines and other health conditions you may be experiencing. Despite all the attention cold water swimming and immersion has gotten in recent years—thank you, Wim Hof—the scientific community hasn’t taken it very seriously. That’s changing now. Dr. Harper’s research goes beyond what we already know about the benefits of cold-water therapy and lays out best practices for you. In this episode you’ll learn: How to safely establish your own customized practice of cold-water swimming The ideal plunge frequency How to heat your body from the inside out Why using saunas can optimize your plunges The effects of putting your face in cold water vs. just your body Why swimming “in the wild”—lakes, rivers, seas — benefits you even more How community plays a role in cold plunge practices And more You’ll also learn about science and case studies found in Dr. Harper’s new book, “ Chill: The Cold Water Swim Cure - A Transformative Guide to Renew Your Body and Mind .” He explains how cold water has the ability to impacts us physiologically and mentally. As Dr. Harper shares his long-awaited evidence on cold-water’s therapeutic power to strengthen the immune system, cell regeneration, and everyday vitality, you’ll come to understand how to harness the power of cold-water swimming. If you are looking to up your cold-water therapy game, you’ll get a lot of value from this episode. Dr. Harper says you can start simply, one small movement into cold water at a time: “Your rest, digest, chill out, and anti-inflammatory response comes from putting your face into the water,” he says. He then goes on to other cold-water swim tips. Enjoy! WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Experience the High Life with Infrared Therapy: https://higherdose.com and use code HUMAN10 for 10% off your entire purchase. Tasty Keto Bread & Chips: https://www.uprisingfood.com/DAVE , use code DAVE to get $10 off the starter bundle Complete Spectrum Hemp + Chinese Herbs: https://radicalrootsherbs.com/DAVE , use code DAVE to get 10% off. Learn more about Radical Roots on these podcasts! Your Get-Smart Guide to CBD & Chinese Herbs #938 Body Out of Balance? Bring it Back to Harmony with Chinese Herbal Medicine #737 See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 8, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... …two of the most adventurous people on the planet share what they’ve uncovered, faced and learned through exploration of the planet’s deepest waters. From discovering the Titanic to cave diving in places untouched by any other human, Bob Ballard and Jill Heinerth took risks, dove into fear, and came up for air with tremendous new knowledge. Combined, they’ve spent over nine decades searching the seas and documenting their findings. Canadian Jill Heinerth explores the underwater world as one of the greatest cave divers on the planet. She’s considered this generation’s Jacques Cousteau. She’s completed more than 7,500 dives in her career so far and dived deeper into caves than any woman in history. She became the first person to dive the ice caves of Antarctica, going further into an underwater cave system than any woman ever. She’s gone into places in the world where no one had gone before. Considered a legend in the diving community, she’s spent more than 30 years in submerged caves around the world partnering with National Geographic, NOAA, and various educational institutions and television networks worldwide. She’s also a writer and award-winning photographer and filmmaker who takes a keen interest in the health of the Earth’s oceans. Learn more about Jill’s lifetime of underwater cave diving in her memoir, “ Into the Planet: My Life as a Cave Diver .” “We are capable of so much more than we could possibly imagine," she says. Bob Ballard explores the vast depths of the oceans uncovering mysteries, proving theories, and revealing artifacts that tell a story about the history of humankind. An oceanographer and marine geologist, he’s led nearly 160 deep-sea expeditions and worked with the Navy on top-secret missions. His underwater career spanning more than 60 years began simply enough as a child with a love of California’s Mission Bay tide pools. He’s gone on to discover ships thought long lost (the RMS Titanic in 1985) and provide extraordinary new understandings and discoveries in marine geology, geophysics, biology, and chemistry. He’s discovered new life-forms, traced ancient trade routes, developed robots that roam the ocean floor, and opened the underwater world to kids through telepresence. Bob's recent memoir chronicles his underwater journeys “ Into The Deep: A Memoir from the Man Who Found Titanic .” “Just lots of crazy things have happened, and I'm still at it and I'm not going to quit,” he says. If you liked this special episode with Jill and Bob, you’ll learn even more from listening to their full podcasts, directly below. Living a Life of Deep Adventure – Bob Ballard, Finder of the Titanic – #839 A Lesson in Adventure Hacking: Step Toward Your Fear – Jill Heinerth – #663 WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Repair Oxidative Stress Damage: https://eng3corp.com/DAVE/ Kickstart Autophagy: https://timelinenutrition.com/DAVE , use code ASPREY10 to get 10% off any plan Control Blood Glucose: https://pendulumlife.com , sign up for membership to get monthly supply delivery, use code DAVE20 to save $20 on your first shipment See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jul 6, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... …a legacy upgrade conversation with Paul Chek delivers the goods on how to improve your physical, emotional and mental performance. He lays out what it takes to get into your optimal state—including a higher state of consciousness. For more than 30 years, he’s used a unique, integrated approach to treatment and education. Paul gets back to basics and formulates practical systems that work to help you help yourself to get well. “I look at happiness, movement, quiet, and diet,” Paul says. “I get a holistic picture of their life because you can’t reduce a living philosophy below those four factors.” Paul's an expert in the fields of corrective and high-performance exercise kinesiology, stress management and holistic wellness. By treating the body as a whole system and finding the root cause of a problem, he’s been successful where traditional approaches have consistently failed. And he goes even further into the metaphysical realm. “The world populace due to the destruction of the environment, due to the chemicals in the environment, due to the electromagnetic pollution, due to overstimulation, due to the lack of sleep, due to the manipulation of people’s biochemistry by medical drug use, … we’re going lower and lower into our levels of consciousness, which is putting us more and more in a fight or flight state, which is making us more and more reactive.” But you can make a difference within your own life, even going into higher levels of consciousness, Paul explains. “Every human being has genius within it,” Paul says. “We can use the same technology and the same level of brain power that got us in trouble to reverse it.” This legacy episode is the full version of a 2-part episode series. Now, you can listen to the entire conversation without interruption. Paul tells it like it is—no holds barred and no BS. You’re going to learn a lot and enjoy his style! About Paul Chek: Paul founded the CHEK Institute (Corrective Holistic Exercise Kinesiology) in 1995. He’s a certified neuromuscular therapist and clinical exercise specialist (ACE) who’s studied with experts worldwide from many disciplines. The Chek Institute offers a broad range of educational courses that include at-home study. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Mattress Temperature Tech: https://www.eightsleep.com/dave , use code dave to save $250 on the Pod Pro Must-Have Magnesium: https://magbreakthrough.com/DAVE , use code DAVE10 to get a 10% discount Business Growth With SEO: https://www.stephanspencer.com , get a FREE consultation See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 30, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... …two spiritual masters continue discovering new layers of and models for human experience. This combined episode covers aspects of consciousness, conscious agents, biodynamics, emotional body energy, the Enneagram, homeopathy and much more. Deepak Chopra , M.D., FACP, is a world-renowned pioneer in integrative medicine and personal transformation. TIME magazine described him as “one of the top 100 heroes and icons of the century.” He’s been exploring the intersection of science and spirituality for decades. Deepak’s 90th book: “ Metahuman: Unleashing Your Infinite Potential ,” gets into what it means to be “beyond human.” You’ll learn how to question reality, move past limitations constructed by your mind, and enter a new state of awareness. And when you realize a “reality without limits,” you’ll be able to realize your full human potential. Abdul Hayy Lammert Holdijk has followed a Sufi path for the past 40 years, studying religion and consciousness with a hefty dose of pragmatism. He lectures on topics such as Epigenetics, Neurobiology, the Enneagram, Shadow Work, Voice Dialogue, Love, Dream interpretation, Jekyll and Hyde, Hayy Ibn Yaqzan, and a wide range of other topics related to consciousness and personality development. Abdul taught at the American University in Beirut for several years, and then at the American University in Cairo for 35. His profound life story includes adventure, spirituality seeking, questioning tradition and teaching others. He also leads spiritual retreats in Lebanon, Egypt, Oman, and the surrounding region. If you liked this special episode with Deepak and Abdul, you’ll learn even more from listening to their full podcasts, directly below. Going Beyond the Human Mind to Discover Your Infinite Potential – Deepak Chopra – #683 Who Am I? Finding Spirituality by Disrupting Tradition with Abdul Hayy L. Holdijk – #710 WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Complete Brain Nutrition with Nootropics: https://neurohacker.com/dave , use code DAVE to score an extra 15% off Qualia Mind Hydrate with Electrolytes: https://DrinkLMNT.com/DAVE , get a FREE LMNT Sample Pack with 8 single-serving packets for the cost of shipping ($5 for U.S. customers) Business Growth With SEO: https://www.stephanspencer.com , get a FREE consultation See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 28, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... ...you'll learn some surprising lessons sorrow and longing can teach you about creativity, connection and love. You’ll find out why longing isn’t passive—as most people think—but actually “momentum in disguise.” Author Susan Cain combines research, the stories of others, and memoir to explain how sadness can be your superpower. “Bittersweetness is the hidden source of our moon shots, masterpieces, and love stories,” she says in her newest book, “Bittersweet: "How Sorrow And Longing Make Us Whole” . Longing can improve your creativity and fuel a drive to express yourself. Longing coupled with pain can help you to connect to others and provide a common ground that enhances compassion and helps you feel less alone in your troubles. Instead of hiding or shying away from feelings like sadness and longing, Susan encourages you to embrace them as part of who you are, and part of what it means to be human. This conversation gets into: How bittersweet differs from melancholy How Acceptance Commitment Therapy helps you manage the “bitter of life” How sadness is the ultimate bonding agent How the concept of “winners” and “losers” changed over time How to live and work authentically in an environment of enforced positivity How to embrace deep reflection and ask yourself: "What. Are. You. Longing. For?" Special offer for The Human Upgrade listeners : Go deeper into the topics of Bittersweet and Quiet with Susan’s 30-day interactive online courses. Go to https://www.susancain.net / and use code ASPREY15 to save 15%. More about Susan Cain: She’s the author of “ QUIET: The Power of Introverts in a World That Can’t Stop Talking ,” which spent seven years on The New York Times bestseller list and has been translated into 40 languages. Her record-smashing TED Talk, “ The Power of Introverts ,” has been viewed over 30 million times. She’s spoken at Microsoft, Google, the U.S. Treasury, the S.E.C., Harvard, Yale, West Point and the US Naval Academy. She’s an honors graduate of Princeton and Harvard Law School. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! A New Peptide Builds Healthier Skin: https://www.oneskin.co , use code DAVE15 to get 15% off Trigger Autophagy : https://spermidinelife.us/dave , use code DAVE25 for 25% off your first month’s order 8th Annual Biohacking Conference: https://biohackingconference.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 24, 2022

In this Episode of The Human Upgrade™...​ Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month. How a gene interferes with memory linking in the brain. How fearful memories are seared into your brain. How a new device stimulates the vagus nerve to help people learn a new language. How global warming impacts your sleep quality. How and why people age, according to a new theory. EPISODE SPONSOR: Infrared Sauna Benefits: https://www.sunlighten.com/dave . Save up to $600 on your sauna purchase! Mention code "DaveAsprey" for discount. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 24, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... …two food experts explain the many ways your food choices influence your body systems—and what you can do differently to improve your gut function, energy and performance. Here’s a look at how essential amino acids and the right proteins can keep inflammation at bay and keep your metabolism humming. Teri Cochrane, CN, CCP , went down the research rabbit hole when both her son and daughter (at different ages and for different reasons) experienced severe health problems. She not only examined nutrition in-depth, but she also investigated epigenetics and nutrigenomics “Disruptors such as pathogens, mycotoxins, stress, amyloids and inflammatory foods work together to impair body balance,” Teri says. “We have found a direct link between amyloids, mycotoxins and these health disruptors in the acceleration of disease.” She’s developed her own methodology that integrates a multi-level nutritional approach—including biochemistry, nutrition, genetic tendencies, herbology, supplementation and counseling. As the author of the “ The Wildatarian Diet: Living as Nature Intended ,” Teri lays out how the malabsorption of protein, fat, and sulfur, tamper with gene expression. Mareya Ibrahim believes in food flexibility while still focusing on a core system that works. She’s a holistic nutritionist, TV chef, podcast host, and award-winning entrepreneur and inventor with more than 25 years of experience in the food industry. She also founded Grow Green Industries and co-invented the patented eatCleaner line of products. In her book, “ Eat Like You Give a Fork: The Real Dish on Eating to Thrive ,” she explains the nuances of clean eating, how to reset your taste buds, and all the ways essential amino acids keep your body functioning. “Essential amino acids are what fuel us and allow us to regulate our hormones, and flex our metabolisms, and build muscle, and all of the things that we need to be functioning human beings,” Mareya says. If you liked this special episode with Teri and Mareya, you’ll learn even more from listening to their full podcasts,: What You Eat is Turning Your Genes On and Off – Teri Cochrane – #646 Just Give a Fork: Eat the Freakin’ Pasta – Mareya Ibrahim – #661 WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Meat Sticks! All the Good Stuff-No BS: https://paleovalley.com/DAVE , use code DAVE to get 15% off your first order Fitness Center of the Future: Check out franchise opportunities for biohackers at https://ownanupgradelabs.com NAD+ for Brain Health: https://innovativemedicine.com/DAVE and save 20% See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 21, 2022

