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Author: Erik Verzemnieks, MD Educational Pearls: Otic (ear) specific antibiotic drops can be expensive Opthalmic (eye) versions are basically identical and can be used as an affordable substitute as many are on the $4 drug lists But don't do the reverse (don't use ear drops on the eye) Use caution when administering aminoglycoside if tympanic membrane rupture is present References https://tgtfiles.target.com/pharmacy/WCMP02-032536_RxGenericsList_NM7.pdf http://i.walmart.com/i/if/hmp/fusion/four_dollar_drug_list.pdf https://www.uptodate.com/contents/external-otitis-treatment