About this episode
Chapters 00:00 Introduction to Circadian Rhythms and Skeletal Muscle 02:52 Understanding the Circadian Clock 06:12 Dysregulation of Circadian Rhythms 09:06 Impact of Inflammation on Circadian Clocks 12:00 Peripheral Clocks and Their Independence 15:06 Exercise Timing and Performance 18:06 Feeding Patterns and Circadian Rhythms 21:00 Chronotypes and Individual Differences 23:59 Caffeine and Its Effects on the Clock 27:02 Adaptation of Circadian Clocks in Extreme Conditions 29:58 Alcohol's Impact on Circadian Function 31:01 The Impact of Circadian Clocks on Muscle and Tendon Health 36:34 Aging and Its Effects on Circadian Rhythms 40:47 Injury and Circadian Clocks: Understanding the Connection 43:10 The Role of Nutrition and Feeding Patterns 48:29 Circadian Disruption and Metabolic Health 51:50 Practical Applications for Maintaining Healthy Clocks Takeaways Circadian clocks are molecular timers found in every cell. The clock regulates metabolism and gene expression based on time of day. Dysregulation can lead to health issues like increased glucose levels. Peripheral clocks can operate independently of the central clock. Exercise timing can enhance performance and adaptation. Feeding patterns should align with activity for optimal health. Chronotype influences individual preferences for sleep and activity. Caffeine affects the sympathetic nervous system but doesn't phase shift the clock. Alcohol can disrupt circadian function and health. Adaptation of clocks can occur even in extreme light conditions. Circadian clocks significantly influence muscle and tendon health. Disruption of circadian rhythms can lead to metabolic issues. Aging affects the ability of circadian clocks to regulate gene expression. Inactivity does not stop circadian clocks, but it affects their function. Nutrition timing is crucial for maintaining healthy circadian rhythms. Exercise can enhance the function of circadian clocks in muscles. Understanding the communication between muscle and tendon is vital for rehabilitation. Time-restricted feeding may extend lifespan and improve health. Research on circadian rhythms can inform strategies for injury recovery. Maintaining a consistent activity and feeding schedule supports clock health. Karyn's profile: https://physiology.med.ufl.edu/profile/esser-karyn/ Karyn's Linkedin: https://www.linkedin.com/in/karyn-esser-a187333 Notes: https://jackedathlete.com/podcast-129-circadian-rhythms-with-karyn-esser/