002 How long does the growth stimulus last after a training session?

In this second episode, Jake Doleschal and Chris Beardsley break down the York Barbell Mr America Course, a program from 1951 that evolved from the earlier Milo Barbell plan. They explore what changed in the decades following the first mass-produced bodybuilding programs, including the introduction of sets, improved exercise selection, and targeted variations. They then connect these historical shifts to modern muscle physiology, focusing on how long the hypertrophy stimulus lasts after a workout, and why full-body training remains superior. Key topics: How the York Barbell Course built on the Milo plan Why the shift from reps to sets was a turning point How to interpret MPS/MYOPS data without confusing stimulus and damage Why most hypertrophy occurs within 24–36 hours of a session How this insight changes everything about training frequency