The Caring Neurologist

4d ago

Welcome to another episode of The Caring Neurologist! Today, host Dr. Sandeep Thakkar dives into a truly fascinating topic that’s changing the way we think about Parkinson’s disease. When most people hear “Parkinson’s,” they picture tremors and movement challenges. But what if the earliest warning signs of this brain disorder actually begin in the gut? In this episode, Dr. Sandeep Thakkar unravels the intricate connection between our digestive system and brain health. They discuss how early symptoms like constipation, gut inflammation, and changes in the microbiome might signal Parkinson’s long before the first tremor appears. You’ll learn about the vital role of the vagus nerve, the mysterious behavior of the alpha synuclein protein, and the potential for future diagnostics that could detect Parkinson’s through a simple gut test. Whether you’re living with Parkinson’s, caring for someone who is, or simply curious about how the body and brain communicate, this episode will leave you with new insights and maybe some hope about the future of prevention and early intervention in neurological disease. So grab your headphones, settle in, and get ready to discover why your next healthy choice could start with your gut! 00:00 Gut-Brain Link in Parkinson's 04:43 Gut-Brain Connection and Coordination 07:25 Gut Health and Mental Clarity 10:04 Gut-Brain Axis: Cause or Effect? 14:05 Vagus Nerve's Role in Parkinson's 19:59 "Gut Health and Brain Connection" 20:53 Gut Health and Microbiome Research 24:15 "Parkinson’s Diagnosis via Gut Biomarkers" 27:38 Diet's Role in Gut Health 31:26 Oral Bacteria's Link to Disease 33:51 Parkinson's: Gut Health Matters The Caring Neurologist - Podcast Website - https://thecaringneurologist.com/ Dr. Sandeep Thakkar - LinkedIn - https://www.linkedin.com/in/sandeep-thakkar-do-798a2499/ Dr. Sandeep Thakkar - Clinic - https://ocparkinsons.com/about-mdpds/our-team/dr-thakkar/ TopHealth - https://tophealth.care/ “Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”

Dec 2

Welcome back to The Caring Neurologist, where science, stories, and breakthrough discoveries meet compassionate care. In today’s episode, host Dr. Sandeep Thakkar takes you on a deep dive into the fascinating journey of Levodopa, the drug that transformed Parkinson’s treatment and remains the gold standard decades after its introduction. From its ancient roots in Ayurvedic medicine to the groundbreaking trials that redefined patient care, you’ll learn how Levodopa works, why it’s so effective, and what the latest innovations in delivery systems mean for the future. Whether you’re a patient, caregiver, or just curious about neurological breakthroughs, this episode promises practical insights, myth-busting moments, and a renewed sense of hope for those navigating life with Parkinson’s. 00:00 "Levodopa: History and Significance" 04:38 Improved Levodopa Delivery Options 09:52 Levodopa vs Dopamine Agonists 13:37 Levodopa: Debunking Longevity Myths 16:32 Assessing Quality of Life in Parkinson's 19:03 "Protein-Rich Meals Impact Medication" 23:05 Advancements in Levodopa Therapies 25:42 "Learning Prevents Cognitive Decline" 28:35 Levodopa: Key in Parkinson's Care The Caring Neurologist - Podcast Website - https://thecaringneurologist.com/ Dr. Sandeep Thakkar - LinkedIn - https://www.linkedin.com/in/sandeep-thakkar-do-798a2499/ Dr. Sandeep Thakkar - Clinic - https://ocparkinsons.com/about-mdpds/our-team/dr-thakkar/ TopHealth - https://tophealth.care/ “Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”

