With an ovary removed, when should I think about increasing progesterone or estrogen? | Masterjohn Q&A Files #110

Question: With an ovary removed, when should I think about increasing progesterone or estrogen? Carrie: You may actually need more progesterone. Like I was saying in the very beginning of this, that progesterone actually turns into that neurosteroid allopregnanolone, which can cross the blood-brain barrier and bind itself to GABA and affect sleep. It's very calming, obviously relaxing. It's GABA. Carrie: Obviously, there are other things that affect sleep too. If your norepinephrine is going up at night, if you got blood sugar issues, if your cortisol is going up at night -- and norepinephrine is a big trigger for hot flashes for women, especially night sweats. It's one of its symptoms. Women think it's hot flashes and night sweats from hormones and really it's from norepinephrine. Getting stress under control, winding down at night, those things, if you're on any kind of adrenal support, nourishing adrenal as opposed to stimulating adrenal can be really helpful also. This Q&A can also be found as part of a much longer episode, here: https://chrismasterjohnphd.com/podcast/2019/10/19/ask-us-anything-hormones-dr-carrie-jones-may-10-2019 If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up with a 10% lifetime discount here: https://chrismasterjohnphd.com/q&a ====== DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice. PLEASE NOTE: As a result of the COVID-19 crisis and the time I am committing to staying on top of relevant research, as well as the high volume of questions I receive, it may take me extra time to respond to questions here. For an up-to-date list of where I respond to questions most quickly, please see the contact page on chrismasterjohnphd.com. Access the show notes, transcript, and comments here . Chris Masterjohn, PhD, is the Founder and Scientific Director of the mitochondria test Mitome .