Research in Action

Where are the biggest opportunities to leverage AI in cancer diagnosis and treatment? What are the biggest barriers remaining to move away from a one-treatment-fits-all approach to treating cancer? And how are AI, radiomics, machine learning and deep learning helping to understand which patients will respond best to which treatments?   We will learn all that and more in this episode of Research in Action with Otavio Clark, M.D. Ph.D. and Principal Research Consultant at Oracle Life Sciences.   ---------------------------------------------------------   Episode Transcript:   00;00;00;00 - 00;00;26;16 Where are the biggest opportunities to leverage AI in cancer diagnosis and treatment? What are the biggest barriers remaining to move away from a one treatment fits all approach to treating cancer? And how are ready omics, machine learning and deep learning. Figuring out which patients will respond best to which treatments will learn. All that and more on research and action in the lead in the world.   00;00;26;19 - 00;00;48;02 Hello and welcome to Research and Action, brought to you by Oracle Lifesci Answers. I'm Mike Stiles, and today our guest is Ottavio Clark and Oncology and Specialty Therapeutics executive at Oracle Life Sciences. Now that's a field he's been in his entire career. He has his Ph.D. in oncology and specializes in all things evidence based research, real world data, real world evidence.   00;00;48;02 - 00;01;13;25 And what we're going to be talking about today, AI and the critical field of cancer research. Octavio, thanks a lot for being with us today. I might tinker for the end of the invite. It's a pleasure to be here. And we are really discussing a fascinating issue. That is how the ACA is changing the healthcare landscape. But before we start, I'd like to make a disclaimer.   00;01;13;28 - 00;01;45;27 We would discuss a lot about the study's findings, but we have to to have in our minds that these results that you discuss, they are still early. These findings. We have yet to be validated in prospective longer term studies, but we will discuss the only things that we have a clear direction of the trend. You added that things are going, so it's important for everybody to to think about this product by the cancer, something introductory.   00;01;45;29 - 00;02;10;17 So I think that's pointing towards trends but not about something definitive when you see something moving on in this direction. Okay. Okay. Yeah, that's totally understood and understandable that that would be the case. I do really want to dive right into this so we can make good use of our time. So what are some of the more impressive advancements that we've made in cancer treatment lately?   00;02;10;17 - 00;02;40;18 And does that mean success rates are satisfactory? Has personalized medicine helped to that? Where are those most promising opportunities to improve personalized medicine where cancer is concerned? It's a revolution in personalized medicine. It changes e

What is the MOSAIC-NLP project around structured and unstructured EHR data? Why is structured data not really enough for drug safety studies? And to what degree is NLP speeding up access to data and research results? We will learn all that and more in this episode of Research in Action with Dr. Darren Toh, Professor at Harvard Medical School and Principal Investigator at Sentinel Operations Center. www.oracle.com/health www.oracle.com/life  www.sentinelinitiative.org -------------------------------------------------------- Episode Transcript: 00;00;00;00 - 00;00;26;14 What is the MOSAIC and LP project around structured and unstructured data? Why is structured data not really enough for drug safety studies? And to what degree is NLP speeding up access to data and research results? We'll find all that out and more on this episode of Research in Action. Hello and welcome to Research in Action, brought to you by Oracle Life Sciences.   00;00;26;14 - 00;00;50;14 I'm Mike Stiles. And today our guest is Dr. Darren Toh, professor at Harvard Medical School and principal investigator at Sentinel Operations Center. He's got a lot of expertise in Pharmacoepidemiology as well as comparative effectiveness research and real-world data. So, Darren, really glad to have you with us today. Thank you. My pleasure to be here. Well, tell us how you wound up where you are today.   00;00;50;14 - 00;01;26;22 What what attracted you in the beginning to public health? Good question. So I trained in pharmacy originally, and I got my Masters degree in Pharmaceutical Outcomes Research at a University of Chicago, Illinois, Chicago. And it's where I first learned about a field called Pharmacoepidemiology, which sort of very interesting to me because I like to solve problems with methods and data and pharmacoepidemiology.   00;01;26;22 - 00;02;00;29 It seems to be able to teach me how to do that. So I got into the program at the Harvard School of Public Health, and when I was finishing up, I was deciding between staying in academia and going somewhere and getting a real job. And that's when I found out about an opportunity within my current organization and I've heard great things about this organization.   00;02;00;29 - 00;02;29;26 So I thought I would give it a try. And the timing turned out to be perfect because when I joined, our group was responding to a request for proposal for what is called a mini sentinel pilot, which ultimately became the sentinel system that we have today. So I've been involved in the Sentinel system since the very beginning or before we began.   00;02;29;28 - 00;03;02;25 And for the past 15 years I've been with the system and the program and because I really like its public health mission and I'm also very drawn to the dedication of FDA, our partners and my colleagues to

How do clinical research funders operate? Why do patient-centered outcomes matter so much and improve the quality of research? And how is patient-led research being applied to clinical care? We will learn all that and more in this episode of Research in Action with Greg Martin, Chief Officer for Engagement, Dissemination, and Implementation at the Patient-Centered Outcomes Research Institute (PCORI).   www.oracle.com/health www.oracle.com/life  www.pcori.org/   --------------------------------------------------------   Episode Transcript:   00;00;00;00 - 00;00;21;14 How do clinical research funders operate? Why do patient centered outcomes matter so much and improve the quality of research? And how is patient led research being applied to clinical care? We'll find all that out and more on this episode of Research in Action.   00;00;21;16 - 00;00;45;16 Hello and welcome to Research in Action, brought to you by Oracle Life Sciences. I'm Mike Stiles and today our guest is Greg Martin, chief officer for engagement, dissemination and implementation at the Patient Centered Outcomes Research Institute, referred to as PCORI. Greg's been with the organization 12 years or so, and prior to that spent time as manager of State government affairs for the American Academy of Family Physicians.   00;00;45;19 - 00;01;05;09 And we're going to be talking about no big surprise here, patient centered outcomes. So, Greg, we really appreciate you being with us. Well, thank you, Mike. It's a real pleasure and an honor to be here with you. I've listened to some of the podcasts and greatly benefited from the insights and the advice that you're bringing to folks through this, through this series.   00;01;05;09 - 00;01;23;29 So really just a real pleasure to be a part of it. Yeah, the show is really picking up steam and audience and getting some legs under it. All right. I guess let's start off by just having you describe your specific role at PCORI. What's your primary goal every day? And kind of also tell us about the overall purpose of PCORI.   00;01;24;02 - 00;01;46;12 Yeah, that's a great question. You know, and I always kind of joke around with folks that, you know, my mom does the classic two Bobs question from office space here. Remember that movie when I asked you about my job? What what exactly, son, would you say it is that a chief officer for engagement, dissemination and implementation does and it's a limited it's an uncommon title.   00;01;46;12 - 00;02;15;27 But the way I simplify it is that, you know, I get to work with a great team that is focused every day on how it is that people can be involved in the work that PCORI does as a funder, how they can be involved in the work that PCORI has funded and also how they can use in their everyday lives the evidence that property is funded and that last bit they're around evidence that that's

