Understanding Cholesterol Dynamics and Metabolic Health with Dr. Nick Norwitz

In this episode, explore the fascinating world of cholesterol dynamics with Dr. Nick Norwitz as he challenges conventional wisdom. Discover the significance of understanding cholesterol risk profiles, particularly in lean mass hyper-responders on a ketogenic diet. Dive into Dr. Norwitz's bold "Oreo vs. Statin" study, which uncovers surprising insights about cholesterol management. Learn how this experiment highlights the need to reassess traditional approaches to heart health. Gain valuable knowledge on why LDL cholesterol should not be the sole focus when evaluating cardiovascular risk. Understand the importance of a holistic view that considers individual metabolic health. In This Episode: 00:00 Understanding LDL and Cardiovascular Risk 04:08 Episode Overview: Oreo Cookie Study 07:24 Interview with Dr. Nicholas Norowitz 08:20 The Oreo Cookie Experiment 15:59 Exploring the Lean Mass Hyper Responder Phenomenon 34:43 Understanding VLDL and Triglyceride Metabolism 35:28 The Triad: LDL, HDL, and Triglycerides 36:36 Exploring the Lipid Energy Model 37:30 Insulin's Role in Fat Metabolism 38:22 Clinical Data and Metabolic Profiles 41:20 The Controversy of LDL Particles 46:26 The Lean Mass Hyper Responder Phenotype 52:49 Personal Journey with Ketogenic Diet 58:01 Side Effects of Statin Drugs 01:02:20 Satiety Per Calorie and Marketing Tactics 01:07:47 Conclusion and Final Thoughts This episode is sponsored by Paleo Valley and their Organic Supergreens powder, a product I love for its high chlorophyll content, which supports blood purification, detoxification, and mitochondrial health. Packed with digestive-supportive superfoods like ginger, lemon, and beet, it's free from cereal grasses, making it gentle on the gut, especially for those with chronic inflammation. I mix a scoop in water daily, usually after lunch, for an energy boost and mental clarity. You can save 15% on any Paleo Valley product, including their Organic Supergreens, by visiting paleovalley.com/jockers This podcast is sponsored by ShopC60.com. C60 is a powerful, Nobel Prize-winning antioxidant that helps to optimize mitochondrial function, fights inflammation, and neutralizes toxic free radicals! I'm a big fan of using C60 in conjunction with your keto and intermittent fasting lifestyle to support your immune system, help your body detox, and increase energy and mental clarity. My favorite C60 products for Keto & IF lifestyles include C60 Purple Power in Organic MCT Coconut Oil (you can add this to your coffee) and their delicious Sugar-Free C60 Gummies (made with allulose and monk fruit)! If you are over the age of 40, and you'd like to kick fatigue and brain fog to the curb this year, visit shopc60.com and use the coupon code "JOCKERS" for 15% OFF and start taking back control over your health today! "The physiology behind lean mass hyper-responders is an incredible natural experiment, a gift to science." -Dr. Nick Norwitz Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio Resources: Visit https://shopc60.com/jockers – Use code "JOCKERS" to get 15% off! Paleovalley's Supergreens - visit paleovalley.com/jockers Oreo Study - https://pubmed.ncbi.nlm.nih.gov/38276308/ Don't be Fooled! A Lesson in Unmasking Pseudoscience - https://www.youtube.com/watch?v=1IWCmFgThQA Connect with Dr. Nick Norwitz: Twitter: https://x.com/nicknorwitz Instagram: https://www.instagram.com/nicknorwitz/ YouTube: https://www.youtube.com/channel/UCLTZUJSEulehPtF_ytFiU_A?sub_confirmation=1 Newsletter: https://staycuriousmetabolism.substack.com/ Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https://www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/