TWO SPECIAL OFFERS FOR LISTENERS OF THE HUMAN UPGRADE! Visit https://paleovalley.com/humanupgrade to get your first 10-pack of meat sticks for only $4.99 + shipping. Visit https://wildpastures.com/dave to get a special discount for a limited time on regenerative meat delivery. IN THIS EPISODE OF THE HUMAN UPGRADE™... …you’ll learn how eating meat benefits human health, including protein specifics and the clear advantages of regenerative agriculture. Today’s guest suffered from debilitating digestive issues and crippling anxiety for most of her life. Specialist after specialist told Autumn Smith nothing could be done to alleviate her physical and mental health distress. As a last-ditch effort, she turned to the power of whole foods. She cleaned up her diet with Paleo-inspired eating and improved her gut in just 30 days. The changes also decreased her anxiety, increased her mental sharpness, and discovered her inner vibrancy. That experience propelled Autumn to help others capture the power of whole foods through quality food products produced by regenerative agricultural practices. In 2013, she and her husband, Chas, along with another family member and friend, launched Paleovalley . They built a company dedicated to helping people get essential nutrients without added sugars, grains, and other harmful ingredients. With meat being the central focus of their business, they set out to learn all they could about production and regenerative farming. In 2018, they launched Wild Pastures , a regenerative meat delivery service, and recently opened Wild Pastures Burger Company , their flagship fast casual burger restaurant in Boulder, Colorado. This conservation gets into the problems with current methods of animal agriculture and possible solutions. You’ll find out more about the nutritional differences of animal products depending on how they’re raised. Autumn says meat labels can be tricky, too, so she breaks down the jargon and tells you what to look for and what to avoid. Autumn advocates for meat’s many advantages and works to dispel the myths that continue to persist about meat consumption. From soil to farming to raising animals humanely, building community and managing economies, Autumn talks about how to make choices that are right for you and everything around you. More about Autumn Smith: Autumn holds a master’s in Holistic Nutrition and currently is a doctoral candidate in Holistic Nutrition. She’s a Functional Diagnostic Nutrition Practitioner, an Eating Psychology Coach certified by the Institute for the Psychology of Eating , and received Soil Advocacy Training by Kiss The Ground. She hosts the popular Optimize Paleo podcast. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Control Blood Glucose: https://pendulumlife.com , sign up for membership to get monthly supply delivery, use code DAVE20 to save $20 on your first shipment Fitness Center of the Future: Check out franchise opportunities for biohackers at https://ownanupgradelabs.com Must-Have Magnesium: https://magbreakthrough.com/DAVE , use code DAVE10 to get a 10% discount See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 18, 2022

In this Episode of The Human Upgrade™...​ … Dave talks with Lisa B. about the frustration she’s experiencing with her health conditions. She says she lives a healthy lifestyle and does the “right things” and still struggles with chronic low energy. Her kids often say, “you never feel well, mom.” She agrees but finds it difficult to explain why. Now in her early 50s, she’s had panic attacks and anxiety since childhood and has taken many types of anti-depressants throughout her life. She also struggles with OCD. She’s experienced long-time hormonal imbalances, including painful periods, acne, fertility problems, and ongoing PMS “flu” that she says takes over her life during her cycles. She suffers from aggressive seasonal allergies and has a shellfish allergy. She’s been on Accutane, was diagnosed with Lupus in college and also diagnosed with exercise-induced urticaria and Mast Cell Activation Syndrome. She got COVID in 2021. In this “Interventions With Dave” episode, Dave examines what’s going on with Lisa’s varied symptom. They discuss what’s working and what’s not, and what can help her gain more energy and control of her health. The conversation gets into a bunch of topics, like: PMS “flu” (with sore throat, hot tongue, achy, brain fog, no energy, feverish feeling with no fever present, painful periods) Hormones, the Wiley Protocol and testosterone “Mold cough” and other symptoms of mold OCD and anxiety MTHFR gene mutation Histamine, Mast Cells and Mast Cell Activation Syndrome Allergies And much more… Find biohacking tips, tools and resources particular to this episode on the episode web page: https://daveasprey.com/interventions-with-dave-lisa-b-949/ Note: The "Interventions With Dave” recommendations are designed to help you upgrade yourself and your biology so you can perform better at everything you do. They are not, however, a substitute for advice or treatment by a trained medical professional that may be needed for specific health conditions, illness or injury. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 17, 2022

SPECIAL OFFER FOR LISTENERS OF THE HUMAN UPGRADE: Go to beamminerals.com/advancedset . Use code DAVE to get 20% off. IN THIS EPISODE OF THE HUMAN UPGRADE™... …you’ll find out how plant-based humic substances have the power to stop and reverse the effects of glyphosate damage in both humans and soil. Caroline Alan, co-founder and CEO of BEAM Minerals , explains how minerals provide your body systems with critical cellular support, how they get depleted and how you can replenish them. She goes even further to talk about glyphosate’s harmful effects on human health and soil health, particularly when it comes to minerals. In her former corporate career of software development and business consulting, Caroline experienced problems physically, mentally and energetically. She struggled with issues like life-long gluten intolerance, whole-body inflammation, leaky gut, chronic headaches, flat-lined adrenals and low thyroid. Her chronic health issues didn’t resolve until she began taking plant-based humic and fulvic minerals. This cellular support changed her life so dramatically, she started deep research into the science of minerals and co-founded BEAM Minerals. Then she kept going and began to look more closely at the current problems with farming in soils that have become unproductive due to a lack of microbial and mineral content. She investigated the effects of glyphosates on soils and in the human body and found: One of the root causes of unhealthy soil can be linked directly to glyphosate use in modern production farming. One of the root causes of mineral depletion and chronic illness in modern humans points directly to glyphosate ingestion. The bottom Line? We all have glyphosates in our bodies. Here's what it can do: Suppress critical enzymes, create gut dysbiosis, chelate minerals from your system, reduce mitochondrial function, and cross and affect the blood–brain barrier. Studies also show more use of glyphosate can lead to an uptick in chronic and acute health conditions. Research finds that plant-based humic and fulvic substances offset glyphosate harm. This conversation will help you recognize symptoms of mineral depletion in your own body. You’ll get practical tips about how to use 100% bioavailable, plant-based fulvic and humic mineral supplementation in easy forms like liquids and topical spray. BONUS: For research links and other resources about glyphosate and humic/fulvic substances, visit daveasprey.com/glyphosate . WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Complete Spectrum Hemp + Chinese Herbs: https://radicalrootsherbs.com/DAVE , use code DAVE to get 10% off Tasty Keto Bread & Chips: https://www.uprisingfood.com/DAVE , use code DAVE to get $10 off the starter bundle 8th Annual Biohacking Conference: https://biohackingconference.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 15, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE™... … you’ll get tips about how to lead a brain healthy lifestyle and how to keep perspective along your own entrepreneurial journey. Activism, acting and entrepreneurship are wired into Patrick Schwarzenegger’s DNA. He thoughtfully balances each passion through his work as an Alzheimer’s advocate, actor, investor and food founder. Patrick’s known for his trend-spotting abilities in the better-for-you food and beverage industry. He got into the fast-casual Blaze Pizza franchise when he was just a teen. That experience solidified his interest in health and wellness: “invest solely into entrepreneurs and companies that were providing Americans with the healthier alternative." He’s now an active investor and advisor to numerous brands and helps founders scale their emerging businesses to the next level. His latest venture encourages brain health at every age and supports programs, research, and lifestyle choices designed to make your brain work better. Patrick co-founded a new brain health food brand called “ MOSH ” with his mom, Maria Shriver , designed specifically to up-level your brain function. “We really want it to be a brand that was created out of a mission and out of the why, and not so much the what,” Patrick says. … “We want to be a brain health company and also educate consumers and raise money and donate that to the Women's Alzheimer's Movement. So, it's been an amazing journey.” A journey with its share of mishaps, too: “We had so many things that went wrong and that was kind of the fun part was learning about that and finding ways to fix it. That's wanting to be an entrepreneur or that's embarking on that journey, you're going to have speed bumps. You can do as much homework as you can and want and try to perfect everything before you launch, but things come out of left field every single day.” He’s on the show to discuss entrepreneurship, how to invest, how to build brands, how to hire the right people and what’s possible for high-functioning brains at every age. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! A New Peptide Builds Healthier Skin: https://www.oneskin.co , use code DAVE15 to get 15% off Minerals for Cell Function: https://www.beamminerals.com , use code DAVE20 to get 20% off Unlock Your Brain with Customized Nootropics : https://nootopia.com/dave , use code DAVE10 to save 10% on your first order See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 10, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... … you’ll learn how your cells, mitochondria, immune system, sleep patterns, inflammation, nerve growth pattern, and energy levels all benefit from mushrooms. These fungi are full of compounds and nutrients that your body will love. There’s a whole lot of science behind this now. In this special podcast edition, you’ll hear how two mushroom experts are studying and harnessing the amazing powers of mushrooms for the deepest parts of human biology and the natural environment. Paul Stamets , is a speaker, author, mycologist, medical researcher and entrepreneur. He’s considered an intellectual and industry leader in habitat, medicinal use and production of fungi, and he considers himself a “mycological warrior.” He’s spent over four decades in the Pacific Northwest studying and researching the world of mushrooms. Listening to him describe, decode and illuminate the workings of the mushroom world is an enthralling experience, indeed. He says we’re intertwined with mushrooms at a cellular level. He believes that habitats have immune systems—just like people—and mushrooms are cellular bridges between the two. Our close evolutionary relationship to fungi can be the basis for novel pairings in the microbiome that lead to greater sustainability and immune enhancement. And from neurogenesis to our microbiome to our mitochondria, fungi are linked to us. He’s also making some amazing discoveries having to do with bears, bees, butterflies and biodefense. Mycelium Just Might Save the Bees, And Us – Paul Stamets – #624 Learn more at fungi.com Julian Mitchell, —co-founder and CEO of the Australian-based company Life Cykel—and his team work with mushrooms as innovative food sources and medicinals in Australia. “Mushrooms and mushroom-based foods are going to play a huge role in the future of food,” Julian explains. “They grow quickly requiring very little resources in terms of water, power, and land. They have an amazing nutritional profile, and of course, they are 100% natural.” … “Mushrooms are almost an uncharted continent, with infinite applications not just in food but in biotechnology.” For day-to-day use, you’ll want to go with cooked, not raw, mushrooms. For those of you who aren’t fans of eating mushrooms, there’s an option for you, too: “Having it as a tincture makes it very easy to add to a coffee, add to a tea, add to a smoothie,” Julian says. “It’s quite tasteless and at the same time micro-dosing it in small amounts straight into your mouth is a great way to have it as well and absorb it straight into your blood system.” Mushrooms Are Your New Anti-Aging Strategy – Life Cykel #603 Learn more at lifecykel.com WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Science-backed, Music-driven Breathwork : Go to https://www.othership.us/dave , sign up for the app and get two weeks free. Fitness Center of the Future: Check out franchise opportunities for biohackers at https://ownanupgradelabs.com Kickstart Autophagy: https://timelinenutrition.com/DAVE , use the code ASPREY10 to get 10% off any plan See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 8, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... … you’ll learn why every breath you take makes a difference in how your entire body functions. The way you breathe affects the quality of your life and every one of your body systems. Full stop. This goes for adults and kids alike. In this special edition, breathing experts Patrick McKeown (“ THE BREATHING CURE: Develop New Habits for a Healthier, Happier, and Longer Life ”) and James Nestor (“ Breath: The New Science of a Lost Art ”) approach the topic from diverse perspectives, but agree on a lot. Especially the benefits of nose breathing and the detriment of mouth breathing. They explain the biochemical, biomechanics and psychological components of how you breathe. They also present exciting new research in pulmonology, psychology, biochemistry and human physiology that shows how making even slight adjustments to the way you inhale dramatically influences things like: sleep and snoring fitness and athletic performance brain function focus and concentration oxygen intake heart rate and blood pressure blood sugar internal organ function nervous system respiratory health asthma and allergies autoimmune disease sex female hormones pain stress and anxiety That's just the start of what you can change when you change your breathing. Big claims, yes. All true. And even bigger benefits for you. Breathing can nurture your body, center you, and rebalance you. When you start harnessing the power of your breath, you're going to feel incredibly better than you do right now. Patrick McKeown , an author, educator and one of the world’s leading breathing re-education experts, has researched breathing for more than two decades. Listen to more: Shut Your Mouth! Nose Breathing Improves All Your Body Systems – Patrick McKeown – #835 James Nestor , a San Francisco-based science journalist, author, surfer, free diver, adventurer, and speaker, set out on a decade-long quest to find out where our breathing went wrong—and how to fix it. Listen to more: Breathing Essentials That Will Change Your Life – James Nestor – #751 WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Support Your Body’s Natural Repair Mechanisms: https://eng3corp.com/DAVE/ Must-Have Magnesium: https://magbreakthrough.com/DAVE , use code DAVE10 to get a 10% discount Meat Sticks! All the Good Stuff-No BS: https://paleovalley.com/DAVE , use code DAVE to get 15% off your first order See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 4, 2022

