RAPID REACT: 49ers Come out HOT in Brock Purdy's Return vs the Arizona Cardinals

The San Francisco 49ers steamrolled the Arizona Cardinals 41-22 as Brock Purdy made a triumphant return. Christian McCaffrey exploded with three touchdowns, George Kittle dominated for two more, and the 49ers controlled every phase of the game with explosive plays, efficient offense, and game-changing special teams. Despite Jacoby Brissett’s surprising 47 completions, the Cardinals’ relentless penalties and turnovers kept them on their heels all afternoon. San Francisco 49ers fans are treated to daily news and analysis with Locked On 49ers, hosted by football analyst Brian Peacock and former NFL/AFL cornerback Eric Crocker. Follow & Subscribe on all Podcast platforms… 🎧 https://link.chtbl.com/LO49ers?sid=YouTube Locked On NFL League-Wide: Every Team, Fantasy, Draft & More 🎧 https://linktr.ee/LockedOnNFL Follow Brian Peacock and Eric Crocker on Twitter, where they’ll be sharing the latest news about the Niners and talking with fans. Twitter: twitter.com/BDPeacock, twitter.com/eric_crocker Support Us By Supporting Our Sponsors! Peloton Let yourself run, lift, flex, and push forward. Explore the new Peloton Cross Training Tread+ today at https://www.onepeloton.com. PrizePicks Download the PrizePicks app today and use code LOCKEDONNFL to get $50 in lineups after you play your first $5 lineup. Click Here: https://prizepicks.onelink.me/LME0/LOCKEDONNFL Gametime Download the Gametime app, create an account, and use code LOCKEDONNFL for $20 off your first purchase. Terms apply. Download Gametime today. What time is it? Gametime. FanDuel Right now, new customers can bet just FIVE dollars and if your bet wins—you’ll get THREE HUNDRED dollars in bonus bets to use across the app. FANDUEL DISCLAIMER: 21+ in select states. First online real money wager only. Bonus issued as nonwithdrawable free bets that expires in 14 days. Restrictions apply. See terms at sportsbook.fanduel.com. Gambling Problem? Call 1-800-GAMBLER or visit FanDuel.com/RG (CO, IA, MD, MI, NJ, PA, IL, VA, WV), 1-800-NEXT-STEP or text NEXTSTEP to 53342 (AZ), 1-888-789-7777 or visit ccpg.org/chat (CT), 1-800-9-WITH-IT (IN), 1-800-522-4700 (WY, KS) or visit ksgamblinghelp.com (KS), 1-877-770-STOP (LA), 1-877-8-HOPENY or text HOPENY (467369) (NY), TN REDLINE 1-800-889-9789 (TN) Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.