Journal Club: Exploring Immune Response to Diet: Vegan vs Ketogenic Ep. 38

In this episode of The Metabolic Link, Victoria Field, Dr. Dominic D'Agostino, and Dr. Angela Poff dive into a fascinating new paper that compares the metabolic and immune impacts of ketogenic and vegan diets in humans. The study, titled “Differential Peripheral Immune Signatures Elicited by Vegan Versus Ketogenic Diets in Humans” takes a deep dive into the multi-omic effects of these two very different dietary approaches. The researchers found that just two weeks on a ketogenic diet significantly enhanced markers of adaptive immunity, while the vegan diet was associated with increased innate immune function. The hosts unpack these findings, discussing the potential mechanisms behind the divergent immune signatures, the limitations of the short-term study design, and the need for further research. They also highlight the importance of carefully standardizing the macronutrient and micronutrient compositions of the dietary interventions to isolate the key drivers of the observed changes. Overall, this episode provides a thought-provoking look at the profound impacts that diet can have on the functioning of our immune system, setting the stage for future studies exploring the therapeutic potential of nutritional approaches. This episode is sponsored by Genova Diagnostics. Genova has been researching and refining precision health testing for decades. It's that experience that has allowed them to create comprehensive assessments that shed light on your individual health status and make recommendations for changes that will bring your wellness into focus. Genova Connect, powered by Genova Diagnostics, offers easy access to advanced lab tests, covering key health areas like metabolic health, nutrition, gut health, immune function, and hormones. Through Genova Connect, anyone can gain insights into their health and find ways to improve their well-being. Learn more at https://gdx.net/themetaboliclink As mentioned in the introduction, you can watch the free virtual masterclass co-hosted Genova Diagnostics and Metabolic Health Summit showcasing some of the world-leading experts in metabolic health here . In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in! You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel ! Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.