Ask Doctor Dawn

Broadcast from KSQD, Santa Cruz on 7-09-2026: Researchers refined a technique to reverse skin cell aging by about 30 years while preserving cellular identity. Exposing adult fibroblasts to Yamanaka factors—stopping before full reversion to pluripotent stem cells,reset the epigenetic clock and gene expression patterns to resemble much younger cells. The rejuvenated fibroblasts produced significantly more collagen, migrated faster to close artificial wounds, and showed reversal of gene expression patterns associated with Alzheimer's and cataracts. Since long-term epidemiologic data doesn't yet exist, Dr. Dawn follows up on last week's vaping question by exploring cancer mechanisms. Vaping aerosols impair DNA repair fidelity while triggering IL-6, IL-8, and TNF-alpha secretion. Nicotine-derived nitrosamines, reactive carbonyls (formaldehyde, acetaldehyde, acrolein) are generated when propylene glycol and vegetable glycerin are heated. Upregulated cytochrome P450 enzymes convert precarcinogens like benzopyrene into carcinogens. Mice exposed for 54 weeks developed lung adenocarcinomas in 22% and precancerous bladder hyperplasia in 57%, with markers matching those show predict lung cancer years before diagnosis. The Mexican Biobank—which includes over 40,000 samples from all 31 Mexican states revealed dramatic regional variation in drug-metabolism genes driven by Indigenous ancestry. In Chiapas, nearly 40% of the population carries two copies of a CYP2D6 variant reducing fentanyl metabolism, versus just 10% in Sinaloa. The SLCO1B1 variant hindering statin metabolism is found in over 15% of Yucatán residents., where 8 million Mexicans take statins. Dr. Dawn discusses both the promise and potential dark side of population genetic testing, including UK plans to genotype all children at birth for inborn errors of metabolism. Dr. Dawn briefly revisits the recent Indian study showing conch-shell blowing reduces sleep apnea by 34%, comparing it to earlier didgeridoo research, both of which strengthen airway muscles through forced-blowing exercises. A caller from Capitola recovering from non-Hodgkin's lymphoma near the L5 nerve asks about Japanese Kampo medicine formulas (Goshajinkigan, Yokukansan) for post-treatment nerve pain. Dr. Dawn suggests the pain likely originates from scar tissue tethering the nerve, and recommends consulting the Oriental Medicine Doctor program at Five Branches in Santa Cruz where faculty can advise on herbal formulas that trace back thousands of years through cultural exchange between China and Japan. Dr. Dawn explains Lp(a):lipoprotein(a), a small protein string attached to LDL particles that promotes clumping and clotting, is a genetically-determined coronary artery disease and stroke risk factor invisible to standard lipid panels. Levels of 250 particles double coronary risk and 350 particles triple it. Less than 75 is normal. Two new pharmaceutical strategies are

Broadcast from KSQD, Santa Cruz on 7-02-2026: Dr. Dawn devotes the first half of the show to a nuanced defense of GLP-1 receptor agonists, arguing the polarized debate treats obesity as a moral failure rather than a physiological one. She recounts the "Marilyn Monroe dress" moment that transformed semaglutide from diabetes drug into elite cosmetic tool, and pushes back on the puritanical framing that behavior change must be earned rather than pharmacologically enabled—noting we don't apply this logic to antihypertensives or statins. Dr. Dawn catalogs visceral fat as a genuine endocrine organ producing over 17 hormones, most of which drive self-perpetuating growth: leptin (this satiety hormone at high levels disables it's own brain receptor), IL-6, TNF-alpha (blocks insulin), resistin (increases insulin resistance and inflammation), PAI-2 (blocks clot breakdown, raising cardiovascular risk), retinol-binding protein 4 (impairs muscle glucose uptake), chemerin (recruits macrophages and directs fat to the belly), and visfatin. Only adiponectin declines with rising visceral fat. It improves insulin sensitivity, suppresses hepatic gluconeogenesis, and blocks IL-6 . Dr. Dawn describes GLP-1's neurobiological action: receptors in the hypothalamus, brainstem, hippocampus, and mesolimbic reward system, with the drugs quieting the brain's salience network so food loses its intrusive pull. Taste buds shift, sweet and salty become muted, and reward circuits stop firing on cheat foods—creating a window during which behavioral change becomes possible. Dr. Dawn frames group support through self-determination theory (autonomy, competence, relatedness), arguing GLP-1s create the cognitive bandwidth for behavioral programs to succeed. A Tufts study of patients discontinuing after 10% weight loss found those enrolled in behavioral support programs regained about three times less weight than usual-care controls, outperforming even medically-tailored meal plans. Group engagement doubled the time patients stayed on the medication. A November 2025 Nature study piggybacked on deep brain stimulation research at Penn. Electrodes implanted in the nucleus accumbens of post-bariatric patients recorded low-frequency brain activity surges during food-noise episodes on drug free patients. A third participant who started tirzepatide showed complete silencing of that signature—the first direct electrical confirmation that GLP-1s suppresses compulsive food thoughts in the reward center. RNA sequencing of adipose tissue from 25 obese patients before and after bariatric surgery, compared to 24 lean controls, revealed persistent epigenetic changes even after weight loss. Lipid-associated inflammatory macrophages drop but retain some of their pro-inflammatory epigenetics, explaining the well-known slippery slope back to obesity—and why Dr. Dawn suggests GLP-1s may work best as intermittent tools when behavioral mainten

Broadcast from KSQD, Santa Cruz on 6-25-2026: Dr. Dawn devotes the show's opening to ivermectin for COVID. She walks through critical thinking principles—considering the source, cross-verification, and recognizing self-interested claims—before reviewing the evidence. The most-cited 2021 Bulgarian study of 300 people showing 77% reduction lacked accessible methods, and larger trials capable of detecting even small benefits failed to confirm efficacy. On safety, the standard 12mg parasitic dose every few weeks is well-tolerated due to the blood-brain barrier and efflux pumps that keep ivermectin out of the brain, but daily long-term dosing has caused encephalopathy, liver and kidney damage, and birth defects. Critical drug interactions—macrolide antibiotics, verapamil, proton pump inhibitors, and beta blockers—disable the efflux mechanism, and high-fat meals increase absorption 2.5-fold. Dr. Dawn shares two inflammation formulas calculable from any CBC. The Systemic Inflammatory Index (neutrophils × platelets ÷ lymphocytes) flags runaway inflammation: 200-500 is good, above 900 warrants investigation and correlates with worse stroke outcomes and rising tumor burden. The SIRI (neutrophils x monocytes ÷ lymphocytes) detects chronic tissue inflammation and early innate immune activation: below 500 is good, above 1500 indicates trouble and correlates with cardiovascular mortality and arterial plaque from M1 macrophage activity. Dr. Dawn shares two takeaways from the Institute for Functional Medicine annual conference: in patients at high cardiovascular risk by cholesterol, each gram daily of combined EPA/DHA produces a 9% risk reduction, with bruising as the dose-limit signal. Additionally, a 15-minute walk within 30 minutes of a meal nearly eliminates postprandial inflammation. An emailer asks whether an endocrinologist's claim that vitamin D leaches calcium from bones is true. Dr. Dawn confirms that very high vitamin D (above 150 nanograms, with concern starting above 90) elevates 1,25-vitamin D, which stimulates osteoclast formation and increases C-telopeptide markers of bone breakdown. A crowdsourced question asks how histamines work in women. Dr. Dawn explains histamine functions as a CNS neurotransmitter promoting alertness, wakefulness, and pain perception (deficient in narcolepsy), and as a GI signal driving acid secretion, motility, and visceral sensation. Gut bacteria can convert histidine to histamine, and fish left to spoil can trigger anaphylactic-like reactions from accumulated bacterial histamine. She notes stomach acid treatments Tagamet and Zantac are H2 blockers rather than the more familiar H1 antihistamines, and confirms histamine correlates with hormones but not particularly with minerals. A crowdsourced question on B vitamins for women in their mid-twenties prompts Dr. Dawn to recommend prenatal vitamins for those who might become pregnant, and B100 complex with cal

Broadcast on KSQD, Santa Cruz on 6-18-2026:>/p> Dr. Dawn opens with Virginia Tech research showing yellow fever mosquitoes can learn to associate DEET with blood meals after just four pairings, with over 60% of trained mosquitoes lunging at DEET alone. She emphasizes using DEET at sufficient concentration since under-application could teach mosquitoes a "life lesson" that compromises one of our best protections against malaria, dengue, and Zika. A controversial new theory from the University of Bonn proposes that iron-rich macrophages in the pigeon liver serve as the long-elusive magnetic compass. Pigeons given drugs that wiped out their liver macrophages became completely disoriented when released on a cloudy day, though critics argue the trace iron is too weakly magnetic and birds may have been agitated by the drug itself. A COVID-era crowd-movement study found that in 32 of 33 trials, people preferred to turn counterclockwise regardless of handedness or culture (Spain and Japan). Animals show no such bias, suggesting a uniquely human biochemical asymmetry—Dr. Dawn speculates this may relate to left-hemisphere language centers near the inner ear, and notes racetracks worldwide run counterclockwise. A caller in Ben Lomond reports mouth irritation from FYGG nanohydroxyapatite toothpaste. Dr. Dawn suspects bystander ingredients (flavorings, paste-consistency agents) rather than the hydroxyapatite itself—which acts as remineralizing "grout" filling tiny tooth cracks—and recommends switching to a different fluoride-free brand like Tom's after the caller confirmed reaction on rechallenge. The same caller asks about turmeric liver toxicity. Dr. Dawn explains that reputable companies following good manufacturing practices stay within 5-10% accuracy on dosing, and her recommended dose (one teaspoon turmeric, one-eighth teaspoon black pepper, around 5g daily) stays far below toxic levels. Curcumin inhibits NF-kappa-B, the master switch for inflammatory cascades. An emailer in Bonny Doon asks about treating chemotherapy-induced peripheral neuropathy. Dr. Dawn recommends electrical acupuncture which works more than half the time, combined with methylated B12 (2,000 micrograms daily), methylated folate (1,000 micrograms twice daily), alpha lipoic acid (300mg twice daily, also effective for tinnitus), and acetyl-L-carnitine (1,500mg daily). She also recommends photomodulation devices using 635nm red light with near-infrared. A caller raises magnetic field effects on humans. Dr. Dawn discusses human adaptability, referencing Chernobyl black moths that increased melanin epigenetically and ongoing efforts to upregulate radiation-resistance genes via mRNA for future space travel. The conversation turns to evolution of unique human hair patterns, with Dr. Dawn proposing sexual selection (armpit/pubic hair for pheromones) and neoteny (women's facial smoothness resembling infants triggering pro

Broadcast from KSQD, Santa Cruz on 6-11-2026: Dr. Dawn discusses fascia — the gelatinous network of sugary proteins, salts, and collagen bundles that has been known to acupuncturists and osteopaths for millennia but ignored in conventional medical training. New confocal laser endomicroscopy technology has finally visualized this "interstitium" as a fluid-filled space draining to lymph nodes, present throughout the GI tract, urinary bladder, dermis, and peribronchial tissues. The structure may play roles in cancer metastasis, edema, fibrosis, and mechanical tissue function. An emailer asks about elevated organic arsenic levels (from sardines) and ultra-filtered dairy. Dr. Dawn explains that arsenobetaine—the protein-bonded form found in fish, is harmless and passes through the body, while inorganic and methylated arsenic accumulate in bone and collagen-rich tissues. In a second question about the safety of ultrafiltered dairy, she notes ultra-filtered products may carry more microplastics from extensive plastic filters and tubing exposure, with aged cheese being particularly concentrated since water removal increases plastic density. An emailer asks about breast MRI contrast options. Dr. Dawn explains that breast MRI requires gadolinium contrast because tumors leak through their poorly-formed blood vessels, creating necessary visual contrast. She strongly recommends macrocyclic gadolinium (a stable birdcage structure) over the linear form, which slips into bones, skin, the brain's caudate nucleus, liver, and spleen for at least eight years and rarely, can cause nephrogenic systemic fibrosis. There is some suggestion it may trigger brain inflammation. She suggests listing linear gadolinium as a drug sensitivity in medical charts. Researchers harvested exosomes from semen. The exosomes evolved to help sperm penetrate egg barriers, making them ideal delivery vehicles for drugs too toxic for traditional administration. These bubble-like vesicles can penetrate the eye to distribute a manganese dioxide nanozyme compound (CMG) across ocular barriers to treat retinoblastoma, a childhood eye cancer typically requiring eyeball removal. Researchers used extracellular vesicles (effectively artificial exosomes) delivered via nasal spray to reverse brain aging in mice. The vesicles carried messenger RNA targeting the NLRP2 inflammasome, restoring mitochondrial activity in neurons and improving memory and recognition in treated animals. The nasal delivery route bypasses the blood-brain barrier, opening possibilities for treating cognitive deterioration without injections or surgical implants. An emailer reports his wife two inches shorter at a new Kaiser facility in another state. Dr. Dawn first considers measurement inconsistency (shoes on or off), then suggests evaluating for compression fractures, disc disease, and parathyroid tumors. She recommends a bone scan, C-terminal telopeptide testin

Broadcast from KSQD, Santa Cruz on 6-04-2026: A caller with previously normal platelets now bouncing between 40-60 asks whether to accept her doctor's recommendation of high-dose dexamethasone. Dr. Dawn suggests checking homocysteine and methylmalonic acid for hidden B12 issues, getting an ultrasound to rule out splenic sequestration, and confirming actual autoimmune antibody testing before committing to steroids. Researchers invented a fake disease called "Bixonimania" (periorbital hyperpigmentation supposedly caused by blue light) with obvious tells including a fictional Asteria Horizon University and Starfleet Academy acknowledgment. By 2026, AI chatbots were routinely describing it as real, and three Indian researchers even cited the fake preprint in a peer-reviewed paper that was subsequently retracted. A 75-year-old caller asks about intermittent fasting patterns. Dr. Dawn advises against fasting longer than 24 hours after age 75 due to muscle catabolism, and recommends time-restricted eating instead—starting with protein at 10am to prevent muscle breakdown. For rebuilding lost muscle she prescribes resistance bands, 30g protein including 5g branched-chain amino acids before exercise, and total daily protein matching one's age in grams. A male caller with a T-score of -4.0 on DEXA (diagnostic of severe osteoporosis) asks about pulsed electromagnetic frequency therapy for his hip. Dr. Dawn explains bone's piezoelectric properties mean that compression and electrical stimulation both activate osteoblasts. She recommends checking parathyroid hormone (tumors cause silent calcium loss), notes that vitamin D above 10,000 IU daily can paradoxically activate osteoclasts and worsen osteoporosis. She discusses how decades of proton pump inhibitor use cause achlorhydria leading to both B12 deficiency (elevated MCV) and calcium malabsorption. The same caller asks whether AI has genuine empathy after seeing Claude express regret about military use, and Dr. Dawn explains AI is a statistical mirror — the illusion of empathy from frequency-based word selection trained on human text, not genuine feeling. Daraxonrasib, an oral monoclonal drug from Revolution Medicines, doubled survival time in metastatic pancreatic cancer trials from 7 to 13 months, prompting FDA expanded access. Dr. Dawn explains KRAS—the long-elusive target with no binding pockets—was finally tackled using Gregory Verdine's "molecular glue" approach, where small molecules first attach to bystander proteins to create complexes capable of binding KRAS. A high school in San Francisco has seen seven active and 241 latent TB cases since November 2025, with 18% of the school community infected. Dr. Dawn notes California reached a 12-year high of 2,150 TB cases in 2025, and connects the unusually high latent-infection rate to recent Medi-Cal cuts and immigration-related healthcare avoidance. She argues healthcare acce