SPECIAL OFFER FOR LISTENERS OF THE HUMAN UPGRADE: Go to https://www.oneskin.co and use code DAVE15 to get 15% off your first-time purchase . IN THIS EPISODE OF THE HUMAN UPGRADE™... …you’re listening to a new Upgrade Spotlight series based on what you told me you wanted to hear on this podcast. On one Friday each month, these shorter episodes will feature guests who’ll get right into useful information in a Q&A style. You’ll find out how to improve your energy and upgrade your performance. You’ll also get the latest knowledge about powerful tools and technologies that allow you to change your biology and the environment around you. Introducing OneSkin ! During this Upgrade Spotlight, you’ll learn about new products designed to target skin aging at the molecular level and promote skin and body health. You’ll also find out the science behind OneSkin’s formulas and why they are considered “daily topical supplements.” They can help you maintain functional and resilient skin as you age. OneSkin topical supplements are powered by a proprietary peptide: OS-01, which decreases the accumulation of aged/senescent (zombie) cells in the skin. By targeting the major driver of skin aging, OS-01 has been scientifically proven to: • Repair cellular damage, including UV damage • Increase epidermal thickness • Improve barrier function • Increase the activity of genes associated with collagen, hyaluronic acid, and elastin production • Reverse the biological age of skin “So this peptide has a very interesting profile because it's small enough to penetrate and it's super safe,” explains Carolina Reis Oliveira, Ph.D., scientist, CEO and co-founder of OneSkin. “There is no toxicity, no irritation. We've done all the recommended studies by FDA for personal care products, and, has this beautiful effect of reducing the accumulation of senescent cells, and also reduces the release of inflammatory markers, and increase the production of hyaluronic acid, elastin and collagen. So, in the end, there's a molecule that has all these attributes that's very important for healthy skin, overall.” Another exciting part of this peptide work includes MolClock, the first skin-specific molecular clock, capable of reliably and accurately determining the biological age of skin. This was created by OneSkin’s team of female PhD-level longevity scientists as part of its research and development platform. Carolina relocated from Latin America to Silicon Valley in 2016 to co-found OneSkin and lead the development of the company’s disruptive skin rejuvenation technologies. She holds a Ph.D. in Immunology, along with degrees in biochemistry, stem cell biology and tissue engineering. Her team of co-founders includes three other female scientists with additional expertise in skin regeneration, bioinformatics, genomics, immunology and molecular biology. Among them, they’ve invented numerous patents and have published nearly 100 peer-reviewed papers in scientific journals. This episode explores exciting new information about improving skin health at the molecular level for the long-term. When you do that, your body will be more equipped to defend itself from environmental stressors and aggressors, especially with age. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 3, 2022

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Capture Life Force Energy : https://leelaq.com , use discount code DAVE10 to get 10% off sitewide Skin Health and Healing: https://alituranaturals.com/shop/ , use code DAVE20 for 20% off storewide Business Growth With SEO: https://www.stephanspencer.com , get a FREE consultation SPECIAL OFFER FOR LISTENERS OF THE HUMAN UPGRADE : Go to https://pendulumlife.com and use promo code " DAVEVIP " to get an exclusive discount. IN THIS EPISODE OF THE HUMAN UPGRADE™... …you’ll learn about emerging science that points to the effects of sugar on your gut microbiome and metabolism and the connections between sugar, your mental acuity and longevity. Biochemist and molecular biologist Colleen Cutcliffe, Ph.D., continually searches for new ways to improve your gut health and help you live longer. As CEO and co-founder of Pendulum Therapeutics , she works to turn scientific discoveries into real products that hack and heal your microbiome and its associated body systems. At Pendulum, her team identifies and isolates new bacterial strains then combines those new strains to create unique probiotics. “We really worked hard on ways to modulate post-postprandial glucose spikes through the microbiome,” Colleen says. The result? Pendulum’s Glucose Control lowers blood glucose spikes by 33 to 34% for people with type 2 diabetes. “What we didn't realize was how many people who don't have type 2 diabetes were going to end up benefiting from it.” This conversation homes in on sugar management and a broad range of research that’s exploring what you can do about managing your glucose to keep up your mental acuity (less brain fog, sharper thinking) and live a longer life. Science has discovered that as you age: You have reduced ability to metabolize sugar. Your microbiomes become less diverse and depleted of certain key strains that are important for sugar metabolism. If you improve glucose control, you see reduced neuronal inflammation and improved cognition. In the past decade, especially, sugar dominates a lot of the conversation around diet and health. It’s been studied, substituted, moderated, restricted and demonized. With that type of focus, you lose the bigger point. “You can't completely cut out sugar,” Colleen says. “You do need sugar. Not all sugar is bad for you all the time. Every cell in your body, except for your colon cells, need glucose in order to survive, in order to replicate, in order to perform functions. All of the things that allow you to be a human being require some amount of sugar." She wants you to know what’s happening to cause the change in metabolic processing as you age and what you can do about it, like: How to understand your blood glucose range and what fluctuations mean. How to track your blood glucose and what to do about peaks and dips. How to improve your focus, sharpness and mental endurance through diet and fitness. “I'm a scientist, so I'm always going to say more data is better,” Colleen explains. “[Especially] when you're trying to make improvements and you're making these micro-adjustments in your life, and you want to understand what impact are they having.” See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Jun 1, 2022

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Hydrate with Electrolytes: https://DrinkLMNT.com/DAVE , get a free LMNT Sample Pack with 8 single-serving packets for the cost of shipping ($5 for U.S. customers) Control Blood Glucose: https://pendulumlife.com , sign up for membership to get monthly supply delivery, use code DAVE20 to save $20 on your first shipment Mattress Temperature Tech: https://www.eightsleep.com/dave , use code DAVE to save $250 on the Pod Pro IN THIS EPISODE OF THE HUMAN UPGRADE™... …you’ll learn how to connect the principles of self-coaching to biohacking. You may already be doing some things, but this topic will help you fine-tune your approach in simple, yet powerful, ways. High performers typically know the value of coaches: experts who can train them and guide them toward goals. But what if you could become your own coach? Podcast guest Jason Goldsmith emphasizes the value of combining the mental and physical aspects of human performance. He knows, too, that it’s important to learn to coach yourself to achieve any kind of life success you go after. Self-coaching doesn't mean you do it all on your own, it means that you take charge of yourself, for yourself. This episode brings these concepts together so you can be in charge of yourself and be confident and purposeful when making decisions. A globally recognized performance coach and founder of Goldsmith Performance, Jason’s best known for his work with golfers, from junior, to amateur to professional skill levels. He also coaches athletes from other major sports, as well as Fortune 500 executives. He’s distilled his knowledge and partnered with David Novak, cofounder & former CEO and Chairman of Yum! Brands (owner of 45,000+ restaurants) to present sports and business coaching for high performance. They’ve created a practical guidebook for you to learn how to be your own best coach: “ Take Charge Of You: How Self Coaching Can Transform Your Life and Career .” This conversation covers strategies to develop an understanding of who you are and what drives you. “That is a crucial part of choosing your SBT (single biggest thing): it should feel big, important, impactful, even aspirational,” Jason says in his book. “There is a difference between setting a goal and choosing a destination.” You can outline a process with that knowledge that sets you up for success. And then add in something you may not have considered: “Joy is a critical ingredient, and I don't think enough people have enough joy in their day-to-day life,” Jason says. “It’s really important for people to know what it is that brings them joy and what are the things that diminish their joy. So, if I was able to biohack my day, what are the things I do every single day that make me feel the best possible version of myself? But then what are the things that get in the way of that joy? And then how do I eliminate those joy blockers and have more of those joy builders?” You’ll find out how in this episode! “Take Charge of You” includes do-it-yourself lessons, stories, tips, and questions to ask yourself to track your personal growth and professional development. You can follow this blueprint for self-coaching, no matter what your goals may be. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 27, 2022

Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month. Drugs that cut down cancer risk by 61% aren't really drugs. Take the right type of Vitamin D for the most benefit. Stressing cells in the sauna could help reverse neurological disease. A new discovery in brain communication and function. Making stem cells younger in less time. Active brown fat could be a marker for pre-diabetes. EPISODE SPONSOR: Infrared Sauna Benefits with Sunlighten. https://www.sunlighten.com/DAVE. Save up to $600 on your sauna purchase! Mention code "DaveAsprey" for discount. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 27, 2022

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Skin Health & Healing: https://alituranaturals.com/shop/ , use code DAVE20 for 20% off storewide Digestion & Immune Function: https://justthrivehealth.com , use code ASPREY to get 15% off Business Growth With SEO: https://www.stephanspencer.com , get a FREE consultation IN THIS EPISODE OF THE HUMAN UPGRADE™... …you’ll learn how biological age, rather than chronological age, is the primary risk factor behind diseases like cancer, heart disease, diabetes, strokes, even Alzheimer’s. Scientific discoveries show chronological aging may be written in the epigenome, those chemical tags attached to your DNA that control the way DNA operates. We’re finding out more about both types of aging because of scientists like Morgan Levine, Ph.D., a leading voice in the field of aging and longevity science. She focuses her research on the science of biological aging, emphasizing health span over lifespan. “If you take the difference between someone’s biological age and chronological age, it should predict the things we care about, the actual things we're trying to prevent—so death, disease,” she says. She’s an assistant professor of pathology and the Director of the Laboratory for Aging in Living Systems at Yale University School of Medicine. Her team looks at using bioinformatics to quantify the aging process and test how lifestyle and pharmaceuticals alter the rate of aging. She’s also a founding Principal Investigator at Altos Labs , a biotech company that focuses on cellular rejuvenation programming to restore cell health and resilience. Today, she’s going to talk about the science of aging and longevity explored in her new book, “ True Age: “Cutting-Edge Research to Help Turn Back the Clock .” Three main drivers—health behaviors, recent stressors and adversity, and genetics—determine your biological aging. She shares how to measure your own biological age and why you should track your aging regularly. This conversation gets into topics and makes them make sense for your own aging, like: Epigenetics & epigenetic clocks DNA methylation & telomeres Cell lifespan Ageotypes (molecular assessment of aging) Phenotypic age The “Ceiling” effect The “CALERIE” trial Nutrition & aging (plants, fasting, ketosis) Fitness & aging (energy & brain health) Rest & relaxation (sleep & biological programming) Morgan gives great takeaways on how you can make lifestyle changes to maintain your youthfulness—both inside and out—with low-risk, data-driven biohacking. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 24, 2022

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Trigger Autophagy: https://spermidinelife.us/dave , use code DAVE25 for 25% off your first month’s order Meat Sticks! All the Good Stuff-No BS: https://paleovalley.com/DAVE , use code DAVE to get 15% off your first order Sleep Better on Natural Memory Foam: https://myessentia.com , use code DAVEVIP to get an exclusive discount IN THIS EPISODE OF THE HUMAN UPGRADE™... …you’re going to find out why you’re missing 50% of your life to fractured attention and distraction and what it’s doing to your brain. Podcast guest Amishi Jha, Ph.D. , a neuroscientist and professor of psychology at the University of Miami, researches how people pay attention. She co-founded the Contemplative Neuroscience for the Mindfulness Research and Practice Initiative at the University of Miami and serves as its director. For more than 25 years, she’s researched the science of attention through intensive work with the U.S. Military, first responders, medical professionals, business leaders, and elite sports teams. She’s found that attention Is both your superpower and your kryptonite. As a superpower, attention allows you to time-travel in your mind (future and past), highlights what’s important, helps you problem solve, and shuts out distractions, she explains in her book, “ Peak Mind: Find Your Focus, Own your Attention, Invest 12 Minutes a Day .” When attention is compromised, it’s your kryptonite because it impacts your cognitive function, social engagement, and emotional balance, she points out. The three main forces that degrade attention include, 1) the amount of stress you’re under (and how you’re managing it); 2) being in a crappy mood; and 3) threats real or imagined. And when your attention gets fractured, you often default to tactics that fail to pull it back together. Amishi’s got great insights in her book that allow you to understand why this happening. When you know what’s going on, it's easier to find your focus. It’s absolutely possible to change your brain to become more attentive, present, and productive through mindful techniques and daily focusing practices. Amishi’s research shows that mindfulness gives you a sense of control over your mind and allows you to stop negative thinking before it hijacks your brain and body. The type of mindfulness practice you choose isn’t as important as how consistently you actually do it. The minimum effective dose equals 12 minutes a day, five days a week. Listen on to a conversation that gives you practical tips on how to re-capture your attention, train your brain and perform at your peak. More about Amishi Jha, Ph.D.: Amishi earned a Bachelor of Science degree in Biological Psychology then went on to earn a Ph.D. in Psychology (Cognitive Neuroscience) from the University of California–Davis. She completed post-doctoral training at the Brain Imaging and Analysis Center at Duke University in functional neuroimaging. She leads research on the neural bases of attention and the effects of mindfulness-based training programs on cognition, emotion, resilience, and performance. Her work has been featured at NATO, the World Economic Forum, and the U.S. Pentagon. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 21, 2022