What makes multidisciplinary collaboration the key to health and life sciences research and innovation? What is the impact of bundled, integrated solutions on the patient experience? And how can we invest in what matters most in research while streamlining the entire process? We will learn all that and more in this episode of Research in Action with Frank Baitman, Digital Health, Data, and Technology Executive; and former Chief Information Officer of the US Department of Health and Human Services.   http://www.oracle.com/health http://www.oracle.com/life   -------------------------------------------------------   Episode Transcript:   00;00;00;02 - 00;00;27;22 What makes multidisciplinary collaboration the key to health care innovation? What is the effect of bundled, integrated solutions on the patient experience and how can we invest in what matters most while streamlining the entire process? We'll find all that out and more on Research in Action. Hello and welcome to Research in Action, brought to you by Oracle Life Sciences.   00;00;27;22 - 00;00;52;08 I'm Mike Stiles. And today our very special guest is Frank Bateman, a digital health data and technology executive. He's currently a senior health IT advisor and was a former chief information officer of the U.S. Department of Health and Human Services. Oracle Life Sciences has an e-book on the next phase of growth for the Life Sciences industry, and Frank was a really valuable resource for that.   00;00;52;08 - 00;01;22;00 He's got a lot of great thoughts on how pharma and biotech are investing in tech to support things like personalized medicine, improved clinical trials and drug safety tracking. That's why we wanted to get him on the podcast. So Frank, thanks so much for joining us. Thanks. It's great to be here, Mike. We appreciate it. Well, we got a lot of ground to cover, but I know you went into corporate strategy in the beginning of your career and through the bulk of your career, but obviously somewhere down the line you started crossing paths with government.   00;01;22;00 - 00;01;42;04 So what did that involve? How did that happen? Well, I've been lucky enough to pursue my interests wherever they took me. I hadn't expected to pursue a career in the life sciences and health care when I started out focused on nuclear arms control. But my interest in technology actually came about from my work on verification measures for a nuclear test ban.   00;01;42;21 - 00;02;09;05 Technology first took me to IBM Research and then under IBM corporate strategy, as you mentioned, when in in corporate, I oversaw the company's ten year outlook. And as a tech company, we saw high performance computing in the life sciences staring us in the face. We needed to be in it. And our chairman at the time, Lou Gerstner, accepted a recommendation that we invest 100 million to launch a business unit f

Why is the confluence of healthcare and life sciences happening? What are the two biggest mistakes of technology in healthcare? And how can research insights be embedded into every care decision? We will find out all that and more with our guest Dr. David Feinberg, a medical professional and healthcare industry executive and current Chairman of Oracle Health.   http://www.oracle.com/health http://www.oracle.com/life    --------------------------------------------------------   Episode Transcript:   00;00;00;02 - 00;00;27;22 What makes multidisciplinary collaboration the key to health care innovation? What is the effect of bundled, integrated solutions on the patient experience and how can we invest in what matters most while streamlining the entire process? We'll find all that out and more on this episode of Research in Action. Hello and welcome to Research in Action, brought to you by Oracle Life Sciences.   00;00;27;22 - 00;00;52;08 I'm Mike Stiles. And today our very special guest is Frank Bateman, a digital health data and technology executive. He's currently a senior advisor to Oakland's De Silva and Phillips and was a former chief information officer of the U.S. Department of Health and Human Services. Oracle Life Sciences has an e-book coming on the next phase of growth for the Life Sciences industry, and Frank was a really valuable resource for that.   00;00;52;08 - 00;01;22;00 He's got a lot of great thoughts on how pharma and biotech are investing in tech to support things like personalized medicine, improved clinical trials and drug safety tracking. That's why we wanted to get him on the podcast. So Frank, thanks so much for joining us. Thanks. It's great to be here, Mike. We appreciate it. Well, we got a lot of ground to cover, but I know you went into corporate strategy in the beginning of your career and through the bulk of your career, but obviously somewhere down the line you started crossing paths with government.   00;01;22;00 - 00;01;42;04 So what did that involve? How did that happen? Well, I've been lucky enough to pursue my interests wherever they took me. I hadn't expected to pursue a career in the life sciences and health care when I started out focused on nuclear arms control. But my interest in technology actually came about from my work on verification measures for a nuclear test ban.   00;01;42;21 - 00;02;09;05 Technology first took me to IBM Research and then under IBM corporate strategy, as you mentioned, when in in corporate, I oversaw the company's ten year outlook. And as a tech company, we saw high performance computing in the life sciences staring us in the face. We needed to be in it. And our chairman at the time, Lou Gerstner, accepted a recommendation that we invest 100 million to launch a business unit focused on the life sciences.   00;02;09;19 - 00;02;36;24 So I love the idea. You were actually serving in the Obama admini

How can shifting mindsets fuel the next wave of innovation in the pharmaceutical and life sciences industry? In what ways can we ensure the vast amounts of health data are utilized securely and effectively to foster groundbreaking medical advancements? And how is Oracle's new Health Data Intelligence poised to transform the industry in an unprecedented manner? You'll learn all that and more with our guest Michael Fronstin, Vice President and Chief Commercial Officer at Oracle Life Sciences, who has worked across nearly every area of the industry from positions at Merck to J 00;00;04 - 00;00;26;25 In what ways do the mindsets in the pharma industry need to change? How can we make sure massive amounts of health data is applied to practical effect? And how might Oracle's new Health Data Intelligence platform be an unprecedented game changer? We'll find all that out and more on Research in Action. Hello, welcome to Research in Action, brought to you by Oracle Life Sciences.   00;00;26;25 - 00;00;49;15 I'm Mike Stiles. And today we've got a guest who's been a veteran in the life sciences industry and who knows Oracle Life Sciences quite intimately because the guest is Michael Fronstin, vice president and chief commercial officer at Oracle Life Sciences. He's worked across nearly every area of life sciences, from positions at Merck to J 00;49;15 - 00;01;11;25 So, Michael, thanks for being here. Thanks, Mike. Happy to be here and thank you so much for hosting this session. Really appreciate it. Great. Well, you know, you're the perfect person to talk to about what I want to talk about, which is changing people's minds and changing how we even approach and think about life sciences. So you've got that to look forward to.   00;01;11;25 - 00;01;34;28 But first, let's learn a little bit more about you. How did your interests and opportunities in life take you down the path that led you to where you are now? Yeah, thanks for that question. That's that's a great question to start out with. I'll tell you that as human beings, we all have something going on in terms of health care, whether it's impacting ourselves or friends or family, everyone's going through something.   00;01;34;28 - 00;01;56;25 At some point. You just don't know what the magnitude is or how long lasting, right? So having patience and empathy is so important. And of course myself, I've gone through things and unfortunately starting at a very early age of 12, I lost my best friend to the brain cancer and from the time I was 12 to the time I was 21, unfortunately, I lost a lot of people to different health ailments.   00;01;57;11 - 00;02;17;10 I guess, climaxing with losing my father when I was 21 years old. During that time, I always thought about health care and how it was impacting the people around me and wondering what could

