WEEK 4 CLASH: Can the 49ers Overcome DEVASTATING Nick Bosa Injury vs Jaguars?

49ers vs Jaguars: Clash of Titans or Battle of Attrition? San Francisco 49ers face a crucial test against the Jacksonville Jaguars in Week 4. With Nick Bosa sidelined, can the 49ers' defense hold strong? Christian McCaffrey's explosive potential clashes with Trevor Lawrence's quest for consistency. Locked On hosts Brian Peacock and Tony Wiggins break down key matchups, dissect game-changing strategies, and offer insider perspectives on this high-stakes showdown. San Francisco 49ers fans are treated to daily news and analysis with Locked On 49ers, hosted by football analyst Brian Peacock and former NFL/AFL cornerback Eric Crocker. Follow & Subscribe on all Podcast platforms… 🎧 https://link.chtbl.com/LO49ers?sid=YouTube Locked On NFL League-Wide: Every Team, Fantasy, Draft & More 🎧 https://linktr.ee/LockedOnNFL Follow Brian Peacock and Eric Crocker on Twitter, where they’ll be sharing the latest news about the Niners and talking with fans. Twitter: twitter.com/BDPeacock, twitter.com/eric_crocker Support Us By Supporting Our Sponsors! 5-Hour ENERGY Enough with boring, flavorless caffeine, it’s time to give your caffeine a flavor upgrade with 5-hour ENERGY®️ shots. Get the favorites you love or be bold and try something new in-store and online at https://www.5hourENERGY.com or Amazon today. DoorDash With DoorDash Streaks, you save every Saturday you order — stack it up all season and you could save up to $250. Order this Saturday. Keep the streak alive. Fuel your gameday — only with DoorDash. Terms apply. Promo period through 11/18. Square To learn more, go support your favorite neighborhood spot and see what Square has been up to in your neck of the woods. And then if you have extra time, check out https://square.com/go/lockedonnfl. PrizePicks Download the PrizePicks app today and use code LOCKEDONNFL to get $50 in lineups after you play your first $5 lineup. Gametime Download the Gametime app, create an account, and use code LOCKEDONNFL for $20 off your first purchase. Terms apply. Download Gametime today. What time is it? Gametime. FanDuel Right now, new customers can bet just FIVE dollars and if your bet wins—you’ll get THREE HUNDRED dollars in bonus bets to use across the app. FANDUEL DISCLAIMER: 21+ in select states. First online real money wager only. Bonus issued as nonwithdrawable free bets that expires in 14 days. Restrictions apply. See terms at sportsbook.fanduel.com. Gambling Problem? Call 1-800-GAMBLER or visit FanDuel.com/RG (CO, IA, MD, MI, NJ, PA, IL, VA, WV), 1-800-NEXT-STEP or text NEXTSTEP to 53342 (AZ), 1-888-789-7777 or visit ccpg.org/chat (CT), 1-800-9-WITH-IT (IN), 1-800-522-4700 (WY, KS) or visit ksgamblinghelp.com (KS), 1-877-770-STOP (LA), 1-877-8-HOPENY or text HOPENY (467369) (NY), TN REDLINE 1-800-889-9789 (TN) Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.