In this Episode of The Human Upgrade™...​ … Dave talks with Sean Plotkin about changing up his current biohacking routine to get even better results. You’ll find out how to maintain a high quality of life amid the “hustle” that can take up a lot of your everyday life. In his mid-40s, Sean’s doing a lot to improve his energy, keep his body strong and stay ahead of aging. But, he says, the weight keeps creeping up and he’s concerned about his thyroid function. He has an intense weekly exercise routine and could use some help with nutrition before and after his fitness sessions. He also wants to tackle sleep, believing his isn’t as optimal as it could be. He’s doing a lot of things right, including: supplementing with glutathione, using ozone, wearing a continuous glucose monitor, cooling his sleep with an Ooler Sleep System , tackling how he feels with Hapbee , managing stress and performance with NuCalm , upgrading his brain at 40 Years of Zen , and investing in a hyperbaric chamber and sauna for home use. In this “Interventions With Dave” episode, Dave examines what Sean’s doing, what’s working or not, and what he can do to reach his peak performance consistently. They break down: Nutrient availability (No. 1, energy; No. 2, protein; and No. 3, carbs) Blood glucose and insulin resistance Cortisol and stress Hormones Cognitive function Nutrition Pre-diabetes Fatty liver Inflammation Cold therapy Cholesterol Metabolic health Brain health And much more! Sean’s already got great awareness, tools and data to work with. Along any journey, it takes some experimentation—and time—to find that sweet spot that makes you feel like a million bucks. Note: The "Interventions With Dave” recommendations are designed to help you upgrade yourself and your biology so you can perform better at everything you do. They are not, however, a substitute for advice or treatment by a trained medical professional that may be needed for specific health conditions, illness or injury. Don't miss the previous episodes in the Interventions With Dave series: Hacking Weight Loss Resistance #930 Hacking Thyroid, Autoimmunity & Aging #918 Hacking Inflammation #915 Hacking Your Gut Microbiome #908 Hacking Menopausal Weight Gain #904 Hacking Eyesight #895 See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 20, 2022

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Nature’s Nootropic: https://trukava.com , use code DAVE15 to get 15% off NAD+ for Brain Health: https://innovativemedicine.com/DAVE and save 20% Minerals for Cell Function: https://www.beamminerals.com , use code DAVE20 to get 20% off SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://www.radicalrootsherbs.com/ , use code “ DAVE15 ” to save 15% off Radical Roots full-spectrum hemp and Chinese herbs products. IN THIS EPISODE OF THE HUMAN UPGRADE™... …you’ll learn about all things CBD, hemp and THC: what current research says, why quality matters, and how to get real results. Paired with particular Chinese herbs, the benefits to you increase even more. In the last few years, CBD was a trend, then the market got saturated, and then people said: “I tried CBD and nothing happened.” That’s unfortunate, because experts like acupuncturist, herbalist and Chinese Medicine practitioner Dr. Chloe Weber know exactly what works—and how. There are four main ways hemp supports the mind and body, and this conversation gets into the mechanisms of them all: Anxiety and stress, GI support, immune support, and pain management/inflammatory disorders. You’ll also find out: The differences between full spectrum (with 0.3% THC) vs. isolate vs. pharmaceutical cannabis. How your body’s endocannabinoid system works and why it’s your master regulator. What endocannabinoid deficiency means for your body. How to take CBD and how long it takes to experience its effects. How pairing CBD with Chinese herbs can benefit your body and brain, and power your performance. What to look for in high-quality hemp products. How to maneuver through cannabis strains and THC potencies. How to decide between CBD oils, capsules, topicals for your particular health needs. Common misconceptions about and censorship of CBD. What new cannabinoids are coming onto the scene, like CBG and CBN. Chloe founded Radical Roots Herbs, a company that offers full-spectrum hemp product and also combines CBD with Chinese herbs to boost the power of both. “By calming the nervous system and supporting our endocannabinoid system,” Chloe says, “we're actually able accept, absorb and process the Chinese herbs in a more dynamic way." See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 17, 2022

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Support Skin Health and Healing: https://alituranaturals.com/shop/ , use code DAVE20 for 20% off storewide Support Digestion and Immune Function: https://justthrivehealth.com , use code ASPREY to get 15% off Support Your Body’s Natural Repair Mechanisms : https://eng3corp.com/DAVE/ IN THIS EPISODE OF THE HUMAN UPGRADE™... … I will teach you everything you would ever want to know about before surgery, during surgery and after surgery, so that you come in strong, you have a better surgical experience, and you recover way faster than you're supposed to. Research shows that if you live in America, you’re likely to have an average of seven surgeries in your lifetime. Wouldn’t you want to know how to go in at your best so you can recover at your best? This was my thinking when I went under the knife last year. In the hours and days that followed, I blew my doctor’s mind. He had never seen a recovery like mine. As the Father of Biohacking, I never shy away from an opportunity to blow the lid off what we think is biologically possible. And then I share what I’ve found with the world. In Heal with Dave, my new documentary, you’re going to learn all of the methods I used to heal without pain and recover to the fullest and beyond. I’ll teach you how. If this sounds interesting to you and you want to know what to do to have control of your biology at a time when frankly, a lot of people take quite a while to recover and there's increased risk of all kinds of bad things like infections, systemic issues, just not healing very well and building strong tissues, go to daveaspery.com/heal . Watch the documentary, use the resources. It's my gift to you! “Heal with Dave” Documentary: https://daveasprey.com/heal/ Ali Sadrieh, DPM at Evo Foot: https://www.evofoot.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 13, 2022

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Control Blood Glucose: https://pendulumlife.com , sign up for membership to get monthly supply delivery, use code DAVE20 to save $20 on your first shipment Tasty Keto Bread & Chips: https://www.uprisingfood.com/DAVE , use code DAVE to get $10 off the starter bundle Business Growth With SEO: https://www.stephanspencer.com , get a FREE consultation IN THIS EPISODE OF THE HUMAN UPGRADE™... … you’ll learn why developing your attributes may be more important than skills when it comes to getting more out of yourself. Attributes are wired into your internal circuitry, always running in the background, says Rich Diviney. You’re born with attributes. They’re elemental and considered innate traits—not to be confused with personality traits. Rich, a retired Navy SEAL commander, bestselling author, and leadership and human performance expert, explains how attributes determine how you absorb, process, and respond to the world around you. By knowing this, you’ll be able to assess your own attributes and put them into action with SMART steps. In his book, “ The Attributes: 25 Hidden Drivers of Optimal Performance ,” Rich shows you how mindset, optimism and becoming uniquely resilient to stress can help you become a better human. His approach identifies core attributes needed for success in personal or professional tasks. His ability to choose the right people to be in elite performance groups—like the U.S. Navy SEALs—could be considered a superpower. As the officer in charge of training for a specialized command, Rich was part of the SEAL selection process. He pared down a group of exceptional candidates to a small cadre of the most elite optimal performers. How did he do it? By looking at attributes . It’s Rich's belief that SEALs are not born extraordinary. Instead, they’ve mastered their own mindset to get the most out of their innate abilities to make themselves extraordinary. He believes we all have the power to do this. In “ The Attributes ,” you’ll find examples of attributes within five distinct categories plus a couple more that don’t fit so neatly: Grit, Mental Acuity, Drive, Leadership and Teamability. So, what are attributes and how are they different than skills? “A lot of times we get seduced by skills, and we don't think about attributes,” Rich says. “And the reason is very simple: skills are not inherent to our nature. They're very visible, which means they're very easy to assess, measure and test and you can put scores around them and stats around them. … Attributes are inherent to our nature. We're all born with levels of adaptability and situational awareness and resilience. Attributes don't dictate our behavior or director behavior; they inform our behavior.” See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 11, 2022

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Track Blood Glucose : https://www.levelshealth.com/DAVE , sign up for the Beta group Kickstart Autophagy: https://timelinenutrition.com/DAVE , use the code ASPREY10 to get 10% off any plan Mattress Temperature Tech: https://www.eightsleep.com/dave , use code DAVE to save $250 on the Pod Pro IN THIS EPISODE OF THE HUMAN UPGRADE™... …you’ll learn that to be a high performer, you’ve got to have radical confidence to achieve whatever goals you set for yourself. Today’s guest, Lisa Bilyeu, explains how real confidence is an inside job, not something you gain from outside validation. When Lisa co-founded Quest Nutrition, she was a self-professed housewife boxing protein bars in her living room. The company grew 57,000 percent in its first three years and became a billion-dollar brand. Her learning curve was steep and fast and filled with things she didn’t know how to do—yet. She went on to co-found (with her husband, Tom Bilyeu) and serve as president of Impact Theory Studios. It’s a digital-first studio that produces entertaining original content focusing on themes of empowerment. That content has been viewed over half a billion times by a global audience. Lisa oversees in-house development of projects focused on female-driven content for multiple platforms. She hosts the digital series, “ Women of Impact .” In her first book, “ Radical Confidence: 10 No BS Lessons on Becoming the Hero of Your Own Life ,” she shares her journey from a housewife to successful entrepreneur with relatable lessons, anecdotes, and lots of humor. She explains how the “Purgatory of the Mundane” is even more dangerous than hitting rock bottom. She dishes tough love for those of you who are stuck in mind loops that hold you back. From ditching the fairy tale to getting off the couch to putting on goggles when the shit hits the fan, Lisa’s got realistic tips to get you moving. An important part of that momentum is setting boundaries: material, physical, and mental and emotional. She shows you exactly how. She also suggests a fresh perspective on a few things that can help you build “radical” confidence: Manage the voice in your head Set clear boundaries Learn from your mistakes Keep your goals top of mind Maintain self-awareness around your emotions and triggers See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 7, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... …you’re listening to a new Upgrade Spotlight series based on what you told me you wanted to hear on this podcast. On one Friday each month, these shorter episodes will feature guests who’ll get right into useful information in a Q&A style. You’ll find out how to improve your energy and upgrade your performance. You’ll also get the latest knowledge about powerful tools and technologies that allow you to change your biology and the environment around you. Introducing Xero Shoes ! During this Upgrade Spotlight, you’ll learn how minimalist footwear reduces injury, improves foot strength and supports healthy feet. You’ll learn that getting grounded is a good thing. Today’s guest—serial entrepreneur Steven Sashen—is a competitive sprinter. He knows the mechanics of human feet. He also knows what it feels like to move in shoes that suck. So, he and his wife, Lena Phoenix, founded the footwear company Xero Shoes. They ran headlong into shoe history and shoe science to intentionally create “a MOVEMENT movement” of people with happy, healthy, strong feet in addictively comfortable footwear. “A quarter of the bones and joints of your whole body are in your feet and ankles,” Steven says. “They're supposed to bend and move and flex just like any other joint. If you're wearing shoes that don't let them do that, that function tries unsuccessfully to move into your ankle, your knee, your hip and your back joints. Those joints aren't built for those micro motions that keep you balanced, that give you agility and mobility.” Your feet, and by design the rest of your body, know something’s off with cushioned shoes. So does Steven. “The value of natural movement, the importance of foot health, and all the things that relate to foot health got me going,” he says. “But what really catalyzed it was discovering that what the footwear industry has been doing for 50 years is lying to people – selling people on ideas that they know don't work, but they can't pull back. They can't tell a different story, because they've been promoting this story for so long about arch support, motion control, padding, cushioning, etc.” Research published by the American College of Sports Medicine in 2021, “Stepping Back to Minimal Footwear: Applications Across the Lifespan," showed that minimal footwear leads to improved musculoskeletal health across your lifetime. “It’s all about natural motion,” Steven explains. “Our ancestors didn't have a problem being on their feet all day, every day. It wasn't because they're different from us, it was just that they got used to using their feet correctly. We can still do that any day, anytime, any of age.” CHECK OUT XERO SHOES and the 5,000-MILE SOLE WARRANTY! U.S.: https://xeroshoes.com and EU: https://xeroshoes.eu See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 6, 2022

