Preserving Muscle on GLP-1 Weight Loss Medications (or Rapid Fat Loss) | Ep 308

Get your free 15-minute Rapid Nutrition Assessment to identify your biggest nutrition challenge and get a personalized action plan to optimize your approach, whether you're considering GLP-1s, currently using them, or transitioning off (or go to witsandweights.com and click "Free Nutrition Audit") -- Millions of people are experiencing dramatic weight loss results with GLP-1 medications like Ozempic, Wegovy, and Mounjaro, but there's a catch that many doctors aren't discussing: without the right approach, up to 40% of that weight loss could be coming from muscle, not fat. This episode gives you a blueprint for maximizing the benefits of these medications while protecting your metabolism, strength, and long-term results. Today I'm sharing practical, evidence-based strategies to preserve muscle while maximizing fat loss on these powerful appesite-suppressing medications, including how to adjust your nutrition, training, and lifestyle to maintain those results even after you stop. Main Takeaways: GLP-1 medications aid weight loss primarily through appetite suppression Muscle loss isn't caused by the medications but by rapid weight loss without intervention Resistance training and sufficient protein intake are non-negotiable for preserving muscle mass Plan your transition off medication well in advance with a strategic approach Episode Resources: Try MacroFactor for free with code WITSANDWEIGHTS Timestamps: 0:01 - Understanding GLP-1 medications and body composition 6:29 - Protein and nutrition strategies 10:14 - Micronutrients and tracking calories 12:10 - Why resistance training is essential 16:02 - Managing energy levels and strength training 16:47 - Planning for reducing or coming off GLP-1 medications 21:56 - Body recomposition Support the show 📱 Get Fitness Lab - Philip’s science-based AI app for fat loss, muscle building, and strength training for people over 40. It adapts to your nutrition, recovery, and training to improve body composition without guesswork. 🎓 Try Physique University - Evidence-based nutrition coaching and strength training to help you lose fat, build muscle, and master your metabolism with support and accountability (free custom nutrition plan with code FREEPLAN ). 👥 Join our Facebook community - Free fat loss, muscle building, and body recomposition strategies for adults over 40 who want practical, science-backed fitness guidance. 👋 Ask a question or find Philip Pape on Instagram