About this episode
In today's episode of The Root Cause Medicine Podcast, Dr. Yael Joffe joins Dr. Kate Kresge to discuss her remarkable journey from architecture student to nutrigenomics pioneer, driven by a personal loss that left her searching for answers. You’ll hear us discuss: The role of genetic insights in supporting personalized wellness approaches 3X4 Genetics innovative approach to genetic testing The challenges of bringing genetics into clinical practice How AI might reshape the field Dr. Joffe is a pioneering figure in nutrigenomics and the founder of 3X4 Genetics. Originally from South Africa, she began her career studying architecture before pivoting to dietetics following her grandmother's battle with cancer. Driven to understand the intersection of genetics and nutrition more deeply, she pursued a PhD in genetics while working full-time. Throughout her career, Dr. Joffe has been instrumental in developing nutrigenomic testing methodologies, including the Darwin methodology used by 3X4 Genetics to analyze genetic markers for potential insights in personalized wellness. Additionally, Dr. Joffe is the author of The Power Of Genetics. Labs Mentioned: 3X4 Genetics Test Detoxification Biomarkers DNA Life Tests Guest Details: Dr. Yael Joffe’s Website , LinkedIn , Instagram , X , Book 3X4 Genetics’ Website Manuka Science Website Rupa Health Details: Rupa Health's Website , LinkedIn , Instagram , YouTube Rupa Health Reference Guide & Magazine Dr. Kate Kresge ’s Website , LinkedIn , Instagram , Youtube & Twitter Dr. Kate Kresge on Podcast Timestamps 03:07 - From Art to Science 16:24 - Why PhDs Deserve More Credit 33:56 - The Birth of 3X4 Genetics 47:21 - AI’s Role in Genetics, Healthcare, and Research 53:55 - How 3X4 Chooses the Right Genes 01:05:27 - Why Every Clinician Should Consider Genetic Testing 01:08:14 - Clinical Application: A Detoxification Case Study 01:11:16 - The Future of Genetics