Broadcast from KSQD, Santa Cruz on 5-21-2026: This is the second show featuring Mira Achilles, a UCSC graduate working on her masters in epidemiology. Dr. Dawn and Mira open with a Harvard study showing OpenAI's o1 reasoning model reached correct diagnoses 67% of the time versus 50-55% for physicians, and scored 89% versus 34% on treatment plans. The AI advantage shrinks when doctors get more data and time, suggesting its greatest value is in fast-moving triage. Dr. Dawn cautions that over-reliance on AI during residency could undermine the clinical reasoning neurologic pathways doctors must develop, and emphasizes the "zebra paradox"— rare diseases remain rare even when symptoms match the textbook. Dr. Dawn shares a personal case of a patient with throat shingles, leading her to use a medical AI (OpenEvidence) to investigate Shingrix risks. An Australian study found an elevenfold increase in shingles within 21 days of the first Shingrix dose in adults over 65, though dose two reduced overall risk by 73%. She explains this could be one of several things such as immune reconstitution inflammatory syndrome (IRIS), or that the AS01B vaccine adjuvant's strong activation may transiently reactivate latent virus, and recommends valacyclovir prophylaxis for high-risk patients for their first Shringrex shot.. Mira discusses AI in education, noting the shift from professors threatening plagiarism charges to teaching students how to critique AI output, emphasizing taking summaries "with a grain of salt." Dr. Dawn describes Chinese research scanning 1,154 children that identified a third ADHD subtype—severe emotional dysregulation—showing 45 abnormal brain regions versus 26 in the inattentive and hyperactive-impulsive types, with standard stimulants working poorly for this group. She connects this to traditional psychiatric personality disorder classifications and A discussion of vagus nerve stimulation's emerging applications for autoimmune conditions. Dr. Dawn and Mira discuss menstruation and bodily autonomy, then describe the Somedays period pain simulator that uses electrical impulses to let men experience menstrual cramps, highlighting differing pain thresholds. An emailer references a Radiolab episode about deliberate hookworm infection to treat asthma and allergies. Dr. Dawn explains parasites release immunosuppressants to survive, including anti-inflammatory protein-2 (AIP) now in drug development, which stimulates T-regulatory cells and IL-10 while "alarmins" inhibit lung inflammation—though this increases vulnerability to new infections. A caller with H. pylori and frequent viral infections asks whether S. boulardii and reuteri probiotics are safe given her low immunity. Dr. Dawn explains immunosuppression warnings target transplant-level drug suppression, not a tendency toward viruses like hers. Dr. Dawn thinks that her near-zero natural killer cells explain fr

Broadcast from KSQD, Santa Cruz on 5-14-2026: An emailer from Switzerland follows up on the case of neurological symptoms, warning about the fox tapeworm Echinococcus multilocularis from unwashed garden vegetables and tick-borne encephalitis requiring the FSME vaccine available in Europe. Dr. Dawn adds that cysticercosis from undercooked pork leaves calcified brain lesions detectable on CT scans. Dr. Dawn covers the Andes hantavirus outbreak that sickened at least eleven people on a cruise ship, with the virus spreading person-to-person unlike other hantaviruses. She explains that Andes virus grows to unusually high levels in blood and resists antimicrobial compounds in human saliva, with super-spreaders driving transmission chains. British paratroopers had to parachute medical supplies to an infected passenger on remote Tristan da Cunha island. Dr. Dawn reviews brain health supplements with UCLA longevity expert Gary Small. Both recommend curcumin (500-1,000mg) for anti-inflammatory effects and CoQ10 for statin users. She endorses multivitamins and high-quality fish oil but considers creatine, phosphatidylserine, and nicotinamide riboside insufficiently proven for cognitive enhancement. A caller asks about supplements and testosterone for a 77-year-old. Dr. Dawn recommends topical testosterone (patches, creams, gels) over injections to avoid testicular shrinkage and elevated sex hormone-binding globulin. She emphasizes protein intake matching one's age in grams, branched-chain amino acids during exercise, and warns against fasted training after age 65. An emailer shares news that PCOS is being renamed to polyendocrine metabolic ovarian syndrome (PMOS) because many patients lack ovarian cysts, and genetic males can also have the condition. Dr. Dawn explains it's fundamentally an endocrine and metabolic disorder involving insulin resistance, elevated testosterone, and DHEA dysregulation. A study found that infrasound—low-frequency sound below human hearing range—elevated cortisol and worsened mood in subjects who didn't know and couldn't detect it was playing. Old buildings generate infrasound through aging boilers, ventilation ducts, and metal pipes, potentially explaining why, beyond autosuggestion, that old "haunted" houses feel spooky.

Broadcast from KSQD, Santa Cruz on 5-07-2026: Dr. Dawn debunks the 1971 "220 minus age" maximum heart rate formula, noting a 2025 study found individual predictions were off by up to 20 beats per minute. She recommends the Tanaka equation (208 minus age) times 0.7, but emphasizes tracking improvement trends rather than absolute numbers. ConsumerLab testing found Safe Catch Wild Elite Pure Tuna and Wild Ahi Yellowfin Tuna had no detectable mercury, prompting Dr. Dawn to reconsider eating tuna after years of avoidance due to concerns about mercury bioaccumulation and its effects on nerve microtubules. A meta-analysis of 115 studies involving 55,000 men found limiting ejaculation before IVF leads to increased sperm DNA damage and poorer motility. Clinical trials showed 46% IVF pregnancy rates with less than 48 hours abstinence versus 36% with longer periods. A personalized mRNA vaccine for pancreatic cancer showed striking results: of 16 patients whose tumors were surgically removed, half produced killer T-cells targeting cancer, and seven of those eight remain alive six years later. Pfizer and Valneva's Lyme disease vaccine reduced infection by over 70% in a trial of 9,400 people ages five and up. Nearly half a million Americans contract Lyme annually, and chronic infection can cause nervous system damage and chronic fatigue. Dr. Dawn explores the gray-market peptide ecosystem, where compounds are sold as "research chemicals" with wink-and-nod marketing. A 2018 Belgian study found purity levels ranging from 5% to 99.9%, with some samples containing arsenic, lead, or industrial contaminants. A study of 450 people found that blocking smartphone internet access for two weeks improved sustained attention equivalent to reversing 10 years of age-related cognitive decline, with depression symptom improvements comparable to cognitive behavioral therapy. A multi-country study of 241 unresponsive patients found that 25% showed brain activity indicating consciousness when asked to imagine playing tennis during advanced brain scans. Scientists call this cognitive motor dissociation, and by some estimates tens of thousands of Americans may be misdiagnosed. Chinese researchers grew functional adrenal cortex organoids that responded to pituitary hormones and produced cortisol when transplanted into mice. They also introduced genetic mutations to create organoid models of Cushing's syndrome for drug testing. A Science paper identified the neural pathway connecting psychological stress to eczema flare-ups: sympathetic neurons from the stellate ganglion recruit eosinophils to the skin. Researchers traced the pathway using pseudo-rabies virus injected into skin. Mouse studies showed prenatal stress causes elevated corticosterone in amniotic fluid, which activates fetal mast cells derived from the yolk sac. Offspring develop eczema-like lesions in areas

Broadcast from KSQD, Santa Cruz on 4-30-2026:>/p> Dr. Dawn opens with a bike safety public service message, noting a 34% increase in bicycle use in Santa Cruz alongside rising e-bike accidents. She urges drivers to stay vigilant and calls for education and enforcement of helmet laws, particularly for riders under 18. A University of Michigan researcher discovered that standard nitrile, latex, and vinyl gloves shed stearate particles indistinguishable from polyethylene under spectroscopy, contaminating microplastics research with approximately 2,000 false positives per square millimeter. Only clean-room gloves avoided this problem, throwing years of microplastics studies into question. Dr. Dawn explains skin's three-layer structure and the stratum corneum's ceramide-based moisture barrier. She warns against stripping natural oils with astringents and hot showers, notes that UV disrupts proteins holding skin cells together, and cites a 2019 study showing moisturing treatment reduced circulating inflammatory cytokines in older adults. Making music coordinates sound, vision, motor control, and imagination across the brain. Studies show musicians have more gray matter, better executive function, sharper memory, and even reduced pain sensitivity. A 2010 paper found musicians who began before age seven have a larger corpus callosum, and a 2024 study showed pianists had better working memory while woodwind players did best at executive function. Stanford researcher Pascal Geldsetzer analyzed populations in Australia, New Zealand, Wales, and Ontario, finding the Shingrix vaccine reduces dementia risk by up to 20%. Dr. Dawn hypothesizes that even "dormant" varicella triggers low-level inflammation affecting brain microglia, and recommends spacing Shingrix three months apart from the second dose rather than one month to avoid side effects. A Nature study of 175 people watching movies found that observing someone being touched activates the same brain regions as being touched yourself—your brain experiences sensations in corresponding body parts. This vision-touch link could enable less invasive sensory testing for autistic individuals. Princeton and Flatiron Institute researchers identified four distinct autism phenotypes: broadly affected (10%), mixed with developmental delay (19%), moderate challenges (33%), and social/behavioral (37%). A second Nature study confirmed genetically distinct forms unfold on different timelines, with post-age-six diagnoses showing different genetic profiles than early childhood cases.

Broadcast from KSQD, Santa Cruz on 4-23-2026: Dr. Dawn highlights ARPA-H-funded breakthroughs: Duke researchers created injections enabling cartilage cells to divide and remodel bone, UC Boulder developed intermittent-burst delivery of a repurposed drug that reversed rabbit arthritis in 4-8 weeks, and Columbia printed a living 3D knee using stem cells on biodegradable scaffolding. She notes the agency's budget was cut by $945 million despite requiring human trials within 18 months of funding. A cord blood study across 200 countries links phthalates—found in food packaging, vinyl flooring, shampoos, and toys—to placental disruption and premature birth. Dr. Dawn warns that removing specific chemicals just leads to untested replacements, and urges avoiding microwaving in plastic. An emailer asks about microbiome and exercise motivation. Dr. Dawn describes research showing Veillonella atypica bacteria eat lactate produced during exercise and trigger dopamine production via the vagus nerve, creating a reward loop. Bred "super-runner" mice ran three times longer than average, but antibiotics reduced their running by 21%, implicating microbiome involvement. Dr. Dawn expands on cortisol dynamics: levels should rise gradually from 3 a.m., spike threefold at waking to synchronize hormones, then decline throughout the day. Chronic stress keeps cortisol elevated, while burnout from sustained overproduction eventually exhausts the adrenals and disrupts circadian rhythm, requiring 6-12 months to restore. An emailer asks about food-based detoxification for skin and inflammation. Dr. Dawn explains that plant bioflavonoids—originally insecticides—trigger enzyme production that also breaks down synthetic pollutants, with sulfur-containing vegetables (crucifers, onions, garlic) particularly important. Colorful fruits and vegetables scavenge free radicals that damage DNA and collagen. Dr. Dawn explores red and near-infrared light therapy (600-1100nm), which boosts ATP production by energizing cytochrome c oxidase in mitochondria. The FDA approved a device for dry macular degeneration, and red light is recommended for chemotherapy-induced oral mucositis. She notes modern buildings filter these wavelengths, potentially starving us of light our bodies evolved to need. Dr. Dawn shares research on unsupervised childhood play, citing psychologist Peter Gray's finding that independent play develops internal locus of control—the belief you can influence outcomes. such as youth anxiety and depression, as children no longer learn to self-soothe through tolerating boredom.

Broadcast from KSQD, Santa Cruz on 4-16-2026: Dr. Dawn opens with a follow-up from an email from Maryland about a friend in Switzerland, who has ongoing neurological and gastrointestinal symptoms. She reviews the earlier effort to connect him with functional-medicine resources in Switzerland, then focuses on a new observation that the patient may have had multiple parasitic infections during travel in Europe. Dawn agrees that this may have left a major gap in the workup and says that, in puzzling neurologic cases, a sleep-deprived EEG can sometimes reveal a “fingerprint” of brain-based dysfunction even if the patient is not actively having symptoms during the test. Dr. Dawn says that for people over 60 who have never had a heart attack or stroke, daily baby aspirin is no longer considered a good routine preventive measure because the bleeding risks, especially gastrointestinal bleeding, can outweigh the cardiovascular benefit. She makes the distinction that aspirin may still make sense for secondary prevention in people who already have established cardiovascular disease. She next reviews several medications that she thinks many older adults should reconsider. She explains that phenylephrine, which replaced easier access to pseudoephedrine in many cold remedies, has been found to work no better than placebo . She also says Colace is not very effective, and she strongly advises older adults to avoid Benadryl because it accumulates with age, increases fall risk, and may be associated with cognitive decline. She adds that beta blockers are no longer preferred first-line treatment for uncomplicated hypertension in many older patients, and that medications targeting the angiotensin pathway are generally favored instead. Dr. Dawn introduces Mira Achilles in the studio, describing her as her excellent administrative assistant. Mira explains that she gathered health questions from peers from her college world. Mira asks what best supports focus for someone with ADHD working at a desk job. Dr. Dawn says the two evidence-based pillars are cognitive behavioral therapy and exercise. She walks through practical strategies including using calendars, reminders, index cards, and to-do lists; sorting tasks by urgency and importance; breaking large projects into smaller steps; creating small reward loops by checking off progress; and deliberately reducing distractions in the work environment.. She emphasizes that movement and exercise improve attention and executive function, and that ADHD management often improves when sleep timing is stabilized. Another of Mira’s peers asks whether women should avoid very cold showers or ice baths during the luteal phase or around menstruation. Dr. Dawn says the answer is not absolute, but she cautions that cold exposure can hit women differently depending on hormonal state. She notes that the luteal phase may make vasoconstriction and cold sensitivity more pronounced

