Why Collagen Doesn’t Work Without Vitamin C + Other Supplement Truths

What if your collagen cream isn’t working, because your skin doesn’t have the raw materials to use it? In this episode of Biohacking Beauty we reveal the missing half of most people’s skincare: the internal protocol. From vitamin C as a collagen cofactor (“10x harder for your skin to build collagen without it”) to the role of omega-3s in plumping skin from the inside out, this episode lays out a step-by-step supplement strategy for real skin longevity. We break down why oral hyaluronic acid outperforms topical forms in clinical trials, why senescent cells are not the root cause of aging (just a symptom), and how bioactives like NMN, ergothioneine, and astaxanthin actually get expressed in the skin, unlike most topicals. We also discuss trends like matcha and how it outperforms coffee for skin health, and why oral senolytics like fisetin help eliminate zombie cells that drive inflammation and visible aging. You don't want to miss this one! What's Discussed: (00:39) Why Supplements Matter More Than Serums (03:38) The Foundational Skin Stack: C, D, E, Omegas, Collagen, HA (19:04) Mid-Tier Bioactives: CoQ10, Curcumin, EGCG, Astaxanthin (34:33) Advanced Longevity: NMN, Fisetin, Spermidine, Sulforaphane (43:05) Metabolomics Testing + Personalized Skin Protocols (52:46) Final Takeaways: Building a Skin Longevity Regimen Find more from Young Goose: The YouTH Firming Body Cream: Smoother arms, firmer thighs, tighter skin, powered by NAD+ and spermidine. Your body’s anti-aging breakthrough → Body Cream Spermidine Serums: Fewer wrinkles. More collagen. Real skin renewal at the cellular level. The serum your face has been waiting for → Spermidine Serums Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/ Instagram: @young_goose_skincare