What are the best ways to set up public, private, and academic clinical research partnerships? How do we get these public-private partnerships (PPP) to work most effectively? And who should be in charge of what in multistakeholder research collaborations? We will get those answers in more in this episode of Research in Action with our guests Rob King, President and CEO of FHI Clinical; and Dr. Kristen Lewis, Head of Clinical Operations at the Center for Vaccine Innovation and Access at PATH.   ---------------------------------------------------------   Episode Transcript:   00;00;00;01 - 00;00;22;22 What are the best ways to set up public-private clinical research projects? Where does and should the money for such research come from and who should be in charge of what? We'll get those answers and more on this episode of Research in Action. Hello and welcome to Research in Action, brought to you by Oracle Life Sciences.   00;00;22;22 - 00;00;50;05 I'm Mike Stiles. And today we're just trying to outdo ourselves by talking to not one, but two very interesting people. First is Rob King, president and CEO of FHI Clinical. FHI uses Oracle's clinical trial software for their clinical operations and partner with public entities like PATH, which brings me to Dr. Kristen Lewis, who is Head of Clinical Operations at the Center for Vaccine Innovation and Access at PATH.   00;00;50;26 - 00;01;29;23 I could go through what each of these organizations do just to hear myself talk, But why do that when I have both of you here? So, Rob, tell us what FHI Clinical does. Yeah, I think Mike, so clinical in a contract, they were actually for profit and hearing of a large nonprofit called F8 had three ethically and while we are for profit empathy, our mission is to address unmet research needs and maximum social impact pouring into development of medical treatment around the world.   00;01;30;04 - 00;01;58;20 While we work globally, we tend to focus on the low and middle income country on the whole pharma and biotech client are also include nonprofits and government. Empathy. Well with biotech receive public funding and path having him be one of our client. Appreciate Kristen being here arguing that four years ago and I'm currently the CEO and I'm happy to be here.   00;01;58;20 - 00;02;22;19 Well great. Kristen what about PATH? Yeah, thanks for the introduction, Mike. It's a pleasure to speak with you and Rob today and have the opportunity to contribute to this discussion. So most people listening to this podcast may not be familiar with PATH. We're a nonprofit global public health organization with approximately 1600 employees worldwide. Our headquarters are in Seattle, Washington, and we have offices across the African and Asian continents and Europe.   00;02;22;19 - 00;02;53;00 Some of the locations we have offices in include Kenya, Ethiopia, Senegal, Uganda, Zambia, India, Vietnam, Ukraine. And I could go on, but I'll I'll hold hold it there. Our mission is to adva

How can patients and their families become more integral in the clinical research process? How can patient-led research become more accepted in the scientific community? How are inspiring groups forging new, collaborative paths for science and medicine, and reshaping how medical research is conducted?  We will tackle those questions and much more in this episode with Amy Dockser Marcus, a Pulitzer Prize-winning journalist and author of the recently published book, "We the Scientists: How a daring team of parents and doctors forged a new path for medicine." Amy is a veteran reporter at the Wall Street Journal and won her Pulitzer Prize for Beat Reporting in 2005 for her series of stories about cancer survivors and the social, economic, and health challenges they faced living with the disease. She has covered science and health at the Journal for years, and she also earned a Masters of Bioethics from Harvard Medical School.  -------------------------------------------------------- Episode Transcript: 00;00;00;00 - 00;00;24;19  How can patients and their families become the centers of research? What is open science and who are citizen scientists? We'll explore those questions and more on this episode of Research and Action in the lead in. Hello and welcome back to Research and Action, brought to you by Oracle Life Sciences. I'm your host, Mike Stiles, and our guest is Amy.     00;00;24;19 - 00;00;48;22  Dr. Marcus That's right, that Amy Marcus, the Pulitzer Prize winning journalist, reporter at the Wall Street Journal, a Pulitzer Prize, was won for her series of stories in 2005 about cancer survivors and the social and financial challenges of living with cancer. Her beat, as you would imagine, has long been science and health. And she holds a master's of bioethics from Harvard Medical School, and she's an author.     00;00;48;22 - 00;01;04;26  Her book is We The Scientists How a Daring Team of Parents and Doctors Forged a New Path for Medicine. So this should be interesting as we talk about collaborative, open science and the rise of citizen scientists and patient led research. So thanks for being with us, Amy.     00;01;05;01 - 00;01;06;22  I'm happy to speak with you today.     00;01;06;22 - 00;01;26;29  Great to have you. In your new book, you take readers through some really, frankly, heart wrenching experiences that patients and their fa

How can an extensive collection of real-world data help find more diverse and better participants for clinical trials? How do we create a continuously learning ecosystem that helps bridge the gap between clinical research and clinical care? And what are the biggest challenges to patient record standardization and personalized healthcare? We will learn that and more in this episode with Dr. Lu de Souza, Vice President and Executive Medical Officer of the Learning Health Network, which is a division of Oracle. Dr. de Souza leads a team that seeks to help health organizations integrate clinical research into everyday care. That means addressing clinical discovery cost, time, and patient inequities. She's also a huge advocate for real-world data and bringing technology to bear for true healthcare advancements. Dr. de Souza has years of experience in health informatics and was the most recent CMO of Cerner in North America. She practiced pediatric hospital and emergency medicine until 2020 and has held multiple leadership and teaching positions.  -------------------------------------------------------- Episode Transcript: 00;00;00;01 - 00;00;25;21  How can an extensive collection of real-world data help find diverse participants for clinical trials? Are some organizations already using the concepts of a continuously learning ecosystem. And what are the biggest remaining challenges to patient record standardization and personalized health care? We'll find all that out and more on today's Research in Action episode.     00;00;27;05 - 00;00;47;23  Hello and welcome to Research in Action, brought to you by Oracle Life Sciences. I'm Mike Stiles and our guest today is Dr. Lu de Souza, vice president and executive medical officer of the Learning Health Network, which is a division of Oracle Life Sciences. In a nutshell, Dr. de Souza leads a team that seeks to help health organizations integrate clinical research into everyday care.     00;00;48;03 - 00;01;11;28  That means addressing clinical discovery, cost time and patient inequities. She's also a huge advocate for real-world data, bringing technology to bear for true healthcare advancements. Dr. de Souza has years of experience in health informatics and was the most recent CMO of Cerner in North America. She practiced pediatric hospital and emergency medicine until 2020 and has held multiple leadership and teaching positions.     00;01;12;12 - 00;01;16;03  Dr. de 'Souza, thank you so much for taking the time to be our guest

