#095 - Jonathan Bailor: Body Weight Setpoint, Burning Calories, Food Quality, Obesity & Diabetes Epidemic, Brain Inflammation, Hormonal Dysregulation & Gut Dysbiosis, The SANE Solution, And More!

GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/setpoint 1:55 - Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon 2:05 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome! 6:40 - Jonathan's Personal History 11:35 - Why Do People Gain Or Lose Weight? 13:10 - The Global Economic Impact Of Diabetes 14:50 - What Happens With Calories That We Eat? 16:45 - The Calorie Is A Measure Of Energy Alone 18:00 - Why Does The Body Burn Or Store Calories? 19:50 - Dietary Induced Thermogenesis 20:00 - N.E.A.T. (Non-Exercise Activity Thermogenesis) 23:20 - Perceived Rate Of Exertion 24:20 - Eat Less, Move Less 24:30 - What Is The Stress Response To A Crash Diet? 25:10 - Long Term Outcomes Of Crash Dieting 26:15 - Yo-Yo Dieting And The Extracellular Matrix 27:00 - Defining The "Set Point" 29:55 - How Do We Get Our Set Point? How Does It Change? 33:00 - Obesity As A Disease State 34:00 - The Quality Of The Food We Eat 35:00 - The Overconsumption Of Food 36:40 - Hormone "Clogging" 39:35 - Parabiotic Studies 40:45 - The Communication Between Brain, Gut, And Hormones 43:40 - The Genetic Component 47;55 - The Pervasive Shame In Being "Over-Fat" In Society 48:30 - SANESolution 50:25 - Evaluating Foods On A Spectrum For Optimal Health 52:10 - The SANE Food Groups 55:30 - What About Lower Fat Or Lower Carb? 57:05 - Metabolic Conditioning 59:10 - The Randall Cycle 59:25 - The Myth Of Exercise 1:02:50 - Mechanical Removal Of Fat Cells