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Complete Spectrum Hemp + Chinese Herbs: https://radicalrootsherbs.com/DAVE , use code DAVE to get 10% off Meat Sticks, Apple Cider Vinegar and More Good Stuff: https://paleovalley.com/DAVE , use code DAVE to get 15% off your first order Biostack for High Performance: https://vatellia.com , use code DAVE2022 to save 10% or subscribe and save 15% + receive a free bottle of Kale Buster IN THIS EPISODE OF THE HUMAN UPGRADE™... …you’ll find out why you’re tired, how to fix it and ways to increase your energy. Fatigue is a hidden epidemic, with chronic fatigue syndrome being the most severe end, but most people (in the U.S.) are experiencing some level of being flat-out tired as hell. Guest A ri Whitten, Ph.D. (Cand.), CES, PES , says that as a culture, we have normalized fatigue. In his newest book, “ EAT FOR ENERGY: How to Beat Fatigue, Supercharge Your Mitochondria, and Unlock All-Day Energy ,” he explains that 5.4 million adults in the U.S. have been diagnosed with chronic fatigue syndrome (the most severe case of fatigue). However, the true fatigue epidemic affects 50 to 100 times more people. This episode’s discussion gets right into the role of mitochondria in human energy. Ari’s research (420 citations in “Eat for Energy”!] is clear. The cause of fatigue is mitochondrial dysfunction, he says. And the biggest factors that affect your mitochondria include: Circadian rhythm dysregulation and poor sleep Carrying too much body fat and too little muscle mass Poor gut and microbiome health Blood sugar dysregulation Nutritional toxicities and deficiencies Neurotransmitter and hormone imbalances So what can you do to increase your energy currency? A lot, as it turns out. When you understand factors like resilience, cell defense, nutrition and supplementation, you’re on your way to better energy. In this conversation, you’ll learn: what’s causing the dysfunction in your mitochondria and how you can repair these critical energy cells. strategies that will double your energy levels. 7 top supplements (and more) that help get your mitochondria back on the energy track. Ari has been studying and teaching natural health science for more than 25 years. He went through his own battle with chronic fatigue that inspired his obsession with energy. For the past seven years, he's focused specifically on improving human energy. His education and work in this area touches on critical aspects of human health from nutrition to physical training, to light science, to psychology, and more. He created The Energy Blueprint science-based lifestyle programs that target brain energy and mitochondria. He also hosts The Energy Blueprint podcast that features world-wide experts on the subject of understanding fatigue and how to get more energy. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

May 4, 2022

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Sleep Better on Natural Memory Foam: https://myessentia.com , use code DAVEVIP to get an exclusive discount Must-Have Magnesium: https://magbreakthrough.com/DAVE , use code DAVE10 to get a 10% discount Control Blood Glucose: https://pendulumlife.com , sign up for membership to get monthly supply delivery, use code DAVE20 to save $20 on your first shipment IN THIS EPISODE OF THE HUMAN UPGRADE™... … you’ll meet a holistic neurosurgeon who’s evolving spine care away from cutting. Dr. Marcella Madera’s integrative approaches to spine problems pair science with holistic healing modalities. This means way better healing for you. Dr. Madera’s innovations in spine treatments include the “Aqua Method,” where photobiomodulated platelet rich plasma meets functional tissue mobilization and movement. You’re going to get exciting new information about this effective form of regenerative medicine and find out if this treatment may be right for you. “It's a very nuanced discussion,” says Dr. Madera. “It's very patient specific. It's very injury specific.” “The term Aqua really gives a description of what we're trying to create in the body and that is more fluidity,” she explains. “And also, water, aqua, is pure. It’s intense at times, depending on the form. And it is soothing at times, depending on the form. And that is how our treatment goes.” Dr. Madera’s four-part system includes: Reveal, Restore, Revitalize, Revel. You could benefit whether you have an old or new injury, or chronic pain. During this episode, she explains how each part is interconnected and helps you heal your spine, or even knee, problems. The Aqua Method’s three-day immersive experience includes a full team of experts focused on your biology, your energy and your state of mind. Dr. Madera, a board-certified neurosurgeon, trained extensively in conventional medicine. Her expertise in spine care includes surgical treatments, approaches, and techniques for degenerative spine disease, spine tumors, and degenerative deformity. She started a private practice in in Austin, Texas where she combines her technical spine care with stem cell treatments and holistic modalities like herbs, energy modalities, Chinese healing practices, autogenic training and diet modification. SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Get a $1,000 discount on the Aqua Method at Austin Integrative Spine in Austin, Texas. Call the clinic at 512-817-4600 and mention discount code DAVEASPREY. More about Dr. Marcella Madera: She’s experienced in open surgery, minimally invasive surgery, endoscopic spine surgery, and regenerative/stem cell procedures. She’s been an assistant professor of Surgery at the University of Texas at Austin Dell Medical School. She also travelled throughout Europe and the U.S. to learn progressive endoscopic techniques and regenerative medicine practices. She completed a Spine Fellowship and faculty instructorship at Johns Hopkins School of Medicine. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 29, 2022

Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month. GlyNAC (glycine and N-acetylcysteine) can correct glutathione deficiency, oxidative stress, mitochondrial dysfunction and mitophagy abnormalities to help you live longer. Moms and dads think — and react — differently to newborn baby smells. Clock and Cycle factors control circadian rhythm and protect your eyes as you age. Oleic acid produced in the brain helps regulate memory, learning, and mood; promotes neurogenesis; and increases cell proliferation. EPISODE SPONSOR: The Eng3 NanoVi device helps repair oxidative stress damage and support the body’s natural repair mechanisms. https://eng3corp.com/DAVE/ . Learn more: The Anti-Aging Science Behind the NanoVi Device – Rowena Gates & Hans Eng – #416 . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 28, 2022

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Nature’s Nootropic: https://trukava.com , use code DAVE15 to get 15% off NAD+ for Brain Health: https://innovativemedicine.com/DAVE and save 20% Support Immune & Digestive Health: https://justthrivehealth.com , use code ASPREY to get 15% off IN THIS EPISODE OF THE HUMAN UPGRADE™... …you’ll learn that one of the major life upgrades you can make includes your relationships. Personal development expert Gary John Bishop doesn’t buy into mainstream notions of what makes a happy relationship. Not 50/50 effort, not compromise, not molding yourself into what your partner wants. It’s just you and some hard truths. What this episode is not about; Blame or providing communication tips How to change or cope with your partner and personality types Healing past trauma or understanding fear of commitment Instead, you’ll get the ingredients to creating a real, lasting and profound connection with another human being. “There's some, again, cold truths that you have to face and then really have to start to take on,” he says, “but in a way that it's not always going to go your way. You're not always going to get this thing flowing the way you would want it to go, but your job is to keep bringing yourself to this phenomenon in a way that's consistent with you, who you are, what you're about. And powerfully managing all that you might do to undermine it.” Gary, the New York Times bestselling author of the Unfu*k book series, uses an “urban philosophy” approach that’s both simple and enlightening. In his latest book, “ LOVE UNFU*kED Getting Your Relationship Sh!t Together ,” he puts the focus on relationships. “The quality of your relationships dictates the quality of your life,” he says in “LOVE UNFU*kED.” This conversation gets right to the heart of what you can do to make changes that stick in all areas of your life. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 26, 2022

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Gifts for Mother’s Day – or Any Day: Give the sensation of a hug, deep relaxation and better sleep: https://balooliving.com/dave , use code DAVE for a special discount Health Upgrades with Custom Lab Testing and Your Own Data: https://get-base.com/DAVE , use code DAVE to get 20% off your first month of membership Meat Sticks, Apple Cider Vinegar and More Good Stuff: https://paleovalley.com/DAVE , use code DAVE to get 15% off your first order IN THIS EPISODE OF THE HUMAN UPGRADE™... You’ll be part of a candid conversation about choice and freedom. And, why it’s important to be able to make a living in your chosen line of work without restriction or judgment. That’s just part of being a better-performing human. Guest Allie Rae , a wife, mother, retired nurse and Navy veteran, shares her unusual entrepreneurial journey within the adult sex entertainment industry. It may be a different topic than you expect on this show, but it’s a look at innovation opening up alternative ways of doing business outside restrictive Big Tech. She’s CEO of a brand-new online adult platform called WetSpace. You may have heard about or know of the OnlyFans platform. WetSpace is similar, but not direct competition. Allie Rae saw a problem with payment systems and banking restrictions and set out to find a solution. “At this point, this is no longer a hobby, it's a business for me,” Allie Says. “And as any business in any industry, you want to protect your business and provide stability and have long-term prosperity.” We get into some cool topics: Why Allie Rae created WetSpace; How cryptocurrency fits into her plans; The influence of Big Tech; and How advocacy—not regulation—can guide the growth of the adult sex industry. Today’s show looks at personal choice and freedom—both yours and other people’s. It challenges stigma, advocates for better systems of work, and supports creativity and business acumen. it's important that we think about both sex, because that's one of those big things that nourishes us, and also think about what's going on in the world around us, that environment that controls your biology. It matters that you’re able to choose what to do to and with your body, your energy, and your time. You get to choose to live your values—and so does everyone else. Even if you don’t agree. Being kind and respectful goes a long way in creating communities that allow you to be the highest performing human you want to be. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 23, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... … Dave talks with Diane Closser about weight loss resistance. You’ll find out how unexpected and insidious factors–both internal and external–may be affecting your body systems. That dysregulation can cause your body to hold onto excess weight. Diane Closser knows a lot about chemicals. She’s a chemist by profession and works as a Certified Lubrication Specialist and Certified Reliability Leader at a Division of General Motors. She also has a personal history of mold and heavy metal exposure, e.g., bought fixer-upper 1972 house, played with Mercury as a kid, worked as a wet bench chemist analyzing heavy metal production products, and worked in tire industry. She’s been on a journey to wellness for several years that’s included a search for real health solutions. There have been some wins: In 2020, she became particularly sensitive to chemicals, perfume, and laundry detergent. She says that ozone therapy cured her of her sensitivity and reversed her autoimmunity. And some setbacks: Her health deteriorated when husband was diagnosed with a brain tumor in 2011. She also had her house treated with Chlorine dioxide; did low-dose allergen therapy and low-dose immunotherapy; and completed chelation therapy. Through it all, she’s experienced a frustrating weight loss resistance. She says she’s “been on every diet and med known to man” since her teenage years. Now in her mid-50s, she’s looking forward to a retirement that includes sailing and bringing tap, jazz, and ballet classes to senior citizens around the country. She wants to improve her health and have the energy to make her plans a reality. In this “Interventions With Dave” episode, Dave and Diane look at her health concerns through a new lens. They examine possible causes of her inability to shed excess weight and discuss actionable next steps. Calorie counting Eating too little Environmental toxins Chemical sensitivities Mold Ozone Histamine Mast cells Metal toxicity and chelation therapy Brain fog Thyroid Testosterone in females Mycotoxins Detox pathways Collagen Note: The "Interventions With Dave” recommendations are designed to help you upgrade yourself and your biology so you can perform better at everything you do. They are not, however, a substitute for advice or treatment by a trained medical professional that may be needed for specific health conditions, illness or injury. Listen to the Interventions With Dave series and don’t miss the “Links & Resources” section below for specific information. Hacking Thyroid, Autoimmunity & Aging #918 Hacking Inflammation #915 Hacking Your Gut Microbiome #908 Hacking Menopausal Weight Gain #904 Hacking Eyesight #895 See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 22, 2022

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Get Grounded with Better Foot Function: https://www.vivobarefoot.com/us/daveasprey , use code ASPREY20 to get 20% off your first order and access to the VHealth Barefoot Movement online courses Mattress Temperature Tech: https://www.eightsleep.com/dave , use code DAVE to save $250 on the Pod Pro Isometrics for Cardiovascular Health : https://www.zona.com , use code DAVE2022 to get $150 off the Zona Plus IN THIS EPISODE OF THE HUMAN UPGRADE™... …you’ll learn how a trainer of superheroes and superstars combines core principles of fitness, nutrition, structure and balance. Magnus Lygdbäck, a Swedish health and wellness expert, entrepreneur, and lifestyle coach, joins the show to discuss powering your life in ways that most benefit your health and energy. For more than 20 years, he’s trained some of the world’s most recognizable actors, musicians, athletes, artists, and high-performance business entrepreneurs. Musicians like pop stars Katy Perry, Dua Lipa, Harry Styles and Britney Spears. Actors like Gal Gadot for Wonder Woman 1984 ; Alicia Vikander, for Tomb Raider ; Ben Affleck, for Justice League; and many more. He designed Alexander Skarsgård’s incredible transformation for the lead role as a Viking Berserker in the brand new movie, The Northman . Even with his “celebrity trainer” title (which he doesn’t love), Magnus is quick to say, “It's not who you train, it's how you train.” His Magnus Method training philosophy embraces the “ethos of an athlete.” This all-inclusive approach to performance includes an athlete’s intensity and structure, while also maintaining balance and energy. Time-zone travel, long days of filming, rehearsals, and the constant demands on a celebrity performer’s time means examining all aspects of fueling, rest and recovery. The same applies to the everyday lives of mere mortals. He encourages being open to learning new things and seeking out discomfort so you can grow. “Look at three things,” Magnus recommends. “One, what do I like to do? No. 2, what does my body need? No. 3, what do I want to master or get better at? That should create your weekly programming.” You already know, and Magnus will remind you, that there are absolutely no life shortcuts to being the superhero of your own life. In this conversation, you’ll find out how much time to spend on your workouts (not as much as you think). “What doesn’t happen in the first hour will not happen in the second,” he says frequently. Even for superheroes. Learn more about Magnus Lygdbäck’s journey from hockey player to celebrity trainer . Find out how you can improve your own performance on Magnus’s extensive YouTube channel . Get Magnus’ superhero training programs, nutrition guides, coaching and a community of like-minded people with the Magnus Method app . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 15, 2022