Research reveals that 95% of patients do not participate in clinical trials. How do we find better ways to connect willing and qualified participants to clinical trials? How do we ensure diversity in participant populations? And how can we make access to clinical trials more patient-friendly? We will get those answers and more in this episode with Brandon Li, Co-Founder at Power. Power is a fast-growing startup building a patient-friendly way to get access to clinical trials and is working to increase the diversity in clinical trials. -------------------------------------------------------- Episode Transcript: 00;00;00;03 - 00;00;17;02  Are there better ways to connect willing and qualified participants to clinical trials? How do you ensure diversity in participant populations? And why do 97% of patients not participate in clinical trials? We'll get those answers and more on this episode of Research in Action.     00;00;18;07 - 00;00;19;19  The need to.     00;00;21;14 - 00;00;41;18  Build the Hello and welcome to Research and Action, brought to you by Oracle Life Sciences. I'm Mike Stiles, and our guest today is Brandon Lee, co-founder at Power. Power is building a patient friendly way to get access to clinical trials, and they're working on increasing the diversity in clinical trials. Brandon, thanks for taking the time to be with us today.     00;00;41;28 - 00;00;42;27  Yeah, it's my pleasure.     00;00;44;06 - 00;01;03;27  Great. Well, looking forward to it. And we are going to be talking about some amazing stuff as always. But we also always like to get a feel for the person behind that amazing stuff. So what did you want to be when you grew up and how did you get from there to the field of clinical trials and technology and the kind of things you're doing now?     00;01;04;06 - 00;01;13;12  It depends on how far back you want to go, but I think that through most of my childhood, I probably wanted to be a like a professional trading card game player as.     00;01;16;03 - 00;01;17;28  Are you a Pokemon man or.     00;01;18;11 - 00;01;29;24  It was it was all of the above, right? It was like a Pokemon journey. Then there was like a, you know, journey. Then there was a magic. The Gathering journey. I kind of cycled through all of them, but I ended up landing on magic, I think, for most of it.     00;01;30;15 - 00;01;32;25  Well, check those old cards. You could be a millionaire.     00;01;33;01 - 00;01;39;12  I've been. I've been watching the the price of Charizard skyrocket with a lot of energy. You remember having plenty of money?     00;01;39;23 - 00;01;43;08  Well, great. Yeah, but obviously that's not what you wound up doing full on.     00;01;43;23 - 00;02;12;07  No, not at all. Ye

What does a data hippie believe about the democratization of data? What role do technology companies, government, academia, industry, and other stakeholders play in life sciences and discovery? And how might walking clinical trials lead to improved precision medicine? We will get the answers to those questions and more in this episode with Dr. Chris Boone, the GVP of Research Services at Oracle Life Sciences. Chris has held some prominent roles at AbbVie and Pfizer, influencing health economics, medical epidemiology, and real-world data and evidence. He is an adjunct assistant professor at NYU, engaged in national health data committees, and serves on several boards including the American Heart Association. -------------------------------------------------------- Episode Transcript: 00;00;00;03 - 00;00;22;00  What does a data hippie believe about the democratization of data? What role should tech companies, government and other stakeholders play in life sciences? Discoveries? And how might walking clinical trials lead to improved precision medicine? We'll get those answers and more on this episode of Research and Action in the lead.     00;00;24;03 - 00;00;43;21  Hello and welcome to Research and Action, brought to you by Oracle Life Sciences. I'm Mike Stiles. And today we're going right to the source when it comes to finding out what Oracle is doing in the life sciences space, what does a company like Oracle have to contribute? Why is it in the space? What does it and the rest of us have to gain from its involvement?     00;00;43;21 - 00;01;09;03  Those are the kinds of questions will be throwing at Dr. Chris Boon, newly appointed EVP of Research Services at Oracle Life Sciences. Chris has held some prominent roles at AbbVie and Pfizer, influencing health economics, medical epidemiology and real world data and evidence. He is an adjunct assistant professor at NYU, engaged in national health data committees and serves on several boards, including the American Heart Association.     00;01;09;03 - 00;01;14;18  So Chris, you're obviously a very busy person, so we really appreciate your time today.     00;01;15;21 - 00;01;17;02  Thanks, Mike. I'm happy to be here.     00;01;17;11 - 00;01;30;01  Before we get started,

What is the rare Gaucher disease and how does it impact patients, families, and life sciences? Is enough emphasis being placed on research and discovery for rare diseases? And what are the patient-centered approaches that best serve those battling rare diseases? We will get those answers and more in this episode with Tanya Collin-Histed, CEO of the International Gaucher Alliance. Tanya has been a longtime driving force in supporting patients with rare diseases and advocating for world-class healthcare. Her work has been nothing short of groundbreaking and she's become the go-to person for patients, medical practitioners, industry, and governing bodies. As a mother of a child with Gaucher disease, she brings a unique, first-hand, and compassionate approach.   -------------------------------------------------------- Episode Transcript:  00;00;00;00 - 00;00;25;09  What is the rare gosh disease? Is enough emphasis being placed on rare diseases? And what are the patient centered approaches that best serve those battling rare diseases? We'll get those answers and more on research in action in the lead to the world. Hello and welcome to another episode of Research and Action, brought to you by Oracle Life Sciences.     00;00;25;09 - 00;00;49;25  I'm Mike Stiles. And today we have a truly inspiring guest. Tanya calling his dad, CEO of the International Gosh Alliance, has been a long time driving force in supporting patients with rare diseases and advocating for world class health care. Our work has been nothing short of groundbreaking. She's actually become quite the go to person for patients, medical practitioners, industry governing bodies.     00;00;50;03 - 00;00;52;01  Tanya, thanks so much for being with us today.     00;00;52;14 - 00;00;55;04  Thanks, Mike. It's an absolute pleasure to be here.     00;00;55;19 - 00;01;05;11  Well, before we get into the incredible work you're doing, let's get a baseline understanding of exactly what Gaucher disease is and just how rare it is.     00;01;06;00 - 00;01;37;11  Okay. Well, as a caregiver, I'll give a lay lay version to you. So it's a genetic condition and it's inherited. It's caused by a storage disorder. And that is because people with Gaucher have a deficiency in an enzyme. And the function of that enzyme is that it's in the body to break down substances. And because there isn't enough of that enzyme, the substances store in different parts of the body.     00;01;37;25 - 00;02;05;17  And it really does depend on what type of disease you have to how the disease affects you. But all patients can have a large liver and spleen. They get anemia, they get bruising where the blood doesn't clot properly and bone pain and bone damage due to the cells being in their bone marrow where which is where the blood cells are made.     00;02;06;02 - 0

What is the rare Gaucher disease and how does it impact patients, families, and life sciences? Is enough emphasis being placed on research and discovery for rare diseases? And what are the patient-centered approaches that best serve those battling rare diseases? We will get those answers and more in this episode with Tanya Collin-Histed, CEO of the International Gaucher Alliance. Tanya has been a longtime driving force in supporting patients with rare diseases and advocating for world-class healthcare. Her work has been nothing short of groundbreaking and she’s become the go-to person for patients, medical practitioners, industry, and governing bodies. As a mother of a child with Gaucher disease, she brings a unique, first-hand, and compassionate approach.