Broadcast from KSQD, Santa Cruz on 4-09-2026: Dr. Dawn shares a follow-up from an emailer in Switzerland providing seven functional medicine practitioner addresses near Zurich and Aargau, noting that Switzerland uses different terminology but is actually an "epicenter of functional medicine." Dr. Dawn calls for support of the bipartisan Break Up Big Medicine Act, modeled on Glass-Steagall, which would prohibit common ownership of medical providers with insurers, pharmacy benefit managers, or drug wholesalers. She explains how vertical integration by companies like UnitedHealth, CVS/Aetna, and Cigna allows them to game medical loss ratio requirements through self-dealing while driving up costs. A European clinical trial implanted 2mm x 2mm light sensors beneath the retinas of 38 people with advanced macular degeneration, with 80% gaining clinically meaningful improvement (two lines on the vision chart) after one year. The device bypasses damaged rods and cones, sending camera images from glasses directly to the optic nerve. Dr. Dawn explains that air temperature warnings are measured in shade, but direct sunlight can add 20°C to heat exposure. Heat stroke triggers gut permeability, releasing lipopolysaccharides that cause cytokine storms and organ failure. She advises fans over air conditioning when possible, shade, hydration, and loose natural-fabric clothing. An emailer asks if low-dose oral strontium supplementation has the same problem as pharmaceutical strontium. Dr. Dawn confirms it improves bone density scores without reducing fracture risk, and recommends telopeptide testing to monitor actual bone loss after discontinuing. An emailer's doctor wants to prescribe high-dose dexamethasone for low platelets. Dr. Dawn advises against rushing to steroids since platelets of 40 are adequate for clotting, recommending a hematology consultation and repeat testing with citrated blood. Dr. Dawn reviews fiber types: wheat dextrin (Benefiber) is fermentable but technically gluten-free; guar fiber (Sunfiber) ferments slowly and works for low-FODMAP diets; inulin feeds bifidobacteria and produces anti-inflammatory short-chain fatty acids; methylcellulose (Citrucel) is non-fermentable; and psyllium (Metamucil) is facing a class action lawsuit over undisclosed lead contamination. An emailer with varicose veins reports recurring superficial blood clots. Dr. Dawn explains these don't travel to lungs like deep vein clots, but repeated clotting suggests possible thrombophilia requiring workup. She recommends consulting a vascular surgeon about superficial venous ligation under local anesthesia. Analysis of 25,000 wearable users found that three daily "exercise snacks" of just 1-2 minutes of vigorous activity (stairs, running for a bus) reduced all-cause mortality by 38-40%. Benefits plateau around 7,500 steps daily, and simply standing up every couple of hours dramati

Broadcast from KSQD, Santa Cruz on 4-02-2026: Dr. Dawn briefly responds to an emailer in Aptos, advising that her numbers don't require rushing into therapy but recommending a more thorough workup. An emailer asks about her sister's osteoporosis treatment, including Reclast side effects and vitamin D levels of 28. Dr. Dawn recommends raising vitamin D to around 50, adding vitamin K2 (MK7-9) and calcium, and suggests weekly oral Fosamax as an alternative to annual Reclast infusions that cause week-long flu-like symptoms. A caller reports dizziness when sitting up in bed and recent fainting episodes during hot weather. Dr. Dawn distinguishes vestibular problems from postural hypotension — spinning dizziness when legs are still in bed suggests loose otoliths in the semicircular canals rather than blood pressure issues. She recommends the Dr. Foster vestibular exercises and increased fluid and salt intake. Cancer survival has reached a major milestone: 70% of U.S. patients now survive at least five years, up from 50% in the 1970s, thanks to reduced smoking and advances like immunotherapy and checkpoint inhibitors. An Estonian Biobank study of 67,000 adults found men's libido peaks in their early 40s while women's peaks in their 20s-30s with sharper decline around age 50, though testosterone levels begin falling in men's early 30s. Dr. Dawn frames perimenopause and menopause as natural transitions rather than diseases, explaining that perimenopausal hormone swings can actually be larger and more erratic than during fertile years. She recommends limiting caffeine (which is metabolized more slowly after menopause), alcohol, and spicy foods, and strongly advocates transdermal bioidentical hormones over oral synthetics—oral estrogen increases clotting risk 400% while transdermal carries no increased risk. An emailer asks about transcranial magnetic stimulation for depression. Dr. Dawn explains that while the technology works and shows benefit in studies, targeting remains challenging because each person's brain architecture differs based on individual developmental experiences. Researchers found that applying gamma-frequency electrical stimulation (40-90 Hz) to frontal and parietal lobes made participants more likely to choose generous money-splitting options with strangers, suggesting brain stimulation can nudge social decision-making toward altruism. A small Indian study found that daily conch shell blowing reduced sleep apnea symptoms by 34% after six months, similar to earlier didgeridoo research—blowing against resistance strengthens airway muscles and increases resting muscle tone during sleep.

Broadcast from KSQD, Santa Cruz on 3-26-2026: li> Dr. Dawn announces a UCSF study recruiting participants for psilocybin therapy to help patients cope with chronic low back pain, requiring ages 25-70 with failed prior treatments. A caller preparing for bladder stone surgery asks about avoiding a repeat of severe post-anesthesia disorientation. Dr. Dawn recommends pharmacogenomic testing through 3x4 Genetics to identify slow acetylator status and other detoxification enzyme variants that can guide anesthesiologists toward better drug choices. A clinical trial found that 24 minutes of music with binaural beats—where slightly offset audio in each ear generates synchronized brainwaves—significantly reduced anxiety in medicated patients. Dr. Dawn encourages trying this accessible, low-risk intervention. Chronic noise exposure triggers oxidative stress, inflammation, and endothelial dysfunction, increasing cardiovascular disease risk. Data centers and server farms are emerging noise pollution sources, and Dr. Dawn recommends affordable noise-canceling headphones as a health investment. A Crohn's patient in Switzerland reports alarming neurological symptoms including speech arrest with preserved awareness and transient visual disturbances. He is having trouble finding any Functional Medicine trained physician and Dr. Dawn recommends emailing to [email protected]. Furthermore, Dr. Dawn suspects possible seizure activity from brain inflammation and recommends pursuing a sleep-deprived EEG and MRI through a neurology referral. MIT researchers discovered Interlectin-2, a protein that both strengthens the mucus barrier by cross-linking mucins and directly traps and kills pathogens like Salmonella and Shigella. Imbalanced levels may contribute to inflammatory bowel disease. Synthetic versions may be an effective treatment for inflammatory bowel disease. A 33-year-old man survived 48 hours without lungs after flu-triggered bacterial pneumonia caused ARDS and multiple organ failure. Surgeons removed both lungs treat septic shock while ECMO (extracorporeal oxygenation)sustained him until a successful double lung transplant. A meta-analysis of 43 studies involving millions of births found no evidence that acetaminophen use during pregnancy increases autism, ADHD, or intellectual disability risk, contradicting recent political claims. Green tea contains about 30% more L-theanine than black tea, with studies showing 200mg daily improves verbal fluency, sleep quality, and reduces anxiety. Decaffeinated green tea retains full theanine content. Pop star Robbie Williams developed scurvy while on GLP-1 weight loss drugs, highlighting that only 2 of 40+ major GLP-1 trials assessed vitamin intake. Dr. Dawn urges anyone on these medications to take a comprehensive multivitamin.

Broadcast from KSQD, Santa Cruz on 3-19-2026: Dr. Dawn warns that stacking multiple gummy supplements can cause GI distress from sugar alcohols like xylitol, sorbitol, and mannitol, with symptoms persisting up to three days after stopping. She recommends limiting sugar alcohol intake to 6mg daily and switching to non-gummy formulations if experiencing bloating, cramping, or diarrhea. An emailer asks about finding treatment for abdominophrenic dyssynergia, a condition causing progressive abdominal distension after meals. Dr. Dawn recommends using AI search to locate physical therapy centers offering EMG-guided biofeedback, and suggests ruling out SIBO and low stomach acid. Researchers at the American Chemical Society have created modified psilocybin variants designed to release the active compound more slowly, potentially reducing hallucinogenic effects while maintaining therapeutic benefits. Dr. Dawn expresses concern that such patentable alternatives could prevent legalization of natural psilocybin for addiction treatment. Japanese researchers used PET imaging to discover that ketamine rapidly relieves treatment-resistant depression by altering the distribution of AMPAR glutamate receptors in the brain. Within two weeks, patients' receptor patterns normalized to resemble healthy controls, with enduring changes tracking symptom improvement. A study found CBD and CBG improved fatty liver disease markers in mice by increasing phosphocreatine energy reserves and reactivating cellular recycling centers. Dr. Dawn notes the compounds were injected directly into the abdominal cavity, making the results impossible to translate to oral consumption, an example of headlines exceeding reality. King's College London research found that root canal treatment for apical periodontitis improved blood sugar, cholesterol, and inflammation markers over two years. Dr. Dawn advises regular flossing and periodically tapping teeth with a metal instrument to detect painful teeth needing attention. An emailer asks about Crohn's disease and the gut-brain axis. Dr. Dawn explains that the vagus nerve serves as a bidirectional highway between brain and gut, with gut bacteria producing serotonin that affects mood, while stress increases intestinal permeability and worsens inflammation. In medical news of the weird, scientists discovered that malaria parasites contain tiny iron crystals powered by hydrogen peroxide—the same fuel used in rockets. This first-ever biological self-propelled nanoparticle could inspire new approaches to powering medical nanobots.

Broadcast from KSQD, Santa Cruz on 3-12-2026: Dr. Dawn discusses Michael Pollan's critique of MAHA dietary recommendations, agreeing that ultra-processed foods should be avoided but noting the lack of science supporting high saturated fat intake. She acknowledges extra virgin coconut oil as an exception that doesn't raise LDL, and pushes back on the social Darwinism embedded in anti-vaccine, anti-welfare MAHA thinking. Dr. Dawn expresses serious concern about Surgeon General nominee Casey Means, a Stanford-trained physician who dropped out of residency to become a wellness influencer. She objects to Means hawking supplements and glucose monitors for personal profit—conduct she considers unethical for a physician giving medical advice. An emailer from Switzerland shares success managing histamine intolerance by avoiding aged meats, shellfish, fermented foods, and cross-reactive pollens during hay fever season. The game-changer was taking DAO (diamine oxidase) supplements before meals to break down histamine in the gut. Researchers found that blood from pediatricians who worked in children's hospitals for over a decade contains powerful antibodies against RSV—up to 25% more effective than existing treatments—built up through years of constant exposure. Dr. Dawn critiques a study finding 2.5 times more microplastics in prostate tumor tissue than surrounding healthy tissue, noting that fast-growing cancers develop extra blood vessels and would naturally incorporate more circulating plastics. She attributes the 6% rise in late-stage prostate cancer to discontinued PSA screening rather than microplastics. An emailer asks what to do about microplastics already in our bodies. Dr. Dawn says there's no way to remove them, and advises avoiding microwaving in plastic, limiting breaded processed foods, and rinsing well after brushing teeth with plastic bristles. AI analysis of mammograms can now detect breast artery calcification as a marker for cardiovascular disease risk, with severe calcification indicating 3.3 times greater risk of heart attack, stroke, or death. This could identify high-risk women years before cardiac events. Dr. Dawn questions a non-peer-reviewed study presented at an orthopedic meeting found five years of GLP-1 drug use associated with 30% higher osteoporosis risk, 150% higher osteomalacia risk, and increased tendon ruptures—likely from reduced food intake and vitamin D consumption. Twin studies now estimate genetics account for 55% of lifespan variation when separating internal biological causes from external factors. Separately, fathers who showed warmth and responsiveness to 10-month-old babies had children with lower inflammation and better blood sugar regulation at age 7—an effect not seen with mothers' parenting. Grandparents actively involved in childcare showed slower cognitive decline than non-caregiving grandparents. Dan

Broadcast from KSQD, Santa Cruz on 3-05-2026: Dr. Dawn demonstrates how to critically read a science paper using a widely-publicized study claiming adolescent cannabis use causes psychotic, bipolar, and anxiety disorders. She identifies multiple methodological problems: only 5.7% of Kaiser adolescents admitted cannabis use versus 11.2% in anonymous national surveys, suggesting massive underreporting; the study conflates any use with heavy use; and with 463,000 participants, trivially small differences become statistically significant but clinically meaningless. She proposes reverse causation—that prodromal schizophrenia symptoms may drive teens to self-medicate with cannabis rather than cannabis causing psychosis. The study also included "disruptive behavior disorder" diagnoses that lack rigorous criteria, and she notes diagnostic codes are sometimes chosen for insurance reimbursement rather than accuracy. While acknowledging high-dose THC before age 16 may affect brain development, she concludes the headlines claiming causation are not supported by the actual findings. Dr. Dawn discusses how aquaculture—now producing 60% of fish consumed globally—has become a breeding ground for antibiotic-resistant pathogens. More antibiotics per kilogram are used in fish farming than in any other animal agriculture, with drugs dissolving into water and sediment where bacteria develop resistance. One study found antibiotic-resistant bacteria in over 80% of shrimp species tested across multiple countries. Through horizontal gene transfer, these resistance genes spread to human pathogens—a 1991 Latin American cholera outbreak affecting nearly a million people may have acquired drug resistance from Ecuadorian shrimp farms. Dr. Dawn reports that the FDA rejected Moderna's mRNA flu vaccine application without even reviewing it, despite trials of 41,000 people showing it was 27% more effective at preventing illness and 29% more effective at preventing hospitalization than existing vaccines. She attributes this to politicized anti-mRNA bias lacking scientific basis, noting that venture capital investors like Blackstone (who invested $750 million) will now avoid vaccine development, effectively handing this critical technology to other countries. Dr. Dawn describes the "wellness industrial complex"—pharmaceuticals, tech, testing companies, and health influencers creating content that pathologizes normal behaviors. YouTube health videos have amassed 200 billion views, and 30% of British respondents now get medical advice from AI chatbots. She cites a 400% increase in British adults seeking ADHD diagnoses, noting that analysis of top TikTok ADHD videos found less than 50% accurately reflected actual symptoms. Many influencers receive undisclosed payments to mention products, and the U.S. and New Zealand are the only countries allowing direct-to-consumer drug advertising. A caller asks about navigating Medicare afte

Broadcast from KSQD, Santa Cruz on 2-26-2026: Dr. Dawn opens with an urgent measles advisory, noting the virus has an R-value of 15 compared to COVID's peak of 5, with South Carolina reporting over 1,000 cases. She recommends those who received only one MMR shot—particularly people now in their 60s—get an immune titer blood test, as protection declines after 40-50 years. Measles can cause "immune amnesia" destroying immunity to other pathogens, and rarely leads to fatal subacute sclerosing panencephalitis years later. Dr. Dawn criticizes Quest Labs' cholesterol reporting, which flags average levels as "moderate risk" with alarming red H markers even when values fall within their own stated normal ranges. She explains this creates unnecessary panic and pushes patients toward statins based on outdated 2008-2012 guidelines, when cardiology has since recognized that cholesterol can be too low. An emailer asks how an EKG can detect a past heart attack from "jagged lines." Dr. Dawn explains that each spike represents electrical signals moving toward or away from electrode pads, and a 12-lead EKG views the heart from multiple angles—smaller-than-expected spikes in specific leads indicate dead or damaged heart muscle. She urges everyone to learn CPR and AED use, which more than doubles survival chances. An emailer reports that food tastes strong on the first bite but becomes tasteless thereafter. Dr. Dawn identifies numerous medications causing taste changes including calcium channel blockers, beta blockers, statins, diuretics, and even acetaminophen. She also highlights zinc—both deficiency and toxicity above 40mg daily can impair taste, noting a zinc nasal spray was pulled from market after causing smell loss. An emailer asks about Prenuvo full-body MRI scans costing $499-1,000. Dr. Dawn cautions that while Prenuvo found 22 cancers in 1,000 people scanned, 1 in 20 scans requires follow-up biopsy and more than half are false positives—leading to stress, expense, and potential complications from unnecessary procedures. An emailer asks about seed oils after reading a Johns Hopkins article defending them. Dr. Dawn distinguishes fruit oils (olive, avocado) from industrially-extracted seed oils requiring hexane solvent, a neurotoxin that may leave residues despite claims of evaporation. She cites a BMJ study showing coconut oil raised HDL (good cholesterol) while matching olive oil's LDL impact, and recommends cold-pressed oils while avoiding hexane-extracted products, especially for infants.