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Support Immune & Digestive Health: https://justthrivehealth.com , use code ASPREY to get 15% off Meat Sticks and More: https://paleovalley.com/DAVE , use code DAVE to get 15% off your first order Trigger Autophagy: https://spermidinelife.us/dave , use code DAVE25 for 25% off your first month’s order SPECIAL OFFER FOR BULLETPROOF RADIO LISTENERS: Go to https://justthrivehealth.com . You’ll find their new line, Joot, and their new Just Calm probiotic for stress management and mood support. Just Calm features the proprietary “psychobiotic” strain BL 1714™ combined with brain-nourishing B vitamins. You’ll also find other products that tackle gut health and inflammation . Use code ASPREY to get a 15% off discount. IN THIS EPISODE OF THE HUMAN UPGRADE™... …you’ll learn about a strain of probiotics called psychobiotics. This strain shows promising effects on stress relief, anxiety, mood, sleep and other important gut-brain axis connections. Microbiologist Kiran Krishnan, Ph.D., explores the human microbiome and how it functions so you can have better gut health. He has an extensive research background in the fields of molecular medicine and microbiology. His particular expertise lies in gut commensal spore bacteria microbiology. He’s been a guest on the show before to educate listeners about probiotics and the connections between your microbiome, inflammation and immune function. This time, he’s sharing exciting research about a probiotic strain that’s tackling the gut-brain axis, called Bifidobacterium longum 1714™. Kiran says, “One really important message that I want people to really wrap their heads around and understand when we're talking about the gut-brain axis is, of course, the gut. A healthy gut is incredibly supportive to the brain. It supports the brain in a number of really important critical functions like recovery, for example, or production of serotonin and dopamine and all these important neurotransmitters, but on the other end of the spectrum, an unhealthy gut is not only not supportive, but it's arguably one of the most toxic things for the brain.” Big topics covered in this episode include: Basic mechanisms by which the gut microbiome can influence neurochemicals and brain inflammation The gut-brain connection as it relates to stress coping and mental health How cortisol and interleukin 6 drive stress response and inflammation in your whole body Variables that can cause a breakdown or dysfunction in the psychobiome Therapeutic interventions, including psychobiotics that can help correct gut-brain axis dysfunction Kiran’s great at explaining the science so you clearly understand what the studies mean and can apply new knowledge to your own biology. He also partners with Just Thrive Health on product research and development. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 12, 2022

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Mattress Temperature Tech: https://www.eightsleep.com/dave , use code DAVE to save $250 on the Pod Pro Health Upgrades with Custom Lab Testing and Your Data: https://get-base.com/DAVE , use code DAVE to get 20% off your first month of membership Vascular System Protection: https://arterosil.com/DAVE/ , save up to 45% a 3-pack to protect your blood vessels from vulnerable plaque. IN THIS EPISODE OF THE HUMAN UPGRADE™... …you’ll learn how nature, human health, and climate activism interconnect. Emma Loewe, environmental journalist and senior sustainability editor at mindbodygreen, joins the show to share how nature can restore all aspects of your health. You’ll find out how you can reap the benefits of specific nature landscapes, wherever you live or roam. You’ll come away from this episode with: Tips on how to combat stress, anxiety and burnout by being outdoors. Actions you can take to conserve the landscapes you care about. Mindset shifts that will change the way you think about the climate crisis . In her new book, “ Return to Nature: The New Science of How Natural Landscapes Restore Us ,” she’s researched the ways eight distinct nature landscapes improve your physical, mental and spiritual health. Parks & Gardens Oceans & Coasts Mountains & Highlands Forests & Trees Ice & Snow Deserts & Drylands Rivers & Streams Cities & Built Environments Emma shares research-backed ways to explore nature now and protect it for the future, including SRT (stress-reduction theory). This theory says that humans are hardwired to relax while looking at environments that have extensive views, areas to retreat, and essential resources like shade and water. “ Return to Nature ” also offers: Mindful exercises you can do in short or long chunks of time that allow you to fully experience nature when you’re in it. Additional resources about the eight natural landscapes Emma writes about. Nearly 30 pages of research references! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 7, 2022

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Kickstart Autophagy: https://timelinenutrition.com/DAVE , use the code ASPREY10 to get 10% off any plan Isometrics for Cardiovascular Health : https://www.zona.com , use code DAVE2022 to get $150 off the Zona Plus Business Growth With SEO: https://www.stephanspencer.com , get a FREE consultation SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS! Go to https://get-base.com/DAVE . Use code DAVE to get 20% off your first purchase. IN THIS EPISODE OF THE HUMAN UPGRADE™... … you’re going to learn about the engineering it takes to build a health data app. You’ll find out how data science, mathematics and predictive analysis look at how biomarkers impact overall wellness. At Base, your own data, along with deep expertise from an advisory board of functional medicine doctors, inform the algorithms. This means you get a distinctly personalized prescription on how to manage your health concerns. Guest Lola Priego, founder and CEO of Base, is an experienced software engineer and former medical student on a mission to help people better understand what is going on in their bodies. She possesses a unique combination of skills to do just that. She studied medicine before transferring to engineering at the Technical University of Madrid and earned a master’s degree in Computer Science and Artificial Intelligence at the Illinois Institute of Technology. While struggling with her own health problems, she identified major pain points in the healthcare system like lack of access to personalized health data. She created Base to solve this issue with a data-driven approach that also provides actionable diet and lifestyle recommendations. Base gets to the root cause of health concerns through analyzing biodata like hormones, nutrition, and vitamin deficiencies to get to the core of why you feel “off.” Base provides testing options that usually are not available at a primary care doctor’s office (they’re often only offered by specialists). Convenience is built into the lab testing process. Base’s blood and saliva tests gets to the root of issues like stress, anxiety, fatigue, and brain fog. Here’s what Base and its accompanying app offer you so you can take control of your own biology and make meaningful life changes: Regular testing tells you what’s going on with your biology. Your own data informs recommendations on how to improve your diet, stress, energy, sleep, and sex drive. You can track your results over time, get help from a team of online experts, and set specific health goals. Because it’s your own health data, there are privacy issues at play you have to know about. Lola explains that security and privacy are built-in design features at Base. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 5, 2022

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Strengthen Your Back, Align Your Spine: https://bodyaline.com , use code DAVE100 to save $100 Health Upgrades with Custom Lab Testing and Your Data: https://get-base.com/DAVE , use code DAVE to get 20% off your first month of membership Control Blood Glucose: https://pendulumlife.com , sign up for membership to get monthly supply delivery, use code DAVE20 to save $20 on your first shipment IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... … natural vision expert Claudia Muehlenweg shares interesting knowledge and practical solutions about how you can take better care of your eyes and improve your vision. In this longer episode, You’ll discover ways you can improve your vision through natural methods that start with root causes in your body, including nervous system regulation. You’ll explore bodywork, breathwork, rest, light and movement healing methods. You’ll find out the essential Dos and Don’ts for good eyesight. You’ll get practical suggestions for things you can do right now to offset the effects of screen time. You’ll learn how you can keep your vision sharp throughout your life span. After working to improve her own eyesight, Claudia founded Holistic Vision LLC to help others. Her work is based in the Bates Method . She focuses on finding the root cause of blurry vision instead of using symptomatic treatments like glasses, contacts or surgery that actually can make eyesight worse in the long term. She’s been teaching eyesight improvement since 2009. Her methods can improve presbyopia, myopia, astigmatism, hyperopia, strabismus, convergence insufficiency, and eye diseases such as cataracts, macular degeneration and glaucoma. She also helps people restore clarity after corrective surgeries like LASIK have worn off. Her experience as a yoga teacher brings together complementary practices like myofascial release, breathwork and bodywork that greatly influence holistic vision care and natural vision healing methods. SPECIAL OFFERS FOR THE HUMAN UPGRADE LISTENERS! Step 1 : FREE 5 Day Training “See Better in Just 5 Days” April 11-15, 2022. Click here to register. Step 2: FREE “See Clearly Without Glasses or Surgery!” live workshops. Choose one date: April 18, 20 or 22, 2022. Click here to register. Step 3 : “Naturally Clear Vision” 10-week online holistic vision improvement program. Click here to register-waitlist only. Just want a freebie? “10 Habits for Happy, Healthy Eyes.” Get the guide here. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Apr 2, 2022

SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS! Be Cool, Get Deeper Sleep: Check out the Dock Pro Sleep System at https://www.chilisleep.com/discount/HUMANUPGRADE20 . Use code HUMANUPGRADE20 to save 20%. IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... …you’re listening to a new Upgrade Spotlight series based on what you told me you wanted to hear on this podcast. On one Friday each month, these shorter episodes will feature guests who’ll get right into useful information in a Q&A style. You’ll find out how to improve your energy and upgrade your performance. You’ll also get the latest knowledge about powerful tools and technologies that allow you to change your biology and the environment around you. Introducing ChiliSleep ! During this Upgrade Spotlight, you’re going to learn about the physical and mental health benefits of cool sleep and how to hack your sleep with new bed technology. You already know about the physical and psychological effects of not getting good sleep. Whether you’re dangerously sleep-deprived or can’t stop waking up in the middle of the night, struggling to get enough sleep over time can have devastating impacts on your body and mind. Poor sleep increases a person’s risk of developing serious medical conditions, and not getting enough deep sleep increases the chance of high blood pressure; heart attack and stroke; Dementia and Alzheimer’s disease; and Type 2 Diabetes. Tara Youngblood founded ChiliSleep so people could get the coolest sleep ever. Water-based cooling helps your body settle into a just-right temperature that’s just right for you . Your core body temperature should naturally drop every night, but for lots of people for lots of reasons it doesn't. Here are a few of the good things that happen when you regulate your sleep temperature: Cooler temperatures cue your brain to release melatonin and help you fall asleep faster. Sleeping at colder temperatures improves deep sleep and increases muscle recovery. Muscle repair and growth occur during deep sleep and REM sleep stages due to the natural release of growth hormones. Tara creates technologies and apps to help you recover your sleep and your energy. She’s a trained scientist with degrees in Science and Physics who also studied traditional Chinese medicine, Ayurvedic practices, neuroscience, and psychology. She focuses on how your physical body can get better sleep and the important essential link between sleep and mental health. Get Dangerous with Dave's new Remineralized Coffee: https://dangercoffee.com Join the 8th Annual Biohacking Conference: September 2022! https://biohackingconference.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 31, 2022

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Vascular System Protection: https://arterosil.com/DAVE/ , save up to 45% a 3-pack to protect your blood vessels from vulnerable plaque. Must-Have Magnesium: https://magbreakthrough.com/DAVE , use code DAVE10 to get a 10% discount Business Growth With SEO: https://www.stephanspencer.com , get a FREE consultation SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS! Go to https://www.knowinglabs.com/DAVE . Use code DAVE to get 20% off every home test kit. IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... … you’re going to get a step-by-step guide to taking accurate labs at home. You’ll learn how to use home test kits effectively to get high-quality results. At-home test kits got more popular in the past few years as people wanted to know more about their personal health data. Knowing your data gives you the power to control your own biology. Some of the biggest value drivers of at-home labs include: Convenience, performance specificity, and being proactive rather than reactive about your symptoms. Dolce Conde co-founded Knowing Labs to support a growing community of people who want to be proactive about their health. Knowing Labs offers reliable laboratory testing directly to consumers in the convenience and privacy of their homes. The kinds of test kits available at Knowing Labs include panels for vitamin D, inflammation, sleep & stress, weight & energy, male and female hormones and wellness, and many more. If you want to use home test kits to find out more about your own data and upgrade your health, here are a few essentials to know: It’s important to choose a certified lab. Knowing Labs is a High Complexity CLIA Certified Laboratory in the State of Texas. CLIA means the Clinical Laboratory Improvement Amendments that regulate laboratory testing. All Knowing Labs testing is done in-house so they have total control over the quality and performance of the services. It’s important to understand the type of at-home test kit you have and how to collect accurate samples. This could be saliva, blood or urine, depending on the kit you choose. For blood samples, this could mean a spot, pipette or home phlebotomist visit. Conde talks about some best practices and troubleshooting tips. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 29, 2022