International Data Corporation reports safety caseloads are increasing by 30% to 50% each year, and emerging technology will be the only way to keep up. But how are powerful technologies like generative AI advancing safety and pharmacovigilance? Is touchless case processing a good or bad thing? And how do we balance AI, automation, and the human touch? We will get answers to those questions and more in this episode with Bruce Palsulich, Vice President of Safety Solutions at Oracle Life Sciences. His portfolio includes Argus Safety, the industry-leading adverse event case processing and analytics solution, and Empirica Signal, the standard for signal detection and risk management. He has more than 30 years of experience in the healthcare and life sciences industry, including 25 in pharmacovigilance.    -------------------------------------------------------- Episode Transcript: 00;00;00;00 - 00;00;13;22 What is pharmacovigilance? How can technology best handle the tracking of adverse drug events? And is touchless case processing a good or a bad idea? We'll get those answers and more on this episode of Research in Action.   00;00;15;01 - 00;00;18;28 The lead, the Building.   00;00;20;10 - 00;00;48;22 Hello, welcome to Research in Action, brought to you by Oracle Life Sciences. I'm Mike Stiles. Today we are talking with Bruce Palsulich, vice president of Safety Solutions at Oracle Life Sciences. Bruce's portfolio includes Argus Safety, the industry leading adverse event, case processing and analytics solution, and empirical signal, the standard for signal detection and risk management. He's got more than 30 years of experience in the healthcare and life sciences industry, including 25 and pharmacovigilance.   00;00;49;02 - 00;01;03;25 Now, why is that important? Well, International Data Corporation reports safety caseloads are increasing 30 to 50% each year. Bruce is intimately involved in tackling that volume. So, Bruce, thanks for thanks for being with us today.   00;01;04;05 - 00;01;06;00 Yeah, thanks, Mike. Happy to be here.   00;01;06;16 - 00;01;17;04 Yeah. Let's get acquainted with you first. How did Life's path bring you into life sciences technology? How did you kind of wind up at Oracle and what are you tasked with getting done there?   00;01;17;29 - 00;01;50;08 You know, back back when I was still in university, I actually started off doing software development and consulting with a medical device company. And so early in my career, it was working on the actual embedded software that controlled medical devices. And early on ended up joining a consulting firm that started off doing engineering, consulting on medical devices, and eventually working towards quality software and regulatory submissions.   00;01;50;24 - 00;02;17;04 And so came to Oracle in 2009. So we had acquired a company that was that small engineering startup that I mentioned. And this is the company that originally developed Argus Safety, so I

How is clinical research becoming more patient-focused and more convenient for patients to participate in clinical trials? Why is a decentralized approach especially important concerning rare diseases? And how will digital innovation advance the way clinical research is conducted? We will learn those answers and more in this episode with Scott Schliebner, an innovative life sciences executive with 30 years of experience across the biopharma, CRO, medtech, and non-profit sectors. With a strategic and consultative approach to building and growing life science businesses, Scott has developed relationships, partnerships and collaborations that have driven commercial success. His vast experience includes leveraging real-world data and real-world evidence (RWE/RWD), leading technological innovation, and driving patient-focused paradigms to accelerate clinical drug development. Scott is an active board member, advisor, and mentor and his passions lie with infusing data and innovation into life sciences organizations—especially where rare diseases are concerned. He is currently the leading executive at Rare Clinical. -------------------------------------------------------- Episode Transcript: 00;00;00;07 - 00;00;24;21  How is clinical research becoming more patient focused and more convenient for patients to participate in? Why is a decentralized approach especially important when researching rare diseases? And what is the most likely future for how clinical research is conducted? We'll get the answers to all that and more on Research in Action.     00;00;24;23 - 00;00;48;24  Hello and welcome back to Research in Action, brought to you by Oracle. I'm Mike Stiles and our guest today is Scott Schliebner. Scott is a leader and innovative life sciences executive with 30 years experience across biopharma, CROs, medtech, and nonprofit. He's developed relationships, partnerships and collaborations that have driven commercial success with a strategic and consultative approach to building and growing life science businesses.     00;00;48;27 - 00;01;16;06  Scott got a lot of experience, including leveraging real-world data and real-world evidence, leading technological innovation and driving patient focused paradigms to accelerate clinical drug development. And he's an active board member, advisor and mentor, and he's all about infusing data and innovation into life sciences organizations, especially where rare disease is are concerned. And last but certainly not least, Scott is the leading executive at Rare Clinical.     <p class="Paragraph SCXW188870607

How is academia fostering research that later turns into startup companies? What are new computational powers bringing to in silico drug design? And what is MoveableType methodology and why should pharma be excited about it? We will learn those answers and more in this episode with Lance Westerhoff, President and General Manager of QuantumBio. QuantumBio is a biotech startup operating in the vast field of drug discovery and molecular design. As President and GM, Lance oversees QuantumBio's day-to-day management including the research, development, and deployment of advanced technology, as well as strategic partnerships and business development. Lance earned his PhD in Chemistry at Penn State University, and he is an entrepreneur, computational biochemist, and published scientist with projects involving the synergistic application of quantum mechanics and molecular mechanics in the life and pharmaceutical sciences. QuantumBio recently earned a Small Business Innovation Research (SBIR) grant from the NIH to run calculations for their MovableType methodology research, which they will be working with Oracle on that research project, and we talk about that and much more in this episode.   --------------------------------------------------------   Episode Transcript: 00;00;00;00 - 00;00;26;06 How was academia fostering research that later turns into startup companies? What are new computational powers bringing to in Silico drug design and what is moveable type methods? And why should pharma be excited about it? We'll get those answers and more on research and action in the lead. The leading scene. Hello and welcome to Research and Action, brought to you by Oracle for Research.   00;00;26;06 - 00;01;00;18 I'm Mike Stiles. And today our guest is Lance Wester Hof, who is president and general manager of Quantum Bio. That's a biotech startup that operates in the field of drug discovery and molecular design. Lance oversees day to day management, including the research, development and deployment of advanced technology, as well as strategic partnerships and business development. He earned his Ph.D. in chemistry at Penn State, and he's an entrepreneur, a computational biochemist and published scientist with projects involving the synergistic application of quantum mechanics and molecular mechanics in the life and pharmaceutical sciences.   00;01;00;20 - 00;01;24;09 In fact, Quantum Bio earned a small business innovation research grant from the NIH to run calculations for their movable type methodology. Research. They'll be working with Oracle on that project. So, Lance, we're really glad to have you with us. Certainly. Well, thank you for having me. I look forward to the discussion. Well, listeners, I hope you're ready to get into the weeds because we're going to get