Broadcast from KSQD on 5-30-2024 and replayed on 2-12-2026: Cognitive errors in medicine dismissing unusual presentations as psychological. A case of Pediatric Autoimmune Neuropsychiatric disorders Associated with Streptococcal Infections (PANDAS). Anti-NMDA receptor encephalitis causing psychiatric symptoms. Failures of genetic research to identify causes. The Need for integrating neurology and psychiatry; Importance of testing for antibodies and using MRI scans. Detailed explanation of immune tolerance, peripheral tolerance, and the phenomenon of molecular mimicry in diseases like multiple sclerosis and celiac disease. Importance of addressing root causes rather than just symptoms. Historical context and current advancements in treating autoimmune diseases like type 1 diabetes, lupus, and multiple sclerosis using reprogrammed immune cells and iron oxide nanoparticles. Explanation of how the liver filters blood and helps establish immune tolerance by processing cellular debris and antigens. Advances in engineering regulatory T cells to target specific disease sites and calm inflammatory responses. Exploration of new diagnostic tools and the potential of AI in understanding complex psychiatric conditions.

Broadcast from KSQD, Santa Cruz on 3-05-2026: >ul> Dr. Dawn presents a whimsical "theme park tour" of the upper gastrointestinal tract, from saliva production triggered by sight and smell of food, through the esophageal sphincter's iris-like opening, into the stomach's pH-1 acid bath where parietal cells produce 3,000 mg of hydrochloric acid per meal. She explains protective mechanisms including the bicarbonate layer beneath stomach mucus, H. pylori's role in ulcers, and how H2 blockers and proton pump inhibitors work—cautioning about long-term PPI effects on B12 and calcium absorption. The tour continues through the pylorus into the duodenum where pancreatic enzymes and bile converge, then along the 23-foot small intestine with its tennis-court surface area of villi absorbing nutrients, iron in the duodenum, most nutrients in the jejunum, and B12 requiring intrinsic factor in the ileum. Dr. Dawn explains why pancreatic cancer—projected to become the second leading cause of cancer death by 2030—is so deadly, using a medieval castle metaphor. The tumor microenvironment acts as an impenetrable moat of desmoplastic stroma made of fibroblasts, collagen, and hyaluronic acid that blocks drugs and immune cells. Over 90% of cases have K-RAS mutations acting as growth accelerators that also thicken this protective barrier and increase CD47 "don't eat me" signals. She discusses emerging treatments including K-RAS inhibitors, PARP inhibitors for BRCA mutations, and combination immunotherapies showing 67% response rates, while noting that CAR T-cell therapy and checkpoint inhibitors alone fail because they cannot penetrate the stroma. Dr. Dawn summarizes Duke researcher Herman Ponzer's work using doubly-labeled water to measure total energy expenditure, revealing that humans burn 20-60% more calories than other great apes when adjusted for body mass. His surprising finding: Hadza hunter-gatherers walking 8-14 kilometers daily burn the same calories as sedentary Americans—the body compensates by reducing energy spent on inflammation and stress responses. This "constrained energy expenditure" model explains why exercise alone doesn't cause weight loss, though it remains crucial for preventing weight gain, reducing disease risk, and potentially tamping down harmful stress responses.

Broadcast from KSQD, Santa Cruz on 1-29-2026: An emailer asks about hemorrhoids affecting 2 relatives,a 60-year-old man and his 20-year-old daughter, with the daughter also experiencing constipation worsened by fiber supplements. Dr. Dawn explains hemorrhoids are essentially varicose veins of the anus, with 102 genetic regions identified affecting blood vessel and smooth muscle strength. She emphasizes that fiber supplements without adequate water create "cement in the pipe"—recommending 16-24 ounces of water with supplements and 2 liters of clear water daily. Miralax also requires sufficient hydration to work. Key strategies include exercise to stimulate gut motility, staying off the toilet if unable to produce results, using a standing desk to reduce prolonged sitting pressure, and triggering the gastrocolic reflex by eating. Dr. Dawn discusses research on the "volatilome"—volatile organic compounds in breath that reflect gut microbiome composition. Researchers using sterile mice colonized with specific bacteria could identify bacterial fingerprints through breath analysis. The technique identified disease-associated compounds for tuberculosis and malaria, and correlated specific gut bacteria with asthma severity in children. The research suggests breath testing could eventually replace stool samples for microbiome assessment and disease screening. She explains detoxification biochemistry, distinguishing between water-soluble toxins easily filtered by kidneys and fat-soluble toxins requiring liver transformation. Phase one converts fat-soluble molecules into reactive intermediates—dangerous if they linger—while phase two attaches water-soluble molecules like glutathione to neutralize them for excretion. Supporting phase two requires green tea, cruciferous vegetables, garlic, and curcumin. She cautions against extended fasting for detox, especially over age 50, as it depletes the body's detoxification resources and muscle mass. A caller asks about alkaline versus acidic water. Dr. Dawn explains you cannot alkalinize blood since kidneys maintain pH, but alkaline urine is beneficial. Rather than expensive alkaline waters, adding a pinch of baking soda achieves the same effect. Eating a 3:1 ratio of fruits, vegetables, and grains to animal products naturally alkalinizes urine. She notes lemons paradoxically alkalinize because kidneys overcompensate for the acid load. A caller asks about managing heart disease after receiving a third stent. Dr. Dawn recommends the Mediterranean diet over DASH for cardiac patients, as Mediterranean emphasizes fish, whole grains, and fiber that binds cholesterol for excretion, while DASH focuses on calcium for hypertension. She encourages exploring exercise options through meetup.com groups and the hospital's lifestyle center, emphasizing that consistent effort can reduce biological age by 3-5 years regardless of chronological age.

Broadcast from KSQD, Santa Cruz on 1-22-2026: An emailer from Canada asks about long-term Remicade (infliximab) use for her 16-year-old daughter's ulcerative colitis. Dr. Dawn explains the drug blocks tumor necrosis factor, which stops autoimmune attacks but also weakens infection defense—increasing risk of fungal infections, tuberculosis, and after about 10 years, slightly elevated blood cancer risk. She recommends the daughter practice good hygiene and mask in high-risk settings. For achieving full remission, she suggests vitamin D levels around 75-80, DHEA supplementation, strict gluten avoidance due to its pro-inflammatory effects, and working with a certified functional medicine practitioner to heal the gut and potentially withdraw medication. Dr. Dawn presents a case study of a 27-year-old woman with progressive weakness, pins-and-needles sensations, and impaired balance. Despite normal B12 blood levels, elevated homocysteine and methylmalonic acid revealed functional B12 deficiency from using 20-30 nitrous oxide whippets daily. Nitrous oxide oxidizes the cobalt atom in methylcobalamin, permanently inactivating the enzyme needed for myelin sheath maintenance. Treatment requires months of daily B12 injections with recovery taking up to 84 weeks. She warns that nitrous oxide also interacts dangerously with Viagra-type drugs (causing dangerous blood pressure drops), methotrexate, stimulants, hallucinogens, and respiratory depressants. She describes Canadian researchers developing a miniaturized 3D printer for vocal cord repair. After removing nodules that cause hoarseness, the device prints hydrogel along the wound to create a flat surface preventing keloid-like regrowth, rather like spackling a wall before healing occurs underneath. Dr. Dawn discusses lipoprotein(a), written as Lap(a), a genetic cardiovascular risk factor discovered in the 1960s. This relative of LDL carries a protein that promotes blood clots, thus raising heart attack and stroke risks. In a recent large survey, only about 14% of people have been screened despite its significance. New drugs like pelicarsin can reduce Lp(a) levels up to 80%,trials underway to confirm a benefit of reduced cardiac events. She notes tennis star Arthur Ashe had high Lp(a) contributing to his coagulopathy. A natural option is already available. She recommends lumbrokinase, derived from earthworms and used in traditional Chinese medicine, as an existing treatment that combats high Lp(a) and counteracts its procoagulant effects. The product Boluoke is commercially available, offering an alternative to high-dose niacin which causes intolerable flushing and diarrhea. Dr. Dawn reports research finding people with anxiety disorders have 8% lower choline levels in brain regions regulating emotion. Increasing choline could help. Choline sources include eggs (two eggs provide 300mg of the 500mg daily choline need), organ meats, salmon, soybeans, and

Broadcast from KSQD, Santa Cruz on 1-15-2026: An emailer from Switzerland asks about fluorescein angiography requested before her first retina appointment. Dr. Dawn suspects protocol-based medicine screening for macular degeneration and suggests negotiating to see the doctor first given her different reason for seeing a retinal specialist. She encourages patients to maintain agency in medical settings. An emailer asks about creatine supplements. Dr. Dawn notes it helps muscle development in people doing weight training at 3-5 grams daily, but does nothing for aerobic-only exercisers. Claims about cognition and mood lack solid research. She advises against high-dose "loading," and cautions that creatine causes fluid retention problematic for congestive heart failure and should be avoided with stage 3 or higher kidney disease. Dr. Dawn reminds listeners it's not too late for flu shots, noting this season's H3N2 strain emerged after vaccine formulation was finalized. She laments mRNA vaccine research defunding, as that technology allows rapid reformulation. She describes organoids—tissues grown from stem cells that self-organize into primitive organ structures, enabling rapid drug screening without animal testing. Stanford researchers created assembloids by placing four neurological organoids together that spontaneously connected and built the ascending sensory pain pathway, offering new approaches to studying chronic pain. Dr. Dawn explains research showing satellite glial cells transfer healthy mitochondria to spinal sensory neurons through tunneling nanotubules. When this transfer fails, neurons fire erratically causing pain. Infusing healthy mitochondria into mouse spinal columns cured peripheral neuropathy—suggesting future periodic infusion treatments for humans. She reports Texas A&M researchers created "nanoflowers" from molybdenum disulfate that double stem cell's mitochondrial production, potentially supercharging regenerative medicine for conditions including Alzheimer's and muscular dystrophy. A caller asks about flu vaccines with egg allergy. Dr. Dawn explains that his gastrointestinal reactions to eggs differ from dangerous IgE allergies causing hives or anaphylaxis—GI intolerance doesn't preclude vaccination. Dr. Dawn reveals that 20 years of Parkinson's research followed a false lead. MRI showed increased iron in patients' brains, prompting iron chelation trials—which worsened symptoms. The problem: MRI detects paramagnetic ferric iron (stored, inert) not ferrous iron (biologically active). Patients accumulate useless ferric iron but are deficient in usable ferrous iron. Earlier 1980s studies showing that iron supplementation helped were ignored and abandoned prematurely. She suggests Parkinson's patients discuss iron supplementation with neurologists. She will post the link in the resources page on her website. A caller concerned about e

Broadcast from KSQD, Santa Cruz on 1-08-2026: Dr. Dawn concludes her 2025 medical advances recap, noting that while GLP-1 weight loss drugs showed unexpected benefits for addiction, schizophrenia, and dementia risk, Novo Nordisk recently reported semaglutide had no effect on cognition in people with existing dementia or mild cognitive impairment. She describes the first successful human bladder transplant performed on May 4th. The 41-year-old recipient received both kidney and bladder due to the bladder's complex blood vessel network. Surgeons practiced on cadavers with active circulation before achieving success, opening pathways for future bladder-only transplants for the 84,000 Americans diagnosed with bladder cancer annually. An emailer follows up about purslane for cognitive health. Dr. Dawn reviewed the referenced studies and found neither actually supported claims about purslane and cognition—one discussed the Lyon Heart Study's Mediterranean diet, the other described antioxidant properties. She cautions listeners that websites citing "scientifically proven" claims often reference articles that don't support their assertions. An emailer asks about statin alternatives after developing severe muscle pain on both atorvastatin and rosuvastatin. Dr. Dawn suggests he shouldn't be on statins given his classic adverse reaction. She recommends ezetimibe plus oat bran for cholesterol, metformin for his elevated triglycerides indicating insulin resistance, and checking LDL particle size and inflammation markers. She emphasizes that cholesterol is a risk factor, not a disease, and treating 50 low-risk people for 10 years prevents only one heart attack. A caller discusses plaque formation theory, comparing it to calluses. Dr. Dawn explains Linus Pauling's similar hypothesis that plaque forms at vessel bifurcations to protect against turbulent blood flow damage. She warns against driving total cholesterol below 130, as it disrupts steroid hormone production. The caller shares his mother's near-fatal rhabdomyolysis from statins—muscle breakdown releasing myoglobin that clogs kidneys—and criticizes data transfer failures between hospital systems. An emailer reports four UTIs in two months at age 79. Dr. Dawn questions whether all were true infections, since vaginal contamination causes false positives on dipstick tests. For confirmed UTIs, she recommends D-mannose and cranberry to prevent bacterial adhesion, post-void residual ultrasound to check for incomplete emptying, lactobacillus probiotics, and vaginal DHEA (Intrarosa) to restore mucosal thickness and disease resistance. Dr. Dawn describes Stanford's Phase III trial for dystrophic epidermolysis bullosa, where defective collagen-7 causes skin layers to separate at the slightest touch. Researchers take patient skin biopsies, use retroviruses to insert corrected genes, grow credit-card-sized skin grafts over 25 days, then sutur

