How Relationships Heal Inflammation, Trauma, and Your Nervous System

Relationships have the power to change lives in ways both visible and hidden. Deep, supportive bonds can quiet inflammation in the body, protect against disease, and anchor people through decades of triumphs and trials. Communities that come together—whether in small groups at a church or around a shared health goal—often achieve far more than individuals working alone, sometimes transforming their health on a massive scale. Lifelong friends celebrate each other’s victories without jealousy, weather hardship side by side, and dare to speak difficult truths even at the risk of the relationship. Yet, many remain in unfulfilling connections out of fear of loneliness, forgetting that genuine, vulnerable connection is not just emotionally nourishing—it is essential to human health and resilience. In this episode, I talk with Simon Sinek, Esther Perel, and Angelika Alana about how relationships are vital not just for emotional health, but for physical wellbeing and can be a great source of growth and healing. Simon is a spark that ignites passion and ideas. He envisions a world where people wake up inspired, feel safe, and end their day fulfilled. As an unshakeable optimist and trained ethnographer, Simon is fascinated by people and organizations that make a lasting impact. He has discovered remarkable patterns in how they think, act, and communicate, revealing how people perform at their best. Simon is widely known for his TED Talk on "WHY" and his viral video on millennials in the workplace. Through bestselling books like Start with WHY and his podcast A Bit of Optimism , he continues to inspire. Founder of The Optimism Company and Optimism Press, Simon shares innovative views on leadership, attracting international attention. He also works with the U.S. government, the RAND Corporation, and in 2021, founded The Curve to reform modern policing, advancing justice with dignity, equity, and fairness. Psychotherapist and New York Times bestselling author Esther Perel is recognized as one of today’s most insightful and original voices on modern relationships. Fluent in nine languages, she helms a therapy practice in New York City and serves as an organizational consultant for Fortune 500 companies around the world. Her celebrated TED Talks have garnered more than 30 million views and her bestselling books, Mating in Captivity and The State of Affairs , are global phenomena translated into nearly 30 languages. Esther is also an executive producer and host of the popular podcasts Where Should We Begin? and How’s Work? Her latest project is Where Should We Begin - A Game of Stories with Esther Perel. Angelika Alana is the founder and CEO of the Somatic Healing Institute. She has been featured in Vanity Fair , Well+Good , and Modern Luxury. She certifies coaches and facilitators in her transformational body-based healing method. She has traveled and studied extensively in Indonesia, Brazil, Australia, and the UK, and is a massive foodie with her husband Patrick Drake, co-founder of Hello Fresh. This episode is brought to you by BIOptimizers. Head to bioptimizers.com/hyman and use code HYMAN to save 15%. Full-length episodes can be found here: Simon Sinek on the Power of Relationships for Longevity How To Have Successful Relationships How To Move From Toxic Relationships And Sex To Healing Relationships And Sex