What are the 17 United Nations Sustainable Development Goals? What are the biggest challenges in pursuing and achieving those goals? How does technology play a role? And what's the best way for government, academia, and industry to cooperate and collaborate in support of fundamental research? We will learn those answers and more in this episode with Declan Kirrane, the Chairman of the Science Summit at the United Nations General Assembly, and founder and managing director of ISC Intelligence in Science. Declan has more than 25 years of experience as a global senior advisor to governments and industry on science research, science policy and related regulation. He has been actively promoting a more significant role for science within the context of the United Nations General Assembly since 2010. This has culminated in the annual Science Summit within the context of the UN's General Assembly. The focus of the Summit is on the role and contribution of science to attain the United Nations Sustainable Development Goals – or SDGs. The current edition – UNGA78 - takes place from September 12-29, and will bring together thought leaders, scientists, technologists, policymakers, philanthropists, journalists, and community leaders to increase health science and citizen collaborations to promote the importance of supporting science. And we are thrilled that Oracle will be part of the Science Summit with a few of our executives speaking and attending, including Alison Derbenwick Miller, global head and VP of Oracle for Research.   -------------------------------------------------------- Episode Transcript: http://traffic.libsyn.com/researchinaction/Research_in_Action_S01_E19.mp3   00;00;00;00 - 00;00;22;29 What are the United Nations Sustainable Development Goals? What are the biggest challenges in pursuing and achieving those goals? And what's the best way for government, academia and industry to cooperate and collaborate in support of basic research? We'll get the answers to all this and more on Research in Action.   00;00;23;02 - 00;00;49;08 Hi, and welcome back to Research and Action, brought to you by Oracle for Research. I'm Mike Stiles and today's distinguished guest is Declan Kirrane, who is the chairman of the Science Summit at the United Nations General Assembly and the founder and managing director of ISC Intelligence and Science. And we're talking to a guy with more than 25 years of experience as a global senior advisor to governments and industry on science research, science policy and regulation around science.   00;00;49;10 - 00;01;17;07 Declan has been promoting a bigger role for science in the context of the U.N. General Assembly since 2010, and that's led to an annual scie

How is computer vision being used to spot autism symptoms much earlier in children? What is augmented cognition? And how can you use AI to make data models work even with small data sets? We will learn those answers and more in this episode with Dr. Sarah Ostadabbas. Dr. Ostadabbas is an associate professor in Electrical and Computer Engineering at Northeastern University, where she is also the director of the Augmented Cognition Laboratory (ACLab), which works at the intersection of computer vision, pattern recognition, and machine learning. Before joining Northeastern, she was a post-doctoral researcher at Georgia Tech and earned her Ph.D. at the University of Texas at Dallas. A renowned expert in the field, her research focuses on the goal of enhancing human information-processing capabilities through the design of adaptive interfaces based on rigorous models using machine learning and computer vision algorithms. With over 100 peer-reviewed publications, Professor Ostadabbas has received recognition and awards from prestigious government agencies such as the National Science Foundation (NSF), the Department of Defense (DoD) as well as several private industries. In 2022, she received an NSF CAREER award to use artificial intelligence for the early detection of autism, which she is working on with Oracle for Research. http://www.oracle.com/research   ---------------------------------------------------------   Episode Transcript:   00;00;00;00 - 00;00;26;15 How are computer vision and contactless techniques spotting signs of autism much earlier in children? What is augmented cognition and how can you use AI to make data models work, even with small datasets? We'll find all that out and more in this episode of Research in Action. Hello and welcome back to Research in Action, brought to you by Oracle for Research.   00;00;26;15 - 00;00;50;10 I'm Mike Stiles, and today we have with us Dr. Sarah Ostadabbas, an Associate Professor in the Electrical 00;50;13 - 00;01;24;04 Her research looks at how we can enhance human information processing capabilities by designing adaptive interfaces based on rigorous models using machine learning and computer vision algorithms. With over 100 peer reviewed publications. Professor Ostadabbas has received recognition and awards from government agencies like the National Science Foundation, the Department of Defense and se

How do the latest technologies impact epidemiology, clinical research, and public health? What kind of progress has there been in collaboration, open data, and citizen science? And in what ways can digital health appropriately supplement healthcare with the human touch? We will get the answers to these questions and more in this episode with Christine Ballard, a professionally trained epidemiologist specializing in clinical research and a Research Advocate at Oracle for Research. Christine has her Master of Public Health and is currently pursuing her Ph.D. in pharmacoepidemiology at UNC Chapel Hill. Her vast experience includes stints as an assistant professor and clinical research roles at Wake Forest Baptist Health, the University of Rochester Medical Center, and the New York State Department of Public Health. You can learn more about Oracle for Research here: http://www.oracle.com/research   --------------------------------------------------------   Episode Transcript: 00;00;00;00 - 00;00;24;21 What challenges do epidemiology researchers face in getting solutions to the public? What kind of progress has there been in collaboration, open data and citizen science? And in what ways can digital health appropriately supplement health care with the human touch? We'll get the answers to these questions and more on this episode of Research in Action, brought to you by Oracle for Research.   00;00;24;23 - 00;00;57;18 Hello. Welcome back to another episode of Research in Action, brought to you by Oracle for Research. I'm Mike Stiles, and today we have Christine Ballard with us. Christine is a professionally trained epidemiologist, specialized in clinical research. She has her master of public health and is working on her Ph.D. and pharmacoepidemiology at UNC-Chapel Hill. Her rather vast background includes stints as an assistant professor and clinical research roles at Wake Forest Baptist Health, University of Rochester Medical Center, and the New York State Department of Public Health.   00;00;57;20 - 00;01;26;08 She's currently a research advocate at Oracle for Research. And we're going to learn what those research advocates do and get into a lot more. Thanks for being with us, Christine. Thank you so much, Mike. I can't wait to dive into this. Oh, yeah. I'm looking forward to it as well. And I am going to ping you with questions about clinical research, epidemiology, pharmacoepidemiology as I keep tripping over that word, probably where is what kind of shape health care is in.   00;01;26;09 - 00;01;48;12 We're going to talk about that and some other stuff. But first, what got you as a person interested in