Broadcast from KSQD, Santa Cruz on 1-01-2025: An emailer asks about omega-3 supplementation for memory at age 72. Dr. Dawn advises checking that fish oil capsules contain adequate DHA—at least 1,000 mg—since many omega-3 products have low DHA levels. She notes Medicare covers the same testing at standard labs as proprietary labs like OmegaQuant that charge patients directly. Beyond omega-3s, she emphasizes glucose control (hemoglobin A1c below 5.6) since the enzyme that breaks down insulin also clears beta-amyloid, and weight training to raise brain-derived neurotrophic factor (BDNF), which promotes new synapse formation essential for memory. Dr. Dawn reviews Popular Science's top 2025 health innovation: eye drops from Lens Therapeutics containing aceclidine that correct age-related farsightedness for 10 hours. The drops shrink the pupil to increase depth of field, improving near vision by three or more lines on eye charts within 30 minutes without affecting distance vision. Side effects include eye irritation, dimmed night vision, and headache. She describes Duke University's breakthrough allowing heart transplants from circulatory death donors using an on-table reanimation technique. This could expand the pediatric donor pool by 20%—critical since up to 20% of children die waiting for transplants. Dr. Dawn celebrates CAR-T immunotherapy for multiple myeloma, which saved her husband's life. Of 97 heavily pretreated patients, 38% achieved complete remission still present at five years, with over 50% total survival. The therapy removes T-cells, uses CRISPR to add receptors targeting cancer cell antigens, then reinfuses the modified cells. She highlights a UC Davis study showing remote blood pressure monitoring with home technology, education, and coaching dropped patients' average blood pressure from 150/80 to 125/74 in months—low-tech with high impact. Dr. Dawn explains the Nano Knife for prostate cancer, which uses localized electrical pulses delivered through thin wires to destroy tumors while sparing surrounding nerves. This minimally invasive approach could reduce erectile dysfunction and incontinence common with traditional surgery. She describes Gilead's Sunlenca, a twice-yearly injection for HIV prevention that's 99% effective. At $14,000 per injection in the US, proceeds help fund access in resource-limited countries where it can be distributed like a vaccination. Dr. Dawn discusses Journavx (suzetrigine), a new non-opioid pain medication working on sodium channels to block pain signals before reaching the brain. At $30 for 50 pills on GoodRx, it offers an alternative for surgical pain in patients with addiction history or genetic vulnerability to opioid dependence. She details the landmark case of Baby KJ, the first person to receive personalized CRISPR gene therapy. Born with a CPS1 enzyme deficiency causing toxic ammonia buildup, KJ was too

Broadcast from KSQD, Santa Cruz on 12-18-2025: Dr. Dawn opens by examining how market competition is actually working in the weight loss drug sector. Novo Nordisk's Ozempic and Wegovy compete against Eli Lilly's Monjaro and ZepBound, with prices dropping nearly 50% as companies launch direct-to-consumer websites. The main barriers remain needles and refrigeration, driving development of oral versions. Novo's Wegovy pill awaits FDA approval for early 2026 launch at $150 monthly. Next-generation drugs show remarkable results: Eli's retatrutide causes 24% weight loss in 48 weeks, while Novo's Cagrisema combines semaglutide with amylin to reduce muscle loss. Pfizer paid $10 billion for Metsera's once-monthly drug despite significant side effects. A quick fiber tip suggests adding plain psyllium to morning coffee for cardiovascular and microbiome benefits. Start with half a teaspoon and work up to two teaspoons (10 grams) over several weeks to avoid gas. The prebiotic fiber improves glucose tolerance and may reduce cancer risk. UC San Diego scientists discovered why cancers mutate so rapidly despite being eukaryotic cells with protected chromosomes. The answer is chromothripsis, a catastrophic event where the enzyme N4BP2 literally explodes chromosomes into fragments. These reassemble incorrectly, generating dozens to hundreds of mutations simultaneously and creating circular DNA fragments carrying cancer-promoting genes. One in four cancers show evidence of this mechanism, with all osteosarcomas and many brain cancers displaying it. This explains why the most aggressive cancers resist treatment. Research from 2013 shows any glucocorticoid use significantly increases venous thromboembolism risk, with threefold increases during the first month of use. The risk applies to new and recurrent clots, affecting both oral and inhaled steroids, though IV poses highest risk and topical the lowest. Joint injections fall somewhere between inhaled and oral. Anyone with prior blood clots should avoid steroids except for life-threatening situations like severe asthma attacks requiring ventilation. A meta-analysis of 20 randomized controlled trials shows creatine supplementation helps older adults (48-84) maintain muscle mass when combined with weight training two to three times weekly. The supplement provides no benefit without exercise. Recommended dosing starts at 2 grams and works up to 5 grams daily. Vegans benefit most since they consume little meat or fish. Important caveat: creatine throws off standard kidney function tests (creatinine), so users should request cystatin C testing instead for accurate renal health assessment. A new JAMA study suggesting risk-based mammogram screening is fatally flawed. First, researchers offered chemopreventative drugs like tamoxifen only to the high-risk group, contaminating the study design. Second, the demographics skewed heavily toward white college-educated

Broadcast from KSQD, Santa Cruz on 12-11-2025: Dr. Dawn presents colleague Dr. Paul Godin's essay on why US healthcare fails as a market system . She explains that healthcare violates every assumption of functional markets: patients can't compare options during emergencies, information asymmetry prevents informed decisions, demand is inelastic when one has an urgent medical issue, and trust is essential to medicine and in direct conflict with profit incentives. Since 1988's Knox-Keen Act allowed for-profit healthcare, private equity has acquired and stripped hospitals, while administrative costs consume enormous resources fighting over payments rather than providing care. She contrasts this with European models like Switzerland and Germany where everyone must participate, insurers must accept all patients, and profit on basic coverage is limited. She celebrates a vaccination success story: HPV vaccines have reduced cervical cancer by 50% over 30 years. The American Cancer Society now endorses self-collected vaginal samples for HPV screening, with an FDA-approved at-home kit from Teal Health allowing women to skip speculums and traditional Pap smears. Current guidelines recommend screening starting at age 25, with testing every five years after a negative result. Dr. Dawn issues a health alert about multiple hospitalizations in Santa Cruz County from foraged wild mushrooms identified incorrectly by phone apps. She describes cholinergic toxicity symptoms: sweating, excessive salivation, pinpoint pupils, and abdominal cramping—signs requiring immediate emergency care rather than waiting it out. She offers follow-up vaccine advice: "go in wet, then sweat." Hydrate before vaccination, then take a hot Epsom salt bath until sweat runs off your face. This helps eliminate adjuvants that cause post-vaccine fatigue and aches, which are often misinterpreted as catching illness from the vaccine itself. Dr. Dawn expresses alarm that Kennedy's reconstituted ACIP nearly voted to eliminate hepatitis B vaccination at birth. She notes infants exposed to infected mothers have 99% infection rates, with half becoming chronically infected and half of those developing terminal cirrhosis or cancer. Testing pregnant women misses infections acquired during pregnancy, and 12-16% of delivering women have no test records. Major insurers have committed to covering birth vaccination through 2026 despite the panel's actions. She offers holiday microbiome advice from researcher Karen Corbin: increase fiber intake through steel-cut oats, whole grain breads like Dave's Killer Bread, beans, apples, and alternative pastas made from lentils or garbanzo beans. Cooking potatoes ahead and reheating creates resistant starch that feeds beneficial gut bacteria, reduces inflammation, and even stimulates natural GLP-1 production. Dr. Dawn reviews research proving health insurance saves lives. When the ACA's Medicaid e

Broadcast from KSQD, Santa Cruz on 12-04-2025: Dr. Dawn opens with an experimental vaccine that prevents severe allergic reactions by targeting IgE antibodies. The vaccine could eventually replace current monoclonal antibody treatments like omalizumab that require injections every two weeks. She explains how adjuvants work in vaccines as additives that irritate the immune system enough to notice the vaccine target. Aluminum hydroxide is s common adjuvant. Modern vaccines use small pathogen fragments rather than whole organisms, requiring adjuvants to trigger adequate immune response. Dr. Dawn expresses concern about the US Advisory Committee on Immunization Practices reviewing aluminum adjuvants this week. A Danish study of over one million children finding no connection between aluminum with autism and ADHA contradicts RFK,Jr's public claims.She worries that removing aluminum could devastate vaccine effectiveness and children's health, noting that whenever vaccination rates drop, diseases like measles return to native circulation. She recounts pertussis vaccine history—when Japan stopped vaccination due to rare adverse reactions (approximately one death per million doses), they lost about 5,000 children to whooping cough in the first year. The newer acellular vaccine using pathogen fragments plus adjuvants is safer but only lasts 4-5 years versus lifetime immunity from the older whole-cell version, necessitating "cocooning" strategies where everyone contacting newborns must be recently vaccinated. Dr. Dawn describes a vaccine to prevent fentanyl from reaching the brain now starting clinical trials in the Netherlands. It pairs a fentanyl-like molecule with a carrier protein large enough to trigger antibody production. Once primed, the immune system attacks any fentanyl entering the blood, preventing highs and overdoses—potentially helping people in addiction recovery and those accidentally exposed through contaminated drugs. She reports the first documented death from alpha-gal syndrome. Alpha-gal is a meat allergy triggered by Lone Star tick bites; the tick essentially vaccinates humans against the alpha-galactosidase protein found on beef and pork. Cases have increased since 2010 as climate change expands the tick's range northward, yet a 2023 survey found 42% of doctors had never heard of the condition. Dr. Dawn highlights research from Edith Cowan University showing that blood drawn after exercise suppresses cancer cell growth when added to tumor cultures. In breast cancer survivors, plasma from high-intensity interval training or weight lifting caused cancer cells to stop growing or die; blood drawn before exercise had no effect. The key mechanism involves myokines, particularly IL-6, released by contracting muscles. A Stanford study found colon cancer survivors who exercised were 37% less likely to experience recurrence. A caller asks about pig-to-human heart trans

Broadcast from KSQD, Santa Cruz on 11-20-2025: Dr. Dawn discusses GLP-1 inhibitors like Zepbound and semaglutide showing unexpected benefits for addiction treatment beyond diabetes and weight loss. Patients in rehab report these drugs mute cravings for alcohol, cocaine, and cigarettes. Multiple studies show reduced substance abuse rates in users, with VA and NIH conducting trials examining brain activity and responses to triggers. With 80,000 annual drug overdose deaths and 48 million Americans having substance abuse disorders, these medications may revolutionize addiction treatment by dampening brain reward circuitry, though costs threaten healthcare budgets. A Stanford twin study found those twins assigned a vegan diet had substantially lower cholesterol, insulin, and body weight compared to their omnivore twins after several months, with LDL dropping 15mg, four pounds more weight loss, and 20% lower insulin. Dr. Dawn explains how a fungal disease decimating Central American frog populations caused 500% malaria increases in some areas. The fungus kills frogs by blocking skin electrolytes until hearts stop, eliminating tadpoles that eat mosquito larvae. Ecosystem collapses followed with algae blooms and snake population drops. She provides other examples showing how species losses affect human health, emphasizing the "one health" movement recognizing ecosystem health as fundamental to human wellbeing. An Australian study found people aged 70+ who listen to or play music regularly had 39% lower dementia rates, though causation remains uncertain. Princeton research shows music activates multiple brain regions simultaneously. Learning instruments increases gray matter, and musical memory remains intact in advanced dementia since it's stored separately from other memories. A caller discusses how modern screen-based activities provide less multisensory engagement than past social experiences like dances. Another caller describes Grover's disease causing persistent itchy skin with no known cause. Dr. Dawn recommends an elimination diet removing common allergens for one month, then reintroducing individually to identify food sensitivities triggering immune responses. Dr. Dawn explains xenotransplantation advances with genetically edited pigs beginning full-scale kidney transplant trials. Companies use CRISPR to disable genes causing immune rejection and insert human genes promoting immune tolerance. With only 10% of global kidney patients receiving organs, these could provide unlimited supply. Other innovations include kidneys with thymus tissue to teach immune tolerance and external pig liver systems as transplant bridges. She concludes noting research showing female dogs remember and prefer humans who demonstrate competence at tasks, while male dogs show no preference.

Broadcast from KSQD, Santa Cruz on 11-13-2025: Dr. Dawn discusses a New England Journal of Medicine study examining radiation exposure from medical imaging in over 4 million children showing increased hematological cancer risk. Head and brain CTs deliver highest bone marrow doses, with under-1-year-olds receiving 20 milligrays compared to background radiation of 1 milligray yearly. The study found 3,000 cancers in 4 million children over roughly 10 years, with relative risk increasing 1.6-fold per CT scan. However, methodological flaws include combining US and Canadian cohorts with different data quality, potential reverse causation where imaging detected pre-existing cancers, and arbitrary 6-month latency assumptions are significant flaws in this study.. Despite small absolute risk increases given low baseline cancer rates, she encourages parents to question necessity of repeat scans and request alternatives like MRI when appropriate. She reports on cutting-edge CRISPR therapy using lipid nanoparticles to deliver molecular scissors targeting the ANGPTL3 gene controlling LDL cholesterol production. Recent setbacks in several other CRISPR trials raise issues for unexplained liver toxicity. Concerns include off-target gene editing effects and partially repaired DNA creating mutated proteins triggering autoimmune reactions. Dr. Dawn emphasizes restricting gene therapy to life-threatening genetic diseases with no alternatives until safety improves. Stanford scientists used AI model Evo trained on 9 trillion gene samples to design 300 new bacteriophages from scratch, with 16 phages successfully killing E. coli bacteria. AI tools now predict protein structures, design custom drugs, create antivenoms, invent antibiotics, and break down PFAS forever chemicals. The research represents evolution through computation and requires guardrails on AI's ability to manipulate biological structures. An emailer shares the Rosencare model where hotel chain owner Harris Rosen created self-insured health coverage featuring direct provider contracting, imaging facilities charging one-third to one-half traditional costs, transparent pharmacy benefit management, and zero or $5 primary care copays. Employees receive proactive screening for colonoscopies, mammograms, cholesterol, diabetes, and hypertension during clinic visits. Ninety percent of medicines including insulin cost nothing, with remaining drugs $0-25, and hospital admissions cost flat $750. The model saved $600 million while providing superior preventive care by eliminating insurance middlemen and focusing on early chronic disease detection when 75-85% of costs originate. Dr. Dawn explains abdominophrenic dyssynergia causing bloating unrelated to gas or food. The diaphragm descends and abdominal wall muscles relax, pushing organs forward after meals. CT scans showed lettuce-related bloating involved no intestinal gas changes but demonstrated this abnormal

