About this episode
Naloxone! Literally everywhere! Naloxone is now OTC, so what now??? The PAIN GUY™ will discuss all things opioid antagonists including naloxone, naltrexone, and even nalmefene in this episode of the PAIN POD! This episode is for all of society, with the usual sprinkle of pharmacology. Come one, come all, to the Pain Pod!!! References • https://www.medpagetoday.com/neurology/generalneurology/60632 • Moss, R.B., Carlo, D.J. Higher doses of naloxone are needed in the synthetic opioid era. Subst Abuse Treat Prev Policy 14, 6 (2019). • https://www.cnn.com/2018/11/06/health/naloxone-expiration-date-potency-study/index.html • Hossain MF, Rashid M, Mullins R, Davis T, Kimble C, Sarkar S; Charles “CK” Babcock. Chemical stability of naloxone products beyond their labeled expiration dates. J Opioid Manag. 2022 Jan-Feb;18(1):39-46. • Comparison of Relapse Rates Between Drug Addiction and Other Chronic Illnesses JAMA. 284: 1689-1695, 2000. • https://www.vice.com/en/article/qv7jmp/heroin-overdose-parties-are-a-dehumanizing-myth • https://naloxoneautoinjector.com/ • https://www.statnews.com/2023/03/28/opioid-overdose-naloxone-industry-profits/ • Katzman JG, Takeda MY, Bhatt SR, Moya Balasch M, Greenberg N, Yonas H. An Innovative Model for Naloxone Use Within an OTP Setting: A Prospective Cohort Study. J Addict Med. 2018 Mar/Apr;12(2):113-118. • Hatfield E, et. al. Use of low-dose naltrexone in the management of chronic pain conditions. JADA. December 2020. JADA 151(12). • https://www.reuters.com/business/healthcare-pharmaceuticals/addiction-drug-shows-promise-lifting-long-covid-brain-fog-fatigue-2022-10-18/ • https://www.painmedicinenews.com/Online-First/Article/09-21/FDA-Orphan-Drug-Low-Dose-Naltrexone/64707 • https://www.investopedia.com/ask/answers/06/orphandrugstatus.asp • https://www.statnews.com/2023/03/28/opioid-overdose-naloxone-industry-profits/