How do you connect the needs of researchers to the capabilities of technology? What are the main stages of research and the challenges faced at each stage? And will AI and machine learning speed up research and get solutions to market faster? We will learn those answers and more in this episode with Dr. Mark Hoffman, the Chief Research Information officer for Children's Mercy and the Children's Mercy Research Institute, a position he has held since 2016. Dr. Hoffman earned his doctorate in Bacteriology from the University of Wisconsin-Madison. He later joined Cerner as a software engineer where he advanced to the role of Vice President for Genomics and Research. Dr. Hoffman was also part of the faculty at the University of Missouri Kansas City (UMKC) in the Departments of Biomedical and Health Informatics and Pediatrics. His formal training in research and experience in software development has prepared him to connect the needs of researchers to the capabilities of technology. His work is focused on identifying the best capabilities possible to meet rapidly changing requirements in genomics, public health, and big data. Dr. Hoffman is an inventor of 22 issued patents, a member of the American Academy of Inventors, a TED talk alumnus, and an award-winning healthcare product developer. You can learn more about Dr. Hoffman and Children's Mercy here: https://www.childrensmercy.org Learn more about Oracle for Researcher here: http://www.oracle.com/research ---------------------------------------------------------- Episode Transcript 00;00;00;00 - 00;00;26;02 What are the three main stages of research and the challenges each are facing? How are researchers handling the new federal policies around data sharing? And will AI and machine learning speed research and get solutions to market faster? We'll get those answers and more on this episode of Research in Action. Hello and welcome back to Research in Action, brought to you by Oracle for Research.   00;00;26;02 - 00;00;49;21 I'm Mike Stiles. And today our guest is Dr. Mark Hoffman, who is the Chief Research Information Officer for Children's Mercy and the Children's Mercy Research Institute. That's a position he's held since 2016. Dr. Hoffman earned his doctorate in bacteriology from the University of Wisconsin-Madison and later joined Cerner as a software engineer, where he went on to be Vice President for genomics and research.   00;00;49;24 - 00;01;17;11 Dr. Hoffman was also part of the faculty at the University of Missouri, Kansas City, and the Departments of Biomedical and Health Informatics and Pediatrics. Now, because he's had formal

How can researchers who have developed innovative solutions begin to commercialize? What makes a great research-entrepreneur? And how are universities and organizations helping to bridge the research-to-commercialization gap? We will learn those answers and more in this episode with Laure Haak. A neuroscientist by training, Laure has a BS and MS in Biology and Ph.D. in Neuroscience from Stanford University, and she did postdoctoral work at the National Institutes of Health. Her career includes diverse experiences: serving as founding Executive Director of ORCID; leadership roles at Thomson Reuters, The US National Academies, and Science Magazine. She is currently founder and CEO of Mighty Red Barn, a consultancy that supports impact-based organizations building digital infrastructure, and helping research innovators go from discovery to startup. Laure carries on this work as a Research Scholar at the Ronin Institute, and Board Chair of Phoenix Bioinformatics and the Green Bay Chapter of SCORE. You can learn more about Laure and Mighty Red Barn here: https://www.mightyredbarn.com Learn more about Oracle for Research: http://www.oracle.com/research    --------------------------------------------------------- Episode Transcript 00;00;00;00 - 00;00;26;12 How can researchers who have developed innovative products begin to commercialize them? Why are digital persistent identifiers important to researchers? And who are some of the partners that can help researchers get their products to market? We'll get those answers and more on this episode of Research and Action. Hello again. Welcome back to Research in Action, brought to you by Oracle for Research.   00;00;26;12 - 00;00;47;27 I'm Mike Stiles. And our guest today is Laure Haak. Laure is a neuroscientist by training. She has a B.S. and M.S. in Biology and a Ph.D. in neuroscience from Stanford. And she did her postdoctoral work at the National Institutes of Health. She's done a lot over the course of her career, including serving as founding executive director of ORCID leadership roles at Thomson Reuters,   00;00;48;00 - 00;01;14;09 the U.S. National Academies, and Science magazine. She's currently founder and CEO of Mighty Red Barn. That's a consultancy that supports impact-based organizations that are trying to build their digital infrastructure. And it also helps research innovators like many of our listeners, get from discovery to startup. Laure carries on this work as a research scholar at the Ronin Institute and Board chair of Phoenix Bioinformatics and the Green Bay chapter of SCORE.   00;01;14;09 - 00;01;38;01 <p class

What is in silico drug design? And what role is it playing in drug discovery? How is cloud computing removing the limitations for in silico screening? We will learn those answers and more in this week's episode with Dr. John Bruning, a Senior Lecturer in the School of Biological Sciences at the University of Adelaide in Southern Australia, where he also founded the University's laboratory of protein crystallography. Dr. Bruning is also an Oracle for Research Fellow and was named a finalist for the 2022 Oracle Excellence Award in the Eureka Award category. Dr. Bruning received his Bachelor of Science from Texas A&M University and his PhD from Rice University. He has completed two post-doctoral research positions in structure guided drug design at the Scripps Research Institute and the Texas A&M Health Science Center in the Houston Medical Center. His research has been cited in numerous peer-reviewed journals. You can learn more about Dr. Bruning and his work here: https://researchers.adelaide.edu.au/profile/john.bruning Learn more about Oracle for Research: http://www.oracle.com/research

How did we get where we are today with AI and machine learning? What are the ways Large Language Models (LLMs) can be applied to healthcare? And what about that suggested pause on advanced AI? We will explore those questions and much more in this episode with Dr. James Benoit, a postdoctoral researcher at the Women and Children's Health Research Institute (WCHRI) in Canada, where his research focuses on the use of Large Language Models (LLMs) and artificial intelligence to improve healthcare outcomes. He earned his Bachelor's and Master's from the University of British Columbia, where he studied Applied Ethics and Integrated Science; and he earned his PhD in Psychiatry at the University of Alberta. He has years of research experience, including time as a Research Fellow at Harvard Medical School. His current work involves leveraging large language models (LLMs), such as GPT-4, to develop tools for clinical decision-making and patient care.

What is carbon capture and storage and how can it help fight climate change? Why should we be more excited about earth worms and research advocates? And how is cloud computing tying it all together for better global health? We’ll explore those issues and more in this episode with Dr. Ryan Payton, a Senior Research Advocate for Oracle, and an environmental scientist. Ryan earned his PhD at Royal Holloway, University of London, in Geological and Earth Sciences, where his research focused on the potentiality of subsurface geological carbon storage reservoirs, of which he collaborated with Oracle. This episode tackles climate change and the many research areas, like carbon capture and storage, that are helping in our fight against climate change for better global health.