Broadcast from KSQD, Santa Cruz on 11-06-2025:>/p> Dr. Dawn interviews Cindy Jackonette and Dr. Michael Alexander about a fundraiser for pancreatic cancer awareness on November 15th at Bargetto Winery from 2-5pm, supporting the Santa Cruz Cancer Benefit Group. Dr. Alexander explains pancreatic cancer has only 10-15% five-year survival rates and is difficult to screen for. Screening involves complex endoscopy procedures examining pancreatic ducts, CT scans and biomarker scans. The disease represents 3% of cancer cases but 8% of deaths. Immune checkpoint inhibitors show limited success except in Lynch syndrome patients with DNA repair defects. The Santa Cruz Cancer Benefit Group donates annually to local cancer organizations and is all volunteer-run with minimal overhead. An emailer asks when her 56-year-old half-African American son should get colon cancer screening given his father and uncle both had the disease. Dr. Dawn explains African Americans have increased risk and recommends immediate colonoscopy despite the ideal screening window being 10 years ago. She emphasizes identifying whether he produces polyps, which would require surveillance every 3-5 years. Unlike pancreatic cancer, colon cancer is highly curable when detected early, with death rates dropping 30-40% since colonoscopies became standard in the mid-1990s. She recommends preventive measures including daily 200mg ibuprofen (if no ulcer history) and a high-fiber diet rich in colorful vegetables containing antioxidants that reduce oxidative stress and DNA damage from free radicals. An emailer from Israel asks about supporting his 38-year-old son's rectal adenocarcinoma treatment. Dr. Dawn recommends nutritional strategies including juicing 10 different fruits and vegetables daily, 20mg melatonin for synergy with chemotherapy, vitamin D supplementation, and L-glutamine as primary food for bowel healing and lymphocyte function. She suggests DHA fish oil to enhance chemotherapy effectiveness, green tea for oncogene inhibition, astragalus herb to increase phagocytic activity and natural killer cells, and rotating water-extracted mushroom formulas with beta-glucans, particularly maitake and shitake. Glutamine also protects mucous membranes from radiation burns. Dr. Dawn discusses alarming cancer rate increases among young adults in Corn Belt states including Iowa, Nebraska, Illinois, Minnesota, Indiana, and Kansas. Since 2015, these states show 5% higher cancer rates for ages 15-49 compared to national averages, with particularly elevated kidney and skin cancer rates. Young women face 66% higher skin cancer risk than peers in other states. . Governor Kim Reynolds invested $1 million for research while Bayer's attempt to shield Roundup from lawsuits failed. Dr. Dawn notes Roundup now contains diquat after removing glyphosate. It has taken decades to accumulate evidence of glyphosates harms, She warns that absence of evidence of Diquats being har

Broadcast from KSQD, Santa Cruz on 10-30-2025: Dr. Dawn opens with Halloween-themed scary medical stories, beginning with food toxins lurking in refrigerators and pantries. She explains how molds on grains and nuts, particularly Aspergillus species, produce aflatoxins that bind to DNA and cause liver cancer, making peanuts especially risky. Fusarium on wheat produces trichothecenes and fumonisins damaging cell membranes. Penicillium molds on fruits like apples produce patulin creating reactive oxygen species that harm organs. She advises discarding soft moldy foods entirely since fungal hyphae penetrate deeply, while hard cheeses can have moldy portions cut away. Meat spoilage involves bacteria producing cadaverine and putrescine, with E. coli, Campylobacter, Salmonella, and Clostridium causing severe illness through heat-stable toxins. A caller asks about yogurt-covered peanuts tasting rancid and confirms Botox contains botulinum toxin A in different salt forms, used medically for migraines, hyperhidrosis, and strabismus. The caller also describes paper-thin skin on sun-exposed forearms that bleeds easily. Dr. Dawn explains UV radiation damages collagen and elastin, making blood vessels vulnerable to shear forces. She recommends topical vitamin K products like Dermal K and protective lycra sleeves or gardening gauntlets to prevent injuries, emphasizing the need for annual dermatologic exams after extensive sun exposure. An emailer asks about RSV vaccine recommendations before overseas travel. Dr. Dawn disagreed with the couple's physician, citing US Preventive Services Task Force guidelines recommending RSV vaccination for all adults 60 and older, plus those 50+ with chronic conditions. She discusses FDA-approved home testing options including the PIXEL by LabCorp test for COVID, flu, and RSV, and iHealth rapid tests. She notes RSV point-of-care tests are available to medical practitioners and recommends thorough vaccination before international trips. Dr. Dawn presents a frightening investigation into private equity hospital bankruptcies, focusing on Steward Healthcare's 31 hospitals and Prospect's 16 facilities. Private equity firm Cerberus earned $700 million while Steward 650 documented incidents of deficient care including deaths. One woman died from hemorrhage after vendors repossessed equipment due to unpaid bills. She explains the shell game where companies sell hospital land to Medical Properties Trust, forcing new operators to pay rent while private equity extracts profits. The Brookings Institution study reveals systematic prioritization of investor returns over patient care, with courts failing to prevent these practices despite some states passing protective legislation. She discusses stillbirth rates being significantly underreported, with Harvard research showing actual rates of 1 in 147 pregnancies versus CDC's 1 in 175, worsening to 1 in 95 for black families. Over 70% invo

Broadcast from KSQD, Santa Cruz on 10-23-2025: Dr. Dawn opens with a passionate plea about E-bike safety after observing riders ignoring stop signs and wearing inadequate helmets in Santa Cruz. She explains the physics of collisions, noting that force equals mass times acceleration, and a car hitting an E-bike rider at 20 mph delivers impact equivalent to falling from a two-story building. She emphasizes that 97% of bike fatalities in New York involved helmetless riders, and brain injuries result from the brain striking the skull twice during impact - once on the impact side and again on the opposite side during deceleration. She urges drivers to honk at helmetless riders and calls for stricter helmet law enforcement. An emailer asks about hydroxyapatite in toothpaste. Dr. Dawn traces its origins to NASA research in the 1960s by Dr. Bernard Rubin studying crystal growth for preventing bone and tooth mineral loss in astronauts. Japanese company Sangi acquired the patent and created the first hydroxyapatite toothpaste by 1980, receiving official anti-cavity recognition in 1993. Studies show it matches fluoride's cavity prevention effectiveness by filling microscopic cracks where bacteria take root. It also relieves temperature sensitivity by sealing micro-fractures in enamel that expose the dentin layer, making it especially helpful for people who clench their jaws. Researchers from UC Berkeley and the Allen Institute used electrodes and lasers to study how mouse brains process optical illusions like the Kanizsa triangle. They discovered specialized IC encoder neurons in the visual cortex that fill in missing information, creating complete shapes from partial cues. When these pattern-completing circuits activate inappropriately, they may trigger hallucinations in conditions like schizophrenia. Dr. Dawn explains that illusions occur when the brain perceives something different from actual visual input, while hallucinations create perceptions with no external stimulus. She discusses frontotemporal dementia where visual hallucinations result from protein deposits in the occipital cortex, and notes that a 2021 British Journal of Psychiatry study found hallucination rates varying from 7% in young people to 3% in those over 70. An emailer describes unbearable chronic lumbar pain with degenerative disc disease shown on MRI. Dr. Dawn emphasizes that MRI findings don't necessarily correlate with pain levels, citing shopping mall studies showing equal degenerative changes in people with and without back pain. She stresses checking for sciatica symptoms including leg pain below the knee, sensory differences between sides, calf size asymmetry, and ability to walk on tiptoes and heels. Without these red flags, the degenerative disease likely isn't causing the pain. She warns against unnecessary surgery citing frequent "failed back" syndrome when surgery for a disk image doesn't "fix" the pain. She recommends water

Broadcast from KSQD, Santa Cruz on 10-16-2025: Dr. Dawn explains the 2025 Nobel Prize in Physiology awarded to Shimon Sakaguchi, Mary Brunkow, and Fred Ramsdell for discovering T regulatory cells. Previously, medical teaching held that the thymus only eliminated self-attacking T cells, but Sakaguchi found that removing the thymus from newborn mice caused autoimmune disease, suggesting protective regulatory cells existed. He identified CD4+CD25+ cells that suppress inflammation and can convert other T cells. Brunkow and Ramsdell discovered the FOXP3 gene that controls these cells, linking mutations to severe autoimmune diseases like IPEX syndrome. Tissue-specific Tregs regulate metabolism in fat, maintain gut microbiome tolerance, promote wound healing in skin, and control muscle regeneration. Therapeutic applications include stopping type 1 diabetes, preventing organ rejection, and treating multiple sclerosis. An emailer asks about a study linking soft drinks to depression through gut bacteria changes. Dr. Dawn critiques the cohort association study for establishing only correlation, not causation, with a weak risk ratio of 1.1 representing just 10% increased association. She explains that bacteria can influence food cravings, making it unclear whether sodas change bacteria levels or bacteria drive soda consumption. Without Koch's postulates—isolating bacteria, growing them, and reproducing disease—the causal direction remains uncertain despite statistical significance. Dr. Dawn reads David Whyte's essay on injury as invitation to transformation, exploring how pain reveals vulnerability, changes identity, requires patience, and teaches compassion. She notes this perspective may come easier to men who reach midlife believing they control their bodies, while menstruation disabuses women of that illusion earlier. As a physician, she emphasizes the ego crisis when people transition from healthy to "person with disease," requiring identity restructuring that can shake foundations but also mature and strengthen individuals. A caller responds enthusiastically to the injury essay, citing quotes from André Gide, James Hillman, and Norman O. Brown about how illness opens doors to reality closed to healthy mindedness, how the soul sees through affliction, and how vulnerability is inherent to being human. Dr. Dawn agrees that many religions embrace wounds as paths to spiritual enlightenment and commits to deeper reflection on suffering's role in the human condition. Dr. Dawn discusses cognitive functional therapy for chronic back pain, describing firefighter Joe Lawrence who believed his spine was irreparably damaged until physical therapist Peter O'Sullivan challenged those beliefs. The therapy addresses psychological aspects by teaching that backs need movement, not protection, and that tensing muscles worsens pain. The three-step approach examines pain origins including emotional context, gradually r

Broadcast from KSQD, Santa Cruz on 10-09-2025: Dr. Dawn opens by addressing an emailer's question about safety of low-dose lithium for dementia prevention. She reports finding a two-year double-blind placebo-controlled trial of 61 patients with mild cognitive impairment that showed no kidney damage from therapeutic lithium doses. While low-dose lithium at 2-3 milligrams daily appears safe compared to therapeutic doses of 50-100 milligrams, she notes its calming effects may improve cognition. She discusses over-the-counter hearing aids now available without prescription, ranging from $98 to $999, representing significant savings compared to prescription models costing four times as much. An emailer asks about long-term methotrexate use for psoriasis, reporting declining white blood cell counts and slower healing. Dr. Dawn reviews studies showing that in 13-year rheumatoid arthritis trials, severe side effects occurred in only 3% of patients. She recommends monthly blood monitoring including comprehensive metabolic panels to check liver and kidney function. As an alternative, she suggests apremilast, which showed excellent long-term safety in pooled data from half a million patient years with virtually no liver, kidney, or blood count problems. She also recommends trying phototherapy with tuned red light frequencies and topical treatments before considering drugs like etanercept that carry leukemia and lymphoma risks. Dr. Dawn expands on ultra-processed food dangers, explaining how mechanical processing of carbohydrates accelerates digestion and causes blood sugar spikes that lead to insulin resistance. Steel-cut oatmeal and wheat berries digest slowly and accelerate glucose at a low rate, while instant oatmeal and white bread hit like loud spikes. She emphasizes that processing primarily affects carbohydrates, not proteins or fats. Whole fruits are vastly superior to juices because juicing makes fruit sugars unnaturally available to metabolism. She also warns about hidden microplastics entering food through processing equipment, transport tanks, and packaging, with longer processing and travel distances increasing contamination. Dr.Dawn discusses the health dangers of sedentary behavior, noting that simply walking 20 minutes daily can lower blood pressure without requiring intense exertion. Dr. Dawn offers creative exercise solutions including bouncing on inflatable exercise balls during screen time, keeping weights in bathrooms for tooth-brushing workouts or in other frequently used spaces, doing resistance band exercises while waiting in cars, and practicing single-leg squats for balance. She describes the geriatric "get up and go" test where inability to stand, walk 10 feet, return, and sit within 10 seconds predicts five-year mortality. A caller discusses motivation challenges with his unused NordicTrack equipment. Dr. Dawn suggests making exercise rewarding by listening to en

Broadcast from KSQD, Santa Cruz on 10-02-2025: Dr. Dawn opens by explaining how blood pressure treatment guidelines have been corrected back to 140/90 after the problematic 2015 SPRINT study temporarily changed recommendations to 120/80. That study used ideal measurement conditions - five minutes of quiet sitting, perfect cuff sizes, compliant patients - creating unrealistic targets that caused elderly patients to faint and break hips. The Veterans Administration and major cardiology organizations now recommend treating to 140/90, with statins only for LDL above 190 or 12% ten-year cardiovascular risk. An emailer asks about claims linking Tylenol to autism. Dr. Dawn thoroughly debunks this, explaining that Swedish studies of 2.5 million children found no association when controlling for sibling comparisons. She notes autism rates remained flat from 1960-1990 despite widespread Tylenol use, then spiked after DSM-4 in 1994 and DSM-5 in 2013 broadened diagnostic criteria. Recall bias skews studies since mothers of autistic children are asked leading questions about past Tylenol use during pregnancy when fever treatment was medically necessary. She discusses RFK Jr.'s mixed positions, comparing him to Isaac Newton who excelled at physics but believed in astrology. While criticizing vaccine misinformation, Dr. Dawn strongly supports RFK's stance on ultra-processed foods. She describes NIH researcher Kevin Hall's studies showing people consume 500 extra calories daily on ultra-processed diets versus whole foods, even when nutrients are matched. The US produces 15,000 calories per person daily, with the food industry engineered to promote overconsumption through hyper-palatable fat-sugar-salt combinations. A caller asks about Healthcare 4.0 plans for biometric tracking bracelets and digital twins. Dr. Dawn discusses privacy concerns around constant health monitoring and data collection, noting that while early disease detection could be valuable, mandatory participation raises serious civil liberties issues. She acknowledges voluntary research projects like the Million Man Study but emphasizes the importance of consent and protection against unauthorized data access by advertisers or government agencies. An emailer shares research on ultrasound brain stimulation helmets as alternatives to surgical electrode implants. Dr. Dawn explains how 256-element phased ultrasonic arrays can target brain regions like the visual cortex with high precision mechanical perturbation, potentially treating Parkinson's, Alzheimer's, and depression without surgery. The technology remains experimental, requiring MRI guidance, but could become portable and dramatically improve quality of life for neurological conditions currently requiring invasive deep brain stimulation. A caller with adrenal cancer asks about fasting-mimicking diets. Dr. Dawn explains that 14-hour fasting before chemotherapy improves outcomes

