#253 COVID-19 Vaccines with Dr Monica Gandhi

Answer all your burning questions (and your patients’ burning questions) about the different COVID-19 vaccines currently authorized in the US. Infectious diseases / HIV expert, Dr Monica Gandhi @MonicaGandhi9 (UCSF) joins us to cover: the Pfizer-BioNTech and Moderna novel mRNA vaccine mechanisms, trial data, and practicalities of who should receive them. We discuss data around the Oxford-AstraZeneca adenovirus vaccine, which is authorized in the UK and India, and may be available in the US later this year. Feel confident recommending COVID-19 vaccines to your patients! Episodes | Subscribe | Spotify | Swag! | Top Picks | Mailing List | thecurbsiders@gmail.com | Free CME! Credits Written and Produced by: Molly Heublein, MD Cover Art: Chris Chiu, MD, FACP, FAAP Infographic: Tima Karginov Hosts: Chris Chiu, MD, FACP, FAAP; Molly Heublein, MD; Paul Williams, MD, FACP Editor: Emi Okamoto MD (written materials); Clair Morgan of Nodderly.com (audio) Guest: Monica Gandhi, MD, MPH Sponsor: Panacea Financial This episode is supported by Panacea Financial, digital banking built for doctors, by doctors. At Panacea Financial you can have your own free personal banker and a support team that works around the clock- just like you do. Open your free checking account today at panaceafinancial.com Panacea Financial, a Division of Sonabank, Member FDIC Sponsor: VCU Health CE The Curbsiders are partnering with VCU Health Continuing Education to offer FREE continuing education credits for physicians and other healthcare professionals. Visit curbsiders.vcuhealth.org . Time Stamps Intro, disclaimer, guest bio - 00:00 Guest one-liner, book recommendation - 3:40 Authorized vaccines in the US - 8:30 AstraZeneca vaccine mechanism- 9:26 mRNA vaccine mechanism - 10:30 Vaccine distribution issues (cold chain) - 16:05 mRNA safety - 18:24 mRNA vaccine efficacy/data from phase 3 trials - 19:40 How did we get this so quickly - 23:40 Vaccine impact on asymptomatic infection - 26:18 AstraZeneca trials - 28:20 Pregnancy - 35:10 Anaphylaxis - 37:10 Prior COVID-19 infection - 39:07 Side effects - 42:05 Pediatric patients - 45:12 Phases of role outs in the US -46:50 Herd immunity - 48:16 Thoughts of how to make this happen - 52:45 Preexisting conditions - 53:40 How long will immunity last - 57:15 Mutant strains - 58:25 Future of mRNA vaccines - 1:00:30 Take home points and Outro - 1:02:12