How can patients and their families become more integral in the research process and drug discovery? How can citizen scientists and patient-led research become more accepted in the scientific community? And who qualifies as a citizen scientist? We will tackle those questions and much more in this episode with Amy Dockser Marcus, a Pulitzer Prize-winning journalist and author of the recently published book, "We The Scientists: How a daring team of parents and doctors forged a new path for medicine." Amy is a veteran reporter at the Wall Street Journal and won her Pulitzer Prize for Beat Reporting in 2005 for her series of stories about cancer survivors and the social, economic, and health challenges they faced living with the disease. She has covered science and health at the Journal for years, and she also earned a Master of Bioethics from Harvard Medical School. Learn more about Amy and her new book: https://www.wsj.com/live-qa/amy-dockser-marcus-on-her-new-book-we-the-scientists/4BFE8957-882E-4C93-B335-7151B8411310

What are the obstacles to faster pharmaceutical and medical research? And is there such a thing as a comprehensive biomedical search and AI engine? We will learn those answers and more with guest Matteo Ghetti, cofounder of Sweden-based startup PapersHive. PapersHive is a biomedical search and AI engine to help researchers and medical professionals get to scientific research evidence faster. And this matters a lot with the emergence of evidence-based medicine making R&D in drug development and medical device design more arduous, demanding researchers to consult many tens, hundreds, or thousands of scientific publications. We also talk about Matteo and his co-founders' journey from ideation to a disruptive startup. We are proud that Oracle for Research has played a role in the PapersHive journey. Learn more about how Oracle for Research can help you speed up your research with grants, cloud computing, and hands-on support and expertise: http://www.oracle.com/research

How is machine learning helping orthopedic surgeons predict better outcomes for patients? And how can those algorithms help predict how bone fracture surgery is approached? We will get those answers and much more on this episode with Dr. Akash Shah, Resident Physician in the Department of Orthopaedic Surgery at UCLA Medical Center. Dr. Shah received his Bachelor of Science at Duke University, and he went on to graduate from Harvard Medical School. He is also part of the team in the Department of Orthopaedic Surgery at the University of California, Los Angeles, that is working with international collaborators to build advanced machine learning (ML) models for hip and long bone fractures research. Dr. Shah and team received a grant from Oracle for Research to advance their research using Oracle Cloud to run high-powered ML models. Learn more about how Oracle for Research can help you speed up your research with grants, cloud computing, and hands-on support and expertise: www.oracle.com/research

How is Open Data and Open Science being encouraged and nurtured across the global research community? What are the biggest challenges and benefits? And how are industry players like Oracle helping? We'll be exploring those questions and much more with Hilary Hanahoe, Secretary General of the Research Data Alliance (RDA). RDA is a global community-driven organization with the goal of building the social and technical infrastructure to enable open sharing and re-use of data. As Secretary General, Hilary's responsibilities include leadership of RDA's membership, management of the RDA organization, engagement with stakeholders, and sustainable stewardship of their high-impact global community. Oracle is a member of the RDA and is currently undergoing research projects with the RDA to advance industry best practices and promote FAIR data principles. Learn more about how Oracle for Research can help you speed up your research with grants, cloud computing, and hands-on support and expertise. http://www.oracle.com/research. Learn more about the RDA: https://rd-alliance.org

What is Human Activity Recognition and why is it so important for Parkinson's research? What is the relationship between freezing of gait or FOG and brain circuitry? And how are edge computing, wearables, AI, and self-reporting helping researchers in the fight against Parkinson's? We'll be exploring those questions and much more with two Emory University professors focused on better understanding Parkinson's to help push toward a cure. Dr. Lucas McKay is an Assistant Professor of Biomedical Informatics and Neurology at the Emory University School of Medicine. He also holds a courtesy position and receives funding from the Biomedical Engineering Department at Emory/Georgia Tech. Dr. Hyeok Kwon is a post-doctoral fellow at the Department of Biomedical Informatics at Emory University and received his Ph.D. in computer science at the School of Interactive Computing at Georgia Tech. His research is focused on human-centered artificial intelligence systems and the application of computational analysis in the domain of health-related behaviors. The two were recently awarded an Oracle for Research cloud computing award to further their research around Parkinson's disease. Learn more about how Oracle for Research can help you speed up your research with grants, cloud computing, and hands-on support and expertise. http://www.oracle.com/research

What was it like to keep research work going during the worst of the pandemic? And how close are we to a vaccine that works against all current and future coronavirus variants? We will discuss that plus biochemistry, biosystems, and in silico design in this episode with Dr. Imre Berger. Dr. Berger is a professor of Biochemistry at the University of Bristol; Director for the Max Planck Bristol Centre for Minimal Biology; and co-founder and chief strategy officer at Halo Therapeutics, a University of Bristol spin-out. He has been published in countless scientific and academic journals, and his work covers multiple areas of biochemistry. His recent work has been focused on coronaviruses, specifically developing pan-coronavirus antivirals at Halo Therapeutics. Learn more at www.halo-therapeutics.com Learn more about how Oracle for Research can help you speed up your research with grants, cloud computing, and hands-on support and expertise. www.oracle.com/research

How are humanist researchers approaching the gathering and accessibility of vast amounts of data? And are researchers in the humanities going a little too far in relying on automation? We’ll tackle those questions – plus explore the historic and remarkable digitization of the Slave Voyages project – with Dr. John Mulligan, a professor in the Center for Research Computing and the Humanities Research Center at Rice University in Houston. Dr. Mulligan helps humanists make the most of Rice's IT infrastructure and the latest technologies to help their big ideas go bigger and faster. Dr. Mulligan recently won an Oracle Excellence Award in the Eureka category, which honors the top global researchers working with Oracle Cloud infrastructure, winning the award for his historic and remarkable work on the Slave Voyages project. Visit www.slavevoyages.org to learn more. Also, learn more about how Oracle for Research can help you speed up your research with grants, cloud computing, and hands-on support and expertise. www.oracle.com/research

A vital medical imaging technique is getting a major reconstruction, thanks to researchers at the University of Texas at Austin. Assistant Professor Jon Tamir and his team at the University of Texas at Austin are developing fast, robust, and standardized MRI reconstruction methods for faster and cheaper diagnosis and monitoring that can be used across many institutions with disparate system hardware and clinical needs. This is our Oracle for Research short that gives you a download on exciting research in only two minutes.

What happens when data science meets cell biology? One researcher at the University of Bristol is finding out. Ioana Gherman, PhD student at the University of Bristol, is applying mathematical modeling and machine learning to create and analyze whole-cell models – learn how in this mini episode. This is our Oracle for Research short that gives you a download on exciting research in only two minutes.

What is it going to take to achieve major advancements in neurodegenerative diseases like Parkinson's, and how far have we actually gotten in mapping the entire human brain? We'll answer those neuroscience questions and more with neuroscientist and PhD Bryan Barker. Bryan works as a Research Advocate for Oracle for Research, Oracle's program dedicated to simplifying the research process to accelerate discovery for researchers. As a Research Advocate, Bryan serves as a scientific collaborator and technology advisor to researchers to speed up time to science. In this episode, Bryan discusses advancements in Parkinson's disease and where he hopes to speed up discovery, as well as other dementia diseases including Alzheimer's disease. We also discuss how far we've actually gotten in mapping the human brain. The show tackles some fascinating and mind-blowing aspects of brain science and how cloud computing and technology is allowing researchers to understand our brain much faster than we ever thought possible. Learn more about how Oracle for Research can help you speed up your research with grants, cloud computing, and hands-on support and expertise from Research Advocates like Bryan. www.oracle.com/research