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Non-Tobacco Nicotine Alternative: https://lucy.co , use code DAVE20 to get 20% off your first order of pouches, gums, or lozenges Tasty Keto Bread & Chips: https://www.uprisingfood.com/DAVE , use code DAVE to get $10 off the starter bundle Franchise Opportunity: https://ownanupgradelabs.com , to check out the fitness center of the future IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... …you’ll take a deep dive into the science of healthy eating so that you can know how to leverage food for high energy and performance. Health and science journalist Max Lugavere studies and writes about ways that food and movement fuel you. And allow you some balance and freedom in your choices. He joins the show to round out a body of work that includes his best-selling “ Genius Foods ,” “ The Genius Life ” and now his latest to complete the trio: “ GENIUS KITCHEN: Over 100 Easy and Delicious Recipes to Make Your Brain Sharp, Body Strong, and Taste Buds Happy . “It's a kitchen and wellness guide,” Max explains. “I didn't want to just make a book of recipes. That would've been too easy. I wanted to make something that was going to stand the test of time and serve as a resource for people." His work was inspired by his mom’s diagnosis with a rare form of dementia in her 50s. He dedicated himself to her care and also began researching how to prevent cognitive decline through nutrition. “Though I began to cook when my mother could no longer cook herself, I realized that culinary literacy (like health literacy) had become yet another aspect of life that we had outsourced,” Max says in “Genius Kitchen.” I became passionate about creating healthy food that is delicious and easy to make." There’s a multi-billion dollar diet industry that makes nutrition confusing and complex. This conversation gets into the value of simple food, how to find your own food philosophy and why Max rejects diet dogma. So this is the episode for you to: -Learn science-backed tactics to improve digestion, increase nutrient extraction and stop common digestive complaints. -Get practical food lists and cooking methods for easy, nutritious meals that work for your performance goals and everyday life. -Find out how to eat like a “genius” with these topics: The upside & downside of plants Protein quality & muscle maintenance Organ meats Fantastic fats & ominous oils The shudder of sugar Essential fatty acids Calcium & the debate about dairy And more! More about Max: Max gets his curious on hosting The Genius Life podcast . He appears regularly on the Dr. Oz Show, the Rachael Ray Show, and The Doctors. He’s been featured on NBC Nightly News, The Today Show, and in The New York Times and People Magazine and contributed to Medscape, Vice, Fast Company, CNN, and the Daily Beast. He’s an international speaker who’s presented at events like South by Southwest, TEDx, the New York Academy of Sciences, and the Biohacker Summit in Stockholm, Sweden. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 25, 2022

Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month. Strategic eating fills micronutrient gaps. Use probiotics to turn down your allergies. Your DNA determines your coffee preferences. Got 3 seconds a day? Use it to strength train. Time your meals to control blood sugar and melatonin. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 24, 2022

NAD+ for Brain Health: https://innovativemedicine.com/DAVE and save 20% Support Immune & Digestive Health: https://justthrivehealth.com , use code ASPREY to get 15% off Apple Cider Vinegar Benefits: https://paleovalley.com/DAVE , use code DAVE to get 15% off your first order SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://farmersjuice.com/pages/upgrade . Use code UPGRADE and save $10 off any box of juice. IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... Did you know? Less than 9% of people meet a daily vegetable intake that’s best for their body. Soil has up to 50% less nutrition than 1945 And up to 40% of produce gets wasted on farms. Green juicing—done the right way—can upgrade all of those things. Junaid Kalmadi joins the show to talk about soil degradation, farming practices, and produce waste. He explains that it’s possible to do juicing safely and in ways that don’t break the planet even more. Junaid (with Dave as an advisor) founded Farmers Juice , a keto-friendly and functional green juice line that uses a cold-pressed process. “You separate the pulp from the juice, and you get this end product of this incredibly high nutrient-dense jolt of vitamins, enzymes, phytochemicals that give you this tangible positive effect within your biology, within your mood, within your own like mental state to perform your best,” Junaid says. It takes 1.5 pounds of produce (no kale!) to make one bottle of organic Farmers Juice. The juices also contain adaptogens, antioxidants, and mushrooms to boost focus, calm, and athletic performance. Along with finding out what’s in the juice, you’ll learn about nutrigenomics and how food information tells your body what to do. You’ll also learn how phytonutrients act as your genetic control system and keep you healthy. Food and nutrients directly, immediately, and specifically interact with our genes, controlling moment-to-moment changes in your physiology and biochemistry. For juicing 101, particularly ingredients and processing, take a listen to: Why Dave Asprey Changed His Mind About Juicing – #802 . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 22, 2022

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Biostack for High Performance: https://vatellia.com , use code DAVE2022 to save 10% or subscribe and save 15% + receive a free bottle of Kale Buster Hydrate with Electrolytes: https://DrinkLMNT.com/DAVE , get a free LMNT Sample Pack with 8 single-serving packets for the cost of shipping ($5 for U.S. customers) Fix Your Feet: https://www.vivobarefoot.com/us/daveasprey , use code ASPREY20 to get 20% off your first order and access to the VHealth Barefoot Movement online courses IN THIS EPISODE OF THE HUMAN UPGRADE ™ .. You’ll learn about the science-based benefits of intermittent fasting for women, especially during midlife. You’ll get details about intermittent fasting advantages for women like how to gain hormonal stability and metabolic health, and how to improve your energy. You’ll get practical intermittent fasting how-tos, nutritional guidelines, carb cycling recommendations, food lists, and recipes to try during your feeding window. Cynthia Thurlow joins the show to talk about how intermittent fasting can help women change their body, metabolic system and brain function. She has tips for women at all stages: from active menstrual cycles to perimenopause to menopause. Cynthia is a Johns Hopkins-trained nurse practitioner and functional nutritionist founded and serves as CEO of Everyday Wellness Project. She holds a Master of Science degree in Nursing and Functional Nutrition certifications with advanced trainings in Endocrinology and Gastroenterology. Her career in healthcare includes nearly 20 years of emergency medicine and cardiology experience. She brings a broad perspective when working with women to improve the state of their health. “I really start from a foundational level talking to women about fasting,” Cynthia says. “It's really honoring our own unique physiology. It's leaning into that menstrual cycle. It's leaning into the lifestyle piece that so much of us forget to talk about with our patients, our sleep quality, stress management, anti-inflammatory nutrition, our exercise quality, our connection with nature, all of which are critically important.” She also addresses diet dogma that frustratingly persists, even with established and emerging science about the benefits of intermittent fasting. She tackles this outdated dogma (and a lot more!) in her new book, “ Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging .” “[Intermittent fasting] restores our intrinsic rhythms, burns fat, regenerates our health right down to the cellular level, and stabilizes our hormones,” Cynthia says in her book. “In turn, we are less likely to develop obesity, diabetes, vascular diseases, and autoimmune disorders.” At the end of this conversation, you’ll have the tools to decide if intermittent fasting is the right choice for the state of your own health. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 19, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... … Dave talks with Michael Ford about low thyroid function, autoimmunity and aging concerns. At 70, Michael has been biohacking for over three years, takes a consistent supplement regimen, incorporates intermittent fasting, and does frequent microbiome and blood checks. He takes only one medication for low thyroid function and is looking for alternative ways to manage it. He suspects he has an autoimmunity issue and would like to explore that more. In the past few years, Michael has seen the health of colleagues, friends and elderly family members decline considerably. He’s concerned about aging and wants direction on how to live to be fully functional at 140 (or more!). With so much health information available to the general public – much of it contradictory, Michael asks Dave for insight and input. In this “Interventions With Dave” episode, Dave also talks with Michael about: Supplements Testosterone Cortisol-causing excess weight Visceral fat Healthy fats Red light benefits Dental health Breathing & mouth taping Improving brain blood flow They look at his health concerns through a new lens and discuss actionable next steps. Don’t miss the “ Links & Resources ” section below for specific information. Note: The "Interventions With Dave” recommendations are designed to help you upgrade yourself and your biology so you can perform better at everything you do. They are not, however, a substitute for advice or treatment by a trained medical professional that may be needed for specific health conditions, illness or injury. Listen to the Interventions With Dave series: Hacking Inflammation #915 Hacking Your Gut Microbiome #908 Hacking Menopausal Weight Gain #904 Hacking Eyesight #895 See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 17, 2022

Nature’s Nootropic: https://trukava.com , use code DAVE15 to get 15% off CARBON60 for Brain & Body: https://wizardsciences.com , use code DAVE for an exclusive discount on C60 products Trigger Autophagy: https://spermidinelife.us/dave , use code DAVE25 for 25% off your first month’s order Special offer for The Human Upgrade listeners: Go to https://www.viome.com/daveasprey , use code DAVE to get $20 off a Health Intelligence™ Test. IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... Dave’s good friend, entrepreneur and philanthropist Naveen Jain, joins the show to talk about the future of human biology and wellness. What’s new right now, what’s emerging, and what’s on the horizon. He’s been a guest several times before (see the Links & Resources section below!) and there’s always something new to learn when he and Dave get together. This time, they explore testing the human biome. Naveen’s a guy with enormous vision who builds companies and partners with others to tackle and solve the gnarliest problems affecting the health of our people and planet. He always encourages curiosity and big thinking: ““Curiosity is what drives the humanity forward. The day you stop being curious is the day you die.” In this discussion, you’re going to learn ways innovation can change human biology from a micro and macro level—from your cellular health to broader planetary issues. You’ll also learn how you can test to find out what’s happening within your gut, cells and immune system. With that knowledge and personalized recommendations, you’ll have the power to change your health for the better. Naveen founded, Viome, the worlds’ largest database of microbial gene expression. Its AI-driven personalized therapeutics platform and applications identifies predictive markers of chronic diseases. Viome does this by using a functional analysis of microbial, mitochondrial and human gene expression. “We actually see everything,” Naveen explains. “As long as an organism is alive, we see it. So whether it is a bacteria, virus, fungus, mold, it doesn't matter. We see everything.” In particular, Viome’s Health Intelligence™ Test looks at: gut microbiome mitochondrial function immune cell function cellular health stress response biological age The more data can inform what’s happening inside of you, the more resources you’ll have to improve your health. More about Naveen Jain: Naveen wrote the award-winning book, Moonshots: Creating a World of Abundance and created Mindvalley, Masterclass programs . He’s behind XPrize , a global future positive movement and is on the board of Singularity University . See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 15, 2022

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Business Growth With SEO: https://www.stephanspencer.com , get a FREE consultation Probiotic Eases Stress : https://www.omnibioticlife.com/DAVE/ , use code DAVE20 to get 20% off Control Blood Glucose: https://pendulumlife.com , sign up for membership to get monthly supply delivery, use code DAVE20 to save $20 on your first shipment IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... … Ellen Vora, M.D., takes a functional medicine approach to mental health that considers the whole person and addresses imbalance at the root. She’s a Yale and Columbia University educated holistic psychiatrist board-certified in psychiatry and integrative holistic medicine. She’s also an acupuncturist and yoga teacher. In her new book, “ The Anatomy of Anxiety: Understanding and Overcoming the Body's Fear Response ,” she takes on anxiety, which hits more than 40 million people in any given year. The pandemic drove that number up even more. Even if math isn’t your strong suit, you can understand these numbers: An estimated one out of every nine people, or 800 million people, suffer from a mental health disorder, the most common of which is anxiety. Up to 33.7 percent of Americans are affected by an anxiety disorder in their lifetime. Conventional medicine tends to view anxiety as a “neck up” problem of brain chemistry and psychology. Dr. Vora disagrees. She suggests that various physiologic inputs influence anxiety symptoms. “What we've been indoctrinated with is this idea that our mental health is genetically determined chemical imbalance,” Dr. Vora says. “There's some validity to that, although I think, for the most part, any chemical imbalance is often a downstream effect of a state of imbalance happening elsewhere in the physical body.” In this episode, you’ll learn: the difference between avoidable, purposeful, false and true anxiety; simple strategies for tuning into “true” anxiety and using its benefits; how your body may be physiologically out of balance (immunity, gut health, inflammation); how “hanxiety” means that blood sugar is affecting your anxiety; actionable lifestyle factors to bring yourself back into balance; how to manage medication withdrawl; and how to reframe your understanding of, and relationship with, anxiety. Dr. Vora also confronts what she calls techxiety. This can include a boundaryless workplace, how the posture of screen use signals your body for anxiety, and, of course, social media. Research shows social media is associated with higher rates of anxiety and depression. Just 20 minutes of Facebook can impact mood. So much of how you live your life as an adult profoundly impacts how your mental health manifests, and that's the part you can control. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 11, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... … Dave talks with Cindy Fraley-Hunter about system-level inflammation and her fear of having an early heart attack like her father because they have such similar genes. Cindy thought she was healthy until after the birth of her daughter at 42. She was constantly tired. Her physician told her that was just to be expected because she was a geriatric pregnancy. That unhelpful advice ignored her body functioning and lacked actionable solutions. She then survived a case of MRSA and received Hashimoto’s and rheumatoid arthritis diagnosis. She continued to have high cholesterol and a high CAD calcium heart score. She’s scared her life will be cut short. Feeling like conventional medicine is failing her, Cindy has turned to supplements instead of prescription drugs. She says she’s “embracing biohacking to save my life.” In this “Interventions With Dave” episode, Dave walks Cindy through her most recent labs and other test results. They look at her health concerns through a new lens and discuss actionable next steps. Don’t miss the “Links & Resources” section of episode web page #915 for specific information. Note: The "Interventions With Dave” recommendations are designed to help you upgrade yourself and your biology so you can perform better at everything you do. They are not, however, a substitute for advice or treatment by a trained medical professional that may be needed for specific health conditions, illness or injury. Listen to the Interventions With Dave series: Hacking Your Gut Microbiome #908 Hacking Menopausal Weight Gain #904 Hacking Eyesight #895 Coffee & Bohacking with Dave Asprey (coffee + minerals) - toxins = power: Discover the energy and high performance that come from Danger Coffee, designed with your biology in mind. https://dangercoffee.com 8th Annual Biohacking Conference: Come join like-minded people September 15, 16 & 17 in Beverly Hills, Calif., for three days of awesome! You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. https://biohackingconference.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 10, 2022

