Gene Hunting with o1-pro: Reasoning about Rare Diseases with ChatGPT Pro Grantee Dr. Catherine Brownstein

Nathan explores the cutting-edge intersection of AI and rare disease research with Dr. Catherine Brownstein of Boston Children's Hospital and Harvard Medical School. In this episode of The Cognitive Revolution, we dive into how frontier AI models are revolutionizing the diagnosis of rare diseases. Join us for an insightful conversation with a ChatGPT Pro grant winner who's pioneering the use of AI to help patients find answers faster. Help shape our show by taking our quick listener survey at https://bit.ly/TurpentinePulse Check out Modern Relationships, where Erik Torenberg interviews tech power couples and leading thinkers to explore how ambitious people actually make partnerships work. This season's guests include: Delian Asparouhov & Nadia Asparouhova, Kristen Berman & Phil Levin, Rob Henderson, and Liv Boeree & Igor Kurganov. Apple: https://podcasts.apple.com/us/podcast/id1786227593 Spotify: https://open.spotify.com/show/5hJzs0gDg6lRT6r10mdpVg YouTube: https://www.youtube.com/@ModernRelationshipsPod SPONSORS: Oracle Cloud Infrastructure (OCI): Oracle's next-generation cloud platform delivers blazing-fast AI and ML performance with 50% less for compute and 80% less for outbound networking compared to other cloud providers. OCI powers industry leaders like Vodafone and Thomson Reuters with secure infrastructure and application development capabilities. New U.S. customers can get their cloud bill cut in half by switching to OCI before March 31, 2024 at https://oracle.com/cognitive NetSuite: Over 41,000 businesses trust NetSuite by Oracle, the #1 cloud ERP, to future-proof their operations. With a unified platform for accounting, financial management, inventory, and HR, NetSuite provides real-time insights and forecasting to help you make quick, informed decisions. Whether you're earning millions or hundreds of millions, NetSuite empowers you to tackle challenges and seize opportunities. Download the free CFO's guide to AI and machine learning at https://netsuite.com/cognitive Shopify: Dreaming of starting your own business? Shopify makes it easier than ever. With customizable templates, shoppable social media posts, and their new AI sidekick, Shopify Magic, you can focus on creating great products while delegating the rest. Manage everything from shipping to payments in one place. Start your journey with a $1/month trial at https://shopify.com/cognitive and turn your 2025 dreams into reality. Vanta: Vanta simplifies security and compliance for businesses of all sizes. Automate compliance across 35+ frameworks like SOC 2 and ISO 27001, streamline security workflows, and complete questionnaires up to 5x faster. Trusted by over 9,000 companies, Vanta helps you manage risk and prove security in real time. Get $1,000 off at https://vanta.com/revolution CHAPTERS: (00:00:00) Teaser (00:00:56) About the Episode (00:04:45) Rare Diseases Common (00:06:48) Patient Journey (00:12:57) Genome Sequencing (00:19:39) Sponsors: Oracle Cloud Infrastructure (OCI) | NetSuite (00:22:19) Diagnosis Process (00:30:50) Data Pipelines (00:35:51) Sponsors: Shopify | Vanta (00:39:07) Interaction Graphs (00:42:18) Data Accessibility (00:43:42) AI in Pipelines (00:45:40) LLM Impact (00:48:40) Anomaly Detection (00:52:07) Data Sharing (00:58:49) Data Reform (01:02:41) AI's Potential (01:04:30) AI Applications (01:06:57) Prompt Engineering (01:14:51) Model Comparison (01:19:16) Prompting Insights (01:22:14) Move 37 Analogy (01:24:34) Future Potential (01:29:27) Future Experience (01:32:39) Outro SOCIAL LINKS: Website: https://www.cognitiverevolution.ai Twitter (Podcast): https://x.com/cogrev_podcast Twitter (Nathan): https://x.com/labenz LinkedIn: https://www.linkedin.com/in/nathanlabenz/ Youtube: https://www.youtube.com/@CognitiveRevolutionPodcast Apple: https://podcasts.apple.com/de/podcast/the-cognitive-revolution-ai-builders-researchers-and/id1669813431 Spotify: https://open.spotify.com/show/6yHyok3M3BjqzR0VB5MSyk