Oct 5

Welcome back to The Caring Neurologist, where science meets storytelling and every conversation brings us closer to better care. In this episode, Dr. Sandeep Thakkar pulls back the curtain on a transformative vision for Parkinson’s and movement disorder care - a vision that challenges the outdated, fragmented healthcare system and reimagines what true, patient-centered excellence should look like. You’ll hear Dr. Thakkar’s bold blueprint for a Center of Excellence: an integrated space where patients access everything from advanced clinical care and cutting-edge research, to on-site physical and speech therapy, nutrition consultations, mental health support, wearables, and even real-time technology solutions - all under one roof. We’ll dive deep into the frustrations patients and their families face navigating the system, the gaps in access and coordination, and why innovation in research and technology can’t wait another decade to reach people who need it most. If you’ve ever wondered what’s possible when we stop settling for the status quo - and how multidisciplinary, tech-enabled, compassionate care could revolutionize the patient experience - this episode is for you. Whether you’re a patient, caregiver, clinician, or someone who believes in progress, you won’t want to miss this inspiring discussion about building a better future for neurological care. Timestamps: 00:00 Integrated Community Parkinson's Care 06:56 Comprehensive Care for Chronic Illnesses 08:24 Healthcare Access Without Limitations 11:09 Accessible Healthcare for All Patients 17:00 "Sensor Technology in Healthcare Monitoring" 18:08 Innovative Clinical Data Collection 23:58 Vision for a 21st Century Healthcare 27:06 Apple Watch Alerts Parkinson's Risk 31:25 Telemedicine Expansion in Healthcare 34:58 Comprehensive Health Clinic Vision 36:32 Expanding Parkinson's Research Network 39:32 Supportive Patient Inspires Podcast Efforts 43:38 Advocate in Healthcare and Research 48:02 "Visionary Healthcare: Building the Future" The Caring Neurologist - Podcast Website - https://thecaringneurologist.com/ Dr. Sandeep Thakkar - LinkedIn - https://www.linkedin.com/in/sandeep-thakkar-do-798a2499/ Dr. Sandeep Thakkar - Clinic - https://ocparkinsons.com/about-mdpds/our-team/dr-thakkar/ TopHealth - https://tophealth.care/ “Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”

Sep 29

Welcome back to The Caring Neurologist! In this energizing episode, lucky number 13, host Dr. Sandeep Thakkar for a deep dive into one of the hottest topics in Parkinson’s care: movement as medicine. Together, they explore how exercise is not just symptom management, but an active tool in reshaping the progression and daily experience of Parkinson’s disease. Dr. Thakkar shares the latest research about the brain-boosting powers of movement, from increasing dopamine and neurotrophic factors to helping regulate mood, sleep, and even digestion. Whether you’re newly diagnosed, a caregiver, or just looking to boost your neural health, you’ll come away with practical tips for building a balanced exercise routine tailored to your stage of Parkinson’s and abilities. Plus, you’ll hear real patient stories that prove it’s never too late to get moving, be it through dance, boxing, or even picking up juggling for the first time. So if you’re curious about whether consistency or intensity matters most, if you want advice on starting safely, or if you’re just seeking a bit of motivation, this episode is packed with insights, humor, and inspiration to help you—and those you love, keep moving forward. 00:00 Healthcare Insights: Focus on Exercise 04:03 Parkinson's: Stretching and Balance Essentials 07:45 Exercise Boosts Brain Health 10:10 Holistic Exercise for Parkinson's Care 12:51 Essential Strength Training with Pilates 17:01 Improving Mobility and Coordination Techniques 21:58 Coordinated Exercise Benefits 23:32 Holistic Exercise for Wellness 26:17 Balanced Daily Exercise Routine 28:59 Parkinson's: High-Intensity Exercise Benefits 34:48 Future Book Plans: Patient Success Stories 38:15 Exercise Revives Sex Life for Seniors 39:02 Maximize Life, Stay Active The Caring Neurologist - Podcast Website - https://thecaringneurologist.com/ Dr. Sandeep Thakkar - LinkedIn - https://www.linkedin.com/in/sandeep-thakkar-do-798a2499/ Dr. Sandeep Thakkar - Clinic - https://ocparkinsons.com/about-mdpds/our-team/dr-thakkar/ TopHealth - https://tophealth.care/ “Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”