Broadcast from KSQD, Santa Cruz on 9-25-2025: Dr. Dawn opens with disturbing whistleblower allegations from Patrick Chase about organ transplant corruption. He claims poor patients at Parkland Hospital were systematically denied kidneys that were redirected to wealthier patients at UT Southwestern Medical Center. In 36 documented cases, doctors rejected kidneys as unsuitable for Parkland patients, then transplanted those same organs at the prestigious academic hospital. Chase alleges financial incentives corrupt the entire system, from procurement organizations to waiting list management. She discusses widespread scientific fraud in medical journals, citing research about PLOS journal showing 45 editors facilitated acceptance of fraudulent papers at rates far exceeding chance. These editors represented only 1.3% of reviewers but were responsible for 30% of retracted articles. Paper mills now use AI to generate fake studies with fabricated data, selling authorship to academics seeking publication credits. This undermines evidence-based medicine when treatment guidelines rely on potentially fraudulent research. Dr. Dawn introduces holy basil as a sleep aid beyond melatonin, explaining how its active compound ocimum lowers cortisol and inhibits orexin pathways that promote wakefulness. Unlike melatonin which signals sleep onset, holy basil helps maintain deep sleep by preventing middle-of-night stress spikes. She recommends 500 milligrams of aqueous leaf extract, noting this Ayurvedic herb may be particularly helpful for menopausal women experiencing sleep disruption. She warns about medication-induced osteoporosis, revealing that proton pump inhibitors increase hip fracture risk by 217% after four years of use by impairing calcium absorption and triggering parathyroid hormone release. Antidepressants pose similar risks, with SSRIs increasing fracture risk by 68% and causing women to lose bone 1.6 times faster than non-users. Cancer treatments like androgen deprivation therapy cause severe bone loss, with 81% of long-term users developing osteoporosis. Dr. Dawn challenges cholesterol treatment guidelines, explaining that Quest Labs' recommendation for LDL under 100 contradicts actual medical standards. The Veterans Administration only recommends statins for LDL above 190 plus high cardiovascular risk, or 12% ten-year risk calculated using multiple factors. She criticizes the focus on cosmetic cholesterol numbers while ignoring that high-dose statins increase diabetes risk, which is a greater health threat than elevated LDL alone. A caller describes experiencing severe ear itching followed by facial puffiness after a haircut. Dr. Dawn explains this likely represents a histamine-mediated allergic reaction, possibly triggered by salon products rather than the haircut itself. She advises getting ingredient lists from the salon to identify potential allergens and notes that bilateral sympt

Broadcast from KSQD, Santa Cruz on 9-18-2025: Dr. Dawn opens by establishing her psychobiology background and introducing the neurohormonal axis connecting mind and body. She describes revolutionary research published in Nature Neuroscience showing that simply seeing sick people in virtual reality triggers actual immune responses. The study used VR avatars displaying infection symptoms approaching participants, measuring brain activity with EEG and fMRI while analyzing blood samples for immune cell changes. The research demonstrates that infectious avatars approaching in virtual reality activate the same immune pathways as actual flu vaccination. Brain areas including the salience network and peripersonal space system detect potential threats and communicate with the hypothalamus to trigger white blood cell activation. Proximity matters - threats 20 feet away don't trigger responses, but approaching threats do. Dr. Dawn explains the sophisticated methodology, including 128-channel EEG monitoring and flow cytometry analysis of immune markers. Participants showed faster reaction times when infectious avatars approached compared to neutral ones, demonstrating subconscious threat assessment. The study reveals built-in disgust responses that evolved to protect against pathogens. She comments on how her medical training rewire the protective disgust reaction through repeated exposure.. She transitions to discussing stress effects on gastrointestinal function, explaining how the gut-brain axis operates through the vagus nerve and neurohormonal pathways. The adrenal glands produce both immediate epinephrine responses and longer-term cortisol release, with chronic stress leading to digestive disruption, increased intestinal permeability, and microbiome changes that can trigger food sensitivities and autoimmune conditions. Dr. Dawn details the difference between acute and chronic stress responses in the gut. Acute stress redirects energy from digestion for fight-or-flight responses, while chronic stress causes mast cell activation, histamine release, mucus layer thinning, and bacterial overgrowth. These changes can lead to irritable bowel syndrome, increased food allergies, and even celiac disease in genetically susceptible individuals. The discussion covers various brain networks including the default mode network active during rest, the central executive network for problem-solving, and the salience network that switches between them when detecting important stimuli like threats, food, or reproductive opportunities. Functional MRI studies show these networks' activity patterns and their connections to immune system regulation through the hypothalamus. Dr. Dawn emphasizes practical implications for modern life, warning that constant screen exposure and doom-scrolling activate chronic stress responses unnecessarily. She recommends avoiding phones upon waking, spending time outdoors

Broadcast from KSQD, Santa Cruz on 9-11-2025: Dr. Dawn announces COVID-25/26 vaccines are now available at Safeway with same-day appointments, urging listeners to schedule quickly due to potential supply shortages amid uncertain federal vaccine policies. She discusses promising research on metformin for knee osteoarthritis in obese patients. Studies show metformin users lost half as much cartilage (0.75% vs 1.5%) over four years and had reduced knee replacement risk. The mechanism involves AMPK protein kinase pathways that reduce inflammation and cellular energy storage, with benefits independent of weight loss effects. Dr. Dawn warns hunters about blue pig meat from wild boars that consume rodenticide, which acts like warfarin to prevent blood clotting. The anticoagulant creates blue-tinted tissue that cooking cannot eliminate, making such meat dangerous for consumption during hunting season from September through November. She criticizes the elimination of women's health research funding, highlighting how the Eunice Kennedy Shriver Institute has advanced medical knowledge benefiting everyone. Dr. Dawn notes that $2.5 billion in research was rescinded for containing terms like "women" and "female," creating dangerous knowledge gaps when women experience different disease symptoms and medication responses than men. The brown rice versus white rice debate centers on arsenic content, with brown rice containing about 138 parts per billion compared to 93 in white rice. While both remain below WHO safety limits, children are especially vulnerable. Dr. Dawn recommends diverse grain options and specific cooking methods like soaking, rinsing, and using excess water to reduce arsenic levels. A caller asks about glutathione supplementation, specifically gamma-glutamyl cysteine products. Dr. Dawn explains how these precursors bypass liver metabolism to deliver glutathione to cells, while discussing the balance between oxidative and reductive stress. She notes individual genetic variations can affect supplement responses and emphasizes measuring markers rather than expecting immediate symptomatic improvements. Another caller inquires about histamine intolerance causing puffy eyes and food reactions. Dr. Dawn explains histamine's role as a neurotransmitter, sources in fermented foods and gut bacteria, and genetic enzyme deficiencies in DAO and histamine transferase. She recommends cromolyn sodium eye drops and systematic food elimination, particularly targeting recently increased consumption of chai tea and smoked brisket. Dr. Dawn concludes with news about an AI tool called FaceAge that predicts biological age and survival rates from facial photographs. Trained on 60,000 photos of people over 60, the system achieved 80% accuracy in predicting six-month survival for terminal cancer patients compared to 61% accuracy for human doctors, potentially offering a non-invasive healt

Broadcast from KSQD on 9-04-2025: Dr. Dawn opens by criticizing new FDA restrictions on simultaneous COVID and flu vaccinations, calling out vaccine regulator Vinay Prasad for creating artificial shortages. She explains that while no formal studies test multiple vaccines together, decades of safe practice demonstrate effectiveness. The FDA's requirement for separate testing ignores practical evidence and threatens vaccine supply chains during critical flu season. She discusses Oregon research suggesting adults may not need tetanus boosters every 10 years, but warns this misses the pertussis component. Dr. Dawn explains that acellular pertussis vaccines only provide 4-year immunity, making adult boosters essential to prevent whooping cough transmission to vulnerable infants. The focus should remain on pertussis prevention rather than tetanus economics. California, Oregon, and Washington announced a West Coast Health Alliance to maintain scientific integrity in public health policy amid federal changes. Dr. Dawn supports this states' rights approach to vaccination recommendations based on trusted medical organizations, expressing concern about potential vaccine shortages if manufacturers reduce production due to uncertain federal demand. An emailer shares an AI-generated analysis comparing tuberculosis and Lyme disease. Dr. Dawn critiques the AI's inaccuracies, noting that while tuberculosis may be present in 25% of people globally s the AI reports (she did not fact check this), the distribution is very uneven and cases in the US are low which we know since accurate latent TB testing is readily available in the US. She warns against AI's tendency to incorporate conspiracy theories due to a bias which favors frequency vs accuracy and emphasizes the importance of fact-checking AI-generated medical content. Dr. Dawn addresses FDA concerns about unregulated GLP-1 drugs, warning about counterfeit semaglutide and tirzepatide from questionable sources. She discusses dosing errors, non-FDA-approved compounds appearing in gray markets, and the rare but serious cancer risk for people with multiple endocrine neoplasia syndromes - affecting 1 in 30,000 people who could develop hormone-producing cancers. A caller asks about genetic testing for GLP-1 cancer risk. Dr. Dawn explains that complete genome testing costs around $1,000 and requires professional interpretation. She discusses the economic challenges of testing 30,000 people to prevent one cancer case, while acknowledging that obesity's health risks generally outweigh the small cancer risk for most patients. She examines FDA challenges in approving MDMA for PTSD treatment, explaining the "Catch-22" of blinding studies when drugs cause obvious consciousness changes. Dr. Dawn describes how psychedelic research faces unique obstacles requiring 8-10 hour supervised sessions with therapists, making traditional double-blind studies nea

Broadcast from KSQD, Santa Cruz on 8-28-2025: Dr. Dawn opens with concerning research about PFAS (forever chemicals) found in feminine hygiene products. Chinese and American studies reveal significant concentrations in paper diapers, sanitary pads, and especially period underwear, with some products containing up to 77,000 parts per million. These compounds can absorb through skin and never break down in the environment, raising health concerns for products used in intimate contact. She shares research on vitamin K (MK7) for nocturnal leg cramps in older adults. A study of people 65 and older showed that 180 micrograms of menaquinone-7 reduced cramp episodes by half over two months while placebo group episodes doubled. This form of vitamin K also helps direct calcium to bones rather than arteries when taking calcium and vitamin D supplements. Dr. Dawn explains how gut bacteria are evolving to digest food thickeners like guar gum found in ketchup, salad dressing, and toothpaste. Previously considered non-digestible, these cellulose-based compounds are now being broken down by bacterial enzymes that develop when people eat high-fiber diets, potentially adding hidden calories to processed foods beyond what labels indicate. An emailer asks about Botox brain effects after reading a study in Advanced Science. Dr. Dawn critiques the research methodology, explaining that the organoid model using fetal cells doesn't replicate real-world conditions. She argues the cosmetic doses used are orders of magnitude smaller than the doses used in the study. The study concentrations are much higher than doses used in even the most aggressive therapeutic applications and concludes the study doesn't provide compelling evidence for brain toxicity concerns. Another emailer inquires about myalgia encephalomyelitis/chronic fatigue syndrome genome research. Dr. Dawn explains that while GWAS studies identifying eight genetic loci are scientifically interesting, they don't provide practical diagnostic tools or treatment insights. She notes the resemblance of ME/CFS to long COVID and describes the hallmark symptom of post-exertional malaise lasting days after activity. Dr. Dawn presents encouraging dementia prevention research showing Mediterranean diet benefits. The study found 13% reduced dementia risk overall, with 25% reduction for those improving adherence. Most significantly, people with the high-risk APOE4 gene variant showed the greatest protective effect from eating leafy vegetables, fish, whole grains, and limiting processed foods. She provides an extensive discussion of hormone therapy for mental health, criticizing the medical field's neglect of hormonal causes of depression and anxiety. Dr. Dawn explains how 35% of men over 45 are testosterone deficient and describes perimenopause effects on women's mental health, including 30% increased depression risk and 112% increased bipolar disord

Broadcast from KSQD, Santa Cruz on 8-21-2025: Dr. Dawn opens with disturbing research linking respiratory infections to breast cancer reactivation. Studies show increased breast cancer deaths during COVID beyond screening delays, suggesting viral infections may awaken dormant cancer cells through inflammatory signals. Mouse models demonstrate that influenza infection can increase metastatic burden up to 1000-fold by triggering neutrophil extracellular traps that act as growth signals for sleeping cancer cells. She covers neuroimmune crosstalk in lung fibrosis research, where mice lacking pain receptors developed worse scarring when exposed to lung injury. The absence of pain signals failed to trigger natural inflammation suppressors, leading to increased neutrophil activity and inflammatory nets that contributed to tissue damage. New food spoilage detection technology uses pH-sensitive dyes in packaging that fluoresce or change color when bacterial metabolism produces acids. This could prevent foodborne illness from contaminated deli meats and dairy products by providing visual warnings before consumption, particularly important for high-risk foods like lunch meats and mayonnaise. Dr. Dawn warns about diquat replacing glyphosate in Roundup products, potentially creating 200 times more toxicity. The new compound suppresses gut lining proteins, creating leaky gut and allowing bacterial toxins into the bloodstream, while causing permanent kidney, liver, and lung damage. Most countries have banned diquat, but it remains available in American stores. Research reveals that lactose intolerance can cause intense nightmares through gut-brain connections. Montreal studies found that people with dairy sensitivity experience more frequent, distressing dreams that improve significantly when dairy is eliminated from their diet. The mechanism likely involves gastrointestinal discomfort causing microarousals that make dreams more vivid and memorable. She describes revolutionary remote-controlled probiotics combining genetically modified E. coli with pill cameras. These bacterial robots can detect inflammation, produce therapeutic compounds on command, and communicate through bioluminescence. Applications include targeted inflammatory bowel disease treatment where bacteria manufacture anti-TNF nanobodies when activated by LED signals from swallowed capsules. An emailer with recurring diverticulitis asks about surgical options versus dietary management. Dr. Dawn explains the structural causes of diverticular disease and the vicious cycle created by repeated antibiotic treatments that damage gut microbiomes. She emphasizes the importance of dramatically increasing fiber intake and addressing underlying leaky gut issues that may contribute to the condition. A caller asks about foods for better bowel movements while managing diabetes and taking Wegovy. Dr. Dawn recommends ground fla

Broadcast from KSQD, Santa Cruz on 8-14-2025: Dr. Dawn shares the story of Tim Fried, a construction worker who deliberately exposed himself to 850 snake venom doses over 18 years to build immunity. An immunologist developed antivenom from Fried's antibodies that neutralizes venom from 19 deadly snake species, potentially saving thousands of lives annually from snakebite deaths. She describes cuttlefish sign language research revealing four specific arm movements. The cuttlefish respond to videos and water vibrations from these signs, suggesting complex communication abilities rather than simple mimicry, potentially comparable to octopus intelligence. New research challenges the assumption that Neanderthals were hyper-carnivores. While bone nitrogen levels suggested a meat-only diet, dental evidence showed plant consumption. Researchers now theorize Neanderthals ate maggots from rotting meat, which contain 43% more nitrogen than flesh and would explain the contradictory evidence between bone chemistry and tooth wear patterns. CPR guidelines may soon from the traditional ABC approach (airway, breathing, circulation) to focusing immediately on chest compressions. Research on 45 collapsed athletes showed that 27 who received inappropriate airway clearing died or remained comatose, while three who received immediate rapid chest compressions survived with potential for rehabilitation. The recommendationcould become 100-120 compressions per minute without preliminary airway management. Dr. Dawn presents reassuring statistics about spinal abnormalities in pain-free adults over 60. MRI studies show 90% have disc degeneration, 80% have disc bulges, and 40% have protrusions - yet these individuals have no back pain. This raises questions about attributing back pain to imaging findings when so many similar abnormalities exist in asymptomatic people. Australian cockatoos have learned to operate drinking fountains for entertainment rather than necessity. Researchers observed 70 birds attempting and 40 successfully using fountains, waiting in organized lines and taking turns, despite easier water sources being available nearby. An emailer asks about Essiac tea for cancer prevention. Dr. Dawn explains this herbal blend of burdock root, Indian rhubarb, sheep sorrel, and slippery elm shows promise in laboratory studies but lacks quality human research. While not harmful, no studies demonstrate reduced cancer recurrence rates, though the antioxidant properties may provide general health benefits. Another emailer inquires about lithium supplements for Alzheimer's prevention. Dr. Dawn discusses research showing lower brain lithium levels in Alzheimer's patients and how amyloid plaques trap lithium. Studies suggest lithium orotate (unlike lithium carbonate) isn't absorbed by plaques and may help memory in mice. Low-dose lithium orotate appears safe and mildly calming for humans. </l

