647: Hormone Optimization Therapy (HOT) Isn't Your Mom's HRT + It's One Of The Best Strategies For Longevity with Dr. Amy Killen

The research is so clear… if you want to speed up your biological age, don’t use hormones. You can be so healthy and dialed in with your habits, but even that won’t stop your hormones from inevitably plummeting in midlife. That’s why Dr. Amy Killen joins the show to dive into the realities of women’s health in midlife and how hormone replacement can be a game-changer . This conversation sheds light on what’s really happening inside your body in midlife— and what you can do about it! Dr. Amy breaks down how hormone replacement therapy (HRT), targeted supplements, and strategic lab testing can be huge for your energy, cognition, and longevity. We’ll also cover the lifestyle changes that truly move the needle in midlife, and how to stay proactive instead of stuck in “default mode.” If you’ve ever felt like you’re doing everything right but still struggling, this episode will make you feel seen and offer real solutions. It’s time to feel inspired, empowered, informed, and ready to take ownership of your midlife health journey! Amy Killen, M.D. Dr. Amy Killen is a leading physician in regenerative and hormone optimization medicine, specializing in women's health. As an emergency physician turned longevity specialist, she combines treatments like stem cell therapy, hormone optimization, and peptides with practical lifestyle wisdom. She’s the Chief Medical Officer of Humanaut Health and founder of the Human Optimization Project. IN THIS EPISODE Why estrogen MATTERS Prioritizing movement for longevity Day-to-day non-negotiables that move the needle Supplements for energy and mitochondrial health The link between HRT and longevity in women Addressing common myths around perimenopause and HRT The importance of functional lab tests and screenings QUOTES “You could be so dialed in with your lifestyle, with your mindset, with your supplements, your everything, and you'll still have declining estrogen and progesterone.” “Start working on the hormones. It can help with the drive to do the lifestyle things. And I've seen that a lot.” “We can increase human lifespan in women with these hormones and they're very inexpensive, yet less than 5% of women have access [to them].” RESOURCES MENTIONED Dr. Amy’s Website *Join Dr. Amy’s Newsletter here and get her FREE Supplement Guide! Dr. Amy’s Instagram Dr. Amy’s Facebook Dr. Amy’s Female-focused supplement product: HOP Box Get your magnesium at drmariza.com/magnesium with code PODCAST . RELATED EPISODES #605: Breaking the HRT Confusion: The Truth Behind Hormone Replacement Therapy for Perimenopausal Women with Karen Martel 579: Hormone Replacement Options and Hormone Testing for Women in Midlife + Self Advocacy for Optimal Health with Esther Blum #576: How to Build Bone, Muscle, Tendon, and Metabolic Resilience in Perimenopause and Menopause with Dr. Vonda Wright #557: What Every Women Needs to Know About Hormone Replacement In Their 40s and Beyond with Felice Gersh