Sep 15

Welcome back to The Caring Neurologist! In today’s episode, host Dr. Sandeep Thakkar dives deep into a topic too often overlooked: the unique challenges women face with Parkinson’s disease. Although Parkinson’s is typically studied and portrayed as affecting everyone similarly often depicted as an older man with hallmark symptoms today’s conversation unpacks why that perspective misses the mark for women, and what important gaps remain in our understanding, diagnosis, and treatment of Parkinson’s in female patients. Dr. Thakkar explores how hormones like estrogen impact risk and progression, why women are often diagnosed later than men, and how symptom presentation, side effects, and even clinical research representation differ between the sexes. They also talk candidly about the emotional, psychological, and caregiving burdens unique to women living with Parkinson’s, and discuss actionable steps for doctors, advocates, and patients to move toward more gender-aware care. If you’re curious about the science, the lived experience, and what the future of Parkinson’s care could look like for women, this episode is not to be missed. Let’s get started! 00:00 Parkinson's Misrepresentation in Research 05:49 Gender-Neutral Healthcare Challenges 07:19 Gender Disparities in Health Care 12:08 Estrogen's Protective Role in Parkinson's 16:07 Gender Differences in Disease Progression 17:52 Misdiagnosed Health Struggles 22:18 Women's Health & Environmental Risks 27:00 Gender Differences in Treatment Response 27:52 Addressing Gender Bias in Research 32:29 Personalized Neurotransmitter Therapy for Women 36:01 Gender Differences in Disease Experience 40:01 Exploring Hormonal Therapies' Future 41:01 Anticipating Episode 13 The Caring Neurologist - Podcast Website - https://thecaringneurologist.com/ Dr. Sandeep Thakkar - LinkedIn - https://www.linkedin.com/in/sandeep-thakkar-do-798a2499/ Dr. Sandeep Thakkar - Clinic - https://ocparkinsons.com/about-mdpds/our-team/dr-thakkar/ TopHealth - https://tophealth.care/ “Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”

Sep 3

Welcome back to “The Caring Neurologist,” where we dive deep into the mysteries of the brain and bring practical, real-life advice straight from the clinic. In this illuminating episode, Dr. Sandeep Thakkar takes on one of the most essential and underestimated pillars of our health: sleep. Whether you’re living with Parkinson’s or just trying to get a better night’s rest, you’ll want to tune in as our hosts uncover the hidden connections between Parkinson’s disease and sleep disorders. They discuss how sleep struggles can be some of the earliest warning signs of neurological issues sometimes appearing years before classic symptoms do, why sleep disturbances are more than just an inconvenience, and how they affect everything from motor function to mood and memory. Dr. Thakkar and Ursula break down the science behind the stages of sleep, explain what’s really going on when you act out your dreams, and share actionable tips for getting better rest, plus a few surprising truths about so-called sleep “remedies” we’ve heard for generations. They also answer listener questions about shifting sleep habits, choosing the right wearable tech, and when it’s time to see a specialist. This episode isn’t just for those affected by Parkinson’s, it’s a wake-up call for anyone striving for better brain health. So grab your favorite non-dairy drink, get comfortable, and join us for an eye-opening discussion that just might change the way you sleep tonight. 00:00 "Sleep's Fundamental Importance" 06:06 "Stages of Sleep Explained" 09:51 Parkinson's: Acting Out Dreams 11:53 "Sleep Disruptions and PTSD Patterns" 14:05 Medication Side Effects: Insomnia and Daytime Sleepiness 19:38 Dopamine's Impact on Sleep and Cognition 22:53 Sleep Deprivation and Health Impact 26:12 Discussing Vivid Dream Causes 28:47 Improve Sleep with Daily Habits 31:08 Parkinson's and Sleep Disruption 34:06 "Sugar's Impact on Sensitive Brains" 39:36 Hopeful Advancements in Sleep Therapy 40:40 Adaptive DBS and New Parkinson’s Treatments 44:13 "See Neurologist for Movement Symptoms" 46:51 Future Episode on Sleep? The Caring Neurologist - Podcast Website - https://thecaringneurologist.com/ Dr. Sandeep Thakkar - LinkedIn - https://www.linkedin.com/in/sandeep-thakkar-do-798a2499/ Dr. Sandeep Thakkar - Clinic - https://ocparkinsons.com/about-mdpds/our-team/dr-thakkar/ TopHealth - https://tophealth.care/ “Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”

