The New Face of Menopause: Hormones, Supplements & GLP-1 Therapy with Jackie Giannelli | Ep. 111

Menopause is no longer a silent struggle. From “millennipause” to cutting-edge treatments like GLP-1s, today’s conversation with Jackie Giannelli, a board-certified family nurse practitioner specializing in women's health with extensive expertise in hormonal health, menopause, women's sexual health, and urogynecology, dives into the evolving landscape of perimenopause and menopause care. We explore the shifting attitudes around hormone replacement therapy, the rise of millennials entering perimenopause, and why lifestyle, supplements, and community matter just as much as medical interventions. Jackie also breaks down how GLP-1 medications may become a new arm of menopause treatment — while highlighting their potential impact on sexual health. Whether you’re curious about natural options, considering hormone therapy, or just beginning your perimenopause journey, this episode offers clarity, science-backed insights, and compassion for women navigating this complex phase of life. Timestamps: 0:00 – Welcome & Introduction to Jackie Giannelli 1:15 – What is “Millennipause”? 4:12 – How millennials are approaching perimenopause differently 6:45 – Hormone hesitancy is fading: why women want bioidenticals now 9:50 – Non-hormonal treatments: supplements that actually work 13:30 – Lifestyle shifts that make a difference in perimenopause 16:45 – GLP-1 medications and their surprising potential in menopause care 21:05 – The hidden side effects of GLP-1s on sexual health 23:18 – The power of community and women supporting women 25:10 – Jackie’s definition of sex & closing thoughts Want a deeper look? Watch the full episode on YouTube for a more visual experience of today’s discussion. This episode is best enjoyed on video—don’t miss out! Karen Bigman , a Sexual Health Alliance Certified Sex Educator, Life, and Menopause Coach, tackles the often-taboo subject of sexuality with a straightforward and candid approach. We explore the intricacies of sex during perimenopause, post-menopause, and andropause, offering insights and support for all those experiencing these transformative phases. This podcast is not intended to give medical advice. Karen Bigman is not a medical professional. For any medical questions or issues, please visit your licensed medical provider. Looking for some fresh perspective on sex in midlife? You can find me here: Email: karen@taboototruth.com Website: https://www.taboototruth.com/ Instagram: https://www.instagram.com/taboototruth YouTube: https://www.youtube.com/@taboototruthpodcast Karen Bigman, a Sexual Health Alliance Certified Sex Educator, Life, and Menopause Coach, tackles the often-taboo subject of sexuality with a straightforward and candid approach. We explore the intricacies of sex during perimenopause, post-menopause, and andropause, offering insights and support for all those experiencing these transformative phases. This podcast is not intended to give medical advice. Karen Bigman is not a medical professional. For any medical questions or issues, please visit your licensed medical provider. Looking for some fresh perspective on sex in midlife? You can find me here: Email: karen@taboototruth.com Website: https://www.taboototruth.com/ Instagram: https://www.instagram.com/taboototruth YouTube: https://www.youtube.com/@taboototruthpodcast About the Guest: Jackie Giannelli is a board-certified family nurse practitioner specializing in women's health with extensive expertise in hormonal health, menopause, women's sexual health, and urogynecology. Jackie is a Menopause Society-certified practitioner, and an active member of the International Society for the Study of Women's Sexual Health. She trained and honed her expertise in this niche field at the largest freestanding women’s sexual health clinic in the country, Maze Women’s Health. Previously, Jackie has served as the founding nurse practitioner and Director of Clinical Practice at Elektra Health , a digital women’s health company on a mission to smash the menopause taboo. She also spent time as an Operator-in-Residence at 25m Health , a health-tech venture platform incubating new companies and investing in breakout startups. She advises and consults regularly in the digital health and startup space, and often mentors clinicians who are looking to pivot from the bedside into a non-traditional clinical role. She also continues to practice bedside medicine and is taking new patients as the Director of Women’s Sexual Health at Anna Barbieri, MD in NYC. Jackie is passionate about women’s health literacy and using technology to expand access to care, as well innovation in clinical strategy and private practice enablement. Jackie aims to democratize access to evidence-based midlife wellness education using her social media platform , through her newsletter In the Saddle , her digital clinical frameworks and as the co-host of the WellKept podcast . Jackie earned her nursing degrees at New York University and San Francisco State University and a B.A. in Health Studies from Georgetown University. Her work has been featured in Well+Good, PopSugar, and Everyday Health. She is a sought-after national speaker and educator in the field of women’s health. She lives in CT with her husband and two tween children but will never tire of trips to NYC for theater, culture, shopping and endless inspiration. Connect with Jackie Giannelli: Instagram: https://www.instagram.com/jackie_giannellifnp/ LinkedIn: https://www.linkedin.com/in/jacqueline-giannelli-rn-msn-fnp-bc-ncmp/ Podcast: https://open.spotify.com/show/6eQRSsPNEE9R39Ah5182Yk?si=dfc033ca2bd6488d Take control of your pleasure with my Pleasure Playbook , filled with tips to help you connect with your body and enhance intimacy. Download it now at www.taboototruth.com/pleasureplaybook . Take control of your pleasure with my Pleasure Playbook, filled with tips to help you connect with your body and enhance intimacy. Download it now at www.taboototruth.com/pleasureplaybook .