Broadcast from KSQD, Santa Cruz on 8-07-2025: Dr. Dawn opens with groundbreaking news about the first successful islet cell transplant for type 1 diabetes without immunosuppression. A 42-year-old man received gene-edited donor cells that were modified to avoid immune rejection by removing tissue compatibility markers and adding protective proteins. The transplanted cells in his forearm began producing insulin autonomously, reducing his A1C by 42% over 12 weeks. This breakthrough could lead to off-the-shelf diabetes treatments without the cancer and infection risks of immunosuppressive drugs. She critiques a case where a patient was prescribed an expensive new osteoporosis drug without trying conservative treatments first. Dr. Dawn explains how this monoclonal antibody works by blocking sclerostin, essentially cutting the brake lines on bone formation. While effective for severe osteoporosis, the drug increases heart attack and stroke risk by 15%. She advocates for trying lifestyle changes, exercise, and established treatments before resorting to newer, more dangerous medications with questionable risk-benefit ratios. A caller asks about a pustular rash on his upper body that his acupuncturist suggests might be related to COVID vaccination. Dr. Dawn addresses the distribution pattern of the rash, suggesting possible causes like hot tub folliculitis or topical allergies based on the location. She discusses how to evaluate rashes by their characteristics and distribution rather than jumping to vaccine-related conclusions. The caller inquires about vaccine development timelines and whether rushed approval during COVID might have missed serious side effects. Dr. Dawn explains that mRNA vaccine technology existed for 10 years before COVID and discusses her theory about vaccine side effects. She describes how spike proteins may temporarily deplete anti-inflammatory mechanisms, leading to flare-ups of existing conditions like eczema or arthritis, but emphasizes these effects are generally temporary and rebuilding occurs over time. Caller asks about RFK Jr.'s stance on vaccine research and the long-term implications of reducing vaccine development. Dr. Dawn provides a nuanced response about problems with the current vaccine system, including government-guaranteed markets that incentivize overproduction of vaccines. She discusses the evolution from essential vaccines for devastating diseases to newer vaccines for less critical conditions, explaining the economic forces that drive development and the resulting over-vaccination in healthy populations versus the need to protect vulnerable individuals. Dr. Dawn concludes with an innovative medical technology - a robot mattress designed to prevent pressure ulcers in immobilized patients. The mattress contains 1,260 independently controlled pistons that create undulating checkerboard patterns, alternating pressure points to stimulate blood flow. R

Broadcast from KSQD, Santa Cruz on 8-31-2025: Dr. Dawn interviews Katherine Rockwood and Jess Stevens, both registered nurses and breastfeeding advocates, during International Breastfeeding Month. They discuss community events including breastfeeding cupcakes at hospitals, partnerships with WIC (Women, Infants & Children) nutrition programs, and upcoming festivals featuring educational booths from various healthcare organizations. The conversation covers how these events aim to normalize breastfeeding and provide support resources for new mothers. The discussion explores milk donation programs, with Jess explaining her experience as a milk donor after becoming an "overproducer." They detail the screening process involving health questionnaires, blood tests, and milk quality checks before donation. The conversation addresses the high cost of donor milk at approximately $30 per ounce and insurance challenges, highlighting cases where fundraising helped provide donor milk for babies whose mothers couldn't breastfeed due to medical conditions like cancer. Dr. Dawn comments that breastfeeding a baby is like giving them a $100.00 restaurant meal daily. Katherine and Jess explain the superior benefits of breast milk over formula, particularly for premature babies who face risks like necrotizing enterocolitis from formula feeding. They discuss how the mother's breast milk composition automatically adjusts it's content for premature infants and how there is a 28-day window for establishing milk supply that affects long-term breastfeeding success. The nurses describe their support programs, including Katherine's "Baby Talk" group meetings where experienced mothers help newcomers learn breastfeeding techniques. They explain how group settings provide encouragement and demonstrate proper latching through observation and imitation. The discussion includes practical tips like playing jazz music and creating calm environments to facilitate milk letdown, drawing from Katherine's background in jazz clubs. Dr. Dawn explores the science behind breast milk, including human milk oligosaccharides that feed beneficial gut bacteria and establish healthy microbiomes. The conversation covers how breast milk changes throughout the day, with higher melatonin levels in evening milk, and how the antibody percentage composition shifts when babies are sick. Amazingly, breast milk becomes more yellow in color due to increased antibodies. They discuss how milk adapts for different aged children and even changes caloric content based on baby's gender with males receiving 25% more calories. The discussion addresses workplace and societal challenges for breastfeeding mothers, including the need for proper lactation rooms and supportive employers. They mention legal requirements for lactation spaces in California government buildings and the particular challenges faced by agricultural workers who lack adequate facili

Broadcast on KSQD, Santa Cruz on 7-24-2025: An emailer from Israel asks about mouth taping for sleep benefits, prompting Dr. Dawn to review a comprehensive study examining social media claims. She discusses the limited evidence base for most purported benefits like better sleep, oral health, and reduced snoring. The research reveals only mild sleep apnea showed meaningful improvement, while most other claims lack scientific support despite widespread promotion on social media platforms. Dr. Dawn reports on American scientists fleeing to France due to research funding cuts and political pressures. She describes how 300 American researchers have applied to just one French university, citing eliminated grants and demands to justify their basic science work. The brain drain parallels Europe's post-WWII exodus to America, but now affects climate research, gender studies, biology, and even NASA astrophysics programs. She introduces Salsalate, an aspirin-related drug from 1876 being reconsidered for diabetes treatment. Dr. Dawn explains how this salicylate works through anti-inflammatory pathways to reduce insulin resistance. Recent trials show promising results for glucose control and metabolic improvements, potentially offering an older, affordable alternative to newer diabetes medications. Dr. Dawn describes breakthrough surgical robot technology that successfully removed organs without human guidance. The system uses dual AI components for vision and instrument control that communicate with each other to correct mistakes. She notes the progression toward live animal testing as the next development phase. She explores revolutionary nanobots based on tiny algae cells that can navigate the human body for targeted drug delivery. These microscopic robots use flagella for movement and can be guided by magnets and ultrasound to reach specific organs like kidneys. The technology offers potential for precise chemotherapy delivery while avoiding healthy tissues. An emailer questions gabapentin's connection to cognitive decline after being prescribed the medication for sleep. Dr. Dawn challenges the study's methodology, noting that early dementia symptoms include insomnia, which leads to sleep medication prescriptions. She argues the correlation may reflect pre-existing cognitive decline rather than drug-induced impairment. Dr. Dawn presents alternatives to knee replacement surgery for patients hesitant about major procedures. She details innovative nerve ablation techniques that rewire pain signals by connecting sensory nerves to motor nerves, potentially providing permanent relief. Additional options include radio frequency ablation and blood vessel embolization to reduce inflammation-related pain. She highlights Alice Walton's new medical school in Arkansas focusing on preventative medicine and whole-person care. The curriculum emphasizes lifestyle factors, community servi

Broadcast from KSQD, Santa Cruz on 7-17-2025: Dr. Dawn interviews Dr. Drew Richard, a first-year resident at Dominican Santa Cruz Family Medicine Residency. Dr. Richard discusses his motivation to bridge socioeconomic health disparities and his experience creating educational cooking episodes featuring cultural dishes from medical students. He explains his philosophy that medicine should help people cultivate compassion and his belief in the fundamental capacity for human goodness. The conversation explores the evolution of medical training and communication skills. Dr. Dawn contrasts today's team-based collaborative approach with the hierarchical, authoritarian medical culture of the past. They discuss how modern medicine emphasizes interprofessional collaboration, with Dr. Richard noting improved learning environments where faculty are more forgiving of mistakes while maintaining high standards for patient safety. A caller asks about functional medicine's approach to intangible factors like intention, purpose, attitude, energy, and alternative therapies like sound healing. Dr. Dawn explains the functional medicine matrix that places mental, emotional, and spiritual aspects at its center, discussing how these factors influence disease response and treatment outcomes. She describes the body's electrical field and energy medicine principles from her acupuncture practice. Dr. Richard addresses the caller's question about sound healing, suggesting that practitioners frame these concepts in familiar terms rather than using unfamiliar terminology. He recommends starting conversations about therapeutic music by asking patients about their favorite songs rather than immediately introducing concepts like sound baths, making these healing modalities more accessible and less intimidating. The discussion shifts to music's neurological benefits, with Dr. Dawn citing research showing that singing and music-making promote brain health and neuroplasticity. Studies demonstrate that piano practice increases gray matter, improves cognitive flexibility, and enhances auditory working memory in older adults. They explore how music engagement, whether through listening or active participation, releases dopamine and provides emotional regulation benefits. Dr. Richard shares his personal musical background as a drummer and discusses the bonding effects of group music-making. Dr. Dawn describes her experiences with choral singing and four-part harmony, explaining how shared musical vibrations create feelings of communion and connection. They explore how music affects the body's vibrations and blood flow, touching on everything from opera to movie soundtracks. The conversation turns to Dr. Richard's surfing experiences as part of his residency cohort's wellness activities. He describes overcoming ocean fears and discovering unexpected joy in the sport, noting how the entire residency class has emb

Broadcast from KSQD, Santa Cruz on 7-10-2025: Dr. Dawn responds to an email about lion's mane mushroom blood thinning properties. Lion's mane contains hericenones that inhibit platelet aggregation but promote nerve cell growth. People on blood thinners like Eliquis or those with bleeding disorders should stop these supplements before surgery. She recommends lion's mane for cognitive preservation effects despite bleeding risks, emphasizing the need to balance benefits versus risks. An emailer asks about Fatty15 (C15:0 pentadecanoic acid) supplements marketed for longevity. Dr. Dawn finds promising research, however, most studies are in animals with limited human data. She warns against over-supplementation and recommends food-first approaches, suggesting cheaper alternatives like berberine may provide similar benefits. A visiting guest asks about continuing L-arginine after blood pressure normalized. Dr. Dawn recommends continuing L-arginine as it helps produce nitric oxide and prevents age-related arterial stiffening. She explains how blood vessel elasticity decreases with age, creating feed-forward cycles leading to permanent hypertension. The guest also asks about iodine safety - Dr. Dawn confirms 1mg daily is safe, noting Japanese populations consume up to 4mg daily without problems. Another visiting guest inquires about memory-boosting supplements (nootropics). Dr. Dawn identifies nicotine and caffeine as effective options, mentioning she uses nicotine patches for test-taking focus. She discusses lion's mane as effective for cognitive enhancement and coffee blends combining both ingredients. A caller asks about tirzepatide (Mounjaro) for weight loss at age 73, concerned about muscle loss. Dr. Dawn emphasizes the importance of branched-chain amino acids and 20-30 grams of protein before exercise for older adults to build muscle protein. She explains younger people can build muscle while fasting, but older adults need circulating protein during exercise to activate muscle-building DNA. She recommends alternating upper and lower body workouts and checking testosterone levels. Another caller asks about rapid resting pulse rate (80-100 bpm) at age 74. Dr. Dawn suggests checking blood pressure, as low blood pressure can cause compensatory heart rate increases. She explains age-related changes in blood vessel reflexes that can cause blood pooling in legs and orthostatic changes. The caller also complains about pharmaceutical advertising, prompting Dr. Dawn to criticize direct-to-consumer drug marketing for creating artificial needs through emotional manipulation. Dr. Dawn warns against P-Tau217 blood testing for Alzheimer's screening, calling it inadequate for general population screening. The test has poor predictive value below level 10, creating many false positives in low-risk populations. She criticizes associated drugs like donanemab (Kisunla) for severe side effects

Broadcast from KSQD, Santa Cruz on 7-03-2025: Dr. Dawn responds to an email about vitamin D and statin interactions, explaining how statins may prevent vitamin D's longevity benefits by interfering with CoQ10 production. She references a study showing vitamin D preserved telomeres and prevented aging over 3-4 years, but benefits disappeared in statin users. For borderline high LDL, she recommends testing for large versus small particles and oxidized LDL rather than treating with statins or red yeast rice. Red yeast rice may also block CoQ10 production, potentially negating vitamin D benefits. She discusses the critical problem of overmedication in elderly patients through a story of a 75-year-old taking 21 prescription drugs who improved dramatically when reduced to eight medications. Multiple specialists practicing standard care in isolation create dangerous polypharmacy without coordination. HIPAA privacy laws prevent medication sharing between providers, while electronic medical records remain siloed and incompatible. England's pilot program will provide whole genome screening for every newborn within 10 years, assessing hundreds of disease risks and enabling personalized medicine. While beneficial for identifying genetic disorders and drug metabolism variations like 2D6 mutations affecting tamoxifen effectiveness, Dr. Dawn expresses concern about government surveillance implications. Unlike voluntary phone tracking, this represents involuntary comprehensive genetic monitoring of citizens unable to provide informed consent. She describes alarming research showing cancer cells steal mitochondria from nerve cells by extending tubes and sucking out energy-producing organelles. This behavior helps cancer cells survive the hostile journey through bloodstream during metastasis. Turbocharged cancer cells with stolen mitochondria generate more energy and survive better when subjected to physical stress mimicking bloodstream travel. Dr. Dawn explores the parasitic amoeba Entamoeba histolytica, which causes intestinal disease but can become invasive, liquefying organs through tissue destruction. The parasite kills cells without eating them immediately, then consumes fragments and displays stolen cellular proteins on its surface to fool the immune system, potentially leading to CRISPR-based treatments or targeted drugs. She discusses converting plastic waste into acetaminophen using modified E. coli bacteria. Researchers chemically degrade PET plastic into precursor molecules, then use bacterial enzymes to complete synthesis into paracetamol with 92% efficiency. This transforms environmental waste into globally important medication, though she notes acetaminophen risks for regular drinkers due to toxic liver metabolites. MIT research reveals that AI writing assistance reduces brain engagement, memory, and sense of authorship. Students using ChatGPT showed lower neural connectivi