Aug 6

Welcome back to The Caring Neurologist ! In this milestone 10th episode, “The Future of Genetic Therapy in Movement Disorders,” the ever-insightful Dr. Sandeep Thakkar unravels the science and hope behind gene therapy for Parkinson’s disease and beyond. They break down what gene therapy really means, going beyond the headlines and “science fiction” buzzwords like CRISPR to explain how this groundbreaking approach aims to address the very root causes of movement disorders. Dr. Thakkar shares the latest updates on clinical trials for therapies targeting genetic mutations like GBA1, and discusses how viral delivery systems and gene editing are shaping the next wave of Parkinson’s treatments. The conversation moves from technical breakthroughs to bigger questions about safety, personalized medicine, real-world challenges, and the immense hope these advances offer for patients and families. Whether you’re living with Parkinson’s, care for someone who is, or are just fascinated by the future of medicine, this episode will leave you feeling both grounded and inspired. Stay tuned for an episode that’s as informative as it is hopeful! 00:00 Gene Therapy Advances 03:28 Gene Therapy for Parkinson's 07:24 Gene Editing: CRISPR Explored 12:43 GBA1 Mutation in Parkinson's Disease 16:15 Gene Therapy: A Parkinson's Update 17:09 Revolutionizing Care in Neurology 21:26 Gene Therapy Advancements in Huntington's Disease 26:17 Gene Therapy Delivery Challenges 29:43 Genetic Insights in Parkinson's Prevention 33:23 Understanding Future Changes in Gene Therapy 36:16 Balance Excitement and Challenges 37:37 Ozzy Osbourne's Impactful Legacy The Caring Neurologist - Podcast Website - https://thecaringneurologist.com/ Dr. Sandeep Thakkar - LinkedIn - https://www.linkedin.com/in/sandeep-thakkar-do-798a2499/ Dr. Sandeep Thakkar - Clinic - https://ocparkinsons.com/about-mdpds/our-team/dr-thakkar/ TopHealth - https://tophealth.care/ “Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”

Jul 17

Welcome to another episode of The Caring Neurologist ! In today’s insightful conversation, Dr. Sandeep Thakkar's talks about what Diet and Toxins Reveal About Brain Health. As one of the most-heard video podcasts in neurology, this episode tackles the crucial, and often misunderstood links between nutrition, environmental toxins, and brain health, especially for those living with Parkinson’s and movement disorders. Dr. Thakkar explores how what we eat truly acts as medicine for the mind, breaking down the science behind everyday foods, healthy eating patterns, and why your grocery list matters more than ever. They discuss the impact of processed foods, why the “Mediterranean” and “MIND” diets win out, and offer practical advice for anyone feeling overwhelmed by conflicting dietary guidance and environmental health news. Whether you’re looking for clear advice on what to eat, how to minimize exposure to harmful substances, or realistic steps to improve your nutrition, this episode serves as a friendly guide to boosting your brain’s health one bite at a time. Grab your favorite snack (just maybe skip the breakfast pizza), and join us for a relatable, evidence-based conversation designed to empower you on your journey to better brain health! 00:00 "Food as Fuel and Medicine" 05:00 Supporting Brain Health with Nutrition 08:39 Small Changes for Lasting Success 12:39 "Foods Harmful to Brain Health" 16:29 Pesticides, Farming, and Parkinson's Link 19:23 Water Contamination Awareness & Action 23:22 Choosing Clean Over Costly Organic 26:36 Consistent Healthy Eating Mindset 29:53 Sweets Worsen Parkinson's Symptoms 32:26 Enhanced Food Label Clarity 36:52 "Boost Health with Habits" 38:27 Artificial Sweeteners and Health Concerns The Caring Neurologist - Podcast Website - https://thecaringneurologist.com/ Dr. Sandeep Thakkar - LinkedIn - https://www.linkedin.com/in/sandeep-thakkar-do-798a2499/ Dr. Sandeep Thakkar - Clinic - https://ocparkinsons.com/about-mdpds/our-team/dr-thakkar/ TopHealth - https://tophealth.care/ “Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”