#123 – Manolis Kellis: Origin of Life, Humans, Ideas, Suffering, and Happiness

Manolis Kellis is a professor at MIT and head of the MIT Computational Biology Group. Please check out our sponsors to get a discount and to support this podcast: – Public Goods : https://publicgoods.com/lex and use code LEX – Magic Spoon : https://magicspoon.com/lex link & using code LEX at checkout – ExpressVPN : https://www.expressvpn.com/lexpod Lex Fridman Podcast survey mentioned in the intro: https://www.surveygizmo.com/s3/5833660/Lex-Fridman-Podcast-Survey If you would like to get more information about this podcast go to https://lexfridman.com/podcast or connect with @lexfridman on Twitter , LinkedIn , Facebook , Medium , or YouTube where you can watch the video versions of these conversations. If you enjoy the podcast, please rate it 5 stars on Apple Podcasts , follow on Spotify , or support it on Patreon . Here’s the outline of the episode. On some podcast players you should be able to click the timestamp to jump to that time. OUTLINE: 00:00 – Introduction 06:20 – Epigenome 10:28 – Evolution 15:26 – Neanderthals 27:15 – Origin of life on Earth 43:44 – Life is a fight against physics 49:56 – Life as a set of transformations 51:35 – Time scales 1:00:31 – Transformations of ideas in human civilization 1:05:19 – Life is more than a rat race 1:13:18 – Life sucks sometimes and that’s okay 1:30:16 – Getting older 1:36:21 – The best of MIT 1:49:01 – Poem 1: The Snow 2:01:52 – Love 2:06:16 – Poem 2: The Tide Waters