Natural First-Aid Healing: https:// 3rdrockessentials.com , use code DAVE to save 20% Non-Tobacco Nicotine Alternative: https://lucy.co , use code DAVE20 to get 20% off your first order of pouches, gums, or lozenges Biostack for High Performance: https://vatellia.com , use code DAVE2022 to save 10% or subscribe and save 15% + receive a free bottle of Kale Buster IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... … you’ll get a look at synthetic biology (SYNBIO) through the lens of quantitative futurist Amy Webb in Part 2 of a special two-part episode. The Part 1 episode #913 explores the scientific perspective with microbiologist and geneticist Andrew Hessel. Amy and Andrew recently authored, “ The Genesis Machine: Our Quest to Rewrite Life in the Age of Synthetic Biology .” SYNBIO is the promising and controversial technology platform that combines biology and artificial intelligence. Amy investigates what SYNBIO means for people, commerce and the planet. “This is a book about science,” Amy describes, “but I did not want to write a science book. This is also a business book. It's an understanding-your-own-body book.” She’s a futurist who works with data and does predictive modeling. Her academic background includes game theory and economics Amy founded the Future Today Institute to help companies understand the forces that will shape their futures. She’s a professor of strategic foresight at the NYU Stern School of Business and a Visiting Fellow at Oxford University’s Säid School of Business. She writes extensively about biotechnology, artificial intelligence, technology policy, and business strategy. “This emerging field of science—synthetic biology—promises to reveal how life is created and how it can be recreated, for many varied purposes, as explained in “The Genesis Machine:” to help us heal without prescription medications, to grow meat without harvesting animals, and to engineer our families when nature fails us. With SYNBO developments come a slew of considerations about how to manage it responsibly. “For the most part, in the US, the regulation is on the end product,” Amy says. “Nobody wants to regulate the process, because we don't want to hamper innovation. However, it does start to raise some gnarly questions when we're talking about alternative uses or different uses for some of these technologies, or cross-border use.” “There's some alignment globally on what's called germline editing, which is when you edit the genome to make it heritable. So whatever that is passes on. At the moment, just about 190 countries have aligned [to agree] that they don't want that to happen. But outside of that, there's a lot of confusion.” See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 9, 2022

Nature’s Nootropic: https://trukava.com ,use code DAVE15 to get 15% off Apple Cider Vinegar Benefits: https://paleovalley.com/DAVE , use code DAVE to get 15% off your first order Franchise Opportunity: https://ownanupgradelabs.com , to check out the fitness center of the future IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... … you’ll learn about the implications of synthetic biology in Part 1 of a special two-part episode. Andrew Hessel and Amy Webb recently authored, “ The Genesis Machine: Our Quest to Rewrite Life in the Age of Synthetic Biology .” This Part 1 episode gets into the scientific perspective with Andrew. Part 2 on episode #914 explores the futurist perspective with Amy. Ask yourself, if you could edit your genes—to fix infertility, diabetes or even depression—would you do it? That’s the premise, and the promise, of synthetic biology. And a reality you’ll have to wrestle with. To make these decisions intelligently requires a deeper—and urgent—understanding of what’s happening in science. Right now, scientists are rewriting the rules of our reality. They can use computers to gain access to the cells of any living organism and write new, potentially better, biological code. Andrew—a microbiologist and geneticist—works on the leading edge of genomics and bioinformatics. He’s been immersed in the world of synthetic biology for years and joins the show to explain new advancements. As a scientist, communicator, and investor, he explores the future of biology and biotechnology. He co-founded the Center of Excellence for Engineering Biology and the Genome Project-write . The Genome Project-write is an international scientific effort that designs and builds large genomes, including the human genome. As we embrace that life no longer will be a game of chance, it will be the result of design, selection and choice, more choices have to be made. Decisions like who gets to program life, create new life forms, and even bring former life back from extinction? “The Genesis Machine" is a book about science, but it's not written for scientists, Andrew says. “It's about some amazing people and stories and we've got some fun scenarios that help you think about where some of this stuff is going. But really, this is a technology that we're all building day by day.” See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 4, 2022

Control Blood Glucose: https://pendulumlife.com , sign up for membership to get monthly supply delivery, use code DAVE20 to save $20 on your first shipment Kickstart Autophagy: https://timelinenutrition.com/DAVE , use the code ASPREY10 to get 10% off any plan NAD+ for Brain Health: https://innovativemedicine.com/DAVE and save 20% SPECIAL OFFERS FOR THE HUMAN UPGRADE LISTENERS: Pre-order your copy of “ Unlocking the Keto Code ” before March 7, 2022, and receive your choice of “The Energy Paradox,” or “The Plant Paradox,” or an early release chapter of “Unlocking the Keto Code,” and an exclusive sneak peek digital recipe guide! Go to https://drgundry.com for details. Get 30% off products at https://gundrymd.com . Use code DAVE30 at checkout. IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... … Steven Gundry, M.D., introduces you to the biological mechanism that makes keto diets so successful: a cellular process known as “mitochondrial uncoupling.” He’s spent the last two decades studying the microbiome and uses diet and nutrition as a key form of treatment for people who want to improve their body health and performance. You may already know Dr. Gundry from his bestselling books like: “The Plant Paradox,” (lectins!) “The Longevity Paradox” and “The Energy Paradox.” This discussion gets right into new science that’s overhauling what you think you know about a keto diet. In his newest book, “ Unlocking the Keto Code: The Revolutionary New Science of Keto That Offers More Benefits Without Deprivation ,” Dr. Gundry debunks common myths about keto and explains: How ketosis actually works, What’s going on with ketones, and What your mitochondria has to do with all of this. You don’t have to restrict all carbs to reap the benefits of ketosis; you simply have to “unlock” mitochondrial uncoupling, Dr. Gundry explains. He shares eight “keys” that unlock the keto code. You’ll get real food examples of how to ignite this process without the monotonous, limiting, high-fat diet. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Mar 1, 2022

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Mattress Temperature Tech: https://www.eightsleep.com/dave , use code DAVE to save $250 on the Pod Pro Must-Have Magnesium: https://magbreakthrough.com/DAVE , use code DAVE10 to get a 10 percent discount Organically & Biodynamically Grown: https://www.dryfarmwines.com/dave , get an extra bottle in your first box for just a penny. (Free shipping except Hawaii & Alaska.) IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... Entrepreneur, investor and artist Payal Kadakia brings a fresh perspective to your understanding of goals. She knows a lot about setting big goals and reaching them. She founded ClassPass and over a decade grew it to become the leading fitness and wellness membership service valued at over $1 billion. Mindbody acquired ClassPass in October 2021. At that time, members had logged more than 100 million hours of workouts across 30,000 partner studios in over 30 countries. We’re going to talk today about how you can upgrade your own goal setting with “ LIFEPASS: Drop Your Limits, Rise to Your Potential .” Using her company Class Pass as an example, Payal highlights the importance of knowing your strengths, your unique talents, who you are, and investing in the right people and mentors to show you the way. Payal gives insight on how to set boundaries in service to your priorities, and how every minute of the day belongs to YOU, not anyone else. This means you don’t have to hold onto any guilt about doing what's right for you. You’re more likely to reach your goals when you get to let go of the pressure to achieve a traditional kind of success and instead fuel your life with purpose. And when you focus on a life of creativity, you get to live the life you most want to live. The 4-step LifePass Method combines intuition, pie-in-the-sky dreams, micro focus, and macro goals. Reflect : Where have you been? Dream : Where do you want to go? Focus : What are your priorities? Set Goals : What’s the plan? Payal, an Operations Research and Economics graduate from MIT, been featured in most major news outlets; listed as Fast Company ’s 100 Most Creative People; and named to Fortune 's 40 under 40 list. She formerly worked as a consultant at global management consulting firm Bain & Company and was part of Warner Music Group’s Digital Strategy and Business Development Group. She’s also got an extraordinary artistic side. She founded The Sa Dance Company in 2008 and serves as Artistic Director. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Feb 25, 2022

Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month. Breathing coordinates neuronal activity—even without smell Mindful breathing in virtual reality can control real pain Circadian cycle affects immune cells and Alzheimer’s plaques Brain refresh lags when processing visual stimuli Medical repression in the days of Ivan the Terrible See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Feb 25, 2022

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Hydrate with Electrolytes: https://DrinkLMNT.com/DAVE , get a free LMNT Sample Pack with 8 single-serving packets for the cost of shipping ($5 for U.S. customers) Strengthen Your Back, Align Your Spine: https://bodyaline.com , use code DAVE100 to save $100 Fix Your Feet: https://www.vivobarefoot.com/us/daveasprey , use code ASPREY20 to get 20% off your first order and access to the VHealth Barefoot Movement online courses IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... “Americans are the unhappiest they have been since the Great Depression,” says Dr. Daniel Amen. But he’s determined to change that. He’s a physician and double board-certified psychiatrist who looks at happiness as a brain function. After studying more than 200,000 brain scans of people from 155 countries, Dr. Daniel Amen discovered five primary brain types and seven neuroscience secrets that influence happiness. “I wanted to spend my time and energy and research on happiness because, ultimately... happiness is a moral obligation because of how you impact other people,” Dr. Amen says. “The big central point [is] the brain is the organ of happiness, and if your brain is not healthy, you are not likely to be happy.” What makes you happy? The answer lies in knowing your specific brain type and how it’s being influenced by seven specific chemicals. Happiness originates in distinct brain regions: pleasure in the orbitofrontal cortex; motivation and habit formation in the basal ganglia; and mood and cognitive flexibility in the brain stem. You may be one or a combination of these five primary brain types: ( take this brain assessment to find out yours ) Balanced : you have a very healthy brain Spontaneous : you have low dopamine Persistent : you’re often worried, rigid, and inflexible Sensitive: you need other people and isolation is hard Cautious: your GABA levels are low Learn more about brain types and what actually boosts your happiness according to neuroscience in Dr. Amen’s book, " You, Happier: The 7 Neuroscience Secrets of Feeling Good Based on Your Brain Type .” “Happiness comes from moving your life forward toward your life goals with meaning and purpose, based on your values, despite whatever obstacles are in your way,” Dr. Amen says. “A happy life doesn’t focus on the past with regret or look to the future with fear.” See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Feb 22, 2022

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Non-Tobacco Nicotine Alternative: https://lucy.co , use code DAVE20 to get 20% off your first order of pouches, gums, or lozenges Tasty Keto Bread & Chips: https://www.uprisingfood.com/DAVE , use code DAVE to get $10 off the starter bundle Apple Cider Vinegar Benefits: https://paleovalley.com/DAVE , use code DAVE to get 15% off your first order SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Call the phone number listed on the Docere Clinics website : (435) 604-0438. Mention you heard about stem cell treatments on the Dave Asprey podcast and get half off a consultation. IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... …you’re going to find out about Dave’s recent stem cell procedure and the newest technology stem cell medicine happening at Docere Clinics in Park City, Utah. Dr. Harry Adelson was one of the earliest adopters of the use of stem cells for the treatment of chronic musculoskeletal pain. His practice has offered 100% Regenerative Injection Therapy since 2002 and 100% stem cell therapy since 2010. He’s performed more than 6,000 stem cell procedures and invented the Full Body Stem Cell Makeover®, the most comprehensive stem cell upgrade currently available. His colleague, Dr. Amy B. Killen performs anti-aging and regenerative medical treatments. She’s fellowship trained in Anti-Aging and Regenerative Medicine through the American Academy of Anti-Aging Medicine. She’s also done extensive additional training in aesthetics, platelet rich plasma and stem cells, hair restoration, bio-identical hormones, nutrition, fitness and sexual health. Drs. Adelson and Killen performed Dave’s original Full Body Stem Cell Makeover®, which used Dave's own stem cells from his fat and bone marrow, as well as extracellular vesicles. This episode gets into new developments in stem cell treatments, like the advent of VSEL (very small embryonic-like stem cells) technology. Stem cells therapy may be right for you if you’re interested in: Better skin Increased sexual performance Decreased pain Improved functional body movement Preventive aging treatment See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .

Feb 19, 2022

IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... … Dave talks with Tim Waters about ways to improve the health of his gut microbiome. A former wrestler, Tim spent years cutting weight. He experienced gall stones and eventually had his gall bladder removed 20 years ago. That led to long-term use of proton pump inhibitor pharmaceutical. Now over 50, Tim wants to wean off the pharmaceutical and heal his gut. He’s made some progress on his own but has some complicating factors at play. Here are a few things you'll learn in this “Interventions with Dave” episode: What causes low stomach acid The difference between a proton pump inhibitor and an H2 blocker How certain foods influence gastric reflux How to manipulate your gut pH (acid and heat) The role enzymes play in digestion The importance of bile The benefits of butyric acid How to get your good gut bacteria working How to check your methylation Why tracking your blood pressure regularly is a great idea This conversation covers a lot of gut ground! Don’t miss Dave’s intervention recommendations in the “Links & Resources” section of the episode webpage: https://daveasprey.com/intervention-tim-waters-908/ Note: The "Interventions With Dave” recommendations are designed to help you upgrade yourself and your biology so you can perform better at everything you do. They are not, however, a substitute for advice or treatment by a trained medical professional that may be needed for specific health conditions, illness or injury. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .